C1QTNF7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1glomerular basement membrane development (GO:0032836)6.88791350
2negative regulation of cardiac muscle cell apoptotic process (GO:0010667)6.17481203
3glomerulus development (GO:0032835)6.09182577
4glomerular visceral epithelial cell development (GO:0072015)5.71792772
5peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)5.62962513
6coronary vasculature morphogenesis (GO:0060977)5.50283665
7Notch signaling involved in heart development (GO:0061314)5.26288880
8hyperosmotic salinity response (GO:0042538)5.25719670
9relaxation of smooth muscle (GO:0044557)5.25398144
10vascular smooth muscle contraction (GO:0014829)5.20371168
11glomerular epithelial cell development (GO:0072310)5.13876698
12lymph vessel development (GO:0001945)5.08303165
13negative regulation of smooth muscle cell differentiation (GO:0051151)5.07771438
14regulation of response to osmotic stress (GO:0047484)5.03763587
15positive regulation of endothelial cell apoptotic process (GO:2000353)4.93016251
16negative regulation of cytosolic calcium ion concentration (GO:0051481)4.86635602
17hypotonic response (GO:0006971)4.79243306
18heart valve formation (GO:0003188)4.71046544
19keratan sulfate catabolic process (GO:0042340)4.61752173
20limb bud formation (GO:0060174)4.61054126
21regulation of vasculogenesis (GO:2001212)4.59992636
22ventricular trabecula myocardium morphogenesis (GO:0003222)4.43051092
23atrial septum morphogenesis (GO:0060413)4.39040541
24pre-miRNA processing (GO:0031054)4.38595602
25cardiac right ventricle morphogenesis (GO:0003215)4.32879981
26cGMP-mediated signaling (GO:0019934)4.23643779
27negative regulation of striated muscle cell apoptotic process (GO:0010664)4.19089784
28heart trabecula formation (GO:0060347)4.18134525
29positive regulation of vascular permeability (GO:0043117)4.09746656
30protein heterotrimerization (GO:0070208)4.08555929
31positive regulation of glycolytic process (GO:0045821)4.07896159
32extracellular fibril organization (GO:0043206)4.07647331
33protein localization to cell surface (GO:0034394)4.05087670
34regulation of cardiac muscle cell apoptotic process (GO:0010665)4.04654765
35positive regulation of cardiac muscle tissue growth (GO:0055023)3.88795182
36positive regulation of phosphoprotein phosphatase activity (GO:0032516)3.87636424
37blood vessel maturation (GO:0001955)3.84089513
38cardiac left ventricle morphogenesis (GO:0003214)3.80769411
39positive regulation of inositol phosphate biosynthetic process (GO:0060732)3.80072010
40negative regulation of vascular permeability (GO:0043116)3.78706286
41metanephric mesenchyme development (GO:0072075)3.74513277
42relaxation of cardiac muscle (GO:0055119)3.73380472
43smooth muscle cell differentiation (GO:0051145)3.70842630
44regulation of axon extension involved in axon guidance (GO:0048841)3.70822229
45positive regulation of cardiac muscle tissue development (GO:0055025)3.69035414
46positive regulation of heart growth (GO:0060421)3.66655908
47kidney mesenchyme development (GO:0072074)3.65099734
48lung vasculature development (GO:0060426)3.64634443
49trabecula formation (GO:0060343)3.62786498
50cardiac epithelial to mesenchymal transition (GO:0060317)3.62684480
51smooth muscle tissue development (GO:0048745)3.61363197
52tonic smooth muscle contraction (GO:0014820)3.60249795
53retina vasculature morphogenesis in camera-type eye (GO:0061299)3.57344156
54histone mRNA catabolic process (GO:0071044)3.57303388
55positive regulation of heart rate (GO:0010460)3.56354046
56dermatan sulfate biosynthetic process (GO:0030208)3.55935002
57mesenchymal cell development (GO:0014031)3.53664378
58cardiac muscle adaptation (GO:0014887)3.51599648
59cardiac muscle hypertrophy in response to stress (GO:0014898)3.51599648
60muscle hypertrophy in response to stress (GO:0003299)3.51599648
61regulation of smooth muscle cell differentiation (GO:0051150)3.49998305
62regulation of striated muscle cell apoptotic process (GO:0010662)3.47578312
63positive regulation of cardiac muscle cell differentiation (GO:2000727)3.46195030
64positive regulation of cardiac muscle cell proliferation (GO:0060045)3.43396137
65tryptophan catabolic process (GO:0006569)3.41488523
66indole-containing compound catabolic process (GO:0042436)3.41488523
67indolalkylamine catabolic process (GO:0046218)3.41488523
68collagen fibril organization (GO:0030199)3.38794119
69vascular endothelial growth factor signaling pathway (GO:0038084)3.35010887
70heart trabecula morphogenesis (GO:0061384)3.34973624
71fibril organization (GO:0097435)3.33746092
72adult feeding behavior (GO:0008343)3.33115304
73sequestering of extracellular ligand from receptor (GO:0035581)3.32622732
74regulation of axon guidance (GO:1902667)3.32274803
75extracellular matrix assembly (GO:0085029)3.31473474
76mesenchymal cell differentiation involved in renal system development (GO:2001012)3.30059217
77mesenchymal cell differentiation involved in kidney development (GO:0072161)3.30059217
78venous blood vessel morphogenesis (GO:0048845)3.28744083
79negative regulation of complement activation (GO:0045916)3.28619879
80regulation of energy homeostasis (GO:2000505)3.28546720
81regulation of lipopolysaccharide-mediated signaling pathway (GO:0031664)3.28069714
82fatty acid homeostasis (GO:0055089)3.26323859
83heart valve morphogenesis (GO:0003179)3.25091610
84cell adhesion mediated by integrin (GO:0033627)3.23181624
85dermatan sulfate metabolic process (GO:0030205)3.23163606
86positive regulation of uterine smooth muscle contraction (GO:0070474)3.22480684
87glomerular filtration (GO:0003094)3.17981052
88regulation of cardiac muscle cell differentiation (GO:2000725)3.17208110
89fatty acid transmembrane transport (GO:1902001)3.15813812
90cell proliferation involved in kidney development (GO:0072111)3.14622243
91negative regulation of macrophage derived foam cell differentiation (GO:0010745)3.14256598
92aorta morphogenesis (GO:0035909)3.14100560
93lymphangiogenesis (GO:0001946)3.12578165
94basement membrane organization (GO:0071711)3.12423334
95gonadal mesoderm development (GO:0007506)3.11476822
96ventricular cardiac muscle cell development (GO:0055015)3.10059802
97regulation of neuron migration (GO:2001222)3.08781090
98endothelial cell differentiation (GO:0045446)3.08392793
99regulation of cardiac muscle tissue growth (GO:0055021)3.08091576
100regulation of sequestering of triglyceride (GO:0010889)3.07857987
101renal filtration (GO:0097205)3.07027623
102artery development (GO:0060840)3.06759192
103membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.04855138
104radial glial cell differentiation (GO:0060019)3.04527907
105cell proliferation involved in metanephros development (GO:0072203)3.03462666
106regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO3.02538529
107regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)3.00251895
108regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.00244835
109atrioventricular valve morphogenesis (GO:0003181)2.99584651
110cardiac muscle hypertrophy (GO:0003300)2.96963827
111peripheral nervous system axon ensheathment (GO:0032292)2.96885148
112myelination in peripheral nervous system (GO:0022011)2.96885148
113ventricular septum morphogenesis (GO:0060412)2.96800059
114bone trabecula formation (GO:0060346)2.96285335
115regulation of inositol phosphate biosynthetic process (GO:0010919)2.94147954
116carnitine shuttle (GO:0006853)2.94076356
117trabecula morphogenesis (GO:0061383)2.92470832
118stem cell development (GO:0048864)2.91383387
119regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)2.90989825
120response to caffeine (GO:0031000)2.87716563
121cardiac chamber morphogenesis (GO:0003206)2.87177881
122cell migration involved in heart development (GO:0060973)2.86416253
123positive regulation of fatty acid oxidation (GO:0046321)2.84285381
124endocardial cushion morphogenesis (GO:0003203)2.83714500
125relaxation of muscle (GO:0090075)2.82955200
126striated muscle hypertrophy (GO:0014897)2.81456223
127positive regulation of endothelial cell differentiation (GO:0045603)2.81447081
128kidney morphogenesis (GO:0060993)2.81352686
129regulation of endothelial cell differentiation (GO:0045601)2.80864925
130endocrine hormone secretion (GO:0060986)2.80256623
131endothelium development (GO:0003158)2.79656461
132positive regulation of smooth muscle cell migration (GO:0014911)2.77153185
133positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.76906414
134cell surface receptor signaling pathway involved in heart development (GO:0061311)2.76668353
135positive regulation of glucose import (GO:0046326)2.75701082
136tryptophan metabolic process (GO:0006568)2.75575281
137cell differentiation involved in metanephros development (GO:0072202)2.74375250
138regulation of heart growth (GO:0060420)2.73989503
139regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.72955343
140corticosteroid receptor signaling pathway (GO:0031958)2.72767269
141cardiac ventricle morphogenesis (GO:0003208)2.72268691
142smooth muscle contraction (GO:0006939)2.71392922
143muscle hypertrophy (GO:0014896)2.70921491
144cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.70834534
145positive regulation of heart contraction (GO:0045823)2.70409111
146cellular sodium ion homeostasis (GO:0006883)2.69759029
147cell volume homeostasis (GO:0006884)2.69689140
148otic vesicle formation (GO:0030916)2.69182683
149dendritic spine morphogenesis (GO:0060997)2.69061118
150clathrin coat assembly (GO:0048268)2.69020073
151calcium ion import (GO:0070509)2.68163320
152polyol transport (GO:0015791)2.65745688
153negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804)2.64419743
154cellular response to osmotic stress (GO:0071470)2.64148838
155negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642)2.61367342
156positive regulation of vasculogenesis (GO:2001214)2.60652590
157mesenchymal-epithelial cell signaling (GO:0060638)2.55889922
158low-density lipoprotein particle clearance (GO:0034383)2.52619752
159negative regulation of protein activation cascade (GO:2000258)2.51939241
160vasoconstriction (GO:0042310)2.48571579
161embryonic camera-type eye development (GO:0031076)2.45680214
162detection of light stimulus involved in sensory perception (GO:0050962)2.45546505
163detection of light stimulus involved in visual perception (GO:0050908)2.45546505
164carnitine transmembrane transport (GO:1902603)2.45408436
165regulation of non-canonical Wnt signaling pathway (GO:2000050)2.44392184
166embryonic placenta development (GO:0001892)2.43970364
167positive regulation of glomerulus development (GO:0090193)2.40123212
168embryonic heart tube development (GO:0035050)2.39300255
169cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.36387640
170embryonic digestive tract morphogenesis (GO:0048557)2.36023280
171outer ear morphogenesis (GO:0042473)2.35427924
172spinal cord motor neuron differentiation (GO:0021522)2.34206594
173chemical homeostasis within a tissue (GO:0048875)2.32615022
174keratan sulfate biosynthetic process (GO:0018146)2.30095485
175lung lobe morphogenesis (GO:0060463)2.29655626
176negative regulation of systemic arterial blood pressure (GO:0003085)2.27796422
177positive regulation of glucose transport (GO:0010828)2.27393773
178platelet-derived growth factor receptor signaling pathway (GO:0048008)2.27002858
179regulation of protein kinase A signaling (GO:0010738)2.26160616
180establishment of protein localization to Golgi (GO:0072600)2.25940136
181ovulation from ovarian follicle (GO:0001542)2.25827281

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRIM28_21343339_ChIP-Seq_HEK293_Human4.56579543
2GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.02992342
3EED_16625203_ChIP-ChIP_MESCs_Mouse2.88469390
4IGF1R_20145208_ChIP-Seq_DFB_Human2.81336970
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.65964142
6* ESR1_22446102_ChIP-Seq_UTERUS_Mouse2.59568073
7PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.56542590
8GBX2_23144817_ChIP-Seq_PC3_Human2.55777477
9SMAD_19615063_ChIP-ChIP_OVARY_Human2.55195900
10SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.37142868
11SALL1_21062744_ChIP-ChIP_HESCs_Human2.32599553
12EP300_21415370_ChIP-Seq_HL-1_Mouse2.26898894
13SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.23079069
14SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.19428738
15SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.15489754
16CDX2_19796622_ChIP-Seq_MESCs_Mouse2.12206987
17RNF2_16625203_ChIP-ChIP_MESCs_Mouse2.10648524
18EZH2_18974828_ChIP-Seq_MESCs_Mouse2.06996283
19RNF2_18974828_ChIP-Seq_MESCs_Mouse2.06996283
20CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse2.06531760
21RARG_19884340_ChIP-ChIP_MEFs_Mouse2.05003610
22CJUN_26792858_Chip-Seq_BT549_Human2.01685415
23PHC1_16625203_ChIP-ChIP_MESCs_Mouse2.01680747
24ESR1_21235772_ChIP-Seq_MCF-7_Human1.93950547
25WT1_19549856_ChIP-ChIP_CCG9911_Human1.89011633
26JARID2_20075857_ChIP-Seq_MESCs_Mouse1.84916793
27CLOCK_20551151_ChIP-Seq_293T_Human1.82956595
28CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.81481308
29MTF2_20144788_ChIP-Seq_MESCs_Mouse1.80883139
30JARID2_20064375_ChIP-Seq_MESCs_Mouse1.75669869
31PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.73949559
32VDR_22108803_ChIP-Seq_LS180_Human1.73800719
33GATA2_21666600_ChIP-Seq_HMVEC_Human1.71238872
34PIAS1_25552417_ChIP-Seq_VCAP_Human1.66514993
35EZH2_22144423_ChIP-Seq_EOC_Human1.66503158
36POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.62436864
37TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.62436864
38ESR1_20079471_ChIP-ChIP_T-47D_Human1.62053142
39RNF2_27304074_Chip-Seq_ESCs_Mouse1.61988269
40EZH2_27304074_Chip-Seq_ESCs_Mouse1.61913838
41GATA1_22025678_ChIP-Seq_K562_Human1.58908818
42TP53_16413492_ChIP-PET_HCT116_Human1.58400237
43TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.55224734
44TP53_18474530_ChIP-ChIP_U2OS_Human1.54439120
45NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.52239733
46NRF2_20460467_ChIP-Seq_MEFs_Mouse1.52239733
47BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.51523672
48ZNF217_24962896_ChIP-Seq_MCF-7_Human1.50197726
49TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.49036821
50RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.47277131
51FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.45731539
52TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.45264958
53BCAT_22108803_ChIP-Seq_LS180_Human1.44257146
54FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.43659747
55SUZ12_27294783_Chip-Seq_ESCs_Mouse1.42986540
56AR_21572438_ChIP-Seq_LNCaP_Human1.42078449
57EZH2_27294783_Chip-Seq_ESCs_Mouse1.40463881
58SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.40061495
59STAT3_23295773_ChIP-Seq_U87_Human1.36268427
60HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.33610749
61AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.31895113
62ARNT_22903824_ChIP-Seq_MCF-7_Human1.30987032
63GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.28946734
64IKZF1_21737484_ChIP-ChIP_HCT116_Human1.28630761
65AHR_22903824_ChIP-Seq_MCF-7_Human1.27634434
66CBX2_27304074_Chip-Seq_ESCs_Mouse1.27019176
67* RUNX2_22187159_ChIP-Seq_PCA_Human1.26962960
68HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.26698922
69CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.25249631
70MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.23796910
71TP53_20018659_ChIP-ChIP_R1E_Mouse1.23030777
72ESR2_21235772_ChIP-Seq_MCF-7_Human1.22637326
73EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.21654826
74FUS_26573619_Chip-Seq_HEK293_Human1.21516556
75IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.17601379
76CBP_20019798_ChIP-Seq_JUKART_Human1.17601379
77CTNNB1_20460455_ChIP-Seq_HCT116_Human1.17348048
78CTBP2_25329375_ChIP-Seq_LNCAP_Human1.16101744
79CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.15861900
80HTT_18923047_ChIP-ChIP_STHdh_Human1.15852458
81SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.14945458
82SMAD4_21799915_ChIP-Seq_A2780_Human1.14838746
83TAF15_26573619_Chip-Seq_HEK293_Human1.14256211
84WT1_25993318_ChIP-Seq_PODOCYTE_Human1.13534940
85ZFP57_27257070_Chip-Seq_ESCs_Mouse1.13194733
86* TCF4_23295773_ChIP-Seq_U87_Human1.12655942
87MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.11507146
88BP1_19119308_ChIP-ChIP_Hs578T_Human1.11102125
89STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.10853027
90ISL1_27105846_Chip-Seq_CPCs_Mouse1.10570088
91EZH2_27294783_Chip-Seq_NPCs_Mouse1.09402200
92NR3C1_21868756_ChIP-Seq_MCF10A_Human1.09063257
93CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08072687
94BMI1_23680149_ChIP-Seq_NPCS_Mouse1.07599309
95FLI1_27457419_Chip-Seq_LIVER_Mouse1.07035363
96P300_19829295_ChIP-Seq_ESCs_Human1.06552044
97SMAD4_21741376_ChIP-Seq_HESCs_Human1.04747306
98* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.04106780
99TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.03922373
100TOP2B_26459242_ChIP-Seq_MCF-7_Human1.03779050
101POU3F2_20337985_ChIP-ChIP_501MEL_Human1.03662132
102SMAD3_21741376_ChIP-Seq_EPCs_Human1.03429559
103SALL4_18804426_ChIP-ChIP_XEN_Mouse1.02860330
104SMAD3_21741376_ChIP-Seq_HESCs_Human1.02143299
105* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.02043110
106DROSHA_22980978_ChIP-Seq_HELA_Human1.01778666
107* KDM2B_26808549_Chip-Seq_REH_Human1.01697533
108* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01364379
109SMAD4_21741376_ChIP-Seq_EPCs_Human1.01297819
110TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.00824935
111PCGF2_27294783_Chip-Seq_NPCs_Mouse1.00647424
112* BRD4_25478319_ChIP-Seq_HGPS_Human1.00610171
113* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.99756258
114TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.98188406
115VDR_24787735_ChIP-Seq_THP-1_Human0.97881959
116SOX2_20726797_ChIP-Seq_SW620_Human0.97794962
117CTBP1_25329375_ChIP-Seq_LNCAP_Human0.97371520
118PPAR_26484153_Chip-Seq_NCI-H1993_Human0.97299656
119RING1B_27294783_Chip-Seq_ESCs_Mouse0.97061769
120RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.96534226
121SOX2_21211035_ChIP-Seq_LN229_Gbm0.96051455
122ER_23166858_ChIP-Seq_MCF-7_Human0.95864806
123FOXM1_26456572_ChIP-Seq_MCF-7_Human0.95459861
124UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.95339962
125CDX2_22108803_ChIP-Seq_LS180_Human0.95328506
126PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.94976164
127CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.94723720
128TP63_17297297_ChIP-ChIP_HaCaT_Human0.94664037
129* NR3C1_23031785_ChIP-Seq_PC12_Mouse0.91240061
130RING1B_27294783_Chip-Seq_NPCs_Mouse0.90533904
131* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.88642364
132STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.88638998
133AR_25329375_ChIP-Seq_VCAP_Human0.88106138
134PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.87877769
135TBX20_22328084_ChIP-Seq_HEART_Mouse0.86649712

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen6.69406333
2MP0005503_abnormal_tendon_morphology6.27592816
3MP0009384_cardiac_valve_regurgitation5.11266963
4MP0005670_abnormal_white_adipose4.66663266
5MP0005275_abnormal_skin_tensile4.39423050
6MP0004272_abnormal_basement_membrane4.16074657
7MP0010368_abnormal_lymphatic_system3.54230644
8MP0001879_abnormal_lymphatic_vessel3.46400174
9MP0003880_abnormal_central_pattern3.21833532
10MP0003279_aneurysm3.06401960
11MP0001958_emphysema2.96486355
12MP0005423_abnormal_somatic_nervous2.90539168
13MP0002009_preneoplasia2.77354197
14MP0002108_abnormal_muscle_morphology2.34959171
15MP0010030_abnormal_orbit_morphology2.33958508
16MP0004130_abnormal_muscle_cell2.28400454
17MP0001542_abnormal_bone_strength2.23159776
18MP0002295_abnormal_pulmonary_circulatio2.17060039
19MP0000767_abnormal_smooth_muscle2.10509842
20MP0005666_abnormal_adipose_tissue2.09721789
21MP0002127_abnormal_cardiovascular_syste2.05158804
22MP0006138_congestive_heart_failure2.03264059
23MP0006054_spinal_hemorrhage2.02762565
24MP0002876_abnormal_thyroid_physiology2.01072976
25MP0005248_abnormal_Harderian_gland2.00661765
26MP0003828_pulmonary_edema1.94541039
27MP0005508_abnormal_skeleton_morphology1.90552853
28MP0000751_myopathy1.73932579
29MP0005595_abnormal_vascular_smooth1.72273609
30MP0003941_abnormal_skin_development1.70659353
31MP0009115_abnormal_fat_cell1.64442781
32MP0009278_abnormal_bone_marrow1.57475171
33MP0001661_extended_life_span1.54174494
34MP0002102_abnormal_ear_morphology1.52514837
35MP0005171_absent_coat_pigmentation1.51407906
36MP0002638_abnormal_pupillary_reflex1.50236365
37MP0003045_fibrosis1.49752820
38MP0010386_abnormal_urinary_bladder1.49042341
39MP0002971_abnormal_brown_adipose1.49037097
40MP0005375_adipose_tissue_phenotype1.48192197
41MP0000569_abnormal_digit_pigmentation1.44980884
42MP0002282_abnormal_trachea_morphology1.44138412
43MP0002249_abnormal_larynx_morphology1.43570878
44MP0003942_abnormal_urinary_system1.40666900
45MP0003115_abnormal_respiratory_system1.38856685
46MP0000749_muscle_degeneration1.34212425
47MP0004484_altered_response_of1.34203364
48MP0005551_abnormal_eye_electrophysiolog1.33679877
49MP0005623_abnormal_meninges_morphology1.33358984
50MP0006276_abnormal_autonomic_nervous1.32813927
51MP0000013_abnormal_adipose_tissue1.32192410
52MP0003385_abnormal_body_wall1.31224515
53MP0000534_abnormal_ureter_morphology1.30865344
54MP0004133_heterotaxia1.29848503
55MP0005620_abnormal_muscle_contractility1.28812368
56MP0002060_abnormal_skin_morphology1.28577438
57MP0005164_abnormal_response_to1.27083957
58MP0003705_abnormal_hypodermis_morpholog1.25658183
59MP0005388_respiratory_system_phenotype1.25360602
60MP0002133_abnormal_respiratory_system1.25360602
61MP0004084_abnormal_cardiac_muscle1.25086707
62MP0002972_abnormal_cardiac_muscle1.23125981
63MP0008004_abnormal_stomach_pH1.20854726
64MP0005385_cardiovascular_system_phenoty1.20587558
65MP0001544_abnormal_cardiovascular_syste1.20587558
66MP0003950_abnormal_plasma_membrane1.19761794
67MP0004036_abnormal_muscle_relaxation1.16930854
68MP0002735_abnormal_chemical_nociception1.16567215
69MP0004883_abnormal_blood_vessel1.16155323
70MP0003724_increased_susceptibility_to1.15312164
71MP0000230_abnormal_systemic_arterial1.14893240
72MP0002128_abnormal_blood_circulation1.14569607
73MP0003011_delayed_dark_adaptation1.14549704
74MP0002938_white_spotting1.11453245
75MP0004085_abnormal_heartbeat1.10579828
76MP0001175_abnormal_lung_morphology1.10001809
77MP0008775_abnormal_heart_ventricle1.09717643
78MP0002837_dystrophic_cardiac_calcinosis1.07623574
79MP0001299_abnormal_eye_distance/1.07103635
80MP0000249_abnormal_blood_vessel1.07032591
81MP0009250_abnormal_appendicular_skeleto1.06879831
82MP0000163_abnormal_cartilage_morphology1.06473640
83MP0005330_cardiomyopathy1.06291658
84MP0004215_abnormal_myocardial_fiber1.04545510
85MP0001614_abnormal_blood_vessel1.02423178
86MP0003868_abnormal_feces_composition1.02331936
87MP0005165_increased_susceptibility_to1.02330149
88MP0005448_abnormal_energy_balance0.98715367
89MP0000566_synostosis0.98005266
90MP0003890_abnormal_embryonic-extraembry0.96824866
91MP0001986_abnormal_taste_sensitivity0.96630467
92MP0005023_abnormal_wound_healing0.95556454
93MP0002166_altered_tumor_susceptibility0.94231007
94MP0002909_abnormal_adrenal_gland0.93953404
95MP0005367_renal/urinary_system_phenotyp0.91692427
96MP0000516_abnormal_urinary_system0.91692427
97MP0003252_abnormal_bile_duct0.90597955
98MP0009697_abnormal_copulation0.90060551
99MP0002254_reproductive_system_inflammat0.89172837
100MP0002925_abnormal_cardiovascular_devel0.86700381
101MP0003959_abnormal_lean_body0.86697370
102MP0005167_abnormal_blood-brain_barrier0.86023462
103MP0003566_abnormal_cell_adhesion0.85884333
104MP0005390_skeleton_phenotype0.85435359
105MP0001545_abnormal_hematopoietic_system0.85370421
106MP0005397_hematopoietic_system_phenotyp0.85370421
107MP0000049_abnormal_middle_ear0.85048822
108MP0000462_abnormal_digestive_system0.84714518
109MP0000343_altered_response_to0.80308990
110MP0002933_joint_inflammation0.79975521
111MP0005369_muscle_phenotype0.79658834
112MP0001756_abnormal_urination0.78889890
113MP0005253_abnormal_eye_physiology0.78593431
114MP0003938_abnormal_ear_development0.78391700
115MP0002877_abnormal_melanocyte_morpholog0.78360325
116MP0000678_abnormal_parathyroid_gland0.77428308
117MP0001270_distended_abdomen0.76935326
118MP0009780_abnormal_chondrocyte_physiolo0.76447435
119MP0003122_maternal_imprinting0.76393636
120MP0002115_abnormal_skeleton_extremities0.75890065
121MP0000537_abnormal_urethra_morphology0.75355878
122MP0001486_abnormal_startle_reflex0.74786143
123MP0005084_abnormal_gallbladder_morpholo0.74432007
124MP0006072_abnormal_retinal_apoptosis0.73638228
125MP0001501_abnormal_sleep_pattern0.73234550
126MP0001177_atelectasis0.71844759
127MP0004087_abnormal_muscle_fiber0.69031728
128MP0002168_other_aberrant_phenotype0.68850356
129MP0010630_abnormal_cardiac_muscle0.67067199
130MP0001243_abnormal_dermal_layer0.65253793
131MP0000762_abnormal_tongue_morphology0.64536201
132MP0002138_abnormal_hepatobiliary_system0.64422210
133MP0000266_abnormal_heart_morphology0.63294914
134MP0000003_abnormal_adipose_tissue0.63160325
135MP0002135_abnormal_kidney_morphology0.62652148
136MP0002970_abnormal_white_adipose0.62372834
137MP0000733_abnormal_muscle_development0.62237836
138MP0002932_abnormal_joint_morphology0.61871461
139MP0002006_tumorigenesis0.61720632
140MP0010329_abnormal_lipoprotein_level0.60649641
141MP0003567_abnormal_fetal_cardiomyocyte0.60583939
142MP0003935_abnormal_craniofacial_develop0.60265537
143MP0003091_abnormal_cell_migration0.60100254
144MP0005535_abnormal_body_temperature0.59654249
145MP0000613_abnormal_salivary_gland0.59512566
146MP0003300_gastrointestinal_ulcer0.59428160
147MP0002896_abnormal_bone_mineralization0.58157995

Predicted human phenotypes

RankGene SetZ-score
1Aortic aneurysm (HP:0004942)6.56047845
2Muscle fiber splitting (HP:0003555)6.43739126
3Protrusio acetabuli (HP:0003179)5.97107066
4Broad metatarsal (HP:0001783)5.86022192
5Aortic dissection (HP:0002647)5.52276427
6Mesangial abnormality (HP:0001966)5.11309133
7Hip dysplasia (HP:0001385)4.92918830
8Pulmonary artery stenosis (HP:0004415)4.56997283
9Premature rupture of membranes (HP:0001788)4.51362381
10Ankle contracture (HP:0006466)4.47904186
11Difficulty running (HP:0009046)4.47158214
12Aplasia of the musculature (HP:0100854)4.25736209
13Spinal muscular atrophy (HP:0007269)4.23406863
14Diaphragmatic weakness (HP:0009113)4.15919730
15Obstructive sleep apnea (HP:0002870)4.13135901
16Abnormality of the middle phalanges of the toes (HP:0010183)4.09152396
17Vascular tortuosity (HP:0004948)3.87734625
18Cerebral aneurysm (HP:0004944)3.76443094
19Fetal akinesia sequence (HP:0001989)3.74730499
20Follicular hyperkeratosis (HP:0007502)3.72840055
21Carpal bone hypoplasia (HP:0001498)3.52690681
22Stridor (HP:0010307)3.49899570
23Hand muscle atrophy (HP:0009130)3.44169108
24Spinal cord compression (HP:0002176)3.41734075
25Short tibia (HP:0005736)3.35532111
26Aplasia/Hypoplasia of the tibia (HP:0005772)3.34294259
27Bladder diverticulum (HP:0000015)3.33490488
28Calf muscle hypertrophy (HP:0008981)3.30406299
29Wrist flexion contracture (HP:0001239)3.26595899
30Vertebral compression fractures (HP:0002953)3.24389028
31Limb-girdle muscle atrophy (HP:0003797)3.22799891
32Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)3.16126395
33Spinal rigidity (HP:0003306)3.14036850
34Shallow orbits (HP:0000586)3.12910853
35Short hallux (HP:0010109)3.10414051
36Abnormality of the phalanges of the hallux (HP:0010057)3.08799214
37Hypoplasia of the odontoid process (HP:0003311)3.08515978
38Soft skin (HP:0000977)3.04188757
39Glomerulonephritis (HP:0000099)3.00474458
40Persistence of primary teeth (HP:0006335)2.97943710
41Tubulointerstitial nephritis (HP:0001970)2.97611254
42Supernumerary spleens (HP:0009799)2.96292177
43Scapular winging (HP:0003691)2.93146890
44Stage 5 chronic kidney disease (HP:0003774)2.89510666
45Abnormality of the calf musculature (HP:0001430)2.88717899
46Gowers sign (HP:0003391)2.87108829
47Down-sloping shoulders (HP:0200021)2.85965728
48Midline defect of the nose (HP:0004122)2.85011817
49Muscle hypertrophy of the lower extremities (HP:0008968)2.82581508
50Abnormal vertebral ossification (HP:0100569)2.81402903
51Aneurysm (HP:0002617)2.77418258
52Barrel-shaped chest (HP:0001552)2.76988541
53Abnormality of the distal phalanges of the toes (HP:0010182)2.76982736
54Wormian bones (HP:0002645)2.74924611
55Nephritis (HP:0000123)2.74292113
56Metaphyseal dysplasia (HP:0100255)2.73240535
57Aplasia/Hypoplasia of the hallux (HP:0008362)2.71559191
58Distal upper limb amyotrophy (HP:0007149)2.70869079
59Upper limb amyotrophy (HP:0009129)2.70869079
60Focal segmental glomerulosclerosis (HP:0000097)2.70564746
61Lymphangioma (HP:0100764)2.68298737
62Distal lower limb muscle weakness (HP:0009053)2.64992275
63Cervical subluxation (HP:0003308)2.63538005
64Broad-based gait (HP:0002136)2.60033913
65Epiphyseal dysplasia (HP:0002656)2.58782970
66Aplasia/Hypoplasia involving the musculature (HP:0001460)2.55699513
67Bell-shaped thorax (HP:0001591)2.55298569
68Mesomelia (HP:0003027)2.55067626
69Dilatation of the ascending aorta (HP:0005111)2.52477371
70Disproportionate short-trunk short stature (HP:0003521)2.51228624
71Hematochezia (HP:0002573)2.47696679
72Abnormality of the odontoid process (HP:0003310)2.45884303
73Asymmetry of the thorax (HP:0001555)2.44501373
74Nonprogressive disorder (HP:0003680)2.43641073
75Abnormality of carpal bone ossification (HP:0006257)2.42871399
76Arterial tortuosity (HP:0005116)2.42869520
77Venous insufficiency (HP:0005293)2.41852436
78Shawl scrotum (HP:0000049)2.37708458
79Abnormality of dentin (HP:0010299)2.37291463
80Abnormality of incisor morphology (HP:0011063)2.36386330
81Flat acetabular roof (HP:0003180)2.36247997
82Aortic valve stenosis (HP:0001650)2.35179778
83Sleep apnea (HP:0010535)2.34380592
84Absent frontal sinuses (HP:0002688)2.33504665
85Mitral stenosis (HP:0001718)2.33073695
86Chondrocalcinosis (HP:0000934)2.29245920
87Tubulointerstitial abnormality (HP:0001969)2.28553911
88Camptodactyly of toe (HP:0001836)2.27901526
89Abnormality of Sharpey fibers (HP:0100685)2.26072469
90Blue sclerae (HP:0000592)2.25244665
91Infantile muscular hypotonia (HP:0008947)2.23910251
92Type 1 muscle fiber predominance (HP:0003803)2.21472532
93Glomerulosclerosis (HP:0000096)2.21213771
94Hypoalbuminemia (HP:0003073)2.20919754
95Abnormal albumin level (HP:0012116)2.20919754
96Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.20620430
97Increased variability in muscle fiber diameter (HP:0003557)2.19344031
98Aortic regurgitation (HP:0001659)2.19307741
99Interstitial pulmonary disease (HP:0006530)2.17577167
100Atrophic scars (HP:0001075)2.17071618
101Proximal amyotrophy (HP:0007126)2.16609132
102Short middle phalanx of finger (HP:0005819)2.16002462
103Hypoplasia of the iris (HP:0007676)2.11322986
104Hip contracture (HP:0003273)2.10049233
105Venous abnormality (HP:0002624)2.09299616
106Thin bony cortex (HP:0002753)2.09075631
107Biconcave vertebral bodies (HP:0004586)2.08065100
108Overgrowth (HP:0001548)2.07057152
109Narrow nasal bridge (HP:0000446)2.06917412
110Limited hip movement (HP:0008800)2.06246186
111Increased corneal curvature (HP:0100692)2.05638200
112Keratoconus (HP:0000563)2.05638200
113Abnormality of the vocal cords (HP:0008777)2.04419108
114Mild short stature (HP:0003502)2.02886128
115Enlarged kidneys (HP:0000105)2.02614508
116Abnormal hand bone ossification (HP:0010660)1.99205495
117Joint laxity (HP:0001388)1.98787167
118Coxa vara (HP:0002812)1.96244853
119Tubular atrophy (HP:0000092)1.96195643
120Abnormality of the musculature of the hand (HP:0001421)1.96089245
121Polycythemia (HP:0001901)1.95611780
122Pulmonic stenosis (HP:0001642)1.95521919
123Lipoatrophy (HP:0100578)1.95246457
124Broad ribs (HP:0000885)1.95191169
125Metaphyseal irregularity (HP:0003025)1.94899465
126Abnormality of the shoulder girdle musculature (HP:0001435)1.94680666
127Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.94328666
128Short 4th metacarpal (HP:0010044)1.94328666
129Abnormality of the left ventricular outflow tract (HP:0011103)1.93990445
130Subaortic stenosis (HP:0001682)1.93990445
131Hypoplastic left heart (HP:0004383)1.93147568
132Mitral valve prolapse (HP:0001634)1.92454411
133Atrial fibrillation (HP:0005110)1.91962009
134Slender build (HP:0001533)1.91543880
135Corneal dystrophy (HP:0001131)1.90500108
136Abnormality of skeletal muscle fiber size (HP:0012084)1.89793513
137Osteolytic defects of the hand bones (HP:0009699)1.89618403
138Osteolytic defects of the phalanges of the hand (HP:0009771)1.89618403
139Tarsal synostosis (HP:0008368)1.87999036
140Rimmed vacuoles (HP:0003805)1.87968160
141True hermaphroditism (HP:0010459)1.86993122
142Spontaneous hematomas (HP:0007420)1.86601912
143Alopecia of scalp (HP:0002293)1.85037106
144Abnormal delivery (HP:0001787)1.84980484
145Hypoventilation (HP:0002791)1.84284529
146Fragile skin (HP:0001030)1.84104896
147Aplasia/Hypoplasia of the middle phalanges of the hand (HP:0009843)1.84042710
148Preaxial foot polydactyly (HP:0001841)1.83135220
149Gingival overgrowth (HP:0000212)1.82926425
150Hyperextensible skin (HP:0000974)1.80994891
151Wide anterior fontanel (HP:0000260)1.80776905
152Abnormal ossification of hand bones (HP:0005921)1.80052889
153Absent septum pellucidum (HP:0001331)1.79668802
154Knee flexion contracture (HP:0006380)1.78966596
155Striae distensae (HP:0001065)1.78854024
156Metatarsus adductus (HP:0001840)1.78802821
157Synostosis involving bones of the feet (HP:0009140)1.78647014
158Synostosis involving bones of the lower limbs (HP:0009138)1.78647014
159Ectopia lentis (HP:0001083)1.78207925
160Flared metaphyses (HP:0003015)1.76594949
161Delayed closure of the anterior fontanelle (HP:0001476)1.75122761
162Spondylolisthesis (HP:0003302)1.74951704
163Embryonal renal neoplasm (HP:0011794)1.74395890
164Abnormality of the ischium (HP:0003174)1.73974645
165Mitral regurgitation (HP:0001653)1.73588184
166Aplasia/Hypoplasia of the tongue (HP:0010295)1.73058429
167Torticollis (HP:0000473)1.73051927
168Right ventricular cardiomyopathy (HP:0011663)1.73025130
169Hyperlipoproteinemia (HP:0010980)1.72577947
170Waddling gait (HP:0002515)1.71959658
171Tubulointerstitial fibrosis (HP:0005576)1.71402624
172Papillary thyroid carcinoma (HP:0002895)1.70954842
173Papilledema (HP:0001085)1.70941318
174Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.70690223
175Small hand (HP:0200055)1.70201648
176Tachypnea (HP:0002789)1.69002955
177Abnormality of the middle phalanges of the hand (HP:0009833)1.67229840
178Abnormality of the renal medulla (HP:0100957)1.65891270
179Short femoral neck (HP:0100864)1.65469793

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MYLK7.11502744
2TIE14.83511228
3ZAK3.72736588
4NUAK13.65128177
5DMPK2.74328055
6STK38L2.73854134
7TGFBR22.68637008
8MAP4K22.64746143
9AKT32.62109479
10NLK2.60145150
11BMPR1B2.46083800
12EPHB22.33106541
13EPHA32.30905850
14PDGFRA2.30492982
15PRPF4B2.16814905
16PAK22.13494983
17ERBB31.99824249
18TNIK1.85449639
19MST41.82482068
20FGFR41.70722722
21CLK11.68447379
22ROCK11.61543203
23LATS11.57258484
24PAK31.53743582
25BRD41.52677605
26TTN1.45128890
27DDR21.42480527
28ACVR1B1.39632245
29PTK2B1.39519630
30MAP3K41.33781882
31CDC42BPA1.25000703
32MARK11.23629708
33PRKCE1.20614378
34MAP3K131.19262009
35STK381.14169268
36FER1.11927440
37EPHB11.08722520
38MAP3K61.08486178
39FGFR31.08294535
40GRK51.08115728
41STK241.07290418
42WNK41.06484565
43OBSCN1.01883621
44FRK1.01184837
45CASK0.99987453
46TAOK30.95848600
47PRKAA10.94358691
48ILK0.90769884
49PDGFRB0.90211936
50STK390.90204499
51DAPK30.86228619
52MAP3K140.85971251
53KIT0.85159547
54FES0.85081271
55MKNK20.84704407
56ADRBK20.84339629
57PRKD10.83417897
58TRIB30.82744898
59MAP2K70.81108141
60WNK30.79027387
61FGFR20.77495594
62MET0.70280947
63PLK20.70138434
64LMTK20.69585439
65BCR0.69225481
66TGFBR10.64942222
67LATS20.64170149
68RET0.63161745
69PRKCH0.61307765
70STK40.60961134
71PINK10.60501466
72MAP3K120.59721055
73CDK30.59551488
74NEK90.58244301
75STK110.57677437
76RPS6KA40.56984284
77SGK20.53832672
78STK30.53304744
79MAPK70.52705027
80BMPR20.52489970
81MARK20.51681498
82NTRK20.51137401
83ADRBK10.48989356
84MTOR0.47137564
85ICK0.47100250
86PKN20.46080538
87PRKACG0.46057504
88MAPK40.45959118
89RAF10.45359097
90CAMK40.45210434
91GSK3A0.44858860
92IRAK10.44782342
93RPS6KA50.44177971
94OXSR10.43716623
95CDK60.43066052
96SGK10.42984048
97FGFR10.42696014
98MOS0.42221578
99PRKAA20.40407898
100MAP3K70.40164342
101ERN10.39946493
102EPHA40.39644337
103GRK10.39606658
104MKNK10.38511802
105WNK10.38416641
106PRKD20.38119941
107PRKACB0.37947819
108ABL10.37548008
109MAPK10.36644173
110ROCK20.36604475
111PTK60.36262335
112PRKACA0.36194227
113TYRO30.35918010
114JAK10.35819990
115HIPK20.35806816
116SGK30.35751295
117MAPKAPK50.35656912
118MAPK130.35230190
119SGK4940.35008706
120SGK2230.35008706
121MAP2K10.34966644
122SIK10.34550562
123ABL20.34225123
124CDK90.33730728
125NEK60.33715858
126PIK3CA0.32227049
127CAMK1D0.31858606
128DAPK20.31835141
129INSRR0.31624116
130INSR0.31195589
131PRKG10.30340651
132CAMK10.28364758
133TRPM70.27470114
134CAMK2G0.27269069
135PIK3CG0.27018146
136IGF1R0.26962156
137CSK0.26771806
138ERBB20.25752432
139NTRK10.24854760
140CHUK0.22804383

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045123.98492842
2Dorso-ventral axis formation_Homo sapiens_hsa043203.13949667
3Dilated cardiomyopathy_Homo sapiens_hsa054143.09154097
4Focal adhesion_Homo sapiens_hsa045102.79720794
5Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054102.79482698
6Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.56243163
7Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.53997119
8Vascular smooth muscle contraction_Homo sapiens_hsa042702.33378421
9Renin secretion_Homo sapiens_hsa049242.28472189
10Circadian rhythm_Homo sapiens_hsa047102.25730533
11Amoebiasis_Homo sapiens_hsa051462.12588793
12Protein digestion and absorption_Homo sapiens_hsa049742.04845460
13Histidine metabolism_Homo sapiens_hsa003402.01723288
14Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005322.00838926
15AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.97664048
16TGF-beta signaling pathway_Homo sapiens_hsa043501.94881664
17cGMP-PKG signaling pathway_Homo sapiens_hsa040221.78243116
18Nitrogen metabolism_Homo sapiens_hsa009101.77744602
19Glycerolipid metabolism_Homo sapiens_hsa005611.75927053
20Malaria_Homo sapiens_hsa051441.70257688
21Propanoate metabolism_Homo sapiens_hsa006401.70045711
22Complement and coagulation cascades_Homo sapiens_hsa046101.63432157
23alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.57462866
24Small cell lung cancer_Homo sapiens_hsa052221.57083774
25Linoleic acid metabolism_Homo sapiens_hsa005911.56206444
26Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.55605672
27Proteoglycans in cancer_Homo sapiens_hsa052051.52433880
28Regulation of autophagy_Homo sapiens_hsa041401.47055903
29Adipocytokine signaling pathway_Homo sapiens_hsa049201.43384758
30Ovarian steroidogenesis_Homo sapiens_hsa049131.43229321
31Mineral absorption_Homo sapiens_hsa049781.37679300
32PI3K-Akt signaling pathway_Homo sapiens_hsa041511.35425685
33cAMP signaling pathway_Homo sapiens_hsa040241.34028742
34beta-Alanine metabolism_Homo sapiens_hsa004101.33088996
35Axon guidance_Homo sapiens_hsa043601.32057214
36Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.27807240
37Phenylalanine metabolism_Homo sapiens_hsa003601.26874903
38Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.20579848
39Adherens junction_Homo sapiens_hsa045201.18402972
40Hedgehog signaling pathway_Homo sapiens_hsa043401.18388804
41Viral myocarditis_Homo sapiens_hsa054161.17615729
42Basal cell carcinoma_Homo sapiens_hsa052171.15929085
43Retinol metabolism_Homo sapiens_hsa008301.15347900
44Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.13975442
45Leukocyte transendothelial migration_Homo sapiens_hsa046701.13925249
46Fatty acid biosynthesis_Homo sapiens_hsa000611.12856549
47Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.12692315
48Platelet activation_Homo sapiens_hsa046111.11218195
49Pathways in cancer_Homo sapiens_hsa052001.09331336
50Regulation of actin cytoskeleton_Homo sapiens_hsa048101.08325063
51Gap junction_Homo sapiens_hsa045401.08290312
52Melanoma_Homo sapiens_hsa052181.06133147
53Butanoate metabolism_Homo sapiens_hsa006501.05768976
54African trypanosomiasis_Homo sapiens_hsa051431.05507486
55Rap1 signaling pathway_Homo sapiens_hsa040151.05333475
56Ether lipid metabolism_Homo sapiens_hsa005651.03714207
57Hippo signaling pathway_Homo sapiens_hsa043901.03466571
58Arachidonic acid metabolism_Homo sapiens_hsa005901.02689513
59Rheumatoid arthritis_Homo sapiens_hsa053231.02061361
60AMPK signaling pathway_Homo sapiens_hsa041521.01609648
61Primary bile acid biosynthesis_Homo sapiens_hsa001201.00282655
62Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.98099381
63Oxytocin signaling pathway_Homo sapiens_hsa049210.97732688
64Salivary secretion_Homo sapiens_hsa049700.94965395
65Fat digestion and absorption_Homo sapiens_hsa049750.94927010
66Tyrosine metabolism_Homo sapiens_hsa003500.94099857
67Calcium signaling pathway_Homo sapiens_hsa040200.93878520
68Olfactory transduction_Homo sapiens_hsa047400.93305559
69Tight junction_Homo sapiens_hsa045300.90903177
70Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.89977786
71Morphine addiction_Homo sapiens_hsa050320.89612878
72Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.85275822
73FoxO signaling pathway_Homo sapiens_hsa040680.82643382
74Circadian entrainment_Homo sapiens_hsa047130.80257284
75Thyroid hormone synthesis_Homo sapiens_hsa049180.79055602
76Ras signaling pathway_Homo sapiens_hsa040140.78366462
77Phototransduction_Homo sapiens_hsa047440.77400500
78Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.77317110
79Steroid hormone biosynthesis_Homo sapiens_hsa001400.76673698
80Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.76082511
81Vitamin digestion and absorption_Homo sapiens_hsa049770.74353601
82Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.73971125
83Chemical carcinogenesis_Homo sapiens_hsa052040.73238083
84Estrogen signaling pathway_Homo sapiens_hsa049150.72531194
85Prostate cancer_Homo sapiens_hsa052150.71701578
86Aldosterone synthesis and secretion_Homo sapiens_hsa049250.70300591
87Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.69323324
88Longevity regulating pathway - mammal_Homo sapiens_hsa042110.67609899
89Renin-angiotensin system_Homo sapiens_hsa046140.63912455
90PPAR signaling pathway_Homo sapiens_hsa033200.63300363
91Staphylococcus aureus infection_Homo sapiens_hsa051500.62419110
92Glycerophospholipid metabolism_Homo sapiens_hsa005640.60176927
93MicroRNAs in cancer_Homo sapiens_hsa052060.60005328
94Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.58766839
95TNF signaling pathway_Homo sapiens_hsa046680.57387183
96Bladder cancer_Homo sapiens_hsa052190.56373243
97Wnt signaling pathway_Homo sapiens_hsa043100.55550271
98Notch signaling pathway_Homo sapiens_hsa043300.54957428
99Fatty acid metabolism_Homo sapiens_hsa012120.54611858
100MAPK signaling pathway_Homo sapiens_hsa040100.53774089
101Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.53261769
102Gastric acid secretion_Homo sapiens_hsa049710.53140904
103Fatty acid degradation_Homo sapiens_hsa000710.52858681
104Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.51323509
105Melanogenesis_Homo sapiens_hsa049160.50467261
106Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.49880816
107Insulin secretion_Homo sapiens_hsa049110.49644476
108Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.48916211
109Taste transduction_Homo sapiens_hsa047420.48589142
110Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.47264012
111Lysine degradation_Homo sapiens_hsa003100.47236518
112Toxoplasmosis_Homo sapiens_hsa051450.47134919
113Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.45693289
114Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.45554321
115Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.45274929
116Sulfur relay system_Homo sapiens_hsa041220.44371846
117Serotonergic synapse_Homo sapiens_hsa047260.43372909
118Insulin resistance_Homo sapiens_hsa049310.42938898
119Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.41587315
120Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.40580469
121Tryptophan metabolism_Homo sapiens_hsa003800.40385918
122Arginine and proline metabolism_Homo sapiens_hsa003300.39356052
123Glutamatergic synapse_Homo sapiens_hsa047240.38450344
124Pancreatic cancer_Homo sapiens_hsa052120.38186955
125Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.37973134
126Cholinergic synapse_Homo sapiens_hsa047250.37142107
127Glioma_Homo sapiens_hsa052140.36567463
128Glycosaminoglycan degradation_Homo sapiens_hsa005310.36467049
129Glutathione metabolism_Homo sapiens_hsa004800.36448532
130ABC transporters_Homo sapiens_hsa020100.36416105
131Transcriptional misregulation in cancer_Homo sapiens_hsa052020.35945982
132Pertussis_Homo sapiens_hsa051330.35456688
133Starch and sucrose metabolism_Homo sapiens_hsa005000.35197528
134Bile secretion_Homo sapiens_hsa049760.34941158
135Phospholipase D signaling pathway_Homo sapiens_hsa040720.34643561
136GABAergic synapse_Homo sapiens_hsa047270.34034405

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