

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of oxidative phosphorylation (GO:0002082) | 5.11908737 |
| 2 | ribosomal small subunit biogenesis (GO:0042274) | 4.95894628 |
| 3 | chaperone-mediated protein transport (GO:0072321) | 4.73144273 |
| 4 | cellular response to zinc ion (GO:0071294) | 4.71357498 |
| 5 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.71075373 |
| 6 | rRNA modification (GO:0000154) | 4.53140500 |
| 7 | rRNA methylation (GO:0031167) | 4.40103063 |
| 8 | negative regulation of hydrogen peroxide-induced cell death (GO:1903206) | 4.36851302 |
| 9 | regulation of cellular respiration (GO:0043457) | 4.29202162 |
| 10 | ribosomal large subunit biogenesis (GO:0042273) | 4.27327689 |
| 11 | AMP metabolic process (GO:0046033) | 4.17478326 |
| 12 | ribosome assembly (GO:0042255) | 4.14589972 |
| 13 | negative regulation of response to reactive oxygen species (GO:1901032) | 3.93844376 |
| 14 | ATP synthesis coupled proton transport (GO:0015986) | 3.90681080 |
| 15 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.90681080 |
| 16 | nucleobase-containing small molecule interconversion (GO:0015949) | 3.81681557 |
| 17 | proteasome assembly (GO:0043248) | 3.78831229 |
| 18 | protein targeting to ER (GO:0045047) | 3.77889181 |
| 19 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.76105670 |
| 20 | protein localization to endoplasmic reticulum (GO:0070972) | 3.72233132 |
| 21 | cotranslational protein targeting to membrane (GO:0006613) | 3.71078163 |
| 22 | regulation of hydrogen peroxide-induced cell death (GO:1903205) | 3.69977876 |
| 23 | ADP metabolic process (GO:0046031) | 3.68500443 |
| 24 | viral transcription (GO:0019083) | 3.66277744 |
| 25 | protein targeting to mitochondrion (GO:0006626) | 3.65766247 |
| 26 | positive regulation of catecholamine secretion (GO:0033605) | 3.63965539 |
| 27 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.63176493 |
| 28 | translational termination (GO:0006415) | 3.54053609 |
| 29 | translation (GO:0006412) | 3.51964695 |
| 30 | cullin deneddylation (GO:0010388) | 3.51905083 |
| 31 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.48148192 |
| 32 | DNA double-strand break processing (GO:0000729) | 3.47892952 |
| 33 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.43959422 |
| 34 | protein maturation by protein folding (GO:0022417) | 3.41025342 |
| 35 | glutathione derivative metabolic process (GO:1901685) | 3.38291373 |
| 36 | glutathione derivative biosynthetic process (GO:1901687) | 3.38291373 |
| 37 | respiratory electron transport chain (GO:0022904) | 3.34975162 |
| 38 | translational elongation (GO:0006414) | 3.34257469 |
| 39 | binding of sperm to zona pellucida (GO:0007339) | 3.33038815 |
| 40 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.32598452 |
| 41 | pteridine-containing compound biosynthetic process (GO:0042559) | 3.30875789 |
| 42 | electron transport chain (GO:0022900) | 3.29054589 |
| 43 | sperm motility (GO:0030317) | 3.26336832 |
| 44 | protein deneddylation (GO:0000338) | 3.23852396 |
| 45 | ribosomal small subunit assembly (GO:0000028) | 3.23766940 |
| 46 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.21985609 |
| 47 | activation of protein kinase B activity (GO:0032148) | 3.21109929 |
| 48 | histone exchange (GO:0043486) | 3.20936441 |
| 49 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.19734154 |
| 50 | negative regulation of ligase activity (GO:0051352) | 3.15749238 |
| 51 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.15749238 |
| 52 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.15285635 |
| 53 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.14051692 |
| 54 | cellular component biogenesis (GO:0044085) | 3.11958576 |
| 55 | establishment of protein localization to mitochondrion (GO:0072655) | 3.09284264 |
| 56 | protein localization to mitochondrion (GO:0070585) | 3.09225929 |
| 57 | CENP-A containing nucleosome assembly (GO:0034080) | 3.07308342 |
| 58 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.05813332 |
| 59 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.04306426 |
| 60 | GTP biosynthetic process (GO:0006183) | 3.03597568 |
| 61 | regulation of oxidative stress-induced neuron death (GO:1903203) | 3.03515930 |
| 62 | translational initiation (GO:0006413) | 3.03047159 |
| 63 | positive regulation of ligase activity (GO:0051351) | 3.02530376 |
| 64 | peptidyl-histidine modification (GO:0018202) | 3.00867633 |
| 65 | viral life cycle (GO:0019058) | 2.98402929 |
| 66 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 2.97995320 |
| 67 | IMP metabolic process (GO:0046040) | 2.97578555 |
| 68 | L-phenylalanine metabolic process (GO:0006558) | 2.96831967 |
| 69 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 2.96831967 |
| 70 | chromatin remodeling at centromere (GO:0031055) | 2.96797410 |
| 71 | coenzyme catabolic process (GO:0009109) | 2.91651817 |
| 72 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.91249624 |
| 73 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.90726720 |
| 74 | spliceosomal snRNP assembly (GO:0000387) | 2.90062918 |
| 75 | protein complex biogenesis (GO:0070271) | 2.89559000 |
| 76 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 2.88636257 |
| 77 | L-phenylalanine catabolic process (GO:0006559) | 2.88636257 |
| 78 | single fertilization (GO:0007338) | 2.87352720 |
| 79 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.85183146 |
| 80 | nucleoside salvage (GO:0043174) | 2.84251206 |
| 81 | regulation of ligase activity (GO:0051340) | 2.82018170 |
| 82 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.81574591 |
| 83 | nucleoside diphosphate phosphorylation (GO:0006165) | 2.80244707 |
| 84 | respiratory chain complex IV assembly (GO:0008535) | 2.79730740 |
| 85 | regulation of autophagic vacuole assembly (GO:2000785) | 2.76763457 |
| 86 | rRNA processing (GO:0006364) | 2.75372630 |
| 87 | cellular protein complex disassembly (GO:0043624) | 2.75166861 |
| 88 | purine nucleoside monophosphate biosynthetic process (GO:0009127) | 2.74983742 |
| 89 | purine ribonucleoside monophosphate biosynthetic process (GO:0009168) | 2.74983742 |
| 90 | peroxisome fission (GO:0016559) | 2.74740674 |
| 91 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.73876221 |
| 92 | IMP biosynthetic process (GO:0006188) | 2.70282182 |
| 93 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.69825349 |
| 94 | UTP biosynthetic process (GO:0006228) | 2.69091367 |
| 95 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.69014587 |
| 96 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.69014587 |
| 97 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.69014587 |
| 98 | oxidative phosphorylation (GO:0006119) | 2.68970465 |
| 99 | NADH dehydrogenase complex assembly (GO:0010257) | 2.67850934 |
| 100 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.67850934 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 6.87113113 |
| 2 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 5.18812816 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.01147579 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.47434917 |
| 5 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 4.04979901 |
| 6 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.85335172 |
| 7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.69522200 |
| 8 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 3.41167325 |
| 9 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.23701448 |
| 10 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.97557681 |
| 11 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.78569078 |
| 12 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.77704008 |
| 13 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.66827039 |
| 14 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.65657709 |
| 15 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.63195149 |
| 16 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.54973251 |
| 17 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.44351825 |
| 18 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.31931750 |
| 19 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.28045544 |
| 20 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.25669961 |
| 21 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.19279106 |
| 22 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.18905496 |
| 23 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.16695295 |
| 24 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.12395720 |
| 25 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.07370142 |
| 26 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.05274449 |
| 27 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.05141832 |
| 28 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.97174678 |
| 29 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.88100139 |
| 30 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.86523980 |
| 31 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.82577742 |
| 32 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.81598460 |
| 33 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.81465702 |
| 34 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.81006522 |
| 35 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.80479632 |
| 36 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.74723849 |
| 37 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.70390684 |
| 38 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.68958930 |
| 39 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.56776230 |
| 40 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.53423930 |
| 41 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.49794921 |
| 42 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.41590259 |
| 43 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.40189967 |
| 44 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.39325946 |
| 45 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.38365983 |
| 46 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.37464642 |
| 47 | ELF5_23300383_ChIP-Seq_T47D_Human | 1.35509940 |
| 48 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.34132233 |
| 49 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.32869463 |
| 50 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.32543236 |
| 51 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.32190294 |
| 52 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.32037421 |
| 53 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.29242505 |
| 54 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.28161577 |
| 55 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.24280331 |
| 56 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.20776430 |
| 57 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.14614444 |
| 58 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.14475458 |
| 59 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.14137397 |
| 60 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.13686163 |
| 61 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.12474074 |
| 62 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.11306097 |
| 63 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.09441527 |
| 64 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.08952904 |
| 65 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.07214125 |
| 66 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.07042013 |
| 67 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.06901030 |
| 68 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.06715574 |
| 69 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.06519658 |
| 70 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.05776909 |
| 71 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.03276091 |
| 72 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.02558756 |
| 73 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.01839592 |
| 74 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 1.01169531 |
| 75 | MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 0.99425909 |
| 76 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.99352874 |
| 77 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.98499697 |
| 78 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.97597846 |
| 79 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.94498116 |
| 80 | FUS_26573619_Chip-Seq_HEK293_Human | 0.93576704 |
| 81 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 0.93168637 |
| 82 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.87822973 |
| 83 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 0.87111609 |
| 84 | CHD1_26751641_Chip-Seq_LNCaP_Human | 0.83456624 |
| 85 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 0.82868547 |
| 86 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.79967526 |
| 87 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.79881071 |
| 88 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.79613880 |
| 89 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.78022909 |
| 90 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.75585401 |
| 91 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.74123730 |
| 92 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 0.73833119 |
| 93 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.72683373 |
| 94 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.72274598 |
| 95 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.72152899 |
| 96 | TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse | 0.71201408 |
| 97 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.71062709 |
| 98 | GATA4_21415370_ChIP-Seq_HL-1_Mouse | 0.70531181 |
| 99 | ERA_21632823_ChIP-Seq_H3396_Human | 0.67706744 |
| 100 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 0.67428953 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003806_abnormal_nucleotide_metabolis | 6.70941041 |
| 2 | MP0005410_abnormal_fertilization | 3.56491748 |
| 3 | MP0006036_abnormal_mitochondrial_physio | 3.40800756 |
| 4 | MP0000749_muscle_degeneration | 3.19093644 |
| 5 | MP0009697_abnormal_copulation | 2.91271286 |
| 6 | MP0003315_abnormal_perineum_morphology | 2.74071451 |
| 7 | MP0002132_abnormal_respiratory_system | 2.68496216 |
| 8 | MP0002837_dystrophic_cardiac_calcinosis | 2.62530356 |
| 9 | MP0003718_maternal_effect | 2.55671239 |
| 10 | MP0010234_abnormal_vibrissa_follicle | 2.33959382 |
| 11 | MP0003186_abnormal_redox_activity | 2.31237262 |
| 12 | MP0002160_abnormal_reproductive_system | 2.29435176 |
| 13 | MP0004957_abnormal_blastocyst_morpholog | 2.29064417 |
| 14 | MP0006072_abnormal_retinal_apoptosis | 2.20136332 |
| 15 | MP0008058_abnormal_DNA_repair | 2.11054455 |
| 16 | MP0003693_abnormal_embryo_hatching | 2.10240546 |
| 17 | MP0005058_abnormal_lysosome_morphology | 2.08298150 |
| 18 | MP0000372_irregular_coat_pigmentation | 2.03397608 |
| 19 | MP0003077_abnormal_cell_cycle | 2.00142414 |
| 20 | MP0010094_abnormal_chromosome_stability | 1.98294652 |
| 21 | MP0010386_abnormal_urinary_bladder | 1.93307275 |
| 22 | MP0009780_abnormal_chondrocyte_physiolo | 1.88652991 |
| 23 | MP0005330_cardiomyopathy | 1.87041805 |
| 24 | MP0008007_abnormal_cellular_replicative | 1.82516644 |
| 25 | MP0002090_abnormal_vision | 1.78219209 |
| 26 | MP0008932_abnormal_embryonic_tissue | 1.63456237 |
| 27 | MP0003950_abnormal_plasma_membrane | 1.58378104 |
| 28 | MP0002108_abnormal_muscle_morphology | 1.54646386 |
| 29 | MP0003786_premature_aging | 1.53645901 |
| 30 | MP0002295_abnormal_pulmonary_circulatio | 1.43351379 |
| 31 | MP0001929_abnormal_gametogenesis | 1.40585807 |
| 32 | MP0003136_yellow_coat_color | 1.37787305 |
| 33 | MP0008004_abnormal_stomach_pH | 1.35082476 |
| 34 | MP0000538_abnormal_urinary_bladder | 1.34055309 |
| 35 | MP0003111_abnormal_nucleus_morphology | 1.33952653 |
| 36 | MP0010368_abnormal_lymphatic_system | 1.32989267 |
| 37 | MP0004272_abnormal_basement_membrane | 1.31225251 |
| 38 | MP0001849_ear_inflammation | 1.30935370 |
| 39 | MP0002877_abnormal_melanocyte_morpholog | 1.24677693 |
| 40 | MP0000678_abnormal_parathyroid_gland | 1.24201590 |
| 41 | MP0005187_abnormal_penis_morphology | 1.23507947 |
| 42 | MP0001905_abnormal_dopamine_level | 1.23324960 |
| 43 | MP0003698_abnormal_male_reproductive | 1.23050015 |
| 44 | MP0005408_hypopigmentation | 1.22313326 |
| 45 | MP0005266_abnormal_metabolism | 1.18862302 |
| 46 | MP0003705_abnormal_hypodermis_morpholog | 1.17971392 |
| 47 | MP0005395_other_phenotype | 1.17503366 |
| 48 | MP0009250_abnormal_appendicular_skeleto | 1.17272918 |
| 49 | MP0000762_abnormal_tongue_morphology | 1.17032918 |
| 50 | MP0005332_abnormal_amino_acid | 1.16211606 |
| 51 | MP0004215_abnormal_myocardial_fiber | 1.13678531 |
| 52 | MP0004084_abnormal_cardiac_muscle | 1.13288646 |
| 53 | MP0008438_abnormal_cutaneous_collagen | 1.12990956 |
| 54 | MP0008789_abnormal_olfactory_epithelium | 1.09116470 |
| 55 | MP0000759_abnormal_skeletal_muscle | 1.08946969 |
| 56 | MP0001764_abnormal_homeostasis | 1.08493866 |
| 57 | MP0000343_altered_response_to | 1.07883558 |
| 58 | MP0000537_abnormal_urethra_morphology | 1.06611841 |
| 59 | MP0002210_abnormal_sex_determination | 1.04440902 |
| 60 | MP0004036_abnormal_muscle_relaxation | 1.03424987 |
| 61 | MP0005389_reproductive_system_phenotype | 1.01365231 |
| 62 | MP0005503_abnormal_tendon_morphology | 0.98289254 |
| 63 | MP0001664_abnormal_digestion | 0.97531175 |
| 64 | MP0000653_abnormal_sex_gland | 0.95115604 |
| 65 | MP0010030_abnormal_orbit_morphology | 0.94820493 |
| 66 | MP0000750_abnormal_muscle_regeneration | 0.94695692 |
| 67 | MP0001145_abnormal_male_reproductive | 0.94058346 |
| 68 | MP0002269_muscular_atrophy | 0.93767030 |
| 69 | MP0000733_abnormal_muscle_development | 0.92228678 |
| 70 | MP0005360_urolithiasis | 0.91669008 |
| 71 | MP0001730_embryonic_growth_arrest | 0.89189492 |
| 72 | MP0002163_abnormal_gland_morphology | 0.88806349 |
| 73 | MP0002938_white_spotting | 0.87010090 |
| 74 | MP0005257_abnormal_intraocular_pressure | 0.86486941 |
| 75 | MP0003385_abnormal_body_wall | 0.86287210 |
| 76 | MP0005379_endocrine/exocrine_gland_phen | 0.85353965 |
| 77 | MP0005253_abnormal_eye_physiology | 0.83364194 |
| 78 | MP0000747_muscle_weakness | 0.83170890 |
| 79 | MP0001661_extended_life_span | 0.82329314 |
| 80 | MP0001756_abnormal_urination | 0.82137385 |
| 81 | MP0001881_abnormal_mammary_gland | 0.81910793 |
| 82 | MP0001529_abnormal_vocalization | 0.81606375 |
| 83 | MP0004087_abnormal_muscle_fiber | 0.80336300 |
| 84 | MP0002127_abnormal_cardiovascular_syste | 0.79791093 |
| 85 | MP0005620_abnormal_muscle_contractility | 0.78653479 |
| 86 | MP0004233_abnormal_muscle_weight | 0.73411127 |
| 87 | MP0008057_abnormal_DNA_replication | 0.71515039 |
| 88 | MP0000613_abnormal_salivary_gland | 0.71069455 |
| 89 | MP0001188_hyperpigmentation | 0.70016886 |
| 90 | MP0002161_abnormal_fertility/fecundity | 0.69911760 |
| 91 | MP0005275_abnormal_skin_tensile | 0.68851078 |
| 92 | MP0005647_abnormal_sex_gland | 0.68491286 |
| 93 | MP0002796_impaired_skin_barrier | 0.68205682 |
| 94 | MP0002233_abnormal_nose_morphology | 0.67711468 |
| 95 | MP0005220_abnormal_exocrine_pancreas | 0.67032484 |
| 96 | MP0005165_increased_susceptibility_to | 0.67016640 |
| 97 | MP0003936_abnormal_reproductive_system | 0.66349941 |
| 98 | MP0001853_heart_inflammation | 0.65465263 |
| 99 | MP0000358_abnormal_cell_content/ | 0.64342783 |
| 100 | MP0002080_prenatal_lethality | 0.62025567 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Renal Fanconi syndrome (HP:0001994) | 4.97079547 |
| 2 | Reduced antithrombin III activity (HP:0001976) | 4.47981762 |
| 3 | Resting tremor (HP:0002322) | 4.32111176 |
| 4 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 4.25469782 |
| 5 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 4.25469782 |
| 6 | Lipid accumulation in hepatocytes (HP:0006561) | 4.06149421 |
| 7 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 4.00460602 |
| 8 | Mitochondrial inheritance (HP:0001427) | 3.65541633 |
| 9 | Increased hepatocellular lipid droplets (HP:0006565) | 3.64316141 |
| 10 | Acute necrotizing encephalopathy (HP:0006965) | 3.55407071 |
| 11 | Increased CSF lactate (HP:0002490) | 3.29243164 |
| 12 | Sensory axonal neuropathy (HP:0003390) | 3.27727068 |
| 13 | Acute encephalopathy (HP:0006846) | 3.16100423 |
| 14 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.13687903 |
| 15 | Hepatocellular necrosis (HP:0001404) | 3.12078903 |
| 16 | Macrocytic anemia (HP:0001972) | 2.97419642 |
| 17 | Progressive macrocephaly (HP:0004481) | 2.94434732 |
| 18 | Abnormal protein glycosylation (HP:0012346) | 2.94063800 |
| 19 | Abnormal glycosylation (HP:0012345) | 2.94063800 |
| 20 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.94063800 |
| 21 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.94063800 |
| 22 | Abnormality of renal resorption (HP:0011038) | 2.92132162 |
| 23 | Hepatic necrosis (HP:0002605) | 2.92012269 |
| 24 | Type I transferrin isoform profile (HP:0003642) | 2.90086687 |
| 25 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.72417982 |
| 26 | Rhabdomyolysis (HP:0003201) | 2.69479829 |
| 27 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.68290529 |
| 28 | Abnormality of the intrinsic pathway (HP:0010989) | 2.66674584 |
| 29 | Increased muscle lipid content (HP:0009058) | 2.63421779 |
| 30 | Aplastic anemia (HP:0001915) | 2.56016563 |
| 31 | Hypoplasia of the uterus (HP:0000013) | 2.55760617 |
| 32 | Abnormality of methionine metabolism (HP:0010901) | 2.55480189 |
| 33 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.55357154 |
| 34 | Lactic acidosis (HP:0003128) | 2.48934012 |
| 35 | Respiratory failure (HP:0002878) | 2.44632346 |
| 36 | Increased intramyocellular lipid droplets (HP:0012240) | 2.42590294 |
| 37 | Exertional dyspnea (HP:0002875) | 2.39929270 |
| 38 | Conjunctival hamartoma (HP:0100780) | 2.38947083 |
| 39 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.38882369 |
| 40 | Cerebral edema (HP:0002181) | 2.38630959 |
| 41 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.36680733 |
| 42 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.35317514 |
| 43 | Increased serum lactate (HP:0002151) | 2.35218514 |
| 44 | Aplasia/Hypoplasia of the frontal sinuses (HP:0009119) | 2.32327135 |
| 45 | Abnormality of placental membranes (HP:0011409) | 2.31974509 |
| 46 | Amniotic constriction ring (HP:0009775) | 2.31974509 |
| 47 | Exercise intolerance (HP:0003546) | 2.31399979 |
| 48 | Hypophosphatemic rickets (HP:0004912) | 2.27712379 |
| 49 | Sex reversal (HP:0012245) | 2.25901849 |
| 50 | Abnormal sex determination (HP:0012244) | 2.25901849 |
| 51 | Generalized aminoaciduria (HP:0002909) | 2.25547454 |
| 52 | Abnormality of the frontal sinuses (HP:0002687) | 2.22857195 |
| 53 | 3-Methylglutaconic aciduria (HP:0003535) | 2.22396424 |
| 54 | Cerebral hypomyelination (HP:0006808) | 2.20038184 |
| 55 | Exercise-induced muscle cramps (HP:0003710) | 2.18382279 |
| 56 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.17329796 |
| 57 | Abnormal number of erythroid precursors (HP:0012131) | 2.16489679 |
| 58 | Respiratory difficulties (HP:0002880) | 2.15509071 |
| 59 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.15012936 |
| 60 | Abnormality of the shoulder girdle musculature (HP:0001435) | 2.13958545 |
| 61 | Spinal rigidity (HP:0003306) | 2.13331873 |
| 62 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.10915575 |
| 63 | Generalized amyotrophy (HP:0003700) | 2.03830567 |
| 64 | CNS demyelination (HP:0007305) | 2.03124289 |
| 65 | Abnormality of the ileum (HP:0001549) | 2.01226342 |
| 66 | Abnormality of the preputium (HP:0100587) | 1.99775679 |
| 67 | Meckel diverticulum (HP:0002245) | 1.98419820 |
| 68 | Abnormality of the fetal cardiovascular system (HP:0010948) | 1.98265414 |
| 69 | Abnormal umbilical cord blood vessels (HP:0011403) | 1.98265414 |
| 70 | Single umbilical artery (HP:0001195) | 1.98265414 |
| 71 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 1.97756918 |
| 72 | Male pseudohermaphroditism (HP:0000037) | 1.97585094 |
| 73 | Absent thumb (HP:0009777) | 1.95799710 |
| 74 | Ileus (HP:0002595) | 1.95434401 |
| 75 | Abnormality of the anterior horn cell (HP:0006802) | 1.93371061 |
| 76 | Degeneration of anterior horn cells (HP:0002398) | 1.93371061 |
| 77 | Sparse eyelashes (HP:0000653) | 1.93120305 |
| 78 | Myoglobinuria (HP:0002913) | 1.92214633 |
| 79 | Right ventricular cardiomyopathy (HP:0011663) | 1.91191509 |
| 80 | Abnormality of abdominal situs (HP:0011620) | 1.89725940 |
| 81 | Abdominal situs inversus (HP:0003363) | 1.89725940 |
| 82 | Congenital ichthyosiform erythroderma (HP:0007431) | 1.87074882 |
| 83 | Abnormality of the umbilical cord (HP:0010881) | 1.86416171 |
| 84 | Hyperammonemia (HP:0001987) | 1.85417385 |
| 85 | Hypergonadotropic hypogonadism (HP:0000815) | 1.84742560 |
| 86 | Abnormalities of placenta or umbilical cord (HP:0001194) | 1.82896095 |
| 87 | Abnormal spermatogenesis (HP:0008669) | 1.82624754 |
| 88 | Scapular winging (HP:0003691) | 1.81897339 |
| 89 | Poor head control (HP:0002421) | 1.81643587 |
| 90 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.80100932 |
| 91 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.79097160 |
| 92 | Rhinitis (HP:0012384) | 1.78693193 |
| 93 | Abnormal ciliary motility (HP:0012262) | 1.78528173 |
| 94 | Paralysis (HP:0003470) | 1.77977561 |
| 95 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.75033975 |
| 96 | Testicular atrophy (HP:0000029) | 1.74965272 |
| 97 | Methylmalonic aciduria (HP:0012120) | 1.74641435 |
| 98 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.74547394 |
| 99 | Dicarboxylic aciduria (HP:0003215) | 1.74547394 |
| 100 | Oral leukoplakia (HP:0002745) | 1.73114922 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | PINK1 | 5.30083991 |
| 2 | NME2 | 3.60401586 |
| 3 | STK16 | 3.55686125 |
| 4 | EIF2AK3 | 3.46670657 |
| 5 | MYLK | 3.25009245 |
| 6 | EIF2AK1 | 3.13968976 |
| 7 | VRK2 | 3.07465765 |
| 8 | BUB1 | 2.89669092 |
| 9 | MARK3 | 2.73137298 |
| 10 | ZAK | 2.68918155 |
| 11 | PBK | 2.35863930 |
| 12 | MST4 | 2.19335356 |
| 13 | ARAF | 2.07404398 |
| 14 | SRPK1 | 2.05857152 |
| 15 | NME1 | 1.87548911 |
| 16 | OBSCN | 1.77488779 |
| 17 | CDK19 | 1.76659355 |
| 18 | BMPR1B | 1.73336836 |
| 19 | PLK4 | 1.70222880 |
| 20 | NEK1 | 1.69096420 |
| 21 | VRK1 | 1.54931620 |
| 22 | TESK1 | 1.51594908 |
| 23 | TLK1 | 1.42526549 |
| 24 | LIMK1 | 1.41034872 |
| 25 | RPS6KB2 | 1.32581047 |
| 26 | PAK4 | 1.32190872 |
| 27 | AKT3 | 1.26963060 |
| 28 | ILK | 1.21832532 |
| 29 | PHKG2 | 1.17957875 |
| 30 | PHKG1 | 1.17957875 |
| 31 | MUSK | 1.17657980 |
| 32 | CSNK1G3 | 1.15096066 |
| 33 | CDC7 | 1.15072310 |
| 34 | MOS | 1.14629456 |
| 35 | TTK | 1.13883193 |
| 36 | CSNK1A1L | 1.13502787 |
| 37 | PRKG2 | 1.05780061 |
| 38 | NEK2 | 1.02934068 |
| 39 | BRAF | 1.02476957 |
| 40 | PLK3 | 1.00772494 |
| 41 | INSRR | 0.99775651 |
| 42 | PAK2 | 0.97115980 |
| 43 | CDK8 | 0.96499468 |
| 44 | BCKDK | 0.92802233 |
| 45 | MAP3K12 | 0.92532726 |
| 46 | GRK1 | 0.91471941 |
| 47 | CSNK1G1 | 0.89832780 |
| 48 | PKN2 | 0.88448967 |
| 49 | CDK3 | 0.87706567 |
| 50 | OXSR1 | 0.86232013 |
| 51 | STK38L | 0.86230085 |
| 52 | BRSK2 | 0.86058980 |
| 53 | AURKB | 0.81191515 |
| 54 | PAK1 | 0.81146456 |
| 55 | TIE1 | 0.80666868 |
| 56 | WEE1 | 0.79005066 |
| 57 | NUAK1 | 0.77945230 |
| 58 | MST1R | 0.75224250 |
| 59 | LATS2 | 0.74868771 |
| 60 | LATS1 | 0.74016787 |
| 61 | AURKA | 0.73646096 |
| 62 | AKT2 | 0.73306049 |
| 63 | PLK1 | 0.72645035 |
| 64 | MAP3K13 | 0.72372385 |
| 65 | MAP3K9 | 0.72259158 |
| 66 | TGFBR1 | 0.69021208 |
| 67 | RPS6KA5 | 0.64689168 |
| 68 | MAP4K2 | 0.63526107 |
| 69 | ABL2 | 0.60904314 |
| 70 | MAPKAPK3 | 0.59828271 |
| 71 | CSNK1G2 | 0.56537623 |
| 72 | CDK9 | 0.55003842 |
| 73 | CDK7 | 0.54428478 |
| 74 | DAPK3 | 0.52769460 |
| 75 | STK38 | 0.47032731 |
| 76 | PLK2 | 0.46592057 |
| 77 | EEF2K | 0.46026835 |
| 78 | CCNB1 | 0.45301189 |
| 79 | RPS6KB1 | 0.44900657 |
| 80 | ADRBK2 | 0.41542359 |
| 81 | WNK4 | 0.40651102 |
| 82 | CDK14 | 0.40007187 |
| 83 | TAF1 | 0.36882353 |
| 84 | PDK2 | 0.35433807 |
| 85 | EIF2AK2 | 0.35346378 |
| 86 | CHEK2 | 0.33913882 |
| 87 | CSNK2A2 | 0.32801904 |
| 88 | SMG1 | 0.30882450 |
| 89 | IRAK3 | 0.30205652 |
| 90 | ATR | 0.29821565 |
| 91 | CAMK2D | 0.29784554 |
| 92 | CLK1 | 0.29781529 |
| 93 | STK4 | 0.29603844 |
| 94 | CSNK2A1 | 0.27779726 |
| 95 | PIM2 | 0.27708896 |
| 96 | ATM | 0.27518566 |
| 97 | GRK5 | 0.27057503 |
| 98 | FRK | 0.26709451 |
| 99 | TRIB3 | 0.24485857 |
| 100 | BRSK1 | 0.24310134 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.20253434 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 3.82877515 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.27647613 |
| 4 | Protein export_Homo sapiens_hsa03060 | 3.05963547 |
| 5 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.02346659 |
| 6 | Parkinsons disease_Homo sapiens_hsa05012 | 2.77592863 |
| 7 | DNA replication_Homo sapiens_hsa03030 | 2.39394065 |
| 8 | Glutathione metabolism_Homo sapiens_hsa00480 | 2.21258205 |
| 9 | Folate biosynthesis_Homo sapiens_hsa00790 | 2.17347226 |
| 10 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.02539679 |
| 11 | Mismatch repair_Homo sapiens_hsa03430 | 1.96382584 |
| 12 | RNA polymerase_Homo sapiens_hsa03020 | 1.96318850 |
| 13 | Huntingtons disease_Homo sapiens_hsa05016 | 1.96307944 |
| 14 | Alzheimers disease_Homo sapiens_hsa05010 | 1.85036511 |
| 15 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.78519244 |
| 16 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.76314892 |
| 17 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.72759681 |
| 18 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.66890059 |
| 19 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.66745047 |
| 20 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.66395207 |
| 21 | Basal transcription factors_Homo sapiens_hsa03022 | 1.60425450 |
| 22 | Homologous recombination_Homo sapiens_hsa03440 | 1.59125429 |
| 23 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.56715397 |
| 24 | RNA transport_Homo sapiens_hsa03013 | 1.55094892 |
| 25 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.45566499 |
| 26 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.40657058 |
| 27 | Base excision repair_Homo sapiens_hsa03410 | 1.39828046 |
| 28 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.37938911 |
| 29 | Purine metabolism_Homo sapiens_hsa00230 | 1.36569742 |
| 30 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.34798193 |
| 31 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.34066179 |
| 32 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.30778027 |
| 33 | Carbon metabolism_Homo sapiens_hsa01200 | 1.26565712 |
| 34 | RNA degradation_Homo sapiens_hsa03018 | 1.26193222 |
| 35 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.23005141 |
| 36 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.18842640 |
| 37 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.14675839 |
| 38 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.14004477 |
| 39 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.12597036 |
| 40 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.11580098 |
| 41 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.10639505 |
| 42 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.10370631 |
| 43 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.09131446 |
| 44 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.07977251 |
| 45 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.07957629 |
| 46 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.07348377 |
| 47 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.06461152 |
| 48 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.04622432 |
| 49 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.03886688 |
| 50 | Spliceosome_Homo sapiens_hsa03040 | 1.02478945 |
| 51 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.01952848 |
| 52 | Sulfur relay system_Homo sapiens_hsa04122 | 0.97844138 |
| 53 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.96624864 |
| 54 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.96143192 |
| 55 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.95125254 |
| 56 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.94080660 |
| 57 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.92542417 |
| 58 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.91106905 |
| 59 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.90395009 |
| 60 | Metabolic pathways_Homo sapiens_hsa01100 | 0.89377778 |
| 61 | Mineral absorption_Homo sapiens_hsa04978 | 0.87337416 |
| 62 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.86826841 |
| 63 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.86323224 |
| 64 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.85809683 |
| 65 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.80606310 |
| 66 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.75504599 |
| 67 | Cell cycle_Homo sapiens_hsa04110 | 0.74951618 |
| 68 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.67611477 |
| 69 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.67153589 |
| 70 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.66723699 |
| 71 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.66450399 |
| 72 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.66429143 |
| 73 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.66160253 |
| 74 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.65995238 |
| 75 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.65805999 |
| 76 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.65784302 |
| 77 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.64557250 |
| 78 | Peroxisome_Homo sapiens_hsa04146 | 0.62531691 |
| 79 | Other glycan degradation_Homo sapiens_hsa00511 | 0.56449782 |
| 80 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.51951513 |
| 81 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.47635908 |
| 82 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.44339162 |
| 83 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.43803620 |
| 84 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.42688601 |
| 85 | Gap junction_Homo sapiens_hsa04540 | 0.36652065 |
| 86 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.35086613 |
| 87 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.32608832 |
| 88 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.32407234 |
| 89 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.30270200 |
| 90 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.30165120 |
| 91 | Retinol metabolism_Homo sapiens_hsa00830 | 0.30121924 |
| 92 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.27664335 |
| 93 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.25416920 |
| 94 | Alcoholism_Homo sapiens_hsa05034 | 0.24835739 |
| 95 | Galactose metabolism_Homo sapiens_hsa00052 | 0.24612156 |
| 96 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.23987696 |
| 97 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.22546707 |
| 98 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.22010359 |
| 99 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.21656379 |
| 100 | Olfactory transduction_Homo sapiens_hsa04740 | 0.21592951 |

