C2CD5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)3.98518884
2regulation of protein glycosylation (GO:0060049)3.76788131
3nuclear pore organization (GO:0006999)3.70309436
4synaptic vesicle maturation (GO:0016188)3.65350525
5establishment of nucleus localization (GO:0040023)3.58503941
6histone H3-K4 trimethylation (GO:0080182)3.47557864
7nucleobase catabolic process (GO:0046113)3.46218441
8regulation of short-term neuronal synaptic plasticity (GO:0048172)3.40847318
9nuclear pore complex assembly (GO:0051292)3.39655523
10negative regulation of translation, ncRNA-mediated (GO:0040033)3.38979129
11regulation of translation, ncRNA-mediated (GO:0045974)3.38979129
12negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.38979129
13positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.31372456
14phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.24091663
15epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.24069491
16regulation of histone H3-K27 methylation (GO:0061085)3.18801187
17ionotropic glutamate receptor signaling pathway (GO:0035235)3.18764912
18pre-miRNA processing (GO:0031054)3.17972428
19mitotic chromosome condensation (GO:0007076)3.16078279
20peptidyl-lysine trimethylation (GO:0018023)3.15457411
21histone H3-K4 methylation (GO:0051568)3.13951433
22microtubule depolymerization (GO:0007019)3.09118159
23regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.05638212
24synaptic transmission, glutamatergic (GO:0035249)2.97889370
25glutamate receptor signaling pathway (GO:0007215)2.96842768
26regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.95658454
27female gamete generation (GO:0007292)2.94724925
28positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.94141237
29neuron cell-cell adhesion (GO:0007158)2.91632938
30positive regulation of dendritic spine morphogenesis (GO:0061003)2.90554108
31mechanosensory behavior (GO:0007638)2.90367650
32cilium or flagellum-dependent cell motility (GO:0001539)2.88270129
33nucleus localization (GO:0051647)2.86870103
34Golgi to endosome transport (GO:0006895)2.86460529
35neuron-neuron synaptic transmission (GO:0007270)2.84140326
36mitotic sister chromatid segregation (GO:0000070)2.83925843
37meiotic chromosome segregation (GO:0045132)2.83280712
38auditory behavior (GO:0031223)2.80512621
39regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.79108628
40response to histamine (GO:0034776)2.78751271
41cytoplasmic mRNA processing body assembly (GO:0033962)2.78205733
42synaptic vesicle docking involved in exocytosis (GO:0016081)2.77992326
43positive regulation of cell cycle checkpoint (GO:1901978)2.77881022
44neural tube formation (GO:0001841)2.77514979
45regulation of DNA endoreduplication (GO:0032875)2.76116095
46histone H3-K9 methylation (GO:0051567)2.74101635
47vocalization behavior (GO:0071625)2.74002686
48G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.73678564
49regulation of glutamate receptor signaling pathway (GO:1900449)2.72540443
50protein K11-linked deubiquitination (GO:0035871)2.70081106
51protein localization to synapse (GO:0035418)2.70057176
52positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145)2.70030555
53synaptic vesicle endocytosis (GO:0048488)2.69700367
54behavioral response to ethanol (GO:0048149)2.68723730
55nerve growth factor signaling pathway (GO:0038180)2.66717448
56regulation of DNA damage checkpoint (GO:2000001)2.66081296
57negative regulation of neurotransmitter transport (GO:0051589)2.65795028
58histone lysine methylation (GO:0034968)2.65576575
59centriole replication (GO:0007099)2.64958596
60regulation of female gonad development (GO:2000194)2.64032227
61centriole assembly (GO:0098534)2.63862609
62righting reflex (GO:0060013)2.63156906
63sister chromatid segregation (GO:0000819)2.62796482
64vesicle transport along microtubule (GO:0047496)2.62302659
65interkinetic nuclear migration (GO:0022027)2.62280651
66neurotransmitter-gated ion channel clustering (GO:0072578)2.60858384
67cerebellar Purkinje cell differentiation (GO:0021702)2.60809373
68negative regulation of hormone metabolic process (GO:0032351)2.60182944
69negative regulation of hormone biosynthetic process (GO:0032353)2.60182944
70negative regulation of DNA recombination (GO:0045910)2.58745951
71presynaptic membrane assembly (GO:0097105)2.57765516
72dendritic spine morphogenesis (GO:0060997)2.54641414
73regulation of ARF protein signal transduction (GO:0032012)2.54021014
74sister chromatid cohesion (GO:0007062)2.53965124
75regulation of NFAT protein import into nucleus (GO:0051532)2.53701398
76negative regulation of DNA-dependent DNA replication (GO:2000104)2.53440342
77regulation of meiosis (GO:0040020)2.52637298
78central nervous system neuron axonogenesis (GO:0021955)2.52273576
79cilium movement (GO:0003341)2.52205045
80piRNA metabolic process (GO:0034587)2.51715764
81olfactory bulb development (GO:0021772)2.51526462
82attachment of spindle microtubules to kinetochore (GO:0008608)2.51149780
83mitotic sister chromatid cohesion (GO:0007064)2.50518244
84protein K6-linked ubiquitination (GO:0085020)2.49251763
85negative regulation of neurotransmitter secretion (GO:0046929)2.48805413
86acrosome assembly (GO:0001675)2.48056292
87microtubule nucleation (GO:0007020)2.45924928
88positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021102.45894097
89mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)2.45894097
90negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.45581610
91striatum development (GO:0021756)2.44902974
92startle response (GO:0001964)2.44431621
93negative regulation of fibroblast apoptotic process (GO:2000270)2.44052094
94pore complex assembly (GO:0046931)2.43934838
95oocyte maturation (GO:0001556)2.43697707
96long-term memory (GO:0007616)2.43178717
97synaptic vesicle exocytosis (GO:0016079)2.42900842
98gamma-aminobutyric acid signaling pathway (GO:0007214)2.42877808
99locomotory exploration behavior (GO:0035641)2.41398753
100positive regulation of neurotransmitter secretion (GO:0001956)2.41323927
101postsynaptic membrane organization (GO:0001941)2.38825523
102monoubiquitinated protein deubiquitination (GO:0035520)2.38681321
103DNA damage induced protein phosphorylation (GO:0006975)2.38329617
104glutamate secretion (GO:0014047)2.37162388
105mitotic metaphase plate congression (GO:0007080)2.35859333
106synapse assembly (GO:0007416)2.35649094
107neurotransmitter secretion (GO:0007269)2.34996315
108protein localization to kinetochore (GO:0034501)2.34594197
109DNA topological change (GO:0006265)2.34416917
110negative regulation of meiosis (GO:0045835)2.34288067
111proline transport (GO:0015824)2.33069878
112regulation of meiosis I (GO:0060631)2.33007268
113regulation of synaptic transmission, glutamatergic (GO:0051966)2.32871101
114regulation of synaptic vesicle transport (GO:1902803)2.32767524
115histone H3-K36 demethylation (GO:0070544)2.32645996
116establishment of protein localization to Golgi (GO:0072600)2.32518268
117regulation of synaptic vesicle exocytosis (GO:2000300)2.32284781
118dendrite morphogenesis (GO:0048813)2.31779365
119maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.31771714
120DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla2.31372170
121negative regulation of circadian rhythm (GO:0042754)2.31298015
122histone methylation (GO:0016571)2.30852240
123centrosome localization (GO:0051642)2.30789251
124regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.30697611
125DNA double-strand break processing (GO:0000729)2.30496457
126neuron recognition (GO:0008038)2.30167372
127presynaptic membrane organization (GO:0097090)2.29666249
128regulation of excitatory postsynaptic membrane potential (GO:0060079)2.29105949
129kinetochore organization (GO:0051383)2.28840043
130positive regulation of neurotransmitter transport (GO:0051590)2.28759324
131regulation of dendritic spine morphogenesis (GO:0061001)2.28287582
132negative regulation of histone methylation (GO:0031061)2.27765473
133positive regulation of granulocyte differentiation (GO:0030854)2.27655072
134regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.27564427
135L-amino acid import (GO:0043092)2.27532801
136histone lysine demethylation (GO:0070076)2.26568837
137histone H2A acetylation (GO:0043968)2.26212860
138regulation of Rac protein signal transduction (GO:0035020)2.25923241
139regulation of postsynaptic membrane potential (GO:0060078)2.25549481
140neuronal ion channel clustering (GO:0045161)2.25296499
141protein targeting to Golgi (GO:0000042)2.25272660
142microtubule anchoring (GO:0034453)2.25221248
143axonal fasciculation (GO:0007413)2.25171163
144DNA methylation (GO:0006306)2.24553813
145DNA alkylation (GO:0006305)2.24553813
146establishment of chromosome localization (GO:0051303)2.23445479
147behavioral fear response (GO:0001662)2.22602553
148behavioral defense response (GO:0002209)2.22602553
149regulation of long-term neuronal synaptic plasticity (GO:0048169)2.22467258
150histone H3-K9 modification (GO:0061647)2.22417734
151neuronal action potential propagation (GO:0019227)2.21950175
152positive regulation of membrane potential (GO:0045838)2.20443974
153kinetochore assembly (GO:0051382)2.19547839
154mRNA splice site selection (GO:0006376)2.18744736
155protein localization to chromosome, centromeric region (GO:0071459)2.18113352
156central nervous system projection neuron axonogenesis (GO:0021952)2.17525840
157regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)2.15971719
158regulation of dopamine uptake involved in synaptic transmission (GO:0051584)2.15971719
159generation of neurons (GO:0048699)2.15847712
160long-term synaptic potentiation (GO:0060291)2.15688191
161regulation of meiotic cell cycle (GO:0051445)2.15309286

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.93042159
2GBX2_23144817_ChIP-Seq_PC3_Human3.75476166
3E2F7_22180533_ChIP-Seq_HELA_Human3.09262064
4FOXM1_23109430_ChIP-Seq_U2OS_Human2.70085287
5RBPJ_22232070_ChIP-Seq_NCS_Mouse2.61734821
6SMARCD1_25818293_ChIP-Seq_ESCs_Mouse2.60007648
7SMAD_19615063_ChIP-ChIP_OVARY_Human2.51278465
8GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.38950540
9MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.21710361
10HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.17740028
11FUS_26573619_Chip-Seq_HEK293_Human2.15634042
12POU3F2_20337985_ChIP-ChIP_501MEL_Human2.13095831
13ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.03672891
14IGF1R_20145208_ChIP-Seq_DFB_Human2.03021871
15BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.01700688
16ZFP57_27257070_Chip-Seq_ESCs_Mouse1.86937283
17TAF15_26573619_Chip-Seq_HEK293_Human1.86384204
18FLI1_27457419_Chip-Seq_LIVER_Mouse1.81106165
19SALL1_21062744_ChIP-ChIP_HESCs_Human1.77823503
20CDX2_19796622_ChIP-Seq_MESCs_Mouse1.74571710
21SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.74408509
22CTBP2_25329375_ChIP-Seq_LNCAP_Human1.73571078
23SMAD4_21799915_ChIP-Seq_A2780_Human1.71572097
24TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.71270913
25REST_21632747_ChIP-Seq_MESCs_Mouse1.70957034
26EWS_26573619_Chip-Seq_HEK293_Human1.68383949
27CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.63897910
28PCGF2_27294783_Chip-Seq_ESCs_Mouse1.60820040
29RARB_27405468_Chip-Seq_BRAIN_Mouse1.59522400
30RNF2_27304074_Chip-Seq_NSC_Mouse1.58693516
31TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.57012817
32P300_19829295_ChIP-Seq_ESCs_Human1.56765933
33STAT3_23295773_ChIP-Seq_U87_Human1.56222370
34CTBP1_25329375_ChIP-Seq_LNCAP_Human1.55774872
35NANOG_18555785_Chip-Seq_ESCs_Mouse1.51502246
36PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.51349548
37JARID2_20064375_ChIP-Seq_MESCs_Mouse1.50835334
38TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.50104135
39ZNF274_21170338_ChIP-Seq_K562_Hela1.47238804
40E2F4_17652178_ChIP-ChIP_JURKAT_Human1.47080926
41E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.47024044
42TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.45915258
43POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.45915258
44TCF4_23295773_ChIP-Seq_U87_Human1.45000289
45BMI1_23680149_ChIP-Seq_NPCS_Mouse1.44920938
46ER_23166858_ChIP-Seq_MCF-7_Human1.44742097
47KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.42950814
48AR_21572438_ChIP-Seq_LNCaP_Human1.41491201
49CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.40330119
50TP63_19390658_ChIP-ChIP_HaCaT_Human1.39315664
51IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.36403128
52CBP_20019798_ChIP-Seq_JUKART_Human1.36403128
53CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.35828886
54WT1_19549856_ChIP-ChIP_CCG9911_Human1.34495538
55MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.33633184
56SUZ12_27294783_Chip-Seq_NPCs_Mouse1.32949942
57P53_22127205_ChIP-Seq_FIBROBLAST_Human1.29827973
58DROSHA_22980978_ChIP-Seq_HELA_Human1.29397978
59AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.29291052
60TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.29196916
61IKZF1_21737484_ChIP-ChIP_HCT116_Human1.27821730
62SMAD3_21741376_ChIP-Seq_EPCs_Human1.27753705
63PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.26803302
64NR3C1_21868756_ChIP-Seq_MCF10A_Human1.25927398
65E2F1_18555785_Chip-Seq_ESCs_Mouse1.25629767
66SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.25497974
67BCAT_22108803_ChIP-Seq_LS180_Human1.25351786
68NFE2_27457419_Chip-Seq_LIVER_Mouse1.24765662
69GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.24237266
70FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.20133059
71STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.19378085
72LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.18306224
73NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.18077203
74REST_18959480_ChIP-ChIP_MESCs_Mouse1.18071550
75EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.17851061
76TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.17693458
77TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.17688926
78AR_25329375_ChIP-Seq_VCAP_Human1.17308176
79P53_22387025_ChIP-Seq_ESCs_Mouse1.17246676
80CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.16357824
81MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.15961333
82FLI1_21867929_ChIP-Seq_TH2_Mouse1.14864575
83TCF4_22108803_ChIP-Seq_LS180_Human1.14357172
84TP53_16413492_ChIP-PET_HCT116_Human1.13247934
85IRF1_19129219_ChIP-ChIP_H3396_Human1.13043324
86STAT3_18555785_Chip-Seq_ESCs_Mouse1.12946611
87CMYC_18555785_Chip-Seq_ESCs_Mouse1.12363310
88SUZ12_18555785_Chip-Seq_ESCs_Mouse1.11904688
89RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.11475422
90TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.10393639
91EZH2_27294783_Chip-Seq_NPCs_Mouse1.10360011
92NMYC_18555785_Chip-Seq_ESCs_Mouse1.09088890
93PIAS1_25552417_ChIP-Seq_VCAP_Human1.08966480
94GATA1_26923725_Chip-Seq_HPCs_Mouse1.08826037
95RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.08425817
96TAL1_26923725_Chip-Seq_HPCs_Mouse1.08111288
97TOP2B_26459242_ChIP-Seq_MCF-7_Human1.08067577
98RNF2_27304074_Chip-Seq_ESCs_Mouse1.08050190
99FOXM1_26456572_ChIP-Seq_MCF-7_Human1.08048142
100EZH2_27304074_Chip-Seq_ESCs_Mouse1.06922260
101LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.06751072
102RUNX2_22187159_ChIP-Seq_PCA_Human1.05043145
103YAP1_20516196_ChIP-Seq_MESCs_Mouse1.04968618
104FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.04900697
105SOX2_21211035_ChIP-Seq_LN229_Gbm1.04684821
106PRDM14_20953172_ChIP-Seq_ESCs_Human1.04661205
107SOX2_18555785_Chip-Seq_ESCs_Mouse1.04512413
108EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.04150557
109P300_18555785_Chip-Seq_ESCs_Mouse1.03511061
110ARNT_22903824_ChIP-Seq_MCF-7_Human1.03506330
111TBX3_20139965_ChIP-Seq_MESCs_Mouse1.03148648
112CIITA_25753668_ChIP-Seq_RAJI_Human1.02720777
113CTNNB1_20460455_ChIP-Seq_HCT116_Human1.02301258
114ZNF217_24962896_ChIP-Seq_MCF-7_Human1.02092065
115STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.01357062
116SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.01341475
117TBX3_20139965_ChIP-Seq_ESCs_Mouse1.01193355
118HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.00867282
119PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.00643183
120CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.00466877
121PCGF2_27294783_Chip-Seq_NPCs_Mouse1.00131708
122SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.99333609
123SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.99100358
124CBX2_27304074_Chip-Seq_ESCs_Mouse0.97591357
125UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.97402486
126OCT4_18555785_Chip-Seq_ESCs_Mouse0.97138094
127CTCF_18555785_Chip-Seq_ESCs_Mouse0.96119976
128TBL1_22424771_ChIP-Seq_293T_Human0.95473890
129OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.95022301
130KDM2B_26808549_Chip-Seq_REH_Human0.94625587
131AR_19668381_ChIP-Seq_PC3_Human0.94549845
132YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.94228547
133SOX9_26525672_Chip-Seq_HEART_Mouse0.93675954

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003787_abnormal_imprinting4.18439507
2MP0004859_abnormal_synaptic_plasticity3.55328690
3MP0003880_abnormal_central_pattern3.44981027
4MP0001188_hyperpigmentation3.17708802
5MP0008877_abnormal_DNA_methylation3.00647843
6MP0006292_abnormal_olfactory_placode2.97177407
7MP0002009_preneoplasia2.63173531
8MP0005646_abnormal_pituitary_gland2.52374992
9MP0003635_abnormal_synaptic_transmissio2.40750197
10MP0005423_abnormal_somatic_nervous2.34640098
11MP0000569_abnormal_digit_pigmentation2.24352611
12MP0009745_abnormal_behavioral_response2.09594660
13MP0002822_catalepsy2.08066153
14MP0010094_abnormal_chromosome_stability2.06558233
15MP0003121_genomic_imprinting2.01746150
16MP0002063_abnormal_learning/memory/cond2.01707506
17MP0001968_abnormal_touch/_nociception1.94886437
18MP0001986_abnormal_taste_sensitivity1.89023660
19MP0004270_analgesia1.88163314
20MP0002572_abnormal_emotion/affect_behav1.87224429
21MP0008057_abnormal_DNA_replication1.80469451
22MP0001177_atelectasis1.79965409
23MP0001486_abnormal_startle_reflex1.79121510
24MP0003111_abnormal_nucleus_morphology1.76992974
25MP0009046_muscle_twitch1.74762542
26MP0002064_seizures1.64143890
27MP0001529_abnormal_vocalization1.58237097
28MP0002102_abnormal_ear_morphology1.58075124
29MP0002734_abnormal_mechanical_nocicepti1.57124232
30MP0001984_abnormal_olfaction1.55796451
31MP0002272_abnormal_nervous_system1.55495874
32MP0002736_abnormal_nociception_after1.53273981
33MP0005645_abnormal_hypothalamus_physiol1.51946072
34MP0006072_abnormal_retinal_apoptosis1.49391507
35MP0002735_abnormal_chemical_nociception1.48381394
36MP0005409_darkened_coat_color1.48198975
37MP0004885_abnormal_endolymph1.45568678
38MP0008058_abnormal_DNA_repair1.42483124
39MP0000015_abnormal_ear_pigmentation1.41085275
40MP0001501_abnormal_sleep_pattern1.40687270
41MP0002067_abnormal_sensory_capabilities1.39563940
42MP0005174_abnormal_tail_pigmentation1.37720517
43MP0005248_abnormal_Harderian_gland1.37639144
44MP0002909_abnormal_adrenal_gland1.30835139
45MP0005394_taste/olfaction_phenotype1.30495176
46MP0005499_abnormal_olfactory_system1.30495176
47MP0003077_abnormal_cell_cycle1.30128399
48MP0001502_abnormal_circadian_rhythm1.30092683
49MP0005187_abnormal_penis_morphology1.29958601
50MP0000631_abnormal_neuroendocrine_gland1.28628347
51MP0003693_abnormal_embryo_hatching1.27271463
52MP0004043_abnormal_pH_regulation1.26565241
53MP0002184_abnormal_innervation1.26473617
54MP0002557_abnormal_social/conspecific_i1.26222667
55MP0010352_gastrointestinal_tract_polyps1.25624079
56MP0005551_abnormal_eye_electrophysiolog1.25426433
57MP0009703_decreased_birth_body1.24982187
58MP0000778_abnormal_nervous_system1.22391072
59MP0004924_abnormal_behavior1.21211465
60MP0005386_behavior/neurological_phenoty1.21211465
61MP0002653_abnormal_ependyma_morphology1.18256097
62MP0003690_abnormal_glial_cell1.17194789
63MP0001970_abnormal_pain_threshold1.15710691
64MP0004147_increased_porphyrin_level1.15576392
65MP0004742_abnormal_vestibular_system1.15429903
66MP0003567_abnormal_fetal_cardiomyocyte1.13744460
67MP0008569_lethality_at_weaning1.10449379
68MP0002733_abnormal_thermal_nociception1.09927620
69MP0001905_abnormal_dopamine_level1.09230382
70MP0003879_abnormal_hair_cell1.07350160
71MP0001929_abnormal_gametogenesis1.04803659
72MP0006276_abnormal_autonomic_nervous1.03829232
73MP0003718_maternal_effect1.03629214
74MP0009672_abnormal_birth_weight0.99568793
75MP0003632_abnormal_nervous_system0.98728616
76MP0002882_abnormal_neuron_morphology0.98572206
77MP0008789_abnormal_olfactory_epithelium0.97877915
78MP0001440_abnormal_grooming_behavior0.96492672
79MP0002233_abnormal_nose_morphology0.96337675
80MP0002210_abnormal_sex_determination0.95284709
81MP0000383_abnormal_hair_follicle0.95277085
82MP0010386_abnormal_urinary_bladder0.94868305
83MP0003943_abnormal_hepatobiliary_system0.94787747
84MP0002877_abnormal_melanocyte_morpholog0.94356215
85MP0002638_abnormal_pupillary_reflex0.94182072
86MP0003763_abnormal_thymus_physiology0.93147032
87MP0002396_abnormal_hematopoietic_system0.92871990
88MP0010678_abnormal_skin_adnexa0.91375765
89MP0005310_abnormal_salivary_gland0.90966656
90MP0002095_abnormal_skin_pigmentation0.90705569
91MP0000955_abnormal_spinal_cord0.90165964
92MP0005253_abnormal_eye_physiology0.89728139
93MP0002152_abnormal_brain_morphology0.89461336
94MP0004811_abnormal_neuron_physiology0.89181306
95MP0001119_abnormal_female_reproductive0.88433819
96MP0002163_abnormal_gland_morphology0.87447450
97MP0005379_endocrine/exocrine_gland_phen0.86919337
98MP0003123_paternal_imprinting0.84651081
99MP0003631_nervous_system_phenotype0.84637260
100MP0000427_abnormal_hair_cycle0.84281856
101MP0000653_abnormal_sex_gland0.83993764
102MP0003698_abnormal_male_reproductive0.82123875
103MP0003699_abnormal_female_reproductive0.82028734
104MP0003221_abnormal_cardiomyocyte_apopto0.81368618
105MP0003119_abnormal_digestive_system0.81171699
106MP0001485_abnormal_pinna_reflex0.80636769
107MP0004197_abnormal_fetal_growth/weight/0.80346464
108MP0003861_abnormal_nervous_system0.80205725
109MP0001963_abnormal_hearing_physiology0.79770336
110MP0008007_abnormal_cellular_replicative0.79625788
111MP0002752_abnormal_somatic_nervous0.78260594
112MP0003633_abnormal_nervous_system0.76655324
113MP0003136_yellow_coat_color0.76120266
114MP0003937_abnormal_limbs/digits/tail_de0.76048994
115MP0004133_heterotaxia0.75850110
116MP0002928_abnormal_bile_duct0.74999573
117MP0002249_abnormal_larynx_morphology0.74567389
118MP0000647_abnormal_sebaceous_gland0.74545689
119MP0002069_abnormal_eating/drinking_beha0.74265507
120MP0001293_anophthalmia0.73634815
121MP0002066_abnormal_motor_capabilities/c0.73018796
122MP0000678_abnormal_parathyroid_gland0.73012092
123MP0002081_perinatal_lethality0.72795115
124MP0003183_abnormal_peptide_metabolism0.72204872
125MP0008995_early_reproductive_senescence0.71659946
126MP0002084_abnormal_developmental_patter0.71408755
127MP0002229_neurodegeneration0.70713831
128MP0004808_abnormal_hematopoietic_stem0.69944132
129MP0003646_muscle_fatigue0.66871676
130MP0004142_abnormal_muscle_tone0.66443974
131MP0003890_abnormal_embryonic-extraembry0.66025970
132MP0003122_maternal_imprinting0.65800810
133MP0002161_abnormal_fertility/fecundity0.64327106
134MP0001145_abnormal_male_reproductive0.64139500

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)4.28199927
2Febrile seizures (HP:0002373)3.91456069
3Chromosomal breakage induced by crosslinking agents (HP:0003221)3.90738527
4Chromsome breakage (HP:0040012)3.89863527
5Papillary thyroid carcinoma (HP:0002895)3.22122393
6Volvulus (HP:0002580)3.08182101
7Hyperventilation (HP:0002883)2.98095686
8Abnormality of the fingertips (HP:0001211)2.93105569
9Hepatoblastoma (HP:0002884)2.89022638
10Epileptic encephalopathy (HP:0200134)2.85699646
11Pancreatic fibrosis (HP:0100732)2.82759359
12Abnormality of the labia minora (HP:0012880)2.80610832
13Abnormal hair whorl (HP:0010721)2.72842710
14Impaired vibration sensation in the lower limbs (HP:0002166)2.70122163
15Focal seizures (HP:0007359)2.69745198
16Lip pit (HP:0100267)2.66098827
17Degeneration of the lateral corticospinal tracts (HP:0002314)2.62026730
18Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.62026730
19Atonic seizures (HP:0010819)2.60933650
20Abnormality of the corticospinal tract (HP:0002492)2.59217896
21Stomach cancer (HP:0012126)2.58232128
22Gait imbalance (HP:0002141)2.44852916
23Protruding tongue (HP:0010808)2.44466731
24Abnormality of midbrain morphology (HP:0002418)2.44039683
25Molar tooth sign on MRI (HP:0002419)2.44039683
26Abnormality of chromosome stability (HP:0003220)2.43823400
27Colon cancer (HP:0003003)2.38878235
28Heterotopia (HP:0002282)2.37483008
29Congenital primary aphakia (HP:0007707)2.36531926
30Birth length less than 3rd percentile (HP:0003561)2.36104997
31Cortical dysplasia (HP:0002539)2.33912251
32Aplasia/Hypoplasia of the uvula (HP:0010293)2.33460708
33Nephrogenic diabetes insipidus (HP:0009806)2.29638509
34Oligodactyly (hands) (HP:0001180)2.28006376
35Medial flaring of the eyebrow (HP:0010747)2.25788938
36Gaze-evoked nystagmus (HP:0000640)2.24245927
37Abnormality of chromosome segregation (HP:0002916)2.23148578
38Abnormality of the preputium (HP:0100587)2.20465135
39Progressive cerebellar ataxia (HP:0002073)2.19059597
40Myelodysplasia (HP:0002863)2.18973031
41Urinary urgency (HP:0000012)2.18913624
42Morphological abnormality of the pyramidal tract (HP:0002062)2.18781574
43Acute lymphatic leukemia (HP:0006721)2.17373318
44Broad-based gait (HP:0002136)2.13642655
45True hermaphroditism (HP:0010459)2.13515906
46Poor coordination (HP:0002370)2.13446181
47Abnormality of DNA repair (HP:0003254)2.13057093
48Congenital stationary night blindness (HP:0007642)2.10074684
49Clubbing of toes (HP:0100760)2.07434533
50Meckel diverticulum (HP:0002245)2.06122643
51Aqueductal stenosis (HP:0002410)2.04932097
52Thickened helices (HP:0000391)2.04101466
53Intestinal atresia (HP:0011100)2.03825040
54Ectopic kidney (HP:0000086)2.01753371
55Generalized hypopigmentation of hair (HP:0011358)2.01693104
56Abnormality of the ileum (HP:0001549)2.00096216
57Prostate neoplasm (HP:0100787)1.99568851
58Biliary tract neoplasm (HP:0100574)1.98113245
59Abnormality of the columella (HP:0009929)1.97544729
60Small intestinal stenosis (HP:0012848)1.96232150
61Duodenal stenosis (HP:0100867)1.96232150
62Glioma (HP:0009733)1.94531398
63Patellar aplasia (HP:0006443)1.93851012
64Absent speech (HP:0001344)1.93605996
65Dysdiadochokinesis (HP:0002075)1.92980345
66Facial hemangioma (HP:0000329)1.91176523
67Termporal pattern (HP:0011008)1.91033157
68Insidious onset (HP:0003587)1.91033157
69Rhabdomyosarcoma (HP:0002859)1.90317160
70Abnormality of the carotid arteries (HP:0005344)1.89903725
71Thyroid carcinoma (HP:0002890)1.88520961
72Abnormal biliary tract morphology (HP:0012440)1.88496649
73Impaired smooth pursuit (HP:0007772)1.88347681
74Excessive salivation (HP:0003781)1.87776246
75Drooling (HP:0002307)1.87776246
76Limb dystonia (HP:0002451)1.87659981
77Amyotrophic lateral sclerosis (HP:0007354)1.86546687
78Astrocytoma (HP:0009592)1.85306746
79Abnormality of the astrocytes (HP:0100707)1.85306746
80Impaired vibratory sensation (HP:0002495)1.84746066
81Fair hair (HP:0002286)1.84293506
82Acute myeloid leukemia (HP:0004808)1.83906208
83Chorioretinal coloboma (HP:0000567)1.83705976
84Nephroblastoma (Wilms tumor) (HP:0002667)1.83073524
85Spastic gait (HP:0002064)1.81824803
86Genital tract atresia (HP:0001827)1.80581740
87Lower limb muscle weakness (HP:0007340)1.78565346
88Papilledema (HP:0001085)1.78452563
89Exotropia (HP:0000577)1.78067502
90Urinary bladder sphincter dysfunction (HP:0002839)1.78008643
91Bony spicule pigmentary retinopathy (HP:0007737)1.77915335
92Pancreatic cysts (HP:0001737)1.77551606
93Neoplasm of striated muscle (HP:0009728)1.74762072
94Genetic anticipation (HP:0003743)1.74701744
95Tubulointerstitial nephritis (HP:0001970)1.74043720
96Shawl scrotum (HP:0000049)1.73292361
97Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.72842362
98Preaxial hand polydactyly (HP:0001177)1.72688565
99Generalized tonic-clonic seizures (HP:0002069)1.72398752
100Visual hallucinations (HP:0002367)1.71292162
101Nephronophthisis (HP:0000090)1.70359307
102Aplasia/Hypoplasia of the patella (HP:0006498)1.70259651
103Sloping forehead (HP:0000340)1.70022193
104Progressive inability to walk (HP:0002505)1.69764019
105Clitoromegaly (HP:0000057)1.69609459
106Transitional cell carcinoma of the bladder (HP:0006740)1.69252166
107Median cleft lip (HP:0000161)1.69231111
108Neoplasm of the small intestine (HP:0100833)1.68833122
109Neoplasm of the oral cavity (HP:0100649)1.68593845
110Retinal dysplasia (HP:0007973)1.68424392
111Lissencephaly (HP:0001339)1.67965238
112Embryonal neoplasm (HP:0002898)1.67660879
113Abnormal rod and cone electroretinograms (HP:0008323)1.66578637
114Absence seizures (HP:0002121)1.66527826
115Embryonal renal neoplasm (HP:0011794)1.66462334
116Aganglionic megacolon (HP:0002251)1.66041648
117Cystic hygroma (HP:0000476)1.65873996
118Dialeptic seizures (HP:0011146)1.65801563
119Hypochromic microcytic anemia (HP:0004840)1.65660183
120Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.65173112
121Bile duct proliferation (HP:0001408)1.64587933
122Abnormal biliary tract physiology (HP:0012439)1.64587933
123Hypsarrhythmia (HP:0002521)1.64019898
124Vaginal atresia (HP:0000148)1.62979589
125Gastroesophageal reflux (HP:0002020)1.62896675
126Deeply set eye (HP:0000490)1.62844796
127Cutaneous finger syndactyly (HP:0010554)1.62588514
128Medulloblastoma (HP:0002885)1.61827930
129Abnormal respiratory motile cilium physiology (HP:0012261)1.61809724
130Hypoplastic labia majora (HP:0000059)1.61776605
131Highly arched eyebrow (HP:0002553)1.61764983
132Abnormal respiratory epithelium morphology (HP:0012253)1.61583043
133Abnormal respiratory motile cilium morphology (HP:0005938)1.61583043
134Gastrointestinal carcinoma (HP:0002672)1.60630761
135Malignant gastrointestinal tract tumors (HP:0006749)1.60630761
136Epileptiform EEG discharges (HP:0011182)1.60624040
137Fetal akinesia sequence (HP:0001989)1.60513338
138Hip dysplasia (HP:0001385)1.60353144
139Cystic liver disease (HP:0006706)1.60030325
140Neoplasm of the adrenal cortex (HP:0100641)1.59766622
141Chronic hepatic failure (HP:0100626)1.59526684
142Astigmatism (HP:0000483)1.59188218
143EEG with generalized epileptiform discharges (HP:0011198)1.58332276
144Bladder carcinoma (HP:0002862)1.58024454
145Truncal obesity (HP:0001956)1.57809552
146Aplasia/Hypoplasia of the sternum (HP:0006714)1.57581078
147Abnormality of ocular smooth pursuit (HP:0000617)1.55234521
148Narrow forehead (HP:0000341)1.54828710
149Widely spaced teeth (HP:0000687)1.53436311
150Abnormal ciliary motility (HP:0012262)1.53430045
151Postaxial foot polydactyly (HP:0001830)1.53241642
152Abnormality of the duodenum (HP:0002246)1.52721862
153Abnormality of the renal collecting system (HP:0004742)1.52364907
154Supernumerary spleens (HP:0009799)1.51773578
155Oligodactyly (HP:0012165)1.50067228

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK33.56566428
2TNIK3.25210704
3EPHA43.15475786
4MAP3K102.73886828
5MAP2K72.72699601
6LATS12.55779758
7CASK2.53968701
8MAP3K42.39081635
9MAP3K62.28184569
10WNK32.27952573
11MAPK132.23635255
12CDC72.09862855
13TAOK32.08431929
14UHMK12.07145380
15BMPR21.93470565
16BCR1.85133761
17BRD41.75069084
18MAP3K91.74989235
19PLK41.71727647
20STK38L1.70697801
21TTK1.68216060
22MKNK11.67839627
23LATS21.58969832
24SGK21.57859245
25STK381.51444181
26ERBB31.51309139
27MAP3K131.49680270
28KSR11.47067189
29CDK31.46684541
30PRPF4B1.41440165
31NTRK21.33703570
32MAP3K121.32688040
33FRK1.32380081
34TAOK11.27611582
35FGFR21.24729554
36EEF2K1.23411864
37PASK1.22940503
38CDK121.21240385
39FES1.18869422
40BRAF1.17511393
41ACVR1B1.16176160
42KSR21.15235011
43CAMK1D1.11963860
44RAF11.11085893
45WNK11.10797772
46PLK21.09293843
47MARK21.09060314
48SRPK11.08447429
49CDK81.08128413
50CHEK21.08113242
51MKNK21.06454214
52PAK61.06379519
53CDK91.04525160
54SGK31.03508598
55AKT31.02038629
56SIK21.02029191
57SIK31.00675691
58NEK20.94980745
59MUSK0.91138369
60MARK10.90270983
61CDK60.89806948
62SGK4940.87903431
63SGK2230.87903431
64RIPK40.86868057
65PRKD20.85963206
66CAMKK10.83142229
67BMPR1B0.81825112
68PAK30.81292466
69ZAK0.81271912
70PLK10.78096490
71DAPK10.76972531
72TRIM280.74269997
73SGK10.71913681
74TXK0.71834294
75MAP2K40.70425718
76TNK20.70263476
77NEK60.69458424
78PRKD30.68566081
79MINK10.66504034
80DYRK20.65125751
81ATM0.64987240
82BRSK10.64669056
83DYRK1B0.64490791
84DYRK1A0.64360041
85OXSR10.64178964
86ATR0.63290863
87STK160.62082136
88CHEK10.60542845
89STK30.59788232
90FGR0.59465879
91PLK30.58728176
92CAMK10.56832378
93MELK0.56694954
94PNCK0.56578064
95CCNB10.54970040
96CAMK1G0.54764371
97PRKDC0.54486900
98MOS0.53201386
99HIPK20.53178014
100TSSK60.52555336
101EIF2AK30.52452839
102FGFR30.51769803
103ERBB20.50838662
104CDK190.50783496
105NEK90.50533401
106YES10.49222303
107WEE10.48792372
108TEC0.48121278
109CDK50.47843473
110PINK10.47701128
111ALK0.46968962
112CSNK1E0.46820952
113CSNK1G10.46149125
114CDK10.46088135
115PRKCE0.45414987
116CSNK1D0.43762206
117MAPK100.43749019
118GSK3B0.43062457
119CSNK1G20.42923561
120DAPK20.42713683
121CDK20.42142351
122STK110.42133215
123DYRK30.41148199
124CAMK2A0.40900374
125BRSK20.40147050
126MAPK140.39326797
127NLK0.38701384
128STK390.38371844
129NUAK10.38366372
130PRKCH0.38243965
131CAMKK20.38242166
132RPS6KB10.37863680
133PRKCG0.37752496
134RET0.37661699
135CAMK40.36280849
136PRKAA10.36259665
137AURKB0.33412013
138VRK10.33340792

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050332.95196426
2Olfactory transduction_Homo sapiens_hsa047402.17931150
3Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.93520910
4Morphine addiction_Homo sapiens_hsa050321.90703568
5Long-term potentiation_Homo sapiens_hsa047201.90372608
6Glutamatergic synapse_Homo sapiens_hsa047241.87612325
7Circadian entrainment_Homo sapiens_hsa047131.84199901
8Phototransduction_Homo sapiens_hsa047441.83510460
9Fanconi anemia pathway_Homo sapiens_hsa034601.76204568
10Taste transduction_Homo sapiens_hsa047421.72454251
11Amphetamine addiction_Homo sapiens_hsa050311.71468648
12Synaptic vesicle cycle_Homo sapiens_hsa047211.64562148
13Non-homologous end-joining_Homo sapiens_hsa034501.52053232
14Dopaminergic synapse_Homo sapiens_hsa047281.51795856
15Serotonergic synapse_Homo sapiens_hsa047261.50029631
16RNA degradation_Homo sapiens_hsa030181.48951270
17GABAergic synapse_Homo sapiens_hsa047271.48896406
18Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.47452427
19Cell cycle_Homo sapiens_hsa041101.42795279
20Long-term depression_Homo sapiens_hsa047301.42529255
21Circadian rhythm_Homo sapiens_hsa047101.38531796
22Phosphatidylinositol signaling system_Homo sapiens_hsa040701.37373498
23Cholinergic synapse_Homo sapiens_hsa047251.35574184
24Insulin secretion_Homo sapiens_hsa049111.35410830
25Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.30431103
26Oocyte meiosis_Homo sapiens_hsa041141.30006862
27Salivary secretion_Homo sapiens_hsa049701.23119611
28Homologous recombination_Homo sapiens_hsa034401.20434102
29Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.19950533
30Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.19539969
31GnRH signaling pathway_Homo sapiens_hsa049121.16702628
32Aldosterone synthesis and secretion_Homo sapiens_hsa049251.16341219
33Calcium signaling pathway_Homo sapiens_hsa040201.13490084
34Oxytocin signaling pathway_Homo sapiens_hsa049211.11418665
35Basal transcription factors_Homo sapiens_hsa030221.11004093
36mRNA surveillance pathway_Homo sapiens_hsa030151.08847971
37ErbB signaling pathway_Homo sapiens_hsa040121.06345971
38Cocaine addiction_Homo sapiens_hsa050301.05970759
39cAMP signaling pathway_Homo sapiens_hsa040241.04876846
40Choline metabolism in cancer_Homo sapiens_hsa052311.03845489
41Maturity onset diabetes of the young_Homo sapiens_hsa049501.03194034
42Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.00977396
43Renin secretion_Homo sapiens_hsa049241.00564903
44Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.00307393
45Lysine degradation_Homo sapiens_hsa003100.97988563
46Mismatch repair_Homo sapiens_hsa034300.97164251
47Adherens junction_Homo sapiens_hsa045200.94685628
48Thyroid hormone signaling pathway_Homo sapiens_hsa049190.93267564
49Colorectal cancer_Homo sapiens_hsa052100.93002783
50Type II diabetes mellitus_Homo sapiens_hsa049300.92079751
51Base excision repair_Homo sapiens_hsa034100.90786148
52Inositol phosphate metabolism_Homo sapiens_hsa005620.89694723
53Thyroid hormone synthesis_Homo sapiens_hsa049180.87431019
54Ovarian steroidogenesis_Homo sapiens_hsa049130.86959128
55Dorso-ventral axis formation_Homo sapiens_hsa043200.85940993
56Glioma_Homo sapiens_hsa052140.85004430
57Non-small cell lung cancer_Homo sapiens_hsa052230.83762928
58Alcoholism_Homo sapiens_hsa050340.83570176
59Gastric acid secretion_Homo sapiens_hsa049710.82748939
60Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.81113057
61Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.80351015
62Estrogen signaling pathway_Homo sapiens_hsa049150.79484126
63Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.79315106
64Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.78924032
65Primary immunodeficiency_Homo sapiens_hsa053400.78723350
66MAPK signaling pathway_Homo sapiens_hsa040100.78135524
67Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.77587325
68Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.77412393
69cGMP-PKG signaling pathway_Homo sapiens_hsa040220.77232758
70Pancreatic cancer_Homo sapiens_hsa052120.76100873
71Endometrial cancer_Homo sapiens_hsa052130.75781144
72Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.74676836
73Gap junction_Homo sapiens_hsa045400.74138436
74Phospholipase D signaling pathway_Homo sapiens_hsa040720.74081433
75Prolactin signaling pathway_Homo sapiens_hsa049170.73954236
76Regulation of autophagy_Homo sapiens_hsa041400.73602546
77Butanoate metabolism_Homo sapiens_hsa006500.73108918
78Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.70399149
79Transcriptional misregulation in cancer_Homo sapiens_hsa052020.70379856
80Propanoate metabolism_Homo sapiens_hsa006400.68901849
81Ras signaling pathway_Homo sapiens_hsa040140.68506722
82Chemokine signaling pathway_Homo sapiens_hsa040620.66098487
83Collecting duct acid secretion_Homo sapiens_hsa049660.65379211
84T cell receptor signaling pathway_Homo sapiens_hsa046600.65038468
85FoxO signaling pathway_Homo sapiens_hsa040680.64798390
86mTOR signaling pathway_Homo sapiens_hsa041500.64578807
87Ether lipid metabolism_Homo sapiens_hsa005650.64378062
88DNA replication_Homo sapiens_hsa030300.64292047
89Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.64272582
90Prostate cancer_Homo sapiens_hsa052150.63567496
91p53 signaling pathway_Homo sapiens_hsa041150.62999451
92Melanogenesis_Homo sapiens_hsa049160.62956924
93Wnt signaling pathway_Homo sapiens_hsa043100.62548898
94Hedgehog signaling pathway_Homo sapiens_hsa043400.61919728
95Renal cell carcinoma_Homo sapiens_hsa052110.61786099
96Axon guidance_Homo sapiens_hsa043600.60793190
97Neurotrophin signaling pathway_Homo sapiens_hsa047220.58790170
98Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.58596513
99Carbohydrate digestion and absorption_Homo sapiens_hsa049730.58438709
100Tight junction_Homo sapiens_hsa045300.58051559
101Nucleotide excision repair_Homo sapiens_hsa034200.56816137
102MicroRNAs in cancer_Homo sapiens_hsa052060.56674029
103B cell receptor signaling pathway_Homo sapiens_hsa046620.56367981
104Vascular smooth muscle contraction_Homo sapiens_hsa042700.56260480
105Chronic myeloid leukemia_Homo sapiens_hsa052200.55841042
106RNA transport_Homo sapiens_hsa030130.55586094
107ABC transporters_Homo sapiens_hsa020100.55232299
108Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.54745247
109Hippo signaling pathway_Homo sapiens_hsa043900.53504179
110VEGF signaling pathway_Homo sapiens_hsa043700.52772173
111Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.52576343
112Glucagon signaling pathway_Homo sapiens_hsa049220.51986674
113Purine metabolism_Homo sapiens_hsa002300.51295206
114Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.51090301
115Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.51031023
116Thyroid cancer_Homo sapiens_hsa052160.50611898
117Fatty acid biosynthesis_Homo sapiens_hsa000610.50017766
118Hepatitis B_Homo sapiens_hsa051610.47645071
119Longevity regulating pathway - mammal_Homo sapiens_hsa042110.46454314
120Pancreatic secretion_Homo sapiens_hsa049720.46302446
121Sphingolipid signaling pathway_Homo sapiens_hsa040710.45809605
122Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.45593224
123Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.44704456
124Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.44596858
125Rap1 signaling pathway_Homo sapiens_hsa040150.44145919
126Acute myeloid leukemia_Homo sapiens_hsa052210.44014182
127Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.43501701

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