

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.87797549 |
| 2 | proteasome assembly (GO:0043248) | 4.75536753 |
| 3 | maturation of SSU-rRNA (GO:0030490) | 4.51151433 |
| 4 | chaperone-mediated protein transport (GO:0072321) | 4.44570233 |
| 5 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.31248496 |
| 6 | ATP synthesis coupled proton transport (GO:0015986) | 4.24117220 |
| 7 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.24117220 |
| 8 | cullin deneddylation (GO:0010388) | 4.19032170 |
| 9 | ribosomal small subunit biogenesis (GO:0042274) | 4.15894893 |
| 10 | establishment of integrated proviral latency (GO:0075713) | 4.08542935 |
| 11 | chromatin remodeling at centromere (GO:0031055) | 4.05363564 |
| 12 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 4.02019757 |
| 13 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.99540687 |
| 14 | ribosomal small subunit assembly (GO:0000028) | 3.98279974 |
| 15 | protein deneddylation (GO:0000338) | 3.97901578 |
| 16 | ribosomal large subunit biogenesis (GO:0042273) | 3.97536149 |
| 17 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.97337691 |
| 18 | CENP-A containing nucleosome assembly (GO:0034080) | 3.96829708 |
| 19 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.96761162 |
| 20 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.95609851 |
| 21 | negative regulation of ligase activity (GO:0051352) | 3.95609851 |
| 22 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.88386755 |
| 23 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.88260566 |
| 24 | regulation of mitochondrial translation (GO:0070129) | 3.81000101 |
| 25 | establishment of viral latency (GO:0019043) | 3.76308884 |
| 26 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.72722132 |
| 27 | formation of translation preinitiation complex (GO:0001731) | 3.61601086 |
| 28 | pseudouridine synthesis (GO:0001522) | 3.59815102 |
| 29 | viral transcription (GO:0019083) | 3.58247040 |
| 30 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.57980335 |
| 31 | termination of RNA polymerase III transcription (GO:0006386) | 3.57980335 |
| 32 | translational termination (GO:0006415) | 3.57777573 |
| 33 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.56352454 |
| 34 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.55708366 |
| 35 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 3.53775529 |
| 36 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.52879397 |
| 37 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.52879397 |
| 38 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.52879397 |
| 39 | respiratory electron transport chain (GO:0022904) | 3.51191061 |
| 40 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.50391255 |
| 41 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.50391255 |
| 42 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.48945704 |
| 43 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.48558672 |
| 44 | purine nucleobase biosynthetic process (GO:0009113) | 3.48277750 |
| 45 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.44446335 |
| 46 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.43353320 |
| 47 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.43353320 |
| 48 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.42421597 |
| 49 | DNA replication checkpoint (GO:0000076) | 3.42238712 |
| 50 | IMP biosynthetic process (GO:0006188) | 3.40507047 |
| 51 | translation (GO:0006412) | 3.39565780 |
| 52 | cotranslational protein targeting to membrane (GO:0006613) | 3.38535134 |
| 53 | protein targeting to mitochondrion (GO:0006626) | 3.38304510 |
| 54 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.38236491 |
| 55 | electron transport chain (GO:0022900) | 3.38030300 |
| 56 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.36912126 |
| 57 | protein targeting to ER (GO:0045047) | 3.34950418 |
| 58 | positive regulation of ligase activity (GO:0051351) | 3.34141289 |
| 59 | rRNA processing (GO:0006364) | 3.33989338 |
| 60 | DNA damage response, detection of DNA damage (GO:0042769) | 3.32330047 |
| 61 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.31234708 |
| 62 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.31234708 |
| 63 | NADH dehydrogenase complex assembly (GO:0010257) | 3.31234708 |
| 64 | protein complex biogenesis (GO:0070271) | 3.31020831 |
| 65 | L-serine metabolic process (GO:0006563) | 3.30878495 |
| 66 | rRNA metabolic process (GO:0016072) | 3.27900545 |
| 67 | translational initiation (GO:0006413) | 3.27338721 |
| 68 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.26496248 |
| 69 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.26496248 |
| 70 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.23874813 |
| 71 | translational elongation (GO:0006414) | 3.22950159 |
| 72 | cellular component biogenesis (GO:0044085) | 3.22893516 |
| 73 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.22195669 |
| 74 | rRNA modification (GO:0000154) | 3.21651685 |
| 75 | protein neddylation (GO:0045116) | 3.21627664 |
| 76 | histone exchange (GO:0043486) | 3.21256548 |
| 77 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.20145623 |
| 78 | oxidative phosphorylation (GO:0006119) | 3.17830898 |
| 79 | protein localization to endoplasmic reticulum (GO:0070972) | 3.17089654 |
| 80 | nucleobase biosynthetic process (GO:0046112) | 3.14005486 |
| 81 | establishment of protein localization to mitochondrion (GO:0072655) | 3.13937900 |
| 82 | spliceosomal snRNP assembly (GO:0000387) | 3.13167564 |
| 83 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 3.13117715 |
| 84 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.12698707 |
| 85 | mitotic metaphase plate congression (GO:0007080) | 3.12628192 |
| 86 | protein localization to mitochondrion (GO:0070585) | 3.08328207 |
| 87 | protein localization to kinetochore (GO:0034501) | 3.07608406 |
| 88 | regulation of ligase activity (GO:0051340) | 3.07444924 |
| 89 | ribosome assembly (GO:0042255) | 3.03732772 |
| 90 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.02493139 |
| 91 | DNA replication-independent nucleosome organization (GO:0034724) | 3.02493139 |
| 92 | DNA deamination (GO:0045006) | 2.98094461 |
| 93 | DNA strand elongation (GO:0022616) | 2.96390867 |
| 94 | IMP metabolic process (GO:0046040) | 2.96367621 |
| 95 | transcription from mitochondrial promoter (GO:0006390) | 2.96051537 |
| 96 | mitochondrial RNA metabolic process (GO:0000959) | 2.94006252 |
| 97 | ribosome biogenesis (GO:0042254) | 2.93640585 |
| 98 | base-excision repair, AP site formation (GO:0006285) | 2.93118306 |
| 99 | viral life cycle (GO:0019058) | 2.92810989 |
| 100 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 2.91139364 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | * KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.13758947 |
| 2 | E2F7_22180533_ChIP-Seq_HELA_Human | 4.94581020 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.26833307 |
| 4 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.19586337 |
| 5 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.72446387 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.66845249 |
| 7 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.51936903 |
| 8 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.42976779 |
| 9 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 3.36079966 |
| 10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.35328343 |
| 11 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.28448677 |
| 12 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.16733751 |
| 13 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 3.12257400 |
| 14 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 3.00214001 |
| 15 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.79344883 |
| 16 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.77322407 |
| 17 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.71795434 |
| 18 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.66925901 |
| 19 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.66744358 |
| 20 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.42768907 |
| 21 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.41780673 |
| 22 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.39383408 |
| 23 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.38953265 |
| 24 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.37880705 |
| 25 | * FOXP3_21729870_ChIP-Seq_TREG_Human | 2.32767763 |
| 26 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.29636921 |
| 27 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.23085919 |
| 28 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.19493430 |
| 29 | * GABP_19822575_ChIP-Seq_HepG2_Human | 2.19081075 |
| 30 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.11396451 |
| 31 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.10696165 |
| 32 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.09524744 |
| 33 | TTF2_22483619_ChIP-Seq_HELA_Human | 2.07128623 |
| 34 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.02991032 |
| 35 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.00750997 |
| 36 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.99608647 |
| 37 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.98964794 |
| 38 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.98957026 |
| 39 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.93709080 |
| 40 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.87703303 |
| 41 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.87404734 |
| 42 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.81662808 |
| 43 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.79376140 |
| 44 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.70152598 |
| 45 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.68940945 |
| 46 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.68731472 |
| 47 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.61312250 |
| 48 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.60987834 |
| 49 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.59651200 |
| 50 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.57498166 |
| 51 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.56913788 |
| 52 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.55305498 |
| 53 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.55059322 |
| 54 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.42727445 |
| 55 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.38953999 |
| 56 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.36664732 |
| 57 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.31733159 |
| 58 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.28495008 |
| 59 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.28048875 |
| 60 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.27369889 |
| 61 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.27170583 |
| 62 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.22160980 |
| 63 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.16904435 |
| 64 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.15968535 |
| 65 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.14799156 |
| 66 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.11576028 |
| 67 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.10264307 |
| 68 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.08297605 |
| 69 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.07453673 |
| 70 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.07256983 |
| 71 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.05811653 |
| 72 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.05547403 |
| 73 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.04937707 |
| 74 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.00539927 |
| 75 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.00128090 |
| 76 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.98740550 |
| 77 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.97806321 |
| 78 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.96622402 |
| 79 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.96448322 |
| 80 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.95942368 |
| 81 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.95178096 |
| 82 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.95018518 |
| 83 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.94837145 |
| 84 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.93667832 |
| 85 | VDR_22108803_ChIP-Seq_LS180_Human | 0.92907008 |
| 86 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.89877402 |
| 87 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.88089554 |
| 88 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.87211449 |
| 89 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.84571141 |
| 90 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.83888838 |
| 91 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.83257106 |
| 92 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.83140577 |
| 93 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.79357504 |
| 94 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.78803216 |
| 95 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.76497248 |
| 96 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.76125460 |
| 97 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.75754045 |
| 98 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.75335297 |
| 99 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.74450397 |
| 100 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.73808231 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003693_abnormal_embryo_hatching | 4.28972797 |
| 2 | MP0008058_abnormal_DNA_repair | 4.15541611 |
| 3 | MP0003806_abnormal_nucleotide_metabolis | 4.10352693 |
| 4 | MP0004957_abnormal_blastocyst_morpholog | 3.58283018 |
| 5 | MP0010094_abnormal_chromosome_stability | 3.48575709 |
| 6 | MP0008007_abnormal_cellular_replicative | 3.12268706 |
| 7 | MP0003111_abnormal_nucleus_morphology | 2.99282161 |
| 8 | MP0003186_abnormal_redox_activity | 2.83421818 |
| 9 | MP0009697_abnormal_copulation | 2.70910572 |
| 10 | MP0003077_abnormal_cell_cycle | 2.69741364 |
| 11 | MP0003786_premature_aging | 2.48658006 |
| 12 | MP0003123_paternal_imprinting | 2.44050925 |
| 13 | MP0003718_maternal_effect | 2.34834111 |
| 14 | MP0008932_abnormal_embryonic_tissue | 2.32840784 |
| 15 | MP0006292_abnormal_olfactory_placode | 2.31500694 |
| 16 | MP0002139_abnormal_hepatobiliary_system | 2.29684291 |
| 17 | MP0006036_abnormal_mitochondrial_physio | 2.25255444 |
| 18 | MP0002163_abnormal_gland_morphology | 2.16962092 |
| 19 | MP0005085_abnormal_gallbladder_physiolo | 2.14172853 |
| 20 | MP0008789_abnormal_olfactory_epithelium | 2.10579147 |
| 21 | MP0008875_abnormal_xenobiotic_pharmacok | 2.07264697 |
| 22 | MP0006035_abnormal_mitochondrial_morpho | 2.04309873 |
| 23 | MP0009379_abnormal_foot_pigmentation | 2.02772943 |
| 24 | MP0001529_abnormal_vocalization | 1.93165461 |
| 25 | MP0001764_abnormal_homeostasis | 1.80706386 |
| 26 | MP0003315_abnormal_perineum_morphology | 1.77187035 |
| 27 | MP0008877_abnormal_DNA_methylation | 1.67915621 |
| 28 | MP0003941_abnormal_skin_development | 1.63428149 |
| 29 | MP0005360_urolithiasis | 1.59706968 |
| 30 | MP0005379_endocrine/exocrine_gland_phen | 1.51325470 |
| 31 | MP0005394_taste/olfaction_phenotype | 1.50495472 |
| 32 | MP0005499_abnormal_olfactory_system | 1.50495472 |
| 33 | MP0006072_abnormal_retinal_apoptosis | 1.46663281 |
| 34 | MP0001730_embryonic_growth_arrest | 1.45442322 |
| 35 | MP0002160_abnormal_reproductive_system | 1.39594440 |
| 36 | MP0002938_white_spotting | 1.39168768 |
| 37 | MP0005365_abnormal_bile_salt | 1.36829012 |
| 38 | MP0003011_delayed_dark_adaptation | 1.36801149 |
| 39 | MP0001293_anophthalmia | 1.31424675 |
| 40 | MP0005332_abnormal_amino_acid | 1.30803619 |
| 41 | MP0003195_calcinosis | 1.26473009 |
| 42 | MP0003890_abnormal_embryonic-extraembry | 1.22276706 |
| 43 | MP0004133_heterotaxia | 1.21818035 |
| 44 | MP0000358_abnormal_cell_content/ | 1.20486499 |
| 45 | MP0002638_abnormal_pupillary_reflex | 1.19431792 |
| 46 | MP0005187_abnormal_penis_morphology | 1.18505686 |
| 47 | MP0002210_abnormal_sex_determination | 1.18505082 |
| 48 | MP0005408_hypopigmentation | 1.17954836 |
| 49 | MP0001697_abnormal_embryo_size | 1.14459987 |
| 50 | MP0000350_abnormal_cell_proliferation | 1.13689511 |
| 51 | MP0003567_abnormal_fetal_cardiomyocyte | 1.12298851 |
| 52 | MP0008057_abnormal_DNA_replication | 1.10543976 |
| 53 | MP0004147_increased_porphyrin_level | 1.07366244 |
| 54 | MP0000313_abnormal_cell_death | 1.06115303 |
| 55 | MP0002736_abnormal_nociception_after | 1.05472217 |
| 56 | MP0003121_genomic_imprinting | 1.03286429 |
| 57 | MP0002102_abnormal_ear_morphology | 1.02736670 |
| 58 | MP0005084_abnormal_gallbladder_morpholo | 1.01377298 |
| 59 | MP0000647_abnormal_sebaceous_gland | 0.99746752 |
| 60 | MP0002138_abnormal_hepatobiliary_system | 0.98126476 |
| 61 | MP0003937_abnormal_limbs/digits/tail_de | 0.97944219 |
| 62 | MP0009672_abnormal_birth_weight | 0.97196515 |
| 63 | MP0005389_reproductive_system_phenotype | 0.96533007 |
| 64 | MP0000372_irregular_coat_pigmentation | 0.96312891 |
| 65 | MP0000653_abnormal_sex_gland | 0.96288454 |
| 66 | MP0000490_abnormal_crypts_of | 0.95230507 |
| 67 | MP0001929_abnormal_gametogenesis | 0.93528655 |
| 68 | MP0001145_abnormal_male_reproductive | 0.93254980 |
| 69 | MP0003252_abnormal_bile_duct | 0.93040008 |
| 70 | MP0010030_abnormal_orbit_morphology | 0.90253600 |
| 71 | MP0002233_abnormal_nose_morphology | 0.89631016 |
| 72 | MP0002080_prenatal_lethality | 0.89297664 |
| 73 | MP0002090_abnormal_vision | 0.88734598 |
| 74 | MP0001881_abnormal_mammary_gland | 0.88567285 |
| 75 | MP0005380_embryogenesis_phenotype | 0.87596009 |
| 76 | MP0001672_abnormal_embryogenesis/_devel | 0.87596009 |
| 77 | MP0001727_abnormal_embryo_implantation | 0.82972851 |
| 78 | MP0002085_abnormal_embryonic_tissue | 0.81240759 |
| 79 | MP0002084_abnormal_developmental_patter | 0.80096046 |
| 80 | MP0001119_abnormal_female_reproductive | 0.78936003 |
| 81 | MP0005266_abnormal_metabolism | 0.78489084 |
| 82 | MP0001666_abnormal_nutrient_absorption | 0.78460969 |
| 83 | MP0002876_abnormal_thyroid_physiology | 0.76751552 |
| 84 | MP0002697_abnormal_eye_size | 0.74946963 |
| 85 | MP0003119_abnormal_digestive_system | 0.74859552 |
| 86 | MP0005636_abnormal_mineral_homeostasis | 0.73716418 |
| 87 | MP0003787_abnormal_imprinting | 0.73350161 |
| 88 | MP0005501_abnormal_skin_physiology | 0.72011998 |
| 89 | MP0003646_muscle_fatigue | 0.71836444 |
| 90 | MP0001188_hyperpigmentation | 0.71724528 |
| 91 | MP0000049_abnormal_middle_ear | 0.71096687 |
| 92 | MP0003868_abnormal_feces_composition | 0.71096397 |
| 93 | MP0010386_abnormal_urinary_bladder | 0.70980661 |
| 94 | MP0001286_abnormal_eye_development | 0.70189896 |
| 95 | MP0005395_other_phenotype | 0.68117731 |
| 96 | MP0001324_abnormal_eye_pigmentation | 0.67057089 |
| 97 | MP0002019_abnormal_tumor_incidence | 0.66824953 |
| 98 | MP0003984_embryonic_growth_retardation | 0.66455523 |
| 99 | MP0002234_abnormal_pharynx_morphology | 0.65208127 |
| 100 | MP0002796_impaired_skin_barrier | 0.64032366 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.71653087 |
| 2 | Acute encephalopathy (HP:0006846) | 4.64235901 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.44015695 |
| 4 | Increased CSF lactate (HP:0002490) | 4.02152568 |
| 5 | Mitochondrial inheritance (HP:0001427) | 3.88445172 |
| 6 | Cerebral edema (HP:0002181) | 3.81497118 |
| 7 | Hyperglycinemia (HP:0002154) | 3.77061291 |
| 8 | Progressive macrocephaly (HP:0004481) | 3.71847177 |
| 9 | Hepatocellular necrosis (HP:0001404) | 3.51283487 |
| 10 | Increased hepatocellular lipid droplets (HP:0006565) | 3.48512357 |
| 11 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.43260564 |
| 12 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.43260564 |
| 13 | Increased serum pyruvate (HP:0003542) | 3.43057884 |
| 14 | Reticulocytopenia (HP:0001896) | 3.41116286 |
| 15 | Hepatic necrosis (HP:0002605) | 3.30635281 |
| 16 | Increased serum lactate (HP:0002151) | 3.21065344 |
| 17 | Lipid accumulation in hepatocytes (HP:0006561) | 3.20659636 |
| 18 | Microvesicular hepatic steatosis (HP:0001414) | 3.16664346 |
| 19 | Abnormality of serum amino acid levels (HP:0003112) | 3.15898859 |
| 20 | Abnormality of glycolysis (HP:0004366) | 3.15888303 |
| 21 | Lactic acidosis (HP:0003128) | 3.05280642 |
| 22 | Macrocytic anemia (HP:0001972) | 3.02853007 |
| 23 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.97332500 |
| 24 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.95963912 |
| 25 | Colon cancer (HP:0003003) | 2.95545769 |
| 26 | Increased intramyocellular lipid droplets (HP:0012240) | 2.93993170 |
| 27 | Generalized aminoaciduria (HP:0002909) | 2.93450738 |
| 28 | Renal Fanconi syndrome (HP:0001994) | 2.85275195 |
| 29 | Reduced antithrombin III activity (HP:0001976) | 2.67671852 |
| 30 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.67188166 |
| 31 | Abnormality of glycine metabolism (HP:0010895) | 2.67188166 |
| 32 | Lethargy (HP:0001254) | 2.65171368 |
| 33 | Abnormality of alanine metabolism (HP:0010916) | 2.56521299 |
| 34 | Hyperalaninemia (HP:0003348) | 2.56521299 |
| 35 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.56521299 |
| 36 | Hyperglycinuria (HP:0003108) | 2.53809682 |
| 37 | Abnormal number of erythroid precursors (HP:0012131) | 2.53682591 |
| 38 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.52003095 |
| 39 | Abnormality of methionine metabolism (HP:0010901) | 2.48528858 |
| 40 | Exercise intolerance (HP:0003546) | 2.46044019 |
| 41 | Pallor (HP:0000980) | 2.41960823 |
| 42 | Increased muscle lipid content (HP:0009058) | 2.41680769 |
| 43 | Leukodystrophy (HP:0002415) | 2.39282346 |
| 44 | Respiratory failure (HP:0002878) | 2.34960271 |
| 45 | Degeneration of anterior horn cells (HP:0002398) | 2.32231980 |
| 46 | Abnormality of the anterior horn cell (HP:0006802) | 2.32231980 |
| 47 | Hypobetalipoproteinemia (HP:0003563) | 2.26003934 |
| 48 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 2.21188862 |
| 49 | Type I transferrin isoform profile (HP:0003642) | 2.20179399 |
| 50 | Methylmalonic acidemia (HP:0002912) | 2.20170355 |
| 51 | Pancytopenia (HP:0001876) | 2.19391846 |
| 52 | Hypoplasia of the pons (HP:0012110) | 2.17585607 |
| 53 | Abnormal biliary tract physiology (HP:0012439) | 2.16991134 |
| 54 | Bile duct proliferation (HP:0001408) | 2.16991134 |
| 55 | Multiple enchondromatosis (HP:0005701) | 2.13836387 |
| 56 | Methylmalonic aciduria (HP:0012120) | 2.13605528 |
| 57 | Respiratory difficulties (HP:0002880) | 2.13135029 |
| 58 | Supernumerary spleens (HP:0009799) | 2.12683877 |
| 59 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.12645348 |
| 60 | Optic disc pallor (HP:0000543) | 2.05377975 |
| 61 | CNS demyelination (HP:0007305) | 2.03839582 |
| 62 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.03344300 |
| 63 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.03344300 |
| 64 | Abnormal protein glycosylation (HP:0012346) | 2.03344300 |
| 65 | Abnormal glycosylation (HP:0012345) | 2.03344300 |
| 66 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.01743208 |
| 67 | Hypoplastic pelvis (HP:0008839) | 2.00430560 |
| 68 | Abnormal umbilical cord blood vessels (HP:0011403) | 1.98421968 |
| 69 | Single umbilical artery (HP:0001195) | 1.98421968 |
| 70 | Abnormality of the fetal cardiovascular system (HP:0010948) | 1.98421968 |
| 71 | Abnormality of urine glucose concentration (HP:0011016) | 1.97662452 |
| 72 | Glycosuria (HP:0003076) | 1.97662452 |
| 73 | Abnormality of the pons (HP:0007361) | 1.95930979 |
| 74 | Testicular atrophy (HP:0000029) | 1.95336003 |
| 75 | Cerebral hypomyelination (HP:0006808) | 1.95083584 |
| 76 | Ragged-red muscle fibers (HP:0003200) | 1.94611101 |
| 77 | Progressive muscle weakness (HP:0003323) | 1.93634599 |
| 78 | Prolonged partial thromboplastin time (HP:0003645) | 1.91597368 |
| 79 | 3-Methylglutaconic aciduria (HP:0003535) | 1.91589036 |
| 80 | Aplastic anemia (HP:0001915) | 1.89408901 |
| 81 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.88398789 |
| 82 | Abnormal lung lobation (HP:0002101) | 1.86486344 |
| 83 | Delayed CNS myelination (HP:0002188) | 1.83558425 |
| 84 | Premature ovarian failure (HP:0008209) | 1.82396448 |
| 85 | Stenosis of the external auditory canal (HP:0000402) | 1.82182256 |
| 86 | Hyperphosphaturia (HP:0003109) | 1.81350132 |
| 87 | Sparse eyelashes (HP:0000653) | 1.80882624 |
| 88 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 1.80499976 |
| 89 | Nausea (HP:0002018) | 1.79512284 |
| 90 | Dysphonia (HP:0001618) | 1.79506575 |
| 91 | Dicarboxylic aciduria (HP:0003215) | 1.77745077 |
| 92 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.77745077 |
| 93 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 1.76683847 |
| 94 | Metabolic acidosis (HP:0001942) | 1.73973508 |
| 95 | Megaloblastic anemia (HP:0001889) | 1.73309657 |
| 96 | Meckel diverticulum (HP:0002245) | 1.71082601 |
| 97 | Adrenal hypoplasia (HP:0000835) | 1.70756252 |
| 98 | Horseshoe kidney (HP:0000085) | 1.70132522 |
| 99 | X-linked dominant inheritance (HP:0001423) | 1.69671797 |
| 100 | Microretrognathia (HP:0000308) | 1.69355183 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BUB1 | 4.49723764 |
| 2 | NME2 | 3.37394230 |
| 3 | CDC7 | 3.13686251 |
| 4 | VRK2 | 3.09076577 |
| 5 | NEK1 | 2.93917988 |
| 6 | SRPK1 | 2.76099032 |
| 7 | ZAK | 2.73688113 |
| 8 | TTK | 2.51422252 |
| 9 | EIF2AK1 | 2.44698235 |
| 10 | PBK | 2.44432657 |
| 11 | PLK4 | 2.36828861 |
| 12 | TRIM28 | 2.18705782 |
| 13 | MST4 | 2.15631486 |
| 14 | STK16 | 2.05873903 |
| 15 | EIF2AK3 | 1.96931745 |
| 16 | TESK2 | 1.90548487 |
| 17 | PLK3 | 1.80489818 |
| 18 | VRK1 | 1.75616674 |
| 19 | PLK1 | 1.70427532 |
| 20 | TSSK6 | 1.70202129 |
| 21 | WEE1 | 1.68150971 |
| 22 | PDK2 | 1.66406827 |
| 23 | BRSK2 | 1.61700458 |
| 24 | BCKDK | 1.60610980 |
| 25 | NME1 | 1.55483352 |
| 26 | BRAF | 1.49337851 |
| 27 | TESK1 | 1.46635561 |
| 28 | CDK19 | 1.40908976 |
| 29 | MKNK1 | 1.33701195 |
| 30 | DYRK3 | 1.32921279 |
| 31 | ACVR1B | 1.30342040 |
| 32 | PIM2 | 1.25953387 |
| 33 | LIMK1 | 1.23756166 |
| 34 | BMPR1B | 1.19810647 |
| 35 | AURKB | 1.19455381 |
| 36 | MKNK2 | 1.17560397 |
| 37 | CHEK2 | 1.14831304 |
| 38 | SCYL2 | 1.14431828 |
| 39 | STK10 | 1.11220782 |
| 40 | AURKA | 1.10574924 |
| 41 | ARAF | 1.09177848 |
| 42 | DYRK2 | 1.08175715 |
| 43 | MAP4K2 | 1.07286395 |
| 44 | NEK2 | 1.06013790 |
| 45 | BRSK1 | 1.05377514 |
| 46 | ATR | 1.04559926 |
| 47 | MAP2K7 | 0.99598255 |
| 48 | KDR | 0.97315751 |
| 49 | WNK3 | 0.96898616 |
| 50 | PRKCI | 0.96752058 |
| 51 | RPS6KA4 | 0.95414136 |
| 52 | NUAK1 | 0.93861500 |
| 53 | PLK2 | 0.91025173 |
| 54 | WNK4 | 0.85229958 |
| 55 | ERBB4 | 0.83338445 |
| 56 | CSNK1G3 | 0.82034218 |
| 57 | TAF1 | 0.80832915 |
| 58 | ABL2 | 0.79784755 |
| 59 | MAP3K12 | 0.79218386 |
| 60 | TLK1 | 0.78881941 |
| 61 | CSNK2A2 | 0.73235454 |
| 62 | CDK7 | 0.72104418 |
| 63 | CSNK2A1 | 0.69309162 |
| 64 | PASK | 0.67579544 |
| 65 | BCR | 0.66277752 |
| 66 | CHEK1 | 0.65999164 |
| 67 | STK4 | 0.65543631 |
| 68 | GRK7 | 0.63855244 |
| 69 | CSNK1G1 | 0.63661241 |
| 70 | IRAK3 | 0.63537506 |
| 71 | DAPK1 | 0.62144751 |
| 72 | EIF2AK2 | 0.61592194 |
| 73 | MAP3K8 | 0.61294549 |
| 74 | ATM | 0.60836671 |
| 75 | CSNK1G2 | 0.60118820 |
| 76 | PAK4 | 0.58223155 |
| 77 | ERBB3 | 0.57826887 |
| 78 | RPS6KA5 | 0.57340509 |
| 79 | STK3 | 0.55773544 |
| 80 | TGFBR1 | 0.55765563 |
| 81 | FLT3 | 0.55424225 |
| 82 | CSNK1A1L | 0.52604803 |
| 83 | MARK3 | 0.52547748 |
| 84 | MST1R | 0.51343320 |
| 85 | PIM1 | 0.50742267 |
| 86 | EPHA2 | 0.50505128 |
| 87 | STK38L | 0.49296368 |
| 88 | AKT2 | 0.48723518 |
| 89 | STK24 | 0.48078029 |
| 90 | CLK1 | 0.46138546 |
| 91 | MAP3K4 | 0.46034719 |
| 92 | CSNK1E | 0.43582412 |
| 93 | PAK1 | 0.38190184 |
| 94 | OBSCN | 0.36760084 |
| 95 | RPS6KB2 | 0.36440428 |
| 96 | ALK | 0.36040516 |
| 97 | CDK2 | 0.35145419 |
| 98 | STK39 | 0.35028580 |
| 99 | CDK14 | 0.34742146 |
| 100 | CDK3 | 0.34674035 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.29240114 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 3.59475619 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.08703001 |
| 4 | DNA replication_Homo sapiens_hsa03030 | 2.71898376 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 2.70479398 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.57499145 |
| 7 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.54595508 |
| 8 | Mismatch repair_Homo sapiens_hsa03430 | 2.35531333 |
| 9 | Protein export_Homo sapiens_hsa03060 | 2.19133553 |
| 10 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 2.15934233 |
| 11 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 2.08106438 |
| 12 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.03781898 |
| 13 | Huntingtons disease_Homo sapiens_hsa05016 | 1.96959956 |
| 14 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.92881254 |
| 15 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.92542909 |
| 16 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.91865477 |
| 17 | Base excision repair_Homo sapiens_hsa03410 | 1.90575930 |
| 18 | Spliceosome_Homo sapiens_hsa03040 | 1.88541014 |
| 19 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.87002573 |
| 20 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.81679299 |
| 21 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.78679955 |
| 22 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.77983601 |
| 23 | RNA transport_Homo sapiens_hsa03013 | 1.75633370 |
| 24 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.67960141 |
| 25 | Alzheimers disease_Homo sapiens_hsa05010 | 1.62371457 |
| 26 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.57686126 |
| 27 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.53026926 |
| 28 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.49495139 |
| 29 | RNA degradation_Homo sapiens_hsa03018 | 1.49214072 |
| 30 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.42456581 |
| 31 | Homologous recombination_Homo sapiens_hsa03440 | 1.39094698 |
| 32 | Carbon metabolism_Homo sapiens_hsa01200 | 1.37797046 |
| 33 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.34368336 |
| 34 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.33090018 |
| 35 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.32040977 |
| 36 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.31563305 |
| 37 | Sulfur relay system_Homo sapiens_hsa04122 | 1.31080435 |
| 38 | Cell cycle_Homo sapiens_hsa04110 | 1.30955179 |
| 39 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.29347120 |
| 40 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.25439983 |
| 41 | Basal transcription factors_Homo sapiens_hsa03022 | 1.23373253 |
| 42 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.21300315 |
| 43 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.20258139 |
| 44 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.16088507 |
| 45 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.13604370 |
| 46 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.13333673 |
| 47 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.13315340 |
| 48 | Peroxisome_Homo sapiens_hsa04146 | 1.09894707 |
| 49 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.06484630 |
| 50 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.04975504 |
| 51 | Purine metabolism_Homo sapiens_hsa00230 | 1.02657870 |
| 52 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.00096982 |
| 53 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.99594849 |
| 54 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.95353198 |
| 55 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.92515506 |
| 56 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.91286970 |
| 57 | Retinol metabolism_Homo sapiens_hsa00830 | 0.91153691 |
| 58 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.90137535 |
| 59 | Metabolic pathways_Homo sapiens_hsa01100 | 0.86584862 |
| 60 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.85327685 |
| 61 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.84825542 |
| 62 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.84481849 |
| 63 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.83308204 |
| 64 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.79281438 |
| 65 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.77394261 |
| 66 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.76356902 |
| 67 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.75242258 |
| 68 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.73921033 |
| 69 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.72928723 |
| 70 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.69543719 |
| 71 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.66800719 |
| 72 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.65868793 |
| 73 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.63561046 |
| 74 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.63120632 |
| 75 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.61022365 |
| 76 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.60095158 |
| 77 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.58782355 |
| 78 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.57082245 |
| 79 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.53052418 |
| 80 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.52814020 |
| 81 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.50635400 |
| 82 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.48703244 |
| 83 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.48244598 |
| 84 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.44108126 |
| 85 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.42377739 |
| 86 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.40822416 |
| 87 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.39686093 |
| 88 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.39445305 |
| 89 | Galactose metabolism_Homo sapiens_hsa00052 | 0.39378428 |
| 90 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.37112699 |
| 91 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.33383752 |
| 92 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.26434049 |
| 93 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.26337082 |
| 94 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.26328857 |
| 95 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.25894144 |
| 96 | Phototransduction_Homo sapiens_hsa04744 | 0.25114860 |
| 97 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.21191013 |
| 98 | Alcoholism_Homo sapiens_hsa05034 | 0.17415070 |
| 99 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.17300566 |
| 100 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.15384283 |

