Rank | Gene Set | Z-score |
---|---|---|
1 | monoubiquitinated protein deubiquitination (GO:0035520) | 4.01088862 |
2 | ribonucleoprotein complex disassembly (GO:0032988) | 3.75817953 |
3 | centriole replication (GO:0007099) | 3.57511901 |
4 | V(D)J recombination (GO:0033151) | 3.44313242 |
5 | organelle disassembly (GO:1903008) | 3.40584078 |
6 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.38323252 |
7 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.34572205 |
8 | resolution of meiotic recombination intermediates (GO:0000712) | 3.22913492 |
9 | response to pheromone (GO:0019236) | 3.21658908 |
10 | protein-cofactor linkage (GO:0018065) | 3.20666100 |
11 | nonmotile primary cilium assembly (GO:0035058) | 3.20664403 |
12 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 3.19491743 |
13 | rRNA methylation (GO:0031167) | 3.14450211 |
14 | protein K11-linked deubiquitination (GO:0035871) | 3.13084881 |
15 | prenylation (GO:0097354) | 3.12772068 |
16 | protein prenylation (GO:0018342) | 3.12772068 |
17 | mitotic sister chromatid cohesion (GO:0007064) | 3.09745331 |
18 | negative regulation of DNA recombination (GO:0045910) | 3.01903049 |
19 | behavioral response to nicotine (GO:0035095) | 2.99927903 |
20 | spermatid nucleus differentiation (GO:0007289) | 2.99813853 |
21 | positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902110 | 2.92689217 |
22 | mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686) | 2.92689217 |
23 | pseudouridine synthesis (GO:0001522) | 2.91048977 |
24 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.89377756 |
25 | negative regulation of oligodendrocyte differentiation (GO:0048715) | 2.87858232 |
26 | respiratory chain complex IV assembly (GO:0008535) | 2.86354549 |
27 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.86216469 |
28 | termination of RNA polymerase III transcription (GO:0006386) | 2.86216469 |
29 | termination of RNA polymerase I transcription (GO:0006363) | 2.85693472 |
30 | 7-methylguanosine mRNA capping (GO:0006370) | 2.83853800 |
31 | regulation of centriole replication (GO:0046599) | 2.80316311 |
32 | histone H2A ubiquitination (GO:0033522) | 2.80008660 |
33 | epithelial cilium movement (GO:0003351) | 2.80008268 |
34 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.79864287 |
35 | rRNA modification (GO:0000154) | 2.76382207 |
36 | spliceosomal complex assembly (GO:0000245) | 2.75692973 |
37 | microtubule anchoring (GO:0034453) | 2.74789146 |
38 | 7-methylguanosine RNA capping (GO:0009452) | 2.73747856 |
39 | RNA capping (GO:0036260) | 2.73747856 |
40 | establishment of protein localization to Golgi (GO:0072600) | 2.72941246 |
41 | cellular response to ethanol (GO:0071361) | 2.70760642 |
42 | regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510) | 2.68930279 |
43 | CENP-A containing nucleosome assembly (GO:0034080) | 2.68213911 |
44 | protein targeting to Golgi (GO:0000042) | 2.68202135 |
45 | double-strand break repair via homologous recombination (GO:0000724) | 2.67514869 |
46 | replication fork processing (GO:0031297) | 2.66688519 |
47 | alternative mRNA splicing, via spliceosome (GO:0000380) | 2.65826390 |
48 | transcription from RNA polymerase III promoter (GO:0006383) | 2.65799732 |
49 | chromatin remodeling at centromere (GO:0031055) | 2.64838356 |
50 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.64738874 |
51 | microtubule nucleation (GO:0007020) | 2.64695990 |
52 | respiratory electron transport chain (GO:0022904) | 2.63988527 |
53 | recombinational repair (GO:0000725) | 2.63929148 |
54 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.63919135 |
55 | somatic diversification of immune receptors (GO:0002200) | 2.63827099 |
56 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.63260235 |
57 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.63260235 |
58 | cilium movement (GO:0003341) | 2.63201143 |
59 | protein complex biogenesis (GO:0070271) | 2.62630822 |
60 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.61457942 |
61 | NADH dehydrogenase complex assembly (GO:0010257) | 2.61457942 |
62 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.61457942 |
63 | histone mRNA metabolic process (GO:0008334) | 2.59726243 |
64 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.59722313 |
65 | cilium or flagellum-dependent cell motility (GO:0001539) | 2.59258642 |
66 | electron transport chain (GO:0022900) | 2.58496982 |
67 | rRNA catabolic process (GO:0016075) | 2.56957884 |
68 | neural tube formation (GO:0001841) | 2.56655171 |
69 | ribosomal large subunit biogenesis (GO:0042273) | 2.56239069 |
70 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.55920223 |
71 | transcription initiation from RNA polymerase I promoter (GO:0006361) | 2.53599409 |
72 | DNA double-strand break processing (GO:0000729) | 2.53487888 |
73 | intraciliary transport (GO:0042073) | 2.53351079 |
74 | anterograde synaptic vesicle transport (GO:0048490) | 2.53314776 |
75 | DNA topological change (GO:0006265) | 2.52897074 |
76 | replicative senescence (GO:0090399) | 2.52548818 |
77 | somatic diversification of immune receptors via germline recombination within a single locus (GO:000 | 2.51893974 |
78 | somatic cell DNA recombination (GO:0016444) | 2.51893974 |
79 | ATP synthesis coupled proton transport (GO:0015986) | 2.51149647 |
80 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.51149647 |
81 | maturation of 5.8S rRNA (GO:0000460) | 2.49728901 |
82 | histone H2A monoubiquitination (GO:0035518) | 2.48700443 |
83 | ribosome assembly (GO:0042255) | 2.48316104 |
84 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.47203050 |
85 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.47203050 |
86 | mitochondrial RNA metabolic process (GO:0000959) | 2.46639163 |
87 | positive regulation of mRNA processing (GO:0050685) | 2.46112020 |
88 | positive regulation of histone H3-K4 methylation (GO:0051571) | 2.44795293 |
89 | ncRNA catabolic process (GO:0034661) | 2.44654158 |
90 | peptidyl-histidine modification (GO:0018202) | 2.44350959 |
91 | attachment of spindle microtubules to kinetochore (GO:0008608) | 2.43738772 |
92 | regulation of acyl-CoA biosynthetic process (GO:0050812) | 2.40625322 |
93 | centriole assembly (GO:0098534) | 2.40198457 |
94 | transcription elongation from RNA polymerase II promoter (GO:0006368) | 2.39998178 |
95 | histone monoubiquitination (GO:0010390) | 2.38658752 |
96 | pyrimidine dimer repair (GO:0006290) | 2.37393531 |
97 | retrograde transport, vesicle recycling within Golgi (GO:0000301) | 2.34400387 |
98 | histone exchange (GO:0043486) | 2.33967497 |
99 | histone ubiquitination (GO:0016574) | 2.33733817 |
100 | tRNA processing (GO:0008033) | 2.32491833 |
Rank | Gene Set | Z-score |
---|---|---|
1 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 3.80258119 |
2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.03058142 |
3 | * KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.98088848 |
4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.93437683 |
5 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.86846126 |
6 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.70942710 |
7 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.70725540 |
8 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.65865480 |
9 | FUS_26573619_Chip-Seq_HEK293_Human | 2.60922229 |
10 | EWS_26573619_Chip-Seq_HEK293_Human | 2.55428901 |
11 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.44664827 |
12 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.37686566 |
13 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.33769162 |
14 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.29663465 |
15 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.22812914 |
16 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.19578749 |
17 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 2.12199969 |
18 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.08999555 |
19 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.05880123 |
20 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.02914709 |
21 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.02807380 |
22 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.98944902 |
23 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.94106313 |
24 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.93967841 |
25 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.91787312 |
26 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.89089580 |
27 | VDR_22108803_ChIP-Seq_LS180_Human | 1.88498475 |
28 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.87651789 |
29 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.74395147 |
30 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.73458485 |
31 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.72277740 |
32 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.70779533 |
33 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.70720375 |
34 | P300_19829295_ChIP-Seq_ESCs_Human | 1.68804709 |
35 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.67846244 |
36 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.63648822 |
37 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.58661820 |
38 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.53518938 |
39 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.49694397 |
40 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.49276247 |
41 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.44207392 |
42 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.43704397 |
43 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.41018922 |
44 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.40766500 |
45 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.30159752 |
46 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.29694880 |
47 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.28561295 |
48 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.28431729 |
49 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.26318949 |
50 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.25621676 |
51 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.24968718 |
52 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.22415806 |
53 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.22090454 |
54 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.21940409 |
55 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.21658064 |
56 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.21387454 |
57 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.20851320 |
58 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.20518310 |
59 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.19401275 |
60 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.18133695 |
61 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.17579358 |
62 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.16717758 |
63 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.16211769 |
64 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.14660073 |
65 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.14402074 |
66 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.14231919 |
67 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.14231919 |
68 | STAT3_23295773_ChIP-Seq_U87_Human | 1.12666450 |
69 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.11629505 |
70 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.09942448 |
71 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.09781012 |
72 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.09489121 |
73 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.08638888 |
74 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.08132761 |
75 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.07438178 |
76 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.04273500 |
77 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.03473146 |
78 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.03473146 |
79 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.02784774 |
80 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.02390564 |
81 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.02138339 |
82 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.01723949 |
83 | TCF4_23295773_ChIP-Seq_U87_Human | 1.01212903 |
84 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.00152116 |
85 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.99728991 |
86 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.99547155 |
87 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 0.98931909 |
88 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.98784162 |
89 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 0.98144380 |
90 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.96843888 |
91 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.96420879 |
92 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 0.94778968 |
93 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.94265938 |
94 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.94056013 |
95 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.93928168 |
96 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.93484935 |
97 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 0.93000028 |
98 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.92599847 |
99 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.92251303 |
100 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.92175199 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008057_abnormal_DNA_replication | 3.19375907 |
2 | MP0010094_abnormal_chromosome_stability | 2.68650136 |
3 | MP0004147_increased_porphyrin_level | 2.64145289 |
4 | MP0003122_maternal_imprinting | 2.61040996 |
5 | MP0000569_abnormal_digit_pigmentation | 2.57298382 |
6 | MP0008877_abnormal_DNA_methylation | 2.45491858 |
7 | MP0003890_abnormal_embryonic-extraembry | 2.23496941 |
8 | MP0002938_white_spotting | 2.13245706 |
9 | MP0002102_abnormal_ear_morphology | 2.12308578 |
10 | MP0008995_early_reproductive_senescence | 2.05165923 |
11 | MP0002638_abnormal_pupillary_reflex | 1.99770950 |
12 | MP0008058_abnormal_DNA_repair | 1.93084417 |
13 | MP0003121_genomic_imprinting | 1.91848766 |
14 | MP0009697_abnormal_copulation | 1.90987124 |
15 | MP0004142_abnormal_muscle_tone | 1.90775484 |
16 | MP0006292_abnormal_olfactory_placode | 1.86520112 |
17 | MP0002132_abnormal_respiratory_system | 1.85961021 |
18 | MP0001984_abnormal_olfaction | 1.85207942 |
19 | MP0002009_preneoplasia | 1.75849276 |
20 | MP0001293_anophthalmia | 1.73762809 |
21 | MP0000372_irregular_coat_pigmentation | 1.72884732 |
22 | MP0001529_abnormal_vocalization | 1.71700978 |
23 | MP0006072_abnormal_retinal_apoptosis | 1.67858127 |
24 | MP0005253_abnormal_eye_physiology | 1.66856509 |
25 | MP0002095_abnormal_skin_pigmentation | 1.57610131 |
26 | MP0005551_abnormal_eye_electrophysiolog | 1.56581067 |
27 | MP0002876_abnormal_thyroid_physiology | 1.54716923 |
28 | MP0004957_abnormal_blastocyst_morpholog | 1.50980249 |
29 | MP0005379_endocrine/exocrine_gland_phen | 1.50956803 |
30 | MP0009046_muscle_twitch | 1.44364913 |
31 | MP0000631_abnormal_neuroendocrine_gland | 1.43362885 |
32 | MP0004215_abnormal_myocardial_fiber | 1.38340096 |
33 | MP0004084_abnormal_cardiac_muscle | 1.34240333 |
34 | MP0005075_abnormal_melanosome_morpholog | 1.33263282 |
35 | MP0003646_muscle_fatigue | 1.31269435 |
36 | MP0003567_abnormal_fetal_cardiomyocyte | 1.29306592 |
37 | MP0003221_abnormal_cardiomyocyte_apopto | 1.28289042 |
38 | MP0002160_abnormal_reproductive_system | 1.28223505 |
39 | MP0003787_abnormal_imprinting | 1.27783031 |
40 | MP0006036_abnormal_mitochondrial_physio | 1.25324202 |
41 | MP0000427_abnormal_hair_cycle | 1.25228337 |
42 | MP0003077_abnormal_cell_cycle | 1.25191068 |
43 | MP0006035_abnormal_mitochondrial_morpho | 1.22938800 |
44 | MP0005410_abnormal_fertilization | 1.21397060 |
45 | MP0001286_abnormal_eye_development | 1.18944601 |
46 | MP0005645_abnormal_hypothalamus_physiol | 1.17653597 |
47 | MP0008872_abnormal_physiological_respon | 1.17205388 |
48 | MP0005391_vision/eye_phenotype | 1.14041684 |
49 | MP0001486_abnormal_startle_reflex | 1.12679860 |
50 | MP0001929_abnormal_gametogenesis | 1.12410501 |
51 | MP0002233_abnormal_nose_morphology | 1.08786134 |
52 | MP0003937_abnormal_limbs/digits/tail_de | 1.07439813 |
53 | MP0002837_dystrophic_cardiac_calcinosis | 1.06717069 |
54 | MP0002166_altered_tumor_susceptibility | 1.06082999 |
55 | MP0002006_tumorigenesis | 1.04315175 |
56 | MP0003718_maternal_effect | 1.03891749 |
57 | MP0003786_premature_aging | 1.03624498 |
58 | MP0001697_abnormal_embryo_size | 1.02156269 |
59 | MP0003111_abnormal_nucleus_morphology | 0.99768844 |
60 | MP0000778_abnormal_nervous_system | 0.99357780 |
61 | MP0002210_abnormal_sex_determination | 0.96749560 |
62 | MP0003880_abnormal_central_pattern | 0.96059660 |
63 | MP0003698_abnormal_male_reproductive | 0.94390939 |
64 | MP0004742_abnormal_vestibular_system | 0.93733512 |
65 | MP0004133_heterotaxia | 0.93115742 |
66 | MP0000647_abnormal_sebaceous_gland | 0.91363312 |
67 | MP0005195_abnormal_posterior_eye | 0.90956522 |
68 | MP0009745_abnormal_behavioral_response | 0.90851918 |
69 | MP0008789_abnormal_olfactory_epithelium | 0.89811332 |
70 | MP0002163_abnormal_gland_morphology | 0.88814341 |
71 | MP0002088_abnormal_embryonic_growth/wei | 0.87624399 |
72 | MP0003136_yellow_coat_color | 0.87179495 |
73 | MP0005389_reproductive_system_phenotype | 0.86599432 |
74 | MP0003984_embryonic_growth_retardation | 0.86394621 |
75 | MP0004197_abnormal_fetal_growth/weight/ | 0.85497892 |
76 | MP0002928_abnormal_bile_duct | 0.84914560 |
77 | MP0001879_abnormal_lymphatic_vessel | 0.83374399 |
78 | MP0000653_abnormal_sex_gland | 0.81652696 |
79 | MP0002084_abnormal_developmental_patter | 0.81534131 |
80 | MP0005084_abnormal_gallbladder_morpholo | 0.81278229 |
81 | MP0004885_abnormal_endolymph | 0.81091605 |
82 | MP0002067_abnormal_sensory_capabilities | 0.80640069 |
83 | MP0001919_abnormal_reproductive_system | 0.80448543 |
84 | MP0003950_abnormal_plasma_membrane | 0.78695345 |
85 | MP0001324_abnormal_eye_pigmentation | 0.77725111 |
86 | MP0002127_abnormal_cardiovascular_syste | 0.77235248 |
87 | MP0005380_embryogenesis_phenotype | 0.77231234 |
88 | MP0001672_abnormal_embryogenesis/_devel | 0.77231234 |
89 | MP0003693_abnormal_embryo_hatching | 0.76516630 |
90 | MP0001145_abnormal_male_reproductive | 0.75957524 |
91 | MP0003186_abnormal_redox_activity | 0.74890261 |
92 | MP0005266_abnormal_metabolism | 0.74206172 |
93 | MP0003755_abnormal_palate_morphology | 0.74032709 |
94 | MP0003861_abnormal_nervous_system | 0.73536377 |
95 | MP0003195_calcinosis | 0.72864455 |
96 | MP0002092_abnormal_eye_morphology | 0.72705363 |
97 | MP0003935_abnormal_craniofacial_develop | 0.72591814 |
98 | MP0002184_abnormal_innervation | 0.72353618 |
99 | MP0002277_abnormal_respiratory_mucosa | 0.72162183 |
100 | MP0002090_abnormal_vision | 0.71071078 |
Rank | Gene Set | Z-score |
---|---|---|
1 | B lymphocytopenia (HP:0010976) | 4.70317467 |
2 | Abnormality of B cell number (HP:0010975) | 4.16135666 |
3 | Hypoplasia of the thymus (HP:0000778) | 3.80808663 |
4 | Increased hepatocellular lipid droplets (HP:0006565) | 3.30476945 |
5 | Thyroiditis (HP:0100646) | 3.29564685 |
6 | Severe combined immunodeficiency (HP:0004430) | 3.17354695 |
7 | Medial flaring of the eyebrow (HP:0010747) | 3.12057637 |
8 | Lipid accumulation in hepatocytes (HP:0006561) | 2.95928861 |
9 | Progressive macrocephaly (HP:0004481) | 2.71912337 |
10 | Acute necrotizing encephalopathy (HP:0006965) | 2.69694806 |
11 | Abnormality of midbrain morphology (HP:0002418) | 2.67151048 |
12 | Molar tooth sign on MRI (HP:0002419) | 2.67151048 |
13 | Papillary thyroid carcinoma (HP:0002895) | 2.63996074 |
14 | Pancreatic cysts (HP:0001737) | 2.63898858 |
15 | Panhypogammaglobulinemia (HP:0003139) | 2.59226499 |
16 | Hypoproteinemia (HP:0003075) | 2.56401910 |
17 | Gait imbalance (HP:0002141) | 2.55661951 |
18 | Chronic hepatic failure (HP:0100626) | 2.54192160 |
19 | Congenital primary aphakia (HP:0007707) | 2.51455767 |
20 | Methylmalonic acidemia (HP:0002912) | 2.45791764 |
21 | 3-Methylglutaconic aciduria (HP:0003535) | 2.43874010 |
22 | Nephrogenic diabetes insipidus (HP:0009806) | 2.43723551 |
23 | Pancreatic fibrosis (HP:0100732) | 2.38628980 |
24 | Abnormality of alanine metabolism (HP:0010916) | 2.37899480 |
25 | Hyperalaninemia (HP:0003348) | 2.37899480 |
26 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.37899480 |
27 | Combined immunodeficiency (HP:0005387) | 2.36396876 |
28 | Mitochondrial inheritance (HP:0001427) | 2.34729361 |
29 | Acute encephalopathy (HP:0006846) | 2.30554343 |
30 | Increased CSF lactate (HP:0002490) | 2.30074495 |
31 | Nephronophthisis (HP:0000090) | 2.28486187 |
32 | Neuroendocrine neoplasm (HP:0100634) | 2.25103017 |
33 | Renal Fanconi syndrome (HP:0001994) | 2.17521312 |
34 | Genital tract atresia (HP:0001827) | 2.17093100 |
35 | Poor coordination (HP:0002370) | 2.16455991 |
36 | Renal cortical cysts (HP:0000803) | 2.15529243 |
37 | Thyroid carcinoma (HP:0002890) | 2.14849894 |
38 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.14373299 |
39 | Abnormality of chromosome stability (HP:0003220) | 2.14292464 |
40 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.14247836 |
41 | Abnormality of the pons (HP:0007361) | 2.12612424 |
42 | Vaginal atresia (HP:0000148) | 2.11037746 |
43 | Pheochromocytoma (HP:0002666) | 2.08887089 |
44 | Volvulus (HP:0002580) | 2.07202193 |
45 | Abnormality of the labia minora (HP:0012880) | 2.07190157 |
46 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.07049707 |
47 | Atonic seizures (HP:0010819) | 2.02768282 |
48 | Sensory axonal neuropathy (HP:0003390) | 2.02420040 |
49 | True hermaphroditism (HP:0010459) | 2.01885451 |
50 | Median cleft lip (HP:0000161) | 1.96229319 |
51 | Chromsome breakage (HP:0040012) | 1.95052280 |
52 | Abnormality of the septum pellucidum (HP:0007375) | 1.94996704 |
53 | Homocystinuria (HP:0002156) | 1.94843574 |
54 | Abnormality of homocysteine metabolism (HP:0010919) | 1.94843574 |
55 | Birth length less than 3rd percentile (HP:0003561) | 1.94582760 |
56 | Febrile seizures (HP:0002373) | 1.94514788 |
57 | Abnormality of the renal cortex (HP:0011035) | 1.93008979 |
58 | Erythroderma (HP:0001019) | 1.91887965 |
59 | Rhabdomyosarcoma (HP:0002859) | 1.90043416 |
60 | Constricted visual fields (HP:0001133) | 1.88192990 |
61 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.86318112 |
62 | Abnormality of the ileum (HP:0001549) | 1.86059352 |
63 | Abnormality of the renal medulla (HP:0100957) | 1.85876052 |
64 | Hypoplasia of the pons (HP:0012110) | 1.84391743 |
65 | Medulloblastoma (HP:0002885) | 1.84335429 |
66 | Biliary tract neoplasm (HP:0100574) | 1.83496421 |
67 | Nephroblastoma (Wilms tumor) (HP:0002667) | 1.83199287 |
68 | Abnormality of methionine metabolism (HP:0010901) | 1.82931161 |
69 | Meckel diverticulum (HP:0002245) | 1.81866812 |
70 | Supernumerary spleens (HP:0009799) | 1.80874201 |
71 | Eosinophilia (HP:0001880) | 1.79801262 |
72 | Abnormal ciliary motility (HP:0012262) | 1.78359502 |
73 | Attenuation of retinal blood vessels (HP:0007843) | 1.77771411 |
74 | Abnormal biliary tract morphology (HP:0012440) | 1.76950710 |
75 | Increased serum lactate (HP:0002151) | 1.76637322 |
76 | Abnormal hemoglobin (HP:0011902) | 1.75115845 |
77 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.74482583 |
78 | Hypothermia (HP:0002045) | 1.74379388 |
79 | Exertional dyspnea (HP:0002875) | 1.72228804 |
80 | Stenosis of the external auditory canal (HP:0000402) | 1.70478695 |
81 | Embryonal renal neoplasm (HP:0011794) | 1.68909959 |
82 | Abnormality of eosinophils (HP:0001879) | 1.67048349 |
83 | Abnormality of the pancreatic islet cells (HP:0006476) | 1.65900673 |
84 | Abnormality of endocrine pancreas physiology (HP:0012093) | 1.65900673 |
85 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.65170978 |
86 | Tubulointerstitial nephritis (HP:0001970) | 1.64813825 |
87 | Cerebellar dysplasia (HP:0007033) | 1.64767822 |
88 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.64637638 |
89 | Intestinal atresia (HP:0011100) | 1.64503955 |
90 | Prominent nasal bridge (HP:0000426) | 1.64463267 |
91 | T lymphocytopenia (HP:0005403) | 1.62822698 |
92 | Hepatic necrosis (HP:0002605) | 1.62649631 |
93 | Optic disc pallor (HP:0000543) | 1.62572295 |
94 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.62173781 |
95 | Hypoglycemic coma (HP:0001325) | 1.61622063 |
96 | Cerebral edema (HP:0002181) | 1.60567837 |
97 | Hepatoblastoma (HP:0002884) | 1.59841994 |
98 | Hepatocellular necrosis (HP:0001404) | 1.59656606 |
99 | Absent septum pellucidum (HP:0001331) | 1.58734328 |
100 | Absent thumb (HP:0009777) | 1.58135854 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MST4 | 3.36379493 |
2 | EIF2AK3 | 3.22576528 |
3 | BRD4 | 2.76101487 |
4 | EIF2AK1 | 2.75261365 |
5 | MAP4K2 | 2.48501624 |
6 | BRSK2 | 2.42951059 |
7 | FRK | 2.39399610 |
8 | BMPR1B | 2.38800424 |
9 | PNCK | 2.18014082 |
10 | SRPK1 | 2.17877886 |
11 | TNIK | 2.09557953 |
12 | PINK1 | 2.09438947 |
13 | ERBB3 | 2.07206729 |
14 | STK16 | 2.06614781 |
15 | INSRR | 2.06420929 |
16 | MAP3K12 | 1.91567345 |
17 | PBK | 1.86583231 |
18 | ZAK | 1.83959072 |
19 | MKNK2 | 1.83485267 |
20 | WNK3 | 1.76704275 |
21 | MAP3K4 | 1.66205817 |
22 | DYRK3 | 1.60948446 |
23 | MKNK1 | 1.50344251 |
24 | WEE1 | 1.31102733 |
25 | TAOK3 | 1.30026964 |
26 | WNK4 | 1.25855500 |
27 | AKT3 | 1.23195949 |
28 | TRIM28 | 1.21759973 |
29 | NUAK1 | 1.21117659 |
30 | BCR | 1.19096065 |
31 | CDC7 | 1.14793863 |
32 | MAPK13 | 1.13106948 |
33 | MAP3K2 | 1.05860494 |
34 | PLK3 | 1.04871627 |
35 | SGK2 | 1.01530858 |
36 | PLK4 | 1.01432048 |
37 | ACVR1B | 1.00004781 |
38 | YES1 | 0.98349339 |
39 | LATS1 | 0.97927896 |
40 | OBSCN | 0.96890180 |
41 | NLK | 0.96064915 |
42 | NEK1 | 0.93642618 |
43 | STK38L | 0.93533840 |
44 | CAMKK2 | 0.91867674 |
45 | CASK | 0.87754472 |
46 | KSR1 | 0.87134867 |
47 | PLK2 | 0.85795218 |
48 | RPS6KA4 | 0.85659956 |
49 | WNK1 | 0.83830702 |
50 | RPS6KB1 | 0.82174128 |
51 | TSSK6 | 0.76799043 |
52 | MAP2K4 | 0.76116340 |
53 | PLK1 | 0.74032994 |
54 | VRK1 | 0.71878880 |
55 | STK3 | 0.69922560 |
56 | SGK223 | 0.64830642 |
57 | SGK494 | 0.64830642 |
58 | CSNK1G1 | 0.64706956 |
59 | FGFR1 | 0.64346306 |
60 | FGFR2 | 0.63603899 |
61 | CSNK1E | 0.62020071 |
62 | PAK3 | 0.60541324 |
63 | ATR | 0.60129133 |
64 | CDK9 | 0.60060329 |
65 | NTRK3 | 0.59962746 |
66 | STK39 | 0.58407283 |
67 | CHEK2 | 0.58384367 |
68 | CDK3 | 0.57602363 |
69 | ATM | 0.57304714 |
70 | CHEK1 | 0.57244678 |
71 | NEK9 | 0.56188394 |
72 | NTRK2 | 0.55312147 |
73 | PRKCE | 0.53721420 |
74 | DYRK2 | 0.51526290 |
75 | TTK | 0.51391023 |
76 | PRKAA2 | 0.50636303 |
77 | SGK1 | 0.50312336 |
78 | MARK1 | 0.48596904 |
79 | PRKACB | 0.48275321 |
80 | PHKG2 | 0.48255481 |
81 | PHKG1 | 0.48255481 |
82 | DYRK1B | 0.47072016 |
83 | TLK1 | 0.45609958 |
84 | PRKAA1 | 0.45083724 |
85 | CSNK1A1L | 0.44454788 |
86 | PRKG1 | 0.44171108 |
87 | OXSR1 | 0.43003708 |
88 | RPS6KA5 | 0.41989543 |
89 | PRKCG | 0.41481860 |
90 | SGK3 | 0.40792343 |
91 | CSNK1D | 0.40454741 |
92 | RAF1 | 0.39650099 |
93 | UHMK1 | 0.39590296 |
94 | TAF1 | 0.39054552 |
95 | CSNK1G2 | 0.38846430 |
96 | ADRBK2 | 0.38312181 |
97 | TEC | 0.38092657 |
98 | TRPM7 | 0.37014302 |
99 | RPS6KB2 | 0.36902627 |
100 | EPHA4 | 0.35802861 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Protein export_Homo sapiens_hsa03060 | 3.96395028 |
2 | Basal transcription factors_Homo sapiens_hsa03022 | 3.34796764 |
3 | Non-homologous end-joining_Homo sapiens_hsa03450 | 3.16080779 |
4 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.03238153 |
5 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.97613152 |
6 | RNA polymerase_Homo sapiens_hsa03020 | 2.96605181 |
7 | Parkinsons disease_Homo sapiens_hsa05012 | 2.65485568 |
8 | Ribosome_Homo sapiens_hsa03010 | 2.56384458 |
9 | Homologous recombination_Homo sapiens_hsa03440 | 2.54826307 |
10 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.45384725 |
11 | RNA degradation_Homo sapiens_hsa03018 | 2.30305914 |
12 | RNA transport_Homo sapiens_hsa03013 | 2.25106956 |
13 | Huntingtons disease_Homo sapiens_hsa05016 | 2.09716830 |
14 | Mismatch repair_Homo sapiens_hsa03430 | 2.03447920 |
15 | Circadian rhythm_Homo sapiens_hsa04710 | 2.01534672 |
16 | Spliceosome_Homo sapiens_hsa03040 | 1.98720808 |
17 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.93910881 |
18 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.92244818 |
19 | Alzheimers disease_Homo sapiens_hsa05010 | 1.76332747 |
20 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.72331031 |
21 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.71106543 |
22 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.62686252 |
23 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.62595788 |
24 | Nicotine addiction_Homo sapiens_hsa05033 | 1.59236865 |
25 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.49509860 |
26 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.47053428 |
27 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.42677158 |
28 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.42556615 |
29 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.42524825 |
30 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.41183626 |
31 | Proteasome_Homo sapiens_hsa03050 | 1.39626697 |
32 | Olfactory transduction_Homo sapiens_hsa04740 | 1.34454730 |
33 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.27179457 |
34 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.15788816 |
35 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.07178586 |
36 | Taste transduction_Homo sapiens_hsa04742 | 1.04662935 |
37 | Phototransduction_Homo sapiens_hsa04744 | 1.03784296 |
38 | Cell cycle_Homo sapiens_hsa04110 | 1.02988261 |
39 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.00216074 |
40 | DNA replication_Homo sapiens_hsa03030 | 0.98630858 |
41 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.95500668 |
42 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.95484040 |
43 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.95058078 |
44 | Alcoholism_Homo sapiens_hsa05034 | 0.91084263 |
45 | Purine metabolism_Homo sapiens_hsa00230 | 0.90120754 |
46 | GABAergic synapse_Homo sapiens_hsa04727 | 0.81687114 |
47 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.81050137 |
48 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.80220996 |
49 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.79597761 |
50 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.74305580 |
51 | Morphine addiction_Homo sapiens_hsa05032 | 0.74301603 |
52 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.73360050 |
53 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.73274336 |
54 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.72802814 |
55 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.69829806 |
56 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.69547894 |
57 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.68816700 |
58 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.65515172 |
59 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.62737887 |
60 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.59693060 |
61 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.59158531 |
62 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.58199407 |
63 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.57510088 |
64 | Peroxisome_Homo sapiens_hsa04146 | 0.57492895 |
65 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.56063429 |
66 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.55942970 |
67 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.55353821 |
68 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.50084664 |
69 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.48872036 |
70 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.48416654 |
71 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.48129686 |
72 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.47880052 |
73 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.47864982 |
74 | Metabolic pathways_Homo sapiens_hsa01100 | 0.45520359 |
75 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.44162324 |
76 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.41723983 |
77 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.41483008 |
78 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.41178676 |
79 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.39468544 |
80 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.38650213 |
81 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.35914378 |
82 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.35861366 |
83 | Mineral absorption_Homo sapiens_hsa04978 | 0.34715636 |
84 | Circadian entrainment_Homo sapiens_hsa04713 | 0.28049998 |
85 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.27527347 |
86 | Thyroid cancer_Homo sapiens_hsa05216 | 0.26503977 |
87 | Colorectal cancer_Homo sapiens_hsa05210 | 0.25959845 |
88 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.25320256 |
89 | Cocaine addiction_Homo sapiens_hsa05030 | 0.24752164 |
90 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.24606062 |
91 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.23778536 |
92 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.23387576 |
93 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.22417446 |
94 | Base excision repair_Homo sapiens_hsa03410 | 0.21427985 |
95 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.20237493 |
96 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.19169241 |
97 | Long-term depression_Homo sapiens_hsa04730 | 0.18542288 |
98 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.17800330 |
99 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.17700809 |
100 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.17597909 |