

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | proteasome assembly (GO:0043248) | 4.54396284 |
| 2 | nuclear pore organization (GO:0006999) | 4.39316929 |
| 3 | nuclear pore complex assembly (GO:0051292) | 4.33124929 |
| 4 | CENP-A containing nucleosome assembly (GO:0034080) | 4.31724733 |
| 5 | chromatin remodeling at centromere (GO:0031055) | 4.23402397 |
| 6 | ribosome assembly (GO:0042255) | 4.17759760 |
| 7 | cullin deneddylation (GO:0010388) | 4.17517833 |
| 8 | DNA replication checkpoint (GO:0000076) | 4.15823345 |
| 9 | DNA double-strand break processing (GO:0000729) | 4.05619231 |
| 10 | protein localization to kinetochore (GO:0034501) | 4.02704697 |
| 11 | mitotic metaphase plate congression (GO:0007080) | 3.87425594 |
| 12 | protein deneddylation (GO:0000338) | 3.83979322 |
| 13 | metaphase plate congression (GO:0051310) | 3.77919529 |
| 14 | mitotic sister chromatid cohesion (GO:0007064) | 3.77127874 |
| 15 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.75701600 |
| 16 | non-recombinational repair (GO:0000726) | 3.75701600 |
| 17 | histone exchange (GO:0043486) | 3.75106144 |
| 18 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.74458111 |
| 19 | purine nucleobase biosynthetic process (GO:0009113) | 3.73705492 |
| 20 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.68405784 |
| 21 | spindle checkpoint (GO:0031577) | 3.66508639 |
| 22 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.63056819 |
| 23 | mitotic sister chromatid segregation (GO:0000070) | 3.62010468 |
| 24 | sister chromatid segregation (GO:0000819) | 3.60412345 |
| 25 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.58596051 |
| 26 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.58577510 |
| 27 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.58577510 |
| 28 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.58492811 |
| 29 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.55470589 |
| 30 | IMP biosynthetic process (GO:0006188) | 3.53244814 |
| 31 | regulation of DNA endoreduplication (GO:0032875) | 3.51007561 |
| 32 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.50377939 |
| 33 | mitotic spindle checkpoint (GO:0071174) | 3.49963140 |
| 34 | replication fork processing (GO:0031297) | 3.49122264 |
| 35 | DNA strand elongation (GO:0022616) | 3.49066249 |
| 36 | regulation of centriole replication (GO:0046599) | 3.48552908 |
| 37 | establishment of integrated proviral latency (GO:0075713) | 3.46436308 |
| 38 | protein localization to chromosome, centromeric region (GO:0071459) | 3.45703672 |
| 39 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.44320457 |
| 40 | DNA replication-independent nucleosome organization (GO:0034724) | 3.42926503 |
| 41 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.42926503 |
| 42 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.40873339 |
| 43 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.40873339 |
| 44 | mitotic nuclear envelope disassembly (GO:0007077) | 3.39778179 |
| 45 | regulation of helicase activity (GO:0051095) | 3.38665756 |
| 46 | DNA ligation (GO:0006266) | 3.37971154 |
| 47 | nucleobase biosynthetic process (GO:0046112) | 3.36547349 |
| 48 | pore complex assembly (GO:0046931) | 3.36083158 |
| 49 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.34319361 |
| 50 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 3.31627948 |
| 51 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 3.31627948 |
| 52 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 3.31627948 |
| 53 | negative regulation of sister chromatid segregation (GO:0033046) | 3.31627948 |
| 54 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 3.31627948 |
| 55 | establishment of chromosome localization (GO:0051303) | 3.29193386 |
| 56 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.28981546 |
| 57 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.28981546 |
| 58 | isotype switching (GO:0045190) | 3.28981546 |
| 59 | negative regulation of chromosome segregation (GO:0051985) | 3.28505905 |
| 60 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.26456309 |
| 61 | negative regulation of ligase activity (GO:0051352) | 3.26456309 |
| 62 | kinetochore organization (GO:0051383) | 3.23747330 |
| 63 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 3.23609330 |
| 64 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 3.23609330 |
| 65 | histone H2A acetylation (GO:0043968) | 3.23459130 |
| 66 | mitotic recombination (GO:0006312) | 3.20299738 |
| 67 | spindle assembly checkpoint (GO:0071173) | 3.19393277 |
| 68 | protein K6-linked ubiquitination (GO:0085020) | 3.18691168 |
| 69 | mitotic spindle assembly checkpoint (GO:0007094) | 3.18642044 |
| 70 | synapsis (GO:0007129) | 3.18512282 |
| 71 | IMP metabolic process (GO:0046040) | 3.18001790 |
| 72 | regulation of chromosome segregation (GO:0051983) | 3.17982659 |
| 73 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.16602933 |
| 74 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.16179235 |
| 75 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.16179235 |
| 76 | telomere maintenance via recombination (GO:0000722) | 3.15779352 |
| 77 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.15398467 |
| 78 | negative regulation of DNA recombination (GO:0045910) | 3.15085056 |
| 79 | mitochondrial RNA metabolic process (GO:0000959) | 3.12957425 |
| 80 | regulation of mitotic sister chromatid separation (GO:0010965) | 3.11372998 |
| 81 | regulation of mitotic sister chromatid segregation (GO:0033047) | 3.11372998 |
| 82 | regulation of sister chromatid segregation (GO:0033045) | 3.11372998 |
| 83 | tRNA aminoacylation for protein translation (GO:0006418) | 3.10869530 |
| 84 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.10547803 |
| 85 | amino acid activation (GO:0043038) | 3.10490903 |
| 86 | tRNA aminoacylation (GO:0043039) | 3.10490903 |
| 87 | nuclear envelope disassembly (GO:0051081) | 3.09630623 |
| 88 | membrane disassembly (GO:0030397) | 3.09630623 |
| 89 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 3.07789630 |
| 90 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.06063845 |
| 91 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.03306407 |
| 92 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.03306407 |
| 93 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.03306407 |
| 94 | mitotic G2/M transition checkpoint (GO:0044818) | 2.99929261 |
| 95 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.99201148 |
| 96 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.99201148 |
| 97 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.98388831 |
| 98 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.96405537 |
| 99 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.92685131 |
| 100 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.92685131 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 6.60077171 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.51114148 |
| 3 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.86991302 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.46805771 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.92180011 |
| 6 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.87729149 |
| 7 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.80981380 |
| 8 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.76987458 |
| 9 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.75932834 |
| 10 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.70887556 |
| 11 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.69940403 |
| 12 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.51337721 |
| 13 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.49752234 |
| 14 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.44369187 |
| 15 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.37047284 |
| 16 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.35435000 |
| 17 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.26911124 |
| 18 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.22967709 |
| 19 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.20253658 |
| 20 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.18201263 |
| 21 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 2.16441268 |
| 22 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.14246661 |
| 23 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 2.12545731 |
| 24 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.07855326 |
| 25 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.97936679 |
| 26 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.94872266 |
| 27 | * POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.92721232 |
| 28 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.90001756 |
| 29 | FUS_26573619_Chip-Seq_HEK293_Human | 1.87757247 |
| 30 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.83096951 |
| 31 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.78080792 |
| 32 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.77921987 |
| 33 | EWS_26573619_Chip-Seq_HEK293_Human | 1.77038092 |
| 34 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.76963288 |
| 35 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.76228317 |
| 36 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.74177970 |
| 37 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.70384951 |
| 38 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.61236994 |
| 39 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.58028045 |
| 40 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.52327976 |
| 41 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.52306182 |
| 42 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.50976527 |
| 43 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.49200696 |
| 44 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.49133323 |
| 45 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.48882238 |
| 46 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.46381675 |
| 47 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.45973172 |
| 48 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.44214010 |
| 49 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.39379162 |
| 50 | * MYC_18940864_ChIP-ChIP_HL60_Human | 1.39309063 |
| 51 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.29805121 |
| 52 | VDR_22108803_ChIP-Seq_LS180_Human | 1.29575380 |
| 53 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.29319357 |
| 54 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.26166472 |
| 55 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.25709699 |
| 56 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.25527323 |
| 57 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.24075070 |
| 58 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.21751854 |
| 59 | P300_19829295_ChIP-Seq_ESCs_Human | 1.20420538 |
| 60 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.19484528 |
| 61 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.18176074 |
| 62 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.16580344 |
| 63 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.14555202 |
| 64 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.13087178 |
| 65 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.08912024 |
| 66 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.08378736 |
| 67 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.08014988 |
| 68 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.06140206 |
| 69 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.05158224 |
| 70 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.04534755 |
| 71 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.00922627 |
| 72 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.00603643 |
| 73 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.00046683 |
| 74 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 0.98259063 |
| 75 | * TFEB_21752829_ChIP-Seq_HELA_Human | 0.95851204 |
| 76 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.95719020 |
| 77 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.95605525 |
| 78 | * XRN2_22483619_ChIP-Seq_HELA_Human | 0.92666827 |
| 79 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.91354496 |
| 80 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.90495321 |
| 81 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.86879856 |
| 82 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.83146507 |
| 83 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.81909155 |
| 84 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.81418992 |
| 85 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.79936409 |
| 86 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.78904395 |
| 87 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.78896408 |
| 88 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.78325886 |
| 89 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.78283387 |
| 90 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.78227155 |
| 91 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.77882654 |
| 92 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.77453338 |
| 93 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.77142123 |
| 94 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.76415455 |
| 95 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.76370641 |
| 96 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 0.75770761 |
| 97 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.75653730 |
| 98 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.74041318 |
| 99 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 0.73119316 |
| 100 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.71809297 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0010094_abnormal_chromosome_stability | 4.30979275 |
| 2 | MP0008057_abnormal_DNA_replication | 4.21600029 |
| 3 | MP0008058_abnormal_DNA_repair | 4.05460334 |
| 4 | MP0000372_irregular_coat_pigmentation | 3.94849203 |
| 5 | MP0003693_abnormal_embryo_hatching | 3.83153637 |
| 6 | MP0002102_abnormal_ear_morphology | 3.51250925 |
| 7 | MP0004957_abnormal_blastocyst_morpholog | 3.50569848 |
| 8 | MP0003111_abnormal_nucleus_morphology | 3.27285080 |
| 9 | MP0003077_abnormal_cell_cycle | 3.04237639 |
| 10 | MP0009697_abnormal_copulation | 2.77272751 |
| 11 | MP0008932_abnormal_embryonic_tissue | 2.66548760 |
| 12 | MP0003806_abnormal_nucleotide_metabolis | 2.49677150 |
| 13 | MP0003890_abnormal_embryonic-extraembry | 2.49295613 |
| 14 | MP0008877_abnormal_DNA_methylation | 2.45257957 |
| 15 | MP0003718_maternal_effect | 2.33632421 |
| 16 | MP0008007_abnormal_cellular_replicative | 2.17812820 |
| 17 | MP0005075_abnormal_melanosome_morpholog | 2.15818444 |
| 18 | MP0005408_hypopigmentation | 2.10046500 |
| 19 | MP0005171_absent_coat_pigmentation | 2.09957749 |
| 20 | MP0000015_abnormal_ear_pigmentation | 1.73211412 |
| 21 | MP0003786_premature_aging | 1.72023423 |
| 22 | MP0002938_white_spotting | 1.69875380 |
| 23 | MP0003941_abnormal_skin_development | 1.63359125 |
| 24 | MP0003136_yellow_coat_color | 1.61720176 |
| 25 | MP0006036_abnormal_mitochondrial_physio | 1.51602585 |
| 26 | MP0001697_abnormal_embryo_size | 1.47792672 |
| 27 | MP0001293_anophthalmia | 1.44867537 |
| 28 | MP0001730_embryonic_growth_arrest | 1.43770966 |
| 29 | MP0000350_abnormal_cell_proliferation | 1.42220440 |
| 30 | MP0006035_abnormal_mitochondrial_morpho | 1.40639948 |
| 31 | MP0001672_abnormal_embryogenesis/_devel | 1.38104851 |
| 32 | MP0005380_embryogenesis_phenotype | 1.38104851 |
| 33 | MP0010352_gastrointestinal_tract_polyps | 1.32388347 |
| 34 | MP0001324_abnormal_eye_pigmentation | 1.30819379 |
| 35 | MP0003186_abnormal_redox_activity | 1.30794163 |
| 36 | MP0006054_spinal_hemorrhage | 1.29832652 |
| 37 | MP0002084_abnormal_developmental_patter | 1.29668100 |
| 38 | MP0002877_abnormal_melanocyte_morpholog | 1.27903975 |
| 39 | MP0010307_abnormal_tumor_latency | 1.24500644 |
| 40 | MP0003937_abnormal_limbs/digits/tail_de | 1.23610024 |
| 41 | MP0003646_muscle_fatigue | 1.23309048 |
| 42 | MP0000358_abnormal_cell_content/ | 1.19389240 |
| 43 | MP0003984_embryonic_growth_retardation | 1.18804145 |
| 44 | MP0002088_abnormal_embryonic_growth/wei | 1.16910153 |
| 45 | MP0003567_abnormal_fetal_cardiomyocyte | 1.14727701 |
| 46 | MP0000569_abnormal_digit_pigmentation | 1.12316020 |
| 47 | MP0003950_abnormal_plasma_membrane | 1.11985203 |
| 48 | MP0004147_increased_porphyrin_level | 1.11967264 |
| 49 | MP0002095_abnormal_skin_pigmentation | 1.11152746 |
| 50 | MP0001188_hyperpigmentation | 1.10854017 |
| 51 | MP0002080_prenatal_lethality | 1.10577057 |
| 52 | MP0000371_diluted_coat_color | 1.10206475 |
| 53 | MP0002085_abnormal_embryonic_tissue | 1.08381361 |
| 54 | MP0001529_abnormal_vocalization | 1.08325896 |
| 55 | MP0004197_abnormal_fetal_growth/weight/ | 1.06856215 |
| 56 | MP0005174_abnormal_tail_pigmentation | 1.05996553 |
| 57 | MP0000647_abnormal_sebaceous_gland | 1.05959141 |
| 58 | MP0004215_abnormal_myocardial_fiber | 1.05063997 |
| 59 | MP0003195_calcinosis | 1.05013503 |
| 60 | MP0000516_abnormal_urinary_system | 1.02019631 |
| 61 | MP0005367_renal/urinary_system_phenotyp | 1.02019631 |
| 62 | MP0003221_abnormal_cardiomyocyte_apopto | 1.00157645 |
| 63 | MP0001929_abnormal_gametogenesis | 0.96998459 |
| 64 | MP0001984_abnormal_olfaction | 0.95800211 |
| 65 | MP0009672_abnormal_birth_weight | 0.93983382 |
| 66 | MP0001661_extended_life_span | 0.92957102 |
| 67 | MP0000313_abnormal_cell_death | 0.92060739 |
| 68 | MP0003943_abnormal_hepatobiliary_system | 0.91150237 |
| 69 | MP0001286_abnormal_eye_development | 0.91058025 |
| 70 | MP0003119_abnormal_digestive_system | 0.88965676 |
| 71 | MP0002233_abnormal_nose_morphology | 0.88477458 |
| 72 | MP0005187_abnormal_penis_morphology | 0.86377133 |
| 73 | MP0008789_abnormal_olfactory_epithelium | 0.85837631 |
| 74 | MP0002090_abnormal_vision | 0.85602011 |
| 75 | MP0002086_abnormal_extraembryonic_tissu | 0.84650222 |
| 76 | MP0002160_abnormal_reproductive_system | 0.84510354 |
| 77 | MP0002210_abnormal_sex_determination | 0.82766144 |
| 78 | MP0005395_other_phenotype | 0.79914449 |
| 79 | MP0009703_decreased_birth_body | 0.77653974 |
| 80 | MP0005253_abnormal_eye_physiology | 0.77129544 |
| 81 | MP0004233_abnormal_muscle_weight | 0.76858851 |
| 82 | MP0005384_cellular_phenotype | 0.75498419 |
| 83 | MP0000653_abnormal_sex_gland | 0.75183927 |
| 84 | MP0002837_dystrophic_cardiac_calcinosis | 0.74280585 |
| 85 | MP0002751_abnormal_autonomic_nervous | 0.73079938 |
| 86 | MP0001145_abnormal_male_reproductive | 0.71597550 |
| 87 | MP0003137_abnormal_impulse_conducting | 0.70443129 |
| 88 | MP0004084_abnormal_cardiac_muscle | 0.68964209 |
| 89 | MP0002019_abnormal_tumor_incidence | 0.68829222 |
| 90 | MP0010030_abnormal_orbit_morphology | 0.67162822 |
| 91 | MP0003755_abnormal_palate_morphology | 0.66522364 |
| 92 | MP0001119_abnormal_female_reproductive | 0.66191220 |
| 93 | MP0010678_abnormal_skin_adnexa | 0.66145376 |
| 94 | MP0006292_abnormal_olfactory_placode | 0.65910211 |
| 95 | MP0005248_abnormal_Harderian_gland | 0.65291554 |
| 96 | MP0002234_abnormal_pharynx_morphology | 0.64978064 |
| 97 | MP0005394_taste/olfaction_phenotype | 0.64947957 |
| 98 | MP0005499_abnormal_olfactory_system | 0.64947957 |
| 99 | MP0003656_abnormal_erythrocyte_physiolo | 0.64929129 |
| 100 | MP0005266_abnormal_metabolism | 0.64080556 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 4.29256334 |
| 2 | Chromsome breakage (HP:0040012) | 4.14312413 |
| 3 | Abnormality of chromosome stability (HP:0003220) | 3.67695239 |
| 4 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 3.14219809 |
| 5 | Meckel diverticulum (HP:0002245) | 3.08913729 |
| 6 | Volvulus (HP:0002580) | 3.03711282 |
| 7 | Abnormal lung lobation (HP:0002101) | 2.93669116 |
| 8 | Ependymoma (HP:0002888) | 2.91924912 |
| 9 | Abnormality of the ileum (HP:0001549) | 2.91852819 |
| 10 | Abnormality of methionine metabolism (HP:0010901) | 2.90625749 |
| 11 | Birth length less than 3rd percentile (HP:0003561) | 2.89676463 |
| 12 | Abnormality of the preputium (HP:0100587) | 2.82879957 |
| 13 | Neoplasm of the adrenal gland (HP:0100631) | 2.79488310 |
| 14 | Rhabdomyosarcoma (HP:0002859) | 2.73162050 |
| 15 | Small intestinal stenosis (HP:0012848) | 2.71867004 |
| 16 | Duodenal stenosis (HP:0100867) | 2.71867004 |
| 17 | Glioma (HP:0009733) | 2.70562659 |
| 18 | Colon cancer (HP:0003003) | 2.67742260 |
| 19 | Abnormality of the astrocytes (HP:0100707) | 2.66053971 |
| 20 | Astrocytoma (HP:0009592) | 2.66053971 |
| 21 | Abnormality of the labia minora (HP:0012880) | 2.61857637 |
| 22 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.57791487 |
| 23 | Cortical dysplasia (HP:0002539) | 2.54149508 |
| 24 | Abnormal auditory evoked potentials (HP:0006958) | 2.51004635 |
| 25 | Medulloblastoma (HP:0002885) | 2.47112333 |
| 26 | Abnormality of glycolysis (HP:0004366) | 2.46329287 |
| 27 | Abnormality of the duodenum (HP:0002246) | 2.45905269 |
| 28 | Embryonal renal neoplasm (HP:0011794) | 2.45200858 |
| 29 | Bifid tongue (HP:0010297) | 2.42899933 |
| 30 | Methylmalonic acidemia (HP:0002912) | 2.41937946 |
| 31 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.39596094 |
| 32 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.39596094 |
| 33 | Abnormal protein glycosylation (HP:0012346) | 2.39596094 |
| 34 | Abnormal glycosylation (HP:0012345) | 2.39596094 |
| 35 | Sloping forehead (HP:0000340) | 2.36698561 |
| 36 | Increased hepatocellular lipid droplets (HP:0006565) | 2.35958114 |
| 37 | Type I transferrin isoform profile (HP:0003642) | 2.35911930 |
| 38 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.30987837 |
| 39 | Hypoplasia of the fovea (HP:0007750) | 2.23100935 |
| 40 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.23100935 |
| 41 | Neoplasm of the adrenal cortex (HP:0100641) | 2.22543380 |
| 42 | Lipid accumulation in hepatocytes (HP:0006561) | 2.22065701 |
| 43 | Increased CSF lactate (HP:0002490) | 2.21570945 |
| 44 | Progressive inability to walk (HP:0002505) | 2.19005638 |
| 45 | Abnormality of the anterior horn cell (HP:0006802) | 2.18434959 |
| 46 | Degeneration of anterior horn cells (HP:0002398) | 2.18434959 |
| 47 | Abnormality of serum amino acid levels (HP:0003112) | 2.17799387 |
| 48 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.16545210 |
| 49 | Abnormality of alanine metabolism (HP:0010916) | 2.16545210 |
| 50 | Hyperalaninemia (HP:0003348) | 2.16545210 |
| 51 | Myelodysplasia (HP:0002863) | 2.14977225 |
| 52 | Papillary thyroid carcinoma (HP:0002895) | 2.14943805 |
| 53 | Patchy hypopigmentation of hair (HP:0011365) | 2.09699740 |
| 54 | Neoplasm of the colon (HP:0100273) | 2.08808615 |
| 55 | Increased serum pyruvate (HP:0003542) | 2.08713251 |
| 56 | Hypoplastic pelvis (HP:0008839) | 2.07761271 |
| 57 | Acute encephalopathy (HP:0006846) | 2.05895417 |
| 58 | Abnormality of the fovea (HP:0000493) | 2.03295558 |
| 59 | Cerebral edema (HP:0002181) | 2.01535838 |
| 60 | Methylmalonic aciduria (HP:0012120) | 2.00193254 |
| 61 | Acute necrotizing encephalopathy (HP:0006965) | 1.98858534 |
| 62 | Increased serum lactate (HP:0002151) | 1.95757054 |
| 63 | Freckling (HP:0001480) | 1.94219075 |
| 64 | Postnatal microcephaly (HP:0005484) | 1.92469298 |
| 65 | Thyroid carcinoma (HP:0002890) | 1.92327753 |
| 66 | Intestinal atresia (HP:0011100) | 1.89882390 |
| 67 | Exercise-induced muscle cramps (HP:0003710) | 1.88087237 |
| 68 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.86182359 |
| 69 | Gonadotropin excess (HP:0000837) | 1.85828741 |
| 70 | Clubbing of toes (HP:0100760) | 1.85111566 |
| 71 | White forelock (HP:0002211) | 1.85057593 |
| 72 | Microvesicular hepatic steatosis (HP:0001414) | 1.84241198 |
| 73 | Absent radius (HP:0003974) | 1.80564234 |
| 74 | Proximal tubulopathy (HP:0000114) | 1.78735127 |
| 75 | Deep philtrum (HP:0002002) | 1.78355678 |
| 76 | Ovarian neoplasm (HP:0100615) | 1.77470616 |
| 77 | Abnormality of the carotid arteries (HP:0005344) | 1.76326030 |
| 78 | Renal Fanconi syndrome (HP:0001994) | 1.76276872 |
| 79 | Breast carcinoma (HP:0003002) | 1.76059223 |
| 80 | Astigmatism (HP:0000483) | 1.75886559 |
| 81 | Triphalangeal thumb (HP:0001199) | 1.75314165 |
| 82 | Long clavicles (HP:0000890) | 1.73831631 |
| 83 | Aplasia involving forearm bones (HP:0009822) | 1.73079932 |
| 84 | Absent forearm bone (HP:0003953) | 1.73079932 |
| 85 | Abnormality of homocysteine metabolism (HP:0010919) | 1.73023553 |
| 86 | Homocystinuria (HP:0002156) | 1.73023553 |
| 87 | Megaloblastic anemia (HP:0001889) | 1.72686806 |
| 88 | Medial flaring of the eyebrow (HP:0010747) | 1.72206269 |
| 89 | Progressive macrocephaly (HP:0004481) | 1.72134251 |
| 90 | Mitochondrial inheritance (HP:0001427) | 1.72091608 |
| 91 | Small hand (HP:0200055) | 1.71704976 |
| 92 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.71655420 |
| 93 | Cutaneous melanoma (HP:0012056) | 1.71427920 |
| 94 | Multiple enchondromatosis (HP:0005701) | 1.71357647 |
| 95 | Reduced antithrombin III activity (HP:0001976) | 1.69085330 |
| 96 | Albinism (HP:0001022) | 1.69022975 |
| 97 | Sensory axonal neuropathy (HP:0003390) | 1.68759206 |
| 98 | Increased nuchal translucency (HP:0010880) | 1.67751613 |
| 99 | Median cleft lip (HP:0000161) | 1.66104872 |
| 100 | Aplasia/Hypoplasia of the macula (HP:0008059) | 1.65454774 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TRIM28 | 4.16252436 |
| 2 | BUB1 | 3.39163781 |
| 3 | EIF2AK1 | 3.27867025 |
| 4 | PBK | 3.09698605 |
| 5 | NEK1 | 2.89226245 |
| 6 | WEE1 | 2.79547108 |
| 7 | SIK3 | 2.53769493 |
| 8 | MST4 | 2.53682477 |
| 9 | TTK | 2.52300037 |
| 10 | SRPK1 | 2.46957025 |
| 11 | EIF2AK3 | 2.39319475 |
| 12 | TSSK6 | 2.35675865 |
| 13 | BRSK2 | 2.30746946 |
| 14 | PLK3 | 2.29101060 |
| 15 | CDC7 | 2.28787461 |
| 16 | BCR | 2.22641048 |
| 17 | NUAK1 | 2.10861624 |
| 18 | WNK3 | 2.06284892 |
| 19 | ERBB3 | 1.91699525 |
| 20 | TAF1 | 1.89259257 |
| 21 | PLK4 | 1.82194293 |
| 22 | MKNK1 | 1.82139557 |
| 23 | ZAK | 1.77005009 |
| 24 | ACVR1B | 1.76133427 |
| 25 | PDK2 | 1.71741133 |
| 26 | MKNK2 | 1.70384351 |
| 27 | BMPR1B | 1.64545535 |
| 28 | PLK2 | 1.52197791 |
| 29 | PLK1 | 1.49170096 |
| 30 | FRK | 1.40387206 |
| 31 | STK3 | 1.32357561 |
| 32 | VRK2 | 1.32041176 |
| 33 | MAP4K2 | 1.31922207 |
| 34 | BRSK1 | 1.25740232 |
| 35 | ERBB4 | 1.24560469 |
| 36 | TNIK | 1.18323509 |
| 37 | STK38L | 1.16951222 |
| 38 | ATR | 1.13972871 |
| 39 | LATS1 | 1.11986429 |
| 40 | MAP3K12 | 1.06451158 |
| 41 | EIF2AK2 | 0.99233513 |
| 42 | RPS6KA4 | 0.97736959 |
| 43 | CHEK2 | 0.95061135 |
| 44 | CCNB1 | 0.94108174 |
| 45 | CSNK1G1 | 0.92374514 |
| 46 | CSNK1G3 | 0.87207228 |
| 47 | BRD4 | 0.86384613 |
| 48 | KSR1 | 0.83185965 |
| 49 | CSNK1A1L | 0.82870863 |
| 50 | CSNK1G2 | 0.80258482 |
| 51 | AURKB | 0.79365923 |
| 52 | ATM | 0.77485920 |
| 53 | CHEK1 | 0.76932298 |
| 54 | STK16 | 0.74653339 |
| 55 | STK39 | 0.70962837 |
| 56 | CLK1 | 0.70125701 |
| 57 | CDK7 | 0.68187891 |
| 58 | FER | 0.68008691 |
| 59 | STK10 | 0.65797754 |
| 60 | VRK1 | 0.64034763 |
| 61 | MAP3K4 | 0.63225470 |
| 62 | MARK3 | 0.63102967 |
| 63 | TGFBR1 | 0.61583911 |
| 64 | MELK | 0.57410338 |
| 65 | CDK9 | 0.55687962 |
| 66 | CASK | 0.54891994 |
| 67 | MAPK13 | 0.54476327 |
| 68 | NME1 | 0.50777725 |
| 69 | SCYL2 | 0.50474042 |
| 70 | STK24 | 0.50147757 |
| 71 | MAP2K7 | 0.49616386 |
| 72 | STK4 | 0.49297185 |
| 73 | DAPK1 | 0.49114252 |
| 74 | PINK1 | 0.47830897 |
| 75 | BCKDK | 0.46847692 |
| 76 | FLT3 | 0.45526649 |
| 77 | OXSR1 | 0.45109387 |
| 78 | DYRK3 | 0.44745963 |
| 79 | CDK3 | 0.43085819 |
| 80 | PASK | 0.42270385 |
| 81 | CSNK2A1 | 0.39984411 |
| 82 | YES1 | 0.39865350 |
| 83 | MINK1 | 0.39850199 |
| 84 | OBSCN | 0.37606664 |
| 85 | ALK | 0.36814109 |
| 86 | CDK1 | 0.36085321 |
| 87 | CDK6 | 0.34545296 |
| 88 | MST1R | 0.34064484 |
| 89 | PRKCE | 0.33772119 |
| 90 | RAF1 | 0.32086988 |
| 91 | MAP3K8 | 0.31867731 |
| 92 | CDK2 | 0.30831319 |
| 93 | MET | 0.30070289 |
| 94 | CSNK2A2 | 0.29553281 |
| 95 | CSNK1E | 0.29202979 |
| 96 | MAPKAPK5 | 0.28632056 |
| 97 | BMPR2 | 0.28171278 |
| 98 | NEK2 | 0.27804306 |
| 99 | PAK3 | 0.27780147 |
| 100 | PNCK | 0.26863348 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.18727513 |
| 2 | Mismatch repair_Homo sapiens_hsa03430 | 3.64366817 |
| 3 | Non-homologous end-joining_Homo sapiens_hsa03450 | 3.47691447 |
| 4 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 3.07510154 |
| 5 | DNA replication_Homo sapiens_hsa03030 | 3.04019840 |
| 6 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.03706243 |
| 7 | Protein export_Homo sapiens_hsa03060 | 2.85955852 |
| 8 | Homologous recombination_Homo sapiens_hsa03440 | 2.64949061 |
| 9 | Basal transcription factors_Homo sapiens_hsa03022 | 2.34816539 |
| 10 | RNA transport_Homo sapiens_hsa03013 | 2.32148366 |
| 11 | Cell cycle_Homo sapiens_hsa04110 | 2.26910670 |
| 12 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 2.26422081 |
| 13 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.23117296 |
| 14 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.13900761 |
| 15 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.09333341 |
| 16 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.94399442 |
| 17 | RNA polymerase_Homo sapiens_hsa03020 | 1.92452889 |
| 18 | Base excision repair_Homo sapiens_hsa03410 | 1.92012676 |
| 19 | RNA degradation_Homo sapiens_hsa03018 | 1.91576580 |
| 20 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.84744476 |
| 21 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.83150592 |
| 22 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.77898343 |
| 23 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.74789155 |
| 24 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.65260352 |
| 25 | Spliceosome_Homo sapiens_hsa03040 | 1.64956544 |
| 26 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.62869109 |
| 27 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.61334543 |
| 28 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.56115801 |
| 29 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.54783132 |
| 30 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.54260316 |
| 31 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.47236450 |
| 32 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.40142756 |
| 33 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.32530521 |
| 34 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.32081686 |
| 35 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.30961951 |
| 36 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.24689379 |
| 37 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.22881270 |
| 38 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.21964597 |
| 39 | Carbon metabolism_Homo sapiens_hsa01200 | 1.18644600 |
| 40 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.17645246 |
| 41 | Purine metabolism_Homo sapiens_hsa00230 | 1.16487554 |
| 42 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.14863147 |
| 43 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.12040779 |
| 44 | Parkinsons disease_Homo sapiens_hsa05012 | 1.05347486 |
| 45 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.00087633 |
| 46 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.98867444 |
| 47 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.95348122 |
| 48 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.87931067 |
| 49 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.86447503 |
| 50 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.81097166 |
| 51 | Huntingtons disease_Homo sapiens_hsa05016 | 0.79049699 |
| 52 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.77858487 |
| 53 | Peroxisome_Homo sapiens_hsa04146 | 0.75856741 |
| 54 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.75241871 |
| 55 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.73971519 |
| 56 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.73489970 |
| 57 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.70172435 |
| 58 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.67545321 |
| 59 | Metabolic pathways_Homo sapiens_hsa01100 | 0.62390307 |
| 60 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.60766149 |
| 61 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.59360688 |
| 62 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.58344680 |
| 63 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.57954438 |
| 64 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.56645231 |
| 65 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.56636121 |
| 66 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.56376461 |
| 67 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.55986402 |
| 68 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.53221788 |
| 69 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.51878099 |
| 70 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.51613903 |
| 71 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.47341588 |
| 72 | Thyroid cancer_Homo sapiens_hsa05216 | 0.43566633 |
| 73 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.41889698 |
| 74 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.41126121 |
| 75 | Adherens junction_Homo sapiens_hsa04520 | 0.40737239 |
| 76 | Alzheimers disease_Homo sapiens_hsa05010 | 0.40000084 |
| 77 | Circadian rhythm_Homo sapiens_hsa04710 | 0.39420356 |
| 78 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.38318319 |
| 79 | Lysine degradation_Homo sapiens_hsa00310 | 0.37052557 |
| 80 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.34950351 |
| 81 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.31596618 |
| 82 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.24817977 |
| 83 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.23462427 |
| 84 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.22954725 |
| 85 | Phototransduction_Homo sapiens_hsa04744 | 0.22385951 |
| 86 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.21717589 |
| 87 | Legionellosis_Homo sapiens_hsa05134 | 0.21325827 |
| 88 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.19665981 |
| 89 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.18182693 |
| 90 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.17612775 |
| 91 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.17386176 |
| 92 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.16452972 |
| 93 | Colorectal cancer_Homo sapiens_hsa05210 | 0.11211857 |
| 94 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.10199336 |
| 95 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.09646311 |
| 96 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.09407570 |
| 97 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.08707167 |
| 98 | Retinol metabolism_Homo sapiens_hsa00830 | 0.08006327 |
| 99 | Tight junction_Homo sapiens_hsa04530 | 0.06671736 |
| 100 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.06538696 |

