C6ORF10

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1melanin biosynthetic process (GO:0042438)9.43444854
2melanin metabolic process (GO:0006582)8.61184777
3secondary metabolite biosynthetic process (GO:0044550)8.06178400
4microtubule depolymerization (GO:0007019)6.22496899
5acrosome reaction (GO:0007340)6.07490692
6regulation of meiosis I (GO:0060631)5.85388304
7fusion of sperm to egg plasma membrane (GO:0007342)5.40744097
8attachment of spindle microtubules to kinetochore (GO:0008608)5.21545908
9response to pheromone (GO:0019236)5.15744680
10synapsis (GO:0007129)5.10796990
11regulation of DNA endoreduplication (GO:0032875)4.86533393
12microtubule polymerization or depolymerization (GO:0031109)4.85739918
13sperm motility (GO:0030317)4.81206623
14negative regulation of calcium ion-dependent exocytosis (GO:0045955)4.75911989
15ketone body metabolic process (GO:1902224)4.52687356
16developmental pigmentation (GO:0048066)4.48938292
17polyol catabolic process (GO:0046174)4.48245588
18phenol-containing compound biosynthetic process (GO:0046189)4.40964940
19centriole replication (GO:0007099)4.38710410
20single strand break repair (GO:0000012)4.37800122
21negative regulation of DNA-dependent DNA replication (GO:2000104)4.37613120
22inositol phosphate catabolic process (GO:0071545)4.28426730
23calcium ion-dependent exocytosis (GO:0017156)4.26154065
24plasma membrane fusion (GO:0045026)4.13671521
25retinal rod cell development (GO:0046548)4.09767344
26sister chromatid cohesion (GO:0007062)3.99943963
27piRNA metabolic process (GO:0034587)3.98887749
28RNA localization (GO:0006403)3.95532106
29intra-S DNA damage checkpoint (GO:0031573)3.94065089
30G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.89429244
31auditory receptor cell stereocilium organization (GO:0060088)3.85153517
32regulation of cilium movement (GO:0003352)3.77416605
33melanosome organization (GO:0032438)3.69344602
34microtubule anchoring (GO:0034453)3.64353570
35regulation of nuclear cell cycle DNA replication (GO:0033262)3.58831531
36pigment granule organization (GO:0048753)3.50570935
37chromosome organization involved in meiosis (GO:0070192)3.43956195
38phosphorylated carbohydrate dephosphorylation (GO:0046838)3.41038616
39inositol phosphate dephosphorylation (GO:0046855)3.41038616
40negative regulation of meiosis (GO:0045835)3.40933455
41reciprocal meiotic recombination (GO:0007131)3.40774937
42reciprocal DNA recombination (GO:0035825)3.40774937
43chromosome condensation (GO:0030261)3.37783838
44sympathetic nervous system development (GO:0048485)3.36415592
45DNA packaging (GO:0006323)3.36146498
46melanocyte differentiation (GO:0030318)3.33645416
47centrosome duplication (GO:0051298)3.32443490
48protein localization to kinetochore (GO:0034501)3.28925273
49regulation of centriole replication (GO:0046599)3.28736531
50detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.23036221
51pigment cell differentiation (GO:0050931)3.17532849
52DNA methylation involved in gamete generation (GO:0043046)3.14752103
53positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.14195044
54C4-dicarboxylate transport (GO:0015740)3.12748307
55seminiferous tubule development (GO:0072520)3.12468768
56spermatid development (GO:0007286)3.07236064
57male meiosis (GO:0007140)3.05827295
58short-term memory (GO:0007614)3.01022771
59oogenesis (GO:0048477)2.99238154
60histone exchange (GO:0043486)2.98786408
61inner ear receptor stereocilium organization (GO:0060122)2.98274169
62cell wall macromolecule metabolic process (GO:0044036)2.97284603
63centriole assembly (GO:0098534)2.96862038
64dopamine transport (GO:0015872)2.95657311
65epithelial cilium movement (GO:0003351)2.94674190
66postsynaptic membrane organization (GO:0001941)2.94121456
67male meiosis I (GO:0007141)2.93347278
68regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.91741018
69regulation of pigment cell differentiation (GO:0050932)2.89337914
70negative regulation of organelle assembly (GO:1902116)2.88321056
71telomere maintenance via telomerase (GO:0007004)2.87585378
72mitotic G2 DNA damage checkpoint (GO:0007095)2.84886643
73neuroepithelial cell differentiation (GO:0060563)2.82364541
74protein polyglutamylation (GO:0018095)2.81757215
75negative regulation of neurotransmitter transport (GO:0051589)2.77332878
76positive regulation of dendritic spine morphogenesis (GO:0061003)2.76263321
77neural tube formation (GO:0001841)2.75701764
78positive regulation of protein autophosphorylation (GO:0031954)2.75392404
79negative regulation of microtubule polymerization (GO:0031115)2.74477403
80epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.74055353
81cell wall macromolecule catabolic process (GO:0016998)2.72319146
82microtubule cytoskeleton organization involved in mitosis (GO:1902850)2.72020954
83spermatogenesis (GO:0007283)2.70909821
84male gamete generation (GO:0048232)2.70407763
85protein K11-linked deubiquitination (GO:0035871)2.69270215
86microtubule severing (GO:0051013)2.65459407
87microtubule nucleation (GO:0007020)2.65208709
88mitotic sister chromatid segregation (GO:0000070)2.64274379
89meiotic nuclear division (GO:0007126)2.63636026
90mitotic G2/M transition checkpoint (GO:0044818)2.62419495
91histone mRNA catabolic process (GO:0071044)2.60628121
92meiotic cell cycle process (GO:1903046)2.59153953
93recombinational repair (GO:0000725)2.58800818
94gamete generation (GO:0007276)2.58001457
95double-strand break repair via homologous recombination (GO:0000724)2.57129921
96regulation of DNA-dependent DNA replication (GO:0090329)2.56789585
97negative regulation of meiotic cell cycle (GO:0051447)2.56409231
98double-strand break repair via nonhomologous end joining (GO:0006303)2.55860380
99non-recombinational repair (GO:0000726)2.55860380
100presynaptic membrane assembly (GO:0097105)2.55000477

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.78379358
2ZNF274_21170338_ChIP-Seq_K562_Hela3.16853862
3GBX2_23144817_ChIP-Seq_PC3_Human3.06477340
4FUS_26573619_Chip-Seq_HEK293_Human2.85369785
5VDR_22108803_ChIP-Seq_LS180_Human2.75344776
6ZFP57_27257070_Chip-Seq_ESCs_Mouse2.56230805
7* CTBP1_25329375_ChIP-Seq_LNCAP_Human2.51674035
8FLI1_27457419_Chip-Seq_LIVER_Mouse2.45806251
9POU3F2_20337985_ChIP-ChIP_501MEL_Human2.43927802
10ER_23166858_ChIP-Seq_MCF-7_Human2.34238981
11TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.31386655
12E2F7_22180533_ChIP-Seq_HELA_Human2.26376671
13CTBP2_25329375_ChIP-Seq_LNCAP_Human2.23048452
14P300_19829295_ChIP-Seq_ESCs_Human2.17699732
15* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human2.05286846
16TAF15_26573619_Chip-Seq_HEK293_Human2.05220193
17PCGF2_27294783_Chip-Seq_ESCs_Mouse2.04953524
18MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.01436877
19SALL1_21062744_ChIP-ChIP_HESCs_Human1.96223747
20AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.94686855
21SMAD3_21741376_ChIP-Seq_EPCs_Human1.94469064
22CBP_20019798_ChIP-Seq_JUKART_Human1.90129318
23IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.90129318
24PCGF2_27294783_Chip-Seq_NPCs_Mouse1.88825153
25SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.86953360
26CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.85242844
27EZH2_22144423_ChIP-Seq_EOC_Human1.85005467
28TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.84441112
29POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.84441112
30SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.83531676
31AR_25329375_ChIP-Seq_VCAP_Human1.79653175
32SMAD4_21799915_ChIP-Seq_A2780_Human1.78449006
33SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.74293149
34GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.73915231
35PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.71657227
36EWS_26573619_Chip-Seq_HEK293_Human1.69326578
37STAT3_23295773_ChIP-Seq_U87_Human1.67381520
38SUZ12_27294783_Chip-Seq_NPCs_Mouse1.67239157
39CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.64982501
40NFE2_27457419_Chip-Seq_LIVER_Mouse1.63404579
41MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.60453419
42EZH2_27294783_Chip-Seq_NPCs_Mouse1.56670974
43SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.53108511
44TOP2B_26459242_ChIP-Seq_MCF-7_Human1.52421332
45TCF4_23295773_ChIP-Seq_U87_Human1.52214717
46TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.50911979
47AR_21572438_ChIP-Seq_LNCaP_Human1.50767945
48IGF1R_20145208_ChIP-Seq_DFB_Human1.49508277
49PIAS1_25552417_ChIP-Seq_VCAP_Human1.48756408
50OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.44998469
51RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.44021514
52ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.43599731
53TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.43562646
54RUNX2_22187159_ChIP-Seq_PCA_Human1.42199730
55NR3C1_21868756_ChIP-Seq_MCF10A_Human1.37794499
56GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.35918486
57TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.35585161
58SMAD3_21741376_ChIP-Seq_ESCs_Human1.35402062
59KLF5_20875108_ChIP-Seq_MESCs_Mouse1.35232966
60MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.32381786
61TCF4_18268006_ChIP-ChIP_LS174T_Human1.29085600
62NANOG_18555785_Chip-Seq_ESCs_Mouse1.29027768
63BCAT_22108803_ChIP-Seq_LS180_Human1.26085911
64GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.25284356
65* SMAD4_21741376_ChIP-Seq_EPCs_Human1.24759103
66TCF4_22108803_ChIP-Seq_LS180_Human1.23382572
67FOXM1_23109430_ChIP-Seq_U2OS_Human1.20700066
68CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.20495505
69E2F4_17652178_ChIP-ChIP_JURKAT_Human1.19735583
70LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19490305
71NANOG_19829295_ChIP-Seq_ESCs_Human1.18944667
72SOX2_19829295_ChIP-Seq_ESCs_Human1.18944667
73AUTS2_25519132_ChIP-Seq_293T-REX_Human1.18479878
74CMYC_18555785_Chip-Seq_ESCs_Mouse1.13933835
75DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.13366642
76E2F1_18555785_Chip-Seq_ESCs_Mouse1.12901866
77CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.10476004
78EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.10141273
79PRDM14_20953172_ChIP-Seq_ESCs_Human1.09359016
80P53_22387025_ChIP-Seq_ESCs_Mouse1.08922251
81ARNT_22903824_ChIP-Seq_MCF-7_Human1.06915537
82CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06865158
83SOX2_21211035_ChIP-Seq_LN229_Gbm1.05843921
84TP53_16413492_ChIP-PET_HCT116_Human1.05734487
85CRX_20693478_ChIP-Seq_RETINA_Mouse1.05615695
86SUZ12_18555785_Chip-Seq_ESCs_Mouse1.05477037
87TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.05380419
88OCT4_21477851_ChIP-Seq_ESCs_Mouse1.05191050
89OCT1_27270436_Chip-Seq_PROSTATE_Human1.05180196
90ETV1_20927104_ChIP-Seq_GIST48_Human1.04777303
91STAT3_18555785_Chip-Seq_ESCs_Mouse1.03390774
92TAL1_26923725_Chip-Seq_HPCs_Mouse1.02606970
93NFYA_21822215_ChIP-Seq_K562_Human1.01139168
94NFYB_21822215_ChIP-Seq_K562_Human1.01123418
95P300_18555785_Chip-Seq_ESCs_Mouse1.00362757
96KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human0.99414504
97KDM2B_26808549_Chip-Seq_REH_Human0.99223159
98OCT4_18555785_Chip-Seq_ESCs_Mouse0.99108471
99GATA3_21878914_ChIP-Seq_MCF-7_Human0.98224460
100ETV2_25802403_ChIP-Seq_MESCs_Mouse0.97871425

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000372_irregular_coat_pigmentation7.04831085
2MP0005171_absent_coat_pigmentation4.47188839
3MP0005408_hypopigmentation4.22715751
4MP0000015_abnormal_ear_pigmentation4.10345856
5MP0002102_abnormal_ear_morphology4.04939573
6MP0005075_abnormal_melanosome_morpholog3.75174083
7MP0003136_yellow_coat_color3.33895061
8MP0005410_abnormal_fertilization2.96036429
9MP0005377_hearing/vestibular/ear_phenot2.78106924
10MP0003878_abnormal_ear_physiology2.78106924
11MP0002095_abnormal_skin_pigmentation2.76423959
12MP0003950_abnormal_plasma_membrane2.73571483
13MP0003646_muscle_fatigue2.67699807
14MP0005174_abnormal_tail_pigmentation2.54769913
15MP0000371_diluted_coat_color2.53234786
16MP0000569_abnormal_digit_pigmentation2.39124134
17MP0008058_abnormal_DNA_repair2.35965297
18MP0001324_abnormal_eye_pigmentation2.24813093
19MP0008057_abnormal_DNA_replication2.22668834
20MP0003806_abnormal_nucleotide_metabolis2.13749742
21MP0010094_abnormal_chromosome_stability1.93079918
22MP0002090_abnormal_vision1.84598972
23MP0002938_white_spotting1.84304160
24MP0005551_abnormal_eye_electrophysiolog1.83045520
25MP0005253_abnormal_eye_physiology1.82213840
26MP0003787_abnormal_imprinting1.81244369
27MP0004381_abnormal_hair_follicle1.77573875
28MP0005257_abnormal_intraocular_pressure1.76745310
29MP0005670_abnormal_white_adipose1.73134034
30MP0006072_abnormal_retinal_apoptosis1.65722516
31MP0008877_abnormal_DNA_methylation1.65690371
32MP0002822_catalepsy1.64707764
33MP0003718_maternal_effect1.61390418
34MP0002736_abnormal_nociception_after1.51925802
35MP0006292_abnormal_olfactory_placode1.43407245
36MP0003698_abnormal_male_reproductive1.38322346
37MP0001501_abnormal_sleep_pattern1.37586318
38MP0001188_hyperpigmentation1.35137964
39MP0002075_abnormal_coat/hair_pigmentati1.32261051
40MP0005386_behavior/neurological_phenoty1.27098090
41MP0004924_abnormal_behavior1.27098090
42MP0002653_abnormal_ependyma_morphology1.23160754
43MP0001929_abnormal_gametogenesis1.23143087
44MP0001968_abnormal_touch/_nociception1.19739472
45MP0003880_abnormal_central_pattern1.18322830
46MP0001186_pigmentation_phenotype1.12367211
47MP0002234_abnormal_pharynx_morphology1.12325177
48MP0005248_abnormal_Harderian_gland1.11289314
49MP0003077_abnormal_cell_cycle1.09900850
50MP0009745_abnormal_behavioral_response1.06977850
51MP0005409_darkened_coat_color1.04056103
52MP0001984_abnormal_olfaction0.95275331
53MP0009046_muscle_twitch0.94008178
54MP0002638_abnormal_pupillary_reflex0.93315699
55MP0005187_abnormal_penis_morphology0.93302827
56MP0000427_abnormal_hair_cycle0.89454144
57MP0002272_abnormal_nervous_system0.88223644
58MP0000647_abnormal_sebaceous_gland0.85345174
59MP0001486_abnormal_startle_reflex0.84250345
60MP0005197_abnormal_uvea_morphology0.84045069
61MP0005391_vision/eye_phenotype0.83060804
62MP0002064_seizures0.82476018
63MP0005195_abnormal_posterior_eye0.79334377
64MP0005645_abnormal_hypothalamus_physiol0.77962049
65MP0002877_abnormal_melanocyte_morpholog0.77717341
66MP0008872_abnormal_physiological_respon0.75584708
67MP0002282_abnormal_trachea_morphology0.72642558
68MP0004885_abnormal_endolymph0.72577529
69MP0002229_neurodegeneration0.72143655
70MP0002210_abnormal_sex_determination0.69149667
71MP0001529_abnormal_vocalization0.69121706
72MP0005646_abnormal_pituitary_gland0.66194205
73MP0003121_genomic_imprinting0.65766262
74MP0001919_abnormal_reproductive_system0.63211390
75MP0003635_abnormal_synaptic_transmissio0.62511026
76MP0002752_abnormal_somatic_nervous0.62134012
77MP0002161_abnormal_fertility/fecundity0.61997762
78MP0000631_abnormal_neuroendocrine_gland0.61752665
79MP0003890_abnormal_embryonic-extraembry0.60259753
80MP0006276_abnormal_autonomic_nervous0.59961884
81MP0001293_anophthalmia0.59598898
82MP0000026_abnormal_inner_ear0.59407471
83MP0002396_abnormal_hematopoietic_system0.59335802
84MP0001485_abnormal_pinna_reflex0.59187553
85MP0002751_abnormal_autonomic_nervous0.58636135
86MP0002177_abnormal_outer_ear0.56983766
87MP0002735_abnormal_chemical_nociception0.54196579
88MP0002909_abnormal_adrenal_gland0.53526118
89MP0004085_abnormal_heartbeat0.53287143
90MP0002067_abnormal_sensory_capabilities0.51584447
91MP0008007_abnormal_cellular_replicative0.50682910
92MP0001963_abnormal_hearing_physiology0.50521439
93MP0004742_abnormal_vestibular_system0.50205509
94MP0002882_abnormal_neuron_morphology0.49441302
95MP0000955_abnormal_spinal_cord0.48694606
96MP0000653_abnormal_sex_gland0.48466431
97MP0004142_abnormal_muscle_tone0.48298798
98MP0004957_abnormal_blastocyst_morpholog0.46480019
99MP0004859_abnormal_synaptic_plasticity0.45440154
100MP0005389_reproductive_system_phenotype0.45106514

Predicted human phenotypes

RankGene SetZ-score
1Aplasia/Hypoplasia of the macula (HP:0008059)5.31453749
2Volvulus (HP:0002580)5.30962286
3Aplasia/Hypoplasia affecting the retina (HP:0008061)4.91218877
4Ocular albinism (HP:0001107)4.70234430
5Aplasia/Hypoplasia of the fovea (HP:0008060)4.61013043
6Hypoplasia of the fovea (HP:0007750)4.61013043
7Iris hypopigmentation (HP:0007730)4.42916589
8Hyperventilation (HP:0002883)4.21238580
9Blue irides (HP:0000635)4.00783737
10Abnormality of the fovea (HP:0000493)3.90190295
11Hypopigmentation of the fundus (HP:0007894)3.87129907
12White forelock (HP:0002211)3.57544527
13Generalized hypopigmentation (HP:0007513)3.55904639
14Congenital stationary night blindness (HP:0007642)3.51901690
15Patchy hypopigmentation of hair (HP:0011365)3.44835537
16Congenital sensorineural hearing impairment (HP:0008527)3.42160190
17Pancreatic cysts (HP:0001737)3.39854372
18Bifid tongue (HP:0010297)3.12935238
19Pancreatic fibrosis (HP:0100732)3.05089481
20Frequent falls (HP:0002359)3.04286303
21Astrocytoma (HP:0009592)3.02899363
22Abnormality of the astrocytes (HP:0100707)3.02899363
23True hermaphroditism (HP:0010459)2.97691140
24Cystic liver disease (HP:0006706)2.92925646
25Molar tooth sign on MRI (HP:0002419)2.87950887
26Abnormality of midbrain morphology (HP:0002418)2.87950887
27Freckling (HP:0001480)2.87780344
28Gaze-evoked nystagmus (HP:0000640)2.85449703
29Glioma (HP:0009733)2.83007382
30Astigmatism (HP:0000483)2.81918970
31Chromsome breakage (HP:0040012)2.78340793
32Decreased central vision (HP:0007663)2.70126062
33Abnormal auditory evoked potentials (HP:0006958)2.64309065
34Amblyopia (HP:0000646)2.62071084
35Horizontal nystagmus (HP:0000666)2.61419655
36Nephronophthisis (HP:0000090)2.55303500
37Albinism (HP:0001022)2.54866262
38Aplasia/Hypoplasia of the uvula (HP:0010293)2.53997282
39Absent speech (HP:0001344)2.51616031
40Chromosomal breakage induced by crosslinking agents (HP:0003221)2.50257758
41Severe visual impairment (HP:0001141)2.47978476
42Abnormality of the labia minora (HP:0012880)2.45282925
43Abnormality of macular pigmentation (HP:0008002)2.40259279
44Meckel diverticulum (HP:0002245)2.38913440
45Abnormality of the ileum (HP:0001549)2.36930905
46Abnormality of chromosome stability (HP:0003220)2.36888493
47Progressive cerebellar ataxia (HP:0002073)2.33636062
48Hypochromic microcytic anemia (HP:0004840)2.31699067
49Retinal dysplasia (HP:0007973)2.30336132
50Megalencephaly (HP:0001355)2.27565975
51Aplasia/Hypoplasia affecting the fundus (HP:0008057)2.25717447
52Small intestinal stenosis (HP:0012848)2.23557892
53Duodenal stenosis (HP:0100867)2.23557892
54Dynein arm defect of respiratory motile cilia (HP:0012255)2.22153610
55Absent/shortened dynein arms (HP:0200106)2.22153610
56Sloping forehead (HP:0000340)2.20313859
57Chronic hepatic failure (HP:0100626)2.20117110
58Hamartoma of the eye (HP:0010568)2.16474464
59Hypoplastic ischia (HP:0003175)2.16058442
60Bony spicule pigmentary retinopathy (HP:0007737)2.13898897
61Generalized hypopigmentation of hair (HP:0011358)2.12989348
62Focal motor seizures (HP:0011153)2.10611703
63Congenital hepatic fibrosis (HP:0002612)2.07876880
64Attenuation of retinal blood vessels (HP:0007843)2.04889987
65Abnormality of the renal medulla (HP:0100957)2.03820604
66Abnormality of the preputium (HP:0100587)2.02141382
67Ependymoma (HP:0002888)2.01783493
68Long clavicles (HP:0000890)2.01679709
69Cutaneous melanoma (HP:0012056)1.99446361
70Abnormality of chromosome segregation (HP:0002916)1.99281719
71Neuroendocrine neoplasm (HP:0100634)1.97639210
72Intestinal atresia (HP:0011100)1.96960773
73Small hand (HP:0200055)1.92679417
74Aplasia/Hypoplasia of the tongue (HP:0010295)1.91200906
75Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.91186176
76Clubbing of toes (HP:0100760)1.88338097
77Thickened helices (HP:0000391)1.87354789
78Sclerocornea (HP:0000647)1.87297451
79Photophobia (HP:0000613)1.83816610
80Facial cleft (HP:0002006)1.83316332
81Anencephaly (HP:0002323)1.82328882
82Widely spaced teeth (HP:0000687)1.82078438
83Cupped ear (HP:0000378)1.81457288
84Abnormality of the ischium (HP:0003174)1.80997305
85Oculomotor apraxia (HP:0000657)1.80823100
86Absent frontal sinuses (HP:0002688)1.80353350
87Inability to walk (HP:0002540)1.79524890
88Abnormality of the duodenum (HP:0002246)1.79197389
89Tented upper lip vermilion (HP:0010804)1.78685172
90Meningioma (HP:0002858)1.78413172
91Neoplasm of striated muscle (HP:0009728)1.77146527
92Limb dystonia (HP:0002451)1.76952953
93Abnormality of the nasal septum (HP:0000419)1.76078951
94Tachypnea (HP:0002789)1.75991632
95Renal dysplasia (HP:0000110)1.75936284
96Focal seizures (HP:0007359)1.74939210
97Fibular hypoplasia (HP:0003038)1.74738888
98Drooling (HP:0002307)1.73906119
99Neoplasm of the peripheral nervous system (HP:0100007)1.73786243
100Male pseudohermaphroditism (HP:0000037)1.72206477

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NEK14.29019461
2PLK44.14917328
3WNK33.99724652
4WEE13.82206730
5FRK3.42329505
6MARK13.29847486
7MAPK132.75089190
8PLK22.70421833
9NEK22.29447086
10PNCK2.28555345
11ACVR1B2.06004816
12MAP4K22.03414857
13INSRR1.84723661
14STK38L1.80106140
15PTK2B1.77736229
16PRKD31.75972163
17UHMK11.52552429
18BRD41.49794701
19AKT31.46368230
20PDK21.41551957
21SIK21.39638021
22MARK31.37838480
23STK31.29407444
24MST1R1.26134458
25BMPR21.25250044
26STK381.23373087
27CCNB11.20952624
28LATS11.19601828
29BMPR1B1.15573022
30BRSK21.13492359
31NUAK11.13436461
32ZAK1.10302166
33FGR1.08915073
34ADRBK21.07501289
35PLK31.01692881
36SRPK11.00148646
37PIK3CG0.99224546
38TRIM280.95448843
39BRSK10.89579117
40CSNK1G20.87103400
41ERBB20.80315261
42CASK0.80236254
43MKNK20.79897134
44GRK50.77755763
45EIF2AK10.76147862
46PRKCH0.75437515
47ERBB30.73786018
48CSNK1G30.73245251
49PKN10.72385896
50SIK30.72328829
51PRKCG0.71265944
52PBK0.70621304
53CAMK2A0.70153706
54TYK20.67467050
55BUB10.66466196
56YES10.65511640
57ATR0.65205162
58MAP3K120.65167506
59PLK10.63220681
60CDK70.62286691
61CSNK1G10.61386668
62PRKCE0.60440066
63EIF2AK30.58653196
64ATM0.58479708
65DDR20.58315923
66DYRK20.57909416
67DYRK1A0.54163932
68GRK70.53670961
69CDK30.53604485
70MINK10.53531625
71FGFR20.53411719
72CSNK1D0.52845071
73TNIK0.52763232
74GRK10.52483241
75CSNK1A1L0.52032927
76CHEK20.50569092
77PAK30.50360658
78CAMK1G0.49098953
79MET0.47695043
80ADRBK10.47499017
81CAMK40.47252648
82FER0.46979875
83CLK10.46877694
84SGK20.46797353
85CSNK1A10.46097606
86KIT0.45552190
87NTRK30.45369916
88NEK60.44891723
89CSF1R0.44803131
90PINK10.43520349
91PRKACB0.43154253
92CDC70.41973920
93TIE10.39663541
94FLT30.39002630
95CDK10.37951752
96DYRK30.37587854
97VRK10.37132986
98CAMK10.36939690
99PRKG10.36629725
100GSK3B0.36312581

Predicted pathways (KEGG)

RankGene SetZ-score
1Non-homologous end-joining_Homo sapiens_hsa034506.19936543
2Homologous recombination_Homo sapiens_hsa034404.30682819
3Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001303.16993901
4Mismatch repair_Homo sapiens_hsa034303.10793009
5Fanconi anemia pathway_Homo sapiens_hsa034602.82893953
6Protein export_Homo sapiens_hsa030602.50642825
7Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.49779907
8Phototransduction_Homo sapiens_hsa047442.11169989
9Propanoate metabolism_Homo sapiens_hsa006402.01309698
10Selenocompound metabolism_Homo sapiens_hsa004501.94000967
11Primary bile acid biosynthesis_Homo sapiens_hsa001201.86207122
12Basal transcription factors_Homo sapiens_hsa030221.83759358
13Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.77748551
14Nitrogen metabolism_Homo sapiens_hsa009101.75461748
15Nicotine addiction_Homo sapiens_hsa050331.72800398
16Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.72367174
17Olfactory transduction_Homo sapiens_hsa047401.66582534
18Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.65102088
19Collecting duct acid secretion_Homo sapiens_hsa049661.41220885
20Tyrosine metabolism_Homo sapiens_hsa003501.39295935
21Nucleotide excision repair_Homo sapiens_hsa034201.35386856
22DNA replication_Homo sapiens_hsa030301.35037350
23Taste transduction_Homo sapiens_hsa047421.32824168
24Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.31631863
25RNA degradation_Homo sapiens_hsa030181.29848069
26Fatty acid degradation_Homo sapiens_hsa000711.24927900
27Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.21316581
28Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.19152802
29Inositol phosphate metabolism_Homo sapiens_hsa005621.17528008
30Oocyte meiosis_Homo sapiens_hsa041141.13346101
31Butanoate metabolism_Homo sapiens_hsa006501.11328285
32Proteasome_Homo sapiens_hsa030501.10356856
33Fatty acid biosynthesis_Homo sapiens_hsa000611.08144305
34One carbon pool by folate_Homo sapiens_hsa006701.06315359
35Fatty acid metabolism_Homo sapiens_hsa012121.06148211
36Chemical carcinogenesis_Homo sapiens_hsa052041.02433941
37Tryptophan metabolism_Homo sapiens_hsa003800.97540286
38RNA transport_Homo sapiens_hsa030130.96010542
39Cell cycle_Homo sapiens_hsa041100.95986748
40Circadian rhythm_Homo sapiens_hsa047100.95738759
41Circadian entrainment_Homo sapiens_hsa047130.95702411
42Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.93335870
43Phosphatidylinositol signaling system_Homo sapiens_hsa040700.92721932
44Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.92388216
45RNA polymerase_Homo sapiens_hsa030200.91694545
46Parkinsons disease_Homo sapiens_hsa050120.89558592
47Synaptic vesicle cycle_Homo sapiens_hsa047210.87558531
48Glutamatergic synapse_Homo sapiens_hsa047240.85460204
49Dorso-ventral axis formation_Homo sapiens_hsa043200.84377196
50Huntingtons disease_Homo sapiens_hsa050160.83473496
51Sphingolipid metabolism_Homo sapiens_hsa006000.82118861
52Linoleic acid metabolism_Homo sapiens_hsa005910.80292871
53Glutathione metabolism_Homo sapiens_hsa004800.79887143
54Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.79635429
55Amphetamine addiction_Homo sapiens_hsa050310.79424634
56Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.78627592
57Glycerolipid metabolism_Homo sapiens_hsa005610.77745427
58beta-Alanine metabolism_Homo sapiens_hsa004100.74383097
59Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.71627951
60Morphine addiction_Homo sapiens_hsa050320.70548500
61Serotonergic synapse_Homo sapiens_hsa047260.67725927
62p53 signaling pathway_Homo sapiens_hsa041150.65797005
63Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.63722972
64Oxidative phosphorylation_Homo sapiens_hsa001900.63602988
65Insulin secretion_Homo sapiens_hsa049110.63515889
66Asthma_Homo sapiens_hsa053100.60990287
67Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.59691698
68Glycerophospholipid metabolism_Homo sapiens_hsa005640.57463415
69alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.57300974
70mRNA surveillance pathway_Homo sapiens_hsa030150.57226065
71Cocaine addiction_Homo sapiens_hsa050300.56474732
72Calcium signaling pathway_Homo sapiens_hsa040200.55013931
73Salivary secretion_Homo sapiens_hsa049700.54840258
74Base excision repair_Homo sapiens_hsa034100.54059964
75Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.53391720
76Caffeine metabolism_Homo sapiens_hsa002320.50275136
77Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.50205264
78Retinol metabolism_Homo sapiens_hsa008300.49625285
79Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.46650170
80Histidine metabolism_Homo sapiens_hsa003400.46550615
81Dopaminergic synapse_Homo sapiens_hsa047280.46143990
82Purine metabolism_Homo sapiens_hsa002300.45639994
83Ether lipid metabolism_Homo sapiens_hsa005650.44834324
84Metabolic pathways_Homo sapiens_hsa011000.43860204
85Pyrimidine metabolism_Homo sapiens_hsa002400.41645227
86Long-term depression_Homo sapiens_hsa047300.41197675
87ABC transporters_Homo sapiens_hsa020100.38369364
88GABAergic synapse_Homo sapiens_hsa047270.38345375
89Vitamin B6 metabolism_Homo sapiens_hsa007500.37061974
90Steroid hormone biosynthesis_Homo sapiens_hsa001400.36530071
91Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.35452233
92Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.33014715
93Melanoma_Homo sapiens_hsa052180.31872110
94SNARE interactions in vesicular transport_Homo sapiens_hsa041300.31607938
95TGF-beta signaling pathway_Homo sapiens_hsa043500.29033771
96Alzheimers disease_Homo sapiens_hsa050100.28228484
97cGMP-PKG signaling pathway_Homo sapiens_hsa040220.27974820
98Melanogenesis_Homo sapiens_hsa049160.27255890
99PPAR signaling pathway_Homo sapiens_hsa033200.25440105
100Allograft rejection_Homo sapiens_hsa053300.25153975

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »