

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.98534829 |
| 2 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.87395531 |
| 3 | positive regulation by symbiont of host defense response (GO:0052509) | 5.72051820 |
| 4 | modulation by symbiont of host defense response (GO:0052031) | 5.72051820 |
| 5 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.72051820 |
| 6 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.72051820 |
| 7 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.72051820 |
| 8 | modulation by symbiont of host immune response (GO:0052553) | 5.72051820 |
| 9 | negative regulation of cell killing (GO:0031342) | 5.55895933 |
| 10 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.55895933 |
| 11 | detection of molecule of bacterial origin (GO:0032490) | 5.38323456 |
| 12 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 5.15814220 |
| 13 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 4.94526472 |
| 14 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.92316448 |
| 15 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.90877962 |
| 16 | cellular extravasation (GO:0045123) | 4.81222254 |
| 17 | neutrophil mediated immunity (GO:0002446) | 4.74161187 |
| 18 | macrophage activation involved in immune response (GO:0002281) | 4.68037979 |
| 19 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.60431558 |
| 20 | detection of other organism (GO:0098543) | 4.54028414 |
| 21 | detection of external biotic stimulus (GO:0098581) | 4.49479515 |
| 22 | microglial cell activation (GO:0001774) | 4.37218148 |
| 23 | regulation of gamma-delta T cell activation (GO:0046643) | 4.30532596 |
| 24 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.27703454 |
| 25 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 4.19744765 |
| 26 | response to interleukin-15 (GO:0070672) | 4.16254644 |
| 27 | regulation of gamma-delta T cell differentiation (GO:0045586) | 4.13566658 |
| 28 | regulation of interferon-beta biosynthetic process (GO:0045357) | 4.12645088 |
| 29 | neutrophil activation involved in immune response (GO:0002283) | 4.06414371 |
| 30 | myeloid leukocyte mediated immunity (GO:0002444) | 4.06006421 |
| 31 | negative regulation of interleukin-12 production (GO:0032695) | 4.05784907 |
| 32 | neutrophil activation (GO:0042119) | 4.04543781 |
| 33 | detection of bacterium (GO:0016045) | 4.00079224 |
| 34 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.96146527 |
| 35 | response to host immune response (GO:0052572) | 3.96146527 |
| 36 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 3.90833191 |
| 37 | leukocyte migration involved in inflammatory response (GO:0002523) | 3.90517372 |
| 38 | detection of biotic stimulus (GO:0009595) | 3.90305961 |
| 39 | response to peptidoglycan (GO:0032494) | 3.88669134 |
| 40 | germinal center formation (GO:0002467) | 3.86172444 |
| 41 | macrophage activation (GO:0042116) | 3.74336874 |
| 42 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 3.70152631 |
| 43 | respiratory burst (GO:0045730) | 3.68044311 |
| 44 | cellular response to interleukin-15 (GO:0071350) | 3.65672714 |
| 45 | positive regulation of B cell differentiation (GO:0045579) | 3.63400498 |
| 46 | B cell receptor signaling pathway (GO:0050853) | 3.62717968 |
| 47 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 3.62230463 |
| 48 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 3.60272089 |
| 49 | leukocyte aggregation (GO:0070486) | 3.59875312 |
| 50 | negative regulation of B cell mediated immunity (GO:0002713) | 3.58531737 |
| 51 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 3.58531737 |
| 52 | response to host (GO:0075136) | 3.54537723 |
| 53 | response to host defenses (GO:0052200) | 3.54537723 |
| 54 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.54537723 |
| 55 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.53620883 |
| 56 | immunoglobulin mediated immune response (GO:0016064) | 3.52824135 |
| 57 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.51870424 |
| 58 | granulocyte activation (GO:0036230) | 3.49027114 |
| 59 | regulation of B cell differentiation (GO:0045577) | 3.48156534 |
| 60 | activated T cell proliferation (GO:0050798) | 3.47030487 |
| 61 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.45944511 |
| 62 | positive regulation of granulocyte differentiation (GO:0030854) | 3.45458513 |
| 63 | cilium or flagellum-dependent cell motility (GO:0001539) | 3.35749031 |
| 64 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.34275337 |
| 65 | myeloid cell activation involved in immune response (GO:0002275) | 3.32291730 |
| 66 | leukocyte degranulation (GO:0043299) | 3.23431969 |
| 67 | regulation of oxidative stress-induced neuron death (GO:1903203) | 3.20859185 |
| 68 | negative regulation of T cell mediated immunity (GO:0002710) | 3.20715703 |
| 69 | defense response to protozoan (GO:0042832) | 3.17310512 |
| 70 | T-helper 1 type immune response (GO:0042088) | 3.17089383 |
| 71 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.14950395 |
| 72 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.14950395 |
| 73 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.12494325 |
| 74 | regulation of interleukin-6 biosynthetic process (GO:0045408) | 3.07094766 |
| 75 | relaxation of smooth muscle (GO:0044557) | 3.04991964 |
| 76 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 3.03333623 |
| 77 | neutrophil chemotaxis (GO:0030593) | 3.01255506 |
| 78 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.97944088 |
| 79 | dendritic cell migration (GO:0036336) | 2.95417967 |
| 80 | regulation of tolerance induction (GO:0002643) | 2.93934807 |
| 81 | neutrophil migration (GO:1990266) | 2.93874538 |
| 82 | negative regulation of interleukin-6 production (GO:0032715) | 2.90747290 |
| 83 | regulation of mast cell degranulation (GO:0043304) | 2.90628395 |
| 84 | negative regulation of interleukin-1 production (GO:0032692) | 2.88094134 |
| 85 | negative T cell selection (GO:0043383) | 2.86282106 |
| 86 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 2.85007004 |
| 87 | positive thymic T cell selection (GO:0045059) | 2.84881030 |
| 88 | regulation of T cell mediated cytotoxicity (GO:0001914) | 2.84575078 |
| 89 | natural killer cell activation involved in immune response (GO:0002323) | 2.83641339 |
| 90 | negative regulation of adaptive immune response (GO:0002820) | 2.83322135 |
| 91 | negative thymic T cell selection (GO:0045060) | 2.83035393 |
| 92 | regulation of phosphoprotein phosphatase activity (GO:0043666) | 2.82476653 |
| 93 | regulation of T-helper 2 cell differentiation (GO:0045628) | 2.81413101 |
| 94 | positive regulation of tolerance induction (GO:0002645) | 2.80653775 |
| 95 | regulation of mast cell activation (GO:0033003) | 2.79966588 |
| 96 | tolerance induction (GO:0002507) | 2.78305044 |
| 97 | B cell mediated immunity (GO:0019724) | 2.77910145 |
| 98 | I-kappaB phosphorylation (GO:0007252) | 2.76910369 |
| 99 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 2.74910259 |
| 100 | positive regulation of catecholamine secretion (GO:0033605) | 2.74828771 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 8.37326069 |
| 2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.80382754 |
| 3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 4.66676478 |
| 4 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.56407308 |
| 5 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.26813097 |
| 6 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.94316428 |
| 7 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.84560803 |
| 8 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.80253458 |
| 9 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.80126577 |
| 10 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.79239201 |
| 11 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.68467668 |
| 12 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.57868152 |
| 13 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.57743674 |
| 14 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.45726226 |
| 15 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.34769557 |
| 16 | SPI1_23127762_ChIP-Seq_K562_Human | 2.17600772 |
| 17 | MYB_26560356_Chip-Seq_TH2_Human | 2.17354212 |
| 18 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 2.13131374 |
| 19 | MYB_26560356_Chip-Seq_TH1_Human | 2.08906729 |
| 20 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.07434110 |
| 21 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 2.05121770 |
| 22 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.99491472 |
| 23 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.95832298 |
| 24 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.93201798 |
| 25 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.92492860 |
| 26 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.79464213 |
| 27 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.77722979 |
| 28 | GATA3_26560356_Chip-Seq_TH2_Human | 1.77622619 |
| 29 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.69848021 |
| 30 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.66635693 |
| 31 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.65373598 |
| 32 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.64886059 |
| 33 | UTX_26944678_Chip-Seq_JUKART_Human | 1.64090492 |
| 34 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.58256634 |
| 35 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.54115995 |
| 36 | MAF_26560356_Chip-Seq_TH1_Human | 1.52340513 |
| 37 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.48635837 |
| 38 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.46459562 |
| 39 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.39105286 |
| 40 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.37303935 |
| 41 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.37020709 |
| 42 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.36526108 |
| 43 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.32987189 |
| 44 | MAF_26560356_Chip-Seq_TH2_Human | 1.32743041 |
| 45 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.30513473 |
| 46 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.26765032 |
| 47 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.26765032 |
| 48 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.25356008 |
| 49 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.24944633 |
| 50 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.22707194 |
| 51 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.21035124 |
| 52 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.13161273 |
| 53 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.11617092 |
| 54 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.10895184 |
| 55 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.07764827 |
| 56 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.06801119 |
| 57 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.06598991 |
| 58 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.06516270 |
| 59 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.06400947 |
| 60 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.02855080 |
| 61 | GATA3_26560356_Chip-Seq_TH1_Human | 1.02406833 |
| 62 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.97890071 |
| 63 | OCT1_27270436_Chip-Seq_PROSTATE_Human | 0.96091020 |
| 64 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 0.96043387 |
| 65 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.95959418 |
| 66 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.95659223 |
| 67 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.95481835 |
| 68 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.95481835 |
| 69 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.94443839 |
| 70 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.92571286 |
| 71 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.92559581 |
| 72 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.92398746 |
| 73 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.91688922 |
| 74 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.90469573 |
| 75 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.90154673 |
| 76 | PU_27001747_Chip-Seq_BMDM_Mouse | 0.88062668 |
| 77 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.87484152 |
| 78 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.87363521 |
| 79 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.86912161 |
| 80 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.86151178 |
| 81 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.84992098 |
| 82 | BCL6_25482012_ChIP-Seq_CML-JURL-MK1_Human | 0.83371576 |
| 83 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.82135944 |
| 84 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.82135349 |
| 85 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.81891373 |
| 86 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.80986175 |
| 87 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.80808914 |
| 88 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.79676199 |
| 89 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.79456300 |
| 90 | P300_27268052_Chip-Seq_Bcells_Human | 0.79438921 |
| 91 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.79148370 |
| 92 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.78989194 |
| 93 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.76626695 |
| 94 | OCT4_20526341_ChIP-Seq_ESCs_Human | 0.75964403 |
| 95 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.75174516 |
| 96 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.75167633 |
| 97 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.75162025 |
| 98 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.74856058 |
| 99 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.74107890 |
| 100 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.73116794 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003724_increased_susceptibility_to | 5.38975509 |
| 2 | MP0001835_abnormal_antigen_presentation | 3.98669874 |
| 3 | MP0003436_decreased_susceptibility_to | 3.53482706 |
| 4 | MP0003303_peritoneal_inflammation | 3.10159581 |
| 5 | MP0002132_abnormal_respiratory_system | 2.99893595 |
| 6 | MP0001800_abnormal_humoral_immune | 2.82975856 |
| 7 | MP0005410_abnormal_fertilization | 2.79889063 |
| 8 | MP0002419_abnormal_innate_immunity | 2.72712210 |
| 9 | MP0008004_abnormal_stomach_pH | 2.71186534 |
| 10 | MP0009785_altered_susceptibility_to | 2.58111328 |
| 11 | MP0005025_abnormal_response_to | 2.54886151 |
| 12 | MP0000015_abnormal_ear_pigmentation | 2.52821000 |
| 13 | MP0002723_abnormal_immune_serum | 2.46954027 |
| 14 | MP0002420_abnormal_adaptive_immunity | 2.44777791 |
| 15 | MP0005000_abnormal_immune_tolerance | 2.42950800 |
| 16 | MP0001819_abnormal_immune_cell | 2.42537902 |
| 17 | MP0005671_abnormal_response_to | 2.37339591 |
| 18 | MP0002452_abnormal_antigen_presenting | 2.33802828 |
| 19 | MP0005075_abnormal_melanosome_morpholog | 2.27281244 |
| 20 | MP0000685_abnormal_immune_system | 2.21242422 |
| 21 | MP0008260_abnormal_autophagy | 2.21027235 |
| 22 | MP0001790_abnormal_immune_system | 2.17671645 |
| 23 | MP0005387_immune_system_phenotype | 2.17671645 |
| 24 | MP0003763_abnormal_thymus_physiology | 2.17575109 |
| 25 | MP0004381_abnormal_hair_follicle | 2.15270330 |
| 26 | MP0000465_gastrointestinal_hemorrhage | 2.03653203 |
| 27 | MP0002277_abnormal_respiratory_mucosa | 1.94917850 |
| 28 | MP0003806_abnormal_nucleotide_metabolis | 1.93870265 |
| 29 | MP0000569_abnormal_digit_pigmentation | 1.90612475 |
| 30 | MP0002405_respiratory_system_inflammati | 1.89252338 |
| 31 | MP0002398_abnormal_bone_marrow | 1.84744307 |
| 32 | MP0003172_abnormal_lysosome_physiology | 1.80531166 |
| 33 | MP0000716_abnormal_immune_system | 1.78121110 |
| 34 | MP0005464_abnormal_platelet_physiology | 1.77171028 |
| 35 | MP0003828_pulmonary_edema | 1.69913840 |
| 36 | MP0006082_CNS_inflammation | 1.69012752 |
| 37 | MP0004883_abnormal_blood_vessel | 1.64264924 |
| 38 | MP0001533_abnormal_skeleton_physiology | 1.62312740 |
| 39 | MP0002148_abnormal_hypersensitivity_rea | 1.59200764 |
| 40 | MP0001845_abnormal_inflammatory_respons | 1.59174293 |
| 41 | MP0003300_gastrointestinal_ulcer | 1.52478324 |
| 42 | MP0000689_abnormal_spleen_morphology | 1.50030171 |
| 43 | MP0005451_abnormal_body_composition | 1.48455175 |
| 44 | MP0002396_abnormal_hematopoietic_system | 1.47599284 |
| 45 | MP0002722_abnormal_immune_system | 1.47208666 |
| 46 | MP0001986_abnormal_taste_sensitivity | 1.46023495 |
| 47 | MP0010155_abnormal_intestine_physiology | 1.44451569 |
| 48 | MP0003866_abnormal_defecation | 1.44285777 |
| 49 | MP0003045_fibrosis | 1.39006257 |
| 50 | MP0000703_abnormal_thymus_morphology | 1.38368370 |
| 51 | MP0009764_decreased_sensitivity_to | 1.37920349 |
| 52 | MP0002429_abnormal_blood_cell | 1.35580670 |
| 53 | MP0002166_altered_tumor_susceptibility | 1.13399088 |
| 54 | MP0003191_abnormal_cellular_cholesterol | 1.10851097 |
| 55 | MP0008469_abnormal_protein_level | 1.10324892 |
| 56 | MP0004947_skin_inflammation | 1.08943157 |
| 57 | MP0005164_abnormal_response_to | 1.05144090 |
| 58 | MP0003075_altered_response_to | 1.04374656 |
| 59 | MP0005174_abnormal_tail_pigmentation | 1.04002545 |
| 60 | MP0005310_abnormal_salivary_gland | 0.99934192 |
| 61 | MP0000858_altered_metastatic_potential | 0.98695549 |
| 62 | MP0001188_hyperpigmentation | 0.93725858 |
| 63 | MP0004484_altered_response_of | 0.91724114 |
| 64 | MP0003656_abnormal_erythrocyte_physiolo | 0.90238414 |
| 65 | MP0002332_abnormal_exercise_endurance | 0.87236814 |
| 66 | MP0003698_abnormal_male_reproductive | 0.84661891 |
| 67 | MP0001929_abnormal_gametogenesis | 0.84153140 |
| 68 | MP0005166_decreased_susceptibility_to | 0.81000468 |
| 69 | MP0001984_abnormal_olfaction | 0.79823436 |
| 70 | MP0009333_abnormal_splenocyte_physiolog | 0.78045743 |
| 71 | MP0002998_abnormal_bone_remodeling | 0.77295444 |
| 72 | MP0000343_altered_response_to | 0.76460756 |
| 73 | MP0005376_homeostasis/metabolism_phenot | 0.73449501 |
| 74 | MP0009278_abnormal_bone_marrow | 0.72917553 |
| 75 | MP0003183_abnormal_peptide_metabolism | 0.72915168 |
| 76 | MP0000371_diluted_coat_color | 0.69574629 |
| 77 | MP0005266_abnormal_metabolism | 0.66666657 |
| 78 | MP0001663_abnormal_digestive_system | 0.66134694 |
| 79 | MP0009763_increased_sensitivity_to | 0.64858792 |
| 80 | MP0002006_tumorigenesis | 0.62976410 |
| 81 | MP0002928_abnormal_bile_duct | 0.61838000 |
| 82 | MP0004808_abnormal_hematopoietic_stem | 0.61726058 |
| 83 | MP0002009_preneoplasia | 0.61303983 |
| 84 | MP0002095_abnormal_skin_pigmentation | 0.61024435 |
| 85 | MP0001545_abnormal_hematopoietic_system | 0.60690606 |
| 86 | MP0005397_hematopoietic_system_phenotyp | 0.60690606 |
| 87 | MP0001529_abnormal_vocalization | 0.58730141 |
| 88 | MP0004084_abnormal_cardiac_muscle | 0.58320594 |
| 89 | MP0008995_early_reproductive_senescence | 0.58152420 |
| 90 | MP0001664_abnormal_digestion | 0.57846682 |
| 91 | MP0008874_decreased_physiological_sensi | 0.56828806 |
| 92 | MP0001851_eye_inflammation | 0.56645455 |
| 93 | MP0000249_abnormal_blood_vessel | 0.53262026 |
| 94 | MP0009765_abnormal_xenobiotic_induced | 0.52951122 |
| 95 | MP0003221_abnormal_cardiomyocyte_apopto | 0.52734370 |
| 96 | MP0005377_hearing/vestibular/ear_phenot | 0.52711392 |
| 97 | MP0003878_abnormal_ear_physiology | 0.52711392 |
| 98 | MP0002019_abnormal_tumor_incidence | 0.48595027 |
| 99 | MP0002693_abnormal_pancreas_physiology | 0.48460763 |
| 100 | MP0005058_abnormal_lysosome_morphology | 0.48453175 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Myositis (HP:0100614) | 5.61975053 |
| 2 | Retrobulbar optic neuritis (HP:0100654) | 5.59634843 |
| 3 | Optic neuritis (HP:0100653) | 5.59634843 |
| 4 | Orchitis (HP:0100796) | 5.50245796 |
| 5 | Recurrent abscess formation (HP:0002722) | 5.37073933 |
| 6 | Recurrent bacterial skin infections (HP:0005406) | 5.31802094 |
| 7 | Eczematoid dermatitis (HP:0000976) | 5.23332620 |
| 8 | Stomatitis (HP:0010280) | 4.47044333 |
| 9 | Gastrointestinal infarctions (HP:0005244) | 4.38369059 |
| 10 | Keratoconjunctivitis sicca (HP:0001097) | 4.13723141 |
| 11 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.11514402 |
| 12 | Absent/shortened dynein arms (HP:0200106) | 3.96511706 |
| 13 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.96511706 |
| 14 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.87255294 |
| 15 | Keratoconjunctivitis (HP:0001096) | 3.78241544 |
| 16 | Encephalitis (HP:0002383) | 3.73893133 |
| 17 | Obstructive lung disease (HP:0006536) | 3.69471107 |
| 18 | Chronic obstructive pulmonary disease (HP:0006510) | 3.69471107 |
| 19 | Meningitis (HP:0001287) | 3.67598084 |
| 20 | Recurrent fungal infections (HP:0002841) | 3.67463067 |
| 21 | Abnormality of macrophages (HP:0004311) | 3.65619127 |
| 22 | Mediastinal lymphadenopathy (HP:0100721) | 3.53016205 |
| 23 | Recurrent skin infections (HP:0001581) | 3.38871556 |
| 24 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.33884263 |
| 25 | Vasculitis (HP:0002633) | 3.24001802 |
| 26 | Inflammation of the large intestine (HP:0002037) | 3.17747051 |
| 27 | Hemoptysis (HP:0002105) | 3.14623113 |
| 28 | Gingivitis (HP:0000230) | 3.13583030 |
| 29 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.11500767 |
| 30 | Recurrent cutaneous fungal infections (HP:0011370) | 3.11500767 |
| 31 | Chest pain (HP:0100749) | 3.08922731 |
| 32 | Abnormal ciliary motility (HP:0012262) | 3.08032435 |
| 33 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 3.04934304 |
| 34 | Resting tremor (HP:0002322) | 3.04723651 |
| 35 | T lymphocytopenia (HP:0005403) | 3.03657632 |
| 36 | Spontaneous hematomas (HP:0007420) | 3.03275766 |
| 37 | Arterial thrombosis (HP:0004420) | 3.01221452 |
| 38 | Abnormality of T cell number (HP:0011839) | 3.01010144 |
| 39 | Colitis (HP:0002583) | 2.96764092 |
| 40 | Gastrointestinal inflammation (HP:0004386) | 2.95495481 |
| 41 | Urticaria (HP:0001025) | 2.95007975 |
| 42 | Anorexia (HP:0002039) | 2.94025865 |
| 43 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.91443160 |
| 44 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.86969193 |
| 45 | Recurrent sinusitis (HP:0011108) | 2.86550505 |
| 46 | Nasal polyposis (HP:0100582) | 2.75467384 |
| 47 | Prolonged bleeding time (HP:0003010) | 2.74682865 |
| 48 | Postural instability (HP:0002172) | 2.73473168 |
| 49 | Peritonitis (HP:0002586) | 2.71871367 |
| 50 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.71023855 |
| 51 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.71023855 |
| 52 | Pulmonary embolism (HP:0002204) | 2.69794916 |
| 53 | Pulmonary infiltrates (HP:0002113) | 2.66669864 |
| 54 | Gingival bleeding (HP:0000225) | 2.61904860 |
| 55 | Gangrene (HP:0100758) | 2.60569155 |
| 56 | Panhypogammaglobulinemia (HP:0003139) | 2.58316765 |
| 57 | Leukocytosis (HP:0001974) | 2.51598972 |
| 58 | Acute hepatic failure (HP:0006554) | 2.47636652 |
| 59 | Abnormality of T cells (HP:0002843) | 2.42956185 |
| 60 | Abnormality of the columella (HP:0009929) | 2.42094794 |
| 61 | IgM deficiency (HP:0002850) | 2.40427149 |
| 62 | Polyneuropathy (HP:0001271) | 2.40301429 |
| 63 | Increased IgE level (HP:0003212) | 2.36274591 |
| 64 | Pustule (HP:0200039) | 2.35892317 |
| 65 | Granulocytopenia (HP:0001913) | 2.34726498 |
| 66 | Abnormality of the pleura (HP:0002103) | 2.32590219 |
| 67 | Hypochromic anemia (HP:0001931) | 2.31966530 |
| 68 | Chronic otitis media (HP:0000389) | 2.30537213 |
| 69 | Abnormality of the endocardium (HP:0004306) | 2.28839502 |
| 70 | Hypochromic microcytic anemia (HP:0004840) | 2.23970390 |
| 71 | Eosinophilia (HP:0001880) | 2.22429547 |
| 72 | Episodic fever (HP:0001954) | 2.21358361 |
| 73 | Epistaxis (HP:0000421) | 2.20714160 |
| 74 | Bronchiectasis (HP:0002110) | 2.17947037 |
| 75 | Abnormality of the peritoneum (HP:0002585) | 2.13790365 |
| 76 | Recurrent viral infections (HP:0004429) | 2.12814844 |
| 77 | Abnormality of the nasal mucosa (HP:0000433) | 2.11291287 |
| 78 | Cellulitis (HP:0100658) | 2.11026893 |
| 79 | Abnormal sex determination (HP:0012244) | 2.03490337 |
| 80 | Sex reversal (HP:0012245) | 2.03490337 |
| 81 | Facial diplegia (HP:0001349) | 2.01978059 |
| 82 | Recurrent bronchitis (HP:0002837) | 2.00238139 |
| 83 | Keratitis (HP:0000491) | 1.99678089 |
| 84 | Microcytic anemia (HP:0001935) | 1.96020388 |
| 85 | Osteomyelitis (HP:0002754) | 1.95271132 |
| 86 | Papilledema (HP:0001085) | 1.93536422 |
| 87 | Sepsis (HP:0100806) | 1.93043533 |
| 88 | Abnormality of T cell physiology (HP:0011840) | 1.89861323 |
| 89 | Ocular albinism (HP:0001107) | 1.88816881 |
| 90 | Glomerulopathy (HP:0100820) | 1.88310643 |
| 91 | Lymphopenia (HP:0001888) | 1.86245821 |
| 92 | Abnormality of eosinophils (HP:0001879) | 1.86235815 |
| 93 | Viral hepatitis (HP:0006562) | 1.85377189 |
| 94 | Chronic sinusitis (HP:0011109) | 1.83995148 |
| 95 | Hypoplasia of the uterus (HP:0000013) | 1.83835201 |
| 96 | Stomach cancer (HP:0012126) | 1.81963823 |
| 97 | Vertigo (HP:0002321) | 1.77780278 |
| 98 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.74837378 |
| 99 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.73400105 |
| 100 | Amaurosis fugax (HP:0100576) | 1.72531577 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | PINK1 | 4.27207307 |
| 2 | RIPK4 | 3.83867439 |
| 3 | TAOK3 | 3.34257737 |
| 4 | MARK3 | 3.33449997 |
| 5 | MAP4K1 | 3.09038104 |
| 6 | IRAK4 | 3.02288548 |
| 7 | FES | 2.73574230 |
| 8 | BLK | 2.70583295 |
| 9 | STK16 | 2.46724518 |
| 10 | CSK | 2.27897546 |
| 11 | MAP2K3 | 2.22125568 |
| 12 | TYK2 | 2.21136615 |
| 13 | TXK | 2.17069827 |
| 14 | GRK6 | 2.10314790 |
| 15 | EPHB1 | 2.03468200 |
| 16 | HCK | 1.90992788 |
| 17 | TNK2 | 1.89473154 |
| 18 | BTK | 1.85216024 |
| 19 | KSR2 | 1.78375808 |
| 20 | SYK | 1.71354613 |
| 21 | ZAP70 | 1.65827040 |
| 22 | JAK2 | 1.58244743 |
| 23 | IKBKE | 1.55664125 |
| 24 | FGR | 1.52964684 |
| 25 | TAOK1 | 1.39971428 |
| 26 | TLK1 | 1.39959051 |
| 27 | IRAK1 | 1.35034710 |
| 28 | PIK3CG | 1.28768979 |
| 29 | ITK | 1.28399054 |
| 30 | JAK3 | 1.27793940 |
| 31 | FRK | 1.21534915 |
| 32 | IRAK2 | 1.20819147 |
| 33 | LYN | 1.20488568 |
| 34 | MAP3K6 | 1.20262879 |
| 35 | MAP3K13 | 1.20180337 |
| 36 | MAP3K1 | 1.19111178 |
| 37 | MAP3K14 | 1.16606341 |
| 38 | MAP3K3 | 1.12509220 |
| 39 | LCK | 1.04759914 |
| 40 | TEC | 1.04136474 |
| 41 | ZAK | 1.04065509 |
| 42 | RAF1 | 1.03835304 |
| 43 | STK38 | 1.03554451 |
| 44 | MAP3K5 | 0.96406659 |
| 45 | JAK1 | 0.90455879 |
| 46 | ERN1 | 0.90236133 |
| 47 | LRRK2 | 0.89980955 |
| 48 | KIT | 0.88195951 |
| 49 | KSR1 | 0.86239494 |
| 50 | PRKCQ | 0.83817869 |
| 51 | RPS6KA5 | 0.83539008 |
| 52 | MARK2 | 0.81128656 |
| 53 | MAP2K6 | 0.76584494 |
| 54 | SIK2 | 0.74198002 |
| 55 | MAP3K2 | 0.74000605 |
| 56 | CSF1R | 0.73178361 |
| 57 | PTK2B | 0.72864207 |
| 58 | MAP3K11 | 0.70533770 |
| 59 | MAPK12 | 0.70312524 |
| 60 | YES1 | 0.69713538 |
| 61 | MAP3K7 | 0.69585905 |
| 62 | PDK1 | 0.68870810 |
| 63 | PAK3 | 0.67394417 |
| 64 | MAP2K4 | 0.66085246 |
| 65 | CDK12 | 0.65871991 |
| 66 | MATK | 0.59976700 |
| 67 | RET | 0.59865083 |
| 68 | TBK1 | 0.59241530 |
| 69 | BRD4 | 0.58648544 |
| 70 | FGFR3 | 0.58303955 |
| 71 | PIM1 | 0.55796492 |
| 72 | STK11 | 0.52249609 |
| 73 | PDPK1 | 0.51942932 |
| 74 | CDC42BPA | 0.48105986 |
| 75 | PRKCZ | 0.47276391 |
| 76 | BMPR2 | 0.45857115 |
| 77 | FYN | 0.45762100 |
| 78 | DAPK2 | 0.45368700 |
| 79 | WNK1 | 0.44737585 |
| 80 | IKBKB | 0.42751244 |
| 81 | NLK | 0.42029471 |
| 82 | MAPK7 | 0.40938128 |
| 83 | STK10 | 0.39988763 |
| 84 | EGFR | 0.39203092 |
| 85 | SIK3 | 0.38242418 |
| 86 | SGK2 | 0.37150057 |
| 87 | SGK223 | 0.36990792 |
| 88 | SGK494 | 0.36990792 |
| 89 | MAP4K2 | 0.35908898 |
| 90 | EEF2K | 0.33848433 |
| 91 | MAPKAPK3 | 0.33625779 |
| 92 | PTK6 | 0.33269905 |
| 93 | DYRK1A | 0.30255500 |
| 94 | CAMKK2 | 0.29814607 |
| 95 | ERBB3 | 0.29239157 |
| 96 | CAMK4 | 0.28180942 |
| 97 | PRKAA2 | 0.28068306 |
| 98 | PRKD2 | 0.28001777 |
| 99 | ADRBK2 | 0.27406031 |
| 100 | OXSR1 | 0.26675471 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Leishmaniasis_Homo sapiens_hsa05140 | 3.30225338 |
| 2 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.78464276 |
| 3 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.65534274 |
| 4 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 2.61742806 |
| 5 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.52289880 |
| 6 | Allograft rejection_Homo sapiens_hsa05330 | 2.48880239 |
| 7 | Phagosome_Homo sapiens_hsa04145 | 2.48699632 |
| 8 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.38188227 |
| 9 | Tuberculosis_Homo sapiens_hsa05152 | 2.29499631 |
| 10 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.16561580 |
| 11 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.14782739 |
| 12 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 2.07703597 |
| 13 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.04115815 |
| 14 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.88065398 |
| 15 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.86626317 |
| 16 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.84740775 |
| 17 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.84144223 |
| 18 | Measles_Homo sapiens_hsa05162 | 1.78279201 |
| 19 | Apoptosis_Homo sapiens_hsa04210 | 1.73504845 |
| 20 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.65576786 |
| 21 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.55493629 |
| 22 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.52878638 |
| 23 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.50637862 |
| 24 | Asthma_Homo sapiens_hsa05310 | 1.45158716 |
| 25 | Influenza A_Homo sapiens_hsa05164 | 1.45138376 |
| 26 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.41748901 |
| 27 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.40759900 |
| 28 | Legionellosis_Homo sapiens_hsa05134 | 1.40194984 |
| 29 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.39975931 |
| 30 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.39075586 |
| 31 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.38991948 |
| 32 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.38198918 |
| 33 | Malaria_Homo sapiens_hsa05144 | 1.36917103 |
| 34 | Gap junction_Homo sapiens_hsa04540 | 1.36805407 |
| 35 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.35332114 |
| 36 | Viral myocarditis_Homo sapiens_hsa05416 | 1.28264005 |
| 37 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.27090738 |
| 38 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.21094856 |
| 39 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.18428238 |
| 40 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.13317892 |
| 41 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.12247641 |
| 42 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.09170419 |
| 43 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.08087773 |
| 44 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.05232172 |
| 45 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.03279072 |
| 46 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.00278413 |
| 47 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.97854841 |
| 48 | Hepatitis B_Homo sapiens_hsa05161 | 0.97663402 |
| 49 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.96459225 |
| 50 | Platelet activation_Homo sapiens_hsa04611 | 0.96331502 |
| 51 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.84593672 |
| 52 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.84513625 |
| 53 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.83819220 |
| 54 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.83442990 |
| 55 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.82547074 |
| 56 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.80283413 |
| 57 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.80173451 |
| 58 | Olfactory transduction_Homo sapiens_hsa04740 | 0.77182855 |
| 59 | Hepatitis C_Homo sapiens_hsa05160 | 0.75515477 |
| 60 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.70139584 |
| 61 | Shigellosis_Homo sapiens_hsa05131 | 0.67585833 |
| 62 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.65940298 |
| 63 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.65330131 |
| 64 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.65085088 |
| 65 | Endometrial cancer_Homo sapiens_hsa05213 | 0.64777579 |
| 66 | Endocytosis_Homo sapiens_hsa04144 | 0.63437676 |
| 67 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.62110301 |
| 68 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.59991399 |
| 69 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.59383998 |
| 70 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.57274451 |
| 71 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.57238629 |
| 72 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.56162203 |
| 73 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.54569758 |
| 74 | Pertussis_Homo sapiens_hsa05133 | 0.54471769 |
| 75 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.53234011 |
| 76 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.50764479 |
| 77 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.48914208 |
| 78 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.44433420 |
| 79 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.43855329 |
| 80 | Salmonella infection_Homo sapiens_hsa05132 | 0.43575662 |
| 81 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.42462366 |
| 82 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.41439119 |
| 83 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.41118184 |
| 84 | Alcoholism_Homo sapiens_hsa05034 | 0.40489610 |
| 85 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.39087358 |
| 86 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.37783649 |
| 87 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.35187618 |
| 88 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.33986590 |
| 89 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.31332471 |
| 90 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.30437405 |
| 91 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.27823071 |
| 92 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.27393380 |
| 93 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.27339564 |
| 94 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.26466137 |
| 95 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.25922363 |
| 96 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.23215681 |
| 97 | Lysosome_Homo sapiens_hsa04142 | 0.23076039 |
| 98 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.22884004 |
| 99 | Circadian rhythm_Homo sapiens_hsa04710 | 0.22719280 |
| 100 | ABC transporters_Homo sapiens_hsa02010 | 0.22718757 |

