

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | thrombin receptor signaling pathway (GO:0070493) | 8.50437768 |
| 2 | protein neddylation (GO:0045116) | 7.40217651 |
| 3 | neutrophil activation involved in immune response (GO:0002283) | 7.09178685 |
| 4 | regulation of platelet aggregation (GO:0090330) | 6.11649600 |
| 5 | regulation of platelet activation (GO:0010543) | 5.90020132 |
| 6 | blood coagulation, intrinsic pathway (GO:0007597) | 5.71693265 |
| 7 | platelet aggregation (GO:0070527) | 5.42833074 |
| 8 | leukocyte migration involved in inflammatory response (GO:0002523) | 5.12325420 |
| 9 | positive regulation of mast cell activation (GO:0033005) | 4.81764607 |
| 10 | adenosine receptor signaling pathway (GO:0001973) | 4.75718126 |
| 11 | angiogenesis involved in wound healing (GO:0060055) | 4.68757885 |
| 12 | positive regulation of endothelial cell differentiation (GO:0045603) | 4.68396663 |
| 13 | negative regulation of thymocyte apoptotic process (GO:0070244) | 4.62592062 |
| 14 | negative regulation of platelet activation (GO:0010544) | 4.62551685 |
| 15 | regulation of integrin-mediated signaling pathway (GO:2001044) | 4.61965393 |
| 16 | negative regulation of homotypic cell-cell adhesion (GO:0034111) | 4.61715925 |
| 17 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 4.58991887 |
| 18 | lipoxygenase pathway (GO:0019372) | 4.57775149 |
| 19 | purinergic nucleotide receptor signaling pathway (GO:0035590) | 4.55297983 |
| 20 | negative regulation of norepinephrine secretion (GO:0010700) | 4.52199605 |
| 21 | negative regulation of macrophage derived foam cell differentiation (GO:0010745) | 4.45813477 |
| 22 | neutrophil activation (GO:0042119) | 4.42968583 |
| 23 | regulation of integrin activation (GO:0033623) | 4.39641612 |
| 24 | negative regulation of heart rate (GO:0010459) | 4.39586799 |
| 25 | megakaryocyte development (GO:0035855) | 4.29962007 |
| 26 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 4.29747419 |
| 27 | positive regulation of cAMP-mediated signaling (GO:0043950) | 4.02590770 |
| 28 | regulation of lipoprotein metabolic process (GO:0050746) | 3.95073389 |
| 29 | fusion of sperm to egg plasma membrane (GO:0007342) | 3.86673852 |
| 30 | polyamine biosynthetic process (GO:0006596) | 3.83693790 |
| 31 | granulocyte activation (GO:0036230) | 3.81513267 |
| 32 | platelet degranulation (GO:0002576) | 3.76845067 |
| 33 | homotypic cell-cell adhesion (GO:0034109) | 3.76760775 |
| 34 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 3.75267718 |
| 35 | platelet formation (GO:0030220) | 3.70306023 |
| 36 | regulation of MHC class II biosynthetic process (GO:0045346) | 3.67809306 |
| 37 | negative regulation of response to food (GO:0032096) | 3.65524045 |
| 38 | negative regulation of appetite (GO:0032099) | 3.65524045 |
| 39 | purinergic receptor signaling pathway (GO:0035587) | 3.65450934 |
| 40 | low-density lipoprotein particle remodeling (GO:0034374) | 3.62635423 |
| 41 | regulation of Golgi to plasma membrane protein transport (GO:0042996) | 3.60548620 |
| 42 | positive regulation of macrophage differentiation (GO:0045651) | 3.54436036 |
| 43 | platelet activation (GO:0030168) | 3.53447132 |
| 44 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.52749988 |
| 45 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.52749988 |
| 46 | regulation of homotypic cell-cell adhesion (GO:0034110) | 3.51210042 |
| 47 | regulation of memory T cell differentiation (GO:0043380) | 3.49608390 |
| 48 | autophagic vacuole fusion (GO:0000046) | 3.46011652 |
| 49 | regulation of mast cell activation (GO:0033003) | 3.42160090 |
| 50 | positive regulation of blood coagulation (GO:0030194) | 3.41189404 |
| 51 | positive regulation of hemostasis (GO:1900048) | 3.41189404 |
| 52 | regulation of macrophage derived foam cell differentiation (GO:0010743) | 3.39317429 |
| 53 | positive regulation of granulocyte differentiation (GO:0030854) | 3.34937724 |
| 54 | negative regulation of protein localization to cell surface (GO:2000009) | 3.33847678 |
| 55 | regulation of endothelial cell differentiation (GO:0045601) | 3.30507064 |
| 56 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.27133455 |
| 57 | regulation of female receptivity (GO:0045924) | 3.24292950 |
| 58 | negative regulation of T cell apoptotic process (GO:0070233) | 3.21895997 |
| 59 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 3.19112201 |
| 60 | positive regulation of mast cell degranulation (GO:0043306) | 3.19112201 |
| 61 | leukocyte degranulation (GO:0043299) | 3.18038092 |
| 62 | termination of G-protein coupled receptor signaling pathway (GO:0038032) | 3.17400035 |
| 63 | positive regulation of systemic arterial blood pressure (GO:0003084) | 3.16897482 |
| 64 | positive regulation of Rho protein signal transduction (GO:0035025) | 3.13911366 |
| 65 | regulation of mast cell degranulation (GO:0043304) | 3.13624218 |
| 66 | negative regulation of neural precursor cell proliferation (GO:2000178) | 3.13350018 |
| 67 | regulation of norepinephrine secretion (GO:0014061) | 3.09819070 |
| 68 | monoamine transport (GO:0015844) | 3.08693018 |
| 69 | regulation of mast cell activation involved in immune response (GO:0033006) | 3.07998071 |
| 70 | mitochondrial calcium ion transport (GO:0006851) | 3.06101873 |
| 71 | G-protein coupled purinergic receptor signaling pathway (GO:0035588) | 3.04558307 |
| 72 | positive regulation of coagulation (GO:0050820) | 3.03975332 |
| 73 | negative regulation of heart contraction (GO:0045822) | 3.03972700 |
| 74 | termination of signal transduction (GO:0023021) | 3.03808899 |
| 75 | cellular biogenic amine biosynthetic process (GO:0042401) | 3.03691427 |
| 76 | positive regulation of mitochondrial calcium ion concentration (GO:0051561) | 3.03140939 |
| 77 | cyclooxygenase pathway (GO:0019371) | 3.01526423 |
| 78 | pyrimidine nucleoside catabolic process (GO:0046135) | 2.99081763 |
| 79 | endothelium development (GO:0003158) | 2.98720845 |
| 80 | regulation of regulatory T cell differentiation (GO:0045589) | 2.97498991 |
| 81 | long-chain fatty acid biosynthetic process (GO:0042759) | 2.97217753 |
| 82 | fatty acid elongation (GO:0030497) | 2.95630067 |
| 83 | phagocytosis, engulfment (GO:0006911) | 2.94900504 |
| 84 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 2.94157789 |
| 85 | regulation of megakaryocyte differentiation (GO:0045652) | 2.87946942 |
| 86 | amine biosynthetic process (GO:0009309) | 2.87559954 |
| 87 | plasma membrane fusion (GO:0045026) | 2.83943506 |
| 88 | regulation of hemostasis (GO:1900046) | 2.83427461 |
| 89 | regulation of blood coagulation (GO:0030193) | 2.83427461 |
| 90 | dopamine transport (GO:0015872) | 2.82250460 |
| 91 | regulation of T-helper 1 cell differentiation (GO:0045625) | 2.82018168 |
| 92 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.81843550 |
| 93 | regulation of inositol phosphate biosynthetic process (GO:0010919) | 2.79742759 |
| 94 | negative regulation of catecholamine secretion (GO:0033604) | 2.79114713 |
| 95 | beta-amyloid metabolic process (GO:0050435) | 2.77420491 |
| 96 | relaxation of smooth muscle (GO:0044557) | 2.76481680 |
| 97 | superoxide anion generation (GO:0042554) | 2.76171623 |
| 98 | female mating behavior (GO:0060180) | 2.75389522 |
| 99 | regulation of mitochondrial depolarization (GO:0051900) | 2.74934951 |
| 100 | organelle membrane fusion (GO:0090174) | 2.72995204 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 4.61570599 |
| 2 | SCL_19346495_ChIP-Seq_HPC-7_Human | 4.60398415 |
| 3 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 4.35281471 |
| 4 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.26224065 |
| 5 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 3.16990482 |
| 6 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 3.14411282 |
| 7 | GATA1_19941826_ChIP-Seq_K562_Human | 2.97172242 |
| 8 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 2.89084824 |
| 9 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.64011857 |
| 10 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.61783255 |
| 11 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.53321753 |
| 12 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 2.42679851 |
| 13 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.42671502 |
| 14 | GATA2_19941826_ChIP-Seq_K562_Human | 2.42550662 |
| 15 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 2.25701330 |
| 16 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.24182104 |
| 17 | SPI1_23127762_ChIP-Seq_K562_Human | 2.20766278 |
| 18 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.17430460 |
| 19 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.13668673 |
| 20 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.12085646 |
| 21 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.11569810 |
| 22 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 2.02704443 |
| 23 | GATA1_22025678_ChIP-Seq_K562_Human | 2.02508576 |
| 24 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.96296714 |
| 25 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.95904126 |
| 26 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.94596996 |
| 27 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.91655946 |
| 28 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.87142986 |
| 29 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.86615533 |
| 30 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.85518745 |
| 31 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.83134572 |
| 32 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 1.72822227 |
| 33 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.68504089 |
| 34 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.68012469 |
| 35 | VDR_22108803_ChIP-Seq_LS180_Human | 1.61740685 |
| 36 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.57419495 |
| 37 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.56554236 |
| 38 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.48223928 |
| 39 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.46367218 |
| 40 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.44319134 |
| 41 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.43546868 |
| 42 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 1.42416785 |
| 43 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.42358296 |
| 44 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.37699276 |
| 45 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.37621568 |
| 46 | KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse | 1.33262224 |
| 47 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.32320389 |
| 48 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.29864262 |
| 49 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.21844917 |
| 50 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.21742364 |
| 51 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.20920685 |
| 52 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 1.17186512 |
| 53 | EWS_26573619_Chip-Seq_HEK293_Human | 1.15930242 |
| 54 | GATA3_26560356_Chip-Seq_TH2_Human | 1.15117578 |
| 55 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.14009718 |
| 56 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.13994375 |
| 57 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.13266036 |
| 58 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.12746953 |
| 59 | ETS1_22383799_ChIP-Seq_G1ME_Mouse | 1.11586904 |
| 60 | SPI1_20517297_ChIP-Seq_HL60_Human | 1.09254156 |
| 61 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.07371677 |
| 62 | MYB_26560356_Chip-Seq_TH2_Human | 1.07116685 |
| 63 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.06788840 |
| 64 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.05391650 |
| 65 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.03852919 |
| 66 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.01098221 |
| 67 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.00756579 |
| 68 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.00703360 |
| 69 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.00703360 |
| 70 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.00127599 |
| 71 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.99790684 |
| 72 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.97355965 |
| 73 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.96991032 |
| 74 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.96033032 |
| 75 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.96033032 |
| 76 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.94528816 |
| 77 | AR_20517297_ChIP-Seq_VCAP_Human | 0.93273512 |
| 78 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.93138836 |
| 79 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.92685907 |
| 80 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.91897956 |
| 81 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 0.91809218 |
| 82 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.89369303 |
| 83 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.89103153 |
| 84 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.87229730 |
| 85 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.87229730 |
| 86 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.86638606 |
| 87 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.86003750 |
| 88 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.84859395 |
| 89 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.84587171 |
| 90 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.84285477 |
| 91 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.83494471 |
| 92 | AR_25329375_ChIP-Seq_VCAP_Human | 0.82859570 |
| 93 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.82243666 |
| 94 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.81497854 |
| 95 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.81480026 |
| 96 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.81404862 |
| 97 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.80486992 |
| 98 | UTX_26944678_Chip-Seq_JUKART_Human | 0.79755331 |
| 99 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.79646941 |
| 100 | LMO2_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.79396100 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005464_abnormal_platelet_physiology | 9.31946467 |
| 2 | MP0008004_abnormal_stomach_pH | 5.08257794 |
| 3 | MP0003724_increased_susceptibility_to | 4.02920294 |
| 4 | MP0000465_gastrointestinal_hemorrhage | 3.97038166 |
| 5 | MP0001835_abnormal_antigen_presentation | 2.58546770 |
| 6 | MP0004510_myositis | 2.53588321 |
| 7 | MP0003303_peritoneal_inflammation | 2.41623460 |
| 8 | MP0002736_abnormal_nociception_after | 2.30214859 |
| 9 | MP0005083_abnormal_biliary_tract | 2.24259986 |
| 10 | MP0000230_abnormal_systemic_arterial | 2.14663286 |
| 11 | MP0000343_altered_response_to | 2.03664805 |
| 12 | MP0004084_abnormal_cardiac_muscle | 2.01097330 |
| 13 | MP0008775_abnormal_heart_ventricle | 1.92606434 |
| 14 | MP0005084_abnormal_gallbladder_morpholo | 1.92595392 |
| 15 | MP0005410_abnormal_fertilization | 1.91998960 |
| 16 | MP0005646_abnormal_pituitary_gland | 1.91608596 |
| 17 | MP0005167_abnormal_blood-brain_barrier | 1.89520952 |
| 18 | MP0002148_abnormal_hypersensitivity_rea | 1.86918161 |
| 19 | MP0008872_abnormal_physiological_respon | 1.86091896 |
| 20 | MP0005671_abnormal_response_to | 1.76713431 |
| 21 | MP0001968_abnormal_touch/_nociception | 1.75788880 |
| 22 | MP0005000_abnormal_immune_tolerance | 1.65252471 |
| 23 | MP0003638_abnormal_response/metabolism_ | 1.64233495 |
| 24 | MP0001545_abnormal_hematopoietic_system | 1.57920609 |
| 25 | MP0005397_hematopoietic_system_phenotyp | 1.57920609 |
| 26 | MP0010155_abnormal_intestine_physiology | 1.57021446 |
| 27 | MP0002398_abnormal_bone_marrow | 1.53156161 |
| 28 | MP0003436_decreased_susceptibility_to | 1.52691110 |
| 29 | MP0002132_abnormal_respiratory_system | 1.47561743 |
| 30 | MP0003828_pulmonary_edema | 1.47362549 |
| 31 | MP0002733_abnormal_thermal_nociception | 1.46050275 |
| 32 | MP0001851_eye_inflammation | 1.44273996 |
| 33 | MP0003566_abnormal_cell_adhesion | 1.41464178 |
| 34 | MP0001663_abnormal_digestive_system | 1.37808070 |
| 35 | MP0001800_abnormal_humoral_immune | 1.36655037 |
| 36 | MP0004130_abnormal_muscle_cell | 1.35720504 |
| 37 | MP0002723_abnormal_immune_serum | 1.35132199 |
| 38 | MP0004036_abnormal_muscle_relaxation | 1.34650431 |
| 39 | MP0009764_decreased_sensitivity_to | 1.27035687 |
| 40 | MP0003879_abnormal_hair_cell | 1.26368615 |
| 41 | MP0002452_abnormal_antigen_presenting | 1.24752439 |
| 42 | MP0001879_abnormal_lymphatic_vessel | 1.21604693 |
| 43 | MP0001533_abnormal_skeleton_physiology | 1.20814207 |
| 44 | MP0000249_abnormal_blood_vessel | 1.20454241 |
| 45 | MP0000689_abnormal_spleen_morphology | 1.20366529 |
| 46 | MP0009763_increased_sensitivity_to | 1.17354608 |
| 47 | MP0006276_abnormal_autonomic_nervous | 1.15192489 |
| 48 | MP0004947_skin_inflammation | 1.15042759 |
| 49 | MP0003866_abnormal_defecation | 1.13077815 |
| 50 | MP0002420_abnormal_adaptive_immunity | 1.12475409 |
| 51 | MP0001819_abnormal_immune_cell | 1.10936185 |
| 52 | MP0002429_abnormal_blood_cell | 1.10503946 |
| 53 | MP0010329_abnormal_lipoprotein_level | 1.04881531 |
| 54 | MP0000015_abnormal_ear_pigmentation | 1.03666835 |
| 55 | MP0001970_abnormal_pain_threshold | 1.02333348 |
| 56 | MP0002419_abnormal_innate_immunity | 1.01862616 |
| 57 | MP0002722_abnormal_immune_system | 1.01053816 |
| 58 | MP0005387_immune_system_phenotype | 1.00646975 |
| 59 | MP0001790_abnormal_immune_system | 1.00646975 |
| 60 | MP0009765_abnormal_xenobiotic_induced | 0.98631430 |
| 61 | MP0005025_abnormal_response_to | 0.97790705 |
| 62 | MP0003656_abnormal_erythrocyte_physiolo | 0.97667012 |
| 63 | MP0005058_abnormal_lysosome_morphology | 0.97595659 |
| 64 | MP0000716_abnormal_immune_system | 0.97198579 |
| 65 | MP0004215_abnormal_myocardial_fiber | 0.95849730 |
| 66 | MP0001765_abnormal_ion_homeostasis | 0.95563180 |
| 67 | MP0003718_maternal_effect | 0.95239903 |
| 68 | MP0005174_abnormal_tail_pigmentation | 0.94571161 |
| 69 | MP0001845_abnormal_inflammatory_respons | 0.93579168 |
| 70 | MP0000685_abnormal_immune_system | 0.93215065 |
| 71 | MP0009642_abnormal_blood_homeostasis | 0.93196734 |
| 72 | MP0005535_abnormal_body_temperature | 0.91094108 |
| 73 | MP0004142_abnormal_muscle_tone | 0.90485944 |
| 74 | MP0002735_abnormal_chemical_nociception | 0.88408577 |
| 75 | MP0006054_spinal_hemorrhage | 0.87925565 |
| 76 | MP0008874_decreased_physiological_sensi | 0.87828281 |
| 77 | MP0009333_abnormal_splenocyte_physiolog | 0.87823737 |
| 78 | MP0009697_abnormal_copulation | 0.86137788 |
| 79 | MP0006036_abnormal_mitochondrial_physio | 0.85779559 |
| 80 | MP0004484_altered_response_of | 0.85456724 |
| 81 | MP0001664_abnormal_digestion | 0.84742311 |
| 82 | MP0005381_digestive/alimentary_phenotyp | 0.80660892 |
| 83 | MP0002653_abnormal_ependyma_morphology | 0.79929091 |
| 84 | MP0005165_increased_susceptibility_to | 0.76946776 |
| 85 | MP0003300_gastrointestinal_ulcer | 0.76122060 |
| 86 | MP0004808_abnormal_hematopoietic_stem | 0.74844343 |
| 87 | MP0003011_delayed_dark_adaptation | 0.67050676 |
| 88 | MP0009785_altered_susceptibility_to | 0.65592451 |
| 89 | MP0001756_abnormal_urination | 0.64523418 |
| 90 | MP0000858_altered_metastatic_potential | 0.63377818 |
| 91 | MP0004147_increased_porphyrin_level | 0.63271430 |
| 92 | MP0000703_abnormal_thymus_morphology | 0.62179169 |
| 93 | MP0002118_abnormal_lipid_homeostasis | 0.61938411 |
| 94 | MP0001544_abnormal_cardiovascular_syste | 0.61734685 |
| 95 | MP0005385_cardiovascular_system_phenoty | 0.61734685 |
| 96 | MP0004085_abnormal_heartbeat | 0.60159130 |
| 97 | MP0002405_respiratory_system_inflammati | 0.59916158 |
| 98 | MP0006035_abnormal_mitochondrial_morpho | 0.58715867 |
| 99 | MP0003186_abnormal_redox_activity | 0.58514055 |
| 100 | MP0002998_abnormal_bone_remodeling | 0.57881523 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormal platelet volume (HP:0011876) | 9.83545586 |
| 2 | Purpura (HP:0000979) | 8.84532805 |
| 3 | Epistaxis (HP:0000421) | 7.60851151 |
| 4 | Gingival bleeding (HP:0000225) | 6.79218778 |
| 5 | Impaired platelet aggregation (HP:0003540) | 5.59095711 |
| 6 | Abnormal platelet function (HP:0011869) | 5.59095711 |
| 7 | Hyperlipoproteinemia (HP:0010980) | 5.10706757 |
| 8 | Poikilocytosis (HP:0004447) | 4.15380951 |
| 9 | Spontaneous hematomas (HP:0007420) | 4.10601448 |
| 10 | Acanthocytosis (HP:0001927) | 3.94994365 |
| 11 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 3.65878777 |
| 12 | Dyschromatopsia (HP:0007641) | 3.64280030 |
| 13 | Bruising susceptibility (HP:0000978) | 3.35137971 |
| 14 | Abnormal pupillary function (HP:0007686) | 3.31040765 |
| 15 | Stomatitis (HP:0010280) | 3.22061752 |
| 16 | Conjunctival telangiectasia (HP:0000524) | 3.08002936 |
| 17 | Abnormality of the common coagulation pathway (HP:0010990) | 2.97241007 |
| 18 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 2.85957300 |
| 19 | Paralysis (HP:0003470) | 2.82269480 |
| 20 | Decreased central vision (HP:0007663) | 2.80810479 |
| 21 | Increased density of long bones (HP:0006392) | 2.67974630 |
| 22 | Abnormality of lateral ventricle (HP:0030047) | 2.60991827 |
| 23 | Tinnitus (HP:0000360) | 2.38937625 |
| 24 | Abnormality of iron homeostasis (HP:0011031) | 2.34066199 |
| 25 | Hepatosplenomegaly (HP:0001433) | 2.32348225 |
| 26 | Increased IgM level (HP:0003496) | 2.31461179 |
| 27 | Joint swelling (HP:0001386) | 2.31264448 |
| 28 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.22475247 |
| 29 | Abnormality of transition element cation homeostasis (HP:0011030) | 2.22407563 |
| 30 | Hyperthyroidism (HP:0000836) | 2.19848205 |
| 31 | Joint hemorrhage (HP:0005261) | 2.17484631 |
| 32 | Obstructive lung disease (HP:0006536) | 2.17306954 |
| 33 | Chronic obstructive pulmonary disease (HP:0006510) | 2.17306954 |
| 34 | Encephalitis (HP:0002383) | 2.15265754 |
| 35 | Spontaneous abortion (HP:0005268) | 2.14482036 |
| 36 | Generalized aminoaciduria (HP:0002909) | 2.11833407 |
| 37 | Abnormal auditory evoked potentials (HP:0006958) | 2.11516339 |
| 38 | Abnormality of macrophages (HP:0004311) | 2.09262680 |
| 39 | Arterial thrombosis (HP:0004420) | 2.07507518 |
| 40 | Thyroid-stimulating hormone excess (HP:0002925) | 2.04654999 |
| 41 | Episodic fever (HP:0001954) | 2.00148642 |
| 42 | Prolonged bleeding time (HP:0003010) | 11.6931790 |
| 43 | Increased mean platelet volume (HP:0011877) | 10.3977582 |
| 44 | Menorrhagia (HP:0000132) | 10.2791398 |
| 45 | Petechiae (HP:0000967) | 10.1314770 |
| 46 | 3-Methylglutaconic aciduria (HP:0003535) | 1.99224097 |
| 47 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.93896926 |
| 48 | Absent/shortened dynein arms (HP:0200106) | 1.93896926 |
| 49 | Autoimmune hemolytic anemia (HP:0001890) | 1.93145899 |
| 50 | Nausea (HP:0002018) | 1.92792478 |
| 51 | Abnormal ciliary motility (HP:0012262) | 1.91261614 |
| 52 | Abnormality of the prostate (HP:0008775) | 1.88748226 |
| 53 | Chronic otitis media (HP:0000389) | 1.85293343 |
| 54 | Xanthomatosis (HP:0000991) | 1.83585705 |
| 55 | Increased serum ferritin (HP:0003281) | 1.83560013 |
| 56 | Upper limb muscle weakness (HP:0003484) | 1.80300349 |
| 57 | Vertigo (HP:0002321) | 1.80076515 |
| 58 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.77058904 |
| 59 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.77058904 |
| 60 | Chest pain (HP:0100749) | 1.75298584 |
| 61 | Male infertility (HP:0003251) | 1.73719982 |
| 62 | Ventricular fibrillation (HP:0001663) | 1.70764599 |
| 63 | Tongue fasciculations (HP:0001308) | 1.66567652 |
| 64 | Panhypogammaglobulinemia (HP:0003139) | 1.65176180 |
| 65 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.63218568 |
| 66 | Abnormality of alanine metabolism (HP:0010916) | 1.63218568 |
| 67 | Hyperalaninemia (HP:0003348) | 1.63218568 |
| 68 | Thrombocytosis (HP:0001894) | 1.61987536 |
| 69 | Polyphagia (HP:0002591) | 1.60219804 |
| 70 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 1.59419464 |
| 71 | Leukocytosis (HP:0001974) | 1.56185677 |
| 72 | Hypophosphatemic rickets (HP:0004912) | 1.55677553 |
| 73 | Muscle fibrillation (HP:0010546) | 1.55288081 |
| 74 | Dysautonomia (HP:0002459) | 1.54760054 |
| 75 | Renal Fanconi syndrome (HP:0001994) | 1.54434044 |
| 76 | Basal ganglia calcification (HP:0002135) | 1.52766708 |
| 77 | Papillary thyroid carcinoma (HP:0002895) | 1.52590709 |
| 78 | Diplopia (HP:0000651) | 1.52506596 |
| 79 | Abnormality of binocular vision (HP:0011514) | 1.52506596 |
| 80 | Central scotoma (HP:0000603) | 1.51535907 |
| 81 | Exertional dyspnea (HP:0002875) | 1.51303639 |
| 82 | Polycythemia (HP:0001901) | 1.50176811 |
| 83 | Abolished electroretinogram (ERG) (HP:0000550) | 1.44904429 |
| 84 | Amaurosis fugax (HP:0100576) | 1.44157764 |
| 85 | Visual hallucinations (HP:0002367) | 1.40452677 |
| 86 | Thrombophlebitis (HP:0004418) | 1.39868211 |
| 87 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 1.38612364 |
| 88 | Arthropathy (HP:0003040) | 1.38279268 |
| 89 | Eczematoid dermatitis (HP:0000976) | 1.36090132 |
| 90 | Renal cortical cysts (HP:0000803) | 1.35743796 |
| 91 | Granulocytopenia (HP:0001913) | 1.35197790 |
| 92 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 1.34175000 |
| 93 | Hypomagnesemia (HP:0002917) | 1.33680096 |
| 94 | Recurrent abscess formation (HP:0002722) | 1.33046577 |
| 95 | Inflammation of the large intestine (HP:0002037) | 1.32661285 |
| 96 | Biliary tract neoplasm (HP:0100574) | 1.32621585 |
| 97 | Thyroid carcinoma (HP:0002890) | 1.31712713 |
| 98 | Clumsiness (HP:0002312) | 1.31499071 |
| 99 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 1.31283001 |
| 100 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 1.29420461 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK4 | 4.94176738 |
| 2 | MST4 | 4.41279527 |
| 3 | BMX | 3.62795590 |
| 4 | TEC | 3.44061867 |
| 5 | TAOK3 | 3.43474170 |
| 6 | MYLK | 3.09015231 |
| 7 | BTK | 2.95367625 |
| 8 | EIF2AK1 | 2.59838710 |
| 9 | SYK | 2.49950228 |
| 10 | PTK2B | 2.43166195 |
| 11 | PIK3CG | 2.15195291 |
| 12 | CSF1R | 2.06163468 |
| 13 | ADRBK2 | 2.04915347 |
| 14 | GRK5 | 1.92257030 |
| 15 | GRK6 | 1.86384089 |
| 16 | ZAP70 | 1.83413482 |
| 17 | BMPR2 | 1.66928175 |
| 18 | FES | 1.61978771 |
| 19 | TXK | 1.57052563 |
| 20 | NUAK1 | 1.53520735 |
| 21 | HCK | 1.52490259 |
| 22 | ILK | 1.52341046 |
| 23 | STK3 | 1.48705079 |
| 24 | TNK2 | 1.41000136 |
| 25 | MAPKAPK3 | 1.36406501 |
| 26 | IKBKB | 1.35994218 |
| 27 | ACVR1B | 1.34168224 |
| 28 | FGR | 1.30797316 |
| 29 | ITK | 1.23058534 |
| 30 | LYN | 1.22269993 |
| 31 | MAP2K3 | 1.19544591 |
| 32 | FRK | 1.14987253 |
| 33 | IRAK1 | 1.13202417 |
| 34 | MATK | 1.06432918 |
| 35 | DAPK2 | 1.05852274 |
| 36 | TLK1 | 1.05339921 |
| 37 | MAP4K2 | 1.04045924 |
| 38 | PNCK | 1.03955321 |
| 39 | BMPR1B | 1.03199314 |
| 40 | PLK2 | 1.01438555 |
| 41 | ADRBK1 | 1.01277346 |
| 42 | BLK | 1.00740895 |
| 43 | TNIK | 0.96980388 |
| 44 | PIM2 | 0.94967748 |
| 45 | PAK1 | 0.93387026 |
| 46 | DAPK3 | 0.90292766 |
| 47 | MAP3K5 | 0.86992750 |
| 48 | EPHA3 | 0.85975156 |
| 49 | SIK3 | 0.79603318 |
| 50 | MAP4K1 | 0.79403473 |
| 51 | MARK3 | 0.78987883 |
| 52 | PDK1 | 0.76729945 |
| 53 | TRIM28 | 0.73196547 |
| 54 | PKN1 | 0.72161862 |
| 55 | LMTK2 | 0.71622354 |
| 56 | MAPK13 | 0.71285172 |
| 57 | ZAK | 0.71255182 |
| 58 | FER | 0.69391458 |
| 59 | GRK1 | 0.68230216 |
| 60 | JAK3 | 0.66445680 |
| 61 | LCK | 0.64865081 |
| 62 | ERBB2 | 0.64544320 |
| 63 | CSK | 0.61679434 |
| 64 | CAMKK2 | 0.60850261 |
| 65 | PDPK1 | 0.57876575 |
| 66 | PRKD1 | 0.55493846 |
| 67 | PRKACG | 0.54910520 |
| 68 | PRKCQ | 0.54478544 |
| 69 | MAP2K1 | 0.54025864 |
| 70 | STK24 | 0.51984864 |
| 71 | MAPK12 | 0.50299690 |
| 72 | TESK2 | 0.49765626 |
| 73 | DAPK1 | 0.49487774 |
| 74 | MAP3K11 | 0.48059866 |
| 75 | DYRK2 | 0.47359439 |
| 76 | TAOK2 | 0.45554905 |
| 77 | JAK2 | 0.43600511 |
| 78 | PRKG1 | 0.43463612 |
| 79 | PAK3 | 0.41804018 |
| 80 | BCKDK | 0.41773966 |
| 81 | RET | 0.41659129 |
| 82 | VRK1 | 0.40575275 |
| 83 | STK4 | 0.40521370 |
| 84 | PRKCD | 0.39697683 |
| 85 | IRAK4 | 0.37776147 |
| 86 | MINK1 | 0.37336077 |
| 87 | FYN | 0.36984295 |
| 88 | PRKCA | 0.36349305 |
| 89 | PIM1 | 0.34974986 |
| 90 | PRKCB | 0.32115508 |
| 91 | TAOK1 | 0.31173493 |
| 92 | KIT | 0.31012562 |
| 93 | CAMK1 | 0.30611381 |
| 94 | IGF1R | 0.29108080 |
| 95 | JAK1 | 0.26117379 |
| 96 | PRKCE | 0.25954893 |
| 97 | ABL1 | 0.24163670 |
| 98 | PRKACA | 0.24007044 |
| 99 | DYRK1A | 0.23202549 |
| 100 | YES1 | 0.22760117 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Platelet activation_Homo sapiens_hsa04611 | 5.67270605 |
| 2 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 3.15267009 |
| 3 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.89357167 |
| 4 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 2.78018058 |
| 5 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 2.72561061 |
| 6 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.60324200 |
| 7 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 2.45471212 |
| 8 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.99124155 |
| 9 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.81277366 |
| 10 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.75713262 |
| 11 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.75536542 |
| 12 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.74428289 |
| 13 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.61600660 |
| 14 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.48825130 |
| 15 | Gap junction_Homo sapiens_hsa04540 | 1.48561757 |
| 16 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.44666044 |
| 17 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.43622887 |
| 18 | Alcoholism_Homo sapiens_hsa05034 | 1.42293834 |
| 19 | Asthma_Homo sapiens_hsa05310 | 1.41470693 |
| 20 | Olfactory transduction_Homo sapiens_hsa04740 | 1.35784877 |
| 21 | Allograft rejection_Homo sapiens_hsa05330 | 1.27574679 |
| 22 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.26047989 |
| 23 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.25676777 |
| 24 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.24615294 |
| 25 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.19546055 |
| 26 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.15117444 |
| 27 | Long-term depression_Homo sapiens_hsa04730 | 1.12180589 |
| 28 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.11341448 |
| 29 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.10040647 |
| 30 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.09538574 |
| 31 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.06685773 |
| 32 | Phototransduction_Homo sapiens_hsa04744 | 1.05432023 |
| 33 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.04810510 |
| 34 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.01796000 |
| 35 | Circadian entrainment_Homo sapiens_hsa04713 | 1.00410723 |
| 36 | Malaria_Homo sapiens_hsa05144 | 0.99814028 |
| 37 | Endocytosis_Homo sapiens_hsa04144 | 0.99586973 |
| 38 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.99016093 |
| 39 | Shigellosis_Homo sapiens_hsa05131 | 0.98179706 |
| 40 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.97953605 |
| 41 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.97297765 |
| 42 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.97069967 |
| 43 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.96178946 |
| 44 | Morphine addiction_Homo sapiens_hsa05032 | 0.95232559 |
| 45 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.92611018 |
| 46 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.92292959 |
| 47 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.91043864 |
| 48 | Phagosome_Homo sapiens_hsa04145 | 0.84571823 |
| 49 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.83752109 |
| 50 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.81653872 |
| 51 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.80202942 |
| 52 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.78996338 |
| 53 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.78978805 |
| 54 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.78904363 |
| 55 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.78643650 |
| 56 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.77243296 |
| 57 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.76171490 |
| 58 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.75868089 |
| 59 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.73374036 |
| 60 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.72049924 |
| 61 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.71260395 |
| 62 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.68545391 |
| 63 | Leishmaniasis_Homo sapiens_hsa05140 | 0.66517668 |
| 64 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.62742332 |
| 65 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.62161589 |
| 66 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.62125147 |
| 67 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.60613641 |
| 68 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.59786424 |
| 69 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.59432463 |
| 70 | Renin secretion_Homo sapiens_hsa04924 | 0.59220288 |
| 71 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.59173263 |
| 72 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.57365874 |
| 73 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.56194327 |
| 74 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.55134620 |
| 75 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.55126958 |
| 76 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.54835497 |
| 77 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.52904199 |
| 78 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.51210402 |
| 79 | GABAergic synapse_Homo sapiens_hsa04727 | 0.50042020 |
| 80 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.49670535 |
| 81 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.49338779 |
| 82 | Legionellosis_Homo sapiens_hsa05134 | 0.48690440 |
| 83 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.47815227 |
| 84 | ABC transporters_Homo sapiens_hsa02010 | 0.45449029 |
| 85 | Salivary secretion_Homo sapiens_hsa04970 | 0.44970633 |
| 86 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.44659445 |
| 87 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.44437856 |
| 88 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.42655693 |
| 89 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.41650475 |
| 90 | Tuberculosis_Homo sapiens_hsa05152 | 0.40553687 |
| 91 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.40511973 |
| 92 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.38734225 |
| 93 | Mismatch repair_Homo sapiens_hsa03430 | 0.38684664 |
| 94 | Focal adhesion_Homo sapiens_hsa04510 | 0.38249861 |
| 95 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.38216605 |
| 96 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.36629345 |
| 97 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.36286981 |
| 98 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.34982323 |
| 99 | Viral myocarditis_Homo sapiens_hsa05416 | 0.34235863 |
| 100 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.33477065 |

