

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 6.03387537 |
| 2 | negative regulation of cell killing (GO:0031342) | 6.03387537 |
| 3 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.63116014 |
| 4 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 5.43142875 |
| 5 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.32958282 |
| 6 | antigen processing and presentation of endogenous antigen (GO:0019883) | 5.19346282 |
| 7 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.16982335 |
| 8 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.16982335 |
| 9 | modulation by symbiont of host immune response (GO:0052553) | 5.16982335 |
| 10 | positive regulation by symbiont of host defense response (GO:0052509) | 5.16982335 |
| 11 | modulation by symbiont of host defense response (GO:0052031) | 5.16982335 |
| 12 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.16982335 |
| 13 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.99063753 |
| 14 | detection of other organism (GO:0098543) | 4.66208023 |
| 15 | detection of bacterium (GO:0016045) | 4.57185838 |
| 16 | neutrophil activation involved in immune response (GO:0002283) | 4.52694485 |
| 17 | macrophage activation involved in immune response (GO:0002281) | 4.48650353 |
| 18 | leukocyte aggregation (GO:0070486) | 4.41549258 |
| 19 | response to peptidoglycan (GO:0032494) | 4.36872586 |
| 20 | negative regulation of erythrocyte differentiation (GO:0045647) | 4.29777556 |
| 21 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.06483322 |
| 22 | detection of external biotic stimulus (GO:0098581) | 3.97886153 |
| 23 | regulation of gamma-delta T cell activation (GO:0046643) | 3.94407877 |
| 24 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.82392512 |
| 25 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.81671917 |
| 26 | cellular extravasation (GO:0045123) | 3.74941942 |
| 27 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.73009136 |
| 28 | negative regulation of interleukin-12 production (GO:0032695) | 3.72656782 |
| 29 | detection of molecule of bacterial origin (GO:0032490) | 3.68269235 |
| 30 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.54478436 |
| 31 | response to interleukin-15 (GO:0070672) | 3.48263305 |
| 32 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.47890691 |
| 33 | respiratory burst (GO:0045730) | 3.46725699 |
| 34 | neutrophil activation (GO:0042119) | 3.45875165 |
| 35 | regulation of mast cell degranulation (GO:0043304) | 3.45325423 |
| 36 | immunoglobulin mediated immune response (GO:0016064) | 3.44484119 |
| 37 | detection of biotic stimulus (GO:0009595) | 3.43489903 |
| 38 | positive thymic T cell selection (GO:0045059) | 3.42610068 |
| 39 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.40188416 |
| 40 | response to host immune response (GO:0052572) | 3.40188416 |
| 41 | response to muramyl dipeptide (GO:0032495) | 3.39741786 |
| 42 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 3.38193046 |
| 43 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 3.33322251 |
| 44 | regulation of leukocyte degranulation (GO:0043300) | 3.32964612 |
| 45 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.32665983 |
| 46 | B cell receptor signaling pathway (GO:0050853) | 3.32457737 |
| 47 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 3.32418281 |
| 48 | granulocyte activation (GO:0036230) | 3.27368344 |
| 49 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.26700824 |
| 50 | germinal center formation (GO:0002467) | 3.25835250 |
| 51 | response to host (GO:0075136) | 3.25306660 |
| 52 | response to host defenses (GO:0052200) | 3.25306660 |
| 53 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.25306660 |
| 54 | cellular response to type I interferon (GO:0071357) | 3.23189910 |
| 55 | type I interferon signaling pathway (GO:0060337) | 3.23189910 |
| 56 | response to type I interferon (GO:0034340) | 3.22493323 |
| 57 | myeloid cell activation involved in immune response (GO:0002275) | 3.22040497 |
| 58 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.21028218 |
| 59 | negative thymic T cell selection (GO:0045060) | 3.17759367 |
| 60 | leukocyte migration involved in inflammatory response (GO:0002523) | 3.15797905 |
| 61 | negative regulation of T cell mediated immunity (GO:0002710) | 3.13753161 |
| 62 | regulation of T cell tolerance induction (GO:0002664) | 3.12749320 |
| 63 | thymic T cell selection (GO:0045061) | 3.11840335 |
| 64 | mannose metabolic process (GO:0006013) | 3.11163787 |
| 65 | macrophage activation (GO:0042116) | 3.08681250 |
| 66 | regulation of mast cell activation involved in immune response (GO:0033006) | 3.08026538 |
| 67 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.08001098 |
| 68 | T cell selection (GO:0045058) | 3.06021637 |
| 69 | negative T cell selection (GO:0043383) | 3.04112522 |
| 70 | NIK/NF-kappaB signaling (GO:0038061) | 3.04040542 |
| 71 | cellular response to interleukin-15 (GO:0071350) | 3.01659478 |
| 72 | production of molecular mediator involved in inflammatory response (GO:0002532) | 2.98693031 |
| 73 | negative regulation of phagocytosis (GO:0050765) | 2.98349670 |
| 74 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 2.97273987 |
| 75 | regulation of regulated secretory pathway (GO:1903305) | 2.93141818 |
| 76 | positive regulation of Cdc42 GTPase activity (GO:0043089) | 2.88054065 |
| 77 | tolerance induction (GO:0002507) | 2.87822761 |
| 78 | negative regulation of innate immune response (GO:0045824) | 2.87440155 |
| 79 | regulation of tolerance induction (GO:0002643) | 2.85788405 |
| 80 | positive T cell selection (GO:0043368) | 2.83801377 |
| 81 | microglial cell activation (GO:0001774) | 2.82830880 |
| 82 | defense response to protozoan (GO:0042832) | 2.82038471 |
| 83 | regulation of B cell differentiation (GO:0045577) | 2.81616461 |
| 84 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.81074922 |
| 85 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.80459768 |
| 86 | negative regulation of interleukin-6 production (GO:0032715) | 2.80053103 |
| 87 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 2.76668364 |
| 88 | positive regulation of B cell differentiation (GO:0045579) | 2.75600603 |
| 89 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 2.75143756 |
| 90 | negative regulation of type 2 immune response (GO:0002829) | 2.74969827 |
| 91 | negative regulation of toll-like receptor signaling pathway (GO:0034122) | 2.74365089 |
| 92 | positive regulation of mast cell activation (GO:0033005) | 2.71872201 |
| 93 | negative regulation of cytokine production involved in immune response (GO:0002719) | 2.70780378 |
| 94 | leukocyte degranulation (GO:0043299) | 2.70194099 |
| 95 | neutrophil mediated immunity (GO:0002446) | 2.69648000 |
| 96 | positive regulation of cellular amide metabolic process (GO:0034250) | 2.69505252 |
| 97 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 2.69199666 |
| 98 | regulation of natural killer cell mediated immunity (GO:0002715) | 2.69199666 |
| 99 | T cell migration (GO:0072678) | 2.67340415 |
| 100 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 2.66872525 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.54489106 |
| 2 | VDR_21846776_ChIP-Seq_THP-1_Human | 3.36361840 |
| 3 | MYC_22102868_ChIP-Seq_BL_Human | 2.94000655 |
| 4 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.82677559 |
| 5 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 2.60845352 |
| 6 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.60425229 |
| 7 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.53816870 |
| 8 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.49894692 |
| 9 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.47611056 |
| 10 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.47149901 |
| 11 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.45383938 |
| 12 | TCF7_22412390_ChIP-Seq_EML_Mouse | 2.44663102 |
| 13 | LXR_22292898_ChIP-Seq_THP-1_Human | 2.40264218 |
| 14 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.37149546 |
| 15 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 2.36676272 |
| 16 | * MAF_26560356_Chip-Seq_TH1_Human | 2.34067006 |
| 17 | KDM2B_26808549_Chip-Seq_DND41_Human | 2.28966522 |
| 18 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.28559079 |
| 19 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.28034007 |
| 20 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 2.24045770 |
| 21 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.21451498 |
| 22 | UTX_26944678_Chip-Seq_JUKART_Human | 2.11956199 |
| 23 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 2.11929495 |
| 24 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.09480375 |
| 25 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.08206857 |
| 26 | * SPI1_23127762_ChIP-Seq_K562_Human | 1.99882226 |
| 27 | MAF_26560356_Chip-Seq_TH2_Human | 1.99660126 |
| 28 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.99252576 |
| 29 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.97091850 |
| 30 | * SPI1_23547873_ChIP-Seq_NB4_Human | 1.97079895 |
| 31 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.96165342 |
| 32 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.95515489 |
| 33 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.91263354 |
| 34 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.89943332 |
| 35 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.88277420 |
| 36 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.88194124 |
| 37 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.86119214 |
| 38 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.75487824 |
| 39 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.74900927 |
| 40 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.69646083 |
| 41 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.68622816 |
| 42 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.67898582 |
| 43 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.66564639 |
| 44 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.65959457 |
| 45 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.63301149 |
| 46 | MYB_26560356_Chip-Seq_TH1_Human | 1.57451824 |
| 47 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.55823863 |
| 48 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.54808099 |
| 49 | MYB_26560356_Chip-Seq_TH2_Human | 1.54801712 |
| 50 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.53478365 |
| 51 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.49336986 |
| 52 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.47413665 |
| 53 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.47139201 |
| 54 | KDM2B_26808549_Chip-Seq_K562_Human | 1.42563854 |
| 55 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.40884824 |
| 56 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.40512466 |
| 57 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.38991556 |
| 58 | P68_20966046_ChIP-Seq_HELA_Human | 1.38119822 |
| 59 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.37423982 |
| 60 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.37335171 |
| 61 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.36006232 |
| 62 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.35601636 |
| 63 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.34500682 |
| 64 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.30633985 |
| 65 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.29724609 |
| 66 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.28308543 |
| 67 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.27753028 |
| 68 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.27127421 |
| 69 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.26433724 |
| 70 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.23891826 |
| 71 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.21470376 |
| 72 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.21457202 |
| 73 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.17873476 |
| 74 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.17190420 |
| 75 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.16719254 |
| 76 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.16268736 |
| 77 | GATA1_19941826_ChIP-Seq_K562_Human | 1.15934931 |
| 78 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.15085446 |
| 79 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.13633569 |
| 80 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.10034596 |
| 81 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.09967052 |
| 82 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.07569703 |
| 83 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.07369305 |
| 84 | * TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.07054777 |
| 85 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.06700986 |
| 86 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.05718128 |
| 87 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.04439052 |
| 88 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.04151732 |
| 89 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.03833545 |
| 90 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.03096647 |
| 91 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.01772397 |
| 92 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.01297501 |
| 93 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.00795712 |
| 94 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.00688107 |
| 95 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.00646741 |
| 96 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.00106202 |
| 97 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.98613028 |
| 98 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.97712212 |
| 99 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.97414948 |
| 100 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 0.94700398 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003436_decreased_susceptibility_to | 4.22482325 |
| 2 | MP0003724_increased_susceptibility_to | 3.84472890 |
| 3 | MP0003303_peritoneal_inflammation | 3.71044656 |
| 4 | MP0001835_abnormal_antigen_presentation | 3.08831224 |
| 5 | MP0002419_abnormal_innate_immunity | 2.80568572 |
| 6 | MP0005025_abnormal_response_to | 2.63773021 |
| 7 | MP0005000_abnormal_immune_tolerance | 2.63219468 |
| 8 | MP0005387_immune_system_phenotype | 2.62005628 |
| 9 | MP0001790_abnormal_immune_system | 2.62005628 |
| 10 | MP0001800_abnormal_humoral_immune | 2.60964779 |
| 11 | MP0000685_abnormal_immune_system | 2.58919870 |
| 12 | MP0003300_gastrointestinal_ulcer | 2.55759444 |
| 13 | MP0003172_abnormal_lysosome_physiology | 2.53022858 |
| 14 | MP0005671_abnormal_response_to | 2.45688386 |
| 15 | MP0008260_abnormal_autophagy | 2.45213795 |
| 16 | MP0003191_abnormal_cellular_cholesterol | 2.39802082 |
| 17 | MP0003763_abnormal_thymus_physiology | 2.38939666 |
| 18 | MP0009785_altered_susceptibility_to | 2.36146230 |
| 19 | MP0002723_abnormal_immune_serum | 2.35121709 |
| 20 | MP0006082_CNS_inflammation | 2.31291204 |
| 21 | MP0002420_abnormal_adaptive_immunity | 2.29986415 |
| 22 | MP0001819_abnormal_immune_cell | 2.27908598 |
| 23 | MP0002452_abnormal_antigen_presenting | 2.25592325 |
| 24 | MP0005058_abnormal_lysosome_morphology | 2.20225161 |
| 25 | MP0005451_abnormal_body_composition | 2.15632677 |
| 26 | MP0001533_abnormal_skeleton_physiology | 2.03090009 |
| 27 | MP0004947_skin_inflammation | 1.98164002 |
| 28 | MP0003705_abnormal_hypodermis_morpholog | 1.96752517 |
| 29 | MP0009333_abnormal_splenocyte_physiolog | 1.89718539 |
| 30 | MP0010155_abnormal_intestine_physiology | 1.89680655 |
| 31 | MP0009278_abnormal_bone_marrow | 1.88942596 |
| 32 | MP0002148_abnormal_hypersensitivity_rea | 1.88081959 |
| 33 | MP0002398_abnormal_bone_marrow | 1.84594467 |
| 34 | MP0005464_abnormal_platelet_physiology | 1.83817057 |
| 35 | MP0002405_respiratory_system_inflammati | 1.83801285 |
| 36 | MP0002132_abnormal_respiratory_system | 1.79469908 |
| 37 | MP0000716_abnormal_immune_system | 1.78513176 |
| 38 | MP0002396_abnormal_hematopoietic_system | 1.74672056 |
| 39 | MP0003183_abnormal_peptide_metabolism | 1.69985866 |
| 40 | MP0004381_abnormal_hair_follicle | 1.65554566 |
| 41 | MP0001845_abnormal_inflammatory_respons | 1.62323245 |
| 42 | MP0000858_altered_metastatic_potential | 1.59526486 |
| 43 | MP0003866_abnormal_defecation | 1.57572978 |
| 44 | MP0002722_abnormal_immune_system | 1.49745282 |
| 45 | MP0000703_abnormal_thymus_morphology | 1.48724674 |
| 46 | MP0004510_myositis | 1.48165784 |
| 47 | MP0009840_abnormal_foam_cell | 1.45821278 |
| 48 | MP0002429_abnormal_blood_cell | 1.44434037 |
| 49 | MP0000689_abnormal_spleen_morphology | 1.42676119 |
| 50 | MP0005310_abnormal_salivary_gland | 1.39857359 |
| 51 | MP0001873_stomach_inflammation | 1.36854363 |
| 52 | MP0008469_abnormal_protein_level | 1.34769637 |
| 53 | MP0003828_pulmonary_edema | 1.34562746 |
| 54 | MP0002998_abnormal_bone_remodeling | 1.31369145 |
| 55 | MP0005076_abnormal_cell_differentiation | 1.24807950 |
| 56 | MP0005397_hematopoietic_system_phenotyp | 1.24332903 |
| 57 | MP0001545_abnormal_hematopoietic_system | 1.24332903 |
| 58 | MP0003075_altered_response_to | 1.22676848 |
| 59 | MP0001851_eye_inflammation | 1.22383731 |
| 60 | MP0000465_gastrointestinal_hemorrhage | 1.17643862 |
| 61 | MP0003453_abnormal_keratinocyte_physiol | 1.17042143 |
| 62 | MP0004883_abnormal_blood_vessel | 1.10138706 |
| 63 | MP0000490_abnormal_crypts_of | 1.06918066 |
| 64 | MP0001849_ear_inflammation | 1.06659707 |
| 65 | MP0003690_abnormal_glial_cell | 1.02512957 |
| 66 | MP0003091_abnormal_cell_migration | 0.99644662 |
| 67 | MP0005166_decreased_susceptibility_to | 0.99622278 |
| 68 | MP0009764_decreased_sensitivity_to | 0.98897633 |
| 69 | MP0002277_abnormal_respiratory_mucosa | 0.95527390 |
| 70 | MP0000604_amyloidosis | 0.94286122 |
| 71 | MP0003448_altered_tumor_morphology | 0.90230094 |
| 72 | MP0002933_joint_inflammation | 0.88750284 |
| 73 | MP0001853_heart_inflammation | 0.87625197 |
| 74 | MP0004185_abnormal_adipocyte_glucose | 0.87587638 |
| 75 | MP0004808_abnormal_hematopoietic_stem | 0.86950350 |
| 76 | MP0005164_abnormal_response_to | 0.86435452 |
| 77 | MP0005390_skeleton_phenotype | 0.86255668 |
| 78 | MP0001663_abnormal_digestive_system | 0.85321495 |
| 79 | MP0004858_abnormal_nervous_system | 0.84366769 |
| 80 | MP0008874_decreased_physiological_sensi | 0.83567549 |
| 81 | MP0003566_abnormal_cell_adhesion | 0.80868695 |
| 82 | MP0002166_altered_tumor_susceptibility | 0.80559290 |
| 83 | MP0005409_darkened_coat_color | 0.75827297 |
| 84 | MP0003045_fibrosis | 0.75607517 |
| 85 | MP0003329_amyloid_beta_deposits | 0.73622198 |
| 86 | MP0003795_abnormal_bone_structure | 0.70382871 |
| 87 | MP0008004_abnormal_stomach_pH | 0.68584245 |
| 88 | MP0000678_abnormal_parathyroid_gland | 0.67858959 |
| 89 | MP0000343_altered_response_to | 0.67116648 |
| 90 | MP0000015_abnormal_ear_pigmentation | 0.66381753 |
| 91 | MP0002138_abnormal_hepatobiliary_system | 0.66251272 |
| 92 | MP0000249_abnormal_blood_vessel | 0.63419412 |
| 93 | MP0009763_increased_sensitivity_to | 0.62769793 |
| 94 | MP0001348_abnormal_lacrimal_gland | 0.61642259 |
| 95 | MP0001986_abnormal_taste_sensitivity | 0.60955829 |
| 96 | MP0010234_abnormal_vibrissa_follicle | 0.60617094 |
| 97 | MP0001958_emphysema | 0.58029757 |
| 98 | MP0003279_aneurysm | 0.57512198 |
| 99 | MP0005083_abnormal_biliary_tract | 0.57496706 |
| 100 | MP0003656_abnormal_erythrocyte_physiolo | 0.57065609 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Eczematoid dermatitis (HP:0000976) | 6.22652421 |
| 2 | Recurrent abscess formation (HP:0002722) | 5.16416344 |
| 3 | Recurrent bacterial skin infections (HP:0005406) | 5.03181440 |
| 4 | Abnormality of macrophages (HP:0004311) | 4.80590058 |
| 5 | Myositis (HP:0100614) | 4.57026142 |
| 6 | Orchitis (HP:0100796) | 4.14274034 |
| 7 | Recurrent gram-negative bacterial infections (HP:0005420) | 4.00142692 |
| 8 | Retrobulbar optic neuritis (HP:0100654) | 3.65132014 |
| 9 | Optic neuritis (HP:0100653) | 3.65132014 |
| 10 | Gastrointestinal infarctions (HP:0005244) | 3.62496427 |
| 11 | Chronic obstructive pulmonary disease (HP:0006510) | 3.60790188 |
| 12 | Obstructive lung disease (HP:0006536) | 3.60790188 |
| 13 | Recurrent fungal infections (HP:0002841) | 3.60737109 |
| 14 | Spontaneous hematomas (HP:0007420) | 3.59672272 |
| 15 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.54197428 |
| 16 | Mediastinal lymphadenopathy (HP:0100721) | 3.50492882 |
| 17 | Increased IgE level (HP:0003212) | 3.46832347 |
| 18 | Stomatitis (HP:0010280) | 3.44652637 |
| 19 | Meningitis (HP:0001287) | 3.40229309 |
| 20 | Recurrent skin infections (HP:0001581) | 3.33087019 |
| 21 | Gingivitis (HP:0000230) | 3.25810430 |
| 22 | Cellulitis (HP:0100658) | 3.22516089 |
| 23 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.17602148 |
| 24 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.97091099 |
| 25 | Recurrent cutaneous fungal infections (HP:0011370) | 2.97091099 |
| 26 | Prolonged bleeding time (HP:0003010) | 2.93637068 |
| 27 | Vasculitis (HP:0002633) | 2.90380808 |
| 28 | Pustule (HP:0200039) | 2.86940279 |
| 29 | Urticaria (HP:0001025) | 2.85832044 |
| 30 | Gastrointestinal inflammation (HP:0004386) | 2.80677516 |
| 31 | Encephalitis (HP:0002383) | 2.74143597 |
| 32 | Hypochromic anemia (HP:0001931) | 2.72414358 |
| 33 | Inflammation of the large intestine (HP:0002037) | 2.71588657 |
| 34 | Petechiae (HP:0000967) | 2.68157004 |
| 35 | Chest pain (HP:0100749) | 2.66091703 |
| 36 | Recurrent viral infections (HP:0004429) | 2.58174907 |
| 37 | Keratoconjunctivitis sicca (HP:0001097) | 2.57803274 |
| 38 | Epistaxis (HP:0000421) | 2.54555545 |
| 39 | Colitis (HP:0002583) | 2.53847036 |
| 40 | Hemoptysis (HP:0002105) | 2.47073558 |
| 41 | Hypochromic microcytic anemia (HP:0004840) | 2.44854062 |
| 42 | Increased cerebral lipofuscin (HP:0011813) | 2.44174407 |
| 43 | Gingival bleeding (HP:0000225) | 2.41566305 |
| 44 | Dysostosis multiplex (HP:0000943) | 2.38015685 |
| 45 | Peritonitis (HP:0002586) | 2.37702525 |
| 46 | Pulmonary infiltrates (HP:0002113) | 2.37343152 |
| 47 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.34858464 |
| 48 | Keratoconjunctivitis (HP:0001096) | 2.32490821 |
| 49 | Loss of speech (HP:0002371) | 2.31588356 |
| 50 | Osteomyelitis (HP:0002754) | 2.31442728 |
| 51 | Episodic fever (HP:0001954) | 2.28491721 |
| 52 | Anorexia (HP:0002039) | 2.27857464 |
| 53 | Arterial thrombosis (HP:0004420) | 2.26531428 |
| 54 | Abnormality of glycolipid metabolism (HP:0010969) | 2.25979101 |
| 55 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.25979101 |
| 56 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.25979101 |
| 57 | Panhypogammaglobulinemia (HP:0003139) | 2.25788989 |
| 58 | T lymphocytopenia (HP:0005403) | 2.25638999 |
| 59 | Pulmonary embolism (HP:0002204) | 2.25565111 |
| 60 | Slow saccadic eye movements (HP:0000514) | 2.24750418 |
| 61 | Purpura (HP:0000979) | 2.18080450 |
| 62 | Amyloidosis (HP:0011034) | 2.17447871 |
| 63 | Malnutrition (HP:0004395) | 2.15018844 |
| 64 | Lymphopenia (HP:0001888) | 2.13706856 |
| 65 | Thin bony cortex (HP:0002753) | 2.09652509 |
| 66 | Sepsis (HP:0100806) | 2.07916260 |
| 67 | Obstructive sleep apnea (HP:0002870) | 2.07398893 |
| 68 | Gastrointestinal stroma tumor (HP:0100723) | 2.06660010 |
| 69 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.05434927 |
| 70 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.05044993 |
| 71 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.05044993 |
| 72 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.05044993 |
| 73 | Abnormality of T cell number (HP:0011839) | 2.04462900 |
| 74 | Granulocytopenia (HP:0001913) | 2.01413277 |
| 75 | Hemorrhage of the eye (HP:0011885) | 2.00364863 |
| 76 | Increased serum ferritin (HP:0003281) | 1.99481137 |
| 77 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.98561287 |
| 78 | Hypergammaglobulinemia (HP:0010702) | 1.97368106 |
| 79 | Mucopolysacchariduria (HP:0008155) | 1.96842040 |
| 80 | Urinary glycosaminoglycan excretion (HP:0003541) | 1.96842040 |
| 81 | Premature loss of primary teeth (HP:0006323) | 1.96483101 |
| 82 | Increased IgM level (HP:0003496) | 1.96323099 |
| 83 | Hepatosplenomegaly (HP:0001433) | 1.95999588 |
| 84 | Leukocytosis (HP:0001974) | 1.95950184 |
| 85 | Microcytic anemia (HP:0001935) | 1.95623976 |
| 86 | Metaphyseal cupping (HP:0003021) | 1.94092061 |
| 87 | Abnormality of T cells (HP:0002843) | 1.91712216 |
| 88 | Segmental peripheral demyelination/remyelination (HP:0003481) | 1.91707639 |
| 89 | Abnormality of the peritoneum (HP:0002585) | 1.91436763 |
| 90 | Polygenic inheritance (HP:0010982) | 1.89388357 |
| 91 | Systemic lupus erythematosus (HP:0002725) | 1.88368450 |
| 92 | Emphysema (HP:0002097) | 1.88098604 |
| 93 | Skin ulcer (HP:0200042) | 1.87410316 |
| 94 | Polycythemia (HP:0001901) | 1.87397979 |
| 95 | Abnormality of the fingertips (HP:0001211) | 1.87198040 |
| 96 | Neuronal loss in central nervous system (HP:0002529) | 1.85771694 |
| 97 | Restrictive lung disease (HP:0002091) | 1.85656951 |
| 98 | Acne (HP:0001061) | 1.83458760 |
| 99 | Papilloma (HP:0012740) | 1.82114936 |
| 100 | Verrucae (HP:0200043) | 1.82114936 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK4 | 3.97046207 |
| 2 | ERN1 | 3.65814356 |
| 3 | MAP4K1 | 3.44882715 |
| 4 | TRIB3 | 3.17729882 |
| 5 | PRPF4B | 3.06000616 |
| 6 | MAP2K3 | 2.88747139 |
| 7 | IRAK4 | 2.54601678 |
| 8 | BLK | 2.50870319 |
| 9 | TYK2 | 2.40301144 |
| 10 | TNK2 | 2.05443391 |
| 11 | CSK | 2.04206252 |
| 12 | SIK1 | 1.98583157 |
| 13 | SMG1 | 1.98026488 |
| 14 | MAP3K3 | 1.96217256 |
| 15 | GRK6 | 1.95856909 |
| 16 | EPHB1 | 1.90243494 |
| 17 | ZAP70 | 1.86590678 |
| 18 | TAOK1 | 1.80216766 |
| 19 | FES | 1.75273165 |
| 20 | MAP3K11 | 1.74413171 |
| 21 | JAK3 | 1.59596193 |
| 22 | SIK3 | 1.58032430 |
| 23 | MAP3K13 | 1.57190211 |
| 24 | BTK | 1.44775105 |
| 25 | MAP3K14 | 1.44365283 |
| 26 | FGFR4 | 1.36855059 |
| 27 | FGR | 1.35148899 |
| 28 | HCK | 1.35118653 |
| 29 | KSR2 | 1.34060799 |
| 30 | MAP3K1 | 1.33419857 |
| 31 | TBK1 | 1.32299402 |
| 32 | MARK2 | 1.30974506 |
| 33 | SIK2 | 1.30379660 |
| 34 | PTK6 | 1.24126707 |
| 35 | PRKD2 | 1.20188564 |
| 36 | CDK12 | 1.16967570 |
| 37 | SYK | 1.16352481 |
| 38 | TAOK2 | 1.12348776 |
| 39 | IKBKE | 1.10411134 |
| 40 | MAP3K10 | 1.10391947 |
| 41 | IRAK3 | 1.08062887 |
| 42 | JAK1 | 1.07351312 |
| 43 | PKN2 | 1.05694743 |
| 44 | JAK2 | 1.02321563 |
| 45 | RIPK1 | 0.98861240 |
| 46 | ICK | 0.97997160 |
| 47 | CDC42BPA | 0.97514488 |
| 48 | PDPK1 | 0.97033026 |
| 49 | IRAK2 | 0.95381186 |
| 50 | LYN | 0.93038763 |
| 51 | TXK | 0.90341301 |
| 52 | CSF1R | 0.90324933 |
| 53 | PDK1 | 0.88668240 |
| 54 | TESK2 | 0.88105488 |
| 55 | LCK | 0.86844882 |
| 56 | MAP3K6 | 0.83913440 |
| 57 | ITK | 0.82361685 |
| 58 | YES1 | 0.75682353 |
| 59 | MAPK12 | 0.75066455 |
| 60 | CAMKK1 | 0.74696032 |
| 61 | HIPK2 | 0.74220666 |
| 62 | FGFR3 | 0.73802857 |
| 63 | MAP3K7 | 0.71653146 |
| 64 | MARK3 | 0.66483179 |
| 65 | MAP3K2 | 0.65758418 |
| 66 | LRRK2 | 0.65723633 |
| 67 | IKBKB | 0.63208474 |
| 68 | RET | 0.62642188 |
| 69 | STK38 | 0.59315309 |
| 70 | RPS6KC1 | 0.58338650 |
| 71 | RPS6KL1 | 0.58338650 |
| 72 | MATK | 0.57304449 |
| 73 | STK10 | 0.57252711 |
| 74 | DYRK1B | 0.56896474 |
| 75 | IRAK1 | 0.56215210 |
| 76 | PAK4 | 0.54564022 |
| 77 | SGK3 | 0.53043054 |
| 78 | FYN | 0.51847285 |
| 79 | RPS6KA2 | 0.50229528 |
| 80 | MAP2K6 | 0.49238945 |
| 81 | BMX | 0.48747470 |
| 82 | MAPK7 | 0.48532394 |
| 83 | PRKG2 | 0.48513721 |
| 84 | TGFBR2 | 0.47301762 |
| 85 | KIT | 0.43860878 |
| 86 | RPS6KA6 | 0.42695072 |
| 87 | TTN | 0.42120577 |
| 88 | MAPK11 | 0.41544298 |
| 89 | STK11 | 0.39609846 |
| 90 | MAPKAPK2 | 0.39373239 |
| 91 | MAP2K2 | 0.38857779 |
| 92 | CDK4 | 0.37775960 |
| 93 | EEF2K | 0.37108586 |
| 94 | MAP3K8 | 0.36236051 |
| 95 | MAP2K4 | 0.32374023 |
| 96 | PRKCH | 0.31856693 |
| 97 | BMPR2 | 0.31307328 |
| 98 | PRKD1 | 0.30694731 |
| 99 | PTK2B | 0.28923984 |
| 100 | RAF1 | 0.28835264 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.71579964 |
| 2 | Leishmaniasis_Homo sapiens_hsa05140 | 2.45724465 |
| 3 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.30608789 |
| 4 | Other glycan degradation_Homo sapiens_hsa00511 | 2.28992852 |
| 5 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 2.13146410 |
| 6 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.09025229 |
| 7 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 2.05220856 |
| 8 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.89929536 |
| 9 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.89573220 |
| 10 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.87801234 |
| 11 | Tuberculosis_Homo sapiens_hsa05152 | 1.84254561 |
| 12 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.71171689 |
| 13 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.70591288 |
| 14 | Allograft rejection_Homo sapiens_hsa05330 | 1.69106770 |
| 15 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.67298357 |
| 16 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.62397272 |
| 17 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.57960919 |
| 18 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.53931229 |
| 19 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.52202877 |
| 20 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.49751966 |
| 21 | Measles_Homo sapiens_hsa05162 | 1.48167684 |
| 22 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.45585106 |
| 23 | Influenza A_Homo sapiens_hsa05164 | 1.39975304 |
| 24 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.39609427 |
| 25 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.39540877 |
| 26 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.38471389 |
| 27 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.37357489 |
| 28 | Malaria_Homo sapiens_hsa05144 | 1.36201765 |
| 29 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.33770444 |
| 30 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.28399812 |
| 31 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.26806713 |
| 32 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.25719179 |
| 33 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.22537740 |
| 34 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.22189603 |
| 35 | Viral myocarditis_Homo sapiens_hsa05416 | 1.21261864 |
| 36 | Hepatitis C_Homo sapiens_hsa05160 | 1.20713181 |
| 37 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.19302328 |
| 38 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.19186429 |
| 39 | Hepatitis B_Homo sapiens_hsa05161 | 1.18843462 |
| 40 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.18321187 |
| 41 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.17313457 |
| 42 | Phagosome_Homo sapiens_hsa04145 | 1.13040833 |
| 43 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.10387327 |
| 44 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.08393802 |
| 45 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.07221827 |
| 46 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.04654228 |
| 47 | Legionellosis_Homo sapiens_hsa05134 | 1.04445061 |
| 48 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.03852911 |
| 49 | Lysosome_Homo sapiens_hsa04142 | 1.03697307 |
| 50 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.01333208 |
| 51 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.00010543 |
| 52 | Endometrial cancer_Homo sapiens_hsa05213 | 0.99815995 |
| 53 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.97616425 |
| 54 | Platelet activation_Homo sapiens_hsa04611 | 0.97285028 |
| 55 | Shigellosis_Homo sapiens_hsa05131 | 0.97036530 |
| 56 | Apoptosis_Homo sapiens_hsa04210 | 0.96884326 |
| 57 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.95755137 |
| 58 | Salmonella infection_Homo sapiens_hsa05132 | 0.95449616 |
| 59 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.94576085 |
| 60 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.93661389 |
| 61 | Endocytosis_Homo sapiens_hsa04144 | 0.93610652 |
| 62 | Pertussis_Homo sapiens_hsa05133 | 0.92592059 |
| 63 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.91753239 |
| 64 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.90211151 |
| 65 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.90058130 |
| 66 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.85608025 |
| 67 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.85025920 |
| 68 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.82096999 |
| 69 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.79198506 |
| 70 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.75519628 |
| 71 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.72155299 |
| 72 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.71273810 |
| 73 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.70157509 |
| 74 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.69429356 |
| 75 | Colorectal cancer_Homo sapiens_hsa05210 | 0.69008381 |
| 76 | Amoebiasis_Homo sapiens_hsa05146 | 0.68836495 |
| 77 | Insulin resistance_Homo sapiens_hsa04931 | 0.68154935 |
| 78 | Glioma_Homo sapiens_hsa05214 | 0.68134812 |
| 79 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.67910182 |
| 80 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.65980408 |
| 81 | Bladder cancer_Homo sapiens_hsa05219 | 0.64523685 |
| 82 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.64310032 |
| 83 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.63542694 |
| 84 | HTLV-I infection_Homo sapiens_hsa05166 | 0.63154613 |
| 85 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.63045819 |
| 86 | Thyroid cancer_Homo sapiens_hsa05216 | 0.61494104 |
| 87 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.61173108 |
| 88 | Asthma_Homo sapiens_hsa05310 | 0.58741440 |
| 89 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.57350898 |
| 90 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.56207756 |
| 91 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.56114228 |
| 92 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.56056355 |
| 93 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.55515659 |
| 94 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.54660231 |
| 95 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.54440859 |
| 96 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.53935375 |
| 97 | Prostate cancer_Homo sapiens_hsa05215 | 0.53405209 |
| 98 | Prion diseases_Homo sapiens_hsa05020 | 0.52828571 |
| 99 | Long-term potentiation_Homo sapiens_hsa04720 | 0.51689209 |
| 100 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.51602819 |

