Rank | Gene Set | Z-score |
---|---|---|
1 | L-phenylalanine catabolic process (GO:0006559) | 7.66209106 |
2 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 7.66209106 |
3 | L-phenylalanine metabolic process (GO:0006558) | 7.33372824 |
4 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 7.33372824 |
5 | epoxygenase P450 pathway (GO:0019373) | 7.01526049 |
6 | aromatic amino acid family catabolic process (GO:0009074) | 6.90435582 |
7 | exogenous drug catabolic process (GO:0042738) | 6.60413147 |
8 | omega-hydroxylase P450 pathway (GO:0097267) | 6.53708085 |
9 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 6.42588656 |
10 | indole-containing compound catabolic process (GO:0042436) | 6.23732968 |
11 | indolalkylamine catabolic process (GO:0046218) | 6.23732968 |
12 | tryptophan catabolic process (GO:0006569) | 6.23732968 |
13 | kynurenine metabolic process (GO:0070189) | 6.09133691 |
14 | bile acid biosynthetic process (GO:0006699) | 6.01971057 |
15 | regulation of plasminogen activation (GO:0010755) | 5.99677052 |
16 | tryptophan metabolic process (GO:0006568) | 5.86919773 |
17 | glyoxylate metabolic process (GO:0046487) | 5.81507201 |
18 | urea metabolic process (GO:0019627) | 5.68277631 |
19 | urea cycle (GO:0000050) | 5.68277631 |
20 | high-density lipoprotein particle remodeling (GO:0034375) | 5.66590730 |
21 | alpha-linolenic acid metabolic process (GO:0036109) | 5.62490747 |
22 | negative regulation of fibrinolysis (GO:0051918) | 5.60633887 |
23 | drug metabolic process (GO:0017144) | 5.46457692 |
24 | regulation of fibrinolysis (GO:0051917) | 5.40724991 |
25 | protein carboxylation (GO:0018214) | 5.40402398 |
26 | peptidyl-glutamic acid carboxylation (GO:0017187) | 5.40402398 |
27 | sulfur amino acid catabolic process (GO:0000098) | 5.38683932 |
28 | cysteine metabolic process (GO:0006534) | 5.36747114 |
29 | oxidative demethylation (GO:0070989) | 5.27221594 |
30 | nitrogen cycle metabolic process (GO:0071941) | 5.22967955 |
31 | serine family amino acid catabolic process (GO:0009071) | 5.16282794 |
32 | bile acid metabolic process (GO:0008206) | 5.13514147 |
33 | * regulation of protein activation cascade (GO:2000257) | 5.08100168 |
34 | acute-phase response (GO:0006953) | 5.04028486 |
35 | aromatic amino acid family metabolic process (GO:0009072) | 5.02086087 |
36 | regulation of cholesterol esterification (GO:0010872) | 4.94608617 |
37 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 4.91702759 |
38 | reverse cholesterol transport (GO:0043691) | 4.90831109 |
39 | regulation of triglyceride catabolic process (GO:0010896) | 4.90071127 |
40 | phenylpropanoid metabolic process (GO:0009698) | 4.87599613 |
41 | * complement activation, alternative pathway (GO:0006957) | 4.86915816 |
42 | tyrosine metabolic process (GO:0006570) | 4.84806140 |
43 | positive regulation of fatty acid biosynthetic process (GO:0045723) | 4.81471335 |
44 | plasma lipoprotein particle remodeling (GO:0034369) | 4.81418848 |
45 | protein-lipid complex remodeling (GO:0034368) | 4.81418848 |
46 | macromolecular complex remodeling (GO:0034367) | 4.81418848 |
47 | negative regulation of hemostasis (GO:1900047) | 4.79537970 |
48 | negative regulation of blood coagulation (GO:0030195) | 4.79537970 |
49 | homocysteine metabolic process (GO:0050667) | 4.72766396 |
50 | * regulation of complement activation (GO:0030449) | 4.69125641 |
51 | alpha-amino acid catabolic process (GO:1901606) | 4.68526810 |
52 | negative regulation of cholesterol transport (GO:0032375) | 4.67729801 |
53 | negative regulation of sterol transport (GO:0032372) | 4.67729801 |
54 | triglyceride homeostasis (GO:0070328) | 4.67006421 |
55 | acylglycerol homeostasis (GO:0055090) | 4.67006421 |
56 | phospholipid efflux (GO:0033700) | 4.65535198 |
57 | lysine catabolic process (GO:0006554) | 4.62192806 |
58 | lysine metabolic process (GO:0006553) | 4.62192806 |
59 | amino-acid betaine metabolic process (GO:0006577) | 4.58929954 |
60 | cellular ketone body metabolic process (GO:0046950) | 4.50638976 |
61 | coenzyme catabolic process (GO:0009109) | 4.48464699 |
62 | glycine metabolic process (GO:0006544) | 4.47530059 |
63 | negative regulation of wound healing (GO:0061045) | 4.44623384 |
64 | * regulation of humoral immune response (GO:0002920) | 4.43732566 |
65 | bile acid and bile salt transport (GO:0015721) | 4.43555266 |
66 | imidazole-containing compound metabolic process (GO:0052803) | 4.42471550 |
67 | indolalkylamine metabolic process (GO:0006586) | 4.42408568 |
68 | plasma lipoprotein particle clearance (GO:0034381) | 4.41864050 |
69 | alkaloid metabolic process (GO:0009820) | 4.40873667 |
70 | negative regulation of coagulation (GO:0050819) | 4.38742348 |
71 | negative regulation of protein activation cascade (GO:2000258) | 4.38493891 |
72 | amine catabolic process (GO:0009310) | 4.32985657 |
73 | cellular biogenic amine catabolic process (GO:0042402) | 4.32985657 |
74 | cellular amino acid catabolic process (GO:0009063) | 4.30668973 |
75 | cellular glucuronidation (GO:0052695) | 4.28670392 |
76 | ethanol metabolic process (GO:0006067) | 4.24875815 |
77 | glutamate metabolic process (GO:0006536) | 4.24375413 |
78 | cholesterol efflux (GO:0033344) | 4.24009809 |
79 | serine family amino acid metabolic process (GO:0009069) | 4.21758078 |
80 | benzene-containing compound metabolic process (GO:0042537) | 4.15609297 |
81 | ethanol oxidation (GO:0006069) | 4.15567917 |
82 | positive regulation of blood coagulation (GO:0030194) | 4.07698074 |
83 | positive regulation of hemostasis (GO:1900048) | 4.07698074 |
84 | opsonization (GO:0008228) | 4.07250791 |
85 | cellular modified amino acid catabolic process (GO:0042219) | 4.06963633 |
86 | arginine metabolic process (GO:0006525) | 4.05578110 |
87 | serine family amino acid biosynthetic process (GO:0009070) | 4.04510379 |
88 | aldehyde catabolic process (GO:0046185) | 4.04210012 |
89 | dicarboxylic acid biosynthetic process (GO:0043650) | 4.03944705 |
90 | low-density lipoprotein particle remodeling (GO:0034374) | 4.03536562 |
91 | plasma lipoprotein particle assembly (GO:0034377) | 4.02592190 |
92 | acute inflammatory response (GO:0002526) | 4.00182158 |
93 | fibrinolysis (GO:0042730) | 3.98711970 |
94 | drug catabolic process (GO:0042737) | 3.91370694 |
95 | ketone body metabolic process (GO:1902224) | 3.90286112 |
96 | blood coagulation, intrinsic pathway (GO:0007597) | 3.85861059 |
97 | positive regulation of triglyceride metabolic process (GO:0090208) | 3.85552167 |
98 | positive regulation of triglyceride lipase activity (GO:0061365) | 3.84768993 |
99 | positive regulation of lipoprotein lipase activity (GO:0051006) | 3.84768993 |
100 | cofactor catabolic process (GO:0051187) | 3.84265737 |
101 | proline metabolic process (GO:0006560) | 3.81410198 |
102 | glucuronate metabolic process (GO:0019585) | 3.80491931 |
103 | uronic acid metabolic process (GO:0006063) | 3.80491931 |
104 | flavonoid metabolic process (GO:0009812) | 3.80081921 |
105 | protein-lipid complex subunit organization (GO:0071825) | 3.79414799 |
106 | negative regulation of lipase activity (GO:0060192) | 3.79019006 |
107 | very-low-density lipoprotein particle assembly (GO:0034379) | 3.78409502 |
108 | organic acid catabolic process (GO:0016054) | 3.76774712 |
109 | carboxylic acid catabolic process (GO:0046395) | 3.76774712 |
110 | positive regulation of coagulation (GO:0050820) | 3.75039251 |
111 | positive regulation of lipid catabolic process (GO:0050996) | 3.74548463 |
112 | cholesterol homeostasis (GO:0042632) | 3.74136089 |
113 | regulation of bile acid biosynthetic process (GO:0070857) | 3.70683576 |
114 | short-chain fatty acid metabolic process (GO:0046459) | 3.69981236 |
115 | regulation of apoptotic cell clearance (GO:2000425) | 3.69945187 |
116 | acetyl-CoA metabolic process (GO:0006084) | 3.69718918 |
117 | phospholipid homeostasis (GO:0055091) | 3.69031529 |
118 | sterol homeostasis (GO:0055092) | 3.67870961 |
119 | regulation of lipoprotein particle clearance (GO:0010984) | 3.67786782 |
120 | plasma lipoprotein particle organization (GO:0071827) | 3.64540817 |
121 | regulation of cholesterol homeostasis (GO:2000188) | 3.62525483 |
122 | NAD biosynthetic process (GO:0009435) | 3.62445575 |
123 | negative regulation of complement activation (GO:0045916) | 3.61843781 |
124 | * protein activation cascade (GO:0072376) | 3.60894277 |
125 | protein-lipid complex assembly (GO:0065005) | 3.60639770 |
126 | pyridine nucleotide biosynthetic process (GO:0019363) | 3.58260198 |
127 | nicotinamide nucleotide biosynthetic process (GO:0019359) | 3.58260198 |
128 | * complement activation (GO:0006956) | 3.56967820 |
129 | * complement activation, classical pathway (GO:0006958) | 3.56943666 |
130 | S-adenosylmethionine metabolic process (GO:0046500) | 3.56097763 |
131 | hormone catabolic process (GO:0042447) | 3.51566138 |
132 | positive regulation of heterotypic cell-cell adhesion (GO:0034116) | 3.51061142 |
133 | intestinal cholesterol absorption (GO:0030299) | 3.48326071 |
134 | response to phenylpropanoid (GO:0080184) | 3.47122293 |
135 | regulation of triglyceride metabolic process (GO:0090207) | 3.46042624 |
136 | arginine catabolic process (GO:0006527) | 3.42341237 |
Rank | Gene Set | Z-score |
---|---|---|
1 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 8.42407015 |
2 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 7.22960313 |
3 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 7.10238469 |
4 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 6.49533060 |
5 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 5.28540569 |
6 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 5.15103241 |
7 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 4.86841898 |
8 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 4.05428518 |
9 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 4.01175113 |
10 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 2.31586766 |
11 | TCF7L2_21901280_ChIP-Seq_H4IIE_Rat | 2.07127920 |
12 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 12.0154885 |
13 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.98866372 |
14 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.98325010 |
15 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.62942361 |
16 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.58349383 |
17 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.57454351 |
18 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.49324520 |
19 | GATA1_22025678_ChIP-Seq_K562_Human | 1.40247688 |
20 | HNF4A_19822575_ChIP-Seq_HepG2_Human | 1.39801114 |
21 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.32394038 |
22 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.32350516 |
23 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.26745421 |
24 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.24343921 |
25 | RXRA_24833708_ChIP-Seq_LIVER_Mouse | 1.22675418 |
26 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.16688907 |
27 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.14277507 |
28 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.11274825 |
29 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.08923378 |
30 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.07105553 |
31 | P68_20966046_ChIP-Seq_HELA_Human | 1.06663527 |
32 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.04620216 |
33 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.04458160 |
34 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.03924345 |
35 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.03902182 |
36 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.02931006 |
37 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.02006517 |
38 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.00710852 |
39 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.00350551 |
40 | SA1_27219007_Chip-Seq_Bcells_Human | 1.00181404 |
41 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.98541797 |
42 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.97445642 |
43 | RACK7_27058665_Chip-Seq_MCF-7_Human | 0.92151338 |
44 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 0.90276073 |
45 | PHF8_20622854_ChIP-Seq_HELA_Human | 0.88739596 |
46 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.88231808 |
47 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 0.87947259 |
48 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.87760599 |
49 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.86383807 |
50 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 0.83821745 |
51 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 0.83144467 |
52 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.82861241 |
53 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.82712479 |
54 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.81968749 |
55 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.81740963 |
56 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.80857488 |
57 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 0.80661374 |
58 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 0.80462767 |
59 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.80197078 |
60 | GATA4_25053715_ChIP-Seq_YYC3_Human | 0.78772825 |
61 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 0.77786809 |
62 | SOX2_21211035_ChIP-Seq_LN229_Human | 0.76954768 |
63 | * ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.76950076 |
64 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.76542866 |
65 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 0.76534170 |
66 | RARA_24833708_ChIP-Seq_LIVER_Mouse | 0.76495381 |
67 | JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse | 0.75201368 |
68 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.74850905 |
69 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.71543342 |
70 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.70439558 |
71 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.70381196 |
72 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.69956777 |
73 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.69208618 |
74 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.68920880 |
75 | RARB_24833708_ChIP-Seq_LIVER_Mouse | 0.67672580 |
76 | GATA3_21867929_ChIP-Seq_CD8_Mouse | 0.67661844 |
77 | VDR_21846776_ChIP-Seq_THP-1_Human | 0.66324891 |
78 | P300_27268052_Chip-Seq_Bcells_Human | 0.65400184 |
79 | SMC3_22415368_ChIP-Seq_MEFs_Mouse | 0.65187477 |
80 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.64855043 |
81 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.64241380 |
82 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.63930669 |
83 | CREB1_26743006_Chip-Seq_LNCaP_Human | 0.63893976 |
84 | * ERA_21632823_ChIP-Seq_H3396_Human | 0.63778205 |
85 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.63278101 |
86 | P63_20808887_ChIP-Seq_KERATINOCYTES_Human | 0.62588575 |
87 | CTCF_21964334_ChIP-Seq_BJAB-B_Human | 0.62537689 |
88 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 0.62119657 |
89 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.61711479 |
90 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.60931187 |
91 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.60794505 |
92 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.60794505 |
93 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 0.60743923 |
94 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 0.60722366 |
95 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.60588163 |
96 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 0.60261829 |
97 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.59827024 |
98 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.59266482 |
99 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.58118434 |
100 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.53844703 |
101 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.53689005 |
102 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.53509375 |
103 | AR_20517297_ChIP-Seq_VCAP_Human | 0.53421454 |
104 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.53099553 |
105 | MYC_19915707_ChIP-ChIP_AK7_Human | 0.52594141 |
106 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 0.51866074 |
107 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 0.51519840 |
108 | ESET_19884257_ChIP-Seq_ESCs_Mouse | 0.50564271 |
109 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.50373812 |
110 | STAT1_17558387_ChIP-Seq_HELA_Human | 0.48857559 |
111 | FOXA1_26743006_Chip-Seq_LNCaP-abl_Human | 0.48751480 |
112 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.48596748 |
113 | CBP_21632823_ChIP-Seq_H3396_Human | 0.47576602 |
114 | PPARG_20887899_ChIP-Seq_3T3-L1_Mouse | 0.45431600 |
115 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.44680709 |
116 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.44146331 |
117 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.43396931 |
118 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.42971607 |
119 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.42603446 |
120 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.41953561 |
121 | GATA1_19941826_ChIP-Seq_K562_Human | 0.39918961 |
122 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.39811994 |
123 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 0.39731977 |
124 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.39670075 |
125 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.38520761 |
126 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.38408354 |
127 | STAT3_19079543_ChIP-ChIP_MESCs_Mouse | 0.38396241 |
128 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.38030290 |
129 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.37838196 |
130 | SPI1_26923725_Chip-Seq_HPCs_Mouse | 0.37705740 |
131 | GATA2_19941826_ChIP-Seq_K562_Human | 0.37624608 |
132 | MYC_27129775_Chip-Seq_CORNEA_Mouse | 0.37514101 |
133 | LUZP1_20508642_ChIP-Seq_ESCs_Mouse | 0.37337100 |
134 | GATA6_25053715_ChIP-Seq_YYC3_Human | 0.36572186 |
135 | CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.36204100 |
136 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.36044220 |
137 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.35883283 |
138 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.35270301 |
139 | NCOR_22424771_ChIP-Seq_293T_Human | 0.34443760 |
140 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 0.34342111 |
141 | SOX3_22085726_ChIP-Seq_MUSCLE_Mouse | 0.33888818 |
142 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.33485622 |
143 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.33034734 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0002139_abnormal_hepatobiliary_system | 8.40786169 |
2 | MP0005360_urolithiasis | 7.55913441 |
3 | MP0005085_abnormal_gallbladder_physiolo | 6.43787531 |
4 | MP0005365_abnormal_bile_salt | 6.19286867 |
5 | MP0008875_abnormal_xenobiotic_pharmacok | 5.14064382 |
6 | MP0003806_abnormal_nucleotide_metabolis | 4.32874836 |
7 | MP0003252_abnormal_bile_duct | 3.89626798 |
8 | MP0010329_abnormal_lipoprotein_level | 3.60015437 |
9 | MP0009840_abnormal_foam_cell | 3.33787557 |
10 | MP0005083_abnormal_biliary_tract | 3.02016886 |
11 | MP0003195_calcinosis | 2.83400282 |
12 | MP0005332_abnormal_amino_acid | 2.76233242 |
13 | MP0001666_abnormal_nutrient_absorption | 2.60102316 |
14 | MP0003191_abnormal_cellular_cholesterol | 2.29660242 |
15 | MP0000609_abnormal_liver_physiology | 2.15869394 |
16 | MP0004019_abnormal_vitamin_homeostasis | 2.12298088 |
17 | MP0002118_abnormal_lipid_homeostasis | 2.10734629 |
18 | MP0003868_abnormal_feces_composition | 1.94839427 |
19 | MP0002138_abnormal_hepatobiliary_system | 1.94695579 |
20 | MP0005319_abnormal_enzyme/_coenzyme | 1.83535428 |
21 | MP0001764_abnormal_homeostasis | 1.70155840 |
22 | MP0009697_abnormal_copulation | 1.62773472 |
23 | MP0005584_abnormal_enzyme/coenzyme_acti | 1.57425931 |
24 | MP0005451_abnormal_body_composition | 1.45187168 |
25 | MP0003011_delayed_dark_adaptation | 1.36105331 |
26 | MP0003186_abnormal_redox_activity | 1.28015840 |
27 | MP0003656_abnormal_erythrocyte_physiolo | 1.24852348 |
28 | MP0009643_abnormal_urine_homeostasis | 1.23603158 |
29 | MP0000598_abnormal_liver_morphology | 1.17089750 |
30 | MP0003879_abnormal_hair_cell | 1.16980822 |
31 | MP0005647_abnormal_sex_gland | 1.16697198 |
32 | MP0003705_abnormal_hypodermis_morpholog | 1.11116087 |
33 | MP0000604_amyloidosis | 1.07833193 |
34 | MP0009764_decreased_sensitivity_to | 1.05595199 |
35 | MP0009763_increased_sensitivity_to | 1.01719697 |
36 | MP0002254_reproductive_system_inflammat | 0.97078447 |
37 | MP0010368_abnormal_lymphatic_system | 0.93769212 |
38 | MP0005636_abnormal_mineral_homeostasis | 0.93178461 |
39 | MP0008469_abnormal_protein_level | 0.89310097 |
40 | MP0009642_abnormal_blood_homeostasis | 0.87400250 |
41 | MP0006036_abnormal_mitochondrial_physio | 0.85670584 |
42 | MP0005408_hypopigmentation | 0.85044680 |
43 | MP0002876_abnormal_thyroid_physiology | 0.80847322 |
44 | MP0005376_homeostasis/metabolism_phenot | 0.80290563 |
45 | MP0002078_abnormal_glucose_homeostasis | 0.78327153 |
46 | MP0009765_abnormal_xenobiotic_induced | 0.78167589 |
47 | MP0005670_abnormal_white_adipose | 0.77859556 |
48 | MP0002089_abnormal_postnatal_growth/wei | 0.75514005 |
49 | MP0005084_abnormal_gallbladder_morpholo | 0.75010573 |
50 | MP0009785_altered_susceptibility_to | 0.73119910 |
51 | MP0005220_abnormal_exocrine_pancreas | 0.72493746 |
52 | MP0005167_abnormal_blood-brain_barrier | 0.72244928 |
53 | MP0002971_abnormal_brown_adipose | 0.71468157 |
54 | MP0005334_abnormal_fat_pad | 0.69252922 |
55 | MP0005535_abnormal_body_temperature | 0.67910437 |
56 | MP0004130_abnormal_muscle_cell | 0.65954072 |
57 | MP0005266_abnormal_metabolism | 0.65808179 |
58 | MP0001915_intracranial_hemorrhage | 0.65728486 |
59 | MP0003690_abnormal_glial_cell | 0.65416364 |
60 | MP0001661_extended_life_span | 0.64936533 |
61 | MP0002249_abnormal_larynx_morphology | 0.63727425 |
62 | MP0009053_abnormal_anal_canal | 0.63322372 |
63 | MP0003329_amyloid_beta_deposits | 0.63257517 |
64 | MP0000639_abnormal_adrenal_gland | 0.60594158 |
65 | MP0006035_abnormal_mitochondrial_morpho | 0.58422763 |
66 | MP0001756_abnormal_urination | 0.57955643 |
67 | MP0005448_abnormal_energy_balance | 0.55044297 |
68 | MP0005464_abnormal_platelet_physiology | 0.52570576 |
69 | MP0002282_abnormal_trachea_morphology | 0.51450818 |
70 | MP0002822_catalepsy | 0.51011629 |
71 | MP0000566_synostosis | 0.47978307 |
72 | MP0005395_other_phenotype | 0.47242612 |
73 | MP0010386_abnormal_urinary_bladder | 0.47176607 |
74 | MP0002332_abnormal_exercise_endurance | 0.46700280 |
75 | MP0003638_abnormal_response/metabolism_ | 0.46654315 |
76 | MP0003718_maternal_effect | 0.46565715 |
77 | MP0002928_abnormal_bile_duct | 0.45651274 |
78 | MP0008874_decreased_physiological_sensi | 0.45446143 |
79 | MP0008873_increased_physiological_sensi | 0.45209246 |
80 | MP0005187_abnormal_penis_morphology | 0.44652356 |
81 | MP0002136_abnormal_kidney_physiology | 0.44113195 |
82 | MP0002837_dystrophic_cardiac_calcinosis | 0.43253237 |
83 | MP0004782_abnormal_surfactant_physiolog | 0.42692065 |
84 | MP0003953_abnormal_hormone_level | 0.41187241 |
85 | MP0003724_increased_susceptibility_to | 0.41087499 |
86 | MP0003436_decreased_susceptibility_to | 0.41053141 |
87 | MP0004381_abnormal_hair_follicle | 0.41009678 |
88 | MP0003075_altered_response_to | 0.39586881 |
89 | MP0005409_darkened_coat_color | 0.38994880 |
90 | MP0005248_abnormal_Harderian_gland | 0.38411541 |
91 | MP0008872_abnormal_physiological_respon | 0.38102182 |
92 | MP0005023_abnormal_wound_healing | 0.37956959 |
93 | MP0005166_decreased_susceptibility_to | 0.37822571 |
94 | MP0000003_abnormal_adipose_tissue | 0.36779867 |
95 | MP0009672_abnormal_birth_weight | 0.36578220 |
96 | MP0010155_abnormal_intestine_physiology | 0.36231308 |
97 | MP0005666_abnormal_adipose_tissue | 0.35211503 |
98 | MP0000467_abnormal_esophagus_morphology | 0.33462808 |
99 | MP0006082_CNS_inflammation | 0.33324743 |
100 | MP0003172_abnormal_lysosome_physiology | 0.32775928 |
101 | MP0009115_abnormal_fat_cell | 0.32630418 |
102 | MP0000579_abnormal_nail_morphology | 0.32293449 |
103 | MP0000249_abnormal_blood_vessel | 0.32001074 |
104 | MP0005375_adipose_tissue_phenotype | 0.31990054 |
105 | MP0001986_abnormal_taste_sensitivity | 0.31333236 |
106 | MP0002970_abnormal_white_adipose | 0.31257711 |
107 | MP0000230_abnormal_systemic_arterial | 0.31077255 |
108 | MP0002796_impaired_skin_barrier | 0.30641198 |
109 | MP0001243_abnormal_dermal_layer | 0.30403138 |
110 | MP0001853_heart_inflammation | 0.30132584 |
111 | MP0009333_abnormal_splenocyte_physiolog | 0.29984847 |
112 | MP0004883_abnormal_blood_vessel | 0.29442323 |
113 | MP0002168_other_aberrant_phenotype | 0.28812648 |
114 | MP0009384_cardiac_valve_regurgitation | 0.28675191 |
115 | MP0003183_abnormal_peptide_metabolism | 0.28444093 |
116 | MP0001845_abnormal_inflammatory_respons | 0.28097529 |
117 | MP0005025_abnormal_response_to | 0.27624338 |
118 | MP0001881_abnormal_mammary_gland | 0.26785092 |
119 | MP0002132_abnormal_respiratory_system | 0.24662672 |
120 | MP0005058_abnormal_lysosome_morphology | 0.23272212 |
121 | MP0005164_abnormal_response_to | 0.22955101 |
122 | MP0002090_abnormal_vision | 0.22423506 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 7.51149596 |
2 | Deep venous thrombosis (HP:0002625) | 7.43635323 |
3 | Intrahepatic cholestasis (HP:0001406) | 7.33039502 |
4 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 6.68970896 |
5 | Prolonged partial thromboplastin time (HP:0003645) | 6.58434067 |
6 | Hypobetalipoproteinemia (HP:0003563) | 6.50098363 |
7 | Xanthomatosis (HP:0000991) | 6.27245244 |
8 | Hyperlipoproteinemia (HP:0010980) | 5.68353928 |
9 | Complement deficiency (HP:0004431) | 5.34490382 |
10 | Hypolipoproteinemia (HP:0010981) | 4.80733357 |
11 | Joint hemorrhage (HP:0005261) | 4.80377793 |
12 | Hyperammonemia (HP:0001987) | 4.61842381 |
13 | Epidermoid cyst (HP:0200040) | 4.47825881 |
14 | Hyperglycinemia (HP:0002154) | 4.43885351 |
15 | Abnormality of the common coagulation pathway (HP:0010990) | 4.41799440 |
16 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 4.39859526 |
17 | Ketosis (HP:0001946) | 4.29502195 |
18 | Abnormality of methionine metabolism (HP:0010901) | 4.27173090 |
19 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 4.24407253 |
20 | Hypoalphalipoproteinemia (HP:0003233) | 4.16457334 |
21 | Fat malabsorption (HP:0002630) | 4.14318861 |
22 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 4.11923254 |
23 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 4.09493929 |
24 | Hyperglycinuria (HP:0003108) | 3.93710251 |
25 | Nephritis (HP:0000123) | 3.93270210 |
26 | Abnormality of serine family amino acid metabolism (HP:0010894) | 3.91863772 |
27 | Abnormality of glycine metabolism (HP:0010895) | 3.91863772 |
28 | Hypoglycemic coma (HP:0001325) | 3.90328804 |
29 | Abnormality of complement system (HP:0005339) | 3.89413995 |
30 | Abnormality of pyrimidine metabolism (HP:0004353) | 3.86088374 |
31 | Abnormality of the intrinsic pathway (HP:0010989) | 3.80380731 |
32 | Conjugated hyperbilirubinemia (HP:0002908) | 3.68076308 |
33 | Hypercholesterolemia (HP:0003124) | 3.60086828 |
34 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 3.44189774 |
35 | Abnormality of fatty-acid metabolism (HP:0004359) | 3.40259753 |
36 | Hyperbilirubinemia (HP:0002904) | 3.36018099 |
37 | Steatorrhea (HP:0002570) | 3.15762030 |
38 | Delayed CNS myelination (HP:0002188) | 3.13549352 |
39 | Abnormality of serum amino acid levels (HP:0003112) | 3.08818987 |
40 | Abnormality of nucleobase metabolism (HP:0010932) | 3.06717963 |
41 | Ketoacidosis (HP:0001993) | 3.05706056 |
42 | Hypochromic microcytic anemia (HP:0004840) | 2.97788305 |
43 | Spontaneous abortion (HP:0005268) | 2.96994093 |
44 | Hepatocellular carcinoma (HP:0001402) | 2.95675382 |
45 | Myocardial infarction (HP:0001658) | 2.92411907 |
46 | Purpura (HP:0000979) | 2.82443671 |
47 | Abnormality of the Achilles tendon (HP:0005109) | 2.79797126 |
48 | Metabolic acidosis (HP:0001942) | 2.78702248 |
49 | Skin nodule (HP:0200036) | 2.75562432 |
50 | Systemic lupus erythematosus (HP:0002725) | 2.70924468 |
51 | Abnormality of purine metabolism (HP:0004352) | 2.67032757 |
52 | Lethargy (HP:0001254) | 2.62277670 |
53 | Dicarboxylic aciduria (HP:0003215) | 2.62141160 |
54 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.62141160 |
55 | Vascular calcification (HP:0004934) | 2.59070657 |
56 | Hypoglycemic seizures (HP:0002173) | 2.49358068 |
57 | Abnormal gallbladder morphology (HP:0012437) | 2.49321284 |
58 | Acanthocytosis (HP:0001927) | 2.48092309 |
59 | Spastic diplegia (HP:0001264) | 2.47308029 |
60 | Cerebral edema (HP:0002181) | 2.43946318 |
61 | Gout (HP:0001997) | 2.42789521 |
62 | Mitral stenosis (HP:0001718) | 2.42609753 |
63 | Cholelithiasis (HP:0001081) | 2.42551590 |
64 | Abnormal gallbladder physiology (HP:0012438) | 2.39672062 |
65 | Cholecystitis (HP:0001082) | 2.39672062 |
66 | Glomerulonephritis (HP:0000099) | 2.37955189 |
67 | Neonatal onset (HP:0003623) | 2.36744025 |
68 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.36667710 |
69 | Irritability (HP:0000737) | 2.35243500 |
70 | Pulmonary embolism (HP:0002204) | 2.30650875 |
71 | Cardiovascular calcification (HP:0011915) | 2.29223795 |
72 | Malnutrition (HP:0004395) | 2.28335944 |
73 | Amyloidosis (HP:0011034) | 2.25540108 |
74 | Reduced antithrombin III activity (HP:0001976) | 2.22559294 |
75 | Brushfield spots (HP:0001088) | 2.18689083 |
76 | Increased serum ferritin (HP:0003281) | 2.17202916 |
77 | Gingival bleeding (HP:0000225) | 2.17150593 |
78 | Late onset (HP:0003584) | 2.16646019 |
79 | Sensorimotor neuropathy (HP:0007141) | 2.16164724 |
80 | Menorrhagia (HP:0000132) | 2.16002462 |
81 | Esophageal varix (HP:0002040) | 2.14932193 |
82 | Pancreatitis (HP:0001733) | 2.14144687 |
83 | Enlarged kidneys (HP:0000105) | 2.11422800 |
84 | Cerebral palsy (HP:0100021) | 2.10698070 |
85 | Vomiting (HP:0002013) | 2.08368602 |
86 | Generalized aminoaciduria (HP:0002909) | 2.06610542 |
87 | Opisthotonus (HP:0002179) | 2.06031393 |
88 | Thrombophlebitis (HP:0004418) | 2.06010539 |
89 | Fair hair (HP:0002286) | 2.03466125 |
90 | Hyperinsulinemic hypoglycemia (HP:0000825) | 2.03444562 |
91 | Retinal atrophy (HP:0001105) | 2.03025180 |
92 | Abnormality of the gallbladder (HP:0005264) | 2.02926905 |
93 | Hemorrhage of the eye (HP:0011885) | 2.00057728 |
94 | Poikilocytosis (HP:0004447) | 1.99228543 |
95 | Osteomalacia (HP:0002749) | 1.96913112 |
96 | Elevated alkaline phosphatase (HP:0003155) | 1.96460260 |
97 | Rickets (HP:0002748) | 1.92444436 |
98 | Abnormality of iron homeostasis (HP:0011031) | 1.90357724 |
99 | Gangrene (HP:0100758) | 1.90006390 |
100 | Renal cortical cysts (HP:0000803) | 1.89714430 |
101 | Abnormal cartilage morphology (HP:0002763) | 1.88172292 |
102 | Joint swelling (HP:0001386) | 1.87837951 |
103 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.87484474 |
104 | Arthropathy (HP:0003040) | 1.87064645 |
105 | Epistaxis (HP:0000421) | 1.86224269 |
106 | Abnormality of alkaline phosphatase activity (HP:0004379) | 1.85366753 |
107 | Hypophosphatemic rickets (HP:0004912) | 1.83159582 |
108 | Hydroxyprolinuria (HP:0003080) | 1.82298118 |
109 | Abnormality of proline metabolism (HP:0010907) | 1.82298118 |
110 | Elevated hepatic transaminases (HP:0002910) | 1.82050427 |
111 | Atrioventricular block (HP:0001678) | 1.81455811 |
112 | Abnormal enzyme/coenzyme activity (HP:0012379) | 1.80928229 |
113 | Alkalosis (HP:0001948) | 1.80261082 |
114 | Status epilepticus (HP:0002133) | 1.80129791 |
115 | Neonatal hypoglycemia (HP:0001998) | 1.78642397 |
116 | Abnormality of vitamin metabolism (HP:0100508) | 1.75381637 |
117 | Hyperphosphaturia (HP:0003109) | 1.74240898 |
118 | Hyperglycemia (HP:0003074) | 1.74115818 |
119 | Mucopolysacchariduria (HP:0008155) | 1.73908597 |
120 | Urinary glycosaminoglycan excretion (HP:0003541) | 1.73908597 |
121 | Increased purine levels (HP:0004368) | 1.73679900 |
122 | Hyperuricemia (HP:0002149) | 1.73679900 |
123 | J-shaped sella turcica (HP:0002680) | 1.72058490 |
124 | Potter facies (HP:0002009) | 1.71406834 |
125 | Facial shape deformation (HP:0011334) | 1.71406834 |
126 | Glycosuria (HP:0003076) | 1.70646004 |
127 | Abnormality of urine glucose concentration (HP:0011016) | 1.70646004 |
128 | Reticulocytosis (HP:0001923) | 1.70558403 |
129 | Abnormality of polysaccharide metabolism (HP:0011012) | 1.67603917 |
130 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 1.67603917 |
131 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 1.67603917 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BCKDK | 7.36236825 |
2 | SIK1 | 4.60936073 |
3 | FGFR4 | 4.60853316 |
4 | ERN1 | 4.46674294 |
5 | NTRK3 | 3.83404336 |
6 | TAOK3 | 3.08275007 |
7 | INSRR | 2.91191267 |
8 | ERBB4 | 2.82730665 |
9 | MAP2K4 | 2.40531419 |
10 | PKN2 | 2.29691467 |
11 | FLT3 | 2.03786325 |
12 | MST1R | 2.03039348 |
13 | PIK3CG | 1.90411261 |
14 | MAPK11 | 1.84774557 |
15 | TRIB3 | 1.78626282 |
16 | TYK2 | 1.72396796 |
17 | PRPF4B | 1.56847298 |
18 | LATS1 | 1.53416456 |
19 | ABL2 | 1.47652599 |
20 | DAPK2 | 1.47309500 |
21 | PTK6 | 1.46880485 |
22 | NEK9 | 1.36276496 |
23 | PDK2 | 1.32098890 |
24 | KDR | 1.32066318 |
25 | FRK | 1.30986017 |
26 | FGFR2 | 1.28874195 |
27 | JAK2 | 1.22003925 |
28 | PINK1 | 1.18704037 |
29 | MAP3K7 | 1.18057329 |
30 | MAP2K3 | 1.12525931 |
31 | PRKAA2 | 1.09368475 |
32 | TBK1 | 1.08429564 |
33 | GRK6 | 1.07959313 |
34 | ZAP70 | 1.07830192 |
35 | PIK3CA | 1.04485552 |
36 | MAPK15 | 1.00811006 |
37 | MAP3K14 | 0.99861551 |
38 | MAPK4 | 0.98554261 |
39 | JAK1 | 0.98495515 |
40 | MAP3K10 | 0.96466965 |
41 | ERBB2 | 0.94515299 |
42 | STK38L | 0.92085005 |
43 | MAP4K1 | 0.91912015 |
44 | PRKCZ | 0.91908932 |
45 | TNK2 | 0.87734830 |
46 | MAP3K3 | 0.81818169 |
47 | CDK6 | 0.80543794 |
48 | MAPK12 | 0.80211039 |
49 | MET | 0.79680022 |
50 | MAP3K11 | 0.79470593 |
51 | EPHB1 | 0.78594496 |
52 | TIE1 | 0.77591675 |
53 | SMG1 | 0.77498422 |
54 | PRKG2 | 0.77021564 |
55 | DYRK1B | 0.75808449 |
56 | PRKACG | 0.74962832 |
57 | MAP2K6 | 0.74241905 |
58 | EPHA3 | 0.72615001 |
59 | CAMK2G | 0.71246471 |
60 | CSK | 0.69385923 |
61 | MYLK | 0.68556582 |
62 | PRKACA | 0.66989490 |
63 | PRKG1 | 0.65574880 |
64 | GSK3A | 0.65323180 |
65 | PRKAA1 | 0.64566003 |
66 | CDC42BPA | 0.64438545 |
67 | CAMK1D | 0.63738506 |
68 | MAPKAPK3 | 0.62559481 |
69 | IRAK3 | 0.61417065 |
70 | PIM2 | 0.60976019 |
71 | PDGFRA | 0.59145124 |
72 | CSF1R | 0.58574194 |
73 | SGK3 | 0.58190299 |
74 | MAPK7 | 0.56655119 |
75 | IKBKE | 0.56071735 |
76 | RIPK1 | 0.55206066 |
77 | TGFBR2 | 0.54122049 |
78 | PRKCQ | 0.53828642 |
79 | PTK2 | 0.52579034 |
80 | FGFR3 | 0.52076609 |
81 | CSNK1G1 | 0.51951720 |
82 | TAOK1 | 0.51083204 |
83 | SIK3 | 0.51049980 |
84 | MAP3K13 | 0.49946480 |
85 | PDPK1 | 0.49606436 |
86 | CSNK1D | 0.48641669 |
87 | TAOK2 | 0.48313674 |
88 | SRC | 0.48171343 |
89 | DAPK3 | 0.46815769 |
90 | FES | 0.44624556 |
91 | GRK1 | 0.44402927 |
92 | RET | 0.43859415 |
93 | NTRK1 | 0.43632204 |
94 | IGF1R | 0.43159094 |
95 | ARAF | 0.42573253 |
96 | CDK4 | 0.42460870 |
97 | SIK2 | 0.41995167 |
98 | MAP3K5 | 0.41722757 |
99 | SGK2 | 0.41438742 |
100 | EPHA4 | 0.41267622 |
101 | BLK | 0.41212872 |
102 | MAPK3 | 0.41044377 |
103 | ICK | 0.40983200 |
104 | STK38 | 0.40861263 |
105 | MAP2K1 | 0.40173187 |
106 | PRKCG | 0.39619470 |
107 | AKT2 | 0.39041098 |
108 | MAP3K6 | 0.38859286 |
109 | PRKD2 | 0.38703515 |
110 | PRKCB | 0.38248060 |
111 | RPS6KC1 | 0.37445119 |
112 | RPS6KL1 | 0.37445119 |
113 | MAP3K12 | 0.37275367 |
114 | CAMKK1 | 0.34386484 |
115 | EPHB2 | 0.34212244 |
116 | FER | 0.34180114 |
117 | MUSK | 0.33248832 |
118 | PKN1 | 0.33181197 |
119 | CSNK1G3 | 0.32530046 |
120 | MTOR | 0.32402184 |
121 | CSNK1G2 | 0.32269802 |
122 | PDK3 | 0.32051641 |
123 | PDK4 | 0.32051641 |
124 | CAMK4 | 0.31733011 |
125 | EGFR | 0.31652129 |
126 | PDK1 | 0.31628028 |
127 | PBK | 0.28557323 |
128 | SGK494 | 0.28458673 |
129 | SGK223 | 0.28458673 |
130 | MAP3K1 | 0.25635188 |
131 | IRAK1 | 0.25307712 |
132 | PRKCA | 0.25131356 |
133 | IRAK2 | 0.23250445 |
134 | CSNK1A1L | 0.21182647 |
135 | MAP2K2 | 0.19960965 |
136 | ABL1 | 0.19334145 |
137 | LATS2 | 0.18656756 |
138 | KIT | 0.18186011 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 4.56995368 |
2 | Nitrogen metabolism_Homo sapiens_hsa00910 | 3.47093482 |
3 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 3.37735459 |
4 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 3.35418012 |
5 | Arginine biosynthesis_Homo sapiens_hsa00220 | 3.05087021 |
6 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 2.70548168 |
7 | Tryptophan metabolism_Homo sapiens_hsa00380 | 2.70330121 |
8 | * Complement and coagulation cascades_Homo sapiens_hsa04610 | 2.67960243 |
9 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 2.64587779 |
10 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 2.54771030 |
11 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.49193735 |
12 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.39820067 |
13 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 2.26611675 |
14 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 2.15982743 |
15 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.15273445 |
16 | Peroxisome_Homo sapiens_hsa04146 | 2.10392067 |
17 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.97844720 |
18 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.95587217 |
19 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.95143819 |
20 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.94048873 |
21 | Histidine metabolism_Homo sapiens_hsa00340 | 1.91598716 |
22 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.86599118 |
23 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.80685949 |
24 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.80546285 |
25 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.77651585 |
26 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.72955442 |
27 | Retinol metabolism_Homo sapiens_hsa00830 | 1.72834596 |
28 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.72723609 |
29 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.70762767 |
30 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.67719554 |
31 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.61404223 |
32 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.59622111 |
33 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.56759135 |
34 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.52869368 |
35 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.50654294 |
36 | Bile secretion_Homo sapiens_hsa04976 | 1.48801782 |
37 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.45703290 |
38 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.38428479 |
39 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.37830160 |
40 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.34789160 |
41 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.32344562 |
42 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.28148202 |
43 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.24908391 |
44 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.20369414 |
45 | ABC transporters_Homo sapiens_hsa02010 | 1.18790587 |
46 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.16931616 |
47 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.16542704 |
48 | Carbon metabolism_Homo sapiens_hsa01200 | 1.13400578 |
49 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.04741595 |
50 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.03226245 |
51 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.01017488 |
52 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.98508985 |
53 | Sulfur relay system_Homo sapiens_hsa04122 | 0.97706219 |
54 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.96453296 |
55 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.95648338 |
56 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.87922600 |
57 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.83397639 |
58 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.82294912 |
59 | Lysine degradation_Homo sapiens_hsa00310 | 0.80532004 |
60 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.77159831 |
61 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.71467412 |
62 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.67346279 |
63 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.66108427 |
64 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.59133296 |
65 | Other glycan degradation_Homo sapiens_hsa00511 | 0.57189503 |
66 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.52755413 |
67 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.48466490 |
68 | Metabolic pathways_Homo sapiens_hsa01100 | 0.46915391 |
69 | Pertussis_Homo sapiens_hsa05133 | 0.46255472 |
70 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.43381567 |
71 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.26748047 |
72 | Galactose metabolism_Homo sapiens_hsa00052 | 0.25868678 |
73 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.24431694 |
74 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.24346176 |
75 | Insulin resistance_Homo sapiens_hsa04931 | 0.22316793 |
76 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.21004563 |
77 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.18901176 |
78 | * Prion diseases_Homo sapiens_hsa05020 | 0.16299575 |
79 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.16131258 |
80 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.09687569 |
81 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.01374190 |
82 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | -0.2548857 |
83 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | -0.2448459 |
84 | Ether lipid metabolism_Homo sapiens_hsa00565 | -0.2402785 |
85 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | -0.2379273 |
86 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | -0.2246196 |
87 | * Systemic lupus erythematosus_Homo sapiens_hsa05322 | -0.2242369 |
88 | Renin-angiotensin system_Homo sapiens_hsa04614 | -0.1949754 |
89 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | -0.1920424 |
90 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | -0.1892993 |
91 | Lysosome_Homo sapiens_hsa04142 | -0.1890397 |
92 | Hepatitis C_Homo sapiens_hsa05160 | -0.1852333 |
93 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | -0.1740576 |
94 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | -0.1544372 |
95 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | -0.1532784 |
96 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | -0.1518805 |
97 | African trypanosomiasis_Homo sapiens_hsa05143 | -0.1488063 |
98 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | -0.1312974 |
99 | Regulation of autophagy_Homo sapiens_hsa04140 | -0.1248918 |
100 | Serotonergic synapse_Homo sapiens_hsa04726 | -0.1204692 |
101 | Insulin signaling pathway_Homo sapiens_hsa04910 | -0.1056443 |
102 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | -0.0993947 |
103 | * Amoebiasis_Homo sapiens_hsa05146 | -0.0916552 |
104 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | -0.0789831 |
105 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | -0.0728091 |
106 | Sphingolipid metabolism_Homo sapiens_hsa00600 | -0.0594242 |
107 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | -0.0303093 |
108 | Mineral absorption_Homo sapiens_hsa04978 | -0.0016946 |