

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | synaptic vesicle maturation (GO:0016188) | 7.75509367 |
| 2 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 7.74256974 |
| 3 | glutamate secretion (GO:0014047) | 6.94889274 |
| 4 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 6.34980031 |
| 5 | synaptic vesicle exocytosis (GO:0016079) | 6.31442852 |
| 6 | regulation of synaptic vesicle exocytosis (GO:2000300) | 6.16110074 |
| 7 | cellular potassium ion homeostasis (GO:0030007) | 5.77805976 |
| 8 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 5.77154825 |
| 9 | regulation of synaptic vesicle transport (GO:1902803) | 5.47695889 |
| 10 | L-amino acid import (GO:0043092) | 5.44241761 |
| 11 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 5.38499446 |
| 12 | sodium ion export (GO:0071436) | 5.35463526 |
| 13 | axon ensheathment in central nervous system (GO:0032291) | 5.26380209 |
| 14 | central nervous system myelination (GO:0022010) | 5.26380209 |
| 15 | neurotransmitter secretion (GO:0007269) | 5.10914555 |
| 16 | locomotory exploration behavior (GO:0035641) | 5.09696292 |
| 17 | regulation of neuronal synaptic plasticity (GO:0048168) | 4.91933688 |
| 18 | vocalization behavior (GO:0071625) | 4.91344887 |
| 19 | amino acid import (GO:0043090) | 4.88579221 |
| 20 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 4.73917766 |
| 21 | neuronal ion channel clustering (GO:0045161) | 4.73306818 |
| 22 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 4.66418251 |
| 23 | dendritic spine morphogenesis (GO:0060997) | 4.60835152 |
| 24 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 4.54785405 |
| 25 | neuronal action potential propagation (GO:0019227) | 4.52830052 |
| 26 | protein localization to synapse (GO:0035418) | 4.50253641 |
| 27 | exploration behavior (GO:0035640) | 4.49289084 |
| 28 | postsynaptic membrane organization (GO:0001941) | 4.37957277 |
| 29 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 4.32196073 |
| 30 | neurotransmitter transport (GO:0006836) | 4.30494264 |
| 31 | activation of protein kinase A activity (GO:0034199) | 4.28528181 |
| 32 | regulation of glutamate receptor signaling pathway (GO:1900449) | 4.26703873 |
| 33 | cerebellar granule cell differentiation (GO:0021707) | 4.23854229 |
| 34 | potassium ion homeostasis (GO:0055075) | 4.22981360 |
| 35 | positive regulation of membrane potential (GO:0045838) | 4.17843774 |
| 36 | potassium ion import (GO:0010107) | 4.13433222 |
| 37 | synaptic transmission, glutamatergic (GO:0035249) | 4.11302663 |
| 38 | positive regulation of dendritic spine development (GO:0060999) | 4.10733649 |
| 39 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 4.08553683 |
| 40 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 4.06451886 |
| 41 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 4.04727472 |
| 42 | neuron cell-cell adhesion (GO:0007158) | 3.99127477 |
| 43 | positive regulation of synapse maturation (GO:0090129) | 3.93606034 |
| 44 | neuron-neuron synaptic transmission (GO:0007270) | 3.93559175 |
| 45 | regulation of synapse structural plasticity (GO:0051823) | 3.91362002 |
| 46 | regulation of neurotransmitter secretion (GO:0046928) | 3.91065519 |
| 47 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 3.88643600 |
| 48 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.84635006 |
| 49 | regulation of synaptic plasticity (GO:0048167) | 3.81100358 |
| 50 | regulation of neurotransmitter levels (GO:0001505) | 3.79109101 |
| 51 | regulation of voltage-gated calcium channel activity (GO:1901385) | 3.77775866 |
| 52 | neuromuscular process controlling balance (GO:0050885) | 3.74223367 |
| 53 | acidic amino acid transport (GO:0015800) | 3.72228207 |
| 54 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 3.71012771 |
| 55 | regulation of neurotransmitter transport (GO:0051588) | 3.64842635 |
| 56 | neurotransmitter uptake (GO:0001504) | 3.62582697 |
| 57 | negative regulation of dendrite morphogenesis (GO:0050774) | 3.60365568 |
| 58 | glutamate receptor signaling pathway (GO:0007215) | 3.58331366 |
| 59 | cell communication by electrical coupling (GO:0010644) | 3.57684281 |
| 60 | long-term memory (GO:0007616) | 3.57480431 |
| 61 | synaptic vesicle endocytosis (GO:0048488) | 3.54840658 |
| 62 | gamma-aminobutyric acid transport (GO:0015812) | 3.54224214 |
| 63 | cellular sodium ion homeostasis (GO:0006883) | 3.53825282 |
| 64 | dendritic spine organization (GO:0097061) | 3.52418463 |
| 65 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 3.47966850 |
| 66 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.46514253 |
| 67 | presynaptic membrane organization (GO:0097090) | 3.46019777 |
| 68 | regulation of dendritic spine development (GO:0060998) | 3.44172360 |
| 69 | regulation of postsynaptic membrane potential (GO:0060078) | 3.42425831 |
| 70 | positive regulation of neurotransmitter secretion (GO:0001956) | 3.42168148 |
| 71 | regulation of dendritic spine morphogenesis (GO:0061001) | 3.35560293 |
| 72 | neuromuscular synaptic transmission (GO:0007274) | 3.34814149 |
| 73 | positive regulation of neurotransmitter transport (GO:0051590) | 3.33780534 |
| 74 | L-glutamate transport (GO:0015813) | 3.32547295 |
| 75 | presynaptic membrane assembly (GO:0097105) | 3.32030653 |
| 76 | layer formation in cerebral cortex (GO:0021819) | 3.31088892 |
| 77 | regulation of ARF protein signal transduction (GO:0032012) | 3.29596165 |
| 78 | regulation of vesicle fusion (GO:0031338) | 3.23118112 |
| 79 | neuromuscular process controlling posture (GO:0050884) | 3.21738796 |
| 80 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 3.21301633 |
| 81 | long-term synaptic potentiation (GO:0060291) | 3.18784939 |
| 82 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 3.18626692 |
| 83 | synaptic transmission (GO:0007268) | 3.18455330 |
| 84 | cerebellar Purkinje cell differentiation (GO:0021702) | 3.16404024 |
| 85 | regulation of synaptic transmission (GO:0050804) | 3.16299242 |
| 86 | response to auditory stimulus (GO:0010996) | 3.16261370 |
| 87 | chemosensory behavior (GO:0007635) | 3.15462205 |
| 88 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 3.15361221 |
| 89 | auditory behavior (GO:0031223) | 3.14580913 |
| 90 | regulation of synapse maturation (GO:0090128) | 3.11006861 |
| 91 | membrane depolarization during action potential (GO:0086010) | 3.09835668 |
| 92 | membrane depolarization (GO:0051899) | 3.08932379 |
| 93 | transmission of nerve impulse (GO:0019226) | 3.06458427 |
| 94 | regulation of cell communication by electrical coupling (GO:0010649) | 3.03216413 |
| 95 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 3.00458880 |
| 96 | proline transport (GO:0015824) | 2.99306428 |
| 97 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 2.97227244 |
| 98 | detection of calcium ion (GO:0005513) | 2.95274463 |
| 99 | neuromuscular process (GO:0050905) | 2.94322391 |
| 100 | potassium ion transmembrane transport (GO:0071805) | 2.92118898 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.50412139 |
| 2 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 3.16478556 |
| 3 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 3.15060967 |
| 4 | REST_21632747_ChIP-Seq_MESCs_Mouse | 3.13484813 |
| 5 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 3.12677602 |
| 6 | DROSHA_22980978_ChIP-Seq_HELA_Human | 3.03242077 |
| 7 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.95129627 |
| 8 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.88102872 |
| 9 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.75950492 |
| 10 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.74493619 |
| 11 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.72729986 |
| 12 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.62079386 |
| 13 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.62079386 |
| 14 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.59566383 |
| 15 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 2.57325774 |
| 16 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.55832091 |
| 17 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.49896732 |
| 18 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.48313508 |
| 19 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.47713541 |
| 20 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.41816978 |
| 21 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.41582942 |
| 22 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 2.39864840 |
| 23 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.38557646 |
| 24 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.35387568 |
| 25 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.30917604 |
| 26 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.18670559 |
| 27 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.17834934 |
| 28 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.05451543 |
| 29 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.97755995 |
| 30 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.75020138 |
| 31 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.68719194 |
| 32 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.64959177 |
| 33 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.63699426 |
| 34 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.48009242 |
| 35 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.44752157 |
| 36 | KDM2B_26808549_Chip-Seq_K562_Human | 1.42389102 |
| 37 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.40777046 |
| 38 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.40277782 |
| 39 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.36516870 |
| 40 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.24878418 |
| 41 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.24454417 |
| 42 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.21612185 |
| 43 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.20913470 |
| 44 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.19076753 |
| 45 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.17580691 |
| 46 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.16729249 |
| 47 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.15597838 |
| 48 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.14721057 |
| 49 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.13957584 |
| 50 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.13175638 |
| 51 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 1.12006760 |
| 52 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.09714798 |
| 53 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.07082233 |
| 54 | AR_19668381_ChIP-Seq_PC3_Human | 1.06701672 |
| 55 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.06687229 |
| 56 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.05293352 |
| 57 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.04411098 |
| 58 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.03611440 |
| 59 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.01514506 |
| 60 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.00827241 |
| 61 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.99740805 |
| 62 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.99625114 |
| 63 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.98482641 |
| 64 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.98420227 |
| 65 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.97876082 |
| 66 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 0.96890878 |
| 67 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.96469795 |
| 68 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.96276271 |
| 69 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.96249643 |
| 70 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.94973045 |
| 71 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.94811140 |
| 72 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.94102970 |
| 73 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.93934034 |
| 74 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.92564486 |
| 75 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.92296592 |
| 76 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.91932034 |
| 77 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.91325325 |
| 78 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 0.90398509 |
| 79 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.89136079 |
| 80 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.86645305 |
| 81 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.86645305 |
| 82 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.86613777 |
| 83 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.86154452 |
| 84 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.85034826 |
| 85 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.83877975 |
| 86 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.81741525 |
| 87 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.81627152 |
| 88 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.81413413 |
| 89 | DPY_21335234_ChIP-Seq_ESCs_Mouse | 0.80659312 |
| 90 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.80377753 |
| 91 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.79177460 |
| 92 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.76698951 |
| 93 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.76287811 |
| 94 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.75811488 |
| 95 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.75554149 |
| 96 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.75201756 |
| 97 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.75064711 |
| 98 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.74847629 |
| 99 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.74666380 |
| 100 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.74239201 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0004859_abnormal_synaptic_plasticity | 6.42176451 |
| 2 | MP0003880_abnormal_central_pattern | 5.71035097 |
| 3 | MP0005423_abnormal_somatic_nervous | 4.55163836 |
| 4 | MP0004270_analgesia | 4.43262062 |
| 5 | MP0003635_abnormal_synaptic_transmissio | 3.98473383 |
| 6 | MP0002064_seizures | 3.68853238 |
| 7 | MP0009745_abnormal_behavioral_response | 3.26006798 |
| 8 | MP0002063_abnormal_learning/memory/cond | 3.20970665 |
| 9 | MP0001486_abnormal_startle_reflex | 3.04219440 |
| 10 | MP0002272_abnormal_nervous_system | 3.01645742 |
| 11 | MP0002734_abnormal_mechanical_nocicepti | 2.81948324 |
| 12 | MP0001968_abnormal_touch/_nociception | 2.77585032 |
| 13 | MP0002572_abnormal_emotion/affect_behav | 2.76889685 |
| 14 | MP0009046_muscle_twitch | 2.75989958 |
| 15 | MP0003329_amyloid_beta_deposits | 2.64401724 |
| 16 | MP0008569_lethality_at_weaning | 2.46468587 |
| 17 | MP0001501_abnormal_sleep_pattern | 2.25657018 |
| 18 | MP0003879_abnormal_hair_cell | 2.22041026 |
| 19 | MP0003690_abnormal_glial_cell | 2.19467155 |
| 20 | MP0002735_abnormal_chemical_nociception | 2.18109804 |
| 21 | MP0002736_abnormal_nociception_after | 2.03945898 |
| 22 | MP0000920_abnormal_myelination | 2.02663083 |
| 23 | MP0001970_abnormal_pain_threshold | 1.93505080 |
| 24 | MP0004885_abnormal_endolymph | 1.87750449 |
| 25 | MP0002733_abnormal_thermal_nociception | 1.77838218 |
| 26 | MP0005646_abnormal_pituitary_gland | 1.76003552 |
| 27 | MP0003633_abnormal_nervous_system | 1.75320963 |
| 28 | MP0002067_abnormal_sensory_capabilities | 1.71234642 |
| 29 | MP0009780_abnormal_chondrocyte_physiolo | 1.69946259 |
| 30 | MP0006276_abnormal_autonomic_nervous | 1.69033652 |
| 31 | MP0000778_abnormal_nervous_system | 1.67558622 |
| 32 | MP0004811_abnormal_neuron_physiology | 1.66519562 |
| 33 | MP0002557_abnormal_social/conspecific_i | 1.61535951 |
| 34 | MP0001440_abnormal_grooming_behavior | 1.57421179 |
| 35 | MP0001502_abnormal_circadian_rhythm | 1.54717738 |
| 36 | MP0003787_abnormal_imprinting | 1.52892933 |
| 37 | MP0001905_abnormal_dopamine_level | 1.51569232 |
| 38 | MP0002066_abnormal_motor_capabilities/c | 1.50667624 |
| 39 | MP0002882_abnormal_neuron_morphology | 1.49259624 |
| 40 | MP0003631_nervous_system_phenotype | 1.48286230 |
| 41 | MP0001984_abnormal_olfaction | 1.47774230 |
| 42 | MP0000955_abnormal_spinal_cord | 1.45944238 |
| 43 | MP0005386_behavior/neurological_phenoty | 1.36384757 |
| 44 | MP0004924_abnormal_behavior | 1.36384757 |
| 45 | MP0003634_abnormal_glial_cell | 1.35062740 |
| 46 | MP0002822_catalepsy | 1.29013994 |
| 47 | MP0000604_amyloidosis | 1.27958953 |
| 48 | MP0001177_atelectasis | 1.27691398 |
| 49 | MP0001529_abnormal_vocalization | 1.19399980 |
| 50 | MP0002229_neurodegeneration | 1.18047658 |
| 51 | MP0003632_abnormal_nervous_system | 1.17420263 |
| 52 | MP0004742_abnormal_vestibular_system | 1.13657966 |
| 53 | MP0004130_abnormal_muscle_cell | 1.12298162 |
| 54 | MP0002184_abnormal_innervation | 1.11898599 |
| 55 | MP0002152_abnormal_brain_morphology | 1.07963371 |
| 56 | MP0005551_abnormal_eye_electrophysiolog | 1.02870460 |
| 57 | MP0001963_abnormal_hearing_physiology | 1.02571555 |
| 58 | MP0005645_abnormal_hypothalamus_physiol | 1.01745966 |
| 59 | MP0003122_maternal_imprinting | 0.99433315 |
| 60 | MP0003123_paternal_imprinting | 0.98613919 |
| 61 | MP0001485_abnormal_pinna_reflex | 0.97465853 |
| 62 | MP0003075_altered_response_to | 0.96874619 |
| 63 | MP0002638_abnormal_pupillary_reflex | 0.96309262 |
| 64 | MP0001346_abnormal_lacrimal_gland | 0.96123288 |
| 65 | MP0005167_abnormal_blood-brain_barrier | 0.94132614 |
| 66 | MP0002909_abnormal_adrenal_gland | 0.83296111 |
| 67 | MP0001986_abnormal_taste_sensitivity | 0.80955714 |
| 68 | MP0008874_decreased_physiological_sensi | 0.80877401 |
| 69 | MP0004142_abnormal_muscle_tone | 0.80443381 |
| 70 | MP0010386_abnormal_urinary_bladder | 0.78858165 |
| 71 | MP0008961_abnormal_basal_metabolism | 0.78245187 |
| 72 | MP0005084_abnormal_gallbladder_morpholo | 0.73697928 |
| 73 | MP0004147_increased_porphyrin_level | 0.71938113 |
| 74 | MP0002069_abnormal_eating/drinking_beha | 0.71705347 |
| 75 | MP0002752_abnormal_somatic_nervous | 0.71486497 |
| 76 | MP0005535_abnormal_body_temperature | 0.64896016 |
| 77 | MP0005623_abnormal_meninges_morphology | 0.59631431 |
| 78 | MP0000026_abnormal_inner_ear | 0.58376545 |
| 79 | MP0000569_abnormal_digit_pigmentation | 0.54835830 |
| 80 | MP0008872_abnormal_physiological_respon | 0.54671342 |
| 81 | MP0002653_abnormal_ependyma_morphology | 0.54365555 |
| 82 | MP0010769_abnormal_survival | 0.53679994 |
| 83 | MP0000579_abnormal_nail_morphology | 0.53674845 |
| 84 | MP0005253_abnormal_eye_physiology | 0.53147152 |
| 85 | MP0001943_abnormal_respiration | 0.50761765 |
| 86 | MP0003137_abnormal_impulse_conducting | 0.50469356 |
| 87 | MP0010768_mortality/aging | 0.49846548 |
| 88 | MP0001299_abnormal_eye_distance/ | 0.49777968 |
| 89 | MP0010770_preweaning_lethality | 0.49700880 |
| 90 | MP0002082_postnatal_lethality | 0.49700880 |
| 91 | MP0003956_abnormal_body_size | 0.48899775 |
| 92 | MP0001348_abnormal_lacrimal_gland | 0.47315956 |
| 93 | MP0003121_genomic_imprinting | 0.45931272 |
| 94 | MP0003861_abnormal_nervous_system | 0.45774446 |
| 95 | MP0000631_abnormal_neuroendocrine_gland | 0.44670730 |
| 96 | MP0003172_abnormal_lysosome_physiology | 0.44567132 |
| 97 | MP0005171_absent_coat_pigmentation | 0.44536594 |
| 98 | MP0000566_synostosis | 0.44228269 |
| 99 | MP0005166_decreased_susceptibility_to | 0.42826866 |
| 100 | MP0000639_abnormal_adrenal_gland | 0.40242362 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Myokymia (HP:0002411) | 8.00565465 |
| 2 | Focal motor seizures (HP:0011153) | 7.48737422 |
| 3 | Focal seizures (HP:0007359) | 6.11424570 |
| 4 | Febrile seizures (HP:0002373) | 5.41738588 |
| 5 | Action tremor (HP:0002345) | 5.37258230 |
| 6 | Atonic seizures (HP:0010819) | 5.21323706 |
| 7 | Diplopia (HP:0000651) | 4.98158173 |
| 8 | Abnormality of binocular vision (HP:0011514) | 4.98158173 |
| 9 | Epileptic encephalopathy (HP:0200134) | 4.97676807 |
| 10 | Supranuclear gaze palsy (HP:0000605) | 4.79649495 |
| 11 | Ankle clonus (HP:0011448) | 4.56328377 |
| 12 | Neurofibrillary tangles (HP:0002185) | 4.46919780 |
| 13 | Generalized tonic-clonic seizures (HP:0002069) | 4.10878304 |
| 14 | Spastic gait (HP:0002064) | 3.89122093 |
| 15 | Abnormal eating behavior (HP:0100738) | 3.81213763 |
| 16 | Absence seizures (HP:0002121) | 3.74964797 |
| 17 | Papilledema (HP:0001085) | 3.73325809 |
| 18 | Visual hallucinations (HP:0002367) | 3.64062931 |
| 19 | Torticollis (HP:0000473) | 3.56043262 |
| 20 | Postural instability (HP:0002172) | 3.53158309 |
| 21 | Truncal ataxia (HP:0002078) | 3.53093367 |
| 22 | Dialeptic seizures (HP:0011146) | 3.52621291 |
| 23 | Cerebral inclusion bodies (HP:0100314) | 3.51257433 |
| 24 | Progressive cerebellar ataxia (HP:0002073) | 3.37943831 |
| 25 | Dysmetria (HP:0001310) | 3.37437810 |
| 26 | Hemiplegia (HP:0002301) | 3.36437876 |
| 27 | Intention tremor (HP:0002080) | 3.34829310 |
| 28 | Urinary bladder sphincter dysfunction (HP:0002839) | 3.29666364 |
| 29 | Cerebral hypomyelination (HP:0006808) | 3.27475485 |
| 30 | Limb dystonia (HP:0002451) | 3.25956330 |
| 31 | Mutism (HP:0002300) | 3.19218754 |
| 32 | Peripheral hypomyelination (HP:0007182) | 3.16993181 |
| 33 | Obstructive sleep apnea (HP:0002870) | 3.11828906 |
| 34 | Impaired vibration sensation in the lower limbs (HP:0002166) | 3.11333009 |
| 35 | Annular pancreas (HP:0001734) | 3.04701059 |
| 36 | Urinary urgency (HP:0000012) | 3.03127230 |
| 37 | Abnormality of the corticospinal tract (HP:0002492) | 3.02643943 |
| 38 | Focal dystonia (HP:0004373) | 2.93823912 |
| 39 | Depression (HP:0000716) | 2.85659078 |
| 40 | Tetraplegia (HP:0002445) | 2.85331628 |
| 41 | Lower limb muscle weakness (HP:0007340) | 2.85135925 |
| 42 | Scanning speech (HP:0002168) | 2.85082179 |
| 43 | Akinesia (HP:0002304) | 2.83196877 |
| 44 | Delusions (HP:0000746) | 2.80454480 |
| 45 | Neuronal loss in central nervous system (HP:0002529) | 2.79740104 |
| 46 | Status epilepticus (HP:0002133) | 2.78659642 |
| 47 | Craniofacial dystonia (HP:0012179) | 2.73952439 |
| 48 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.73180697 |
| 49 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.73180697 |
| 50 | Hemiparesis (HP:0001269) | 2.71473012 |
| 51 | Increased circulating renin level (HP:0000848) | 2.70118763 |
| 52 | Bradykinesia (HP:0002067) | 2.68565608 |
| 53 | Dysdiadochokinesis (HP:0002075) | 2.67439647 |
| 54 | Anxiety (HP:0000739) | 2.67066375 |
| 55 | Epileptiform EEG discharges (HP:0011182) | 2.66727032 |
| 56 | Split foot (HP:0001839) | 2.56685899 |
| 57 | Clonus (HP:0002169) | 2.56008544 |
| 58 | Megalencephaly (HP:0001355) | 2.53626574 |
| 59 | Amblyopia (HP:0000646) | 2.49877865 |
| 60 | Apathy (HP:0000741) | 2.48704720 |
| 61 | Insomnia (HP:0100785) | 2.44650342 |
| 62 | Poor eye contact (HP:0000817) | 2.44393448 |
| 63 | Spastic tetraparesis (HP:0001285) | 2.41822123 |
| 64 | Rigidity (HP:0002063) | 2.33980779 |
| 65 | Sleep apnea (HP:0010535) | 2.33171916 |
| 66 | EEG with generalized epileptiform discharges (HP:0011198) | 2.28348192 |
| 67 | Drooling (HP:0002307) | 2.21957625 |
| 68 | Polyphagia (HP:0002591) | 2.21883319 |
| 69 | Diminished motivation (HP:0000745) | 2.21716554 |
| 70 | Choreoathetosis (HP:0001266) | 2.15691292 |
| 71 | Morphological abnormality of the pyramidal tract (HP:0002062) | 2.14563440 |
| 72 | Impaired vibratory sensation (HP:0002495) | 2.14370637 |
| 73 | Rapidly progressive (HP:0003678) | 2.13512148 |
| 74 | Abnormality of the lower motor neuron (HP:0002366) | 2.11515219 |
| 75 | Hypsarrhythmia (HP:0002521) | 2.10772498 |
| 76 | Excessive salivation (HP:0003781) | 2.06439907 |
| 77 | Impaired social interactions (HP:0000735) | 2.03918578 |
| 78 | Abnormal social behavior (HP:0012433) | 2.03918578 |
| 79 | Incomplete penetrance (HP:0003829) | 2.02287875 |
| 80 | Impaired smooth pursuit (HP:0007772) | 2.01804671 |
| 81 | CNS hypomyelination (HP:0003429) | 1.99849815 |
| 82 | Stereotypic behavior (HP:0000733) | 1.96338913 |
| 83 | Bundle branch block (HP:0011710) | 1.95708446 |
| 84 | Broad-based gait (HP:0002136) | 1.94272418 |
| 85 | Aplasia involving bones of the upper limbs (HP:0009823) | 1.86594238 |
| 86 | Aplasia of the phalanges of the hand (HP:0009802) | 1.86594238 |
| 87 | Aplasia involving bones of the extremities (HP:0009825) | 1.86594238 |
| 88 | Overgrowth (HP:0001548) | 1.84670099 |
| 89 | Hyperventilation (HP:0002883) | 1.82856944 |
| 90 | Abnormality of ocular smooth pursuit (HP:0000617) | 1.82411146 |
| 91 | Fetal akinesia sequence (HP:0001989) | 1.81094831 |
| 92 | Gaze-evoked nystagmus (HP:0000640) | 1.78568137 |
| 93 | Ventricular fibrillation (HP:0001663) | 1.78397700 |
| 94 | Amyotrophic lateral sclerosis (HP:0007354) | 1.76830349 |
| 95 | Memory impairment (HP:0002354) | 1.74942784 |
| 96 | Dementia (HP:0000726) | 1.72737790 |
| 97 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 1.70594192 |
| 98 | Alacrima (HP:0000522) | 1.70131521 |
| 99 | Lower limb asymmetry (HP:0100559) | 1.69493020 |
| 100 | Heart block (HP:0012722) | 1.68510400 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EPHA4 | 5.71469896 |
| 2 | NTRK2 | 4.56012377 |
| 3 | NTRK3 | 4.14034327 |
| 4 | PAK6 | 3.91096650 |
| 5 | MARK1 | 3.65043809 |
| 6 | DAPK2 | 3.37227059 |
| 7 | UHMK1 | 2.84915949 |
| 8 | PRKD3 | 2.27429265 |
| 9 | MINK1 | 2.22280520 |
| 10 | CAMKK1 | 2.20494769 |
| 11 | MAP3K9 | 2.18936131 |
| 12 | NTRK1 | 2.17380690 |
| 13 | RIPK4 | 1.92081709 |
| 14 | CASK | 1.80415604 |
| 15 | PINK1 | 1.76792153 |
| 16 | PLK2 | 1.67546227 |
| 17 | LATS2 | 1.53996622 |
| 18 | CDK5 | 1.53932774 |
| 19 | ARAF | 1.52283717 |
| 20 | GRK5 | 1.50863588 |
| 21 | CAMK2B | 1.40288455 |
| 22 | TYRO3 | 1.37473118 |
| 23 | CAMK1 | 1.35525254 |
| 24 | PHKG2 | 1.33747487 |
| 25 | PHKG1 | 1.33747487 |
| 26 | CDK19 | 1.32604729 |
| 27 | KSR2 | 1.31516960 |
| 28 | MAPK13 | 1.27381546 |
| 29 | DAPK1 | 1.25318967 |
| 30 | SGK223 | 1.23546534 |
| 31 | SGK494 | 1.23546534 |
| 32 | PRKCG | 1.21460038 |
| 33 | NEK6 | 1.20345582 |
| 34 | BMPR2 | 1.14871284 |
| 35 | CDK15 | 1.09696991 |
| 36 | CAMK2A | 1.09106763 |
| 37 | PRKCH | 1.06685262 |
| 38 | RIPK1 | 1.06577981 |
| 39 | CDK18 | 1.05984794 |
| 40 | SIK2 | 1.05780462 |
| 41 | PKN1 | 1.05764951 |
| 42 | CAMK2G | 1.05011809 |
| 43 | PAK3 | 1.01528003 |
| 44 | CDK11A | 0.99806445 |
| 45 | PRPF4B | 0.99301388 |
| 46 | CDK14 | 0.98133517 |
| 47 | DYRK1A | 0.97815056 |
| 48 | CAMKK2 | 0.94274708 |
| 49 | SGK2 | 0.89697453 |
| 50 | MARK2 | 0.89481083 |
| 51 | MAPK12 | 0.84123560 |
| 52 | STK38 | 0.83933298 |
| 53 | ALK | 0.83435753 |
| 54 | ROCK2 | 0.78462742 |
| 55 | SGK1 | 0.77772944 |
| 56 | MAP3K13 | 0.74242950 |
| 57 | OXSR1 | 0.72791144 |
| 58 | STK11 | 0.72318858 |
| 59 | SGK3 | 0.71955272 |
| 60 | CAMK2D | 0.68621601 |
| 61 | MAPK10 | 0.67940471 |
| 62 | CAMK4 | 0.66447683 |
| 63 | MAP3K4 | 0.65551866 |
| 64 | TNK2 | 0.63397689 |
| 65 | BRSK1 | 0.63220528 |
| 66 | FES | 0.62943378 |
| 67 | LIMK1 | 0.61455858 |
| 68 | PDK1 | 0.60358349 |
| 69 | DAPK3 | 0.59852165 |
| 70 | KSR1 | 0.59612464 |
| 71 | RPS6KA3 | 0.58407811 |
| 72 | FGFR2 | 0.53745796 |
| 73 | MAP2K7 | 0.52295490 |
| 74 | PDPK1 | 0.51477932 |
| 75 | ROCK1 | 0.49499710 |
| 76 | MAP2K4 | 0.48999942 |
| 77 | FYN | 0.48142585 |
| 78 | RAF1 | 0.47075610 |
| 79 | PRKCZ | 0.47054233 |
| 80 | LMTK2 | 0.45430965 |
| 81 | CCNB1 | 0.43643026 |
| 82 | MAP3K11 | 0.43365628 |
| 83 | CSNK1G2 | 0.41173677 |
| 84 | BRAF | 0.39534685 |
| 85 | PRKCA | 0.37018058 |
| 86 | RET | 0.36556830 |
| 87 | ERBB2 | 0.36153037 |
| 88 | PRKG2 | 0.33310495 |
| 89 | SRC | 0.31620263 |
| 90 | TESK1 | 0.31035914 |
| 91 | PRKG1 | 0.29916863 |
| 92 | PRKACA | 0.29601076 |
| 93 | WNK1 | 0.29592243 |
| 94 | MAP3K1 | 0.29132835 |
| 95 | MAP3K2 | 0.28970115 |
| 96 | PRKCB | 0.28535952 |
| 97 | CSNK1D | 0.27213620 |
| 98 | MAPKAPK5 | 0.26042681 |
| 99 | PRKCE | 0.25718388 |
| 100 | JAK2 | 0.25413146 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 3.92424815 |
| 2 | Nicotine addiction_Homo sapiens_hsa05033 | 3.87226881 |
| 3 | GABAergic synapse_Homo sapiens_hsa04727 | 2.89718511 |
| 4 | Circadian entrainment_Homo sapiens_hsa04713 | 2.84749093 |
| 5 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.73908171 |
| 6 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.70916085 |
| 7 | Morphine addiction_Homo sapiens_hsa05032 | 2.68838308 |
| 8 | Long-term potentiation_Homo sapiens_hsa04720 | 2.65550007 |
| 9 | Insulin secretion_Homo sapiens_hsa04911 | 2.60371870 |
| 10 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.56036645 |
| 11 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 2.44865746 |
| 12 | Gastric acid secretion_Homo sapiens_hsa04971 | 2.35726713 |
| 13 | Cocaine addiction_Homo sapiens_hsa05030 | 2.08592094 |
| 14 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 2.06986248 |
| 15 | Dopaminergic synapse_Homo sapiens_hsa04728 | 2.03834894 |
| 16 | Salivary secretion_Homo sapiens_hsa04970 | 2.01747475 |
| 17 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 2.01611930 |
| 18 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.94287741 |
| 19 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.85341674 |
| 20 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.79844593 |
| 21 | Olfactory transduction_Homo sapiens_hsa04740 | 1.75798758 |
| 22 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.65396359 |
| 23 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.58274997 |
| 24 | Taste transduction_Homo sapiens_hsa04742 | 1.46734665 |
| 25 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.44162415 |
| 26 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.41229717 |
| 27 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.40210909 |
| 28 | Renin secretion_Homo sapiens_hsa04924 | 1.39859300 |
| 29 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.34376055 |
| 30 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.32022874 |
| 31 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.28107080 |
| 32 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 1.27871141 |
| 33 | Bile secretion_Homo sapiens_hsa04976 | 1.27030164 |
| 34 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.24549518 |
| 35 | Gap junction_Homo sapiens_hsa04540 | 1.23964055 |
| 36 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.23751255 |
| 37 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.13620735 |
| 38 | Melanogenesis_Homo sapiens_hsa04916 | 1.13346540 |
| 39 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 1.09671564 |
| 40 | Long-term depression_Homo sapiens_hsa04730 | 1.07896964 |
| 41 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.05009149 |
| 42 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.02813901 |
| 43 | Glioma_Homo sapiens_hsa05214 | 1.02258381 |
| 44 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.02226877 |
| 45 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.00594369 |
| 46 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.98623264 |
| 47 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.92837943 |
| 48 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.92005041 |
| 49 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.87257172 |
| 50 | Prion diseases_Homo sapiens_hsa05020 | 0.86270293 |
| 51 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.84354222 |
| 52 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.78409653 |
| 53 | Axon guidance_Homo sapiens_hsa04360 | 0.75607596 |
| 54 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.75543165 |
| 55 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.75453746 |
| 56 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.72056958 |
| 57 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.71437661 |
| 58 | Histidine metabolism_Homo sapiens_hsa00340 | 0.69672848 |
| 59 | Circadian rhythm_Homo sapiens_hsa04710 | 0.64295618 |
| 60 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.63821726 |
| 61 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.61223507 |
| 62 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.60346147 |
| 63 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.59797880 |
| 64 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.59598443 |
| 65 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.59333834 |
| 66 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.56355286 |
| 67 | Phototransduction_Homo sapiens_hsa04744 | 0.55407330 |
| 68 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.54583458 |
| 69 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.54019223 |
| 70 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.53656077 |
| 71 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.52988157 |
| 72 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.52660103 |
| 73 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.51926723 |
| 74 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.49502980 |
| 75 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.47351005 |
| 76 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.46619839 |
| 77 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.44845659 |
| 78 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.44616354 |
| 79 | Alcoholism_Homo sapiens_hsa05034 | 0.43114487 |
| 80 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.42442356 |
| 81 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.41443419 |
| 82 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.38711454 |
| 83 | Endocytosis_Homo sapiens_hsa04144 | 0.38110022 |
| 84 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.37151546 |
| 85 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.36837403 |
| 86 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.30454368 |
| 87 | Mineral absorption_Homo sapiens_hsa04978 | 0.26545574 |
| 88 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.24796684 |
| 89 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.22507138 |
| 90 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.21304249 |
| 91 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.21207658 |
| 92 | Alzheimers disease_Homo sapiens_hsa05010 | 0.19912919 |
| 93 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.18787407 |
| 94 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.18311815 |
| 95 | Tight junction_Homo sapiens_hsa04530 | 0.17503356 |
| 96 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.17420956 |
| 97 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.16847986 |
| 98 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.16406137 |
| 99 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.13664166 |
| 100 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.13458845 |

