

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | cilium or flagellum-dependent cell motility (GO:0001539) | 9.96972280 |
| 2 | epithelial cilium movement (GO:0003351) | 9.39182673 |
| 3 | motile cilium assembly (GO:0044458) | 8.92111205 |
| 4 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 8.41496259 |
| 5 | axoneme assembly (GO:0035082) | 6.37673739 |
| 6 | left/right pattern formation (GO:0060972) | 5.38458347 |
| 7 | intraciliary transport (GO:0042073) | 4.90416784 |
| 8 | regulation of cilium movement (GO:0003352) | 4.73043650 |
| 9 | primary alcohol catabolic process (GO:0034310) | 4.55770163 |
| 10 | centriole assembly (GO:0098534) | 4.29743534 |
| 11 | vitamin transmembrane transport (GO:0035461) | 4.27021840 |
| 12 | ventricular system development (GO:0021591) | 4.12724815 |
| 13 | left/right axis specification (GO:0070986) | 4.05976445 |
| 14 | cilium organization (GO:0044782) | 3.99422498 |
| 15 | establishment of integrated proviral latency (GO:0075713) | 3.96336481 |
| 16 | nucleoside diphosphate phosphorylation (GO:0006165) | 3.86332858 |
| 17 | cilium assembly (GO:0042384) | 3.86035744 |
| 18 | microtubule bundle formation (GO:0001578) | 3.70117570 |
| 19 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.60273807 |
| 20 | establishment of apical/basal cell polarity (GO:0035089) | 3.56279300 |
| 21 | chromatin remodeling at centromere (GO:0031055) | 3.55493384 |
| 22 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.49914456 |
| 23 | proteasome assembly (GO:0043248) | 3.49133939 |
| 24 | protein localization to cilium (GO:0061512) | 3.46002995 |
| 25 | CENP-A containing nucleosome assembly (GO:0034080) | 3.44971689 |
| 26 | intra-S DNA damage checkpoint (GO:0031573) | 3.42533515 |
| 27 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.38328673 |
| 28 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.38328673 |
| 29 | protein neddylation (GO:0045116) | 3.36722135 |
| 30 | cilium morphogenesis (GO:0060271) | 3.30351123 |
| 31 | aldehyde catabolic process (GO:0046185) | 3.30235342 |
| 32 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.29639663 |
| 33 | ethanol metabolic process (GO:0006067) | 3.29389226 |
| 34 | chaperone-mediated protein transport (GO:0072321) | 3.28673012 |
| 35 | glutathione derivative metabolic process (GO:1901685) | 3.20603012 |
| 36 | glutathione derivative biosynthetic process (GO:1901687) | 3.20603012 |
| 37 | DNA replication checkpoint (GO:0000076) | 3.20509261 |
| 38 | pyrimidine-containing compound transmembrane transport (GO:0072531) | 3.16496347 |
| 39 | regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | 3.15330791 |
| 40 | establishment of viral latency (GO:0019043) | 3.13637978 |
| 41 | establishment or maintenance of monopolar cell polarity (GO:0061339) | 3.13006777 |
| 42 | establishment of monopolar cell polarity (GO:0061162) | 3.13006777 |
| 43 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.12700966 |
| 44 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.12492059 |
| 45 | centriole replication (GO:0007099) | 3.09610901 |
| 46 | regulation of helicase activity (GO:0051095) | 3.07524583 |
| 47 | L-serine metabolic process (GO:0006563) | 3.06519956 |
| 48 | histone exchange (GO:0043486) | 3.03538250 |
| 49 | cellular component assembly involved in morphogenesis (GO:0010927) | 3.00735312 |
| 50 | purine nucleobase biosynthetic process (GO:0009113) | 2.96961840 |
| 51 | microtubule-based movement (GO:0007018) | 2.96436135 |
| 52 | DNA replication-independent nucleosome organization (GO:0034724) | 2.94073343 |
| 53 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.94073343 |
| 54 | microtubule depolymerization (GO:0007019) | 2.93543187 |
| 55 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.92875999 |
| 56 | negative regulation of ligase activity (GO:0051352) | 2.92875999 |
| 57 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.90901580 |
| 58 | ATP synthesis coupled proton transport (GO:0015986) | 2.90901580 |
| 59 | nodal signaling pathway (GO:0038092) | 2.89684313 |
| 60 | microtubule polymerization or depolymerization (GO:0031109) | 2.87584385 |
| 61 | termination of RNA polymerase III transcription (GO:0006386) | 2.87502116 |
| 62 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.87502116 |
| 63 | sperm capacitation (GO:0048240) | 2.85123327 |
| 64 | response to xenobiotic stimulus (GO:0009410) | 2.84550856 |
| 65 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.83985507 |
| 66 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.83690314 |
| 67 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.82389488 |
| 68 | diterpenoid biosynthetic process (GO:0016102) | 2.81564999 |
| 69 | negative regulation of T cell differentiation in thymus (GO:0033085) | 2.81190794 |
| 70 | IMP biosynthetic process (GO:0006188) | 2.79347203 |
| 71 | respiratory chain complex IV assembly (GO:0008535) | 2.76781081 |
| 72 | GTP biosynthetic process (GO:0006183) | 2.75481262 |
| 73 | DNA damage response, detection of DNA damage (GO:0042769) | 2.74363695 |
| 74 | hyperosmotic salinity response (GO:0042538) | 2.70596960 |
| 75 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.70265144 |
| 76 | terpenoid biosynthetic process (GO:0016114) | 2.65544427 |
| 77 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.65322190 |
| 78 | electron transport chain (GO:0022900) | 2.63677561 |
| 79 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 2.63562750 |
| 80 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 2.63562750 |
| 81 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 2.63562750 |
| 82 | negative regulation of sister chromatid segregation (GO:0033046) | 2.63562750 |
| 83 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 2.63562750 |
| 84 | anterior/posterior axis specification, embryo (GO:0008595) | 2.63519801 |
| 85 | cell projection assembly (GO:0030031) | 2.62121453 |
| 86 | cullin deneddylation (GO:0010388) | 2.61581537 |
| 87 | IMP metabolic process (GO:0046040) | 2.61537445 |
| 88 | respiratory electron transport chain (GO:0022904) | 2.61317091 |
| 89 | ribosome assembly (GO:0042255) | 2.60801143 |
| 90 | regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902253) | 2.60421464 |
| 91 | DNA double-strand break processing (GO:0000729) | 2.60214688 |
| 92 | determination of left/right symmetry (GO:0007368) | 2.59745471 |
| 93 | negative regulation of JUN kinase activity (GO:0043508) | 2.57007199 |
| 94 | retinoic acid metabolic process (GO:0042573) | 2.56795530 |
| 95 | lateral ventricle development (GO:0021670) | 2.55236159 |
| 96 | response to X-ray (GO:0010165) | 2.54106755 |
| 97 | histone H2A acetylation (GO:0043968) | 2.53220790 |
| 98 | negative regulation of chromosome segregation (GO:0051985) | 2.52947303 |
| 99 | axonemal dynein complex assembly (GO:0070286) | 13.4780320 |
| 100 | cilium movement (GO:0003341) | 10.1289657 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.15151997 |
| 2 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.80284203 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.52242090 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.11628808 |
| 5 | E2F7_22180533_ChIP-Seq_HELA_Human | 3.04257342 |
| 6 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.88402571 |
| 7 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.61337370 |
| 8 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.50491896 |
| 9 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.50308445 |
| 10 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.47997075 |
| 11 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.40634078 |
| 12 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.38661658 |
| 13 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.37537404 |
| 14 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.37076851 |
| 15 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.26685339 |
| 16 | VDR_22108803_ChIP-Seq_LS180_Human | 2.26565055 |
| 17 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.09951658 |
| 18 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 2.09633796 |
| 19 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 2.05942394 |
| 20 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.05515680 |
| 21 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.03260377 |
| 22 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.90866691 |
| 23 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.89756186 |
| 24 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.79509444 |
| 25 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.74716013 |
| 26 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.73746146 |
| 27 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.73724865 |
| 28 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.72943887 |
| 29 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.72485471 |
| 30 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.70452880 |
| 31 | EWS_26573619_Chip-Seq_HEK293_Human | 1.68974415 |
| 32 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.66909028 |
| 33 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.59822992 |
| 34 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.59714567 |
| 35 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.57260983 |
| 36 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.56701502 |
| 37 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 1.53722434 |
| 38 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.50064887 |
| 39 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.48037486 |
| 40 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.47051269 |
| 41 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.46137396 |
| 42 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.45821993 |
| 43 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.44765411 |
| 44 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.44571009 |
| 45 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.43976567 |
| 46 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.43580791 |
| 47 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.43580791 |
| 48 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.43580791 |
| 49 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.42230689 |
| 50 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.39869937 |
| 51 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.39758713 |
| 52 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.39725525 |
| 53 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.35218700 |
| 54 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.34134275 |
| 55 | FUS_26573619_Chip-Seq_HEK293_Human | 1.33867832 |
| 56 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.33423136 |
| 57 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.32392078 |
| 58 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.31618075 |
| 59 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.30841919 |
| 60 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.30330337 |
| 61 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.30048833 |
| 62 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.29724791 |
| 63 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.28929968 |
| 64 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.28445941 |
| 65 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.21473800 |
| 66 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.20155949 |
| 67 | P300_19829295_ChIP-Seq_ESCs_Human | 1.19694754 |
| 68 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 1.17182708 |
| 69 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.16364929 |
| 70 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.14867063 |
| 71 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.14341614 |
| 72 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.13705109 |
| 73 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.12003470 |
| 74 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.11325526 |
| 75 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.10003051 |
| 76 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.09540628 |
| 77 | PHF8_20622853_ChIP-Seq_HELA_Human | 1.09265120 |
| 78 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.08884777 |
| 79 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.08706079 |
| 80 | RBPJ_21746931_ChIP-Seq_IB4_Human | 1.07658039 |
| 81 | ETV1_20927104_ChIP-Seq_GIST48_Human | 1.04223680 |
| 82 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.03133737 |
| 83 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.02475683 |
| 84 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.02433660 |
| 85 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.00704293 |
| 86 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.00006704 |
| 87 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.99686379 |
| 88 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.99248247 |
| 89 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.98841833 |
| 90 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 0.98736165 |
| 91 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 0.97085335 |
| 92 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.95239844 |
| 93 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.95239844 |
| 94 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.94111993 |
| 95 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.92893581 |
| 96 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 0.91132107 |
| 97 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.90920815 |
| 98 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 0.90780762 |
| 99 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.90145780 |
| 100 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 0.87813978 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003941_abnormal_skin_development | 4.28165584 |
| 2 | MP0004133_heterotaxia | 4.05125640 |
| 3 | MP0001984_abnormal_olfaction | 3.35628932 |
| 4 | MP0008875_abnormal_xenobiotic_pharmacok | 3.03425157 |
| 5 | MP0003890_abnormal_embryonic-extraembry | 2.99980068 |
| 6 | MP0004957_abnormal_blastocyst_morpholog | 2.94298144 |
| 7 | MP0002653_abnormal_ependyma_morphology | 2.93393979 |
| 8 | MP0008789_abnormal_olfactory_epithelium | 2.84114913 |
| 9 | MP0008058_abnormal_DNA_repair | 2.64730221 |
| 10 | MP0003693_abnormal_embryo_hatching | 2.62382384 |
| 11 | MP0001188_hyperpigmentation | 2.58818410 |
| 12 | MP0002132_abnormal_respiratory_system | 2.46279737 |
| 13 | MP0002277_abnormal_respiratory_mucosa | 2.35242193 |
| 14 | MP0003718_maternal_effect | 2.30618482 |
| 15 | MP0008877_abnormal_DNA_methylation | 2.28094504 |
| 16 | MP0002254_reproductive_system_inflammat | 2.19116850 |
| 17 | MP0003806_abnormal_nucleotide_metabolis | 2.17134973 |
| 18 | MP0010094_abnormal_chromosome_stability | 2.09236882 |
| 19 | MP0005499_abnormal_olfactory_system | 2.04422934 |
| 20 | MP0005394_taste/olfaction_phenotype | 2.04422934 |
| 21 | MP0001293_anophthalmia | 1.96804187 |
| 22 | MP0003111_abnormal_nucleus_morphology | 1.82993164 |
| 23 | MP0008932_abnormal_embryonic_tissue | 1.76970365 |
| 24 | MP0004043_abnormal_pH_regulation | 1.72486378 |
| 25 | MP0004019_abnormal_vitamin_homeostasis | 1.69529837 |
| 26 | MP0003186_abnormal_redox_activity | 1.63542101 |
| 27 | MP0003119_abnormal_digestive_system | 1.63284215 |
| 28 | MP0010030_abnormal_orbit_morphology | 1.61862119 |
| 29 | MP0008007_abnormal_cellular_replicative | 1.59404143 |
| 30 | MP0003937_abnormal_limbs/digits/tail_de | 1.57405447 |
| 31 | MP0003077_abnormal_cell_cycle | 1.53433003 |
| 32 | MP0000566_synostosis | 1.51070793 |
| 33 | MP0003136_yellow_coat_color | 1.50723675 |
| 34 | MP0006072_abnormal_retinal_apoptosis | 1.50299166 |
| 35 | MP0008057_abnormal_DNA_replication | 1.47988865 |
| 36 | MP0006036_abnormal_mitochondrial_physio | 1.47911179 |
| 37 | MP0003283_abnormal_digestive_organ | 1.41501747 |
| 38 | MP0002160_abnormal_reproductive_system | 1.39057507 |
| 39 | MP0002084_abnormal_developmental_patter | 1.38379529 |
| 40 | MP0009672_abnormal_birth_weight | 1.36400076 |
| 41 | MP0002233_abnormal_nose_morphology | 1.35904907 |
| 42 | MP0003123_paternal_imprinting | 1.31262414 |
| 43 | MP0009379_abnormal_foot_pigmentation | 1.30927010 |
| 44 | MP0001485_abnormal_pinna_reflex | 1.28331696 |
| 45 | MP0002102_abnormal_ear_morphology | 1.27588158 |
| 46 | MP0003786_premature_aging | 1.24373012 |
| 47 | MP0006292_abnormal_olfactory_placode | 1.22981610 |
| 48 | MP0003195_calcinosis | 1.22851546 |
| 49 | MP0005395_other_phenotype | 1.22774336 |
| 50 | MP0009703_decreased_birth_body | 1.22035084 |
| 51 | MP0002085_abnormal_embryonic_tissue | 1.19460333 |
| 52 | MP0000579_abnormal_nail_morphology | 1.15930714 |
| 53 | MP0006035_abnormal_mitochondrial_morpho | 1.11934834 |
| 54 | MP0001529_abnormal_vocalization | 1.10447064 |
| 55 | MP0010234_abnormal_vibrissa_follicle | 1.08788217 |
| 56 | MP0001929_abnormal_gametogenesis | 1.07877083 |
| 57 | MP0002111_abnormal_tail_morphology | 1.07456339 |
| 58 | MP0005377_hearing/vestibular/ear_phenot | 1.05743857 |
| 59 | MP0003878_abnormal_ear_physiology | 1.05743857 |
| 60 | MP0001730_embryonic_growth_arrest | 1.05299284 |
| 61 | MP0005623_abnormal_meninges_morphology | 1.04976254 |
| 62 | MP0002734_abnormal_mechanical_nocicepti | 1.02944604 |
| 63 | MP0009780_abnormal_chondrocyte_physiolo | 1.02569368 |
| 64 | MP0002282_abnormal_trachea_morphology | 0.99796306 |
| 65 | MP0003567_abnormal_fetal_cardiomyocyte | 0.99445489 |
| 66 | MP0008995_early_reproductive_senescence | 0.97310783 |
| 67 | MP0002796_impaired_skin_barrier | 0.96415421 |
| 68 | MP0005253_abnormal_eye_physiology | 0.95173125 |
| 69 | MP0003121_genomic_imprinting | 0.93157822 |
| 70 | MP0005220_abnormal_exocrine_pancreas | 0.92706225 |
| 71 | MP0005075_abnormal_melanosome_morpholog | 0.92534741 |
| 72 | MP0002736_abnormal_nociception_after | 0.91358625 |
| 73 | MP0000350_abnormal_cell_proliferation | 0.91216711 |
| 74 | MP0003787_abnormal_imprinting | 0.88738781 |
| 75 | MP0001286_abnormal_eye_development | 0.87589457 |
| 76 | MP0003011_delayed_dark_adaptation | 0.87242360 |
| 77 | MP0000358_abnormal_cell_content/ | 0.87071332 |
| 78 | MP0002638_abnormal_pupillary_reflex | 0.85877148 |
| 79 | MP0009046_muscle_twitch | 0.85696541 |
| 80 | MP0003122_maternal_imprinting | 0.84921850 |
| 81 | MP0001324_abnormal_eye_pigmentation | 0.84804567 |
| 82 | MP0002090_abnormal_vision | 0.84399742 |
| 83 | MP0010678_abnormal_skin_adnexa | 0.83687669 |
| 84 | MP0010352_gastrointestinal_tract_polyps | 0.82109737 |
| 85 | MP0005380_embryogenesis_phenotype | 0.81393320 |
| 86 | MP0001672_abnormal_embryogenesis/_devel | 0.81393320 |
| 87 | MP0005636_abnormal_mineral_homeostasis | 0.81331545 |
| 88 | MP0003698_abnormal_male_reproductive | 0.79190019 |
| 89 | MP0002080_prenatal_lethality | 0.79032465 |
| 90 | MP0002938_white_spotting | 0.79023142 |
| 91 | MP0002909_abnormal_adrenal_gland | 0.78097782 |
| 92 | MP0001145_abnormal_male_reproductive | 0.77441062 |
| 93 | MP0001697_abnormal_embryo_size | 0.76897953 |
| 94 | MP0000653_abnormal_sex_gland | 0.75384735 |
| 95 | MP0000383_abnormal_hair_follicle | 0.74881089 |
| 96 | MP0002210_abnormal_sex_determination | 0.74041118 |
| 97 | MP0000631_abnormal_neuroendocrine_gland | 0.73815678 |
| 98 | MP0005551_abnormal_eye_electrophysiolog | 0.72299737 |
| 99 | MP0005389_reproductive_system_phenotype | 0.72259887 |
| 100 | MP0001177_atelectasis | 0.72008978 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormal respiratory motile cilium physiology (HP:0012261) | 9.48321073 |
| 2 | Abnormal respiratory motile cilium morphology (HP:0005938) | 9.18810115 |
| 3 | Abnormal respiratory epithelium morphology (HP:0012253) | 9.18810115 |
| 4 | Abnormal ciliary motility (HP:0012262) | 9.06186708 |
| 5 | Rhinitis (HP:0012384) | 8.80237331 |
| 6 | Absent/shortened dynein arms (HP:0200106) | 8.73110320 |
| 7 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 8.73110320 |
| 8 | Chronic bronchitis (HP:0004469) | 7.56116117 |
| 9 | Bronchiectasis (HP:0002110) | 6.30134108 |
| 10 | Nasal polyposis (HP:0100582) | 4.82930478 |
| 11 | Pancreatic fibrosis (HP:0100732) | 3.81318593 |
| 12 | Abnormality of the nasal mucosa (HP:0000433) | 3.77893596 |
| 13 | Bronchitis (HP:0012387) | 3.56568550 |
| 14 | Infertility (HP:0000789) | 3.55774678 |
| 15 | True hermaphroditism (HP:0010459) | 3.52412786 |
| 16 | Occipital encephalocele (HP:0002085) | 3.29551522 |
| 17 | Chronic sinusitis (HP:0011109) | 3.26730332 |
| 18 | Pancreatic cysts (HP:0001737) | 3.18775681 |
| 19 | Recurrent sinusitis (HP:0011108) | 3.14180290 |
| 20 | Abnormality of midbrain morphology (HP:0002418) | 2.85052316 |
| 21 | Molar tooth sign on MRI (HP:0002419) | 2.85052316 |
| 22 | Cystic liver disease (HP:0006706) | 2.73803236 |
| 23 | Recurrent otitis media (HP:0000403) | 2.73567428 |
| 24 | Nephronophthisis (HP:0000090) | 2.69227168 |
| 25 | Male infertility (HP:0003251) | 2.63121534 |
| 26 | Anencephaly (HP:0002323) | 2.45344860 |
| 27 | Postaxial foot polydactyly (HP:0001830) | 2.27686809 |
| 28 | Medial flaring of the eyebrow (HP:0010747) | 2.26648742 |
| 29 | Hyperactive renin-angiotensin system (HP:0000841) | 2.22912428 |
| 30 | Chronic otitis media (HP:0000389) | 2.21672545 |
| 31 | Abnormality of the labia minora (HP:0012880) | 2.21403074 |
| 32 | Abdominal situs inversus (HP:0003363) | 2.19026705 |
| 33 | Abnormality of abdominal situs (HP:0011620) | 2.19026705 |
| 34 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.14712860 |
| 35 | Male pseudohermaphroditism (HP:0000037) | 2.14166932 |
| 36 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.03313365 |
| 37 | Asplenia (HP:0001746) | 2.02996616 |
| 38 | Tubulointerstitial nephritis (HP:0001970) | 2.02332542 |
| 39 | Congenital primary aphakia (HP:0007707) | 2.02035846 |
| 40 | Sclerocornea (HP:0000647) | 2.01693289 |
| 41 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 10.6188790 |
| 42 | Supernumerary spleens (HP:0009799) | 1.96905125 |
| 43 | Chronic hepatic failure (HP:0100626) | 1.93774385 |
| 44 | Median cleft lip (HP:0000161) | 1.93320282 |
| 45 | Abnormality of the renal medulla (HP:0100957) | 1.92586512 |
| 46 | Gait imbalance (HP:0002141) | 1.91692352 |
| 47 | Acute necrotizing encephalopathy (HP:0006965) | 1.87820634 |
| 48 | Hyperinsulinemic hypoglycemia (HP:0000825) | 1.85904274 |
| 49 | Hypoglycemic seizures (HP:0002173) | 1.85395283 |
| 50 | Congenital hepatic fibrosis (HP:0002612) | 1.84899207 |
| 51 | Carpal bone hypoplasia (HP:0001498) | 1.82322779 |
| 52 | Furrowed tongue (HP:0000221) | 1.80857855 |
| 53 | Atelectasis (HP:0100750) | 1.79482347 |
| 54 | Nephrogenic diabetes insipidus (HP:0009806) | 1.76603818 |
| 55 | Oculomotor apraxia (HP:0000657) | 1.75765227 |
| 56 | Increased hepatocellular lipid droplets (HP:0006565) | 1.75698075 |
| 57 | Vaginal atresia (HP:0000148) | 1.75270548 |
| 58 | Genital tract atresia (HP:0001827) | 1.74003062 |
| 59 | Preaxial hand polydactyly (HP:0001177) | 1.73709662 |
| 60 | Acute encephalopathy (HP:0006846) | 1.70441451 |
| 61 | Postaxial hand polydactyly (HP:0001162) | 1.68965113 |
| 62 | Colon cancer (HP:0003003) | 1.65425339 |
| 63 | Septo-optic dysplasia (HP:0100842) | 1.56714877 |
| 64 | Facial cleft (HP:0002006) | 1.56601208 |
| 65 | Progressive macrocephaly (HP:0004481) | 1.56459879 |
| 66 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.56158449 |
| 67 | Mitochondrial inheritance (HP:0001427) | 1.55828276 |
| 68 | Lipid accumulation in hepatocytes (HP:0006561) | 1.54533541 |
| 69 | Tubular atrophy (HP:0000092) | 1.54186535 |
| 70 | Abnormal biliary tract physiology (HP:0012439) | 1.54181425 |
| 71 | Bile duct proliferation (HP:0001408) | 1.54181425 |
| 72 | Methylmalonic acidemia (HP:0002912) | 1.51405737 |
| 73 | Renal salt wasting (HP:0000127) | 1.48022890 |
| 74 | Poor coordination (HP:0002370) | 1.46038674 |
| 75 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.44234015 |
| 76 | Abnormality of methionine metabolism (HP:0010901) | 1.42061959 |
| 77 | Increased CSF lactate (HP:0002490) | 1.40107514 |
| 78 | Bilateral microphthalmos (HP:0007633) | 1.37383472 |
| 79 | Hyperglycinemia (HP:0002154) | 1.36248814 |
| 80 | Maternal diabetes (HP:0009800) | 1.33221069 |
| 81 | Cerebral edema (HP:0002181) | 1.32271751 |
| 82 | Central scotoma (HP:0000603) | 1.30465324 |
| 83 | Abnormality of homocysteine metabolism (HP:0010919) | 1.30382657 |
| 84 | Homocystinuria (HP:0002156) | 1.30382657 |
| 85 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.30368559 |
| 86 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.30368559 |
| 87 | Abnormality of serum amino acid levels (HP:0003112) | 1.30337252 |
| 88 | Hepatocellular necrosis (HP:0001404) | 1.30288528 |
| 89 | Hypoplastic female external genitalia (HP:0012815) | 1.29121296 |
| 90 | Abnormality of permanent molar morphology (HP:0011071) | 1.28617474 |
| 91 | Abnormality of the dental root (HP:0006486) | 1.28617474 |
| 92 | Taurodontia (HP:0000679) | 1.28617474 |
| 93 | Nephropathy (HP:0000112) | 1.28445764 |
| 94 | Abolished electroretinogram (ERG) (HP:0000550) | 1.28399958 |
| 95 | Methylmalonic aciduria (HP:0012120) | 1.28219535 |
| 96 | Broad foot (HP:0001769) | 1.27980203 |
| 97 | Hyperglycinuria (HP:0003108) | 1.26290261 |
| 98 | Megaloblastic anemia (HP:0001889) | 1.25974558 |
| 99 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.25033481 |
| 100 | Abnormality of macular pigmentation (HP:0008002) | 1.24702712 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MST4 | 5.46342516 |
| 2 | MAPK15 | 5.15570274 |
| 3 | TTK | 3.68455879 |
| 4 | PBK | 3.00354717 |
| 5 | TSSK6 | 2.99073385 |
| 6 | NME1 | 2.98062358 |
| 7 | CDC7 | 2.96938236 |
| 8 | BUB1 | 2.76903614 |
| 9 | STK16 | 2.64987869 |
| 10 | VRK2 | 2.46052846 |
| 11 | TNIK | 2.39133984 |
| 12 | SRPK1 | 2.33369850 |
| 13 | MKNK2 | 2.32879342 |
| 14 | PLK3 | 2.07118450 |
| 15 | ACVR1B | 1.82170432 |
| 16 | BRSK2 | 1.79793183 |
| 17 | WNK3 | 1.77725903 |
| 18 | PLK1 | 1.64510595 |
| 19 | ZAK | 1.61954877 |
| 20 | EIF2AK3 | 1.60188773 |
| 21 | STK24 | 1.58813796 |
| 22 | MKNK1 | 1.57532701 |
| 23 | TAF1 | 1.46551162 |
| 24 | CDK19 | 1.45957525 |
| 25 | PASK | 1.41362689 |
| 26 | BMPR1B | 1.38464472 |
| 27 | PLK4 | 1.38051905 |
| 28 | EPHA2 | 1.36785259 |
| 29 | STK38L | 1.31321166 |
| 30 | TRIM28 | 1.28976941 |
| 31 | VRK1 | 1.27144520 |
| 32 | NLK | 1.18169211 |
| 33 | MAP4K2 | 1.17127057 |
| 34 | DYRK3 | 1.16865002 |
| 35 | DYRK2 | 1.14480859 |
| 36 | EIF2AK1 | 1.13474305 |
| 37 | WEE1 | 1.12394119 |
| 38 | OXSR1 | 1.08324257 |
| 39 | PNCK | 1.06995397 |
| 40 | PAK4 | 0.98469565 |
| 41 | MAP3K12 | 0.94695955 |
| 42 | GRK1 | 0.93484138 |
| 43 | NUAK1 | 0.93177579 |
| 44 | BCR | 0.89207912 |
| 45 | FRK | 0.85026055 |
| 46 | CSNK1G1 | 0.83722091 |
| 47 | NEK1 | 0.77090970 |
| 48 | CHEK2 | 0.74801240 |
| 49 | ERBB3 | 0.73881924 |
| 50 | STK4 | 0.73321306 |
| 51 | CSNK1G2 | 0.68872507 |
| 52 | FGFR2 | 0.67753502 |
| 53 | STK10 | 0.66180225 |
| 54 | AURKA | 0.64960587 |
| 55 | ATR | 0.62791910 |
| 56 | ALK | 0.62091664 |
| 57 | ERBB4 | 0.60873586 |
| 58 | PRKCI | 0.60166320 |
| 59 | MAPKAPK3 | 0.59569706 |
| 60 | ATM | 0.58986175 |
| 61 | AURKB | 0.57850831 |
| 62 | BRSK1 | 0.57070690 |
| 63 | PINK1 | 0.55435182 |
| 64 | NEK6 | 0.54502365 |
| 65 | SMG1 | 0.52751758 |
| 66 | STK3 | 0.49705343 |
| 67 | TLK1 | 0.47031771 |
| 68 | PTK2B | 0.46953529 |
| 69 | CSNK2A1 | 0.46910759 |
| 70 | PLK2 | 0.43739198 |
| 71 | CSNK1E | 0.43665292 |
| 72 | CSNK1G3 | 0.43174253 |
| 73 | CSNK2A2 | 0.43143497 |
| 74 | MAP3K8 | 0.43047605 |
| 75 | PRKDC | 0.41736304 |
| 76 | MAP3K2 | 0.41668985 |
| 77 | MAP3K4 | 0.39177411 |
| 78 | CHEK1 | 0.37395088 |
| 79 | EIF2AK2 | 0.36333585 |
| 80 | TGFBR1 | 0.36057269 |
| 81 | INSRR | 0.35658759 |
| 82 | CASK | 0.35616737 |
| 83 | LATS1 | 0.32965876 |
| 84 | PRKCG | 0.31502869 |
| 85 | FGFR1 | 0.30888766 |
| 86 | NME2 | 0.29767417 |
| 87 | RPS6KA5 | 0.27956715 |
| 88 | MAP3K10 | 0.27111501 |
| 89 | PAK1 | 0.26232798 |
| 90 | EGFR | 0.25884741 |
| 91 | DMPK | 0.25759432 |
| 92 | DYRK1A | 0.24127499 |
| 93 | CSNK1A1 | 0.23732900 |
| 94 | CDK3 | 0.23161803 |
| 95 | STK39 | 0.22993929 |
| 96 | ADRBK2 | 0.22779398 |
| 97 | CDK1 | 0.21699249 |
| 98 | ERBB2 | 0.20738811 |
| 99 | CDK2 | 0.20149005 |
| 100 | TIE1 | 0.19934061 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.01983150 |
| 2 | Huntingtons disease_Homo sapiens_hsa05016 | 2.89400523 |
| 3 | Mismatch repair_Homo sapiens_hsa03430 | 2.76392997 |
| 4 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 2.62464124 |
| 5 | Protein export_Homo sapiens_hsa03060 | 2.60353585 |
| 6 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.56228307 |
| 7 | RNA polymerase_Homo sapiens_hsa03020 | 2.54539417 |
| 8 | Glutathione metabolism_Homo sapiens_hsa00480 | 2.38486378 |
| 9 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.24762896 |
| 10 | Parkinsons disease_Homo sapiens_hsa05012 | 2.16454866 |
| 11 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 2.01607305 |
| 12 | Ribosome_Homo sapiens_hsa03010 | 1.97331030 |
| 13 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.96679029 |
| 14 | DNA replication_Homo sapiens_hsa03030 | 1.95838792 |
| 15 | Homologous recombination_Homo sapiens_hsa03440 | 1.95215642 |
| 16 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.88145681 |
| 17 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.82776589 |
| 18 | RNA transport_Homo sapiens_hsa03013 | 1.72204734 |
| 19 | Spliceosome_Homo sapiens_hsa03040 | 1.71991630 |
| 20 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.67097863 |
| 21 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.65465284 |
| 22 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.63111264 |
| 23 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.63044657 |
| 24 | Basal transcription factors_Homo sapiens_hsa03022 | 1.58162728 |
| 25 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.57194206 |
| 26 | Histidine metabolism_Homo sapiens_hsa00340 | 1.55624546 |
| 27 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.54064561 |
| 28 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.50279012 |
| 29 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.49658550 |
| 30 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.45521416 |
| 31 | RNA degradation_Homo sapiens_hsa03018 | 1.43853312 |
| 32 | Alzheimers disease_Homo sapiens_hsa05010 | 1.43316256 |
| 33 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.37743847 |
| 34 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.36622544 |
| 35 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.32073411 |
| 36 | Retinol metabolism_Homo sapiens_hsa00830 | 1.31593029 |
| 37 | Base excision repair_Homo sapiens_hsa03410 | 1.31006404 |
| 38 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.27259013 |
| 39 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.27159541 |
| 40 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.24086057 |
| 41 | Purine metabolism_Homo sapiens_hsa00230 | 1.22643776 |
| 42 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.22242362 |
| 43 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.20617318 |
| 44 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.17903319 |
| 45 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.17756246 |
| 46 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.15489657 |
| 47 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.15173117 |
| 48 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.14774761 |
| 49 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.11653784 |
| 50 | Cell cycle_Homo sapiens_hsa04110 | 1.06809392 |
| 51 | Peroxisome_Homo sapiens_hsa04146 | 0.99093710 |
| 52 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.97366317 |
| 53 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.96868783 |
| 54 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.95984775 |
| 55 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.92898505 |
| 56 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.91461636 |
| 57 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.87278478 |
| 58 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.86046851 |
| 59 | Tight junction_Homo sapiens_hsa04530 | 0.85363463 |
| 60 | Phototransduction_Homo sapiens_hsa04744 | 0.84658311 |
| 61 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.83879131 |
| 62 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.83358782 |
| 63 | Metabolic pathways_Homo sapiens_hsa01100 | 0.81225833 |
| 64 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.80465893 |
| 65 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.80005797 |
| 66 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.79362079 |
| 67 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.77690042 |
| 68 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.77053828 |
| 69 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.74241164 |
| 70 | Carbon metabolism_Homo sapiens_hsa01200 | 0.73598280 |
| 71 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.70184263 |
| 72 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.66322845 |
| 73 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.65927095 |
| 74 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.64429603 |
| 75 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.64323030 |
| 76 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.59858081 |
| 77 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.59348697 |
| 78 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.55564461 |
| 79 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.49030769 |
| 80 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.46399105 |
| 81 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.45772234 |
| 82 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.45338663 |
| 83 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.45216457 |
| 84 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.43018905 |
| 85 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.41948452 |
| 86 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.40778984 |
| 87 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.40215244 |
| 88 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.38936752 |
| 89 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.37728508 |
| 90 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.35723991 |
| 91 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.35039468 |
| 92 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.32528214 |
| 93 | Nicotine addiction_Homo sapiens_hsa05033 | 0.31628878 |
| 94 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.31118249 |
| 95 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.30898540 |
| 96 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.30270781 |
| 97 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.29942247 |
| 98 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.29707145 |
| 99 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.28955911 |
| 100 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.27763582 |

