Rank | Gene Set | Z-score |
---|---|---|
1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.77506420 |
2 | chromatin remodeling at centromere (GO:0031055) | 3.59499150 |
3 | presynaptic membrane assembly (GO:0097105) | 3.45066864 |
4 | ATP synthesis coupled proton transport (GO:0015986) | 3.40844498 |
5 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.40844498 |
6 | behavioral response to nicotine (GO:0035095) | 3.40019119 |
7 | protein neddylation (GO:0045116) | 3.31721733 |
8 | CENP-A containing nucleosome assembly (GO:0034080) | 3.30084121 |
9 | respiratory chain complex IV assembly (GO:0008535) | 3.28268612 |
10 | protein complex biogenesis (GO:0070271) | 3.19399651 |
11 | chaperone-mediated protein transport (GO:0072321) | 3.19180339 |
12 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.15699083 |
13 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.15050751 |
14 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.15050751 |
15 | regulation of gene silencing by RNA (GO:0060966) | 3.12532762 |
16 | regulation of posttranscriptional gene silencing (GO:0060147) | 3.12532762 |
17 | regulation of gene silencing by miRNA (GO:0060964) | 3.12532762 |
18 | DNA double-strand break processing (GO:0000729) | 3.10671689 |
19 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.10186701 |
20 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.08647874 |
21 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.08647874 |
22 | NADH dehydrogenase complex assembly (GO:0010257) | 3.08647874 |
23 | secondary metabolite biosynthetic process (GO:0044550) | 3.08170772 |
24 | histone exchange (GO:0043486) | 3.07913872 |
25 | replication fork processing (GO:0031297) | 3.05739691 |
26 | cullin deneddylation (GO:0010388) | 3.04825379 |
27 | retinal ganglion cell axon guidance (GO:0031290) | 3.03804622 |
28 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.03128153 |
29 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 3.00688016 |
30 | regulation of translation, ncRNA-mediated (GO:0045974) | 3.00688016 |
31 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 3.00688016 |
32 | presynaptic membrane organization (GO:0097090) | 2.99278546 |
33 | cytochrome complex assembly (GO:0017004) | 2.99170559 |
34 | otic vesicle formation (GO:0030916) | 2.96069298 |
35 | limb bud formation (GO:0060174) | 2.93735326 |
36 | kinetochore assembly (GO:0051382) | 2.93291326 |
37 | somite development (GO:0061053) | 2.92574822 |
38 | platelet dense granule organization (GO:0060155) | 2.92063766 |
39 | lateral sprouting from an epithelium (GO:0060601) | 2.90471729 |
40 | protein deneddylation (GO:0000338) | 2.90366927 |
41 | kidney morphogenesis (GO:0060993) | 2.89385632 |
42 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.88284717 |
43 | nonmotile primary cilium assembly (GO:0035058) | 2.88024039 |
44 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.82635040 |
45 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.81993665 |
46 | regulation of non-canonical Wnt signaling pathway (GO:2000050) | 2.80713909 |
47 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.80527779 |
48 | L-serine metabolic process (GO:0006563) | 2.79568107 |
49 | pyrimidine nucleobase catabolic process (GO:0006208) | 2.78843265 |
50 | DNA damage response, detection of DNA damage (GO:0042769) | 2.77733914 |
51 | intraciliary transport (GO:0042073) | 2.74409739 |
52 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.73198599 |
53 | epithelial cilium movement (GO:0003351) | 2.71254244 |
54 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.70759780 |
55 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.69122743 |
56 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.69122743 |
57 | protein K6-linked ubiquitination (GO:0085020) | 2.64837286 |
58 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.62007050 |
59 | regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095) | 2.61553895 |
60 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.58277028 |
61 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.58277028 |
62 | postsynaptic membrane organization (GO:0001941) | 2.58241364 |
63 | DNA replication-independent nucleosome organization (GO:0034724) | 2.56511343 |
64 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.56511343 |
65 | DNA replication checkpoint (GO:0000076) | 2.53517478 |
66 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.52620156 |
67 | termination of RNA polymerase III transcription (GO:0006386) | 2.52620156 |
68 | melanin biosynthetic process (GO:0042438) | 2.52111816 |
69 | DNA strand renaturation (GO:0000733) | 2.52033920 |
70 | serine family amino acid catabolic process (GO:0009071) | 2.51392474 |
71 | lysine catabolic process (GO:0006554) | 2.50463908 |
72 | lysine metabolic process (GO:0006553) | 2.50463908 |
73 | peptidyl-histidine modification (GO:0018202) | 2.49898923 |
74 | cilium morphogenesis (GO:0060271) | 2.48863610 |
75 | protein-cofactor linkage (GO:0018065) | 2.48715251 |
76 | proteasome assembly (GO:0043248) | 2.47927689 |
77 | regulation of mesoderm development (GO:2000380) | 2.47834665 |
78 | kinetochore organization (GO:0051383) | 2.45783547 |
79 | reciprocal meiotic recombination (GO:0007131) | 2.44394955 |
80 | reciprocal DNA recombination (GO:0035825) | 2.44394955 |
81 | lung-associated mesenchyme development (GO:0060484) | 2.44055360 |
82 | ubiquinone metabolic process (GO:0006743) | 2.43890569 |
83 | negative regulation of telomere maintenance (GO:0032205) | 2.42949874 |
84 | recombinational repair (GO:0000725) | 2.41177946 |
85 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.40121323 |
86 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.40121323 |
87 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 2.39695255 |
88 | cornea development in camera-type eye (GO:0061303) | 2.39039577 |
89 | electron transport chain (GO:0022900) | 2.38652302 |
90 | respiratory electron transport chain (GO:0022904) | 2.38628676 |
91 | glycine metabolic process (GO:0006544) | 2.37308457 |
92 | aldehyde catabolic process (GO:0046185) | 2.37262997 |
93 | double-strand break repair via homologous recombination (GO:0000724) | 2.36868346 |
94 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 2.36520269 |
95 | synapsis (GO:0007129) | 2.36448846 |
96 | DNA ligation (GO:0006266) | 2.34449481 |
97 | dorsal/ventral axis specification (GO:0009950) | 2.34176714 |
98 | protein polyglutamylation (GO:0018095) | 2.30813421 |
99 | ubiquinone biosynthetic process (GO:0006744) | 2.30659210 |
100 | aspartate family amino acid catabolic process (GO:0009068) | 2.29666932 |
Rank | Gene Set | Z-score |
---|---|---|
1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.11970761 |
2 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.05339573 |
3 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.78756301 |
4 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.71929219 |
5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.71221788 |
6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.63679070 |
7 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.59079053 |
8 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.56577636 |
9 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.52998211 |
10 | VDR_22108803_ChIP-Seq_LS180_Human | 2.49672813 |
11 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.42860277 |
12 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.38695581 |
13 | FUS_26573619_Chip-Seq_HEK293_Human | 2.33880184 |
14 | EWS_26573619_Chip-Seq_HEK293_Human | 2.27974172 |
15 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.09928998 |
16 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.09630665 |
17 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 2.09116868 |
18 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.06149070 |
19 | P300_19829295_ChIP-Seq_ESCs_Human | 2.02551964 |
20 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.01457458 |
21 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.92839342 |
22 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.92401001 |
23 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.90809304 |
24 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.87010573 |
25 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.81781745 |
26 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.80107976 |
27 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.76229297 |
28 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.75630288 |
29 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.73705795 |
30 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.72811594 |
31 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.72340414 |
32 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.70305835 |
33 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.67455619 |
34 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.59429752 |
35 | * SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.58860403 |
36 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.55297582 |
37 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.50106175 |
38 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.46666335 |
39 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.41109788 |
40 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.38919702 |
41 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.36961742 |
42 | * NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.36958368 |
43 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.36599796 |
44 | * EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.31420161 |
45 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.31113012 |
46 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.27769622 |
47 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.26190284 |
48 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.24981645 |
49 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.23288092 |
50 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.21821953 |
51 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.21404867 |
52 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.19291091 |
53 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.18113202 |
54 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.17950249 |
55 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.17225703 |
56 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.15558673 |
57 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.15488624 |
58 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.14912227 |
59 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.13679463 |
60 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.13360361 |
61 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.12890531 |
62 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.12255984 |
63 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.11784290 |
64 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.11784290 |
65 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.11537599 |
66 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.10907310 |
67 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.10340657 |
68 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.10324750 |
69 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.10213967 |
70 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.09857192 |
71 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.09734464 |
72 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.09618843 |
73 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.08730092 |
74 | * ER_23166858_ChIP-Seq_MCF-7_Human | 1.07469855 |
75 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.07125689 |
76 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.05625476 |
77 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.05350546 |
78 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.05350546 |
79 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.04819016 |
80 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.04128759 |
81 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.02847644 |
82 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.02695386 |
83 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.02124765 |
84 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 1.01734233 |
85 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.01311955 |
86 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.01301522 |
87 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.00248127 |
88 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.00248127 |
89 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.97852986 |
90 | AR_25329375_ChIP-Seq_VCAP_Human | 0.97125484 |
91 | * FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.96770443 |
92 | * FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.96770443 |
93 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.95340882 |
94 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.94494650 |
95 | TTF2_22483619_ChIP-Seq_HELA_Human | 0.94171893 |
96 | E2F7_22180533_ChIP-Seq_HELA_Human | 0.93708897 |
97 | STAT3_23295773_ChIP-Seq_U87_Human | 0.93481240 |
98 | TCF4_23295773_ChIP-Seq_U87_Human | 0.92582521 |
99 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.92047326 |
100 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.92005016 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003136_yellow_coat_color | 4.56438815 |
2 | MP0000372_irregular_coat_pigmentation | 3.35630692 |
3 | MP0005171_absent_coat_pigmentation | 3.25883683 |
4 | MP0006292_abnormal_olfactory_placode | 3.18542575 |
5 | MP0002938_white_spotting | 3.00738076 |
6 | MP0002102_abnormal_ear_morphology | 2.74070376 |
7 | MP0010030_abnormal_orbit_morphology | 2.37930391 |
8 | MP0008877_abnormal_DNA_methylation | 2.23447167 |
9 | MP0001293_anophthalmia | 2.23266206 |
10 | MP0003122_maternal_imprinting | 1.91814521 |
11 | MP0003878_abnormal_ear_physiology | 1.88427250 |
12 | MP0005377_hearing/vestibular/ear_phenot | 1.88427250 |
13 | MP0004133_heterotaxia | 1.84749230 |
14 | MP0006072_abnormal_retinal_apoptosis | 1.80617617 |
15 | MP0008058_abnormal_DNA_repair | 1.80497165 |
16 | MP0002653_abnormal_ependyma_morphology | 1.77906637 |
17 | MP0005253_abnormal_eye_physiology | 1.73088968 |
18 | MP0005551_abnormal_eye_electrophysiolog | 1.68779242 |
19 | MP0001529_abnormal_vocalization | 1.66708526 |
20 | MP0005075_abnormal_melanosome_morpholog | 1.66036752 |
21 | MP0003880_abnormal_central_pattern | 1.64947791 |
22 | MP0003011_delayed_dark_adaptation | 1.63039233 |
23 | MP0001984_abnormal_olfaction | 1.60769261 |
24 | MP0003937_abnormal_limbs/digits/tail_de | 1.58184570 |
25 | MP0008789_abnormal_olfactory_epithelium | 1.55851813 |
26 | MP0002736_abnormal_nociception_after | 1.55705939 |
27 | MP0003121_genomic_imprinting | 1.54302804 |
28 | MP0002095_abnormal_skin_pigmentation | 1.51800127 |
29 | MP0010094_abnormal_chromosome_stability | 1.49945631 |
30 | MP0000566_synostosis | 1.49800160 |
31 | MP0005408_hypopigmentation | 1.47982401 |
32 | MP0003787_abnormal_imprinting | 1.47329193 |
33 | MP0002837_dystrophic_cardiac_calcinosis | 1.46805456 |
34 | MP0000631_abnormal_neuroendocrine_gland | 1.42459163 |
35 | MP0002254_reproductive_system_inflammat | 1.41937106 |
36 | MP0000049_abnormal_middle_ear | 1.41722010 |
37 | MP0003890_abnormal_embryonic-extraembry | 1.40672250 |
38 | MP0002638_abnormal_pupillary_reflex | 1.40455298 |
39 | MP0001968_abnormal_touch/_nociception | 1.38020813 |
40 | MP0002751_abnormal_autonomic_nervous | 1.37949876 |
41 | MP0003195_calcinosis | 1.37848030 |
42 | MP0005174_abnormal_tail_pigmentation | 1.35848319 |
43 | MP0004885_abnormal_endolymph | 1.35258957 |
44 | MP0001485_abnormal_pinna_reflex | 1.33559032 |
45 | MP0001324_abnormal_eye_pigmentation | 1.32162350 |
46 | MP0000778_abnormal_nervous_system | 1.31264935 |
47 | MP0005499_abnormal_olfactory_system | 1.27459945 |
48 | MP0005394_taste/olfaction_phenotype | 1.27459945 |
49 | MP0003567_abnormal_fetal_cardiomyocyte | 1.22024411 |
50 | MP0003119_abnormal_digestive_system | 1.20676416 |
51 | MP0002233_abnormal_nose_morphology | 1.20632534 |
52 | MP0003693_abnormal_embryo_hatching | 1.20104709 |
53 | MP0005248_abnormal_Harderian_gland | 1.16344309 |
54 | MP0003718_maternal_effect | 1.14754142 |
55 | MP0005391_vision/eye_phenotype | 1.13873624 |
56 | MP0003646_muscle_fatigue | 1.13379181 |
57 | MP0004142_abnormal_muscle_tone | 1.12857578 |
58 | MP0003938_abnormal_ear_development | 1.11454029 |
59 | MP0001286_abnormal_eye_development | 1.10762969 |
60 | MP0000026_abnormal_inner_ear | 1.08908944 |
61 | MP0001486_abnormal_startle_reflex | 1.07739280 |
62 | MP0004147_increased_porphyrin_level | 1.03934400 |
63 | MP0006276_abnormal_autonomic_nervous | 1.01068676 |
64 | MP0002272_abnormal_nervous_system | 1.00239976 |
65 | MP0008932_abnormal_embryonic_tissue | 1.00081044 |
66 | MP0005195_abnormal_posterior_eye | 0.99069452 |
67 | MP0002752_abnormal_somatic_nervous | 0.98116826 |
68 | MP0002697_abnormal_eye_size | 0.95310477 |
69 | MP0000569_abnormal_digit_pigmentation | 0.94780159 |
70 | MP0009745_abnormal_behavioral_response | 0.94634855 |
71 | MP0003137_abnormal_impulse_conducting | 0.93871459 |
72 | MP0003755_abnormal_palate_morphology | 0.92696389 |
73 | MP0000647_abnormal_sebaceous_gland | 0.92396459 |
74 | MP0003941_abnormal_skin_development | 0.91845420 |
75 | MP0003111_abnormal_nucleus_morphology | 0.91134517 |
76 | MP0009046_muscle_twitch | 0.90263391 |
77 | MP0005646_abnormal_pituitary_gland | 0.89453549 |
78 | MP0002557_abnormal_social/conspecific_i | 0.84569585 |
79 | MP0001963_abnormal_hearing_physiology | 0.84113721 |
80 | MP0002090_abnormal_vision | 0.82884861 |
81 | MP0003283_abnormal_digestive_organ | 0.81454094 |
82 | MP0001177_atelectasis | 0.81033030 |
83 | MP0004145_abnormal_muscle_electrophysio | 0.80141988 |
84 | MP0002184_abnormal_innervation | 0.79191462 |
85 | MP0003861_abnormal_nervous_system | 0.78316497 |
86 | MP0000955_abnormal_spinal_cord | 0.77004395 |
87 | MP0005187_abnormal_penis_morphology | 0.76787958 |
88 | MP0002734_abnormal_mechanical_nocicepti | 0.76527455 |
89 | MP0002234_abnormal_pharynx_morphology | 0.76138104 |
90 | MP0003698_abnormal_male_reproductive | 0.73327681 |
91 | MP0002111_abnormal_tail_morphology | 0.72085993 |
92 | MP0002572_abnormal_emotion/affect_behav | 0.71951070 |
93 | MP0002210_abnormal_sex_determination | 0.71750173 |
94 | MP0001188_hyperpigmentation | 0.71722643 |
95 | MP0002282_abnormal_trachea_morphology | 0.71506813 |
96 | MP0009697_abnormal_copulation | 0.71038280 |
97 | MP0001929_abnormal_gametogenesis | 0.70953211 |
98 | MP0003186_abnormal_redox_activity | 0.70793083 |
99 | MP0004215_abnormal_myocardial_fiber | 0.68216993 |
100 | MP0002160_abnormal_reproductive_system | 0.67908994 |
Rank | Gene Set | Z-score |
---|---|---|
1 | True hermaphroditism (HP:0010459) | 3.54688743 |
2 | Pancreatic cysts (HP:0001737) | 3.50164626 |
3 | Septo-optic dysplasia (HP:0100842) | 3.45867428 |
4 | Pancreatic fibrosis (HP:0100732) | 3.42123986 |
5 | Abnormality of the labia minora (HP:0012880) | 3.42004823 |
6 | Abnormality of midbrain morphology (HP:0002418) | 3.07769087 |
7 | Molar tooth sign on MRI (HP:0002419) | 3.07769087 |
8 | Colon cancer (HP:0003003) | 3.05785913 |
9 | Nephronophthisis (HP:0000090) | 2.85232346 |
10 | Hyperglycinemia (HP:0002154) | 2.75994793 |
11 | Medial flaring of the eyebrow (HP:0010747) | 2.68456248 |
12 | Anophthalmia (HP:0000528) | 2.58575436 |
13 | Intestinal atresia (HP:0011100) | 2.54762493 |
14 | Congenital stationary night blindness (HP:0007642) | 2.54129695 |
15 | Acute necrotizing encephalopathy (HP:0006965) | 2.49628774 |
16 | Optic nerve hypoplasia (HP:0000609) | 2.47268325 |
17 | Pendular nystagmus (HP:0012043) | 2.41389059 |
18 | Vaginal atresia (HP:0000148) | 2.40753821 |
19 | Abolished electroretinogram (ERG) (HP:0000550) | 2.39183023 |
20 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.38275765 |
21 | Sclerocornea (HP:0000647) | 2.36421225 |
22 | Genital tract atresia (HP:0001827) | 2.36390539 |
23 | Absent septum pellucidum (HP:0001331) | 2.34262539 |
24 | Hyperglycinuria (HP:0003108) | 2.33943631 |
25 | Acute encephalopathy (HP:0006846) | 2.31824999 |
26 | Anencephaly (HP:0002323) | 2.30383255 |
27 | Abnormality of the renal medulla (HP:0100957) | 2.29572769 |
28 | Hypoplasia of the fovea (HP:0007750) | 2.28631773 |
29 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.28631773 |
30 | Meckel diverticulum (HP:0002245) | 2.28135232 |
31 | Abnormality of the ileum (HP:0001549) | 2.25553517 |
32 | Mitochondrial inheritance (HP:0001427) | 2.25444995 |
33 | Abnormal biliary tract physiology (HP:0012439) | 2.24313880 |
34 | Bile duct proliferation (HP:0001408) | 2.24313880 |
35 | Gait imbalance (HP:0002141) | 2.23190856 |
36 | Congenital primary aphakia (HP:0007707) | 2.21949725 |
37 | Increased hepatocellular lipid droplets (HP:0006565) | 2.20632087 |
38 | Cystic liver disease (HP:0006706) | 2.18311605 |
39 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.17678168 |
40 | Abnormality of glycine metabolism (HP:0010895) | 2.17678168 |
41 | Lipid accumulation in hepatocytes (HP:0006561) | 2.17246405 |
42 | Progressive macrocephaly (HP:0004481) | 2.15999828 |
43 | Chronic hepatic failure (HP:0100626) | 2.14729742 |
44 | Bilateral microphthalmos (HP:0007633) | 2.14524705 |
45 | Abnormal lung lobation (HP:0002101) | 2.13065923 |
46 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.10096971 |
47 | Type II lissencephaly (HP:0007260) | 2.10052023 |
48 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.08983832 |
49 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.07868399 |
50 | Supernumerary spleens (HP:0009799) | 2.06669503 |
51 | Nephrogenic diabetes insipidus (HP:0009806) | 2.05531320 |
52 | Preaxial hand polydactyly (HP:0001177) | 2.05182029 |
53 | Increased CSF lactate (HP:0002490) | 2.04689528 |
54 | Abnormality of the fovea (HP:0000493) | 2.03979549 |
55 | Gastrointestinal atresia (HP:0002589) | 2.02099033 |
56 | Aplasia/Hypoplasia affecting the fundus (HP:0008057) | 2.01992970 |
57 | Esophageal atresia (HP:0002032) | 1.99800958 |
58 | Methylmalonic acidemia (HP:0002912) | 1.98896767 |
59 | Abnormality of the septum pellucidum (HP:0007375) | 1.95217118 |
60 | Abnormal number of erythroid precursors (HP:0012131) | 1.93705286 |
61 | Postaxial hand polydactyly (HP:0001162) | 1.92990884 |
62 | Oligodactyly (hands) (HP:0001180) | 1.92749954 |
63 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.92167054 |
64 | Rib fusion (HP:0000902) | 1.91011128 |
65 | Stenosis of the external auditory canal (HP:0000402) | 1.89555966 |
66 | Renal hypoplasia (HP:0000089) | 1.86188658 |
67 | Postaxial foot polydactyly (HP:0001830) | 1.86089276 |
68 | Dandy-Walker malformation (HP:0001305) | 1.85833808 |
69 | Congenital hepatic fibrosis (HP:0002612) | 1.85398781 |
70 | Asplenia (HP:0001746) | 1.84546946 |
71 | Abnormality of serum amino acid levels (HP:0003112) | 1.84498293 |
72 | Triphalangeal thumb (HP:0001199) | 1.84207205 |
73 | Patchy hypopigmentation of hair (HP:0011365) | 1.84030180 |
74 | Bifid tongue (HP:0010297) | 1.82691635 |
75 | Methylmalonic aciduria (HP:0012120) | 1.81359367 |
76 | Abnormality of the renal cortex (HP:0011035) | 1.80167845 |
77 | Ectopic kidney (HP:0000086) | 1.78772003 |
78 | Hypoplastic pelvis (HP:0008839) | 1.77897497 |
79 | Patellar aplasia (HP:0006443) | 1.77500433 |
80 | Reticulocytopenia (HP:0001896) | 1.77014195 |
81 | Decreased central vision (HP:0007663) | 1.75969334 |
82 | Hepatocellular necrosis (HP:0001404) | 1.74235225 |
83 | Holoprosencephaly (HP:0001360) | 1.74214123 |
84 | Aqueductal stenosis (HP:0002410) | 1.73684349 |
85 | Broad foot (HP:0001769) | 1.73397273 |
86 | 3-Methylglutaconic aciduria (HP:0003535) | 1.72675286 |
87 | White forelock (HP:0002211) | 1.72445852 |
88 | Hemivertebrae (HP:0002937) | 1.72279099 |
89 | Attenuation of retinal blood vessels (HP:0007843) | 1.71880096 |
90 | Astigmatism (HP:0000483) | 1.71011472 |
91 | Male pseudohermaphroditism (HP:0000037) | 1.70277482 |
92 | Maternal diabetes (HP:0009800) | 1.69936081 |
93 | Hypoplasia of the pons (HP:0012110) | 1.68773877 |
94 | Cerebellar dysplasia (HP:0007033) | 1.68741025 |
95 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.67365194 |
96 | Abnormality of the pons (HP:0007361) | 1.65546852 |
97 | Optic disc pallor (HP:0000543) | 1.65317936 |
98 | Aplasia/Hypoplasia of the macula (HP:0008059) | 1.63909901 |
99 | Absent thumb (HP:0009777) | 1.63600224 |
100 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.63586811 |
Rank | Gene Set | Z-score |
---|---|---|
1 | WNK3 | 3.03256147 |
2 | FRK | 2.80740242 |
3 | BMPR1B | 2.72584200 |
4 | ZAK | 2.59229329 |
5 | TNIK | 2.59211930 |
6 | MKNK2 | 2.52704450 |
7 | MKNK1 | 2.34147974 |
8 | FGFR2 | 2.24587101 |
9 | NUAK1 | 2.22597758 |
10 | VRK2 | 2.15343586 |
11 | PLK3 | 2.03741165 |
12 | MAP4K2 | 1.96340268 |
13 | BUB1 | 1.94926424 |
14 | ADRBK2 | 1.86525940 |
15 | GRK1 | 1.81896848 |
16 | CDC7 | 1.80405575 |
17 | SRPK1 | 1.78174565 |
18 | DYRK2 | 1.76997187 |
19 | CASK | 1.75519124 |
20 | WEE1 | 1.71928373 |
21 | PLK2 | 1.65578210 |
22 | TRIM28 | 1.62984466 |
23 | MAP3K4 | 1.59858464 |
24 | TTK | 1.56048458 |
25 | STK16 | 1.55694880 |
26 | PINK1 | 1.53376562 |
27 | VRK1 | 1.45772680 |
28 | PLK4 | 1.42098435 |
29 | CSNK1G1 | 1.41257704 |
30 | TSSK6 | 1.35991398 |
31 | ACVR1B | 1.35986768 |
32 | EPHA4 | 1.31362813 |
33 | CSNK1G2 | 1.31123290 |
34 | BCKDK | 1.30936494 |
35 | TAF1 | 1.25594238 |
36 | BRSK2 | 1.23452863 |
37 | WNK4 | 1.22445830 |
38 | CSNK1G3 | 1.20625874 |
39 | STK38L | 1.16781642 |
40 | PLK1 | 1.14430805 |
41 | TLK1 | 1.12593374 |
42 | TGFBR1 | 1.11074285 |
43 | NEK2 | 1.09613000 |
44 | INSRR | 1.09561471 |
45 | OBSCN | 1.08462574 |
46 | NEK1 | 1.06889938 |
47 | CDK19 | 1.06535995 |
48 | NTRK2 | 1.04022850 |
49 | MAP2K7 | 1.01982654 |
50 | MAPK13 | 1.00375075 |
51 | CSNK1A1L | 0.94763106 |
52 | PRKCG | 0.89841382 |
53 | MARK1 | 0.89496717 |
54 | TIE1 | 0.87254314 |
55 | PASK | 0.87147210 |
56 | OXSR1 | 0.86482391 |
57 | BCR | 0.86006549 |
58 | NME1 | 0.85230172 |
59 | ATR | 0.84629481 |
60 | DYRK3 | 0.83202540 |
61 | PAK3 | 0.80393670 |
62 | NLK | 0.77625298 |
63 | EIF2AK3 | 0.76895477 |
64 | BRSK1 | 0.73365497 |
65 | CHEK2 | 0.73278202 |
66 | PRKCE | 0.72076087 |
67 | FGFR1 | 0.71907448 |
68 | ERBB3 | 0.71327975 |
69 | PBK | 0.67422734 |
70 | STK39 | 0.67268614 |
71 | PNCK | 0.63541874 |
72 | STK3 | 0.58566827 |
73 | EPHA3 | 0.58470694 |
74 | DYRK1A | 0.58136574 |
75 | ATM | 0.57900619 |
76 | PHKG2 | 0.56305144 |
77 | PHKG1 | 0.56305144 |
78 | EPHB2 | 0.55783035 |
79 | MST4 | 0.53921493 |
80 | CSNK1A1 | 0.53448423 |
81 | CDK3 | 0.51364673 |
82 | MAPK15 | 0.51297466 |
83 | TYRO3 | 0.46706933 |
84 | AURKB | 0.46494289 |
85 | ERBB2 | 0.43775098 |
86 | UHMK1 | 0.42867604 |
87 | CAMK2A | 0.42704580 |
88 | CSNK1D | 0.40502335 |
89 | PKN1 | 0.39116901 |
90 | RPS6KA4 | 0.38210224 |
91 | PRKDC | 0.38003565 |
92 | CSNK2A1 | 0.37834658 |
93 | PRKACA | 0.37155288 |
94 | MUSK | 0.37152174 |
95 | ADRBK1 | 0.36845998 |
96 | EIF2AK2 | 0.35589843 |
97 | RPS6KA5 | 0.33129694 |
98 | CCNB1 | 0.32545676 |
99 | CSNK1E | 0.31844070 |
100 | PRKACB | 0.30767302 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.74059459 |
2 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.70663823 |
3 | Protein export_Homo sapiens_hsa03060 | 2.51189152 |
4 | Homologous recombination_Homo sapiens_hsa03440 | 2.42472481 |
5 | Parkinsons disease_Homo sapiens_hsa05012 | 2.30743419 |
6 | RNA polymerase_Homo sapiens_hsa03020 | 2.30025875 |
7 | Proteasome_Homo sapiens_hsa03050 | 2.23011287 |
8 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.20531013 |
9 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.16594734 |
10 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.12050521 |
11 | Ribosome_Homo sapiens_hsa03010 | 1.98898998 |
12 | Mismatch repair_Homo sapiens_hsa03430 | 1.94382322 |
13 | Phototransduction_Homo sapiens_hsa04744 | 1.94256116 |
14 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.93190922 |
15 | Basal transcription factors_Homo sapiens_hsa03022 | 1.77573156 |
16 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.76918775 |
17 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.76463515 |
18 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.75914827 |
19 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.75438654 |
20 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.73788467 |
21 | Huntingtons disease_Homo sapiens_hsa05016 | 1.70208301 |
22 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.68414317 |
23 | RNA degradation_Homo sapiens_hsa03018 | 1.66544339 |
24 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.55679326 |
25 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.53886175 |
26 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.51160660 |
27 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.49418929 |
28 | DNA replication_Homo sapiens_hsa03030 | 1.46696822 |
29 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.46435349 |
30 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.45818227 |
31 | Alzheimers disease_Homo sapiens_hsa05010 | 1.40822997 |
32 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.37761682 |
33 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.35235424 |
34 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.34784158 |
35 | Base excision repair_Homo sapiens_hsa03410 | 1.32152701 |
36 | RNA transport_Homo sapiens_hsa03013 | 1.29902256 |
37 | Spliceosome_Homo sapiens_hsa03040 | 1.29533063 |
38 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.29517727 |
39 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.24443544 |
40 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.21165288 |
41 | Nicotine addiction_Homo sapiens_hsa05033 | 1.20411418 |
42 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.16952855 |
43 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.15304765 |
44 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.12788761 |
45 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.12311672 |
46 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.06167899 |
47 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.06138322 |
48 | * Nitrogen metabolism_Homo sapiens_hsa00910 | 1.05127935 |
49 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.03676506 |
50 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.03467359 |
51 | Peroxisome_Homo sapiens_hsa04146 | 1.02264110 |
52 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.01077569 |
53 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.95835028 |
54 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.95594127 |
55 | Purine metabolism_Homo sapiens_hsa00230 | 0.95299596 |
56 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.93207857 |
57 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.89316051 |
58 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.88569228 |
59 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.85383510 |
60 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.83794972 |
61 | Metabolic pathways_Homo sapiens_hsa01100 | 0.78331110 |
62 | Retinol metabolism_Homo sapiens_hsa00830 | 0.77578793 |
63 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.75231916 |
64 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.74928924 |
65 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.74388498 |
66 | Taste transduction_Homo sapiens_hsa04742 | 0.74185940 |
67 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.73534862 |
68 | Cell cycle_Homo sapiens_hsa04110 | 0.73082263 |
69 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.70348514 |
70 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.69682338 |
71 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.69240604 |
72 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.69148441 |
73 | Sulfur relay system_Homo sapiens_hsa04122 | 0.69112885 |
74 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.69042774 |
75 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.66740845 |
76 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.66607460 |
77 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.66517510 |
78 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.64251565 |
79 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.63832899 |
80 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.63304493 |
81 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.58425142 |
82 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.57897218 |
83 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.57279870 |
84 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.55092531 |
85 | Olfactory transduction_Homo sapiens_hsa04740 | 0.53751227 |
86 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.53705842 |
87 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.52700959 |
88 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.52086046 |
89 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.48708710 |
90 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.48040277 |
91 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.46890871 |
92 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.45987023 |
93 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.45251102 |
94 | Histidine metabolism_Homo sapiens_hsa00340 | 0.43859813 |
95 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.43636886 |
96 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.42585955 |
97 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.41703198 |
98 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.40433483 |
99 | Axon guidance_Homo sapiens_hsa04360 | 0.40113623 |
100 | Morphine addiction_Homo sapiens_hsa05032 | 0.39717542 |