Rank | Gene Set | Z-score |
---|---|---|
1 | behavioral response to nicotine (GO:0035095) | 5.64231907 |
2 | DNA deamination (GO:0045006) | 4.83333950 |
3 | response to pheromone (GO:0019236) | 4.56873267 |
4 | nucleobase catabolic process (GO:0046113) | 4.51560243 |
5 | fucose catabolic process (GO:0019317) | 4.31031660 |
6 | L-fucose metabolic process (GO:0042354) | 4.31031660 |
7 | L-fucose catabolic process (GO:0042355) | 4.31031660 |
8 | cellular ketone body metabolic process (GO:0046950) | 3.63473022 |
9 | piRNA metabolic process (GO:0034587) | 3.58897015 |
10 | axoneme assembly (GO:0035082) | 3.54355122 |
11 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.52757594 |
12 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.50896197 |
13 | respiratory chain complex IV assembly (GO:0008535) | 3.46800225 |
14 | platelet dense granule organization (GO:0060155) | 3.45246909 |
15 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.42650179 |
16 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 3.32336317 |
17 | multicellular organism reproduction (GO:0032504) | 3.30599462 |
18 | ketone body metabolic process (GO:1902224) | 3.30477522 |
19 | indolalkylamine metabolic process (GO:0006586) | 3.27998982 |
20 | negative regulation of telomere maintenance (GO:0032205) | 3.26585759 |
21 | detection of light stimulus involved in visual perception (GO:0050908) | 3.22658246 |
22 | detection of light stimulus involved in sensory perception (GO:0050962) | 3.22658246 |
23 | tryptophan catabolic process (GO:0006569) | 3.20254654 |
24 | indole-containing compound catabolic process (GO:0042436) | 3.20254654 |
25 | indolalkylamine catabolic process (GO:0046218) | 3.20254654 |
26 | protein polyglutamylation (GO:0018095) | 3.19615498 |
27 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.13613480 |
28 | protein-cofactor linkage (GO:0018065) | 3.10403355 |
29 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.08462993 |
30 | S-adenosylmethionine metabolic process (GO:0046500) | 3.07062889 |
31 | mannosylation (GO:0097502) | 3.06870230 |
32 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.05383745 |
33 | gamma-aminobutyric acid transport (GO:0015812) | 3.02423284 |
34 | kynurenine metabolic process (GO:0070189) | 3.02278166 |
35 | neural tube formation (GO:0001841) | 3.01437498 |
36 | protein complex biogenesis (GO:0070271) | 2.98691534 |
37 | cytochrome complex assembly (GO:0017004) | 2.96137325 |
38 | protein K11-linked deubiquitination (GO:0035871) | 2.95093755 |
39 | adaptation of signaling pathway (GO:0023058) | 2.93110518 |
40 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.92773193 |
41 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.92773193 |
42 | NADH dehydrogenase complex assembly (GO:0010257) | 2.92773193 |
43 | cytidine metabolic process (GO:0046087) | 2.89081097 |
44 | cytidine catabolic process (GO:0006216) | 2.89081097 |
45 | cytidine deamination (GO:0009972) | 2.89081097 |
46 | epithelial cilium movement (GO:0003351) | 2.87306140 |
47 | negative regulation of execution phase of apoptosis (GO:1900118) | 2.87224351 |
48 | kidney morphogenesis (GO:0060993) | 2.83196488 |
49 | tryptophan metabolic process (GO:0006568) | 2.82485615 |
50 | rRNA catabolic process (GO:0016075) | 2.81167894 |
51 | protein localization to cilium (GO:0061512) | 2.80656605 |
52 | retinal cone cell development (GO:0046549) | 2.80392796 |
53 | hair cycle (GO:0042633) | 2.75741843 |
54 | molting cycle (GO:0042303) | 2.75741843 |
55 | phosphatidylethanolamine acyl-chain remodeling (GO:0036152) | 2.69551799 |
56 | phosphatidylserine acyl-chain remodeling (GO:0036150) | 2.69336095 |
57 | reflex (GO:0060004) | 2.68193042 |
58 | regulation of cilium movement (GO:0003352) | 2.67769866 |
59 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.67076291 |
60 | photoreceptor cell maintenance (GO:0045494) | 2.66832224 |
61 | indole-containing compound metabolic process (GO:0042430) | 2.64600886 |
62 | regulation of sequestering of triglyceride (GO:0010889) | 2.63855407 |
63 | behavioral response to ethanol (GO:0048149) | 2.63627719 |
64 | DNA methylation involved in gamete generation (GO:0043046) | 2.63122019 |
65 | somite development (GO:0061053) | 2.62454802 |
66 | protein import into peroxisome matrix (GO:0016558) | 2.61949419 |
67 | positive regulation of fatty acid transport (GO:2000193) | 2.61841062 |
68 | cilium morphogenesis (GO:0060271) | 2.60759872 |
69 | primary amino compound metabolic process (GO:1901160) | 2.60523617 |
70 | cornea development in camera-type eye (GO:0061303) | 2.59634413 |
71 | oligosaccharide biosynthetic process (GO:0009312) | 2.59440929 |
72 | neuronal action potential (GO:0019228) | 2.58756202 |
73 | amine catabolic process (GO:0009310) | 2.57232892 |
74 | cellular biogenic amine catabolic process (GO:0042402) | 2.57232892 |
75 | pyrimidine nucleobase catabolic process (GO:0006208) | 2.54830596 |
76 | ubiquinone biosynthetic process (GO:0006744) | 2.54316307 |
77 | synaptic transmission, cholinergic (GO:0007271) | 2.52594479 |
78 | regulation of endothelial cell differentiation (GO:0045601) | 2.52279274 |
79 | adenosine metabolic process (GO:0046085) | 2.51203334 |
80 | negative regulation of mast cell activation (GO:0033004) | 2.49618791 |
81 | cAMP catabolic process (GO:0006198) | 2.49291208 |
82 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 2.45028244 |
83 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.44426105 |
84 | L-methionine salvage (GO:0071267) | 2.43790292 |
85 | L-methionine biosynthetic process (GO:0071265) | 2.43790292 |
86 | amino acid salvage (GO:0043102) | 2.43790292 |
87 | regulation of action potential (GO:0098900) | 2.43361094 |
88 | regulation of hexokinase activity (GO:1903299) | 2.42728458 |
89 | regulation of glucokinase activity (GO:0033131) | 2.42728458 |
90 | nonmotile primary cilium assembly (GO:0035058) | 2.42507359 |
91 | photoreceptor cell development (GO:0042461) | 2.42412316 |
92 | positive regulation of prostaglandin secretion (GO:0032308) | 2.40929932 |
93 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 2.40914560 |
94 | regulation of rhodopsin mediated signaling pathway (GO:0022400) | 2.40515271 |
95 | auditory receptor cell stereocilium organization (GO:0060088) | 2.40064813 |
96 | inositol phosphate catabolic process (GO:0071545) | 2.37494528 |
97 | rhodopsin mediated signaling pathway (GO:0016056) | 2.37156307 |
98 | ubiquinone metabolic process (GO:0006743) | 2.36796160 |
99 | head development (GO:0060322) | 2.35720494 |
100 | phosphatidylcholine acyl-chain remodeling (GO:0036151) | 2.35405717 |
Rank | Gene Set | Z-score |
---|---|---|
1 | ZNF274_21170338_ChIP-Seq_K562_Hela | 4.02849332 |
2 | VDR_22108803_ChIP-Seq_LS180_Human | 3.30424217 |
3 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.82762628 |
4 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.56983095 |
5 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.43610806 |
6 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.42120824 |
7 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.37580460 |
8 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.24289155 |
9 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.20174760 |
10 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.19934496 |
11 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 2.03480032 |
12 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.95433488 |
13 | FUS_26573619_Chip-Seq_HEK293_Human | 1.95391418 |
14 | EWS_26573619_Chip-Seq_HEK293_Human | 1.95295113 |
15 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.88891281 |
16 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.86797928 |
17 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.84306135 |
18 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.83541977 |
19 | P300_19829295_ChIP-Seq_ESCs_Human | 1.81696751 |
20 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.79260794 |
21 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.77190362 |
22 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.75825403 |
23 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.71163114 |
24 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.70747585 |
25 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.69347023 |
26 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.62364294 |
27 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.58706642 |
28 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.58706642 |
29 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.54084496 |
30 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.53865548 |
31 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.52412458 |
32 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.52204108 |
33 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.48824247 |
34 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.47058955 |
35 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.46400380 |
36 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.46400380 |
37 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.41777612 |
38 | AR_25329375_ChIP-Seq_VCAP_Human | 1.41171370 |
39 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.40441854 |
40 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.40441854 |
41 | * STAT3_23295773_ChIP-Seq_U87_Human | 1.39525099 |
42 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.38276450 |
43 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.38208917 |
44 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.38124849 |
45 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.37838944 |
46 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.37838944 |
47 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.37460208 |
48 | TCF4_23295773_ChIP-Seq_U87_Human | 1.35692686 |
49 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.34831613 |
50 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.34641675 |
51 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.33236360 |
52 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.33060781 |
53 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.32667623 |
54 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.31642626 |
55 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.30191946 |
56 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.27693893 |
57 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.26853122 |
58 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.26654493 |
59 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.25443076 |
60 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.25289570 |
61 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.25282960 |
62 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.25260065 |
63 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.24997705 |
64 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.24009845 |
65 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.23504791 |
66 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.23263658 |
67 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.23120754 |
68 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.20829585 |
69 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.20693772 |
70 | * AR_20517297_ChIP-Seq_VCAP_Human | 1.20410237 |
71 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.19762623 |
72 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.19758670 |
73 | * NCOR_22424771_ChIP-Seq_293T_Human | 1.19283813 |
74 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.18600194 |
75 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.16398064 |
76 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.16189412 |
77 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.15181192 |
78 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.14960959 |
79 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.13857931 |
80 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.13784249 |
81 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.13651780 |
82 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.11349800 |
83 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.10902778 |
84 | GATA3_26560356_Chip-Seq_TH2_Human | 1.10202292 |
85 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.09549443 |
86 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.06629963 |
87 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.06329426 |
88 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.06252275 |
89 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.05198504 |
90 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.04506244 |
91 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.01478853 |
92 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.01330355 |
93 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.01106509 |
94 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.01063570 |
95 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.00219750 |
96 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.99794191 |
97 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.99275697 |
98 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.99258992 |
99 | * PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.98482615 |
100 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.98291926 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0000569_abnormal_digit_pigmentation | 3.19394110 |
2 | MP0008877_abnormal_DNA_methylation | 3.19210446 |
3 | MP0002138_abnormal_hepatobiliary_system | 2.75389127 |
4 | MP0001881_abnormal_mammary_gland | 2.59524572 |
5 | MP0003195_calcinosis | 2.58909397 |
6 | MP0002102_abnormal_ear_morphology | 2.54522303 |
7 | MP0005645_abnormal_hypothalamus_physiol | 2.42143492 |
8 | MP0005551_abnormal_eye_electrophysiolog | 2.35405149 |
9 | MP0005646_abnormal_pituitary_gland | 2.15763123 |
10 | MP0004885_abnormal_endolymph | 2.12535906 |
11 | MP0003787_abnormal_imprinting | 2.12038284 |
12 | MP0006072_abnormal_retinal_apoptosis | 2.07421589 |
13 | MP0001968_abnormal_touch/_nociception | 2.07301311 |
14 | MP0004043_abnormal_pH_regulation | 2.04795349 |
15 | MP0003011_delayed_dark_adaptation | 1.98852047 |
16 | MP0005075_abnormal_melanosome_morpholog | 1.95237616 |
17 | MP0008875_abnormal_xenobiotic_pharmacok | 1.85000850 |
18 | MP0008872_abnormal_physiological_respon | 1.81569787 |
19 | MP0002638_abnormal_pupillary_reflex | 1.81242673 |
20 | MP0000372_irregular_coat_pigmentation | 1.79044823 |
21 | MP0002837_dystrophic_cardiac_calcinosis | 1.77066850 |
22 | MP0001986_abnormal_taste_sensitivity | 1.76797590 |
23 | MP0004147_increased_porphyrin_level | 1.75194392 |
24 | MP0002876_abnormal_thyroid_physiology | 1.70819494 |
25 | MP0005174_abnormal_tail_pigmentation | 1.70323952 |
26 | MP0004142_abnormal_muscle_tone | 1.69645610 |
27 | MP0005253_abnormal_eye_physiology | 1.68092339 |
28 | MP0009745_abnormal_behavioral_response | 1.63340378 |
29 | MP0001984_abnormal_olfaction | 1.62293129 |
30 | MP0001501_abnormal_sleep_pattern | 1.60531614 |
31 | MP0003718_maternal_effect | 1.60092669 |
32 | MP0004742_abnormal_vestibular_system | 1.59451556 |
33 | MP0005084_abnormal_gallbladder_morpholo | 1.55334528 |
34 | MP0002928_abnormal_bile_duct | 1.51255728 |
35 | MP0000647_abnormal_sebaceous_gland | 1.51108252 |
36 | MP0009046_muscle_twitch | 1.50656308 |
37 | MP0002736_abnormal_nociception_after | 1.50157749 |
38 | MP0001485_abnormal_pinna_reflex | 1.47197229 |
39 | MP0000015_abnormal_ear_pigmentation | 1.45507829 |
40 | MP0002272_abnormal_nervous_system | 1.43607711 |
41 | MP0002653_abnormal_ependyma_morphology | 1.42642331 |
42 | MP0000427_abnormal_hair_cycle | 1.41094328 |
43 | MP0003880_abnormal_central_pattern | 1.37981719 |
44 | MP0003646_muscle_fatigue | 1.36538541 |
45 | MP0006292_abnormal_olfactory_placode | 1.31165480 |
46 | MP0000631_abnormal_neuroendocrine_gland | 1.28609358 |
47 | MP0001486_abnormal_startle_reflex | 1.26960918 |
48 | MP0005671_abnormal_response_to | 1.26946768 |
49 | MP0002095_abnormal_skin_pigmentation | 1.25086246 |
50 | MP0002163_abnormal_gland_morphology | 1.24678589 |
51 | MP0005410_abnormal_fertilization | 1.21415209 |
52 | MP0004133_heterotaxia | 1.17540967 |
53 | MP0006276_abnormal_autonomic_nervous | 1.16647747 |
54 | MP0010386_abnormal_urinary_bladder | 1.12309999 |
55 | MP0005377_hearing/vestibular/ear_phenot | 1.09598231 |
56 | MP0003878_abnormal_ear_physiology | 1.09598231 |
57 | MP0003252_abnormal_bile_duct | 1.07928654 |
58 | MP0005332_abnormal_amino_acid | 1.06179013 |
59 | MP0002938_white_spotting | 1.05798149 |
60 | MP0002572_abnormal_emotion/affect_behav | 1.04343051 |
61 | MP0002064_seizures | 1.03938115 |
62 | MP0004924_abnormal_behavior | 1.02745616 |
63 | MP0005386_behavior/neurological_phenoty | 1.02745616 |
64 | MP0005379_endocrine/exocrine_gland_phen | 1.02525864 |
65 | MP0004145_abnormal_muscle_electrophysio | 1.02034255 |
66 | MP0001970_abnormal_pain_threshold | 1.01450628 |
67 | MP0000383_abnormal_hair_follicle | 0.99934198 |
68 | MP0005389_reproductive_system_phenotype | 0.99234125 |
69 | MP0002733_abnormal_thermal_nociception | 0.99102005 |
70 | MP0002557_abnormal_social/conspecific_i | 0.98637144 |
71 | MP0005085_abnormal_gallbladder_physiolo | 0.97658875 |
72 | MP0002693_abnormal_pancreas_physiology | 0.95513217 |
73 | MP0001919_abnormal_reproductive_system | 0.94780714 |
74 | MP0002735_abnormal_chemical_nociception | 0.94636459 |
75 | MP0002067_abnormal_sensory_capabilities | 0.93949691 |
76 | MP0009764_decreased_sensitivity_to | 0.91420996 |
77 | MP0005195_abnormal_posterior_eye | 0.85285953 |
78 | MP0001764_abnormal_homeostasis | 0.84994652 |
79 | MP0002254_reproductive_system_inflammat | 0.84143449 |
80 | MP0008789_abnormal_olfactory_epithelium | 0.81822508 |
81 | MP0003136_yellow_coat_color | 0.80719828 |
82 | MP0004130_abnormal_muscle_cell | 0.80514791 |
83 | MP0002063_abnormal_learning/memory/cond | 0.80345068 |
84 | MP0000230_abnormal_systemic_arterial | 0.79333722 |
85 | MP0000026_abnormal_inner_ear | 0.78541682 |
86 | MP0002234_abnormal_pharynx_morphology | 0.77677212 |
87 | MP0005083_abnormal_biliary_tract | 0.76699032 |
88 | MP0002277_abnormal_respiratory_mucosa | 0.75223719 |
89 | MP0002229_neurodegeneration | 0.75138049 |
90 | MP0001905_abnormal_dopamine_level | 0.74928045 |
91 | MP0003283_abnormal_digestive_organ | 0.74454321 |
92 | MP0000613_abnormal_salivary_gland | 0.74400875 |
93 | MP0010329_abnormal_lipoprotein_level | 0.73980962 |
94 | MP0002148_abnormal_hypersensitivity_rea | 0.73922668 |
95 | MP0008995_early_reproductive_senescence | 0.73693782 |
96 | MP0001324_abnormal_eye_pigmentation | 0.73607168 |
97 | MP0003635_abnormal_synaptic_transmissio | 0.72472085 |
98 | MP0005636_abnormal_mineral_homeostasis | 0.71631871 |
99 | MP0003698_abnormal_male_reproductive | 0.70863694 |
100 | MP0002752_abnormal_somatic_nervous | 0.70675851 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Pancreatic cysts (HP:0001737) | 4.54151819 |
2 | Congenital stationary night blindness (HP:0007642) | 4.23649454 |
3 | Abnormality of midbrain morphology (HP:0002418) | 4.09607862 |
4 | Molar tooth sign on MRI (HP:0002419) | 4.09607862 |
5 | Pancreatic fibrosis (HP:0100732) | 4.00441183 |
6 | Type II lissencephaly (HP:0007260) | 3.96570527 |
7 | True hermaphroditism (HP:0010459) | 3.87048065 |
8 | Nephronophthisis (HP:0000090) | 3.61102502 |
9 | Abnormality of the renal cortex (HP:0011035) | 3.58059559 |
10 | Abnormality of the renal medulla (HP:0100957) | 3.37874162 |
11 | Abolished electroretinogram (ERG) (HP:0000550) | 2.97912665 |
12 | Congenital, generalized hypertrichosis (HP:0004540) | 2.92864077 |
13 | Medial flaring of the eyebrow (HP:0010747) | 2.82532286 |
14 | Fair hair (HP:0002286) | 2.81814915 |
15 | Tubular atrophy (HP:0000092) | 2.76116649 |
16 | Inability to walk (HP:0002540) | 2.74893333 |
17 | Attenuation of retinal blood vessels (HP:0007843) | 2.71317978 |
18 | Decreased circulating renin level (HP:0003351) | 2.68200526 |
19 | Cystic liver disease (HP:0006706) | 2.67815743 |
20 | 3-Methylglutaconic aciduria (HP:0003535) | 2.62807856 |
21 | Cerebellar dysplasia (HP:0007033) | 2.61737038 |
22 | Progressive inability to walk (HP:0002505) | 2.60065124 |
23 | Chronic hepatic failure (HP:0100626) | 2.58328718 |
24 | Hyperventilation (HP:0002883) | 2.57354162 |
25 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.57121521 |
26 | Polydipsia (HP:0001959) | 2.52891500 |
27 | Abnormal drinking behavior (HP:0030082) | 2.52891500 |
28 | Renal cortical cysts (HP:0000803) | 2.46324026 |
29 | Pendular nystagmus (HP:0012043) | 2.45657897 |
30 | Stomatitis (HP:0010280) | 2.44020073 |
31 | Furrowed tongue (HP:0000221) | 2.31987801 |
32 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.31043397 |
33 | Abnormality of alanine metabolism (HP:0010916) | 2.29121113 |
34 | Hyperalaninemia (HP:0003348) | 2.29121113 |
35 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.29121113 |
36 | Abnormal biliary tract physiology (HP:0012439) | 2.27874636 |
37 | Bile duct proliferation (HP:0001408) | 2.27874636 |
38 | Increased corneal curvature (HP:0100692) | 2.27034145 |
39 | Keratoconus (HP:0000563) | 2.27034145 |
40 | Lissencephaly (HP:0001339) | 2.24435432 |
41 | Generalized hypopigmentation of hair (HP:0011358) | 2.22039577 |
42 | Concave nail (HP:0001598) | 2.21239238 |
43 | Large for gestational age (HP:0001520) | 2.21134104 |
44 | Gaze-evoked nystagmus (HP:0000640) | 2.19856074 |
45 | Acute necrotizing encephalopathy (HP:0006965) | 2.18493420 |
46 | Sclerocornea (HP:0000647) | 2.18325313 |
47 | Stomach cancer (HP:0012126) | 2.17256011 |
48 | Polyuria (HP:0000103) | 2.17027754 |
49 | Pachygyria (HP:0001302) | 2.16743699 |
50 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.10665704 |
51 | Mitochondrial inheritance (HP:0001427) | 2.09725971 |
52 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.06844378 |
53 | Absent/shortened dynein arms (HP:0200106) | 2.06844378 |
54 | Methylmalonic acidemia (HP:0002912) | 2.06840383 |
55 | Retinal dysplasia (HP:0007973) | 2.06158616 |
56 | Progressive macrocephaly (HP:0004481) | 2.06002298 |
57 | Increased CSF lactate (HP:0002490) | 2.02667701 |
58 | Gait imbalance (HP:0002141) | 1.99915368 |
59 | Congenital hepatic fibrosis (HP:0002612) | 1.98533393 |
60 | Severe muscular hypotonia (HP:0006829) | 1.96445757 |
61 | Male pseudohermaphroditism (HP:0000037) | 1.92519343 |
62 | Congenital primary aphakia (HP:0007707) | 1.92358135 |
63 | Acute encephalopathy (HP:0006846) | 1.91857644 |
64 | Optic disc pallor (HP:0000543) | 1.87499241 |
65 | Hypokalemic alkalosis (HP:0001949) | 1.87299221 |
66 | IgG deficiency (HP:0004315) | 1.86624405 |
67 | Absent speech (HP:0001344) | 1.86446210 |
68 | Amelogenesis imperfecta (HP:0000705) | 1.84662176 |
69 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.84531913 |
70 | Abnormality of the pons (HP:0007361) | 1.84171284 |
71 | Hypothermia (HP:0002045) | 1.83714610 |
72 | Postaxial foot polydactyly (HP:0001830) | 1.82742344 |
73 | Anencephaly (HP:0002323) | 1.81854658 |
74 | Nephrogenic diabetes insipidus (HP:0009806) | 1.81218085 |
75 | Hemiparesis (HP:0001269) | 1.80729662 |
76 | Broad-based gait (HP:0002136) | 1.80502634 |
77 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.80200764 |
78 | Febrile seizures (HP:0002373) | 1.79161716 |
79 | Type I transferrin isoform profile (HP:0003642) | 1.78789222 |
80 | Congenital sensorineural hearing impairment (HP:0008527) | 1.78683558 |
81 | Decreased central vision (HP:0007663) | 1.78449603 |
82 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.77086692 |
83 | Tubulointerstitial fibrosis (HP:0005576) | 1.76969765 |
84 | Ketosis (HP:0001946) | 1.76101558 |
85 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.74198403 |
86 | Hypoplasia of the fovea (HP:0007750) | 1.73907427 |
87 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 1.73907427 |
88 | Abnormal urine output (HP:0012590) | 1.73315002 |
89 | Methylmalonic aciduria (HP:0012120) | 1.72760494 |
90 | Agitation (HP:0000713) | 1.71359361 |
91 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.70765964 |
92 | Hypoproteinemia (HP:0003075) | 1.70469800 |
93 | Progressive cerebellar ataxia (HP:0002073) | 1.69597122 |
94 | Optic nerve hypoplasia (HP:0000609) | 1.69586566 |
95 | Thyroiditis (HP:0100646) | 1.69480357 |
96 | Hypomagnesemia (HP:0002917) | 1.69028894 |
97 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.68781275 |
98 | Ketoacidosis (HP:0001993) | 1.67481625 |
99 | Severe visual impairment (HP:0001141) | 1.67397448 |
100 | Abnormality of renal excretion (HP:0011036) | 1.67382173 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FRK | 5.08742174 |
2 | ADRBK2 | 3.81665237 |
3 | BMPR1B | 3.11678377 |
4 | TAOK3 | 2.93983438 |
5 | MAP4K2 | 2.66030554 |
6 | NUAK1 | 2.60181777 |
7 | GRK1 | 2.54995124 |
8 | TXK | 2.54167356 |
9 | WNK4 | 2.38016795 |
10 | WNK3 | 2.32191465 |
11 | ZAK | 2.22119285 |
12 | PINK1 | 2.10687664 |
13 | ACVR1B | 2.09571738 |
14 | MAPK13 | 1.88479529 |
15 | MAPKAPK3 | 1.70947713 |
16 | INSRR | 1.66928354 |
17 | TLK1 | 1.64338294 |
18 | OXSR1 | 1.63584730 |
19 | STK39 | 1.53149345 |
20 | TRIM28 | 1.38619677 |
21 | MAP3K4 | 1.37151726 |
22 | BCKDK | 1.36489075 |
23 | MKNK2 | 1.34243960 |
24 | NTRK3 | 1.32607723 |
25 | CAMKK2 | 1.29391903 |
26 | TGFBR1 | 1.27484333 |
27 | CASK | 1.22231376 |
28 | ADRBK1 | 1.16288984 |
29 | KIT | 1.10951708 |
30 | DYRK2 | 1.10246528 |
31 | PAK3 | 1.07572610 |
32 | DAPK2 | 1.05784406 |
33 | MAP2K6 | 1.02496828 |
34 | PNCK | 1.00020695 |
35 | MARK1 | 0.97024103 |
36 | PTK2B | 0.96942000 |
37 | PRKCE | 0.92024966 |
38 | VRK1 | 0.89465875 |
39 | MAPK15 | 0.89354590 |
40 | ERBB3 | 0.87132899 |
41 | PHKG1 | 0.86613099 |
42 | PHKG2 | 0.86613099 |
43 | IKBKB | 0.86289668 |
44 | PRKCG | 0.84973705 |
45 | MAPKAPK5 | 0.84148767 |
46 | BCR | 0.81406934 |
47 | SYK | 0.78676645 |
48 | TEC | 0.77833467 |
49 | TIE1 | 0.75232829 |
50 | PLK2 | 0.73850065 |
51 | ITK | 0.71957015 |
52 | BRSK2 | 0.71689429 |
53 | PRKCQ | 0.71432036 |
54 | IRAK1 | 0.70228234 |
55 | FGFR2 | 0.69327704 |
56 | GRK7 | 0.68937484 |
57 | CSNK1G1 | 0.65194003 |
58 | MAP2K7 | 0.62204107 |
59 | CSNK1G3 | 0.61451521 |
60 | CSNK1G2 | 0.61440535 |
61 | MAP2K2 | 0.56586468 |
62 | PIK3CA | 0.56390526 |
63 | MKNK1 | 0.54624621 |
64 | CDK8 | 0.52235806 |
65 | STK3 | 0.51723349 |
66 | CSNK1A1 | 0.51308333 |
67 | STK38L | 0.51197930 |
68 | MUSK | 0.50519655 |
69 | IGF1R | 0.49464061 |
70 | MST4 | 0.47538701 |
71 | STK11 | 0.47328152 |
72 | GRK5 | 0.46176907 |
73 | RPS6KA5 | 0.45561442 |
74 | TNIK | 0.44845183 |
75 | EIF2AK3 | 0.43660658 |
76 | LCK | 0.43473080 |
77 | CSNK1A1L | 0.43393353 |
78 | CHUK | 0.43328667 |
79 | CAMK2A | 0.43108336 |
80 | PRKACA | 0.42904356 |
81 | LYN | 0.42682968 |
82 | IKBKE | 0.41868943 |
83 | MAP4K1 | 0.41090565 |
84 | PIK3CG | 0.40952418 |
85 | GRK6 | 0.38775690 |
86 | PRKAA1 | 0.36535629 |
87 | PRKCI | 0.36529054 |
88 | TNK2 | 0.36018076 |
89 | JAK3 | 0.35719427 |
90 | EPHA3 | 0.35700090 |
91 | TAF1 | 0.35250990 |
92 | FES | 0.34873923 |
93 | PRKCA | 0.34856483 |
94 | TRPM7 | 0.34583819 |
95 | PLK3 | 0.34154748 |
96 | TSSK6 | 0.32864795 |
97 | CAMK1 | 0.32619607 |
98 | ABL1 | 0.31900229 |
99 | CSNK1D | 0.31686259 |
100 | PRKCZ | 0.31317455 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Caffeine metabolism_Homo sapiens_hsa00232 | 5.72384970 |
2 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 3.09431713 |
3 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.83002790 |
4 | Phototransduction_Homo sapiens_hsa04744 | 2.55126563 |
5 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.37139926 |
6 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 2.15857382 |
7 | Ether lipid metabolism_Homo sapiens_hsa00565 | 2.12221841 |
8 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.08775787 |
9 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.03089096 |
10 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.95740376 |
11 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.95180724 |
12 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.92204023 |
13 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.85086442 |
14 | Peroxisome_Homo sapiens_hsa04146 | 1.76897099 |
15 | * Nitrogen metabolism_Homo sapiens_hsa00910 | 1.67514481 |
16 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.66933828 |
17 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.60119232 |
18 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.55525582 |
19 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.55126676 |
20 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.53630918 |
21 | Protein export_Homo sapiens_hsa03060 | 1.49742268 |
22 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.48056771 |
23 | Nicotine addiction_Homo sapiens_hsa05033 | 1.46599058 |
24 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.41297817 |
25 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.32685727 |
26 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.32152401 |
27 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.30841716 |
28 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.25684811 |
29 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.24531570 |
30 | RNA polymerase_Homo sapiens_hsa03020 | 1.23975473 |
31 | Asthma_Homo sapiens_hsa05310 | 1.21920231 |
32 | Parkinsons disease_Homo sapiens_hsa05012 | 1.21417582 |
33 | Olfactory transduction_Homo sapiens_hsa04740 | 1.14351566 |
34 | Morphine addiction_Homo sapiens_hsa05032 | 1.11978128 |
35 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.11895447 |
36 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.10375124 |
37 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.10089986 |
38 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.09222425 |
39 | Allograft rejection_Homo sapiens_hsa05330 | 1.08039228 |
40 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.06931045 |
41 | Homologous recombination_Homo sapiens_hsa03440 | 1.05484745 |
42 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.05382486 |
43 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.05231222 |
44 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.04046329 |
45 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.02312368 |
46 | RNA degradation_Homo sapiens_hsa03018 | 1.00488506 |
47 | Taste transduction_Homo sapiens_hsa04742 | 1.00249694 |
48 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.00122620 |
49 | Basal transcription factors_Homo sapiens_hsa03022 | 0.99992093 |
50 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.89767857 |
51 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.88749013 |
52 | Histidine metabolism_Homo sapiens_hsa00340 | 0.88278555 |
53 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.88043457 |
54 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.86898836 |
55 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.82417784 |
56 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.81663007 |
57 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.78814128 |
58 | Proteasome_Homo sapiens_hsa03050 | 0.78335320 |
59 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.77251188 |
60 | ABC transporters_Homo sapiens_hsa02010 | 0.76561147 |
61 | Insulin secretion_Homo sapiens_hsa04911 | 0.75503020 |
62 | Alzheimers disease_Homo sapiens_hsa05010 | 0.74951663 |
63 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.73959629 |
64 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.72935900 |
65 | Retinol metabolism_Homo sapiens_hsa00830 | 0.72918809 |
66 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.72405408 |
67 | Circadian entrainment_Homo sapiens_hsa04713 | 0.70737197 |
68 | GABAergic synapse_Homo sapiens_hsa04727 | 0.70482084 |
69 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.70455909 |
70 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.70241834 |
71 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.68428433 |
72 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.68116273 |
73 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.66454092 |
74 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.65731326 |
75 | Huntingtons disease_Homo sapiens_hsa05016 | 0.65520703 |
76 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.64275657 |
77 | Salivary secretion_Homo sapiens_hsa04970 | 0.61253829 |
78 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.60931010 |
79 | Purine metabolism_Homo sapiens_hsa00230 | 0.59125300 |
80 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.57687454 |
81 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.56644498 |
82 | Metabolic pathways_Homo sapiens_hsa01100 | 0.54806541 |
83 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.54250689 |
84 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.51809622 |
85 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.51796254 |
86 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.51184316 |
87 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.44904028 |
88 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.41880184 |
89 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.41181150 |
90 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.41130686 |
91 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.39698155 |
92 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.38254174 |
93 | Circadian rhythm_Homo sapiens_hsa04710 | 0.35459961 |
94 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.33819919 |
95 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.33379123 |
96 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.32991254 |
97 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.32450494 |
98 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.32103316 |
99 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.31968656 |
100 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.31473776 |