CAAP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of transcription elongation from RNA polymerase II promoter (GO:0032968)4.56086932
2DNA replication initiation (GO:0006270)4.50157196
3apoptotic DNA fragmentation (GO:0006309)4.47421329
4translational termination (GO:0006415)4.43543219
5viral transcription (GO:0019083)4.42936542
6maturation of SSU-rRNA (GO:0030490)4.31339367
7DNA unwinding involved in DNA replication (GO:0006268)4.18665513
8regulation of double-strand break repair via homologous recombination (GO:0010569)4.17615675
9ribosomal small subunit biogenesis (GO:0042274)4.17426422
10folic acid-containing compound biosynthetic process (GO:0009396)4.10552244
11ribosomal small subunit assembly (GO:0000028)4.04094163
12purine nucleobase biosynthetic process (GO:0009113)4.03369967
13telomere maintenance via semi-conservative replication (GO:0032201)3.93613428
147-methylguanosine mRNA capping (GO:0006370)3.91669695
15DNA strand elongation involved in DNA replication (GO:0006271)3.89356103
16nucleobase biosynthetic process (GO:0046112)3.89051257
17mitotic metaphase plate congression (GO:0007080)3.88513535
18transcription from mitochondrial promoter (GO:0006390)3.81936804
19translational elongation (GO:0006414)3.79355092
20RNA capping (GO:0036260)3.79196949
217-methylguanosine RNA capping (GO:0009452)3.79196949
22protein localization to kinetochore (GO:0034501)3.77469086
23translational initiation (GO:0006413)3.75508214
24microtubule depolymerization (GO:0007019)3.72266622
25DNA strand elongation (GO:0022616)3.71173058
26cytokinetic process (GO:0032506)3.70918348
27mitotic sister chromatid segregation (GO:0000070)3.70069304
28nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.69924152
29establishment of viral latency (GO:0019043)3.68495099
30positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.67315582
31positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.67315582
32positive regulation of mitotic sister chromatid separation (GO:1901970)3.67315582
33SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.66848900
34protein complex localization (GO:0031503)3.65471437
35CENP-A containing nucleosome assembly (GO:0034080)3.63322027
36mitotic cytokinesis (GO:0000281)3.61298370
37ribonucleoprotein complex biogenesis (GO:0022613)3.61006784
38ribosomal large subunit biogenesis (GO:0042273)3.60554620
39chromatin remodeling at centromere (GO:0031055)3.60448334
40cotranslational protein targeting to membrane (GO:0006613)3.60288839
41nuclear pore complex assembly (GO:0051292)3.59889930
42rRNA modification (GO:0000154)3.59022813
43rRNA processing (GO:0006364)3.58974972
44protein targeting to ER (GO:0045047)3.58159059
45rRNA methylation (GO:0031167)3.57578685
46nuclear pore organization (GO:0006999)3.55892420
47telomere maintenance via recombination (GO:0000722)3.55589555
48formation of translation preinitiation complex (GO:0001731)3.54862878
49cytoskeleton-dependent cytokinesis (GO:0061640)3.54616353
50DNA replication-independent nucleosome organization (GO:0034724)3.53293609
51DNA replication-independent nucleosome assembly (GO:0006336)3.53293609
52sister chromatid segregation (GO:0000819)3.51064256
53DNA ligation (GO:0006266)3.50824181
54regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.50144936
55rRNA metabolic process (GO:0016072)3.48270947
56DNA deamination (GO:0045006)3.48121097
57regulation of chromosome segregation (GO:0051983)3.47123597
58DNA replication-dependent nucleosome organization (GO:0034723)3.46875614
59DNA replication-dependent nucleosome assembly (GO:0006335)3.46875614
60establishment of protein localization to endoplasmic reticulum (GO:0072599)3.43534855
61regulation of centriole replication (GO:0046599)3.42089680
62cellular protein complex disassembly (GO:0043624)3.41441164
63mitotic recombination (GO:0006312)3.40078664
64DNA replication checkpoint (GO:0000076)3.39907667
65ribosome biogenesis (GO:0042254)3.39630110
66negative regulation of DNA-dependent DNA replication (GO:2000104)3.36449354
67positive regulation of DNA-templated transcription, elongation (GO:0032786)3.35400870
68protein localization to endoplasmic reticulum (GO:0070972)3.35102663
69metaphase plate congression (GO:0051310)3.34895789
70proteasome assembly (GO:0043248)3.32234912
71ribosome assembly (GO:0042255)3.31557493
72viral life cycle (GO:0019058)3.29482287
73protein localization to chromosome, centromeric region (GO:0071459)3.28705081
74pseudouridine synthesis (GO:0001522)3.23024142
75protein localization to chromosome (GO:0034502)3.20583479
76double-strand break repair via nonhomologous end joining (GO:0006303)3.19668573
77non-recombinational repair (GO:0000726)3.19668573
78spindle checkpoint (GO:0031577)3.19403124
79mitotic spindle checkpoint (GO:0071174)3.18935091
80replication fork processing (GO:0031297)3.18428263
81negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.18369801
82negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.18369801
83negative regulation of mitotic sister chromatid segregation (GO:0033048)3.18369801
84negative regulation of mitotic sister chromatid separation (GO:2000816)3.18369801
85negative regulation of sister chromatid segregation (GO:0033046)3.18369801
86negative regulation of chromosome segregation (GO:0051985)3.16115764
87regulation of helicase activity (GO:0051095)3.13640880
88establishment of protein localization to mitochondrial membrane (GO:0090151)3.13460988
89IMP biosynthetic process (GO:0006188)3.12309439
90nucleotide-excision repair, DNA gap filling (GO:0006297)3.09871015
91histone exchange (GO:0043486)3.09110005
92regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.07147220
93regulation of mitotic metaphase/anaphase transition (GO:0030071)3.07147220
94meiotic chromosome segregation (GO:0045132)3.05788859
95regulation of histone H3-K9 methylation (GO:0051570)3.05309550
96regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.03999700
97protein complex disassembly (GO:0043241)3.02822302
98nuclear-transcribed mRNA catabolic process (GO:0000956)3.01189566
99pore complex assembly (GO:0046931)3.00032235
100establishment of integrated proviral latency (GO:0075713)2.98987732
101telomere maintenance via telomere lengthening (GO:0010833)2.98644983
102cellular protein complex localization (GO:0034629)2.98639751
103mitotic nuclear envelope disassembly (GO:0007077)2.97593448
104kinetochore organization (GO:0051383)2.97352176
105transcription elongation from RNA polymerase II promoter (GO:0006368)2.96644877
106protein K6-linked ubiquitination (GO:0085020)2.96624312
107polyamine biosynthetic process (GO:0006596)2.96335200
108DNA double-strand break processing (GO:0000729)2.95883241
109mitotic chromosome condensation (GO:0007076)2.95211710
110mitotic spindle assembly checkpoint (GO:0007094)2.93555502
111protein neddylation (GO:0045116)2.91738291
112IMP metabolic process (GO:0046040)2.91545745
113mitochondrial RNA metabolic process (GO:0000959)2.91505888
114positive regulation of chromosome segregation (GO:0051984)2.90282497
115regulation of mitotic sister chromatid separation (GO:0010965)2.90238109
116regulation of mitotic sister chromatid segregation (GO:0033047)2.90238109
117regulation of sister chromatid segregation (GO:0033045)2.90238109
118transcription elongation from RNA polymerase I promoter (GO:0006362)2.89935234
119positive regulation of Rho protein signal transduction (GO:0035025)2.89595070
120histone mRNA metabolic process (GO:0008334)2.89457819
121spindle assembly checkpoint (GO:0071173)2.89411312
122RNA catabolic process (GO:0006401)2.88726694
123macromolecular complex disassembly (GO:0032984)2.88310550
124N-terminal protein amino acid acetylation (GO:0006474)2.88106928
125mRNA catabolic process (GO:0006402)2.87065495
126DNA topological change (GO:0006265)2.86556460
127regulation of transcription elongation from RNA polymerase II promoter (GO:0034243)2.85763743
128chromatin assembly or disassembly (GO:0006333)2.85277015
129UTP biosynthetic process (GO:0006228)2.85151981
130regulation of centrosome duplication (GO:0010824)2.84925488
131attachment of spindle microtubules to kinetochore (GO:0008608)2.83526044
132RNA-dependent DNA replication (GO:0006278)2.82369899
133mitotic sister chromatid cohesion (GO:0007064)2.81474453
134maturation of 5.8S rRNA (GO:0000460)2.79820086
135spliceosomal complex assembly (GO:0000245)2.79121309
136maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.76867585
137negative regulation of RNA splicing (GO:0033119)2.76543961
138spliceosomal snRNP assembly (GO:0000387)2.76251554
139termination of RNA polymerase II transcription (GO:0006369)2.76060287
140translation (GO:0006412)2.73582946
141exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.71404655
142regulation of nuclear cell cycle DNA replication (GO:0033262)2.71367817
143nuclear envelope disassembly (GO:0051081)2.70478596
144membrane disassembly (GO:0030397)2.70478596
145regulation of centrosome cycle (GO:0046605)2.69410973
146somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.67579665
147somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.67579665
148isotype switching (GO:0045190)2.67579665
149RNA splicing, via transesterification reactions (GO:0000375)2.66647073
150folic acid metabolic process (GO:0046655)2.65462344
151establishment of chromosome localization (GO:0051303)2.62928208
152mRNA splicing, via spliceosome (GO:0000398)2.62448043
153RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.62448043
154regulation of RNA export from nucleus (GO:0046831)2.62063355
155negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.59553763
156negative regulation of histone methylation (GO:0031061)2.56777669
157pteridine-containing compound biosynthetic process (GO:0042559)2.56753721

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.62760765
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.47312005
3E2F4_17652178_ChIP-ChIP_JURKAT_Human4.18915264
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.38544788
5EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.10109747
6EST1_17652178_ChIP-ChIP_JURKAT_Human2.97629542
7GABP_17652178_ChIP-ChIP_JURKAT_Human2.93036503
8MYC_19079543_ChIP-ChIP_MESCs_Mouse2.91175499
9EGR1_19374776_ChIP-ChIP_THP-1_Human2.89735624
10MYC_19030024_ChIP-ChIP_MESCs_Mouse2.84979913
11FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.71034178
12KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.63489544
13MYC_18358816_ChIP-ChIP_MESCs_Mouse2.63105818
14VDR_23849224_ChIP-Seq_CD4+_Human2.48940373
15ETS1_20019798_ChIP-Seq_JURKAT_Human2.47433899
16CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.36012333
17NELFA_20434984_ChIP-Seq_ESCs_Mouse2.27903721
18E2F1_21310950_ChIP-Seq_MCF-7_Human2.27632378
19ELK1_19687146_ChIP-ChIP_HELA_Human2.26522616
20RBPJ_22232070_ChIP-Seq_NCS_Mouse2.24173859
21FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.22023617
22JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.20889109
23CREB1_15753290_ChIP-ChIP_HEK293T_Human2.19357713
24AR_21909140_ChIP-Seq_LNCAP_Human2.13089372
25XRN2_22483619_ChIP-Seq_HELA_Human2.09793095
26CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.09225191
27NOTCH1_21737748_ChIP-Seq_TLL_Human1.97862003
28KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.96704579
29PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.95863809
30SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.95051009
31DCP1A_22483619_ChIP-Seq_HELA_Human1.93512438
32E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.92604200
33FOXP3_21729870_ChIP-Seq_TREG_Human1.92035667
34HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.87223774
35HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.85993263
36MYCN_18555785_ChIP-Seq_MESCs_Mouse1.85544677
37TTF2_22483619_ChIP-Seq_HELA_Human1.83992120
38ELF1_17652178_ChIP-ChIP_JURKAT_Human1.83788918
39E2F1_18555785_ChIP-Seq_MESCs_Mouse1.81957915
40SALL1_21062744_ChIP-ChIP_HESCs_Human1.80894259
41MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.79197847
42SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.78508075
43TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.77213188
44MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.76610501
45FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.74667971
46HOXB4_20404135_ChIP-ChIP_EML_Mouse1.72959982
47POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.70034039
48GABP_19822575_ChIP-Seq_HepG2_Human1.67882034
49MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.64614015
50HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.64577047
51ZFX_18555785_ChIP-Seq_MESCs_Mouse1.52058543
52ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.50895705
53PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.50694763
54IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.49908960
55YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.48423116
56SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.47003288
57ERG_20887958_ChIP-Seq_HPC-7_Mouse1.44668121
58PADI4_21655091_ChIP-ChIP_MCF-7_Human1.41791380
59MYC_18940864_ChIP-ChIP_HL60_Human1.38962618
60GATA1_22025678_ChIP-Seq_K562_Human1.36572477
61ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.32499992
62THAP11_20581084_ChIP-Seq_MESCs_Mouse1.32104398
63SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.30829259
64MYC_22102868_ChIP-Seq_BL_Human1.29992841
65KDM5A_27292631_Chip-Seq_BREAST_Human1.29990949
66GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.25539445
67FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.24575900
68NANOG_18555785_ChIP-Seq_MESCs_Mouse1.22254353
69CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.19315415
70SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.16576217
71TAF15_26573619_Chip-Seq_HEK293_Human1.15866276
72SPI1_23547873_ChIP-Seq_NB4_Human1.15166265
73POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.11990277
74KLF4_18555785_ChIP-Seq_MESCs_Mouse1.10333150
75E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.09630386
76POU3F2_20337985_ChIP-ChIP_501MEL_Human1.09378351
77HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.09293326
78CIITA_25753668_ChIP-Seq_RAJI_Human1.08549142
79PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.07987228
80TFEB_21752829_ChIP-Seq_HELA_Human1.07745011
81NANOG_16153702_ChIP-ChIP_HESCs_Human1.06487591
82SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.05927422
83POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.04642662
84CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.04001398
85MYB_21317192_ChIP-Seq_ERMYB_Mouse1.02082914
86YY1_21170310_ChIP-Seq_MESCs_Mouse0.99324580
87SOX17_20123909_ChIP-Seq_XEN_Mouse0.98886940
88POU5F1_16153702_ChIP-ChIP_HESCs_Human0.97726837
89SOX2_18555785_ChIP-Seq_MESCs_Mouse0.97402538
90NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.96851671
91KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.95643187
92SRF_21415370_ChIP-Seq_HL-1_Mouse0.95396234
93ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.94936362
94TP63_19390658_ChIP-ChIP_HaCaT_Human0.94088528
95SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.93950319
96IRF8_21731497_ChIP-ChIP_J774_Mouse0.91721806
97RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.89800906
98ELK1_22589737_ChIP-Seq_MCF10A_Human0.89178807
99NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.88461747
100STAT4_19710469_ChIP-ChIP_TH1__Mouse0.87909778
101BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.87750932
102MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.86985410
103STAT3_1855785_ChIP-Seq_MESCs_Mouse0.85678010
104FLI1_27457419_Chip-Seq_LIVER_Mouse0.85187458
105MYB_26560356_Chip-Seq_TH2_Human0.84131689
106KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.82765461
107KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.82765461
108KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.82765461
109FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.82620211
110VDR_21846776_ChIP-Seq_THP-1_Human0.80723643
111MYB_26560356_Chip-Seq_TH1_Human0.80637732
112NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.79239795
113CHD1_26751641_Chip-Seq_LNCaP_Human0.78945654
114DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.77805677
115FUS_26573619_Chip-Seq_HEK293_Human0.77285464
116EWS_26573619_Chip-Seq_HEK293_Human0.76956369
117NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.76630805
118BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.76559570
119SOX2_16153702_ChIP-ChIP_HESCs_Human0.76185920
120TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.75502550
121CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.74383253
122CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.73571301
123TCF3_18692474_ChIP-Seq_MEFs_Mouse0.73236574
124SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.72733131
125CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.71023530
126SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.70848147
127IRF1_19129219_ChIP-ChIP_H3396_Human0.70099452

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication5.25181861
2MP0009697_abnormal_copulation4.74150711
3MP0003693_abnormal_embryo_hatching4.27762305
4MP0010094_abnormal_chromosome_stability4.24858233
5MP0004957_abnormal_blastocyst_morpholog3.79489764
6MP0003077_abnormal_cell_cycle3.24980785
7MP0003111_abnormal_nucleus_morphology3.21821342
8MP0008058_abnormal_DNA_repair3.11264455
9MP0010234_abnormal_vibrissa_follicle2.79861212
10MP0003123_paternal_imprinting2.36762639
11MP0008007_abnormal_cellular_replicative2.26841586
12MP0008932_abnormal_embryonic_tissue2.23765726
13MP0010352_gastrointestinal_tract_polyps2.17455431
14MP0002396_abnormal_hematopoietic_system2.17253197
15MP0010307_abnormal_tumor_latency2.11022635
16MP0006035_abnormal_mitochondrial_morpho2.10609657
17MP0000350_abnormal_cell_proliferation2.03473038
18MP0006054_spinal_hemorrhage1.97197612
19MP0009379_abnormal_foot_pigmentation1.88734402
20MP0005397_hematopoietic_system_phenotyp1.88288437
21MP0001545_abnormal_hematopoietic_system1.88288437
22MP0002254_reproductive_system_inflammat1.88266579
23MP0001730_embryonic_growth_arrest1.80675935
24MP0003221_abnormal_cardiomyocyte_apopto1.77254303
25MP0004185_abnormal_adipocyte_glucose1.77000111
26MP0001835_abnormal_antigen_presentation1.74622898
27MP0004147_increased_porphyrin_level1.72481566
28MP0005671_abnormal_response_to1.67879972
29MP0000490_abnormal_crypts_of1.65509611
30MP0009333_abnormal_splenocyte_physiolog1.62627893
31MP0003941_abnormal_skin_development1.62530541
32MP0002398_abnormal_bone_marrow1.61040776
33MP0004808_abnormal_hematopoietic_stem1.56839564
34MP0000685_abnormal_immune_system1.54941030
35MP0006036_abnormal_mitochondrial_physio1.51358669
36MP0008877_abnormal_DNA_methylation1.50934963
37MP0003315_abnormal_perineum_morphology1.50261137
38MP0001697_abnormal_embryo_size1.46311187
39MP0003763_abnormal_thymus_physiology1.44814125
40MP0000537_abnormal_urethra_morphology1.43880180
41MP0000703_abnormal_thymus_morphology1.42168618
42MP0001800_abnormal_humoral_immune1.40193278
43MP0000358_abnormal_cell_content/1.34864487
44MP0002722_abnormal_immune_system1.34782929
45MP0006292_abnormal_olfactory_placode1.34549022
46MP0002019_abnormal_tumor_incidence1.34450173
47MP0005464_abnormal_platelet_physiology1.33855504
48MP0005084_abnormal_gallbladder_morpholo1.33536957
49MP0003786_premature_aging1.27948257
50MP0000313_abnormal_cell_death1.27272652
51MP0000689_abnormal_spleen_morphology1.26780001
52MP0003890_abnormal_embryonic-extraembry1.25313057
53MP0002452_abnormal_antigen_presenting1.25124429
54MP0001348_abnormal_lacrimal_gland1.24702174
55MP0002080_prenatal_lethality1.24386451
56MP0002086_abnormal_extraembryonic_tissu1.23160190
57MP0000716_abnormal_immune_system1.21375476
58MP0002429_abnormal_blood_cell1.21028956
59MP0001672_abnormal_embryogenesis/_devel1.19091435
60MP0005380_embryogenesis_phenotype1.19091435
61MP0001819_abnormal_immune_cell1.17622609
62MP0002420_abnormal_adaptive_immunity1.17110393
63MP0001853_heart_inflammation1.16737043
64MP0002210_abnormal_sex_determination1.16050614
65MP0005187_abnormal_penis_morphology1.15634817
66MP0002090_abnormal_vision1.15167240
67MP0002723_abnormal_immune_serum1.14695569
68MP0003567_abnormal_fetal_cardiomyocyte1.13937627
69MP0002085_abnormal_embryonic_tissue1.13541802
70MP0002277_abnormal_respiratory_mucosa1.12590697
71MP0001293_anophthalmia1.11706259
72MP0002084_abnormal_developmental_patter1.10622178
73MP0009672_abnormal_birth_weight1.08489859
74MP0001145_abnormal_male_reproductive1.06791867
75MP0002160_abnormal_reproductive_system1.06158974
76MP0001661_extended_life_span1.06114755
77MP0003937_abnormal_limbs/digits/tail_de1.05443941
78MP0001879_abnormal_lymphatic_vessel1.05240379
79MP0002405_respiratory_system_inflammati1.04823559
80MP0009785_altered_susceptibility_to1.04724501
81MP0003984_embryonic_growth_retardation1.04430876
82MP0002088_abnormal_embryonic_growth/wei1.04156654
83MP0003121_genomic_imprinting1.03719846
84MP0000858_altered_metastatic_potential1.03038295
85MP0005000_abnormal_immune_tolerance1.02185442
86MP0001919_abnormal_reproductive_system1.00679229
87MP0003136_yellow_coat_color0.99511813
88MP0005501_abnormal_skin_physiology0.99311328
89MP0002006_tumorigenesis0.98919900
90MP0004197_abnormal_fetal_growth/weight/0.98375002
91MP0003252_abnormal_bile_duct0.96960343
92MP0002233_abnormal_nose_morphology0.95882826
93MP0002796_impaired_skin_barrier0.94669790
94MP0002166_altered_tumor_susceptibility0.94399822
95MP0001873_stomach_inflammation0.93411321
96MP0003656_abnormal_erythrocyte_physiolo0.93084997
97MP0001929_abnormal_gametogenesis0.93018773
98MP0003718_maternal_effect0.92322021
99MP0005025_abnormal_response_to0.91169423
100MP0001727_abnormal_embryo_implantation0.90882108
101MP0003119_abnormal_digestive_system0.88106266
102MP0002638_abnormal_pupillary_reflex0.87846639
103MP0001915_intracranial_hemorrhage0.87837999
104MP0000383_abnormal_hair_follicle0.86342445
105MP0009278_abnormal_bone_marrow0.85250186
106MP0001286_abnormal_eye_development0.84944703
107MP0000653_abnormal_sex_gland0.84722841
108MP0002009_preneoplasia0.83629290
109MP0005076_abnormal_cell_differentiation0.82264795
110MP0009703_decreased_birth_body0.81512978
111MP0005395_other_phenotype0.81247018
112MP0002938_white_spotting0.80418500
113MP0005410_abnormal_fertilization0.80387585
114MP0001881_abnormal_mammary_gland0.79665139
115MP0001790_abnormal_immune_system0.79212357
116MP0005387_immune_system_phenotype0.79212357
117MP0003448_altered_tumor_morphology0.78297742
118MP0002111_abnormal_tail_morphology0.76896932
119MP0005389_reproductive_system_phenotype0.76556959
120MP0005384_cellular_phenotype0.75539762
121MP0004264_abnormal_extraembryonic_tissu0.75374610
122MP0000627_abnormal_mammary_gland0.75351175
123MP0002697_abnormal_eye_size0.74964421
124MP0002877_abnormal_melanocyte_morpholog0.74539681
125MP0002148_abnormal_hypersensitivity_rea0.74391850
126MP0010155_abnormal_intestine_physiology0.74216988
127MP0005174_abnormal_tail_pigmentation0.74075589
128MP0002138_abnormal_hepatobiliary_system0.74040575
129MP0003806_abnormal_nucleotide_metabolis0.73231404
130MP0001666_abnormal_nutrient_absorption0.73107380
131MP0002092_abnormal_eye_morphology0.72983744
132MP0001188_hyperpigmentation0.72800215
133MP0002419_abnormal_innate_immunity0.72742251
134MP0005365_abnormal_bile_salt0.72526676
135MP0010678_abnormal_skin_adnexa0.71878824
136MP0005367_renal/urinary_system_phenotyp0.71825100
137MP0000516_abnormal_urinary_system0.71825100
138MP0002139_abnormal_hepatobiliary_system0.71625946
139MP0003936_abnormal_reproductive_system0.69998927
140MP0003186_abnormal_redox_activity0.68993588
141MP0003303_peritoneal_inflammation0.68871943
142MP0004215_abnormal_myocardial_fiber0.68065512
143MP0000647_abnormal_sebaceous_gland0.66248064
144MP0003699_abnormal_female_reproductive0.64019955
145MP0002751_abnormal_autonomic_nervous0.61461966
146MP0003385_abnormal_body_wall0.59783600
147MP0005332_abnormal_amino_acid0.59351591
148MP0003943_abnormal_hepatobiliary_system0.58705214
149MP0005220_abnormal_exocrine_pancreas0.57245532
150MP0009053_abnormal_anal_canal0.56917180
151MP0001119_abnormal_female_reproductive0.55651458

Predicted human phenotypes

RankGene SetZ-score
1Progressive external ophthalmoplegia (HP:0000590)5.54044958
2Sensory axonal neuropathy (HP:0003390)5.17821578
3Reticulocytopenia (HP:0001896)5.07299935
4Abnormality of cells of the erythroid lineage (HP:0012130)4.66238382
5Abnormal number of erythroid precursors (HP:0012131)4.38851133
6Progressive inability to walk (HP:0002505)4.14564306
7Birth length less than 3rd percentile (HP:0003561)4.02894105
8Premature ovarian failure (HP:0008209)4.02150795
9Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.68394621
10Pallor (HP:0000980)3.67247335
11Ragged-red muscle fibers (HP:0003200)3.54677878
12Fatigue (HP:0012378)3.42134241
13Macrocytic anemia (HP:0001972)3.41177884
14Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.36336501
15Nephroblastoma (Wilms tumor) (HP:0002667)3.15202725
16Chromsome breakage (HP:0040012)3.12688374
17Colon cancer (HP:0003003)3.07698842
18Embryonal renal neoplasm (HP:0011794)3.03957781
19Abnormality of chromosome stability (HP:0003220)3.00244774
20Abnormality of methionine metabolism (HP:0010901)2.98160668
21Supernumerary spleens (HP:0009799)2.97825600
22Impaired proprioception (HP:0010831)2.97258987
23Multiple enchondromatosis (HP:0005701)2.93482101
24Abnormality of the preputium (HP:0100587)2.81555919
25Increased hepatocellular lipid droplets (HP:0006565)2.79877164
26Spastic diplegia (HP:0001264)2.77033810
27Breast hypoplasia (HP:0003187)2.76773260
28Abnormality of the heme biosynthetic pathway (HP:0010472)2.74879030
29Dysphonia (HP:0001618)2.73872315
30Oral leukoplakia (HP:0002745)2.71675291
31Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.69671363
32Chromosomal breakage induced by crosslinking agents (HP:0003221)2.69583526
33Rough bone trabeculation (HP:0100670)2.68710625
3411 pairs of ribs (HP:0000878)2.67420476
35Absent thumb (HP:0009777)2.63891656
36Pancreatic islet-cell hyperplasia (HP:0004510)2.62554940
37Chronic otitis media (HP:0000389)2.60141177
38Increased serum pyruvate (HP:0003542)2.59172128
39Abnormal lung lobation (HP:0002101)2.55284207
40Myelodysplasia (HP:0002863)2.53898844
41Progressive hearing impairment (HP:0001730)2.53127710
42Aplastic anemia (HP:0001915)2.52882037
43Meckel diverticulum (HP:0002245)2.52137858
44Absent radius (HP:0003974)2.51841332
45Abnormality of aspartate family amino acid metabolism (HP:0010899)2.50546173
46Neoplasm of the pancreas (HP:0002894)2.47618756
47Premature graying of hair (HP:0002216)2.46052150
48Aplasia involving forearm bones (HP:0009822)2.44227348
49Absent forearm bone (HP:0003953)2.44227348
50Lymphoma (HP:0002665)2.42355566
51Asplenia (HP:0001746)2.41566638
52Agnosia (HP:0010524)2.40957799
53Bone marrow hypocellularity (HP:0005528)2.40595326
54Facial hemangioma (HP:0000329)2.40543218
55Aplasia/Hypoplasia of the uvula (HP:0010293)2.38795389
56Lipid accumulation in hepatocytes (HP:0006561)2.37078160
57Volvulus (HP:0002580)2.33257062
58Hypergonadotropic hypogonadism (HP:0000815)2.32922040
59Renal Fanconi syndrome (HP:0001994)2.31755598
60Patellar aplasia (HP:0006443)2.31090779
61Abnormality of the ileum (HP:0001549)2.29630244
62Neoplasm of the colon (HP:0100273)2.27600296
63Glossoptosis (HP:0000162)2.27537335
64Biliary tract neoplasm (HP:0100574)2.23766665
65Aplasia/Hypoplasia of the spleen (HP:0010451)2.23678793
66Amaurosis fugax (HP:0100576)2.23170526
67Chronic obstructive pulmonary disease (HP:0006510)2.22452822
68Obstructive lung disease (HP:0006536)2.22452822
69Median cleft lip (HP:0000161)2.21844146
70Abnormality of glycolysis (HP:0004366)2.20576642
71Degeneration of anterior horn cells (HP:0002398)2.19924714
72Abnormality of the anterior horn cell (HP:0006802)2.19924714
73Basal cell carcinoma (HP:0002671)2.18498865
74Abnormal trabecular bone morphology (HP:0100671)2.16189414
75Gonadotropin excess (HP:0000837)2.15666514
76Cleft eyelid (HP:0000625)2.15472186
77Abnormality of the duodenum (HP:0002246)2.14600709
78Squamous cell carcinoma (HP:0002860)2.13753342
79Acute myeloid leukemia (HP:0004808)2.13624849
80Increased serum lactate (HP:0002151)2.11840128
81Impulsivity (HP:0100710)2.11522189
82Abnormality of reticulocytes (HP:0004312)2.11474889
83Aplasia/Hypoplasia of the sacrum (HP:0008517)2.11189572
84Abnormality of serum amino acid levels (HP:0003112)2.11008740
85Atresia of the external auditory canal (HP:0000413)2.10836842
86Microretrognathia (HP:0000308)2.10275636
87Selective tooth agenesis (HP:0001592)2.08177099
88Aplasia/Hypoplasia of the patella (HP:0006498)2.07719928
89Pancreatic fibrosis (HP:0100732)2.07568129
90Abnormality of DNA repair (HP:0003254)2.07000887
91Abnormal delayed hypersensitivity skin test (HP:0002963)2.06749400
92Pancytopenia (HP:0001876)2.06028301
93Hypoglycemic seizures (HP:0002173)2.03937488
94Poor eye contact (HP:0000817)2.03303366
95Prominent metopic ridge (HP:0005487)2.00741224
96Abnormal spermatogenesis (HP:0008669)2.00583639
97Abnormality of the labia minora (HP:0012880)2.00134422
98Increased mean platelet volume (HP:0011877)1.99870685
99Chronic mucocutaneous candidiasis (HP:0002728)1.99442378
100Recurrent cutaneous fungal infections (HP:0011370)1.99442378
101Acute encephalopathy (HP:0006846)1.98566530
102Panhypogammaglobulinemia (HP:0003139)1.98192607
103Pancreatic cysts (HP:0001737)1.98069587
104Disinhibition (HP:0000734)1.97900510
105Tracheoesophageal fistula (HP:0002575)1.96422360
106Papillary thyroid carcinoma (HP:0002895)1.96409707
107Acute necrotizing encephalopathy (HP:0006965)1.96179312
108Ovarian neoplasm (HP:0100615)1.95787604
109Recurrent viral infections (HP:0004429)1.95601732
110IgG deficiency (HP:0004315)1.95555847
111Reduced antithrombin III activity (HP:0001976)1.95241348
112Duplicated collecting system (HP:0000081)1.95120462
113Proximal placement of thumb (HP:0009623)1.94314352
114Cellular immunodeficiency (HP:0005374)1.93801837
115Horseshoe kidney (HP:0000085)1.93750003
116Small intestinal stenosis (HP:0012848)1.93090029
117Duodenal stenosis (HP:0100867)1.93090029
118Increased nuchal translucency (HP:0010880)1.92621497
119Facial cleft (HP:0002006)1.92546955
120Recurrent fungal infections (HP:0002841)1.92138842
121External ophthalmoplegia (HP:0000544)1.90200383
122Hypertensive crisis (HP:0100735)1.90197713
123Cerebral hypomyelination (HP:0006808)1.89766367
124Sloping forehead (HP:0000340)1.88482680
125Triphalangeal thumb (HP:0001199)1.88176647
126Clumsiness (HP:0002312)1.87989434
127Thrombocytosis (HP:0001894)1.87390507
128Mediastinal lymphadenopathy (HP:0100721)1.87239830
129Cerebral edema (HP:0002181)1.86616297
130Capillary hemangiomas (HP:0005306)1.86524737
131Symptomatic seizures (HP:0011145)1.86142893
132Trismus (HP:0000211)1.85576027
133Paralysis (HP:0003470)1.84608270
134Progressive muscle weakness (HP:0003323)1.84367712
135Poikiloderma (HP:0001029)1.84347085
136Abnormality of lateral ventricle (HP:0030047)1.84346302
137Inability to walk (HP:0002540)1.83459855
138Abnormality of endocrine pancreas physiology (HP:0012093)1.83000214
139Abnormality of the pancreatic islet cells (HP:0006476)1.83000214
140Abdominal situs inversus (HP:0003363)1.82821036
141Abnormality of abdominal situs (HP:0011620)1.82821036
142Deviation of the thumb (HP:0009603)1.82635412
143Posterior subcapsular cataract (HP:0007787)1.82331278
144Embryonal neoplasm (HP:0002898)1.82131159
145Hypoglycemic coma (HP:0001325)1.81745088
146Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.81658006
147Abnormality of alanine metabolism (HP:0010916)1.81658006
148Hyperalaninemia (HP:0003348)1.81658006
149Increased intramyocellular lipid droplets (HP:0012240)1.81332160
150Abnormality of the carotid arteries (HP:0005344)1.80335659
151IgM deficiency (HP:0002850)1.79264378
152Exercise intolerance (HP:0003546)1.78240743
153Neoplasm of the adrenal gland (HP:0100631)1.76626432
154Amniotic constriction ring (HP:0009775)1.76624978
155Abnormality of placental membranes (HP:0011409)1.76624978
156Encephalitis (HP:0002383)1.76406505
157Thyroid carcinoma (HP:0002890)1.76188602
158Leukopenia (HP:0001882)1.76139987
159Rhinitis (HP:0012384)1.75810499
160Entropion (HP:0000621)1.75574706
161Hyperglycinuria (HP:0003108)1.75544268
162Ependymoma (HP:0002888)1.75027127
163Acanthocytosis (HP:0001927)1.75000834
164Dyschromatopsia (HP:0007641)1.74932269
165Cortical dysplasia (HP:0002539)1.74556384
166Aplasia/Hypoplasia of the thymus (HP:0010515)1.73191250
167Rhabdomyosarcoma (HP:0002859)1.72707201
168Molar tooth sign on MRI (HP:0002419)1.72266761
169Abnormality of midbrain morphology (HP:0002418)1.72266761
170Medulloblastoma (HP:0002885)1.72035705
171Hypoplasia of the uterus (HP:0000013)1.71599831
172Neoplasm of the small intestine (HP:0100833)1.71158815
173Uterine neoplasm (HP:0010784)1.70051971
174Irregular epiphyses (HP:0010582)1.69786440
175Atrophy/Degeneration involving motor neurons (HP:0007373)1.69695640
176Clubbing of toes (HP:0100760)1.68775656

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WEE14.57519656
2CDC73.85450705
3ZAK3.20346166
4BUB13.12366941
5SRPK13.02777413
6STK162.97857610
7NEK12.70183818
8NME22.70005312
9BRSK22.55450480
10DYRK32.50193860
11EIF2AK12.38929325
12VRK12.31176226
13SCYL22.31016587
14NEK22.30723592
15ACVR1B2.30632808
16TSSK62.01993975
17TLK12.00818433
18EIF2AK31.87599952
19VRK21.61069052
20PNCK1.60352015
21PLK11.58453699
22RPS6KB21.50497401
23TRIM281.50078532
24TNIK1.48487542
25RIPK41.47368091
26MKNK11.44786479
27MST41.43754139
28NLK1.40736507
29JAK31.40076394
30STK101.38751486
31CDK41.38106146
32MKNK21.37688694
33PIM21.33486815
34AURKB1.33250699
35PLK41.32709998
36ATR1.30311845
37TAF11.27090677
38BLK1.22800026
39PLK31.21286112
40CDK71.20266535
41MAP4K11.18219029
42CDK61.14949714
43MAP2K31.14921758
44TEC1.14286060
45PBK1.13936719
46RPS6KA41.13792082
47CHEK21.13381592
48TTK1.13234570
49MARK31.11670924
50MAP3K111.09124426
51MAP3K81.08597304
52BRD41.07993177
53MAPKAPK31.05521670
54TGFBR11.03462576
55ERBB31.03414041
56TAOK21.02356698
57PASK1.02130405
58FLT31.01131192
59IRAK40.99075385
60PIM10.92716154
61KIT0.92513738
62YES10.92345783
63BRSK10.91200735
64BTK0.89996731
65GRK60.89709167
66* CHEK10.88504301
67AKT20.83442708
68MAP3K140.82938562
69MAPKAPK50.82498939
70ATM0.81148492
71CDK120.79509086
72WNK30.78701371
73FGR0.78171124
74MAP3K30.77397467
75SIK20.77013694
76RPS6KA50.76231050
77MELK0.71830067
78CSNK2A20.71353625
79EIF2AK20.68401236
80MAP3K40.68072602
81RAF10.66148029
82BRAF0.64426490
83PAK40.64326622
84MAP3K120.62773420
85AURKA0.61096389
86PRKCI0.60255640
87CCNB10.60219130
88CDK20.59438707
89WNK40.57308896
90STK38L0.56892425
91STK240.56627350
92MST1R0.56493743
93LIMK10.56392763
94CDK80.56147368
95STK30.55366186
96EEF2K0.55189827
97ERBB40.54731002
98ALK0.53683066
99TYK20.53256099
100STK390.52865674
101CSNK2A10.52731401
102MAP3K50.52479276
103STK40.51460962
104IKBKB0.51262927
105MAP3K100.51190941
106TRPM70.49431984
107LCK0.49109860
108LYN0.46159056
109TAOK10.45316197
110LRRK20.45129835
111ITK0.44989604
112SYK0.44456439
113ABL20.43046769
114MATK0.41798233
115MAP2K70.41284899
116OXSR10.41238555
117FGFR10.40879500
118MET0.39448550
119CSF1R0.38541319
120CDK190.38538737
121CSNK1E0.38152348
122BMPR1B0.37370448
123CDK10.35713229
124MAP3K130.35574754
125DYRK20.34741930
126NUAK10.34676890
127NTRK30.34392656
128PLK20.33871829
129EPHA20.33379048
130PDK20.30699532
131RPS6KB10.30672737
132CDK30.29311311
133PAK10.28751539
134PRKACB0.22292263
135NEK90.21794060
136LATS10.21431646
137BCR0.21076890
138MAP3K20.21002054
139MAP3K60.20805404
140CDK90.19344540

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.59631169
2Ribosome_Homo sapiens_hsa030103.90644110
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.85476617
4Mismatch repair_Homo sapiens_hsa034303.75158917
5Spliceosome_Homo sapiens_hsa030403.27309994
6Homologous recombination_Homo sapiens_hsa034403.19750371
7Nucleotide excision repair_Homo sapiens_hsa034202.77995391
8RNA polymerase_Homo sapiens_hsa030202.71360031
9Proteasome_Homo sapiens_hsa030502.64123796
10RNA transport_Homo sapiens_hsa030132.63007057
11Fanconi anemia pathway_Homo sapiens_hsa034602.44537838
12One carbon pool by folate_Homo sapiens_hsa006702.39266795
13Cell cycle_Homo sapiens_hsa041102.37576322
14Base excision repair_Homo sapiens_hsa034102.30095441
15Non-homologous end-joining_Homo sapiens_hsa034502.10869418
16Pyrimidine metabolism_Homo sapiens_hsa002402.09056850
17Basal transcription factors_Homo sapiens_hsa030221.95308139
18Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.84612858
19RNA degradation_Homo sapiens_hsa030181.69464641
20Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.62137948
21p53 signaling pathway_Homo sapiens_hsa041151.61724186
22Antigen processing and presentation_Homo sapiens_hsa046121.58230255
23Systemic lupus erythematosus_Homo sapiens_hsa053221.55848025
24Sulfur metabolism_Homo sapiens_hsa009201.50480041
25Propanoate metabolism_Homo sapiens_hsa006401.44716058
26Pyruvate metabolism_Homo sapiens_hsa006201.44205302
27Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.43530084
28Selenocompound metabolism_Homo sapiens_hsa004501.40123876
29mRNA surveillance pathway_Homo sapiens_hsa030151.38579385
30Glutathione metabolism_Homo sapiens_hsa004801.36888265
31Primary immunodeficiency_Homo sapiens_hsa053401.35585385
32Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.33000289
33Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.30090816
34Herpes simplex infection_Homo sapiens_hsa051681.25816978
35NOD-like receptor signaling pathway_Homo sapiens_hsa046211.19958832
36Epstein-Barr virus infection_Homo sapiens_hsa051691.18029704
37NF-kappa B signaling pathway_Homo sapiens_hsa040641.17647522
38Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.12000423
39Fatty acid elongation_Homo sapiens_hsa000621.11747883
40Purine metabolism_Homo sapiens_hsa002301.11523967
41Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.06824504
422-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.05378159
43Steroid biosynthesis_Homo sapiens_hsa001001.04478326
44Viral carcinogenesis_Homo sapiens_hsa052030.99760117
45Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.99474675
46Protein export_Homo sapiens_hsa030600.97588926
47beta-Alanine metabolism_Homo sapiens_hsa004100.97418031
48RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.96618678
49Biosynthesis of amino acids_Homo sapiens_hsa012300.96523734
50HTLV-I infection_Homo sapiens_hsa051660.94972154
51Pentose and glucuronate interconversions_Homo sapiens_hsa000400.93302540
52Olfactory transduction_Homo sapiens_hsa047400.92010035
53Allograft rejection_Homo sapiens_hsa053300.89904035
54Carbon metabolism_Homo sapiens_hsa012000.86109457
55Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.84998318
56Measles_Homo sapiens_hsa051620.83777997
57Arginine and proline metabolism_Homo sapiens_hsa003300.81492867
58Shigellosis_Homo sapiens_hsa051310.81317098
59Adherens junction_Homo sapiens_hsa045200.80642699
60Transcriptional misregulation in cancer_Homo sapiens_hsa052020.80561867
61Intestinal immune network for IgA production_Homo sapiens_hsa046720.79689025
62Tight junction_Homo sapiens_hsa045300.77954734
63Hepatitis B_Homo sapiens_hsa051610.77814950
64Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.77701457
65Small cell lung cancer_Homo sapiens_hsa052220.77348674
66Oocyte meiosis_Homo sapiens_hsa041140.76682324
67Leishmaniasis_Homo sapiens_hsa051400.76424235
68Regulation of autophagy_Homo sapiens_hsa041400.76099993
69Thyroid cancer_Homo sapiens_hsa052160.75091286
70Legionellosis_Homo sapiens_hsa051340.74515047
71Parkinsons disease_Homo sapiens_hsa050120.73715387
72Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.73119122
73Vitamin B6 metabolism_Homo sapiens_hsa007500.73080074
74B cell receptor signaling pathway_Homo sapiens_hsa046620.72671555
75Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.72186450
76Hematopoietic cell lineage_Homo sapiens_hsa046400.71119331
77Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.70692239
78Asthma_Homo sapiens_hsa053100.68774638
79Apoptosis_Homo sapiens_hsa042100.67655220
80Folate biosynthesis_Homo sapiens_hsa007900.65574022
81Fat digestion and absorption_Homo sapiens_hsa049750.64773552
82Type I diabetes mellitus_Homo sapiens_hsa049400.64277120
83Alcoholism_Homo sapiens_hsa050340.61637252
84Chronic myeloid leukemia_Homo sapiens_hsa052200.61001683
85Wnt signaling pathway_Homo sapiens_hsa043100.58947604
86MicroRNAs in cancer_Homo sapiens_hsa052060.57497477
87Influenza A_Homo sapiens_hsa051640.57386245
88Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.54977763
89Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.54617907
90Butanoate metabolism_Homo sapiens_hsa006500.53995424
91Colorectal cancer_Homo sapiens_hsa052100.53890359
92Cysteine and methionine metabolism_Homo sapiens_hsa002700.53352299
93Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.53260369
94Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.53096206
95Metabolic pathways_Homo sapiens_hsa011000.52367029
96Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.50903737
97Peroxisome_Homo sapiens_hsa041460.50719395
98TGF-beta signaling pathway_Homo sapiens_hsa043500.49545433
99Caffeine metabolism_Homo sapiens_hsa002320.47714510
100TNF signaling pathway_Homo sapiens_hsa046680.46585373
101Primary bile acid biosynthesis_Homo sapiens_hsa001200.45840170
102Oxidative phosphorylation_Homo sapiens_hsa001900.45630897
103Sulfur relay system_Homo sapiens_hsa041220.45252939
104alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.44574659
105Acute myeloid leukemia_Homo sapiens_hsa052210.44078968
106Fatty acid degradation_Homo sapiens_hsa000710.43949862
107Linoleic acid metabolism_Homo sapiens_hsa005910.43741731
108SNARE interactions in vesicular transport_Homo sapiens_hsa041300.43617217
109Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.43611970
110Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.43341515
111Fatty acid metabolism_Homo sapiens_hsa012120.43178387
112Toll-like receptor signaling pathway_Homo sapiens_hsa046200.42636516
113Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.42333402
114Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.41944320
115T cell receptor signaling pathway_Homo sapiens_hsa046600.41218755
116Ether lipid metabolism_Homo sapiens_hsa005650.41175421
117Toxoplasmosis_Homo sapiens_hsa051450.40303397
118Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.39628882
119Graft-versus-host disease_Homo sapiens_hsa053320.37905791
120Prostate cancer_Homo sapiens_hsa052150.37789709
121Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.37570679
122Osteoclast differentiation_Homo sapiens_hsa043800.36763129
123Bladder cancer_Homo sapiens_hsa052190.36391595
124Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.36049192
125Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.35682180
126Jak-STAT signaling pathway_Homo sapiens_hsa046300.35199861
127Nitrogen metabolism_Homo sapiens_hsa009100.34585887
128Huntingtons disease_Homo sapiens_hsa050160.32774288
129Pancreatic cancer_Homo sapiens_hsa052120.32726914
130Retinol metabolism_Homo sapiens_hsa008300.32566017
131N-Glycan biosynthesis_Homo sapiens_hsa005100.31653034
132Renin-angiotensin system_Homo sapiens_hsa046140.31564120
133Pathways in cancer_Homo sapiens_hsa052000.31210912
134Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.29974701
135Arachidonic acid metabolism_Homo sapiens_hsa005900.29877729
136Melanoma_Homo sapiens_hsa052180.29369706
137Tuberculosis_Homo sapiens_hsa051520.27809505
138Pentose phosphate pathway_Homo sapiens_hsa000300.27797740
139African trypanosomiasis_Homo sapiens_hsa051430.26814693
140Chemokine signaling pathway_Homo sapiens_hsa040620.25807857
141Pertussis_Homo sapiens_hsa051330.25434548
142Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.24546543
143Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.24222389
144Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.23727609
145Autoimmune thyroid disease_Homo sapiens_hsa053200.23082099
146Steroid hormone biosynthesis_Homo sapiens_hsa001400.22608891
147Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.21207496
148Arginine biosynthesis_Homo sapiens_hsa002200.20131967
149Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.19584291
150Leukocyte transendothelial migration_Homo sapiens_hsa046700.18610856
151Malaria_Homo sapiens_hsa051440.17246368
152Other glycan degradation_Homo sapiens_hsa005110.16152636
153Drug metabolism - other enzymes_Homo sapiens_hsa009830.15488290
154Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.13252107
155AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.13185826

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »