CABP7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)6.69565198
2regulation of short-term neuronal synaptic plasticity (GO:0048172)6.39505922
3locomotory exploration behavior (GO:0035641)6.38202026
4behavioral response to nicotine (GO:0035095)6.30944076
5positive regulation of calcium ion-dependent exocytosis (GO:0045956)6.03400371
6positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.73531516
7neuronal action potential propagation (GO:0019227)5.51075094
8regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.26938273
9synaptic vesicle exocytosis (GO:0016079)5.25144591
10synaptic vesicle docking involved in exocytosis (GO:0016081)5.19014161
11regulation of neuronal synaptic plasticity (GO:0048168)5.17796195
12glutamate secretion (GO:0014047)5.13267462
13regulation of glutamate receptor signaling pathway (GO:1900449)5.08590811
14regulation of synaptic vesicle exocytosis (GO:2000300)5.06874254
15exploration behavior (GO:0035640)4.95080811
16ionotropic glutamate receptor signaling pathway (GO:0035235)4.90377832
17vocalization behavior (GO:0071625)4.89854536
18regulation of synaptic vesicle transport (GO:1902803)4.70423267
19neurotransmitter secretion (GO:0007269)4.68859163
20regulation of long-term neuronal synaptic plasticity (GO:0048169)4.57948728
21sodium ion export (GO:0071436)4.56753174
22synaptic transmission, glutamatergic (GO:0035249)4.47699756
23long-term memory (GO:0007616)4.47458629
24cell communication by electrical coupling involved in cardiac conduction (GO:0086064)4.45481586
25cellular potassium ion homeostasis (GO:0030007)4.43122576
26neuromuscular process controlling posture (GO:0050884)4.40071945
27negative regulation of protein oligomerization (GO:0032460)4.24946366
28protein localization to synapse (GO:0035418)4.23134888
29membrane depolarization during cardiac muscle cell action potential (GO:0086012)4.21056712
30endocrine pancreas development (GO:0031018)4.15287437
31cell communication by electrical coupling (GO:0010644)4.10545875
32glutamate receptor signaling pathway (GO:0007215)4.10119422
33regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.10030180
34positive regulation of membrane potential (GO:0045838)4.09242949
35chemosensory behavior (GO:0007635)4.09163702
36L-amino acid import (GO:0043092)4.08822264
37regulation of type B pancreatic cell apoptotic process (GO:2000674)4.01792430
38positive regulation of growth hormone secretion (GO:0060124)3.98373874
39regulation of synapse structural plasticity (GO:0051823)3.92564395
40positive regulation of synapse maturation (GO:0090129)3.91977007
41dendritic spine morphogenesis (GO:0060997)3.91271470
42regulation of synaptic plasticity (GO:0048167)3.90873057
43neuron-neuron synaptic transmission (GO:0007270)3.86791751
44innervation (GO:0060384)3.85212170
45regulation of ARF protein signal transduction (GO:0032012)3.80466813
46nitric oxide mediated signal transduction (GO:0007263)3.79739226
47negative regulation of gluconeogenesis (GO:0045721)3.78725014
48neurotransmitter transport (GO:0006836)3.77870507
49cerebellar Purkinje cell layer development (GO:0021680)3.73754706
50regulation of excitatory postsynaptic membrane potential (GO:0060079)3.72803910
51positive regulation of respiratory burst (GO:0060267)3.66809625
52activation of protein kinase A activity (GO:0034199)3.66142480
53negative regulation of acute inflammatory response (GO:0002674)3.65947977
54gamma-aminobutyric acid transport (GO:0015812)3.63886672
55potassium ion import (GO:0010107)3.60397411
56proline transport (GO:0015824)3.58792752
57negative regulation of Ras GTPase activity (GO:0034261)3.58318112
58neuromuscular process controlling balance (GO:0050885)3.56458254
59glycine transport (GO:0015816)3.52199102
60cellular sodium ion homeostasis (GO:0006883)3.51672286
61regulation of glucokinase activity (GO:0033131)3.51600662
62regulation of hexokinase activity (GO:1903299)3.51600662
63dendritic spine organization (GO:0097061)3.51448934
64neurotransmitter-gated ion channel clustering (GO:0072578)3.49265803
65regulation of postsynaptic membrane potential (GO:0060078)3.49150399
66mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.48819771
67synaptic vesicle endocytosis (GO:0048488)3.48729798
68protein complex biogenesis (GO:0070271)3.47478246
69regulation of neurotransmitter levels (GO:0001505)3.47161939
70regulation of vesicle fusion (GO:0031338)3.44826754
71transmission of nerve impulse (GO:0019226)3.44026416
72positive regulation of gastrulation (GO:2000543)3.43397944
73positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.42971855
74regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.42328832
75neuron cell-cell adhesion (GO:0007158)3.41787162
76substrate-independent telencephalic tangential interneuron migration (GO:0021843)3.41563730
77substrate-independent telencephalic tangential migration (GO:0021826)3.41563730
78negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.40512174
79cerebellar Purkinje cell differentiation (GO:0021702)3.39792029
80long-term synaptic potentiation (GO:0060291)3.36977275
81dentate gyrus development (GO:0021542)3.36805623
82negative regulation of cytosolic calcium ion concentration (GO:0051481)3.36678893
83pyrimidine nucleobase catabolic process (GO:0006208)3.34160545
84mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.33834990
85mitochondrial respiratory chain complex I assembly (GO:0032981)3.33834990
86NADH dehydrogenase complex assembly (GO:0010257)3.33834990
87regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.32238752
88positive regulation of dendritic spine morphogenesis (GO:0061003)3.31626476
89parturition (GO:0007567)3.29869674
90amino acid import (GO:0043090)3.27799190
91retinal ganglion cell axon guidance (GO:0031290)3.27603503
92regulation of neurotransmitter secretion (GO:0046928)3.26811201
93neuronal ion channel clustering (GO:0045161)3.26480441
94positive regulation of synaptic transmission, GABAergic (GO:0032230)3.25726658
95phenylpropanoid metabolic process (GO:0009698)3.25344974
96membrane depolarization during action potential (GO:0086010)3.23932308
97nucleobase catabolic process (GO:0046113)3.23172112
98layer formation in cerebral cortex (GO:0021819)3.20396230
99glycerophospholipid catabolic process (GO:0046475)3.20173448
100vesicle transport along microtubule (GO:0047496)3.20001536
101cell proliferation in forebrain (GO:0021846)3.19711165
102detection of calcium ion (GO:0005513)3.16982404
103regulation of dendritic spine morphogenesis (GO:0061001)3.14923991
104regulation of calcium ion-dependent exocytosis (GO:0017158)3.14574783
105potassium ion homeostasis (GO:0055075)3.13748107
106axonal fasciculation (GO:0007413)3.13216461
107neuron recognition (GO:0008038)3.11413629
108regulation of synaptic transmission (GO:0050804)3.11291263
109G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.10585976
110positive regulation of dendritic spine development (GO:0060999)3.09262655
111mitochondrial respiratory chain complex assembly (GO:0033108)3.08629596
112positive regulation of vesicle fusion (GO:0031340)3.08474214
113gamma-aminobutyric acid signaling pathway (GO:0007214)3.08358793
114negative regulation of heart rate (GO:0010459)3.08161087
115membrane depolarization (GO:0051899)3.07580301
116water-soluble vitamin biosynthetic process (GO:0042364)3.06930923
117signal complex assembly (GO:0007172)3.05261567
118neuromuscular process (GO:0050905)3.04707600
119dendrite morphogenesis (GO:0048813)3.04255032
120behavioral fear response (GO:0001662)3.03378937
121behavioral defense response (GO:0002209)3.03378937
122positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.01632955
123synaptic transmission (GO:0007268)3.01308513
124regulation of neurotransmitter transport (GO:0051588)2.98424226
125negative regulation of synaptic transmission, GABAergic (GO:0032229)2.97869280
126negative regulation of catecholamine secretion (GO:0033604)2.97411765
127fear response (GO:0042596)2.95706078
128positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.95176417
129regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.94715724
130positive regulation of glycolytic process (GO:0045821)2.94473012
131synaptic transmission, cholinergic (GO:0007271)2.90072453
132positive regulation of synaptic transmission (GO:0050806)2.89393677
133insulin secretion (GO:0030073)2.88723384
134protein polyglutamylation (GO:0018095)2.88604954
135adult walking behavior (GO:0007628)2.87765383
136signal release (GO:0023061)2.87338033
137learning (GO:0007612)2.86363613
138membrane repolarization (GO:0086009)2.85658922
139positive regulation of potassium ion transmembrane transport (GO:1901381)2.85479273
140regulation of respiratory burst (GO:0060263)2.82243973
141membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.81164662
142regulation of growth hormone secretion (GO:0060123)2.80479138
143positive regulation of peptide hormone secretion (GO:0090277)2.79855478
144brain morphogenesis (GO:0048854)2.79167534
145epithelial cilium movement (GO:0003351)2.77675523
146auditory behavior (GO:0031223)2.76669479
147cellular ketone body metabolic process (GO:0046950)2.76629828
148protein neddylation (GO:0045116)2.76435570
149regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022352.75908116
150protein import into peroxisome matrix (GO:0016558)2.75472629
151glandular epithelial cell differentiation (GO:0002067)2.74806450
152establishment of protein localization to mitochondrial membrane (GO:0090151)2.74766903
153membrane repolarization during action potential (GO:0086011)2.72701917
154peristalsis (GO:0030432)2.71807106
155protein localization to cilium (GO:0061512)2.70196495
156positive regulation of peptide secretion (GO:0002793)2.69147538
157ATP synthesis coupled proton transport (GO:0015986)2.68715488
158energy coupled proton transport, down electrochemical gradient (GO:0015985)2.68715488
159nonmotile primary cilium assembly (GO:0035058)2.66527630
160axoneme assembly (GO:0035082)2.64213478
161regulation of feeding behavior (GO:0060259)2.64089480
162type B pancreatic cell development (GO:0003323)2.62797133
163ganglion development (GO:0061548)2.60387971
164nucleoside diphosphate catabolic process (GO:0009134)2.60375490
165positive regulation of insulin secretion (GO:0032024)2.58863362
166DNA deamination (GO:0045006)2.54309308
167negative regulation of glycogen metabolic process (GO:0070874)2.54285180
168electron transport chain (GO:0022900)2.53815779
169calcium ion-dependent exocytosis (GO:0017156)2.53334520
170synapse assembly (GO:0007416)2.53083952
171platelet dense granule organization (GO:0060155)2.52255081
172respiratory electron transport chain (GO:0022904)2.51522713
173neuromuscular synaptic transmission (GO:0007274)2.51463609
174metanephric nephron tubule development (GO:0072234)2.51452748
175metanephric tubule development (GO:0072170)2.51452748
176neuropeptide signaling pathway (GO:0007218)2.51372332
177presynaptic membrane organization (GO:0097090)2.50839501
178chaperone-mediated protein transport (GO:0072321)2.49140830
179mesenchymal cell differentiation involved in renal system development (GO:2001012)2.47726726
180mesenchymal cell differentiation involved in kidney development (GO:0072161)2.47726726
181mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.45406248
182response to nicotine (GO:0035094)2.44771560
183cilium movement (GO:0003341)2.42560245

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.96328252
2* REST_21632747_ChIP-Seq_MESCs_Mouse3.33179414
3FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.32676036
4* SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.18986738
5* JARID2_20064375_ChIP-Seq_MESCs_Mouse3.18837747
6SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.17532696
7RARB_27405468_Chip-Seq_BRAIN_Mouse2.99830003
8JARID2_20075857_ChIP-Seq_MESCs_Mouse2.89648485
9EZH2_18974828_ChIP-Seq_MESCs_Mouse2.88355757
10RNF2_18974828_ChIP-Seq_MESCs_Mouse2.88355757
11* REST_18959480_ChIP-ChIP_MESCs_Mouse2.82186637
12DROSHA_22980978_ChIP-Seq_HELA_Human2.79478060
13GBX2_23144817_ChIP-Seq_PC3_Human2.78980860
14* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.77369656
15IKZF1_21737484_ChIP-ChIP_HCT116_Human2.74840239
16* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.70694288
17* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.60109121
18SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.51419583
19* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.48635299
20* EZH2_27294783_Chip-Seq_ESCs_Mouse2.47421600
21EZH2_27304074_Chip-Seq_ESCs_Mouse2.45736644
22SUZ12_27294783_Chip-Seq_ESCs_Mouse2.45719534
23EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.38093569
24CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.30231806
25* RNF2_27304074_Chip-Seq_ESCs_Mouse2.29385322
26MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.28323771
27TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.26132123
28VDR_22108803_ChIP-Seq_LS180_Human2.23408179
29EED_16625203_ChIP-ChIP_MESCs_Mouse2.23305406
30HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.92078336
31NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.85306058
32* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.78387323
33ERG_21242973_ChIP-ChIP_JURKAT_Human1.78162586
34HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.74393836
35ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.72399638
36ZNF274_21170338_ChIP-Seq_K562_Hela1.70456390
37DNAJC2_21179169_ChIP-ChIP_NT2_Human1.51439781
38GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.48201638
39* RING1B_27294783_Chip-Seq_ESCs_Mouse1.43854976
40NR3C1_23031785_ChIP-Seq_PC12_Mouse1.42414903
41KDM2B_26808549_Chip-Seq_K562_Human1.41869185
42* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.41089841
43* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.39724967
44SMAD4_21799915_ChIP-Seq_A2780_Human1.39634461
45* ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.38569861
46CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.36436327
47CTBP1_25329375_ChIP-Seq_LNCAP_Human1.31051321
48ETV2_25802403_ChIP-Seq_MESCs_Mouse1.30792397
49ZFP57_27257070_Chip-Seq_ESCs_Mouse1.28686910
50SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.28473451
51GABP_17652178_ChIP-ChIP_JURKAT_Human1.26299848
52CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.26101881
53TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.25507537
54AR_21572438_ChIP-Seq_LNCaP_Human1.25344152
55CTBP2_25329375_ChIP-Seq_LNCAP_Human1.24223671
56PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.22367304
57IGF1R_20145208_ChIP-Seq_DFB_Human1.21536008
58IRF1_19129219_ChIP-ChIP_H3396_Human1.20973981
59AR_19668381_ChIP-Seq_PC3_Human1.20733887
60TP53_22573176_ChIP-Seq_HFKS_Human1.19692312
61RBPJ_22232070_ChIP-Seq_NCS_Mouse1.19089022
62WT1_25993318_ChIP-Seq_PODOCYTE_Human1.18556704
63TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.18037653
64POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.18037653
65RING1B_27294783_Chip-Seq_NPCs_Mouse1.17001987
66EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.15920089
67WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.15192963
68RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.13060840
69SOX2_21211035_ChIP-Seq_LN229_Gbm1.11929577
70GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.10910870
71TET1_21490601_ChIP-Seq_MESCs_Mouse1.09630401
72STAT3_23295773_ChIP-Seq_U87_Human1.09203177
73TAF2_19829295_ChIP-Seq_ESCs_Human1.08567933
74NCOR_22424771_ChIP-Seq_293T_Human1.06898782
75GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.06781375
76CTCF_27219007_Chip-Seq_Bcells_Human1.05922866
77POU3F2_20337985_ChIP-ChIP_501MEL_Human1.05727064
78AR_25329375_ChIP-Seq_VCAP_Human1.04709522
79* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.03136665
80* ZFP281_27345836_Chip-Seq_ESCs_Mouse1.02660606
81TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.01844083
82NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse1.00928898
83* TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.00424095
84* RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.99905523
85OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.97950904
86TAF15_26573619_Chip-Seq_HEK293_Human0.97895985
87MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.95972828
88YAP1_20516196_ChIP-Seq_MESCs_Mouse0.95863975
89PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.95554502
90SMC4_20622854_ChIP-Seq_HELA_Human0.95473311
91SMAD3_21741376_ChIP-Seq_ESCs_Human0.95043686
92LXR_22292898_ChIP-Seq_THP-1_Human0.95043232
93* SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.94910960
94KLF4_19829295_ChIP-Seq_ESCs_Human0.94740549
95RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.94051843
96GATA3_21878914_ChIP-Seq_MCF-7_Human0.93650226
97TOP2B_26459242_ChIP-Seq_MCF-7_Human0.92893328
98MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.92627270
99TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91963376
100DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.91797293
101UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.91423897
102THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.91352560
103* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.88247044
104SMAD3_21741376_ChIP-Seq_EPCs_Human0.87654255
105OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.87457148
106CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.87064985
107SMAD4_21741376_ChIP-Seq_HESCs_Human0.86495418
108KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.85694433
109P300_19829295_ChIP-Seq_ESCs_Human0.85403783
110GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.85392324
111TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.85309811
112* KDM2B_26808549_Chip-Seq_SUP-B15_Human0.84969470
113SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.84437053
114TCF4_23295773_ChIP-Seq_U87_Human0.84067658
115ERA_21632823_ChIP-Seq_H3396_Human0.82653238
116FUS_26573619_Chip-Seq_HEK293_Human0.82599693
117MYC_19829295_ChIP-Seq_ESCs_Human0.82265058
118EST1_17652178_ChIP-ChIP_JURKAT_Human0.82112629
119TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.81790978
120FLI1_27457419_Chip-Seq_LIVER_Mouse0.80333551
121SMAD3_21741376_ChIP-Seq_HESCs_Human0.80232267
122SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.80192068
123* OCT4_19829295_ChIP-Seq_ESCs_Human0.79829322
124NANOG_19829295_ChIP-Seq_ESCs_Human0.79048151
125SOX2_19829295_ChIP-Seq_ESCs_Human0.79048151
126BCAT_22108803_ChIP-Seq_LS180_Human0.78707406
127NANOG_18555785_Chip-Seq_ESCs_Mouse0.77859507
128NR3C1_21868756_ChIP-Seq_MCF10A_Human0.77329922
129* SMAD4_21741376_ChIP-Seq_EPCs_Human0.77295567
130ZNF217_24962896_ChIP-Seq_MCF-7_Human0.77185659
131HTT_18923047_ChIP-ChIP_STHdh_Human0.77087461
132SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.76456710
133RXR_22108803_ChIP-Seq_LS180_Human0.76277524
134EWS_26573619_Chip-Seq_HEK293_Human0.76188689
135CBX2_27304074_Chip-Seq_ESCs_Mouse0.76132397
136TP53_20018659_ChIP-ChIP_R1E_Mouse0.74874686
137DPY_21335234_ChIP-Seq_ESCs_Mouse0.74428787
138* ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.74371443
139BMI1_23680149_ChIP-Seq_NPCS_Mouse0.74210327
140RNF2_27304074_Chip-Seq_NSC_Mouse0.73102528
141P53_22127205_ChIP-Seq_FIBROBLAST_Human0.72939138
142SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.72810125
143SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.72260804

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity7.71799726
2MP0003880_abnormal_central_pattern4.82827926
3MP0003635_abnormal_synaptic_transmissio4.27471048
4MP0004270_analgesia3.72561432
5MP0002063_abnormal_learning/memory/cond3.27647695
6MP0009745_abnormal_behavioral_response3.22998757
7MP0002064_seizures3.20410653
8MP0002272_abnormal_nervous_system2.78487482
9MP0009046_muscle_twitch2.76329506
10MP0002572_abnormal_emotion/affect_behav2.61852835
11MP0002909_abnormal_adrenal_gland2.58944116
12MP0001968_abnormal_touch/_nociception2.57864637
13MP0002734_abnormal_mechanical_nocicepti2.53589964
14MP0009780_abnormal_chondrocyte_physiolo2.51679637
15MP0005423_abnormal_somatic_nervous2.42097130
16MP0002735_abnormal_chemical_nociception2.38138147
17MP0002163_abnormal_gland_morphology2.35403830
18MP0001486_abnormal_startle_reflex2.34126628
19MP0008569_lethality_at_weaning2.28553812
20MP0001501_abnormal_sleep_pattern2.13759686
21MP0008877_abnormal_DNA_methylation2.12750204
22MP0002160_abnormal_reproductive_system2.11266561
23MP0001440_abnormal_grooming_behavior2.02204819
24MP0003195_calcinosis2.01438292
25MP0003121_genomic_imprinting1.97473833
26MP0002736_abnormal_nociception_after1.96439175
27MP0001970_abnormal_pain_threshold1.95219270
28MP0004858_abnormal_nervous_system1.94173844
29MP0003329_amyloid_beta_deposits1.90577978
30MP0002733_abnormal_thermal_nociception1.89879593
31MP0002067_abnormal_sensory_capabilities1.89658873
32MP0002876_abnormal_thyroid_physiology1.86527235
33MP0004811_abnormal_neuron_physiology1.84688779
34MP0003011_delayed_dark_adaptation1.83533178
35MP0003283_abnormal_digestive_organ1.80551473
36MP0000955_abnormal_spinal_cord1.80146695
37MP0002184_abnormal_innervation1.69344437
38MP0004885_abnormal_endolymph1.69312486
39MP0006292_abnormal_olfactory_placode1.67581687
40MP0004142_abnormal_muscle_tone1.65088306
41MP0003787_abnormal_imprinting1.59212114
42MP0002653_abnormal_ependyma_morphology1.58278876
43MP0005646_abnormal_pituitary_gland1.56445225
44MP0002557_abnormal_social/conspecific_i1.55426910
45MP0004043_abnormal_pH_regulation1.50007008
46MP0003633_abnormal_nervous_system1.48200357
47MP0002928_abnormal_bile_duct1.46566954
48MP0000778_abnormal_nervous_system1.46129617
49MP0005253_abnormal_eye_physiology1.45777943
50MP0003879_abnormal_hair_cell1.45627564
51MP0002938_white_spotting1.44917078
52MP0002066_abnormal_motor_capabilities/c1.44083946
53MP0002882_abnormal_neuron_morphology1.43930688
54MP0005389_reproductive_system_phenotype1.39219624
55MP0010386_abnormal_urinary_bladder1.38985940
56MP0005645_abnormal_hypothalamus_physiol1.36914193
57MP0006276_abnormal_autonomic_nervous1.33503863
58MP0005220_abnormal_exocrine_pancreas1.31169654
59MP0004145_abnormal_muscle_electrophysio1.27848785
60MP0000013_abnormal_adipose_tissue1.26247191
61MP0005386_behavior/neurological_phenoty1.24141521
62MP0004924_abnormal_behavior1.24141521
63MP0003122_maternal_imprinting1.23189492
64MP0004133_heterotaxia1.22757979
65MP0003890_abnormal_embryonic-extraembry1.21438534
66MP0009379_abnormal_foot_pigmentation1.19459102
67MP0003075_altered_response_to1.17410840
68MP0003631_nervous_system_phenotype1.16562749
69MP0008789_abnormal_olfactory_epithelium1.15405346
70MP0002822_catalepsy1.09886702
71MP0001529_abnormal_vocalization1.05754662
72MP0002229_neurodegeneration1.05107980
73MP0001756_abnormal_urination1.03906003
74MP0002693_abnormal_pancreas_physiology1.02405985
75MP0002152_abnormal_brain_morphology1.01938316
76MP0003172_abnormal_lysosome_physiology0.99329074
77MP0002069_abnormal_eating/drinking_beha0.94544094
78MP0003634_abnormal_glial_cell0.93414910
79MP0005535_abnormal_body_temperature0.91383580
80MP0001502_abnormal_circadian_rhythm0.91344564
81MP0001984_abnormal_olfaction0.91079935
82MP0008961_abnormal_basal_metabolism0.90401328
83MP0004134_abnormal_chest_morphology0.89500225
84MP0005448_abnormal_energy_balance0.89170794
85MP0001348_abnormal_lacrimal_gland0.88992619
86MP0002102_abnormal_ear_morphology0.88959420
87MP0004510_myositis0.88776654
88MP0000639_abnormal_adrenal_gland0.88611262
89MP0001944_abnormal_pancreas_morphology0.88455779
90MP0000372_irregular_coat_pigmentation0.87767480
91MP0002638_abnormal_pupillary_reflex0.87127474
92MP0000920_abnormal_myelination0.86394894
93MP0001485_abnormal_pinna_reflex0.86078814
94MP0001905_abnormal_dopamine_level0.85957453
95MP0005084_abnormal_gallbladder_morpholo0.85639422
96MP0000678_abnormal_parathyroid_gland0.85471165
97MP0003690_abnormal_glial_cell0.84674818
98MP0002090_abnormal_vision0.83755504
99MP0002234_abnormal_pharynx_morphology0.83704990
100MP0005195_abnormal_posterior_eye0.83171479
101MP0001919_abnormal_reproductive_system0.82718283
102MP0001963_abnormal_hearing_physiology0.80610042
103MP0003632_abnormal_nervous_system0.79583703
104MP0001765_abnormal_ion_homeostasis0.78679084
105MP0003123_paternal_imprinting0.77633260
106MP0002877_abnormal_melanocyte_morpholog0.75528843
107MP0003953_abnormal_hormone_level0.75336243
108MP0002837_dystrophic_cardiac_calcinosis0.75322999
109MP0000604_amyloidosis0.74246827
110MP0006072_abnormal_retinal_apoptosis0.72576426
111MP0001177_atelectasis0.71705230
112MP0005551_abnormal_eye_electrophysiolog0.69459630
113MP0004085_abnormal_heartbeat0.68409435
114MP0008872_abnormal_physiological_respon0.67125762
115MP0004215_abnormal_myocardial_fiber0.66831606
116MP0000751_myopathy0.65357662
117MP0003137_abnormal_impulse_conducting0.65290013
118MP0002752_abnormal_somatic_nervous0.65041021
119MP0005394_taste/olfaction_phenotype0.64694874
120MP0005499_abnormal_olfactory_system0.64694874
121MP0002078_abnormal_glucose_homeostasis0.64599159
122MP0000631_abnormal_neuroendocrine_gland0.64500409
123MP0004742_abnormal_vestibular_system0.62723402
124MP0001299_abnormal_eye_distance/0.62590974
125MP0001664_abnormal_digestion0.62072118
126MP0005379_endocrine/exocrine_gland_phen0.61822474
127MP0008874_decreased_physiological_sensi0.60483251
128MP0001188_hyperpigmentation0.60482935
129MP0001986_abnormal_taste_sensitivity0.57856328
130MP0004233_abnormal_muscle_weight0.57723945
131MP0003183_abnormal_peptide_metabolism0.57068888

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)7.89354139
2Focal motor seizures (HP:0011153)7.65539032
3Visual hallucinations (HP:0002367)5.89351562
4Hypoglycemic seizures (HP:0002173)5.27498215
5Focal seizures (HP:0007359)5.18389706
6Progressive cerebellar ataxia (HP:0002073)4.81140988
7Atonic seizures (HP:0010819)4.73786158
8Action tremor (HP:0002345)4.72180403
9Abnormal pancreas size (HP:0012094)4.50146166
10Febrile seizures (HP:0002373)4.27445529
11Ketoacidosis (HP:0001993)4.20377163
12Supranuclear gaze palsy (HP:0000605)4.18918596
13Absence seizures (HP:0002121)4.16952987
14Epileptic encephalopathy (HP:0200134)4.08794048
15Ventricular fibrillation (HP:0001663)4.02516594
16Hypoglycemic coma (HP:0001325)4.00235116
17Generalized tonic-clonic seizures (HP:0002069)3.90155566
18Dialeptic seizures (HP:0011146)3.83175739
19Depression (HP:0000716)3.69489614
20Abnormality of the lower motor neuron (HP:0002366)3.43404329
21Dysmetria (HP:0001310)3.40947080
22Impaired vibration sensation in the lower limbs (HP:0002166)3.39171976
23Symptomatic seizures (HP:0011145)3.35368315
24Acute necrotizing encephalopathy (HP:0006965)3.27452264
25Papilledema (HP:0001085)3.22213571
26Anxiety (HP:0000739)3.19253359
27Molar tooth sign on MRI (HP:0002419)3.15539047
28Abnormality of midbrain morphology (HP:0002418)3.15539047
29Bundle branch block (HP:0011710)3.14947088
30Elevated circulating parathyroid hormone (PTH) level (HP:0003165)3.14889135
31Ankle clonus (HP:0011448)3.13030471
32Progressive macrocephaly (HP:0004481)3.12105890
33Dysdiadochokinesis (HP:0002075)3.01843582
34Abnormality of the pancreatic islet cells (HP:0006476)3.01356480
35Abnormality of endocrine pancreas physiology (HP:0012093)3.01356480
36Gaze-evoked nystagmus (HP:0000640)3.01279585
37Abnormal eating behavior (HP:0100738)3.00234578
38Megalencephaly (HP:0001355)2.99892131
39Hepatoblastoma (HP:0002884)2.99714152
40Hemiplegia (HP:0002301)2.98560560
41Postural instability (HP:0002172)2.98138999
42Intention tremor (HP:0002080)2.95886840
43Neoplasm of the adrenal cortex (HP:0100641)2.95372899
44Hyperglycemia (HP:0003074)2.93177619
45Increased circulating renin level (HP:0000848)2.92914690
46Acute encephalopathy (HP:0006846)2.92457741
47Hyperthyroidism (HP:0000836)2.90062861
48Amblyopia (HP:0000646)2.89175863
49Impaired smooth pursuit (HP:0007772)2.88316487
50Mitochondrial inheritance (HP:0001427)2.87691704
51Prominent metopic ridge (HP:0005487)2.87038782
52Medial flaring of the eyebrow (HP:0010747)2.86157278
53Truncal ataxia (HP:0002078)2.85946152
54Ketosis (HP:0001946)2.85155368
55Abnormal mitochondria in muscle tissue (HP:0008316)2.84199454
56Methylmalonic acidemia (HP:0002912)2.79290639
57Poor eye contact (HP:0000817)2.78347793
58Metaphyseal dysplasia (HP:0100255)2.76029516
59Decreased circulating renin level (HP:0003351)2.71882436
60Broad-based gait (HP:0002136)2.70224367
61Insulin-resistant diabetes mellitus (HP:0000831)2.70196667
62Hypomagnesemia (HP:0002917)2.66464544
63Abnormality of the metopic suture (HP:0005556)2.64256072
64Nephronophthisis (HP:0000090)2.64162209
65Annular pancreas (HP:0001734)2.64037909
66Abnormal drinking behavior (HP:0030082)2.63513764
67Polydipsia (HP:0001959)2.63513764
68Increased hepatocellular lipid droplets (HP:0006565)2.63038651
69Hemiparesis (HP:0001269)2.61683024
70Bradykinesia (HP:0002067)2.59568869
71Mutism (HP:0002300)2.58555920
72Agitation (HP:0000713)2.58346432
73Increased CSF lactate (HP:0002490)2.58343382
74Abnormal social behavior (HP:0012433)2.57548632
75Impaired social interactions (HP:0000735)2.57548632
76Epileptiform EEG discharges (HP:0011182)2.57449184
77Adrenal hypoplasia (HP:0000835)2.57238050
78Polyphagia (HP:0002591)2.57198426
79Diplopia (HP:0000651)2.54971743
80Abnormality of binocular vision (HP:0011514)2.54971743
81Abnormality of magnesium homeostasis (HP:0004921)2.53501870
82Spastic gait (HP:0002064)2.52510639
83Insomnia (HP:0100785)2.50971178
84Gait imbalance (HP:0002141)2.50520300
85EEG with generalized epileptiform discharges (HP:0011198)2.46893882
86Enlarged penis (HP:0000040)2.44263986
87Abnormality of ocular smooth pursuit (HP:0000617)2.42433462
88Hypsarrhythmia (HP:0002521)2.41404672
89Hepatic necrosis (HP:0002605)2.40408957
90Late onset (HP:0003584)2.38529379
91Delusions (HP:0000746)2.34384102
92Congenital primary aphakia (HP:0007707)2.34380829
93Lipid accumulation in hepatocytes (HP:0006561)2.33071616
94Focal dystonia (HP:0004373)2.32236192
95Type I diabetes mellitus (HP:0100651)2.31643608
96Pheochromocytoma (HP:0002666)2.30180061
97Renal Fanconi syndrome (HP:0001994)2.28165001
98Hyperinsulinemic hypoglycemia (HP:0000825)2.27282569
99Genetic anticipation (HP:0003743)2.25474986
100Urinary urgency (HP:0000012)2.23691418
101Scanning speech (HP:0002168)2.22142513
102Drooling (HP:0002307)2.21238559
103Excessive salivation (HP:0003781)2.21238559
104Urinary bladder sphincter dysfunction (HP:0002839)2.20720616
105Pointed chin (HP:0000307)2.18246488
106Neurofibrillary tangles (HP:0002185)2.17631371
107Chronic hepatic failure (HP:0100626)2.16442406
108Nephrogenic diabetes insipidus (HP:0009806)2.16428037
109Impaired vibratory sensation (HP:0002495)2.16271095
110Abnormality of macular pigmentation (HP:0008002)2.15297048
111Hyperphosphatemia (HP:0002905)2.14878423
112Large for gestational age (HP:0001520)2.14743615
113Hepatocellular necrosis (HP:0001404)2.11852600
114Abnormality of the renal medulla (HP:0100957)2.11273215
115Hyperphosphaturia (HP:0003109)2.09393003
116Glycosuria (HP:0003076)2.08333338
117Abnormality of urine glucose concentration (HP:0011016)2.08333338
118Disproportionate short-trunk short stature (HP:0003521)2.07717818
119Cerebral inclusion bodies (HP:0100314)2.07243629
120Torticollis (HP:0000473)2.07208383
121Gait ataxia (HP:0002066)2.06330408
122Abnormal EKG (HP:0003115)2.03820207
123Deep palmar crease (HP:0006191)2.03816500
124Muscular hypotonia of the trunk (HP:0008936)2.02944408
125Progressive inability to walk (HP:0002505)2.02889175
126Stereotypic behavior (HP:0000733)2.02586842
127Fetal akinesia sequence (HP:0001989)2.02447844
128Neuroendocrine neoplasm (HP:0100634)2.00914296
129Vaginal atresia (HP:0000148)1.99265692
130Lower limb asymmetry (HP:0100559)1.97463616
131Genital tract atresia (HP:0001827)1.97276014
132Pancreatic fibrosis (HP:0100732)1.96812539
133Hypercortisolism (HP:0001578)1.96237495
134Methylmalonic aciduria (HP:0012120)1.96171393
135Obstructive sleep apnea (HP:0002870)1.95772415
136Abnormality of calcium-phosphate metabolism (HP:0100530)1.94933249
137Type II lissencephaly (HP:0007260)1.93394887
138Spinal canal stenosis (HP:0003416)1.91813271
139Cerebral edema (HP:0002181)1.90516891
140Abnormality of renin-angiotensin system (HP:0000847)1.90463783
141Abnormality of the labia minora (HP:0012880)1.89430155
142Congenital malformation of the right heart (HP:0011723)1.88988593
143Double outlet right ventricle (HP:0001719)1.88988593
144Diastasis recti (HP:0001540)1.88502809
145Pancreatic cysts (HP:0001737)1.88486202
146Rigidity (HP:0002063)1.88095364
147Psychosis (HP:0000709)1.87680557
148Rapidly progressive (HP:0003678)1.87661752
149Tubular atrophy (HP:0000092)1.86987231
150Optic nerve coloboma (HP:0000588)1.86550886
151Hyperventilation (HP:0002883)1.86304723
152Generalized myoclonic seizures (HP:0002123)1.85558878
153Failure to thrive in infancy (HP:0001531)1.84830382
154Abnormality of saccadic eye movements (HP:0000570)1.84395532
155Neuronal loss in central nervous system (HP:0002529)1.82976078
156Poor suck (HP:0002033)1.82694172
157Postural tremor (HP:0002174)1.82458891
158Anosmia (HP:0000458)1.82456752
159Incomplete penetrance (HP:0003829)1.80914794
160Unsteady gait (HP:0002317)1.80833238
1613-Methylglutaconic aciduria (HP:0003535)1.80354510
162Hypothermia (HP:0002045)1.80276072
163Clonus (HP:0002169)1.80090669
164Status epilepticus (HP:0002133)1.80058822
165Lower limb muscle weakness (HP:0007340)1.79732954
166Neonatal hypoglycemia (HP:0001998)1.79441638
167Abnormality of the renal cortex (HP:0011035)1.78182679
168Limb ataxia (HP:0002070)1.77607101
169Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.77294276
170Craniofacial dystonia (HP:0012179)1.77188451
171Amyotrophic lateral sclerosis (HP:0007354)1.76691412
172Aplasia/Hypoplasia of the spleen (HP:0010451)1.76555539
173Tetraplegia (HP:0002445)1.74968743
174Neoplasm of the peripheral nervous system (HP:0100007)1.74479076
175Abnormality of homocysteine metabolism (HP:0010919)1.73968614
176Homocystinuria (HP:0002156)1.73968614
177Abnormal urine phosphate concentration (HP:0012599)1.72291938
178Oligodactyly (hands) (HP:0001180)1.71817280
179Abnormal respiratory motile cilium physiology (HP:0012261)1.69287954
180Occipital encephalocele (HP:0002085)1.68957207

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK35.53632172
2FRK4.88274558
3STK164.46160918
4PASK4.18787686
5PRKD34.13537871
6MAP3K93.58406958
7EPHA43.31188442
8MINK13.20875457
9BMPR1B2.88922861
10FGFR22.57644150
11MAP3K42.49404833
12CAMKK12.38295660
13ADRBK22.33967998
14KSR22.33249447
15MAP4K22.23730387
16STK382.22918053
17PAK62.18101723
18TLK12.12306297
19MARK12.06905691
20MAP2K72.04148594
21MAP3K121.92331398
22UHMK11.78305914
23NTRK11.77437379
24ARAF1.69261044
25PRPF4B1.67015539
26MAP3K21.66122852
27MAP2K41.65641000
28GRK11.64226086
29CSNK1G21.56588224
30DAPK21.54397477
31LMTK21.54142680
32NME11.53041680
33CSNK1G31.49814184
34NTRK21.49658493
35DYRK21.49526236
36CDK51.49018243
37PRKCG1.43573190
38FES1.39456609
39CDK191.35344026
40GRK51.34349845
41KSR11.31933536
42CSNK1G11.30370591
43EPHA31.26421114
44PINK11.25922901
45CAMK2B1.24405790
46MAP3K11.18924275
47PRKCH1.17858056
48DAPK11.17456892
49TIE11.17307633
50RIPK41.16826561
51MAP3K131.15518580
52CAMK11.15246371
53CAMKK21.13703725
54BCKDK1.08703124
55CSNK1A1L1.08123690
56ALK1.02996647
57WNK11.01166847
58CAMK2A1.01070472
59PDK10.97985610
60NUAK10.96140636
61MAPK130.94985074
62TYRO30.94775388
63PNCK0.94654170
64PHKG10.94386702
65PHKG20.94386702
66CDC42BPA0.93216329
67BRSK10.91775468
68ACVR1B0.91707190
69INSRR0.89825972
70CDK90.89239357
71PLK20.86669220
72SGK2230.84615678
73SGK4940.84615678
74TRIM280.83463156
75LIMK10.82630771
76PDPK10.80212439
77STK110.80192446
78NEK60.79039111
79PAK30.78042324
80RAF10.77354718
81CDK150.77036151
82CDK140.76462658
83FER0.76333684
84CDK180.76276474
85LATS20.75665047
86CAMK2D0.74433577
87CAMK2G0.74033534
88ADRBK10.74017780
89CASK0.73968957
90SCYL20.73221800
91TNIK0.72836495
92RET0.72054322
93STK38L0.70428087
94PTK2B0.70137115
95CDK11A0.67360472
96DYRK1A0.67115792
97HIPK20.65401862
98PRKACA0.65013244
99CSNK1A10.60204606
100PRKD20.59235447
101BRAF0.58491657
102IRAK10.57442739
103MAP3K70.55680439
104NLK0.55177594
105SGK20.54598322
106MAPK100.53908184
107NEK10.53783774
108SGK30.53622428
109PRKG10.53371189
110PRKAA10.52273834
111SGK10.51550526
112MAP2K60.51433117
113ITK0.51213178
114ERBB20.51150123
115STK240.51095928
116PKN10.50478346
117MARK20.50187122
118RPS6KA30.47821440
119CAMK40.47565857
120TNK20.47539822
121TAOK10.47097546
122BMPR20.46403272
123WNK40.46323171
124PDGFRA0.45920945
125CAMK1G0.45644460
126SIK20.44378448
127PRKCE0.44073402
128PRKCZ0.42710851
129AKT30.41965784
130MST40.41607635
131OXSR10.39234503
132ABL20.38018173
133CSNK1E0.37091546
134PRKCA0.36384788
135FYN0.35740837
136CSNK1D0.34879390
137DYRK30.34153036
138MAP2K10.33084880
139PRKAA20.32733734
140RPS6KA20.32701460
141DDR20.32026217
142AURKA0.31970332
143ROCK20.31648458
144MAP3K110.31281898
145EPHB20.31174849
146WNK30.30728194
147PRKACG0.30262751
148PRKCQ0.30050717

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001903.57530132
2Nicotine addiction_Homo sapiens_hsa050333.38805665
3Synaptic vesicle cycle_Homo sapiens_hsa047213.31306407
4Long-term potentiation_Homo sapiens_hsa047203.05720244
5Protein export_Homo sapiens_hsa030602.88843761
6Insulin secretion_Homo sapiens_hsa049112.75740353
7Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.73184450
8Circadian entrainment_Homo sapiens_hsa047132.68291638
9Parkinsons disease_Homo sapiens_hsa050122.64567617
10Amphetamine addiction_Homo sapiens_hsa050312.59230594
11Glutamatergic synapse_Homo sapiens_hsa047242.55335873
12Olfactory transduction_Homo sapiens_hsa047402.53174443
13GABAergic synapse_Homo sapiens_hsa047272.52445157
14Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.46950758
15Regulation of autophagy_Homo sapiens_hsa041402.29565775
16Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.21489929
17Salivary secretion_Homo sapiens_hsa049702.17894625
18Morphine addiction_Homo sapiens_hsa050322.13703252
19Gastric acid secretion_Homo sapiens_hsa049712.13187134
20Aldosterone synthesis and secretion_Homo sapiens_hsa049252.08852575
21Dopaminergic synapse_Homo sapiens_hsa047282.05776976
22Ribosome_Homo sapiens_hsa030102.04387222
23Cholinergic synapse_Homo sapiens_hsa047251.99779068
24Butanoate metabolism_Homo sapiens_hsa006501.98918134
25Nitrogen metabolism_Homo sapiens_hsa009101.80800118
26Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.74742635
27Taste transduction_Homo sapiens_hsa047421.74585001
28Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.72104050
29Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.71543655
30Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.70713269
31Type II diabetes mellitus_Homo sapiens_hsa049301.68453696
32Long-term depression_Homo sapiens_hsa047301.68341229
33Huntingtons disease_Homo sapiens_hsa050161.65849239
34Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.62872059
35Calcium signaling pathway_Homo sapiens_hsa040201.56536724
36GnRH signaling pathway_Homo sapiens_hsa049121.53872505
37Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.51336052
38Oxytocin signaling pathway_Homo sapiens_hsa049211.50435486
39Maturity onset diabetes of the young_Homo sapiens_hsa049501.42495426
40Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.39349677
41Serotonergic synapse_Homo sapiens_hsa047261.35374058
42Phosphatidylinositol signaling system_Homo sapiens_hsa040701.34350992
43Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.29831384
44Cocaine addiction_Homo sapiens_hsa050301.29544677
45Renin secretion_Homo sapiens_hsa049241.29445792
46Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.28268639
47Pancreatic secretion_Homo sapiens_hsa049721.27604769
48cAMP signaling pathway_Homo sapiens_hsa040241.27072912
49Gap junction_Homo sapiens_hsa045401.24134451
50Glioma_Homo sapiens_hsa052141.23665273
51Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.21147763
52Collecting duct acid secretion_Homo sapiens_hsa049661.19058265
53Estrogen signaling pathway_Homo sapiens_hsa049151.17810525
54Melanogenesis_Homo sapiens_hsa049161.12905279
55Vibrio cholerae infection_Homo sapiens_hsa051101.08990337
56Carbohydrate digestion and absorption_Homo sapiens_hsa049731.08111279
57Sulfur metabolism_Homo sapiens_hsa009201.05151645
58cGMP-PKG signaling pathway_Homo sapiens_hsa040221.03843917
59Peroxisome_Homo sapiens_hsa041461.03305307
60Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.02767848
61Oocyte meiosis_Homo sapiens_hsa041141.02629616
62Fatty acid elongation_Homo sapiens_hsa000621.02451539
63Thyroid hormone synthesis_Homo sapiens_hsa049181.01323312
64ErbB signaling pathway_Homo sapiens_hsa040120.99577251
65Tryptophan metabolism_Homo sapiens_hsa003800.95824357
66Type I diabetes mellitus_Homo sapiens_hsa049400.95036787
67Ovarian steroidogenesis_Homo sapiens_hsa049130.94377651
68Vascular smooth muscle contraction_Homo sapiens_hsa042700.93620762
69Cardiac muscle contraction_Homo sapiens_hsa042600.89258456
70Sulfur relay system_Homo sapiens_hsa041220.85525042
71Phospholipase D signaling pathway_Homo sapiens_hsa040720.83058536
72Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.81948103
73Dorso-ventral axis formation_Homo sapiens_hsa043200.78228159
74Fatty acid metabolism_Homo sapiens_hsa012120.77950140
75Glucagon signaling pathway_Homo sapiens_hsa049220.77744596
76RNA degradation_Homo sapiens_hsa030180.77690363
77Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.76681370
78Choline metabolism in cancer_Homo sapiens_hsa052310.76093868
79VEGF signaling pathway_Homo sapiens_hsa043700.74401849
80RNA polymerase_Homo sapiens_hsa030200.73335397
81Axon guidance_Homo sapiens_hsa043600.72378479
82Linoleic acid metabolism_Homo sapiens_hsa005910.70777896
83Basal transcription factors_Homo sapiens_hsa030220.70702881
84alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.69503926
85Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.68791109
86Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.67997047
87mTOR signaling pathway_Homo sapiens_hsa041500.66572802
88Neurotrophin signaling pathway_Homo sapiens_hsa047220.65238347
89Endocytosis_Homo sapiens_hsa041440.65145596
90Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.64648593
91Inositol phosphate metabolism_Homo sapiens_hsa005620.61416852
92Propanoate metabolism_Homo sapiens_hsa006400.61190122
93Ether lipid metabolism_Homo sapiens_hsa005650.61050538
94Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.59496545
95Thyroid hormone signaling pathway_Homo sapiens_hsa049190.58867964
96Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.58485959
97MAPK signaling pathway_Homo sapiens_hsa040100.57852831
98Sphingolipid signaling pathway_Homo sapiens_hsa040710.56777619
99Fatty acid degradation_Homo sapiens_hsa000710.54780811
100SNARE interactions in vesicular transport_Homo sapiens_hsa041300.54097159
101Ras signaling pathway_Homo sapiens_hsa040140.50536097
102Selenocompound metabolism_Homo sapiens_hsa004500.50204352
103Prion diseases_Homo sapiens_hsa050200.50157519
104Retinol metabolism_Homo sapiens_hsa008300.50052709
105Dilated cardiomyopathy_Homo sapiens_hsa054140.49960304
106Glycerolipid metabolism_Homo sapiens_hsa005610.49296782
107Bile secretion_Homo sapiens_hsa049760.49015500
108Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.48648618
109Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.48092652
110Rap1 signaling pathway_Homo sapiens_hsa040150.47573766
111ABC transporters_Homo sapiens_hsa020100.47443132
112Sphingolipid metabolism_Homo sapiens_hsa006000.47433253
113Phototransduction_Homo sapiens_hsa047440.46669604
114Metabolic pathways_Homo sapiens_hsa011000.46253356
115Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.44775563
116Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.44466251
117Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.42417712
118Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.41419233
119Longevity regulating pathway - mammal_Homo sapiens_hsa042110.40325941
120Wnt signaling pathway_Homo sapiens_hsa043100.39653570
121Primary bile acid biosynthesis_Homo sapiens_hsa001200.39492648
122Insulin signaling pathway_Homo sapiens_hsa049100.39361110
123Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.38210157
124Alcoholism_Homo sapiens_hsa050340.36180063
125Steroid biosynthesis_Homo sapiens_hsa001000.35800132
126Circadian rhythm_Homo sapiens_hsa047100.34398465
127Non-small cell lung cancer_Homo sapiens_hsa052230.34316909
128Vitamin digestion and absorption_Homo sapiens_hsa049770.33749134
129Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.31464474
130Endometrial cancer_Homo sapiens_hsa052130.31216113
131Caffeine metabolism_Homo sapiens_hsa002320.31033419
132Fat digestion and absorption_Homo sapiens_hsa049750.30619190
133Hedgehog signaling pathway_Homo sapiens_hsa043400.30494538
134Arachidonic acid metabolism_Homo sapiens_hsa005900.29560053
135Chemical carcinogenesis_Homo sapiens_hsa052040.29496018
136Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.29369684
137Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.29312410
138Alzheimers disease_Homo sapiens_hsa050100.28609474
139Glycerophospholipid metabolism_Homo sapiens_hsa005640.26576936
140Prolactin signaling pathway_Homo sapiens_hsa049170.25069300
141African trypanosomiasis_Homo sapiens_hsa051430.23323741
142Lysosome_Homo sapiens_hsa041420.22750949
143Renal cell carcinoma_Homo sapiens_hsa052110.20731954
144Mineral absorption_Homo sapiens_hsa049780.20239610
145Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.20109589
146Central carbon metabolism in cancer_Homo sapiens_hsa052300.19368353

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »