CACHD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1lateral sprouting from an epithelium (GO:0060601)6.11149586
2planar cell polarity pathway involved in neural tube closure (GO:0090179)4.26164806
3presynaptic membrane assembly (GO:0097105)4.01102445
4regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.93083362
5limb bud formation (GO:0060174)3.83717217
6regulation of gene silencing by RNA (GO:0060966)3.76536473
7regulation of posttranscriptional gene silencing (GO:0060147)3.76536473
8regulation of gene silencing by miRNA (GO:0060964)3.76536473
9head development (GO:0060322)3.70381741
10G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071993.68417542
11pre-miRNA processing (GO:0031054)3.59237609
12negative regulation of axon extension involved in axon guidance (GO:0048843)3.56215214
13presynaptic membrane organization (GO:0097090)3.47801797
14central nervous system myelination (GO:0022010)3.45486595
15axon ensheathment in central nervous system (GO:0032291)3.45486595
16paraxial mesoderm development (GO:0048339)3.40174765
17bone trabecula formation (GO:0060346)3.39418282
18Wnt signaling pathway, planar cell polarity pathway (GO:0060071)3.36393066
19regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)3.35636625
20cerebral cortex radially oriented cell migration (GO:0021799)3.34512699
21non-canonical Wnt signaling pathway (GO:0035567)3.32999227
22outer ear morphogenesis (GO:0042473)3.31537641
23axonal fasciculation (GO:0007413)3.28132137
24establishment of tissue polarity (GO:0007164)3.27908658
25establishment of planar polarity (GO:0001736)3.27908658
26regulation of branching involved in prostate gland morphogenesis (GO:0060687)3.25931755
27negative regulation of axon guidance (GO:1902668)3.22055489
28regulation of establishment of planar polarity (GO:0090175)3.20159653
29epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)3.19622831
30hippo signaling (GO:0035329)3.12219545
31regulation of cell fate specification (GO:0042659)3.09826284
32mesenchymal cell proliferation (GO:0010463)3.09533574
33negative regulation of catenin import into nucleus (GO:0035414)3.08348508
34dorsal/ventral axis specification (GO:0009950)3.08345819
35notochord development (GO:0030903)3.08108000
36convergent extension (GO:0060026)3.08002077
37regulation of axon extension involved in axon guidance (GO:0048841)3.07076685
38neuron recognition (GO:0008038)3.06966916
39prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:0060523.06126579
40mesenchymal-epithelial cell signaling (GO:0060638)3.05201897
41cochlea morphogenesis (GO:0090103)3.04203962
42postsynaptic membrane organization (GO:0001941)3.02697030
43mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)3.00735134
44regulation of non-canonical Wnt signaling pathway (GO:2000050)2.95358687
45tongue development (GO:0043586)2.94847101
46hindlimb morphogenesis (GO:0035137)2.93227036
47apical protein localization (GO:0045176)2.92322445
48otic vesicle formation (GO:0030916)2.92018544
49negative regulation of embryonic development (GO:0045992)2.91564376
50regulation of axon guidance (GO:1902667)2.90754337
51negative regulation of translation, ncRNA-mediated (GO:0040033)2.89920202
52regulation of translation, ncRNA-mediated (GO:0045974)2.89920202
53negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.89920202
54heterochromatin organization (GO:0070828)2.88986216
55midbrain development (GO:0030901)2.86931583
56neuronal stem cell maintenance (GO:0097150)2.83850648
57cell surface receptor signaling pathway involved in heart development (GO:0061311)2.83808163
58anterior/posterior axis specification, embryo (GO:0008595)2.81372008
59lung-associated mesenchyme development (GO:0060484)2.81258505
60cell proliferation in forebrain (GO:0021846)2.78869538
61regulation of mesoderm development (GO:2000380)2.77020143
62craniofacial suture morphogenesis (GO:0097094)2.75625118
63negative regulation of smoothened signaling pathway (GO:0045879)2.75151128
64embryonic forelimb morphogenesis (GO:0035115)2.74231815
65artery development (GO:0060840)2.73709996
66positive regulation of SMAD protein import into nucleus (GO:0060391)2.73262591
67forelimb morphogenesis (GO:0035136)2.72727843
68neuron projection extension involved in neuron projection guidance (GO:1902284)2.70986141
69axon extension involved in axon guidance (GO:0048846)2.70986141
70dendritic spine morphogenesis (GO:0060997)2.70807942
71polarized epithelial cell differentiation (GO:0030859)2.70720962
72embryonic hindlimb morphogenesis (GO:0035116)2.69547936
73regulation of somitogenesis (GO:0014807)2.66939042
74developmental induction (GO:0031128)2.65444548
75pyrimidine nucleobase catabolic process (GO:0006208)2.65106085
76somatic stem cell division (GO:0048103)2.64567454
77digestive tract morphogenesis (GO:0048546)2.63541129
78cell-cell signaling involved in cell fate commitment (GO:0045168)2.63222404
79glomerulus development (GO:0032835)2.61599727
80anterior/posterior axis specification (GO:0009948)2.61150939
81central nervous system projection neuron axonogenesis (GO:0021952)2.60455898
82post-anal tail morphogenesis (GO:0036342)2.60115529
83mesenchyme morphogenesis (GO:0072132)2.59640154
84cell proliferation involved in metanephros development (GO:0072203)2.58931252
85cardiac epithelial to mesenchymal transition (GO:0060317)2.58710113
86generation of neurons (GO:0048699)2.58120018
87body morphogenesis (GO:0010171)2.58101429
88neuron cell-cell adhesion (GO:0007158)2.58099939
89layer formation in cerebral cortex (GO:0021819)2.57552487
90gastrulation with mouth forming second (GO:0001702)2.57504579
91proximal/distal pattern formation (GO:0009954)2.57384310
92regulation of catenin import into nucleus (GO:0035412)2.55805421
93mesenchymal to epithelial transition (GO:0060231)2.55060445
94retina layer formation (GO:0010842)2.54992598
95branching involved in salivary gland morphogenesis (GO:0060445)2.54490936
96negative regulation of astrocyte differentiation (GO:0048712)2.53731028
97positive regulation of catenin import into nucleus (GO:0035413)2.53497450
98metanephric mesenchyme development (GO:0072075)2.52531452
99regulation of smoothened signaling pathway (GO:0008589)2.50372181
100cell migration involved in gastrulation (GO:0042074)2.50370914
101endocardial cushion morphogenesis (GO:0003203)2.49882599
102camera-type eye morphogenesis (GO:0048593)2.49505963
103asymmetric protein localization (GO:0008105)2.48832714
104chondrocyte development (GO:0002063)2.48566268
105regulation of mesenchymal cell proliferation (GO:0010464)2.48412396
106cell migration in hindbrain (GO:0021535)2.47874202
107kidney mesenchyme development (GO:0072074)2.47849483
108ephrin receptor signaling pathway (GO:0048013)2.47828472
109positive regulation of smoothened signaling pathway (GO:0045880)2.47500944
110organ induction (GO:0001759)2.46697003
111atrial cardiac muscle cell action potential (GO:0086014)2.46525263
112regulation of Wnt signaling pathway involved in heart development (GO:0003307)2.46144695
113establishment of integrated proviral latency (GO:0075713)2.45655168
114positive regulation of mesenchymal cell proliferation (GO:0002053)2.45088681
115establishment of nucleus localization (GO:0040023)2.43768023
116somite development (GO:0061053)2.43667514
117negative regulation of cell fate specification (GO:0009996)2.43246338
118forebrain neuron development (GO:0021884)2.42954120
119positive regulation of gastrulation (GO:2000543)2.41980917
120spinal cord development (GO:0021510)2.41729648
121embryonic digit morphogenesis (GO:0042733)2.41343908
122establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.41096147
123negative regulation of chondrocyte differentiation (GO:0032331)2.41005499
124regulation of mesenchymal cell apoptotic process (GO:2001053)2.40793576
125retinal ganglion cell axon guidance (GO:0031290)2.39530349
126kidney morphogenesis (GO:0060993)2.39526410
127bone morphogenesis (GO:0060349)2.39521377
128chondrocyte proliferation (GO:0035988)2.39313739
129myelination in peripheral nervous system (GO:0022011)2.39132712
130peripheral nervous system axon ensheathment (GO:0032292)2.39132712
131embryonic foregut morphogenesis (GO:0048617)2.38678127
132mesonephros development (GO:0001823)2.38607549
133organ growth (GO:0035265)2.37247017
134nuclear pore complex assembly (GO:0051292)2.36865543
135radial glial cell differentiation (GO:0060019)2.36619901
136thalamus development (GO:0021794)2.35742108
137neural tube closure (GO:0001843)2.35288731
138tube closure (GO:0060606)2.34507431
139regulation of development, heterochronic (GO:0040034)2.33439088
140chromatin remodeling at centromere (GO:0031055)2.31584341
141mesenchymal cell differentiation (GO:0048762)2.29857604
142olfactory bulb development (GO:0021772)2.29307948
143limb development (GO:0060173)2.29092357
144appendage development (GO:0048736)2.29092357
145positive regulation of neuroblast proliferation (GO:0002052)2.27920709
146negative chemotaxis (GO:0050919)2.27141111
147cellular response to cholesterol (GO:0071397)2.25184482
148inner ear receptor cell development (GO:0060119)2.24567602
149primitive streak formation (GO:0090009)2.24214578
150regulation of cell fate commitment (GO:0010453)2.23255122
151neuron fate determination (GO:0048664)2.22930911
152cell migration involved in sprouting angiogenesis (GO:0002042)2.20089663
153regulation of heart morphogenesis (GO:2000826)2.19936339

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.06464914
2* JARID2_20064375_ChIP-Seq_MESCs_Mouse2.86998039
3EED_16625203_ChIP-ChIP_MESCs_Mouse2.85197102
4* EZH2_27304074_Chip-Seq_ESCs_Mouse2.85138389
5* SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.65464827
6* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.64522527
7* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.64522527
8GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.61721005
9E2F7_22180533_ChIP-Seq_HELA_Human2.56959991
10SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.54861549
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.50416276
12* SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.46722708
13SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.41388669
14GBX2_23144817_ChIP-Seq_PC3_Human2.36072900
15PHC1_16625203_ChIP-ChIP_MESCs_Mouse2.35885195
16* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.33662112
17CBX2_27304074_Chip-Seq_ESCs_Mouse2.30396667
18RNF2_27304074_Chip-Seq_ESCs_Mouse2.20388061
19RNF2_16625203_ChIP-ChIP_MESCs_Mouse2.19593631
20HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.18481256
21NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.16265842
22BMI1_23680149_ChIP-Seq_NPCS_Mouse2.04847723
23ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.98637416
24* MTF2_20144788_ChIP-Seq_MESCs_Mouse1.90315116
25RBPJ_22232070_ChIP-Seq_NCS_Mouse1.89991111
26POU5F1_16153702_ChIP-ChIP_HESCs_Human1.86643998
27TP63_17297297_ChIP-ChIP_HaCaT_Human1.84708131
28EZH2_27294783_Chip-Seq_ESCs_Mouse1.83965197
29AR_21572438_ChIP-Seq_LNCaP_Human1.83357969
30STAT6_21828071_ChIP-Seq_BEAS2B_Human1.82485294
31FOXM1_23109430_ChIP-Seq_U2OS_Human1.78027693
32CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.77134108
33* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.75221161
34* RING1B_27294783_Chip-Seq_NPCs_Mouse1.67147701
35EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.65954687
36* TP53_20018659_ChIP-ChIP_R1E_Mouse1.65556525
37* PIAS1_25552417_ChIP-Seq_VCAP_Human1.64603053
38CTBP2_25329375_ChIP-Seq_LNCAP_Human1.60873711
39NANOG_16153702_ChIP-ChIP_HESCs_Human1.59500603
40TRIM28_21343339_ChIP-Seq_HEK293_Human1.57801784
41* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.57720339
42RING1B_27294783_Chip-Seq_ESCs_Mouse1.57079496
43GATA1_26923725_Chip-Seq_HPCs_Mouse1.52538829
44SOX2_18555785_ChIP-Seq_MESCs_Mouse1.50860617
45RNF2_27304074_Chip-Seq_NSC_Mouse1.50568862
46WT1_19549856_ChIP-ChIP_CCG9911_Human1.50111204
47* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.47074230
48ERG_21242973_ChIP-ChIP_JURKAT_Human1.46521222
49PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.43884803
50CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.42574803
51* CTBP1_25329375_ChIP-Seq_LNCAP_Human1.40566088
52POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.40506219
53CDX2_19796622_ChIP-Seq_MESCs_Mouse1.40100826
54* TCF3_18692474_ChIP-Seq_MESCs_Mouse1.39528418
55POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.39496231
56E2F4_17652178_ChIP-ChIP_JURKAT_Human1.39324334
57SALL1_21062744_ChIP-ChIP_HESCs_Human1.39046473
58* ISL1_27105846_Chip-Seq_CPCs_Mouse1.37546942
59* FUS_26573619_Chip-Seq_HEK293_Human1.36763365
60ZNF217_24962896_ChIP-Seq_MCF-7_Human1.36430325
61* SMAD3_21741376_ChIP-Seq_EPCs_Human1.33951859
62TP53_18474530_ChIP-ChIP_U2OS_Human1.33583005
63SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.32516004
64TP63_19390658_ChIP-ChIP_HaCaT_Human1.31299306
65* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.30366958
66* P300_19829295_ChIP-Seq_ESCs_Human1.30154134
67WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.29944493
68VDR_22108803_ChIP-Seq_LS180_Human1.29529784
69TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.28633579
70NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.28057228
71TOP2B_26459242_ChIP-Seq_MCF-7_Human1.27700066
72SOX9_26525672_Chip-Seq_HEART_Mouse1.27420603
73* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.27326496
74ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.26101530
75IGF1R_20145208_ChIP-Seq_DFB_Human1.25586086
76ZFP57_27257070_Chip-Seq_ESCs_Mouse1.24691535
77ARNT_22903824_ChIP-Seq_MCF-7_Human1.23891770
78AHR_22903824_ChIP-Seq_MCF-7_Human1.22960184
79HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.22835999
80NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.21381200
81STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.21364682
82TAF15_26573619_Chip-Seq_HEK293_Human1.19021039
83SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.17462514
84RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.17450158
85* NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.17197189
86KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.17092528
87KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.17092528
88KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.17092528
89POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.16330717
90TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.16330717
91WT1_25993318_ChIP-Seq_PODOCYTE_Human1.16113467
92SMAD4_21799915_ChIP-Seq_A2780_Human1.15615818
93* TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.15085485
94TP53_16413492_ChIP-PET_HCT116_Human1.14650543
95* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.14332075
96KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.14180281
97* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.13449686
98EWS_26573619_Chip-Seq_HEK293_Human1.12964329
99ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.12838404
100AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.12355605
101E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.12098190
102* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11647675
103TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.10782809
104EP300_21415370_ChIP-Seq_HL-1_Mouse1.10465345
105SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.09715883
106DROSHA_22980978_ChIP-Seq_HELA_Human1.08749367
107POU3F2_20337985_ChIP-ChIP_501MEL_Human1.08698227
108SOX2_16153702_ChIP-ChIP_HESCs_Human1.08389314
109* LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07459700
110* YAP1_20516196_ChIP-Seq_MESCs_Mouse1.06180306
111* SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.04528502
112SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.04336623
113CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04072065
114ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.04006480
115PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.03269152
116SMAD3_21741376_ChIP-Seq_ESCs_Human1.02798045
117GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00756657
118NR3C1_21868756_ChIP-Seq_MCF10A_Human1.00612814
119ZNF274_21170338_ChIP-Seq_K562_Hela1.00182333
120CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.99722407
121TBX3_20139965_ChIP-Seq_ESCs_Mouse0.99033877
122UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.98901499
123TBX3_20139965_ChIP-Seq_MESCs_Mouse0.98806470
124TCF4_18268006_ChIP-ChIP_LS174T_Human0.98726936
125TCF3_18692474_ChIP-Seq_MEFs_Mouse0.95478582
126BCAT_22108803_ChIP-Seq_LS180_Human0.94634228
127TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.94602937

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010030_abnormal_orbit_morphology3.30455063
2MP0000566_synostosis3.06195017
3MP0000537_abnormal_urethra_morphology2.51350386
4MP0000049_abnormal_middle_ear2.28034972
5MP0009250_abnormal_appendicular_skeleto2.24529257
6MP0003122_maternal_imprinting2.18572489
7MP0003385_abnormal_body_wall2.18294595
8MP0003937_abnormal_limbs/digits/tail_de2.16491647
9MP0003941_abnormal_skin_development2.16088179
10MP0002249_abnormal_larynx_morphology2.13767710
11MP0000778_abnormal_nervous_system2.12272435
12MP0003942_abnormal_urinary_system2.10804096
13MP0009053_abnormal_anal_canal1.99200967
14MP0002938_white_spotting1.96318930
15MP0003938_abnormal_ear_development1.89027526
16MP0000762_abnormal_tongue_morphology1.83210473
17MP0003755_abnormal_palate_morphology1.77493032
18MP0003890_abnormal_embryonic-extraembry1.72579025
19MP0004272_abnormal_basement_membrane1.71118537
20MP0003880_abnormal_central_pattern1.67356227
21MP0009384_cardiac_valve_regurgitation1.60856543
22MP0002233_abnormal_nose_morphology1.60779815
23MP0000534_abnormal_ureter_morphology1.59470813
24MP0000428_abnormal_craniofacial_morphol1.58163425
25MP0002932_abnormal_joint_morphology1.57483302
26MP0005423_abnormal_somatic_nervous1.55889792
27MP0003123_paternal_imprinting1.51922384
28MP0008789_abnormal_olfactory_epithelium1.49272543
29MP0002116_abnormal_craniofacial_bone1.48814467
30MP0003121_genomic_imprinting1.47620878
31MP0001299_abnormal_eye_distance/1.45021209
32MP0005394_taste/olfaction_phenotype1.43882884
33MP0005499_abnormal_olfactory_system1.43882884
34MP0004133_heterotaxia1.42438402
35MP0002282_abnormal_trachea_morphology1.42032576
36MP0005623_abnormal_meninges_morphology1.36360458
37MP0009672_abnormal_birth_weight1.36004845
38MP0003935_abnormal_craniofacial_develop1.35751367
39MP0003567_abnormal_fetal_cardiomyocyte1.32851565
40MP0000462_abnormal_digestive_system1.32507450
41MP0000432_abnormal_head_morphology1.32180247
42MP0002102_abnormal_ear_morphology1.32098680
43MP0003861_abnormal_nervous_system1.31281388
44MP0003119_abnormal_digestive_system1.31063487
45MP0003283_abnormal_digestive_organ1.30926971
46MP0000383_abnormal_hair_follicle1.30053039
47MP0001293_anophthalmia1.29854087
48MP0004858_abnormal_nervous_system1.29552937
49MP0003136_yellow_coat_color1.28664946
50MP0002234_abnormal_pharynx_morphology1.27891018
51MP0000579_abnormal_nail_morphology1.26477834
52MP0005248_abnormal_Harderian_gland1.25626983
53MP0001346_abnormal_lacrimal_gland1.22545833
54MP0003315_abnormal_perineum_morphology1.21307331
55MP0000026_abnormal_inner_ear1.21202078
56MP0001340_abnormal_eyelid_morphology1.18577275
57MP0008932_abnormal_embryonic_tissue1.18320131
58MP0002111_abnormal_tail_morphology1.16557592
59MP0001486_abnormal_startle_reflex1.15588374
60MP0009379_abnormal_foot_pigmentation1.14851827
61MP0006292_abnormal_olfactory_placode1.14738219
62MP0008438_abnormal_cutaneous_collagen1.14301707
63MP0004885_abnormal_endolymph1.14031448
64MP0003115_abnormal_respiratory_system1.13285791
65MP0001984_abnormal_olfaction1.13284891
66MP0004859_abnormal_synaptic_plasticity1.13044711
67MP0004270_analgesia1.12332114
68MP0005171_absent_coat_pigmentation1.11543847
69MP0002653_abnormal_ependyma_morphology1.11496712
70MP0005508_abnormal_skeleton_morphology1.11433961
71MP0005187_abnormal_penis_morphology1.11036063
72MP0005503_abnormal_tendon_morphology1.10915213
73MP0009703_decreased_birth_body1.10818767
74MP0005391_vision/eye_phenotype1.09912695
75MP0002177_abnormal_outer_ear1.09841365
76MP0010678_abnormal_skin_adnexa1.09439811
77MP0000516_abnormal_urinary_system1.08956701
78MP0005367_renal/urinary_system_phenotyp1.08956701
79MP0001485_abnormal_pinna_reflex1.06333545
80MP0002114_abnormal_axial_skeleton1.04878355
81MP0001286_abnormal_eye_development1.02962923
82MP0002184_abnormal_innervation1.02219967
83MP0002254_reproductive_system_inflammat1.01638263
84MP0002109_abnormal_limb_morphology1.00049055
85MP0004957_abnormal_blastocyst_morpholog0.99743232
86MP0000631_abnormal_neuroendocrine_gland0.99288842
87MP0001529_abnormal_vocalization0.96240073
88MP0000163_abnormal_cartilage_morphology0.94879837
89MP0002152_abnormal_brain_morphology0.94622684
90MP0006072_abnormal_retinal_apoptosis0.94513648
91MP0000467_abnormal_esophagus_morphology0.94433262
92MP0000647_abnormal_sebaceous_gland0.94145537
93MP0001177_atelectasis0.92720356
94MP0003635_abnormal_synaptic_transmissio0.92363873
95MP0002697_abnormal_eye_size0.92320580
96MP0000955_abnormal_spinal_cord0.89150218
97MP0002752_abnormal_somatic_nervous0.86281836
98MP0002081_perinatal_lethality0.85713826
99MP0005380_embryogenesis_phenotype0.84991559
100MP0001672_abnormal_embryogenesis/_devel0.84991559
101MP0005377_hearing/vestibular/ear_phenot0.84859756
102MP0003878_abnormal_ear_physiology0.84859756
103MP0005257_abnormal_intraocular_pressure0.83706927
104MP0004197_abnormal_fetal_growth/weight/0.82761430
105MP0002882_abnormal_neuron_morphology0.82511337
106MP0002108_abnormal_muscle_morphology0.82413757
107MP0003705_abnormal_hypodermis_morpholog0.81746641
108MP0002557_abnormal_social/conspecific_i0.81162036
109MP0002751_abnormal_autonomic_nervous0.80785022
110MP0002098_abnormal_vibrissa_morphology0.80768919
111MP0002085_abnormal_embryonic_tissue0.80538092
112MP0005197_abnormal_uvea_morphology0.80374463
113MP0006276_abnormal_autonomic_nervous0.79955158
114MP0002092_abnormal_eye_morphology0.78863374
115MP0002084_abnormal_developmental_patter0.78625234
116MP0001188_hyperpigmentation0.78007017
117MP0001849_ear_inflammation0.77727484
118MP0002638_abnormal_pupillary_reflex0.75868934
119MP0010368_abnormal_lymphatic_system0.75805329
120MP0003984_embryonic_growth_retardation0.75386916

Predicted human phenotypes

RankGene SetZ-score
1Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.62433867
2Short 4th metacarpal (HP:0010044)3.62433867
3Aplasia involving bones of the extremities (HP:0009825)3.07481611
4Aplasia involving bones of the upper limbs (HP:0009823)3.07481611
5Aplasia of the phalanges of the hand (HP:0009802)3.07481611
6Coronal craniosynostosis (HP:0004440)3.03104753
7Abnormality of the nasolacrimal system (HP:0000614)2.93839456
8Midline defect of the nose (HP:0004122)2.91111488
9Abnormality of the 4th metacarpal (HP:0010012)2.89972744
10Colon cancer (HP:0003003)2.87013606
11Shallow orbits (HP:0000586)2.85278327
12Abnormality of the lacrimal duct (HP:0011481)2.84942257
13Abnormality of the parietal bone (HP:0002696)2.77746444
14Cutaneous finger syndactyly (HP:0010554)2.76673900
15Partial duplication of the phalanx of hand (HP:0009999)2.58957831
16Nasolacrimal duct obstruction (HP:0000579)2.55034995
17Anophthalmia (HP:0000528)2.49744384
18Concave nail (HP:0001598)2.48492950
19Preaxial foot polydactyly (HP:0001841)2.46094086
20Alacrima (HP:0000522)2.45577873
21Abnormality of the middle phalanges of the toes (HP:0010183)2.45361547
22Cutaneous syndactyly (HP:0012725)2.44963450
23Bilateral microphthalmos (HP:0007633)2.40496169
24Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658)2.38880327
25Morphological abnormality of the middle ear (HP:0008609)2.36041886
26Vitreoretinal degeneration (HP:0000655)2.35743876
27High anterior hairline (HP:0009890)2.34523936
28Maternal diabetes (HP:0009800)2.33326492
29Broad toe (HP:0001837)2.32717035
30Cortical dysplasia (HP:0002539)2.31758870
31Short middle phalanx of the 5th finger (HP:0004220)2.30762130
32Renal duplication (HP:0000075)2.29938530
33Bifid tongue (HP:0010297)2.26322895
34Abnormal number of incisors (HP:0011064)2.24611040
35Abnormality of the phalanges of the 2nd finger (HP:0009541)2.24013468
36Synostosis involving the elbow (HP:0003938)2.23990424
37Humeroradial synostosis (HP:0003041)2.23990424
38Absent septum pellucidum (HP:0001331)2.21373892
39Partial duplication of thumb phalanx (HP:0009944)2.17888951
40Abnormal lung lobation (HP:0002101)2.16339177
41Abnormality of the septum pellucidum (HP:0007375)2.14814215
42Hepatoblastoma (HP:0002884)2.12716019
43Microglossia (HP:0000171)2.12451832
44Choanal stenosis (HP:0000452)2.10806139
45Bronchomalacia (HP:0002780)2.10055994
46Supernumerary ribs (HP:0005815)2.07452843
47Myelomeningocele (HP:0002475)2.06503503
48Abnormality of the 2nd finger (HP:0004100)2.05092511
49Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)2.04655111
50Duplication of thumb phalanx (HP:0009942)2.04637686
51Megalencephaly (HP:0001355)2.04085501
52Abnormality of the middle phalanx of the 5th finger (HP:0004219)2.03787841
53Trigonocephaly (HP:0000243)2.02954726
54Hypoplastic labia majora (HP:0000059)2.02540411
55Gastrointestinal atresia (HP:0002589)2.02082189
56Optic nerve hypoplasia (HP:0000609)2.01774062
57Long nose (HP:0003189)1.99694356
58Abnormality of the distal phalanx of the thumb (HP:0009617)1.99149934
59Ectopic anus (HP:0004397)1.99129186
60Split foot (HP:0001839)1.99082018
61Broad thumb (HP:0011304)1.98421062
62Aplasia/Hypoplasia of the sternum (HP:0006714)1.97485464
63Abnormality of abdominal situs (HP:0011620)1.96383307
64Abdominal situs inversus (HP:0003363)1.96383307
65Buphthalmos (HP:0000557)1.95296192
66Rib fusion (HP:0000902)1.93517021
67Abnormality of the nasal septum (HP:0000419)1.92324284
68Abnormality of the phalanges of the hallux (HP:0010057)1.92051638
69Decreased lacrimation (HP:0000633)1.91932869
70Short hallux (HP:0010109)1.91509185
71Supernumerary bones of the axial skeleton (HP:0009144)1.90776373
72Abnormality of the labia minora (HP:0012880)1.87598730
73Intestinal atresia (HP:0011100)1.86263102
74Anteriorly placed anus (HP:0001545)1.86198682
75Abnormality of the phalanges of the 5th finger (HP:0004213)1.85686966
76Aplasia cutis congenita (HP:0001057)1.85188609
77Neonatal short-limb short stature (HP:0008921)1.85074819
78Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)1.83465150
79Abnormality of the aortic arch (HP:0012303)1.82075874
80Broad hallux (HP:0010055)1.82029750
81Abnormality of the labia majora (HP:0012881)1.81178853
82Absent eyebrow (HP:0002223)1.81128146
83Esophageal atresia (HP:0002032)1.80986580
84Broad metatarsal (HP:0001783)1.80076219
85Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.79327977
86Cupped ear (HP:0000378)1.79049555
87Renal hypoplasia (HP:0000089)1.78993290
88Short phalanx of the thumb (HP:0009660)1.78601814
89Abnormality of the antihelix (HP:0009738)1.78501582
902-3 toe syndactyly (HP:0004691)1.78495928
91Hemivertebrae (HP:0002937)1.78482410
92Wide anterior fontanel (HP:0000260)1.77309454
93Increased number of teeth (HP:0011069)1.76793516
94Mixed hearing impairment (HP:0000410)1.74917510
95Synostosis of carpal bones (HP:0005048)1.73878350
96Down-sloping shoulders (HP:0200021)1.73417120
97Vaginal atresia (HP:0000148)1.73297512
98Abnormality of the incisor (HP:0000676)1.72948688
99Natal tooth (HP:0000695)1.72790796
100Abnormality of the middle phalanges of the hand (HP:0009833)1.71630886
101Abnormal ciliary motility (HP:0012262)1.70358040
102Facial cleft (HP:0002006)1.69910976
103Turricephaly (HP:0000262)1.69201308
104Septo-optic dysplasia (HP:0100842)1.69176003
105Stenosis of the external auditory canal (HP:0000402)1.69000356
106Absent radius (HP:0003974)1.68439836
107Genital tract atresia (HP:0001827)1.67410195
108Omphalocele (HP:0001539)1.67309875
109Fibular aplasia (HP:0002990)1.66130233
110Spastic diplegia (HP:0001264)1.66060711
111Broad finger (HP:0001500)1.65788188
112Aplasia/Hypoplasia of the hallux (HP:0008362)1.65233119
113Skull defect (HP:0001362)1.65056666
114Mesomelia (HP:0003027)1.64582659
115Symphalangism affecting the phalanges of the hand (HP:0009773)1.64164454
116Supernumerary spleens (HP:0009799)1.63953988
117Aqueductal stenosis (HP:0002410)1.62618444
118Ectopic kidney (HP:0000086)1.62613631
119Broad phalanges of the hand (HP:0009768)1.62247157
120Aplasia involving forearm bones (HP:0009822)1.61510220
121Absent forearm bone (HP:0003953)1.61510220
122Abnormal respiratory motile cilium physiology (HP:0012261)1.61101629
123Arnold-Chiari malformation (HP:0002308)1.60859522
124Bifid scrotum (HP:0000048)1.60839725
125Vertebral arch anomaly (HP:0008438)1.60559151
126Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.60117420
127Labial hypoplasia (HP:0000066)1.59080220
128Abnormality of the pubic bones (HP:0003172)1.58085719
129Preaxial hand polydactyly (HP:0001177)1.57541030
130Increased nuchal translucency (HP:0010880)1.56843004
131Hypoplastic female external genitalia (HP:0012815)1.56683942
132Short middle phalanx of finger (HP:0005819)1.56303567
133Abnormality of the ischium (HP:0003174)1.56007994
134Broad long bones (HP:0005622)1.55731590
135Missing ribs (HP:0000921)1.55579338
136Oligodactyly (HP:0012165)1.55456114
137Abnormality of the diencephalon (HP:0010662)1.55429603
138Tracheomalacia (HP:0002779)1.55146687
139Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.54076716
140Broad phalanx (HP:0006009)1.53925987

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHB23.25013295
2LATS23.06860758
3DDR22.56974748
4PNCK2.54284289
5CASK2.49265142
6FGFR22.33707246
7MAP3K102.28685320
8EPHA42.27563460
9LATS12.27516631
10CDC72.19613653
11TSSK62.16917596
12STK392.12262531
13NTRK22.11461092
14MKNK12.01324072
15BCR2.00876177
16MARK11.98377536
17WEE11.97400797
18LMTK21.85412651
19CAMK1G1.72860262
20TAF11.60081600
21ICK1.60001831
22MKNK21.52973498
23OXSR11.49607641
24SIK11.42364434
25NTRK31.41325528
26CDK191.30576742
27PLK41.29547857
28DYRK21.29347143
29KSR11.26846168
30PDGFRA1.26402080
31NLK1.25978830
32PAK31.25865710
33MAPK131.22760235
34TYRO31.20033664
35FER1.20007607
36WNK41.19117752
37ROCK21.15834779
38PHKG21.14187668
39PHKG11.14187668
40UHMK11.13598358
41DYRK31.11939241
42PAK61.11482826
43PLK21.10047913
44FGFR11.08922901
45ZAK1.08033615
46CAMK1D1.07968772
47NEK21.04068991
48VRK11.03058366
49MINK11.02930857
50VRK21.02727721
51ERBB21.01235887
52CSNK1G11.00319191
53BMPR1B0.99725060
54NTRK10.98248992
55ERBB30.97373271
56PASK0.95867572
57CSNK1A1L0.95354855
58FGR0.94138640
59CSNK1G30.92610054
60PKN10.91655879
61BRSK20.90642534
62DYRK1A0.89893101
63MET0.88727929
64CSNK1G20.87243794
65PAK20.86905401
66PLK10.83559944
67ROCK10.83441678
68WNK10.82777719
69NEK10.81627626
70DMPK0.81239550
71TIE10.80954034
72CDK140.79005232
73BUB10.78991350
74WNK30.78755362
75MAP3K40.78333063
76PRKD30.77820859
77CDK30.77303776
78CHEK20.74012342
79CDK120.73533993
80TTK0.73288878
81CDK150.70779641
82CDK180.70681971
83CAMK2A0.70666296
84MAP2K70.69948309
85BRD40.69524345
86ADRBK10.68583682
87NUAK10.68367357
88TGFBR10.67192786
89CDK50.66947683
90PTK20.65960030
91CAMK2B0.65606727
92MAPK150.65319977
93CDK11A0.65087808
94PRKCE0.64731740
95STK38L0.64715378
96CSNK1E0.63836253
97NEK60.63791232
98ATM0.61763749
99PLK30.59507332
100ATR0.59297995
101BMX0.58769812
102SGK20.58583484
103MAPKAPK50.58025362
104MTOR0.57213575
105SGK2230.56094359
106SGK4940.56094359
107SRPK10.54644786
108PDGFRB0.54544311
109TRIM280.54441831
110TNIK0.53866486
111EPHA30.53148229
112GRK50.50413690
113EEF2K0.49518086
114ERBB40.49354957
115STK30.48762908
116PRKDC0.48718576
117CDC42BPA0.47137459
118PRKCG0.47064374
119YES10.46995059
120MARK20.46904231
121AKT30.46631659
122PBK0.46052069
123CHEK10.44427938
124CSNK1D0.44120440
125STK110.44074090
126CDK10.43532141
127PRKCZ0.43037753
128STK240.42817422
129MAP3K90.42756477
130MELK0.42304530
131AURKB0.41389534
132MAPK100.40716188
133BRSK10.40046232
134CDK20.39909932
135EIF2AK20.36826919
136NME10.34603106
137GSK3B0.33884215

Predicted pathways (KEGG)

RankGene SetZ-score
1Basal cell carcinoma_Homo sapiens_hsa052173.85842865
2Hedgehog signaling pathway_Homo sapiens_hsa043403.27887569
3Hippo signaling pathway_Homo sapiens_hsa043902.61293343
4Axon guidance_Homo sapiens_hsa043602.57363092
5Wnt signaling pathway_Homo sapiens_hsa043102.14182023
6Nicotine addiction_Homo sapiens_hsa050332.05581303
7Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.99787838
8Melanogenesis_Homo sapiens_hsa049161.98883178
9TGF-beta signaling pathway_Homo sapiens_hsa043501.83795153
10Non-homologous end-joining_Homo sapiens_hsa034501.72176065
11Mismatch repair_Homo sapiens_hsa034301.69696236
12Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.59448540
13Spliceosome_Homo sapiens_hsa030401.58871639
14ECM-receptor interaction_Homo sapiens_hsa045121.56751553
15Tight junction_Homo sapiens_hsa045301.52332593
16Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.50309216
17Glutamatergic synapse_Homo sapiens_hsa047241.47628755
18Ribosome_Homo sapiens_hsa030101.42624555
19Adherens junction_Homo sapiens_hsa045201.41611885
20Fatty acid biosynthesis_Homo sapiens_hsa000611.40395586
21Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.39591563
22Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.38652763
23Long-term depression_Homo sapiens_hsa047301.38411940
24DNA replication_Homo sapiens_hsa030301.36268650
25GABAergic synapse_Homo sapiens_hsa047271.35661565
26RNA transport_Homo sapiens_hsa030131.33199784
27Gastric acid secretion_Homo sapiens_hsa049711.31664470
28Protein digestion and absorption_Homo sapiens_hsa049741.30769828
29Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.27641675
30Serotonergic synapse_Homo sapiens_hsa047261.25950113
31Gap junction_Homo sapiens_hsa045401.24209799
32Melanoma_Homo sapiens_hsa052181.24203448
33Renin secretion_Homo sapiens_hsa049241.24147479
34Dorso-ventral axis formation_Homo sapiens_hsa043201.23207439
35Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.22667928
36Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.21237747
37Proteoglycans in cancer_Homo sapiens_hsa052051.19425416
38Salivary secretion_Homo sapiens_hsa049701.18802048
39Cocaine addiction_Homo sapiens_hsa050301.17075949
40Taste transduction_Homo sapiens_hsa047421.16192704
41MicroRNAs in cancer_Homo sapiens_hsa052061.11325242
42Circadian entrainment_Homo sapiens_hsa047131.10574383
43Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.10292292
44Fanconi anemia pathway_Homo sapiens_hsa034601.09579448
45Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.09106914
46Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.08757950
47Steroid biosynthesis_Homo sapiens_hsa001001.08117654
48Pathways in cancer_Homo sapiens_hsa052001.07322966
49Thyroid cancer_Homo sapiens_hsa052161.06402834
50Lysine degradation_Homo sapiens_hsa003101.05597845
51Notch signaling pathway_Homo sapiens_hsa043301.04849706
52Rap1 signaling pathway_Homo sapiens_hsa040151.04733786
53Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.03319567
54Dopaminergic synapse_Homo sapiens_hsa047281.01604569
55Ether lipid metabolism_Homo sapiens_hsa005651.00853373
56Amphetamine addiction_Homo sapiens_hsa050310.99271195
57Long-term potentiation_Homo sapiens_hsa047200.98400446
58Morphine addiction_Homo sapiens_hsa050320.97511368
59Dilated cardiomyopathy_Homo sapiens_hsa054140.96595345
60Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.96106797
61Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.94598741
62ErbB signaling pathway_Homo sapiens_hsa040120.94335907
63Focal adhesion_Homo sapiens_hsa045100.92280677
64Pancreatic secretion_Homo sapiens_hsa049720.91650051
65Propanoate metabolism_Homo sapiens_hsa006400.91304016
66Homologous recombination_Homo sapiens_hsa034400.90516513
67Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.89416791
68Colorectal cancer_Homo sapiens_hsa052100.88527188
69Prostate cancer_Homo sapiens_hsa052150.88240460
70Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.86476488
71Calcium signaling pathway_Homo sapiens_hsa040200.86125555
72Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.85636952
73Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.85592895
74cAMP signaling pathway_Homo sapiens_hsa040240.84296371
75Base excision repair_Homo sapiens_hsa034100.84284143
76Ras signaling pathway_Homo sapiens_hsa040140.84206831
77Oocyte meiosis_Homo sapiens_hsa041140.82966446
78Endometrial cancer_Homo sapiens_hsa052130.81481327
79Basal transcription factors_Homo sapiens_hsa030220.81162089
80Renal cell carcinoma_Homo sapiens_hsa052110.80984219
81Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.80776319
82Cysteine and methionine metabolism_Homo sapiens_hsa002700.80553779
83Nucleotide excision repair_Homo sapiens_hsa034200.80193354
84Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.79876438
85Estrogen signaling pathway_Homo sapiens_hsa049150.78947986
86Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.78268491
87GnRH signaling pathway_Homo sapiens_hsa049120.77357769
88Cholinergic synapse_Homo sapiens_hsa047250.76854264
89Choline metabolism in cancer_Homo sapiens_hsa052310.76764867
90PI3K-Akt signaling pathway_Homo sapiens_hsa041510.76741064
91Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.76505361
92Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.76171146
93Cardiac muscle contraction_Homo sapiens_hsa042600.74957578
94Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.72965825
95Central carbon metabolism in cancer_Homo sapiens_hsa052300.72562068
96Huntingtons disease_Homo sapiens_hsa050160.71945650
97cGMP-PKG signaling pathway_Homo sapiens_hsa040220.71642766
98Ovarian steroidogenesis_Homo sapiens_hsa049130.71367660
99Mineral absorption_Homo sapiens_hsa049780.70475777
100Glioma_Homo sapiens_hsa052140.69524477
101Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.69336235
102mRNA surveillance pathway_Homo sapiens_hsa030150.69041259
103Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.68671929
104Insulin secretion_Homo sapiens_hsa049110.67987155
105RNA degradation_Homo sapiens_hsa030180.66831563
106Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.66756073
107Regulation of actin cytoskeleton_Homo sapiens_hsa048100.66633231
108Oxytocin signaling pathway_Homo sapiens_hsa049210.66588141
109Vascular smooth muscle contraction_Homo sapiens_hsa042700.66156869
110Phospholipase D signaling pathway_Homo sapiens_hsa040720.65403391
111Bladder cancer_Homo sapiens_hsa052190.65328522
112Thyroid hormone synthesis_Homo sapiens_hsa049180.64086184
113Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.63186435
114Protein export_Homo sapiens_hsa030600.63029583
115RNA polymerase_Homo sapiens_hsa030200.60966826
116Phototransduction_Homo sapiens_hsa047440.58356450
117Selenocompound metabolism_Homo sapiens_hsa004500.57958715
118Pyruvate metabolism_Homo sapiens_hsa006200.57686654
119Aldosterone synthesis and secretion_Homo sapiens_hsa049250.55883122
120MAPK signaling pathway_Homo sapiens_hsa040100.54924397
121Thyroid hormone signaling pathway_Homo sapiens_hsa049190.52414704
122Sphingolipid signaling pathway_Homo sapiens_hsa040710.51636910
123Biosynthesis of amino acids_Homo sapiens_hsa012300.46294773
124Sphingolipid metabolism_Homo sapiens_hsa006000.45547609
125Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.45414546
126One carbon pool by folate_Homo sapiens_hsa006700.44516849
127Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.44318407
128Cell cycle_Homo sapiens_hsa041100.43723436
129Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.43650968
130Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.43043713
131Alcoholism_Homo sapiens_hsa050340.42964955
132Small cell lung cancer_Homo sapiens_hsa052220.42147840
133Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.40851468
134Folate biosynthesis_Homo sapiens_hsa007900.38044476
135Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.35277881

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