CACNB1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1actin-myosin filament sliding (GO:0033275)7.04458478
2muscle filament sliding (GO:0030049)7.04458478
3synaptic vesicle maturation (GO:0016188)6.53072702
4skeletal muscle contraction (GO:0003009)6.08187945
5regulation of short-term neuronal synaptic plasticity (GO:0048172)5.75092148
6actin-mediated cell contraction (GO:0070252)5.67674025
7regulation of skeletal muscle contraction (GO:0014819)5.52572833
8locomotory exploration behavior (GO:0035641)5.45204360
9positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.38526712
10positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.14205030
11vocalization behavior (GO:0071625)5.09746001
12regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.07999164
13synaptic vesicle exocytosis (GO:0016079)4.85569357
14glutamate secretion (GO:0014047)4.84394563
15striated muscle contraction (GO:0006941)4.81926970
16positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)4.78436039
17regulation of glutamate receptor signaling pathway (GO:1900449)4.72963334
18synaptic vesicle docking involved in exocytosis (GO:0016081)4.69258651
19regulation of synapse structural plasticity (GO:0051823)4.64221524
20regulation of synaptic vesicle exocytosis (GO:2000300)4.54506042
21skeletal muscle fiber development (GO:0048741)4.51104996
22protein localization to synapse (GO:0035418)4.50585691
23neuronal action potential propagation (GO:0019227)4.45752113
24creatine metabolic process (GO:0006600)4.44914171
25proline transport (GO:0015824)4.42937971
26regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)4.36193965
27regulation of relaxation of muscle (GO:1901077)4.34116780
28actin filament-based movement (GO:0030048)4.31309251
29regulation of neuronal synaptic plasticity (GO:0048168)4.30199469
30regulation of long-term neuronal synaptic plasticity (GO:0048169)4.28838148
31regulation of cell communication by electrical coupling (GO:0010649)4.27783047
32exploration behavior (GO:0035640)4.20759439
33ionotropic glutamate receptor signaling pathway (GO:0035235)4.18854644
34myofibril assembly (GO:0030239)4.17764185
35response to inactivity (GO:0014854)4.16406476
36layer formation in cerebral cortex (GO:0021819)4.15772017
37regulation of synaptic vesicle transport (GO:1902803)4.14670562
38response to stimulus involved in regulation of muscle adaptation (GO:0014874)4.12164971
39dendritic spine morphogenesis (GO:0060997)4.08663934
40neurotransmitter secretion (GO:0007269)4.06382988
41myotube cell development (GO:0014904)3.96091253
42regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)3.95067504
43membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.92125871
44synaptic transmission, glutamatergic (GO:0035249)3.89725129
45cardiac muscle contraction (GO:0060048)3.85510844
46response to muscle activity (GO:0014850)3.80837275
47regulation of dendritic spine morphogenesis (GO:0061001)3.80296282
48neuron cell-cell adhesion (GO:0007158)3.77278113
49neurotransmitter-gated ion channel clustering (GO:0072578)3.75002303
50regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.69347205
51positive regulation of synapse maturation (GO:0090129)3.67217182
52muscle contraction (GO:0006936)3.63744168
53sarcomere organization (GO:0045214)3.63478501
54neuron-neuron synaptic transmission (GO:0007270)3.61188159
55glutamate receptor signaling pathway (GO:0007215)3.59478031
56long-term memory (GO:0007616)3.58444872
57auditory behavior (GO:0031223)3.58409977
58neuromuscular process controlling balance (GO:0050885)3.54150636
59regulation of excitatory postsynaptic membrane potential (GO:0060079)3.54109667
60regulation of synapse maturation (GO:0090128)3.53427832
61activation of protein kinase A activity (GO:0034199)3.52718002
62positive regulation of synaptic transmission, GABAergic (GO:0032230)3.47418711
63positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.46586291
64positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.45800053
65regulation of calcium ion transmembrane transporter activity (GO:1901019)3.44883345
66regulation of calcium ion transmembrane transport (GO:1903169)3.44883345
67positive regulation of membrane potential (GO:0045838)3.43476602
68cerebellar granule cell differentiation (GO:0021707)3.42213365
69regulation of synaptic plasticity (GO:0048167)3.38443435
70prepulse inhibition (GO:0060134)3.38175907
71regulation of postsynaptic membrane potential (GO:0060078)3.34832918
72cardiac myofibril assembly (GO:0055003)3.32800003
73behavioral fear response (GO:0001662)3.30798265
74behavioral defense response (GO:0002209)3.30798265
75cellular potassium ion homeostasis (GO:0030007)3.30395790
76membrane depolarization during action potential (GO:0086010)3.29096232
77muscle fiber development (GO:0048747)3.27560672
78neurotransmitter transport (GO:0006836)3.27297365
79establishment of mitochondrion localization (GO:0051654)3.26928705
80G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.25226985
81muscle system process (GO:0003012)3.24899974
82response to auditory stimulus (GO:0010996)3.23358915
83cell migration in hindbrain (GO:0021535)3.22151756
84negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.21625087
85gamma-aminobutyric acid transport (GO:0015812)3.20756940
86regulation of voltage-gated calcium channel activity (GO:1901385)3.20701602
87regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.20022067
88regulation of membrane repolarization (GO:0060306)3.16704757
89regulation of synaptic transmission, glutamatergic (GO:0051966)3.13268821
90regulation of dendritic spine development (GO:0060998)3.11713909
91neuron recognition (GO:0008038)3.11092714
92regulation of actin filament-based movement (GO:1903115)3.10656052
93neuromuscular synaptic transmission (GO:0007274)3.10234755
94transmission of nerve impulse (GO:0019226)3.08187096
95sodium ion export (GO:0071436)3.07357799
96neuronal ion channel clustering (GO:0045161)3.07057128
97regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)3.07018873
98regulation of neurotransmitter levels (GO:0001505)3.04038191
99mitochondrion transport along microtubule (GO:0047497)3.03227340
100establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.03227340
101membrane depolarization (GO:0051899)3.02566270
102positive regulation of neurotransmitter transport (GO:0051590)3.02404541
103regulation of vesicle fusion (GO:0031338)3.02344639
104negative regulation of calcium ion transmembrane transporter activity (GO:1901020)3.01984706
105negative regulation of calcium ion transmembrane transport (GO:1903170)3.01984706
106fear response (GO:0042596)3.01761436
107regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO3.00920120
108positive regulation of neurotransmitter secretion (GO:0001956)3.00849931
109striatum development (GO:0021756)2.99703298
110regulation of neurotransmitter secretion (GO:0046928)2.99521238
111dendritic spine organization (GO:0097061)2.99376953
112postsynaptic membrane organization (GO:0001941)2.98580054
113potassium ion import (GO:0010107)2.97955244
114cardiac muscle hypertrophy (GO:0003300)2.97801182
115regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)2.95669610
116positive regulation of calcium ion transmembrane transporter activity (GO:1901021)2.94830806
117synaptic vesicle endocytosis (GO:0048488)2.94632227
118positive regulation of dendritic spine development (GO:0060999)2.94227404
119dendrite morphogenesis (GO:0048813)2.94063954
120axonal fasciculation (GO:0007413)2.93816756
121neuromuscular process (GO:0050905)2.91021264
122skeletal muscle tissue development (GO:0007519)2.89576449
123striated muscle adaptation (GO:0014888)2.89195468
124positive regulation of myotube differentiation (GO:0010831)2.87794761
125long-term synaptic potentiation (GO:0060291)2.87575998
126actomyosin structure organization (GO:0031032)2.86724622
127negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.86057229
128cerebellar Purkinje cell differentiation (GO:0021702)2.84643147
129learning (GO:0007612)2.83229859
130striated muscle hypertrophy (GO:0014897)2.82598315
131skeletal muscle adaptation (GO:0043501)2.81607599
132regulation of skeletal muscle cell differentiation (GO:2001014)2.81588726
133neuromuscular process controlling posture (GO:0050884)2.80685749
134regulation of neurotransmitter transport (GO:0051588)2.80422983
135cell communication by electrical coupling (GO:0010644)2.80356004
136plasma membrane repair (GO:0001778)2.80210757
137cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.79772391
138dopamine receptor signaling pathway (GO:0007212)2.78650246
139negative regulation of potassium ion transmembrane transport (GO:1901380)2.78419354
140sarcoplasmic reticulum calcium ion transport (GO:0070296)2.78401666
141positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.77867905
142regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.77391726
143intraspecies interaction between organisms (GO:0051703)2.77144337
144social behavior (GO:0035176)2.77144337
145vesicle transport along microtubule (GO:0047496)2.77099790
146positive regulation of dendritic spine morphogenesis (GO:0061003)2.75918857
147chemosensory behavior (GO:0007635)2.75129894
148calcium-mediated signaling using intracellular calcium source (GO:0035584)2.75103194
149membrane hyperpolarization (GO:0060081)2.75049225

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.71398863
2* RARB_27405468_Chip-Seq_BRAIN_Mouse3.20400742
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.93865628
4JARID2_20064375_ChIP-Seq_MESCs_Mouse2.83716063
5REST_21632747_ChIP-Seq_MESCs_Mouse2.79742126
6RNF2_18974828_ChIP-Seq_MESCs_Mouse2.75941536
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.75941536
8SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.71952420
9EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.67768357
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.57213317
11MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.43649350
12EZH2_27304074_Chip-Seq_ESCs_Mouse2.42754233
13SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.40617034
14REST_18959480_ChIP-ChIP_MESCs_Mouse2.40458911
15MTF2_20144788_ChIP-Seq_MESCs_Mouse2.38584608
16DROSHA_22980978_ChIP-Seq_HELA_Human2.37905789
17IKZF1_21737484_ChIP-ChIP_HCT116_Human2.36060172
18SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.33163199
19SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.31008128
20SUZ12_27294783_Chip-Seq_ESCs_Mouse2.27046119
21EZH2_27294783_Chip-Seq_ESCs_Mouse2.25459556
22RNF2_27304074_Chip-Seq_ESCs_Mouse2.24648015
23TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.22776467
24GBX2_23144817_ChIP-Seq_PC3_Human2.20758994
25SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.11328881
26ERG_21242973_ChIP-ChIP_JURKAT_Human1.98648058
27* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.95621079
28ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.94445838
29CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.85525251
30EED_16625203_ChIP-ChIP_MESCs_Mouse1.79082426
31SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.78593728
32RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.74664077
33NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.70858965
34KDM2B_26808549_Chip-Seq_K562_Human1.66574142
35DNAJC2_21179169_ChIP-ChIP_NT2_Human1.61104132
36GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.59920223
37* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.56867563
38ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.51150637
39* ZFP281_27345836_Chip-Seq_ESCs_Mouse1.50708023
40PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.49912105
41RING1B_27294783_Chip-Seq_ESCs_Mouse1.49481755
42BP1_19119308_ChIP-ChIP_Hs578T_Human1.48424591
43* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.47788101
44* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.47137837
45RING1B_27294783_Chip-Seq_NPCs_Mouse1.42467423
46EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.35981947
47ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.34076719
48TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.32660676
49OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.32208427
50AR_21572438_ChIP-Seq_LNCaP_Human1.29930431
51KDM2B_26808549_Chip-Seq_SUP-B15_Human1.29450818
52WT1_25993318_ChIP-Seq_PODOCYTE_Human1.26601382
53CTCF_27219007_Chip-Seq_Bcells_Human1.21733045
54ESR2_21235772_ChIP-Seq_MCF-7_Human1.21548493
55RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.20807189
56TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.19259591
57TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.18079978
58AR_19668381_ChIP-Seq_PC3_Human1.17640578
59STAT6_21828071_ChIP-Seq_BEAS2B_Human1.16941086
60CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.16644966
61SOX2_21211035_ChIP-Seq_LN229_Gbm1.16175672
62P53_22127205_ChIP-Seq_FIBROBLAST_Human1.15031893
63RBPJ_22232070_ChIP-Seq_NCS_Mouse1.14505616
64CTBP1_25329375_ChIP-Seq_LNCAP_Human1.13913850
65GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.10741559
66TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.10120825
67RNF2_27304074_Chip-Seq_NSC_Mouse1.08479646
68PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.07886233
69CTBP2_25329375_ChIP-Seq_LNCAP_Human1.07286753
70TP53_20018659_ChIP-ChIP_R1E_Mouse1.07221221
71* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.07134429
72* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.07047029
73SMC4_20622854_ChIP-Seq_HELA_Human1.06982871
74SMAD3_21741376_ChIP-Seq_HESCs_Human1.06076933
75KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.06018462
76KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.06018462
77KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.06018462
78NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.05943272
79SMAD4_21799915_ChIP-Seq_A2780_Human1.05188632
80THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.05178843
81TET1_21490601_ChIP-Seq_MESCs_Mouse1.03822423
82TRIM28_21343339_ChIP-Seq_HEK293_Human1.02578719
83MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.00741121
84TBX20_22328084_ChIP-Seq_HEART_Mouse0.99574511
85TBX20_22080862_ChIP-Seq_HEART_Mouse0.99574511
86LXR_22292898_ChIP-Seq_THP-1_Human0.98872208
87SRY_22984422_ChIP-ChIP_TESTIS_Rat0.97499710
88MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.96016159
89CBX2_27304074_Chip-Seq_ESCs_Mouse0.95269128
90CDX2_19796622_ChIP-Seq_MESCs_Mouse0.94725641
91SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.94162020
92* RARG_19884340_ChIP-ChIP_MEFs_Mouse0.93551172
93SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.92748892
94MYC_27129775_Chip-Seq_CORNEA_Mouse0.92515168
95OCT4_19829295_ChIP-Seq_ESCs_Human0.91799629
96YAP1_20516196_ChIP-Seq_MESCs_Mouse0.91437273
97RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.90390375
98TP53_23651856_ChIP-Seq_MEFs_Mouse0.90243134
99AHR_22903824_ChIP-Seq_MCF-7_Human0.89572390
100DPY_21335234_ChIP-Seq_ESCs_Mouse0.89167511
101EP300_21415370_ChIP-Seq_HL-1_Mouse0.88841883
102BMI1_23680149_ChIP-Seq_NPCS_Mouse0.88661050
103DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.88554238
104CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.88523221
105NFIB_24661679_ChIP-Seq_LUNG_Mouse0.88286165
106STAT3_23295773_ChIP-Seq_U87_Human0.86996476
107ARNT_22903824_ChIP-Seq_MCF-7_Human0.86909666
108SMAD4_21741376_ChIP-Seq_HESCs_Human0.86601494
109P68_20966046_ChIP-Seq_HELA_Human0.86334607
110KDM2B_26808549_Chip-Seq_DND41_Human0.85683561
111KLF4_19829295_ChIP-Seq_ESCs_Human0.84863337
112ZNF274_21170338_ChIP-Seq_K562_Hela0.84379805
113* SA1_27219007_Chip-Seq_Bcells_Human0.84266930
114CTCF_27219007_Chip-Seq_ERYTHROID_Human0.82063007
115* TET1_21451524_ChIP-Seq_MESCs_Mouse0.81878325
116GATA1_26923725_Chip-Seq_HPCs_Mouse0.81425294
117ELK4_26923725_Chip-Seq_MESODERM_Mouse0.81108914
118NR3C1_23031785_ChIP-Seq_PC12_Mouse0.80017467
119NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.79033308
120SMAD3_21741376_ChIP-Seq_ESCs_Human0.78533587
121ESR1_20079471_ChIP-ChIP_T-47D_Human0.78248540
122RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.78222616
123KDM2B_26808549_Chip-Seq_JURKAT_Human0.78202819
124PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.77856416
125PRDM14_21183938_ChIP-Seq_MESCs_Mouse0.77751732
126CREB1_26743006_Chip-Seq_LNCaP_Human0.77032317

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.51254624
2MP0004270_analgesia4.10058682
3MP0003880_abnormal_central_pattern4.05047579
4MP0003635_abnormal_synaptic_transmissio3.87308795
5MP0002822_catalepsy3.48465183
6MP0002063_abnormal_learning/memory/cond3.15994977
7MP0009745_abnormal_behavioral_response3.03651437
8MP0002064_seizures2.77676212
9MP0004858_abnormal_nervous_system2.70788617
10MP0009046_muscle_twitch2.66964649
11MP0002572_abnormal_emotion/affect_behav2.59058564
12MP0004145_abnormal_muscle_electrophysio2.48936337
13MP0002734_abnormal_mechanical_nocicepti2.44300250
14MP0005423_abnormal_somatic_nervous2.44015378
15MP0001486_abnormal_startle_reflex2.41840415
16MP0001968_abnormal_touch/_nociception2.39008839
17MP0002272_abnormal_nervous_system2.19605148
18MP0000751_myopathy2.18318793
19MP0001501_abnormal_sleep_pattern1.90541331
20MP0002909_abnormal_adrenal_gland1.89732329
21MP0002733_abnormal_thermal_nociception1.89394580
22MP0001440_abnormal_grooming_behavior1.87268382
23MP0000749_muscle_degeneration1.80182674
24MP0004084_abnormal_cardiac_muscle1.77818494
25MP0001970_abnormal_pain_threshold1.75503436
26MP0004811_abnormal_neuron_physiology1.74519882
27MP0008961_abnormal_basal_metabolism1.71694802
28MP0002184_abnormal_innervation1.69655094
29MP0003122_maternal_imprinting1.66802587
30MP0008569_lethality_at_weaning1.65842174
31MP0000955_abnormal_spinal_cord1.61507716
32MP0002736_abnormal_nociception_after1.61467116
33MP0009780_abnormal_chondrocyte_physiolo1.61068965
34MP0002067_abnormal_sensory_capabilities1.57359930
35MP0000778_abnormal_nervous_system1.56729500
36MP0005499_abnormal_olfactory_system1.56657105
37MP0005394_taste/olfaction_phenotype1.56657105
38MP0000733_abnormal_muscle_development1.56008072
39MP0002735_abnormal_chemical_nociception1.55519584
40MP0005451_abnormal_body_composition1.55518860
41MP0003787_abnormal_imprinting1.50103644
42MP0002557_abnormal_social/conspecific_i1.49755477
43MP0003646_muscle_fatigue1.46151236
44MP0004924_abnormal_behavior1.42081181
45MP0005386_behavior/neurological_phenoty1.42081181
46MP0003329_amyloid_beta_deposits1.37328219
47MP0005330_cardiomyopathy1.33951482
48MP0000747_muscle_weakness1.32752069
49MP0002882_abnormal_neuron_morphology1.31954698
50MP0002972_abnormal_cardiac_muscle1.30327140
51* MP0002066_abnormal_motor_capabilities/c1.28865720
52MP0001529_abnormal_vocalization1.26474575
53MP0003879_abnormal_hair_cell1.23424826
54MP0004510_myositis1.19562389
55MP0004885_abnormal_endolymph1.19033855
56MP0002332_abnormal_exercise_endurance1.16089331
57* MP0000759_abnormal_skeletal_muscle1.15987391
58MP0002269_muscular_atrophy1.15781744
59MP0003283_abnormal_digestive_organ1.13666857
60MP0001984_abnormal_olfaction1.13248219
61MP0006276_abnormal_autonomic_nervous1.12830120
62MP0004142_abnormal_muscle_tone1.12410032
63MP0003137_abnormal_impulse_conducting1.10621340
64MP0005646_abnormal_pituitary_gland1.10413002
65MP0003633_abnormal_nervous_system1.09371720
66MP0006292_abnormal_olfactory_placode1.09341276
67MP0002837_dystrophic_cardiac_calcinosis1.08774031
68MP0004233_abnormal_muscle_weight1.08231985
69* MP0002106_abnormal_muscle_physiology1.04373990
70MP0002152_abnormal_brain_morphology1.01306232
71MP0008872_abnormal_physiological_respon1.00036897
72MP0001905_abnormal_dopamine_level0.99039467
73MP0003123_paternal_imprinting0.98707099
74MP0002653_abnormal_ependyma_morphology0.98442610
75MP0004085_abnormal_heartbeat0.97783515
76MP0008874_decreased_physiological_sensi0.93913252
77MP0001299_abnormal_eye_distance/0.92641186
78MP0006036_abnormal_mitochondrial_physio0.91695497
79* MP0005369_muscle_phenotype0.91386988
80* MP0005620_abnormal_muscle_contractility0.90762069
81* MP0004087_abnormal_muscle_fiber0.89562804
82MP0004036_abnormal_muscle_relaxation0.89344578
83MP0010630_abnormal_cardiac_muscle0.89118876
84MP0002069_abnormal_eating/drinking_beha0.87360726
85MP0003075_altered_response_to0.87287277
86MP0006138_congestive_heart_failure0.85340320
87MP0003631_nervous_system_phenotype0.84312416
88MP0006035_abnormal_mitochondrial_morpho0.84123768
89MP0004215_abnormal_myocardial_fiber0.82444374
90MP0001346_abnormal_lacrimal_gland0.81808856
91MP0002638_abnormal_pupillary_reflex0.79151861
92MP0005623_abnormal_meninges_morphology0.78464673
93MP0000013_abnormal_adipose_tissue0.77996859
94MP0000750_abnormal_muscle_regeneration0.76592875
95MP0004043_abnormal_pH_regulation0.76528834
96MP0002254_reproductive_system_inflammat0.76513985
97MP0004130_abnormal_muscle_cell0.76376820
98MP0005645_abnormal_hypothalamus_physiol0.76018583
99MP0002752_abnormal_somatic_nervous0.75202022
100MP0002249_abnormal_larynx_morphology0.73633821
101MP0002229_neurodegeneration0.72892177
102MP0000920_abnormal_myelination0.72419282
103MP0003938_abnormal_ear_development0.71879021
104MP0001544_abnormal_cardiovascular_syste0.71309800
105MP0005385_cardiovascular_system_phenoty0.71309800
106MP0001502_abnormal_circadian_rhythm0.71236343
107MP0003121_genomic_imprinting0.70703959
108MP0001348_abnormal_lacrimal_gland0.70619698
109MP0000631_abnormal_neuroendocrine_gland0.68040351
110MP0003690_abnormal_glial_cell0.67341007
111MP0003861_abnormal_nervous_system0.66105434
112MP0004484_altered_response_of0.64884192
113MP0003634_abnormal_glial_cell0.64813862
114MP0003045_fibrosis0.63558371
115MP0002127_abnormal_cardiovascular_syste0.63366274
116MP0005535_abnormal_body_temperature0.63271158
117MP0001943_abnormal_respiration0.62816262
118MP0005266_abnormal_metabolism0.62259587
119MP0002971_abnormal_brown_adipose0.61893282
120MP0003890_abnormal_embryonic-extraembry0.61509443
121MP0008770_decreased_survivor_rate0.58146557
122MP0002108_abnormal_muscle_morphology0.56489933
123MP0001963_abnormal_hearing_physiology0.55157954
124MP0004134_abnormal_chest_morphology0.54395729

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)5.94099489
2Focal motor seizures (HP:0011153)5.86743695
3Focal seizures (HP:0007359)4.73801663
4Muscle fiber splitting (HP:0003555)4.32960967
5Visual hallucinations (HP:0002367)4.28982225
6Abnormality of the lower motor neuron (HP:0002366)4.28311395
7Calcaneovalgus deformity (HP:0001848)4.02769105
8Exercise-induced myalgia (HP:0003738)3.89852366
9Epileptic encephalopathy (HP:0200134)3.84795759
10Centrally nucleated skeletal muscle fibers (HP:0003687)3.75917209
11Febrile seizures (HP:0002373)3.66423701
12Difficulty running (HP:0009046)3.59104374
13Muscle fiber inclusion bodies (HP:0100299)3.58724536
14Deformed tarsal bones (HP:0008119)3.52603276
15Myoglobinuria (HP:0002913)3.49360245
16Atonic seizures (HP:0010819)3.43734800
17Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)3.40823217
18Subaortic stenosis (HP:0001682)3.40394662
19Abnormality of the left ventricular outflow tract (HP:0011103)3.40394662
20Neck muscle weakness (HP:0000467)3.37045277
21Rhabdomyolysis (HP:0003201)3.32882934
22Generalized tonic-clonic seizures (HP:0002069)3.22373652
23Rimmed vacuoles (HP:0003805)3.21680964
24Nemaline bodies (HP:0003798)3.21305743
25Absent phalangeal crease (HP:0006109)3.18876400
26Dialeptic seizures (HP:0011146)3.18784467
27Absence seizures (HP:0002121)3.17945365
28Ankle clonus (HP:0011448)3.17467830
29Amblyopia (HP:0000646)3.16530472
30Exercise-induced muscle cramps (HP:0003710)3.12712653
31Distal lower limb muscle weakness (HP:0009053)3.06637144
32Fetal akinesia sequence (HP:0001989)3.02654721
33Frequent falls (HP:0002359)3.01843253
34Malignant hyperthermia (HP:0002047)3.01245611
35Hyperventilation (HP:0002883)2.86332638
36Type 1 muscle fiber predominance (HP:0003803)2.85007392
37Impaired vibration sensation in the lower limbs (HP:0002166)2.84783883
38Action tremor (HP:0002345)2.83241173
39Broad-based gait (HP:0002136)2.80553120
40Distal arthrogryposis (HP:0005684)2.79434405
41Progressive cerebellar ataxia (HP:0002073)2.78521405
42Resting tremor (HP:0002322)2.77877760
43Poor eye contact (HP:0000817)2.77654434
44Supranuclear gaze palsy (HP:0000605)2.75985829
45Urinary bladder sphincter dysfunction (HP:0002839)2.71309464
46Depression (HP:0000716)2.70927217
47Bilateral microphthalmos (HP:0007633)2.67030570
48Myopathic facies (HP:0002058)2.66077241
49Muscle hypertrophy of the lower extremities (HP:0008968)2.63481172
50Amyotrophic lateral sclerosis (HP:0007354)2.62797826
51Asymmetric septal hypertrophy (HP:0001670)2.58240705
52Myotonia (HP:0002486)2.58049616
53Abnormal finger flexion creases (HP:0006143)2.57839111
54Impaired social interactions (HP:0000735)2.53626848
55Abnormal social behavior (HP:0012433)2.53626848
56Increased variability in muscle fiber diameter (HP:0003557)2.53125320
57Obstructive sleep apnea (HP:0002870)2.50740909
58Hemiparesis (HP:0001269)2.46414388
59Urinary urgency (HP:0000012)2.46241344
60Scapular winging (HP:0003691)2.46137083
61Gowers sign (HP:0003391)2.46039355
62Hip contracture (HP:0003273)2.45266981
63Round ear (HP:0100830)2.44336502
64Abnormality of skeletal muscle fiber size (HP:0012084)2.43756405
65Dysdiadochokinesis (HP:0002075)2.42620368
66Lower limb amyotrophy (HP:0007210)2.41863578
67Hepatoblastoma (HP:0002884)2.41096093
68Fatigable weakness (HP:0003473)2.38925864
69Abnormality of the neuromuscular junction (HP:0003398)2.38925864
70Abnormality of the calcaneus (HP:0008364)2.38560122
71Postural instability (HP:0002172)2.38518350
72Calf muscle hypertrophy (HP:0008981)2.37701180
73Weak cry (HP:0001612)2.36868936
74Neoplasm of the heart (HP:0100544)2.35493435
75Abnormality of the foot musculature (HP:0001436)2.34973546
76Achilles tendon contracture (HP:0001771)2.34458410
77Areflexia of lower limbs (HP:0002522)2.34394896
78Decreased number of large peripheral myelinated nerve fibers (HP:0003387)2.34299405
79EMG: myopathic abnormalities (HP:0003458)2.34276810
80Generalized muscle weakness (HP:0003324)2.33439471
81EMG: neuropathic changes (HP:0003445)2.29868592
82Foot dorsiflexor weakness (HP:0009027)2.29249555
83Bulbar palsy (HP:0001283)2.27907152
84Annular pancreas (HP:0001734)2.25222064
85Akinesia (HP:0002304)2.25171148
86Anxiety (HP:0000739)2.22704027
87Mutism (HP:0002300)2.20919337
88Dysmetria (HP:0001310)2.19702902
89Limb-girdle muscle atrophy (HP:0003797)2.16988662
90Generalized hypotonia (HP:0001290)2.15815539
91Drooling (HP:0002307)2.15651014
92Excessive salivation (HP:0003781)2.15651014
93Abnormality of the corticospinal tract (HP:0002492)2.15477955
94Rapidly progressive (HP:0003678)2.13502875
95Lower limb muscle weakness (HP:0007340)2.13195822
96Slender build (HP:0001533)2.12705268
97Spastic gait (HP:0002064)2.12049254
98Gaze-evoked nystagmus (HP:0000640)2.08375595
99Shoulder girdle muscle weakness (HP:0003547)2.07480771
100Papilledema (HP:0001085)2.07166086
101Mildly elevated creatine phosphokinase (HP:0008180)2.06885780
102Impaired vibratory sensation (HP:0002495)2.05842922
103Torticollis (HP:0000473)2.03417247
104Testicular atrophy (HP:0000029)2.02695741
105Bradykinesia (HP:0002067)2.02524481
106Difficulty climbing stairs (HP:0003551)2.02306092
107Nonprogressive disorder (HP:0003680)2.01646267
108Abnormality of the Achilles tendon (HP:0005109)2.01296080
109Hyporeflexia of lower limbs (HP:0002600)2.01039912
110Genetic anticipation (HP:0003743)1.99871016
111Abnormality of the calf musculature (HP:0001430)1.99396356
112Heart block (HP:0012722)1.98709090
113Ankyloglossia (HP:0010296)1.98544868
114Stereotypic behavior (HP:0000733)1.98488537
115Diplopia (HP:0000651)1.98291125
116Abnormality of binocular vision (HP:0011514)1.98291125
117Waddling gait (HP:0002515)1.97870652
118Popliteal pterygium (HP:0009756)1.96700329
119Ventricular fibrillation (HP:0001663)1.96624990
120Abnormal eating behavior (HP:0100738)1.95154126
121Hyperkalemia (HP:0002153)1.94969247
122Spinal rigidity (HP:0003306)1.94673267
123Truncal ataxia (HP:0002078)1.94432191
124Status epilepticus (HP:0002133)1.93508529
125Metatarsus adductus (HP:0001840)1.92911549
126Horizontal nystagmus (HP:0000666)1.91567812
127Ulnar deviation of the wrist (HP:0003049)1.91007637
128Dysmetric saccades (HP:0000641)1.88364168
129Abnormal atrioventricular conduction (HP:0005150)1.87161336
130Impaired smooth pursuit (HP:0007772)1.85753502
131Abnormal EKG (HP:0003115)1.85500854
132Distal lower limb amyotrophy (HP:0008944)1.84229293
133Focal dystonia (HP:0004373)1.84168846
134Inability to walk (HP:0002540)1.83727690
135Increased connective tissue (HP:0009025)1.83312114
136Pointed chin (HP:0000307)1.83236247
137Sudden death (HP:0001699)1.83093545
138Bundle branch block (HP:0011710)1.82715488
139Abnormality of the shoulder girdle musculature (HP:0001435)1.81516341
140Upper limb amyotrophy (HP:0009129)1.81120555
141Distal upper limb amyotrophy (HP:0007149)1.81120555
142Proximal amyotrophy (HP:0007126)1.80801062
143Abnormality of ocular smooth pursuit (HP:0000617)1.78137489
144Muscle stiffness (HP:0003552)1.77833091
145Type 2 muscle fiber atrophy (HP:0003554)1.77091754
146Limited hip movement (HP:0008800)1.75819314
147Limb dystonia (HP:0002451)1.72629961
148Respiratory insufficiency due to muscle weakness (HP:0002747)1.69141279
149Muscle fiber atrophy (HP:0100295)1.65424168

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA44.67420038
2MAP3K93.94964772
3NTRK33.84456289
4GRK52.85006067
5MARK12.82232101
6PRKD32.40675388
7DAPK22.34726411
8MAP3K42.28301420
9PAK62.25077593
10MINK12.21640834
11TYRO32.21314480
12MAP2K42.13155884
13NTRK12.10543707
14KSR22.05227052
15NTRK21.98559580
16PHKG11.89499810
17PHKG21.89499810
18CDK121.58565502
19CAMKK11.55737815
20MAP2K71.54255275
21RIPK41.51250514
22KSR11.47426601
23PIK3CG1.45781341
24CDK51.42542909
25OBSCN1.41823386
26TAOK11.39044607
27STK381.38586207
28SIK21.36501627
29DAPK11.31804376
30MARK21.29762599
31LATS21.24512838
32GRK61.18730679
33MAP3K71.09584694
34PRPF4B1.08709992
35NME11.07621742
36PRKCG1.06941079
37LIMK11.05955124
38CAMK2G1.03467161
39MOS1.02753704
40PINK11.02079049
41NEK10.96844398
42ARAF0.95503081
43CDK150.94064479
44UHMK10.93327323
45CDK180.93189136
46MAPK130.92191974
47CDK190.91151368
48ALK0.90524728
49MAP3K120.90335839
50CAMK40.90184856
51FES0.89292989
52WNK10.88385625
53CDK140.86080130
54PKN10.85390405
55CDK11A0.83591368
56MAP3K130.83576735
57CAMK10.82886697
58MAPK120.82312238
59MAPK70.81115351
60PLK20.80851858
61STK110.80460598
62ADRBK20.80278363
63TNIK0.78941976
64MAP3K20.76873696
65SGK20.73985034
66DYRK1B0.72537643
67PRKCH0.71062637
68CCNB10.69703880
69CASK0.69131178
70MAP2K30.68961745
71MAP3K110.66942565
72CAMK2A0.65683021
73PDK10.65579316
74MAP2K60.64420114
75RET0.63540268
76RAF10.63317630
77PAK30.62879713
78ICK0.62633667
79DMPK0.61772659
80MATK0.61686185
81PTK2B0.61363620
82PNCK0.60048520
83PDK40.59108005
84PDK30.59108005
85EEF2K0.59048307
86DYRK1A0.58702386
87PRKAA10.58473250
88SGK10.56028383
89RIPK10.55421352
90RPS6KA30.55136168
91GRK70.54903640
92MAPK100.52891947
93MAPK40.52347135
94TRIB30.50986150
95PDPK10.50357520
96CAMK2D0.48513803
97PRKG10.47353083
98TTN0.46830805
99CAMKK20.45619291
100RPS6KA20.45434498
101SIK10.45272438
102SGK2230.45099809
103SGK4940.45099809
104ROCK10.44935167
105TNK20.42958643
106DDR20.42729113
107AKT20.41805732
108LMTK20.41241043
109SGK30.40786089
110CAMK2B0.40694251
111MAP3K10.40678699
112MUSK0.39405414
113ADRBK10.39224277
114PRKD20.39189240
115MAPKAPK30.38750148
116PRKCZ0.36864504
117FYN0.35474293
118DAPK30.34295735
119BRAF0.34230296
120MAP2K10.33854578
121PRKACA0.33363843
122TESK10.31556217
123MAPK80.29099272

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050332.99010869
2Synaptic vesicle cycle_Homo sapiens_hsa047212.86018074
3Olfactory transduction_Homo sapiens_hsa047402.79771605
4Long-term potentiation_Homo sapiens_hsa047202.57770522
5GABAergic synapse_Homo sapiens_hsa047272.50286237
6Circadian entrainment_Homo sapiens_hsa047132.49248802
7Glutamatergic synapse_Homo sapiens_hsa047242.43147778
8Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.36531604
9Amphetamine addiction_Homo sapiens_hsa050312.26838659
10Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.22916771
11Morphine addiction_Homo sapiens_hsa050322.21279698
12Dopaminergic synapse_Homo sapiens_hsa047282.03950249
13Salivary secretion_Homo sapiens_hsa049702.02268353
14* Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.88016855
15* Oxytocin signaling pathway_Homo sapiens_hsa049211.87188965
16Insulin secretion_Homo sapiens_hsa049111.84861127
17Cholinergic synapse_Homo sapiens_hsa047251.83673776
18Gastric acid secretion_Homo sapiens_hsa049711.81088936
19Calcium signaling pathway_Homo sapiens_hsa040201.76615478
20Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.76383260
21Aldosterone synthesis and secretion_Homo sapiens_hsa049251.73851500
22Renin secretion_Homo sapiens_hsa049241.69439413
23GnRH signaling pathway_Homo sapiens_hsa049121.63140306
24Long-term depression_Homo sapiens_hsa047301.58394681
25Cocaine addiction_Homo sapiens_hsa050301.55246672
262-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.54647247
27Taste transduction_Homo sapiens_hsa047421.53284872
28Serotonergic synapse_Homo sapiens_hsa047261.52204882
29Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.47623941
30Gap junction_Homo sapiens_hsa045401.35268668
31Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.28250221
32Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.26781331
33cAMP signaling pathway_Homo sapiens_hsa040241.26540632
34Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.26372606
35Glioma_Homo sapiens_hsa052141.23314052
36Phosphatidylinositol signaling system_Homo sapiens_hsa040701.23112689
37* Cardiac muscle contraction_Homo sapiens_hsa042601.17831285
38cGMP-PKG signaling pathway_Homo sapiens_hsa040221.10340279
39* Dilated cardiomyopathy_Homo sapiens_hsa054141.09856670
40Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.09854085
41Vascular smooth muscle contraction_Homo sapiens_hsa042701.09584543
42ErbB signaling pathway_Homo sapiens_hsa040121.08850744
43Phospholipase D signaling pathway_Homo sapiens_hsa040721.08397771
44Axon guidance_Homo sapiens_hsa043601.07651557
45mTOR signaling pathway_Homo sapiens_hsa041501.05846265
46Type II diabetes mellitus_Homo sapiens_hsa049301.05676684
47Estrogen signaling pathway_Homo sapiens_hsa049151.05647133
48Melanogenesis_Homo sapiens_hsa049161.04561816
49Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.99402198
50Arginine and proline metabolism_Homo sapiens_hsa003300.97568793
51VEGF signaling pathway_Homo sapiens_hsa043700.95402797
52Oocyte meiosis_Homo sapiens_hsa041140.92238694
53Choline metabolism in cancer_Homo sapiens_hsa052310.90898720
54Dorso-ventral axis formation_Homo sapiens_hsa043200.90345455
55Collecting duct acid secretion_Homo sapiens_hsa049660.87376767
56* Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.86141772
57Alzheimers disease_Homo sapiens_hsa050100.83972649
58Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.83417796
59Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.82105049
60Thyroid hormone signaling pathway_Homo sapiens_hsa049190.81239064
61Neurotrophin signaling pathway_Homo sapiens_hsa047220.80650789
62* MAPK signaling pathway_Homo sapiens_hsa040100.80599507
63Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.80315067
64Glucagon signaling pathway_Homo sapiens_hsa049220.78086187
65Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.76168191
66* Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.75829771
67Nitrogen metabolism_Homo sapiens_hsa009100.75427228
68Rap1 signaling pathway_Homo sapiens_hsa040150.74966913
69Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.74135439
70Non-small cell lung cancer_Homo sapiens_hsa052230.73222512
71Insulin signaling pathway_Homo sapiens_hsa049100.67402083
72Arginine biosynthesis_Homo sapiens_hsa002200.67310101
73Ras signaling pathway_Homo sapiens_hsa040140.65833881
74Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.65601213
75Longevity regulating pathway - mammal_Homo sapiens_hsa042110.64359540
76Fructose and mannose metabolism_Homo sapiens_hsa000510.64275823
77Pancreatic secretion_Homo sapiens_hsa049720.62260614
78Inositol phosphate metabolism_Homo sapiens_hsa005620.62124120
79Insulin resistance_Homo sapiens_hsa049310.61233738
80Vitamin B6 metabolism_Homo sapiens_hsa007500.60068232
81Adipocytokine signaling pathway_Homo sapiens_hsa049200.59444003
82Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.57523543
83Sphingolipid signaling pathway_Homo sapiens_hsa040710.57133947
84Carbon metabolism_Homo sapiens_hsa012000.57055740
85Endocytosis_Homo sapiens_hsa041440.56176669
86Wnt signaling pathway_Homo sapiens_hsa043100.54503184
87Central carbon metabolism in cancer_Homo sapiens_hsa052300.53225655
88Circadian rhythm_Homo sapiens_hsa047100.53198146
89Endometrial cancer_Homo sapiens_hsa052130.53171096
90Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.52528698
91Renal cell carcinoma_Homo sapiens_hsa052110.51298894
92Regulation of actin cytoskeleton_Homo sapiens_hsa048100.50998445
93Carbohydrate digestion and absorption_Homo sapiens_hsa049730.50676300
94Thyroid hormone synthesis_Homo sapiens_hsa049180.50613165
95Focal adhesion_Homo sapiens_hsa045100.50515855
96Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.49982851
97Pentose phosphate pathway_Homo sapiens_hsa000300.45522590
98Alcoholism_Homo sapiens_hsa050340.44743753
99Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.44721471
100Phototransduction_Homo sapiens_hsa047440.44492243
101Ovarian steroidogenesis_Homo sapiens_hsa049130.43368859
102Tight junction_Homo sapiens_hsa045300.43266401
103Parkinsons disease_Homo sapiens_hsa050120.43099888
104Vibrio cholerae infection_Homo sapiens_hsa051100.41978683
105Prion diseases_Homo sapiens_hsa050200.40504278
106AMPK signaling pathway_Homo sapiens_hsa041520.40478358
107Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.38553608
108Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.38188023
109Thyroid cancer_Homo sapiens_hsa052160.36878087
110Bile secretion_Homo sapiens_hsa049760.36215659
111Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.36033391
112Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.35587337
113Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.35441283
114Glycerophospholipid metabolism_Homo sapiens_hsa005640.35424730
115FoxO signaling pathway_Homo sapiens_hsa040680.35211214
116Notch signaling pathway_Homo sapiens_hsa043300.32985276
117Biosynthesis of amino acids_Homo sapiens_hsa012300.29506460
118Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.29007977

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