

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139) | 5.93301873 |
| 2 | positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141) | 5.93301873 |
| 3 | regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003339 | 5.75481232 |
| 4 | negative regulation of metanephros development (GO:0072217) | 5.46957300 |
| 5 | peptidyl-histidine modification (GO:0018202) | 5.14101048 |
| 6 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 5.02448326 |
| 7 | regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307) | 4.98725967 |
| 8 | regulation of podosome assembly (GO:0071801) | 4.71455600 |
| 9 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 4.63834431 |
| 10 | negative regulation of interleukin-17 production (GO:0032700) | 4.34714840 |
| 11 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 4.26547667 |
| 12 | regulation of MHC class II biosynthetic process (GO:0045346) | 4.16839180 |
| 13 | centriole replication (GO:0007099) | 4.13797987 |
| 14 | positive regulation of interleukin-1 beta secretion (GO:0050718) | 4.00128360 |
| 15 | regulation of tyrosine phosphorylation of Stat1 protein (GO:0042510) | 3.97474970 |
| 16 | positive regulation of interleukin-1 secretion (GO:0050716) | 3.81816059 |
| 17 | positive regulation of tyrosine phosphorylation of Stat1 protein (GO:0042511) | 3.80359954 |
| 18 | regulation of interleukin-6 biosynthetic process (GO:0045408) | 3.78377205 |
| 19 | regulation of nephron tubule epithelial cell differentiation (GO:0072182) | 3.76181007 |
| 20 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.75474506 |
| 21 | organelle disassembly (GO:1903008) | 3.70219649 |
| 22 | resolution of meiotic recombination intermediates (GO:0000712) | 3.67669003 |
| 23 | proteasome assembly (GO:0043248) | 3.65138960 |
| 24 | regulation of interleukin-1 beta secretion (GO:0050706) | 3.64053209 |
| 25 | rRNA modification (GO:0000154) | 3.63086262 |
| 26 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.57502913 |
| 27 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.57502913 |
| 28 | NADH dehydrogenase complex assembly (GO:0010257) | 3.57502913 |
| 29 | regulation of vitamin D biosynthetic process (GO:0060556) | 3.56035693 |
| 30 | purine nucleobase biosynthetic process (GO:0009113) | 3.46989668 |
| 31 | cullin deneddylation (GO:0010388) | 3.45821156 |
| 32 | ether lipid metabolic process (GO:0046485) | 3.39919018 |
| 33 | ribonucleoprotein complex disassembly (GO:0032988) | 3.39214598 |
| 34 | negative regulation of neurological system process (GO:0031645) | 3.33929264 |
| 35 | DNA damage response, detection of DNA damage (GO:0042769) | 3.31506241 |
| 36 | rRNA methylation (GO:0031167) | 3.30181254 |
| 37 | respiratory chain complex IV assembly (GO:0008535) | 3.28361352 |
| 38 | regulation of epithelial cell differentiation involved in kidney development (GO:2000696) | 3.27445164 |
| 39 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.21897209 |
| 40 | microtubule polymerization or depolymerization (GO:0031109) | 3.20155709 |
| 41 | positive regulation of osteoclast differentiation (GO:0045672) | 3.20087247 |
| 42 | negative regulation of growth of symbiont in host (GO:0044130) | 3.18418081 |
| 43 | negative regulation of growth of symbiont involved in interaction with host (GO:0044146) | 3.18418081 |
| 44 | modulation of growth of symbiont involved in interaction with host (GO:0044144) | 3.18418081 |
| 45 | regulation of growth of symbiont in host (GO:0044126) | 3.18418081 |
| 46 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.17812005 |
| 47 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.17812005 |
| 48 | isotype switching (GO:0045190) | 3.17812005 |
| 49 | positive regulation of interleukin-1 beta production (GO:0032731) | 3.17153606 |
| 50 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.16932562 |
| 51 | positive regulation of chemokine biosynthetic process (GO:0045080) | 3.15708569 |
| 52 | regulation of interleukin-1 secretion (GO:0050704) | 3.15534898 |
| 53 | cellular response to gamma radiation (GO:0071480) | 3.13843527 |
| 54 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.11668877 |
| 55 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.11668877 |
| 56 | intra-S DNA damage checkpoint (GO:0031573) | 3.10673984 |
| 57 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.10668857 |
| 58 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.09178338 |
| 59 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.06634937 |
| 60 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 3.04265752 |
| 61 | nucleobase biosynthetic process (GO:0046112) | 3.02697300 |
| 62 | replication fork processing (GO:0031297) | 3.01607134 |
| 63 | positive regulation of muscle cell apoptotic process (GO:0010661) | 3.01214711 |
| 64 | protein complex biogenesis (GO:0070271) | 3.01154993 |
| 65 | negative regulation of kidney development (GO:0090185) | 2.98422257 |
| 66 | protein deneddylation (GO:0000338) | 2.97970836 |
| 67 | regulation of cytokine production involved in inflammatory response (GO:1900015) | 2.97580484 |
| 68 | regulation of smooth muscle cell apoptotic process (GO:0034391) | 2.97005552 |
| 69 | CENP-A containing nucleosome assembly (GO:0034080) | 2.95868575 |
| 70 | DNA double-strand break processing (GO:0000729) | 2.95750600 |
| 71 | regulation of interleukin-17 production (GO:0032660) | 2.95438413 |
| 72 | pseudouridine synthesis (GO:0001522) | 2.95411788 |
| 73 | DNA topological change (GO:0006265) | 2.95034736 |
| 74 | DNA ligation (GO:0006266) | 2.92141748 |
| 75 | T cell differentiation involved in immune response (GO:0002292) | 2.91903117 |
| 76 | alpha-beta T cell differentiation involved in immune response (GO:0002293) | 2.91903117 |
| 77 | alpha-beta T cell activation involved in immune response (GO:0002287) | 2.91903117 |
| 78 | reciprocal meiotic recombination (GO:0007131) | 2.91334540 |
| 79 | reciprocal DNA recombination (GO:0035825) | 2.91334540 |
| 80 | positive regulation of phosphatase activity (GO:0010922) | 2.90880269 |
| 81 | signal peptide processing (GO:0006465) | 2.87844800 |
| 82 | protein prenylation (GO:0018342) | 2.87567897 |
| 83 | prenylation (GO:0097354) | 2.87567897 |
| 84 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.87503620 |
| 85 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.87503620 |
| 86 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.87503620 |
| 87 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.86641914 |
| 88 | chromatin remodeling at centromere (GO:0031055) | 2.85615029 |
| 89 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.84382208 |
| 90 | positive regulation of isotype switching (GO:0045830) | 2.80743460 |
| 91 | positive regulation of interleukin-1 production (GO:0032732) | 2.80629926 |
| 92 | histone exchange (GO:0043486) | 2.80433804 |
| 93 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.79419287 |
| 94 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.79419287 |
| 95 | defense response to protozoan (GO:0042832) | 2.79387961 |
| 96 | RNA-dependent DNA replication (GO:0006278) | 2.78640164 |
| 97 | regulation of response to interferon-gamma (GO:0060330) | 2.77819230 |
| 98 | positive regulation of DNA recombination (GO:0045911) | 2.76263351 |
| 99 | positive regulation of interleukin-12 production (GO:0032735) | 2.75687763 |
| 100 | positive regulation of tyrosine phosphorylation of STAT protein (GO:0042531) | 2.74505560 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.59671493 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.38072347 |
| 3 | VDR_22108803_ChIP-Seq_LS180_Human | 3.13086646 |
| 4 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.07560066 |
| 5 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.01451188 |
| 6 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.85808189 |
| 7 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.84087959 |
| 8 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.74736584 |
| 9 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.56130621 |
| 10 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.46210982 |
| 11 | EWS_26573619_Chip-Seq_HEK293_Human | 2.45823803 |
| 12 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.43956846 |
| 13 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.38237985 |
| 14 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.35597177 |
| 15 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.33012852 |
| 16 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.16716844 |
| 17 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.11060785 |
| 18 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.02290617 |
| 19 | FUS_26573619_Chip-Seq_HEK293_Human | 1.99565101 |
| 20 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.98748718 |
| 21 | GATA1_22025678_ChIP-Seq_K562_Human | 1.94665713 |
| 22 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.93099617 |
| 23 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.89548165 |
| 24 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.88915917 |
| 25 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.86940181 |
| 26 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.86787917 |
| 27 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.80505738 |
| 28 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.71305575 |
| 29 | P300_19829295_ChIP-Seq_ESCs_Human | 1.70263169 |
| 30 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.64712651 |
| 31 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.60343081 |
| 32 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.57763999 |
| 33 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.57368968 |
| 34 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.52636703 |
| 35 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.49082356 |
| 36 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.48841182 |
| 37 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.47182288 |
| 38 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.46499727 |
| 39 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.42809392 |
| 40 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.42219534 |
| 41 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.41153245 |
| 42 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.40628558 |
| 43 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.39432583 |
| 44 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 1.38793163 |
| 45 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.37310703 |
| 46 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.34717659 |
| 47 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.33961246 |
| 48 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.33373617 |
| 49 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.33304070 |
| 50 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.33018597 |
| 51 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.32152636 |
| 52 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.32095656 |
| 53 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.29898704 |
| 54 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.27973735 |
| 55 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.27973735 |
| 56 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.27274328 |
| 57 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.25709069 |
| 58 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.25586160 |
| 59 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.25458135 |
| 60 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.24292890 |
| 61 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.23911041 |
| 62 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.21415004 |
| 63 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.21052954 |
| 64 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.20237437 |
| 65 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.19932338 |
| 66 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.19877139 |
| 67 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.19351373 |
| 68 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.19085247 |
| 69 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.18306779 |
| 70 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.17152814 |
| 71 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.16972360 |
| 72 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.16950816 |
| 73 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.13470135 |
| 74 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.12020070 |
| 75 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.11997881 |
| 76 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.11608835 |
| 77 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.11579859 |
| 78 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.11564128 |
| 79 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.10939754 |
| 80 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.10430876 |
| 81 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.10264596 |
| 82 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.08549138 |
| 83 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.07533252 |
| 84 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.07105898 |
| 85 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.07080193 |
| 86 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.05325904 |
| 87 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.04942055 |
| 88 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.04227603 |
| 89 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.03542138 |
| 90 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.03033172 |
| 91 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.02655036 |
| 92 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.02536578 |
| 93 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.02354683 |
| 94 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.02107733 |
| 95 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.01103555 |
| 96 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.01103555 |
| 97 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.99999681 |
| 98 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.99999681 |
| 99 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.98858987 |
| 100 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.98736573 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001835_abnormal_antigen_presentation | 4.77096310 |
| 2 | MP0004782_abnormal_surfactant_physiolog | 4.07337921 |
| 3 | MP0000372_irregular_coat_pigmentation | 3.79044266 |
| 4 | MP0001873_stomach_inflammation | 3.71437303 |
| 5 | MP0001188_hyperpigmentation | 3.29383512 |
| 6 | MP0008961_abnormal_basal_metabolism | 2.98250472 |
| 7 | MP0005671_abnormal_response_to | 2.95417800 |
| 8 | MP0009785_altered_susceptibility_to | 2.67366074 |
| 9 | MP0000569_abnormal_digit_pigmentation | 2.54352030 |
| 10 | MP0004142_abnormal_muscle_tone | 2.34020039 |
| 11 | MP0010307_abnormal_tumor_latency | 2.27283183 |
| 12 | MP0005084_abnormal_gallbladder_morpholo | 2.17586199 |
| 13 | MP0002102_abnormal_ear_morphology | 2.16013027 |
| 14 | MP0002938_white_spotting | 2.10306011 |
| 15 | MP0002933_joint_inflammation | 2.07071465 |
| 16 | MP0002138_abnormal_hepatobiliary_system | 2.05589775 |
| 17 | MP0003890_abnormal_embryonic-extraembry | 1.95763284 |
| 18 | MP0009697_abnormal_copulation | 1.91288188 |
| 19 | MP0002396_abnormal_hematopoietic_system | 1.84415905 |
| 20 | MP0003186_abnormal_redox_activity | 1.81627796 |
| 21 | MP0003786_premature_aging | 1.76965517 |
| 22 | MP0008058_abnormal_DNA_repair | 1.75620349 |
| 23 | MP0002148_abnormal_hypersensitivity_rea | 1.65698951 |
| 24 | MP0005551_abnormal_eye_electrophysiolog | 1.65402253 |
| 25 | MP0002405_respiratory_system_inflammati | 1.62366191 |
| 26 | MP0006072_abnormal_retinal_apoptosis | 1.61391938 |
| 27 | MP0005410_abnormal_fertilization | 1.57038414 |
| 28 | MP0001800_abnormal_humoral_immune | 1.48848368 |
| 29 | MP0001529_abnormal_vocalization | 1.47304673 |
| 30 | MP0003077_abnormal_cell_cycle | 1.46651867 |
| 31 | MP0008877_abnormal_DNA_methylation | 1.45243681 |
| 32 | MP0005253_abnormal_eye_physiology | 1.42723349 |
| 33 | MP0003567_abnormal_fetal_cardiomyocyte | 1.42380929 |
| 34 | MP0001293_anophthalmia | 1.42345872 |
| 35 | MP0004957_abnormal_blastocyst_morpholog | 1.40996470 |
| 36 | MP0001324_abnormal_eye_pigmentation | 1.40685551 |
| 37 | MP0002876_abnormal_thyroid_physiology | 1.40081230 |
| 38 | MP0000685_abnormal_immune_system | 1.38344917 |
| 39 | MP0006292_abnormal_olfactory_placode | 1.31161135 |
| 40 | MP0004145_abnormal_muscle_electrophysio | 1.30649474 |
| 41 | MP0010094_abnormal_chromosome_stability | 1.25189202 |
| 42 | MP0003011_delayed_dark_adaptation | 1.22576211 |
| 43 | MP0000427_abnormal_hair_cycle | 1.21288034 |
| 44 | MP0006036_abnormal_mitochondrial_physio | 1.19742765 |
| 45 | MP0005000_abnormal_immune_tolerance | 1.18935814 |
| 46 | MP0008872_abnormal_physiological_respon | 1.16027064 |
| 47 | MP0008873_increased_physiological_sensi | 1.12445460 |
| 48 | MP0008875_abnormal_xenobiotic_pharmacok | 1.10590792 |
| 49 | MP0005174_abnormal_tail_pigmentation | 1.09614447 |
| 50 | MP0008569_lethality_at_weaning | 1.08130630 |
| 51 | MP0003880_abnormal_central_pattern | 1.07673439 |
| 52 | MP0000015_abnormal_ear_pigmentation | 1.06989072 |
| 53 | MP0000579_abnormal_nail_morphology | 1.04582832 |
| 54 | MP0002736_abnormal_nociception_after | 1.02952317 |
| 55 | MP0001853_heart_inflammation | 1.02652197 |
| 56 | MP0001984_abnormal_olfaction | 1.01889632 |
| 57 | MP0002928_abnormal_bile_duct | 0.96014130 |
| 58 | MP0003111_abnormal_nucleus_morphology | 0.91664595 |
| 59 | MP0002282_abnormal_trachea_morphology | 0.90531669 |
| 60 | MP0000749_muscle_degeneration | 0.89481178 |
| 61 | MP0001348_abnormal_lacrimal_gland | 0.89285947 |
| 62 | MP0001485_abnormal_pinna_reflex | 0.88528388 |
| 63 | MP0005379_endocrine/exocrine_gland_phen | 0.88179648 |
| 64 | MP0008057_abnormal_DNA_replication | 0.87495999 |
| 65 | MP0008932_abnormal_embryonic_tissue | 0.86753395 |
| 66 | MP0002751_abnormal_autonomic_nervous | 0.85890886 |
| 67 | MP0009333_abnormal_splenocyte_physiolog | 0.85158566 |
| 68 | MP0001790_abnormal_immune_system | 0.81547588 |
| 69 | MP0005387_immune_system_phenotype | 0.81547588 |
| 70 | MP0008007_abnormal_cellular_replicative | 0.79949141 |
| 71 | MP0005645_abnormal_hypothalamus_physiol | 0.79629475 |
| 72 | MP0004885_abnormal_endolymph | 0.79106344 |
| 73 | MP0003436_decreased_susceptibility_to | 0.78227546 |
| 74 | MP0003121_genomic_imprinting | 0.76376182 |
| 75 | MP0002166_altered_tumor_susceptibility | 0.76122467 |
| 76 | MP0001119_abnormal_female_reproductive | 0.76026800 |
| 77 | MP0003787_abnormal_imprinting | 0.75446278 |
| 78 | MP0002723_abnormal_immune_serum | 0.75351564 |
| 79 | MP0009764_decreased_sensitivity_to | 0.74201163 |
| 80 | MP0003252_abnormal_bile_duct | 0.73792737 |
| 81 | MP0010155_abnormal_intestine_physiology | 0.73506729 |
| 82 | MP0001929_abnormal_gametogenesis | 0.73325211 |
| 83 | MP0003941_abnormal_skin_development | 0.72337942 |
| 84 | MP0004084_abnormal_cardiac_muscle | 0.71705421 |
| 85 | MP0000653_abnormal_sex_gland | 0.70738738 |
| 86 | MP0009765_abnormal_xenobiotic_induced | 0.69380886 |
| 87 | MP0002452_abnormal_antigen_presenting | 0.67362853 |
| 88 | MP0001177_atelectasis | 0.67226587 |
| 89 | MP0000689_abnormal_spleen_morphology | 0.66411163 |
| 90 | MP0002210_abnormal_sex_determination | 0.65523098 |
| 91 | MP0002272_abnormal_nervous_system | 0.63445354 |
| 92 | MP0002420_abnormal_adaptive_immunity | 0.63339779 |
| 93 | MP0001501_abnormal_sleep_pattern | 0.63054791 |
| 94 | MP0009046_muscle_twitch | 0.62447307 |
| 95 | MP0003195_calcinosis | 0.62164246 |
| 96 | MP0002722_abnormal_immune_system | 0.61990779 |
| 97 | MP0001958_emphysema | 0.61223617 |
| 98 | MP0001819_abnormal_immune_cell | 0.60862993 |
| 99 | MP0004484_altered_response_of | 0.60302941 |
| 100 | MP0005195_abnormal_posterior_eye | 0.59411492 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.99484169 |
| 2 | Absent/shortened dynein arms (HP:0200106) | 3.99484169 |
| 3 | Stomatitis (HP:0010280) | 3.97460015 |
| 4 | Abnormality of the labia minora (HP:0012880) | 3.94712794 |
| 5 | Nephronophthisis (HP:0000090) | 3.81005151 |
| 6 | IgG deficiency (HP:0004315) | 3.26570281 |
| 7 | Acute necrotizing encephalopathy (HP:0006965) | 3.23026155 |
| 8 | Abnormal hair whorl (HP:0010721) | 3.17716779 |
| 9 | Abnormality of the renal medulla (HP:0100957) | 3.03961531 |
| 10 | Increased CSF lactate (HP:0002490) | 2.98620973 |
| 11 | Tubular atrophy (HP:0000092) | 2.96423814 |
| 12 | Chronic otitis media (HP:0000389) | 2.96405523 |
| 13 | Hypoplasia of the uterus (HP:0000013) | 2.92205482 |
| 14 | T lymphocytopenia (HP:0005403) | 2.84095016 |
| 15 | Mitochondrial inheritance (HP:0001427) | 2.84022737 |
| 16 | Acute encephalopathy (HP:0006846) | 2.83808549 |
| 17 | Molar tooth sign on MRI (HP:0002419) | 2.83264265 |
| 18 | Abnormality of midbrain morphology (HP:0002418) | 2.83264265 |
| 19 | Irregular epiphyses (HP:0010582) | 2.81718237 |
| 20 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.76949346 |
| 21 | IgA deficiency (HP:0002720) | 2.73995136 |
| 22 | Carpal bone hypoplasia (HP:0001498) | 2.71115517 |
| 23 | Muscle fiber splitting (HP:0003555) | 2.65562892 |
| 24 | Abnormality of the renal cortex (HP:0011035) | 2.64609885 |
| 25 | Flat capital femoral epiphysis (HP:0003370) | 2.62271315 |
| 26 | Progressive inability to walk (HP:0002505) | 2.59856681 |
| 27 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.59007218 |
| 28 | Progressive macrocephaly (HP:0004481) | 2.58946428 |
| 29 | Hepatocellular necrosis (HP:0001404) | 2.57895676 |
| 30 | Abolished electroretinogram (ERG) (HP:0000550) | 2.53574088 |
| 31 | Fair hair (HP:0002286) | 2.53454564 |
| 32 | Congenital stationary night blindness (HP:0007642) | 2.43393343 |
| 33 | Cerebral edema (HP:0002181) | 2.42982202 |
| 34 | Respiratory failure (HP:0002878) | 2.41469154 |
| 35 | Leukodystrophy (HP:0002415) | 2.39658759 |
| 36 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.38830143 |
| 37 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.38830143 |
| 38 | Inability to walk (HP:0002540) | 2.36079305 |
| 39 | Abnormality of macular pigmentation (HP:0008002) | 2.34638284 |
| 40 | Decreased central vision (HP:0007663) | 2.33576799 |
| 41 | Weak cry (HP:0001612) | 2.33415087 |
| 42 | Hepatic necrosis (HP:0002605) | 2.33014237 |
| 43 | Abnormality of T cell number (HP:0011839) | 2.31650946 |
| 44 | Abnormality of lateral ventricle (HP:0030047) | 2.29654473 |
| 45 | Chronic sinusitis (HP:0011109) | 2.27086772 |
| 46 | Optic disc pallor (HP:0000543) | 2.26960574 |
| 47 | Clitoromegaly (HP:0000057) | 2.26015620 |
| 48 | Abnormal ciliary motility (HP:0012262) | 2.25701332 |
| 49 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.25534394 |
| 50 | Flat face (HP:0012368) | 2.24711198 |
| 51 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.22496569 |
| 52 | Recurrent cutaneous fungal infections (HP:0011370) | 2.22496569 |
| 53 | Abnormality of chromosome stability (HP:0003220) | 2.19505845 |
| 54 | Attenuation of retinal blood vessels (HP:0007843) | 2.17475178 |
| 55 | Type 2 muscle fiber atrophy (HP:0003554) | 2.16004803 |
| 56 | Dyschromatopsia (HP:0007641) | 2.15595341 |
| 57 | Type I transferrin isoform profile (HP:0003642) | 2.14203709 |
| 58 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.12888833 |
| 59 | Abnormality of homocysteine metabolism (HP:0010919) | 2.09138338 |
| 60 | Homocystinuria (HP:0002156) | 2.09138338 |
| 61 | Chronic hepatic failure (HP:0100626) | 2.09013248 |
| 62 | Increased serum lactate (HP:0002151) | 2.05364972 |
| 63 | Renal cortical cysts (HP:0000803) | 2.05326743 |
| 64 | Central scotoma (HP:0000603) | 2.04473153 |
| 65 | Medial flaring of the eyebrow (HP:0010747) | 2.04372942 |
| 66 | Polydipsia (HP:0001959) | 2.04365356 |
| 67 | Abnormal drinking behavior (HP:0030082) | 2.04365356 |
| 68 | 3-Methylglutaconic aciduria (HP:0003535) | 2.02637540 |
| 69 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 2.00657035 |
| 70 | Exertional dyspnea (HP:0002875) | 2.00007469 |
| 71 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.99519291 |
| 72 | Abnormality of the clitoris (HP:0000056) | 1.98067018 |
| 73 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.94051090 |
| 74 | Tubulointerstitial fibrosis (HP:0005576) | 1.93369799 |
| 75 | Constricted visual fields (HP:0001133) | 1.91919188 |
| 76 | Cone-rod dystrophy (HP:0000548) | 1.88601612 |
| 77 | Methylmalonic acidemia (HP:0002912) | 1.85334540 |
| 78 | Abnormality of the prostate (HP:0008775) | 1.84397606 |
| 79 | Generalized hypopigmentation of hair (HP:0011358) | 1.82747696 |
| 80 | Abnormality of methionine metabolism (HP:0010901) | 1.81708831 |
| 81 | Intestinal atresia (HP:0011100) | 1.81534915 |
| 82 | Retinal dysplasia (HP:0007973) | 1.80878311 |
| 83 | Abnormality of T cells (HP:0002843) | 1.79513502 |
| 84 | Anteriorly placed anus (HP:0001545) | 1.79231591 |
| 85 | Pulmonary infiltrates (HP:0002113) | 1.77638605 |
| 86 | Small hand (HP:0200055) | 1.77587330 |
| 87 | Small intestinal stenosis (HP:0012848) | 1.75318162 |
| 88 | Duodenal stenosis (HP:0100867) | 1.75318162 |
| 89 | Sloping forehead (HP:0000340) | 1.74770711 |
| 90 | Congenital, generalized hypertrichosis (HP:0004540) | 1.74252596 |
| 91 | Breast carcinoma (HP:0003002) | 1.72928631 |
| 92 | Tubulointerstitial abnormality (HP:0001969) | 1.72180342 |
| 93 | Polyuria (HP:0000103) | 1.71908384 |
| 94 | Delayed CNS myelination (HP:0002188) | 1.71328758 |
| 95 | Myelodysplasia (HP:0002863) | 1.68223005 |
| 96 | Type II lissencephaly (HP:0007260) | 1.67893312 |
| 97 | Pancreatic fibrosis (HP:0100732) | 1.67827908 |
| 98 | Hypoplasia of the fovea (HP:0007750) | 1.67018391 |
| 99 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 1.67018391 |
| 100 | Cerebellar dysplasia (HP:0007033) | 1.66443261 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EIF2AK3 | 5.30551330 |
| 2 | EIF2AK1 | 3.86931360 |
| 3 | AKT3 | 3.83554708 |
| 4 | BUB1 | 3.38132329 |
| 5 | BMPR1B | 3.34634587 |
| 6 | STK38L | 3.15507595 |
| 7 | ZAK | 2.57909647 |
| 8 | TXK | 2.46113723 |
| 9 | NUAK1 | 2.36481458 |
| 10 | MAP2K6 | 2.06613644 |
| 11 | TSSK6 | 2.01902977 |
| 12 | WNK3 | 1.93638329 |
| 13 | PKN1 | 1.91442453 |
| 14 | EIF2AK2 | 1.81433016 |
| 15 | FRK | 1.72365675 |
| 16 | MKNK1 | 1.72113415 |
| 17 | PLK3 | 1.66442867 |
| 18 | TYK2 | 1.64805822 |
| 19 | TLK1 | 1.59273564 |
| 20 | VRK1 | 1.44286151 |
| 21 | PNCK | 1.37213368 |
| 22 | MKNK2 | 1.36185166 |
| 23 | MAP3K12 | 1.35934138 |
| 24 | NME1 | 1.31625790 |
| 25 | MST4 | 1.31343661 |
| 26 | MAP3K4 | 1.26882904 |
| 27 | BMPR2 | 1.24361000 |
| 28 | ADRBK2 | 1.21248857 |
| 29 | STK3 | 1.17026373 |
| 30 | MET | 1.15480792 |
| 31 | TAOK3 | 1.15440102 |
| 32 | EPHA3 | 1.14297253 |
| 33 | EPHA4 | 1.11075809 |
| 34 | TRIM28 | 1.08500380 |
| 35 | STK24 | 1.07462017 |
| 36 | KIT | 1.03585934 |
| 37 | GRK1 | 0.99855554 |
| 38 | MAP2K4 | 0.98254984 |
| 39 | STK38 | 0.91943190 |
| 40 | DMPK | 0.86607958 |
| 41 | JAK3 | 0.85279235 |
| 42 | RPS6KA4 | 0.84062775 |
| 43 | PINK1 | 0.81273798 |
| 44 | ACVR1B | 0.77537334 |
| 45 | DYRK3 | 0.75545210 |
| 46 | TGFBR1 | 0.75066219 |
| 47 | PLK1 | 0.74807372 |
| 48 | FLT3 | 0.74550436 |
| 49 | PHKG1 | 0.72915751 |
| 50 | PHKG2 | 0.72915751 |
| 51 | MAPK15 | 0.71878176 |
| 52 | SGK2 | 0.70397038 |
| 53 | STK4 | 0.70190989 |
| 54 | BRAF | 0.67264486 |
| 55 | PLK2 | 0.67158855 |
| 56 | MINK1 | 0.67061869 |
| 57 | TTK | 0.65846480 |
| 58 | NEK1 | 0.62792159 |
| 59 | ERBB3 | 0.61323084 |
| 60 | CSNK1A1L | 0.61273480 |
| 61 | MUSK | 0.60477709 |
| 62 | PLK4 | 0.60234269 |
| 63 | WEE1 | 0.58569761 |
| 64 | CSNK1G1 | 0.58146299 |
| 65 | CDC7 | 0.57973864 |
| 66 | PAK3 | 0.54889702 |
| 67 | INSRR | 0.54212821 |
| 68 | PRKG1 | 0.52194300 |
| 69 | ADRBK1 | 0.52117771 |
| 70 | IKBKE | 0.51193823 |
| 71 | EGFR | 0.50863544 |
| 72 | CAMKK2 | 0.48789494 |
| 73 | TEC | 0.48571420 |
| 74 | OBSCN | 0.48152225 |
| 75 | CSNK1G3 | 0.48011152 |
| 76 | MAP4K2 | 0.44582377 |
| 77 | FGFR1 | 0.43623559 |
| 78 | ATR | 0.41449265 |
| 79 | MAPK13 | 0.41291229 |
| 80 | PASK | 0.41101999 |
| 81 | STK16 | 0.40315208 |
| 82 | BCR | 0.38246941 |
| 83 | FGFR2 | 0.37669289 |
| 84 | UHMK1 | 0.37541421 |
| 85 | MAP3K6 | 0.36699988 |
| 86 | MAP2K3 | 0.35572061 |
| 87 | ILK | 0.34447314 |
| 88 | AURKB | 0.33904614 |
| 89 | RPS6KA5 | 0.33421462 |
| 90 | FES | 0.32943927 |
| 91 | PRKCE | 0.32447170 |
| 92 | VRK2 | 0.32075647 |
| 93 | ATM | 0.31462840 |
| 94 | CSNK1G2 | 0.31460924 |
| 95 | IKBKB | 0.31414249 |
| 96 | JAK1 | 0.31338875 |
| 97 | IGF1R | 0.30952551 |
| 98 | CDK3 | 0.30225293 |
| 99 | CSNK2A1 | 0.29172944 |
| 100 | CSF1R | 0.25982136 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.96990673 |
| 2 | Protein export_Homo sapiens_hsa03060 | 3.88889939 |
| 3 | Allograft rejection_Homo sapiens_hsa05330 | 3.14947690 |
| 4 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.63053348 |
| 5 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.50055392 |
| 6 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.40115433 |
| 7 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.34361040 |
| 8 | Homologous recombination_Homo sapiens_hsa03440 | 2.23786530 |
| 9 | Asthma_Homo sapiens_hsa05310 | 2.23580493 |
| 10 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.14123290 |
| 11 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.13477248 |
| 12 | Steroid biosynthesis_Homo sapiens_hsa00100 | 2.06229515 |
| 13 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.02699968 |
| 14 | Basal transcription factors_Homo sapiens_hsa03022 | 1.80272619 |
| 15 | RNA degradation_Homo sapiens_hsa03018 | 1.76900053 |
| 16 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.76780795 |
| 17 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.76766958 |
| 18 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.75655067 |
| 19 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.73056213 |
| 20 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.71383515 |
| 21 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.59153269 |
| 22 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.56099950 |
| 23 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.51988553 |
| 24 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.49542035 |
| 25 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.44011662 |
| 26 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.41572354 |
| 27 | Parkinsons disease_Homo sapiens_hsa05012 | 1.40471019 |
| 28 | Mismatch repair_Homo sapiens_hsa03430 | 1.38702711 |
| 29 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.35741736 |
| 30 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.30529118 |
| 31 | RNA transport_Homo sapiens_hsa03013 | 1.14200760 |
| 32 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.13357263 |
| 33 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.13312860 |
| 34 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.11059716 |
| 35 | Base excision repair_Homo sapiens_hsa03410 | 1.10486643 |
| 36 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.07077617 |
| 37 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.05806168 |
| 38 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.05727431 |
| 39 | Phototransduction_Homo sapiens_hsa04744 | 1.03190015 |
| 40 | Viral myocarditis_Homo sapiens_hsa05416 | 1.00614207 |
| 41 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.00123251 |
| 42 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.99956661 |
| 43 | Huntingtons disease_Homo sapiens_hsa05016 | 0.96303724 |
| 44 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.95022443 |
| 45 | Spliceosome_Homo sapiens_hsa03040 | 0.94266647 |
| 46 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.92437583 |
| 47 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.91972900 |
| 48 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.90921020 |
| 49 | Ribosome_Homo sapiens_hsa03010 | 0.90462714 |
| 50 | Leishmaniasis_Homo sapiens_hsa05140 | 0.88535167 |
| 51 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.83533954 |
| 52 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.82344510 |
| 53 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.81209617 |
| 54 | RNA polymerase_Homo sapiens_hsa03020 | 0.78169627 |
| 55 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.77307622 |
| 56 | Purine metabolism_Homo sapiens_hsa00230 | 0.76575210 |
| 57 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.75619221 |
| 58 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.72946326 |
| 59 | DNA replication_Homo sapiens_hsa03030 | 0.72592317 |
| 60 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.70647911 |
| 61 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.69865512 |
| 62 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.69746460 |
| 63 | Nicotine addiction_Homo sapiens_hsa05033 | 0.69383582 |
| 64 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.68524401 |
| 65 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.67557397 |
| 66 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.65554427 |
| 67 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.64493482 |
| 68 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.64474460 |
| 69 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.63766595 |
| 70 | Measles_Homo sapiens_hsa05162 | 0.63032805 |
| 71 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.62190012 |
| 72 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.61711987 |
| 73 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.61402130 |
| 74 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.60373061 |
| 75 | Alzheimers disease_Homo sapiens_hsa05010 | 0.60204104 |
| 76 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.57536239 |
| 77 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.53428576 |
| 78 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.52256431 |
| 79 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.50507015 |
| 80 | Legionellosis_Homo sapiens_hsa05134 | 0.49260166 |
| 81 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.45776407 |
| 82 | Peroxisome_Homo sapiens_hsa04146 | 0.45226911 |
| 83 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.44908919 |
| 84 | Salmonella infection_Homo sapiens_hsa05132 | 0.44888006 |
| 85 | Cell cycle_Homo sapiens_hsa04110 | 0.44450235 |
| 86 | Malaria_Homo sapiens_hsa05144 | 0.42981100 |
| 87 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.42580757 |
| 88 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.41893445 |
| 89 | Circadian rhythm_Homo sapiens_hsa04710 | 0.41114211 |
| 90 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.40743179 |
| 91 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.38967197 |
| 92 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.38580074 |
| 93 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.37186860 |
| 94 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.37137105 |
| 95 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.35345650 |
| 96 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.34284108 |
| 97 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.33242784 |
| 98 | Retinol metabolism_Homo sapiens_hsa00830 | 0.30533351 |
| 99 | Metabolic pathways_Homo sapiens_hsa01100 | 0.30184581 |
| 100 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.29412959 |

