CAGE1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1epithelial cilium movement (GO:0003351)9.95842445
2cell wall macromolecule metabolic process (GO:0044036)9.63950309
3cell wall macromolecule catabolic process (GO:0016998)9.63950309
4plasma membrane fusion (GO:0045026)9.52291400
5piRNA metabolic process (GO:0034587)9.50373274
6acrosome reaction (GO:0007340)9.35782895
7binding of sperm to zona pellucida (GO:0007339)9.19949673
8motile cilium assembly (GO:0044458)9.14173977
9cell-cell recognition (GO:0009988)8.94100345
10cilium movement (GO:0003341)8.74270482
11reproduction (GO:0000003)8.55422830
12epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)8.30505976
13male meiosis (GO:0007140)8.23027377
14spermatid development (GO:0007286)8.08153028
15regulation of cilium movement (GO:0003352)7.50488121
16single fertilization (GO:0007338)7.16751602
17synaptonemal complex organization (GO:0070193)7.05013844
18synaptonemal complex assembly (GO:0007130)6.71316064
19DNA methylation involved in gamete generation (GO:0043046)6.64017134
20fertilization (GO:0009566)6.01869930
21sperm capacitation (GO:0048240)5.87984906
22microtubule depolymerization (GO:0007019)5.73815782
23male meiosis I (GO:0007141)5.54023111
24spermatogenesis (GO:0007283)5.45609870
25male gamete generation (GO:0048232)5.43972480
26response to pheromone (GO:0019236)5.28438525
27ventricular system development (GO:0021591)5.20443242
28chromosome organization involved in meiosis (GO:0070192)5.20174832
29gamete generation (GO:0007276)5.04720190
30DNA deamination (GO:0045006)4.80187203
31intraciliary transport (GO:0042073)4.77636176
32protein localization to cilium (GO:0061512)4.75104515
33germ cell development (GO:0007281)4.72452088
34meiotic nuclear division (GO:0007126)4.70886353
35cellular process involved in reproduction in multicellular organism (GO:0022412)4.70687187
36negative regulation of inclusion body assembly (GO:0090084)4.51549048
37organic cation transport (GO:0015695)4.47734254
38meiosis I (GO:0007127)4.38003170
39meiotic cell cycle (GO:0051321)4.33075068
40calcium ion-dependent exocytosis (GO:0017156)4.31696434
41cell recognition (GO:0008037)4.29501991
42microtubule severing (GO:0051013)4.14492130
43respiratory chain complex IV assembly (GO:0008535)4.14335281
44seminiferous tubule development (GO:0072520)4.10279171
45axoneme assembly (GO:0035082)4.07872466
46cellular ketone body metabolic process (GO:0046950)4.04102949
47centriole assembly (GO:0098534)4.02179557
48GTP biosynthetic process (GO:0006183)4.00169391
49regulation of microtubule-based movement (GO:0060632)3.93963171
50multicellular organismal reproductive process (GO:0048609)3.92941716
51L-fucose catabolic process (GO:0042355)3.90298488
52fucose catabolic process (GO:0019317)3.90298488
53L-fucose metabolic process (GO:0042354)3.90298488
54synapsis (GO:0007129)3.85448985
55cilium organization (GO:0044782)3.82776293
56left/right pattern formation (GO:0060972)3.81423991
57platelet dense granule organization (GO:0060155)3.77077943
58ketone body metabolic process (GO:1902224)3.74190753
59cilium assembly (GO:0042384)3.74178425
60regulation of inclusion body assembly (GO:0090083)3.72189432
61nucleoside diphosphate phosphorylation (GO:0006165)3.68797263
62protein polyglutamylation (GO:0018095)3.66297467
63spermatid nucleus differentiation (GO:0007289)3.65202618
64monoubiquitinated protein deubiquitination (GO:0035520)3.60612714
65centriole replication (GO:0007099)3.60423157
66cytochrome complex assembly (GO:0017004)3.58523828
67proteasome assembly (GO:0043248)3.52564124
68water-soluble vitamin biosynthetic process (GO:0042364)3.52526039
69cilium morphogenesis (GO:0060271)3.47863617
70protein complex biogenesis (GO:0070271)3.39510453
71cellular component assembly involved in morphogenesis (GO:0010927)3.34728847
72genitalia morphogenesis (GO:0035112)3.34550738
73UTP biosynthetic process (GO:0006228)3.34409971
74regulation of meiosis I (GO:0060631)3.29263373
75sequestering of actin monomers (GO:0042989)3.26394588
76regulation of hexokinase activity (GO:1903299)3.24887710
77regulation of glucokinase activity (GO:0033131)3.24887710
78G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.23006526
79multicellular organismal development (GO:0007275)3.21947532
80behavioral response to nicotine (GO:0035095)3.19324800
81DNA double-strand break processing (GO:0000729)3.19301540
82meiotic cell cycle process (GO:1903046)3.18285440
83glycerol ether metabolic process (GO:0006662)3.16825270
84protein K11-linked deubiquitination (GO:0035871)3.13595866
85lactate metabolic process (GO:0006089)3.10024363
86preassembly of GPI anchor in ER membrane (GO:0016254)3.09030493
87microtubule-based movement (GO:0007018)3.08904740
88single strand break repair (GO:0000012)3.08448541
89mitochondrial respiratory chain complex assembly (GO:0033108)3.07800009
90branched-chain amino acid catabolic process (GO:0009083)3.03892117
91ether metabolic process (GO:0018904)3.03371952
92microtubule polymerization or depolymerization (GO:0031109)3.03158648
93L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.02396801
94mitochondrial respiratory chain complex I assembly (GO:0032981)3.00983466
95NADH dehydrogenase complex assembly (GO:0010257)3.00983466
96mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.00983466
97tryptophan catabolic process (GO:0006569)2.99094515
98indole-containing compound catabolic process (GO:0042436)2.99094515
99indolalkylamine catabolic process (GO:0046218)2.99094515
100guanosine-containing compound biosynthetic process (GO:1901070)2.96014550
101polyol catabolic process (GO:0046174)2.95885166
102negative regulation of synaptic transmission, GABAergic (GO:0032229)2.94513685
103inositol phosphate catabolic process (GO:0071545)2.93960212
104phosphorylated carbohydrate dephosphorylation (GO:0046838)2.85505186
105inositol phosphate dephosphorylation (GO:0046855)2.85505186
106GPI anchor metabolic process (GO:0006505)2.85311136
107establishment of protein localization to Golgi (GO:0072600)2.84324302
108regulation of spindle checkpoint (GO:0090231)2.83696259
109gene silencing by RNA (GO:0031047)2.81117201
110protein prenylation (GO:0018342)2.80788124
111prenylation (GO:0097354)2.80788124
112left/right axis specification (GO:0070986)2.80670780
113mannosylation (GO:0097502)2.79588627
114UTP metabolic process (GO:0046051)2.78831091
115positive regulation of meiosis (GO:0045836)2.76398935
116detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.76385111
117photoreceptor cell maintenance (GO:0045494)2.75719866
118RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.73949489
119tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.73949489
120indolalkylamine metabolic process (GO:0006586)2.72633937
121L-methionine salvage (GO:0071267)2.72287499
122L-methionine biosynthetic process (GO:0071265)2.72287499
123amino acid salvage (GO:0043102)2.72287499
124positive regulation of mitochondrial fission (GO:0090141)2.71411874
125protein-cofactor linkage (GO:0018065)2.69827339
126S-adenosylmethionine metabolic process (GO:0046500)2.69378886
127keratinocyte development (GO:0003334)2.68991142
128protein targeting to Golgi (GO:0000042)2.68541066
129regulation of centriole replication (GO:0046599)2.68374970
130alditol metabolic process (GO:0019400)2.68095713
131nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.66082147
132negative regulation of transcription regulatory region DNA binding (GO:2000678)2.65843651
133cytidine deamination (GO:0009972)2.62941040
134cytidine metabolic process (GO:0046087)2.62941040
135cytidine catabolic process (GO:0006216)2.62941040
136positive regulation of meiotic cell cycle (GO:0051446)2.61872128
137protein localization to Golgi apparatus (GO:0034067)2.61280692
138DNA alkylation (GO:0006305)2.61143283
139DNA methylation (GO:0006306)2.61143283
140negative regulation of neurological system process (GO:0031645)2.59255912
141mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.57332527
142protein K6-linked ubiquitination (GO:0085020)2.56730836
143detection of light stimulus involved in visual perception (GO:0050908)2.56209857
144detection of light stimulus involved in sensory perception (GO:0050962)2.56209857
145negative regulation of cytosolic calcium ion concentration (GO:0051481)2.54318217
146proline transport (GO:0015824)2.53704240
147CTP metabolic process (GO:0046036)2.52228335
148CTP biosynthetic process (GO:0006241)2.52228335
149kynurenine metabolic process (GO:0070189)2.50888200
150chaperone-mediated protein complex assembly (GO:0051131)2.50411470
151regulation of nuclear cell cycle DNA replication (GO:0033262)2.49632425
152tryptophan metabolic process (GO:0006568)2.48606343
153protein neddylation (GO:0045116)2.48142881
154sister chromatid cohesion (GO:0007062)2.47119679
155C-terminal protein amino acid modification (GO:0018410)2.47009373
156dopamine transport (GO:0015872)2.46986648
157exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.46723846
158cellular biogenic amine catabolic process (GO:0042402)2.46714200
159amine catabolic process (GO:0009310)2.46714200
160C-terminal protein lipidation (GO:0006501)2.46623330
161transepithelial transport (GO:0070633)2.45711304
162gamma-aminobutyric acid transport (GO:0015812)2.44890928
163recombinational repair (GO:0000725)2.44389694
164double-strand break repair via homologous recombination (GO:0000724)2.43378470
165organelle assembly (GO:0070925)2.42881982
166coenzyme catabolic process (GO:0009109)2.41798611
167pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.41721849
168glycerol metabolic process (GO:0006071)2.39338977
169regulation of protein polyubiquitination (GO:1902914)2.38130584
170replicative senescence (GO:0090399)2.35155961
171protein refolding (GO:0042026)2.34863394
172DNA packaging (GO:0006323)2.27224474
173histone exchange (GO:0043486)2.26673482
174cilium or flagellum-dependent cell motility (GO:0001539)13.1818789
175fusion of sperm to egg plasma membrane (GO:0007342)12.5413185
176sperm motility (GO:0030317)10.9794575
177multicellular organism reproduction (GO:0032504)10.7240311
178axonemal dynein complex assembly (GO:0070286)10.6122108
179acrosome assembly (GO:0001675)10.4695848
180sperm-egg recognition (GO:0035036)10.0228862

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse8.25910255
2EZH2_22144423_ChIP-Seq_EOC_Human4.95118374
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.94763435
4FLI1_27457419_Chip-Seq_LIVER_Mouse3.10710441
5BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.04279862
6PCGF2_27294783_Chip-Seq_ESCs_Mouse2.84749956
7CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.78928834
8GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.73864475
9KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.72698655
10HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.55364388
11FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.44656679
12HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.41388445
13* GABP_17652178_ChIP-ChIP_JURKAT_Human2.34519453
14E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.20630475
15IGF1R_20145208_ChIP-Seq_DFB_Human2.19785232
16GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.12754774
17ZFP57_27257070_Chip-Seq_ESCs_Mouse2.10395576
18NFE2_27457419_Chip-Seq_LIVER_Mouse2.09105994
19PCGF2_27294783_Chip-Seq_NPCs_Mouse2.08398117
20SUZ12_27294783_Chip-Seq_NPCs_Mouse2.05493329
21CBX2_27304074_Chip-Seq_ESCs_Mouse2.03293089
22EST1_17652178_ChIP-ChIP_JURKAT_Human1.90141366
23EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.83676796
24VDR_22108803_ChIP-Seq_LS180_Human1.80872942
25TP53_22573176_ChIP-Seq_HFKS_Human1.79961922
26KAP1_22055183_ChIP-Seq_ESCs_Mouse1.76962842
27TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.73940817
28EWS_26573619_Chip-Seq_HEK293_Human1.72238881
29PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.72053929
30TAL1_26923725_Chip-Seq_HPCs_Mouse1.69464472
31EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.68332161
32RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.66487923
33NANOG_18555785_Chip-Seq_ESCs_Mouse1.64794896
34KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.63117452
35SALL1_21062744_ChIP-ChIP_HESCs_Human1.63076727
36EZH2_27294783_Chip-Seq_NPCs_Mouse1.62444155
37RNF2_27304074_Chip-Seq_NSC_Mouse1.62332552
38MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.61558245
39TAF15_26573619_Chip-Seq_HEK293_Human1.61421184
40P53_22387025_ChIP-Seq_ESCs_Mouse1.57582249
41BCAT_22108803_ChIP-Seq_LS180_Human1.55998301
42VDR_23849224_ChIP-Seq_CD4+_Human1.55461963
43MYC_18940864_ChIP-ChIP_HL60_Human1.55346903
44STAT1_17558387_ChIP-Seq_HELA_Human1.54695429
45NANOG_19829295_ChIP-Seq_ESCs_Human1.54458443
46SOX2_19829295_ChIP-Seq_ESCs_Human1.54458443
47ELK1_19687146_ChIP-ChIP_HELA_Human1.54138569
48STAT3_18555785_Chip-Seq_ESCs_Mouse1.53316355
49ZNF274_21170338_ChIP-Seq_K562_Hela1.51367949
50EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.50685409
51OCT4_18555785_Chip-Seq_ESCs_Mouse1.49152399
52SUZ12_18555785_Chip-Seq_ESCs_Mouse1.47315196
53P300_18555785_Chip-Seq_ESCs_Mouse1.46990041
54ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.45878753
55CRX_20693478_ChIP-Seq_RETINA_Mouse1.45511717
56KDM2B_26808549_Chip-Seq_REH_Human1.44571042
57CMYC_18555785_Chip-Seq_ESCs_Mouse1.42561543
58MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.42201074
59MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.40898683
60JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.40596072
61NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.40186680
62POU3F2_20337985_ChIP-ChIP_501MEL_Human1.39901749
63KLF4_18555785_Chip-Seq_ESCs_Mouse1.39444340
64FOXA1_25329375_ChIP-Seq_VCAP_Human1.38953969
65FOXA1_27270436_Chip-Seq_PROSTATE_Human1.38953969
66SRF_21415370_ChIP-Seq_HL-1_Mouse1.37709802
67KLF5_20875108_ChIP-Seq_MESCs_Mouse1.36853261
68E2F1_18555785_Chip-Seq_ESCs_Mouse1.36531893
69GATA1_26923725_Chip-Seq_HPCs_Mouse1.35829871
70ETV2_25802403_ChIP-Seq_MESCs_Mouse1.35776662
71RUNX1_27457419_Chip-Seq_LIVER_Mouse1.34952049
72NMYC_18555785_Chip-Seq_ESCs_Mouse1.34765146
73GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.34338130
74ESRRB_18555785_Chip-Seq_ESCs_Mouse1.32369782
75STAT3_23295773_ChIP-Seq_U87_Human1.31097834
76TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.29922791
77PU1_27457419_Chip-Seq_LIVER_Mouse1.29881819
78CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.29875027
79ZFX_18555785_Chip-Seq_ESCs_Mouse1.28867498
80CTBP2_25329375_ChIP-Seq_LNCAP_Human1.28780496
81SOX2_18555785_Chip-Seq_ESCs_Mouse1.28589528
82SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.28239145
83EGR1_23403033_ChIP-Seq_LIVER_Mouse1.27492376
84NCOR_22424771_ChIP-Seq_293T_Human1.27151983
85TCF4_22108803_ChIP-Seq_LS180_Human1.26890464
86AR_20517297_ChIP-Seq_VCAP_Human1.25705272
87OCT4_21477851_ChIP-Seq_ESCs_Mouse1.25404862
88CBP_20019798_ChIP-Seq_JUKART_Human1.25279282
89IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.25279282
90CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.25269551
91CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.24830910
92AR_25329375_ChIP-Seq_VCAP_Human1.24028139
93IRF1_19129219_ChIP-ChIP_H3396_Human1.23203631
94GBX2_23144817_ChIP-Seq_PC3_Human1.22469145
95CTCF_18555785_Chip-Seq_ESCs_Mouse1.21796802
96* PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.21757755
97MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.21085117
98SMAD4_21741376_ChIP-Seq_EPCs_Human1.19876875
99WDR5_24793694_ChIP-Seq_LNCAP_Human1.19510889
100SMAD1_18555785_Chip-Seq_ESCs_Mouse1.19448282
101ETS1_20019798_ChIP-Seq_JURKAT_Human1.18738505
102TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.18168960
103POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.18168960
104CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.18022848
105SMAD3_21741376_ChIP-Seq_EPCs_Human1.17656885
106GATA3_21878914_ChIP-Seq_MCF-7_Human1.17412590
107ER_23166858_ChIP-Seq_MCF-7_Human1.15480366
108FOXP3_21729870_ChIP-Seq_TREG_Human1.15210784
109FOXA1_21572438_ChIP-Seq_LNCaP_Human1.14987961
110ELK4_26923725_Chip-Seq_MESODERM_Mouse1.14892173
111HOXB7_26014856_ChIP-Seq_BT474_Human1.14251100
112FUS_26573619_Chip-Seq_HEK293_Human1.14234037
113NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.13697712
114CDX2_22108803_ChIP-Seq_LS180_Human1.13688637
115CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13513465
116* GATA3_21867929_ChIP-Seq_CD8_Mouse1.12771621
117NOTCH1_21737748_ChIP-Seq_TLL_Human1.12650960
118GATA3_21867929_ChIP-Seq_TH1_Mouse1.12393356
119AUTS2_25519132_ChIP-Seq_293T-REX_Human1.11977893
120PRDM14_20953172_ChIP-Seq_ESCs_Human1.11571660
121EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.10837572
122HTT_18923047_ChIP-ChIP_STHdh_Human1.10474418
123SOX2_22085726_ChIP-Seq_NPCs_Mouse1.09030556
124MYC_19829295_ChIP-Seq_ESCs_Human1.08649659
125SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.06694248
126* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.06545375
127RUNX2_22187159_ChIP-Seq_PCA_Human1.06540790
128REST_21632747_ChIP-Seq_MESCs_Mouse1.06516462
129FOXH1_21741376_ChIP-Seq_EPCs_Human1.05947797
130NR3C1_21868756_ChIP-Seq_MCF10A_Human1.05403799
131GF1_26923725_Chip-Seq_HPCs_Mouse1.03434471
132FLI1_21867929_ChIP-Seq_TH2_Mouse1.02576186
133PIAS1_25552417_ChIP-Seq_VCAP_Human1.02553317
134CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.01969290
135BMI1_23680149_ChIP-Seq_NPCS_Mouse1.01603343
136TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01391087
137SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.99969192
138SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.99850380
139GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse0.99662952
140RBPJ_21746931_ChIP-Seq_IB4_Human0.99456261
141PHF8_20622853_ChIP-Seq_HELA_Human0.98976181
142RBPJ_22232070_ChIP-Seq_NCS_Mouse0.97663949
143TCF4_23295773_ChIP-Seq_U87_Human0.97024985
144SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.95970306
145SMAD4_21799915_ChIP-Seq_A2780_Human0.95702424
146PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.94189742
147RUNX1_26923725_Chip-Seq_HPCs_Mouse0.93441108
148PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.93409142
149ERG_20517297_ChIP-Seq_VCAP_Human0.91629533
150CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.89310404
151* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.89268320
152P300_19829295_ChIP-Seq_ESCs_Human0.89182477
153SOX9_26525672_Chip-Seq_HEART_Mouse0.88527082
154PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.88180462
155GF1B_26923725_Chip-Seq_HPCs_Mouse0.88004207
156CTBP1_25329375_ChIP-Seq_LNCAP_Human0.87648720
157AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.83634506

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive5.14110899
2MP0008877_abnormal_DNA_methylation5.03985464
3MP0001929_abnormal_gametogenesis4.85819320
4MP0002210_abnormal_sex_determination3.51801579
5MP0001145_abnormal_male_reproductive2.82921508
6MP0003195_calcinosis2.77948124
7MP0002161_abnormal_fertility/fecundity2.76088816
8MP0000653_abnormal_sex_gland2.56221238
9MP0002160_abnormal_reproductive_system2.46607501
10MP0008057_abnormal_DNA_replication2.33178225
11MP0004147_increased_porphyrin_level2.31641621
12MP0002653_abnormal_ependyma_morphology2.30519802
13MP0008058_abnormal_DNA_repair2.26010238
14MP0002837_dystrophic_cardiac_calcinosis2.15797596
15MP0008875_abnormal_xenobiotic_pharmacok2.09560494
16MP0008872_abnormal_physiological_respon2.03184535
17MP0001986_abnormal_taste_sensitivity2.00706962
18MP0005410_abnormal_fertilization12.5070682
19MP0006054_spinal_hemorrhage1.82668218
20MP0001984_abnormal_olfaction1.78587623
21MP0003136_yellow_coat_color1.76510353
22MP0001188_hyperpigmentation1.70604697
23MP0006292_abnormal_olfactory_placode1.67853414
24MP0005670_abnormal_white_adipose1.60870336
25MP0005389_reproductive_system_phenotype1.60535503
26MP0002254_reproductive_system_inflammat1.60488490
27MP0008995_early_reproductive_senescence1.59781700
28MP0003786_premature_aging1.57564371
29MP0009745_abnormal_behavioral_response1.54362362
30MP0006036_abnormal_mitochondrial_physio1.52036104
31MP0002102_abnormal_ear_morphology1.50980631
32MP0000015_abnormal_ear_pigmentation1.48858435
33MP0005367_renal/urinary_system_phenotyp1.46994730
34MP0000516_abnormal_urinary_system1.46994730
35MP0009780_abnormal_chondrocyte_physiolo1.38311710
36MP0005647_abnormal_sex_gland1.34886850
37MP0010094_abnormal_chromosome_stability1.33610069
38MP0002938_white_spotting1.33201276
39MP0003121_genomic_imprinting1.32606520
40MP0008007_abnormal_cellular_replicative1.29299811
41MP0002272_abnormal_nervous_system1.28570529
42MP0001501_abnormal_sleep_pattern1.27977663
43MP0006035_abnormal_mitochondrial_morpho1.25148222
44MP0003646_muscle_fatigue1.24373501
45MP0004142_abnormal_muscle_tone1.20112981
46MP0003122_maternal_imprinting1.19776848
47MP0004145_abnormal_muscle_electrophysio1.18387738
48MP0005332_abnormal_amino_acid1.17479579
49MP0001486_abnormal_startle_reflex1.17242472
50MP0002822_catalepsy1.16195641
51MP0003186_abnormal_redox_activity1.15216472
52MP0001485_abnormal_pinna_reflex1.10963498
53MP0002572_abnormal_emotion/affect_behav1.08322892
54MP0005174_abnormal_tail_pigmentation1.07603718
55MP0002282_abnormal_trachea_morphology1.02193012
56MP0004043_abnormal_pH_regulation1.01255601
57MP0001970_abnormal_pain_threshold1.01142250
58MP0005671_abnormal_response_to1.01122343
59MP0003806_abnormal_nucleotide_metabolis1.00799466
60MP0002733_abnormal_thermal_nociception1.00191338
61MP0004924_abnormal_behavior0.99205774
62MP0005386_behavior/neurological_phenoty0.99205774
63MP0002132_abnormal_respiratory_system0.96863487
64MP0005636_abnormal_mineral_homeostasis0.96660427
65MP0009046_muscle_twitch0.95509458
66MP0000566_synostosis0.95149891
67MP0005167_abnormal_blood-brain_barrier0.94738902
68MP0004885_abnormal_endolymph0.94228146
69MP0002693_abnormal_pancreas_physiology0.92630651
70MP0001119_abnormal_female_reproductive0.91859234
71MP0005409_darkened_coat_color0.90264004
72MP0002229_neurodegeneration0.89889817
73MP0002277_abnormal_respiratory_mucosa0.89808835
74MP0009697_abnormal_copulation0.89416988
75MP0005646_abnormal_pituitary_gland0.89353592
76MP0002876_abnormal_thyroid_physiology0.88280628
77MP0005075_abnormal_melanosome_morpholog0.86887087
78MP0008775_abnormal_heart_ventricle0.86709394
79MP0001919_abnormal_reproductive_system0.86022821
80MP0000230_abnormal_systemic_arterial0.84700956
81MP0008260_abnormal_autophagy0.83524368
82MP0002751_abnormal_autonomic_nervous0.82779142
83MP0003011_delayed_dark_adaptation0.82655539
84MP0005623_abnormal_meninges_morphology0.82224997
85MP0001756_abnormal_urination0.81046809
86MP0000647_abnormal_sebaceous_gland0.80850531
87MP0004381_abnormal_hair_follicle0.80196184
88MP0002909_abnormal_adrenal_gland0.80009913
89MP0003137_abnormal_impulse_conducting0.79052400
90MP0005171_absent_coat_pigmentation0.78329288
91MP0005551_abnormal_eye_electrophysiolog0.76781011
92MP0003718_maternal_effect0.76542363
93MP0000569_abnormal_digit_pigmentation0.71943022
94MP0005253_abnormal_eye_physiology0.70866010
95MP0003878_abnormal_ear_physiology0.70003732
96MP0005377_hearing/vestibular/ear_phenot0.70003732
97MP0003787_abnormal_imprinting0.69361061
98MP0008789_abnormal_olfactory_epithelium0.68545553
99MP0002928_abnormal_bile_duct0.67604971
100MP0003111_abnormal_nucleus_morphology0.67455439
101MP0001765_abnormal_ion_homeostasis0.66809520
102MP0003699_abnormal_female_reproductive0.66457893
103MP0005394_taste/olfaction_phenotype0.65080253
104MP0005499_abnormal_olfactory_system0.65080253
105MP0002009_preneoplasia0.63353997
106MP0002736_abnormal_nociception_after0.62289514
107MP0005423_abnormal_somatic_nervous0.62042140
108MP0006072_abnormal_retinal_apoptosis0.60922252
109MP0001324_abnormal_eye_pigmentation0.59577562
110MP0005379_endocrine/exocrine_gland_phen0.58600359
111MP0000049_abnormal_middle_ear0.57237629
112MP0000026_abnormal_inner_ear0.57052644
113MP0010386_abnormal_urinary_bladder0.55499197
114MP0002095_abnormal_skin_pigmentation0.54755325
115MP0001963_abnormal_hearing_physiology0.54275571
116MP0001529_abnormal_vocalization0.53933713
117MP0001835_abnormal_antigen_presentation0.53422128
118MP0002638_abnormal_pupillary_reflex0.53398645
119MP0001968_abnormal_touch/_nociception0.53325490
120MP0004742_abnormal_vestibular_system0.52488699
121MP0006276_abnormal_autonomic_nervous0.52475621
122MP0000372_irregular_coat_pigmentation0.50564327
123MP0004134_abnormal_chest_morphology0.49994159
124MP0000631_abnormal_neuroendocrine_gland0.49053868
125MP0005084_abnormal_gallbladder_morpholo0.48869345
126MP0004808_abnormal_hematopoietic_stem0.48865987
127MP0003879_abnormal_hair_cell0.47821973
128MP0005645_abnormal_hypothalamus_physiol0.46933871
129MP0002557_abnormal_social/conspecific_i0.46737407
130MP0003941_abnormal_skin_development0.45728986
131MP0003880_abnormal_central_pattern0.45576845
132MP0002148_abnormal_hypersensitivity_rea0.44769865
133MP0002163_abnormal_gland_morphology0.44422285
134MP0003315_abnormal_perineum_morphology0.44419505
135MP0001905_abnormal_dopamine_level0.43931882
136MP0002735_abnormal_chemical_nociception0.43110577
137MP0005391_vision/eye_phenotype0.41037328
138MP0003183_abnormal_peptide_metabolism0.40933907
139MP0002405_respiratory_system_inflammati0.40684898
140MP0009785_altered_susceptibility_to0.40661567
141MP0002177_abnormal_outer_ear0.39877094
142MP0004782_abnormal_surfactant_physiolog0.39665594
143MP0000427_abnormal_hair_cycle0.39260895
144MP0001764_abnormal_homeostasis0.38546721
145MP0002234_abnormal_pharynx_morphology0.37137887

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)8.86494732
2Abnormal respiratory epithelium morphology (HP:0012253)8.54918493
3Abnormal respiratory motile cilium morphology (HP:0005938)8.54918493
4Abnormal ciliary motility (HP:0012262)7.62455672
5Rhinitis (HP:0012384)7.22431097
6Chronic bronchitis (HP:0004469)6.31946842
7Infertility (HP:0000789)5.36100650
8Nasal polyposis (HP:0100582)4.84435700
9Nephronophthisis (HP:0000090)4.43207890
10Bronchiectasis (HP:0002110)4.26044480
11Abnormality of the nasal mucosa (HP:0000433)3.82941460
12Bronchitis (HP:0012387)3.74251392
13Abnormality of the renal medulla (HP:0100957)3.50105925
14Tubulointerstitial nephritis (HP:0001970)3.46298596
15Medial flaring of the eyebrow (HP:0010747)3.45211784
16Recurrent sinusitis (HP:0011108)3.41238968
173-Methylglutaconic aciduria (HP:0003535)3.31409380
18Abnormality of midbrain morphology (HP:0002418)3.08736268
19Molar tooth sign on MRI (HP:0002419)3.08736268
20Hypothermia (HP:0002045)3.02440842
21Methylmalonic acidemia (HP:0002912)3.00651924
22Congenital stationary night blindness (HP:0007642)2.99241319
23Abnormal spermatogenesis (HP:0008669)2.94397687
24Abnormal rod and cone electroretinograms (HP:0008323)2.93063110
25Severe visual impairment (HP:0001141)2.92842103
26Acute necrotizing encephalopathy (HP:0006965)2.90327323
27Male infertility (HP:0003251)2.86490069
28Increased CSF lactate (HP:0002490)2.86440338
29Progressive macrocephaly (HP:0004481)2.85734759
30Methylmalonic aciduria (HP:0012120)2.80675131
31Acute encephalopathy (HP:0006846)2.79685371
32Mitochondrial inheritance (HP:0001427)2.77759879
33Recurrent otitis media (HP:0000403)2.73988337
34Ketoacidosis (HP:0001993)2.68548677
35Progressive inability to walk (HP:0002505)2.63861337
36Thyroiditis (HP:0100646)2.58930940
37Pancreatic fibrosis (HP:0100732)2.58926415
38Postaxial foot polydactyly (HP:0001830)2.58072645
39True hermaphroditism (HP:0010459)2.57802437
40Abolished electroretinogram (ERG) (HP:0000550)2.57641089
41Hepatocellular necrosis (HP:0001404)2.53785863
42Fibular hypoplasia (HP:0003038)2.53591501
43Gonadotropin excess (HP:0000837)2.52180384
44Hepatic necrosis (HP:0002605)2.47915765
45Abnormal mitochondria in muscle tissue (HP:0008316)2.45111225
46Hyperventilation (HP:0002883)2.42957252
47Type II lissencephaly (HP:0007260)2.42856700
48Decreased electroretinogram (ERG) amplitude (HP:0000654)2.41391126
49Pendular nystagmus (HP:0012043)2.41155180
50Ketosis (HP:0001946)2.38576690
51Congenital primary aphakia (HP:0007707)2.37283043
52Gait imbalance (HP:0002141)2.32282868
53Inability to walk (HP:0002540)2.31503869
54Azoospermia (HP:0000027)2.31374821
55Lipid accumulation in hepatocytes (HP:0006561)2.30787838
56Bony spicule pigmentary retinopathy (HP:0007737)2.27799754
57Tubulointerstitial abnormality (HP:0001969)2.26443353
58Increased hepatocellular lipid droplets (HP:0006565)2.25429020
59Congenital hepatic fibrosis (HP:0002612)2.25166867
60Nephrogenic diabetes insipidus (HP:0009806)2.22723630
61Large for gestational age (HP:0001520)2.21862920
62Median cleft lip (HP:0000161)2.19027219
63Hyperinsulinemic hypoglycemia (HP:0000825)2.18841992
64Optic disc pallor (HP:0000543)2.17812026
65Hemiparesis (HP:0001269)2.17323669
66Stomatitis (HP:0010280)2.16658794
67Abnormality of macular pigmentation (HP:0008002)2.16107637
68Intestinal atresia (HP:0011100)2.15943560
69Hypoproteinemia (HP:0003075)2.11566803
70Neoplasm of the adrenal cortex (HP:0100641)2.11178996
71Abnormality of vitamin B metabolism (HP:0004340)2.10909287
72Hyperglycinemia (HP:0002154)2.08147238
73Renal cortical cysts (HP:0000803)2.07813481
74Increased serum lactate (HP:0002151)2.06948211
75Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.06692066
76Abnormality of alanine metabolism (HP:0010916)2.06692066
77Hyperalaninemia (HP:0003348)2.06692066
78Recurrent bronchitis (HP:0002837)2.02454426
79Hypomagnesemia (HP:0002917)2.01517771
80Abnormality of the renal cortex (HP:0011035)2.01497654
81Tubular atrophy (HP:0000092)2.00665661
82Respiratory insufficiency due to defective ciliary clearance (HP:0200073)12.2532451
83Dynein arm defect of respiratory motile cilia (HP:0012255)11.6464878
84Absent/shortened dynein arms (HP:0200106)11.6464878
85Impulsivity (HP:0100710)1.99885936
86Stage 5 chronic kidney disease (HP:0003774)1.99744379
87Cerebral edema (HP:0002181)1.98670903
88Pancreatic cysts (HP:0001737)1.97078447
89Renal Fanconi syndrome (HP:0001994)1.97011382
90Abnormality of the dental root (HP:0006486)1.96972491
91Taurodontia (HP:0000679)1.96972491
92Abnormality of permanent molar morphology (HP:0011071)1.96972491
93Lactic acidosis (HP:0003128)1.96777866
94Supernumerary spleens (HP:0009799)1.96752806
95Facial cleft (HP:0002006)1.95979427
96Abnormality of molar morphology (HP:0011070)1.94264505
97Abnormality of molar (HP:0011077)1.94264505
98Renal dysplasia (HP:0000110)1.94218884
99Aplasia/Hypoplasia of the tongue (HP:0010295)1.93286718
100Gaze-evoked nystagmus (HP:0000640)1.92872655
101Lethargy (HP:0001254)1.92020741
102Sclerocornea (HP:0000647)1.90813938
103Aplasia/Hypoplasia of the lens (HP:0008063)1.89774635
104Absent rod-and cone-mediated responses on ERG (HP:0007688)1.89684060
105Postaxial hand polydactyly (HP:0001162)1.89651926
106Impaired proprioception (HP:0010831)1.89312934
107Lissencephaly (HP:0001339)1.88982597
108Abnormality of the dental pulp (HP:0006479)1.88111997
109Chromosomal breakage induced by crosslinking agents (HP:0003221)1.87797477
110Chronic sinusitis (HP:0011109)1.87658362
111Cystic liver disease (HP:0006706)1.86124510
112Poor coordination (HP:0002370)1.82131522
113Glycosuria (HP:0003076)1.81324125
114Abnormality of urine glucose concentration (HP:0011016)1.81324125
115Polyuria (HP:0000103)1.80726890
116Oculomotor apraxia (HP:0000657)1.79917781
117Abnormality of the pancreatic islet cells (HP:0006476)1.78706410
118Abnormality of endocrine pancreas physiology (HP:0012093)1.78706410
119Hypoplasia of the fovea (HP:0007750)1.77263454
120Aplasia/Hypoplasia of the fovea (HP:0008060)1.77263454
121Decreased central vision (HP:0007663)1.76903430
12211 pairs of ribs (HP:0000878)1.76243291
123Keratoconus (HP:0000563)1.75776804
124Increased corneal curvature (HP:0100692)1.75776804
125Exertional dyspnea (HP:0002875)1.75458680
126Absent speech (HP:0001344)1.74665345
127Tachypnea (HP:0002789)1.74619622
128Pachygyria (HP:0001302)1.74295239
129Abnormality of the pons (HP:0007361)1.74057470
130Hypoplasia of the capital femoral epiphysis (HP:0003090)1.74024690
131Abnormal biliary tract physiology (HP:0012439)1.73800294
132Bile duct proliferation (HP:0001408)1.73800294
133Stomach cancer (HP:0012126)1.73511407
134Broad-based gait (HP:0002136)1.73408178
135Aplasia/Hypoplasia of the fibula (HP:0006492)1.73349621
136Abnormality of dental color (HP:0011073)1.72949480
137Abnormality of DNA repair (HP:0003254)1.72775041
138Abnormality of the vitamin B12 metabolism (HP:0004341)1.72674383
139Hyperglycinuria (HP:0003108)1.71966525
140Male pseudohermaphroditism (HP:0000037)1.71786731
141Absent thumb (HP:0009777)1.71667864
142Dicarboxylic aciduria (HP:0003215)1.71599733
143Abnormality of dicarboxylic acid metabolism (HP:0010995)1.71599733
144Chromsome breakage (HP:0040012)1.67621303
145Preaxial hand polydactyly (HP:0001177)1.66365404
146Genital tract atresia (HP:0001827)1.66177685
147Vaginal atresia (HP:0000148)1.63690012
148Optic neuritis (HP:0100653)1.63481102
149Retrobulbar optic neuritis (HP:0100654)1.63481102
150Polydipsia (HP:0001959)1.62888846
151Abnormal drinking behavior (HP:0030082)1.62888846
152Degeneration of anterior horn cells (HP:0002398)1.59590118
153Abnormality of the anterior horn cell (HP:0006802)1.59590118
154Chronic hepatic failure (HP:0100626)1.58815483
155Nephropathy (HP:0000112)1.55263775
156Abnormality of dentin (HP:0010299)1.54021156
157Aplasia/Hypoplasia of the uvula (HP:0010293)1.53907814
158Occipital encephalocele (HP:0002085)1.53166206
159Aplasia/Hypoplasia of the tibia (HP:0005772)1.53143448
160Abnormality of the lower motor neuron (HP:0002366)1.53047166
161J-shaped sella turcica (HP:0002680)1.47354811
162Dyschromatopsia (HP:0007641)1.46725919
163Short tibia (HP:0005736)1.46644378
164Amyotrophic lateral sclerosis (HP:0007354)1.45480117
165Abnormality of renal resorption (HP:0011038)1.44529901
166Short ribs (HP:0000773)1.43777746
167Astigmatism (HP:0000483)1.42332497
168Ectopic kidney (HP:0000086)1.40524922
169Attenuation of retinal blood vessels (HP:0007843)1.39694398
170Abnormality of the preputium (HP:0100587)1.39483616
171Sloping forehead (HP:0000340)1.38675792
172Type 2 muscle fiber atrophy (HP:0003554)1.38588158
173Nephroblastoma (Wilms tumor) (HP:0002667)1.38477833
174Anencephaly (HP:0002323)1.37792309
175Abnormality of renal excretion (HP:0011036)1.37448461
176Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.37081306

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK37.84321296
2PDK47.84321296
3FRK5.42617763
4PDK25.18071726
5MAP4K23.62023048
6TESK13.44988415
7PRKD33.09582722
8TRIM282.43594549
9BCKDK2.39851293
10CASK2.22073398
11EIF2AK32.19317867
12MST42.17420960
13PNCK2.13667311
14NUAK12.01678396
15IRAK11.95186326
16ZAK1.89901270
17PTK2B1.85619130
18MAP3K41.84121826
19WNK41.82441379
20STK161.81711944
21STK391.70574704
22OXSR11.68999705
23IRAK21.60355028
24PLK41.60039351
25IRAK31.55754246
26MAPK151.47697479
27TLK11.44266376
28MUSK1.43515481
29STK38L1.41575675
30ACVR1B1.30173574
31ICK1.28906782
32IRAK41.25466728
33FGFR21.25186993
34CSNK1G31.19854698
35STK381.19696526
36CSNK1G21.18850267
37MAP2K71.18646682
38CSNK1G11.18630298
39PAK31.14566912
40BMPR1B1.14558794
41TNIK1.07930999
42MAP3K121.05717977
43SRPK11.04768262
44BMPR21.04482582
45TTK1.02336123
46NEK61.01263930
47NEK20.96880696
48PINK10.96276988
49BCR0.96082655
50FER0.94247223
51DYRK30.93944055
52EIF2AK10.93045801
53CCNB10.91748074
54CSNK1A1L0.90342074
55IKBKB0.85702063
56ADRBK10.85437290
57MKNK20.83156031
58EPHA30.82948104
59TXK0.82394516
60VRK20.82174322
61GRK10.80227452
62ADRBK20.79909668
63PHKG10.77745416
64PHKG20.77745416
65YES10.77531951
66DAPK20.76479608
67TAOK30.75899761
68CHEK20.75771038
69NME10.74526679
70CDK30.72022145
71AKT30.68950858
72ATR0.66563238
73STK30.64839014
74WNK10.62507533
75LIMK10.58865784
76FLT30.57305407
77EIF2AK20.56805105
78PASK0.56008139
79MAP3K140.55864575
80BRAF0.54366312
81MAPK130.52802433
82DYRK1B0.50856951
83PDK10.50427832
84SIK30.49970467
85CSNK1A10.49178102
86CAMK2D0.47523789
87MAP2K60.45801195
88MAPKAPK30.45755230
89DAPK10.45220899
90NLK0.44610090
91SGK20.44136758
92GRK50.42424253
93CLK10.39979305
94RPS6KB10.39326060
95MAPKAPK50.39290189
96WEE10.38958573
97VRK10.38594617
98ATM0.38457099
99INSRR0.37380858
100MKNK10.37191364
101TIE10.36990123
102GRK70.36811856
103MINK10.36467503
104BLK0.35794512
105STK240.35678672
106BUB10.35134873
107PLK10.34876615
108PRKCA0.34428575
109MAP2K20.33906722
110ABL10.33705225
111KDR0.33631548
112CSNK1D0.33438388
113TGFBR10.33258630
114CHEK10.32859047
115EPHA40.32103247
116ERBB30.30943949
117ITK0.30765446
118PRKCI0.29485072
119PIM20.28717078
120IGF1R0.27549234
121PRKCG0.27102160
122PRKAA20.26821923
123PRPF4B0.26182366
124CAMKK20.26098894
125MARK10.25747457
126NTRK30.25425022
127TEC0.25406818
128WNK30.24723788
129CSNK2A10.20581352
130SGK2230.17514085
131SGK4940.17514085
132PRKCQ0.16346439
133CDC70.15900002
134CAMK2A0.14707552
135DYRK20.14340461
136TNK20.14195082
137PRKG10.14166865
138BRD40.14087894
139IKBKE0.13745614
140BRSK20.13610772
141PLK30.13410838
142PKN10.12699989
143PAK10.11634354
144PIM10.10191112
145PRKD20.09795978
146PRKCE0.09120160
147KIT0.08868706
148RIPK40.08458470
149PRKACA0.07794427
150PLK20.06882520
151RPS6KA50.06664190
152PIK3CG0.05071097

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007504.57214103
2Fanconi anemia pathway_Homo sapiens_hsa034603.87785381
3Basal transcription factors_Homo sapiens_hsa030223.55887283
4Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.71116134
5Butanoate metabolism_Homo sapiens_hsa006502.44498426
6Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.39975753
7Glycolysis / Gluconeogenesis_Homo sapiens_hsa000102.31069542
8Maturity onset diabetes of the young_Homo sapiens_hsa049502.29536360
9Linoleic acid metabolism_Homo sapiens_hsa005912.25017535
10Pyruvate metabolism_Homo sapiens_hsa006202.21555018
11alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.16862458
12Huntingtons disease_Homo sapiens_hsa050162.10851953
13Nitrogen metabolism_Homo sapiens_hsa009101.92104352
14Glycosaminoglycan degradation_Homo sapiens_hsa005311.89883367
15Purine metabolism_Homo sapiens_hsa002301.89764950
16Homologous recombination_Homo sapiens_hsa034401.86792527
17Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.86621441
18Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.78303609
19Glucagon signaling pathway_Homo sapiens_hsa049221.71285584
20Propanoate metabolism_Homo sapiens_hsa006401.70503112
21Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.59949500
22Tryptophan metabolism_Homo sapiens_hsa003801.54149724
23Arachidonic acid metabolism_Homo sapiens_hsa005901.51342233
24Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.51003793
25Non-homologous end-joining_Homo sapiens_hsa034501.45774763
26Pyrimidine metabolism_Homo sapiens_hsa002401.44371443
27Peroxisome_Homo sapiens_hsa041461.42827845
28Proteasome_Homo sapiens_hsa030501.40082967
29Fatty acid biosynthesis_Homo sapiens_hsa000611.39748293
30Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.34458158
31Protein export_Homo sapiens_hsa030601.34326929
32Pentose phosphate pathway_Homo sapiens_hsa000301.33847348
33mRNA surveillance pathway_Homo sapiens_hsa030151.32204731
34Type I diabetes mellitus_Homo sapiens_hsa049401.27298079
35RNA degradation_Homo sapiens_hsa030181.26465327
36Ether lipid metabolism_Homo sapiens_hsa005651.25908349
37RNA transport_Homo sapiens_hsa030131.22429242
38Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.22342613
39Oocyte meiosis_Homo sapiens_hsa041141.22048707
40beta-Alanine metabolism_Homo sapiens_hsa004101.21914458
41Fatty acid elongation_Homo sapiens_hsa000621.17137918
42Amphetamine addiction_Homo sapiens_hsa050311.14640845
43Steroid biosynthesis_Homo sapiens_hsa001001.11675003
44Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.10129748
45Base excision repair_Homo sapiens_hsa034101.09350696
46Glycerolipid metabolism_Homo sapiens_hsa005611.09164865
47Caffeine metabolism_Homo sapiens_hsa002321.08544597
48SNARE interactions in vesicular transport_Homo sapiens_hsa041301.07464146
49Taste transduction_Homo sapiens_hsa047421.06907182
50Sulfur metabolism_Homo sapiens_hsa009201.04616844
51Collecting duct acid secretion_Homo sapiens_hsa049661.04043029
52Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.03789807
53Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.01786275
54Glycerophospholipid metabolism_Homo sapiens_hsa005641.01309377
55Dorso-ventral axis formation_Homo sapiens_hsa043201.00472056
56Sphingolipid metabolism_Homo sapiens_hsa006000.99768009
57Selenocompound metabolism_Homo sapiens_hsa004500.97636486
58Primary bile acid biosynthesis_Homo sapiens_hsa001200.97378407
59RNA polymerase_Homo sapiens_hsa030200.96524197
60Phototransduction_Homo sapiens_hsa047440.95287820
61Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.94862249
62Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.93788755
63Antigen processing and presentation_Homo sapiens_hsa046120.92839776
64Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.92261220
65Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.90512400
66Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.87824441
67DNA replication_Homo sapiens_hsa030300.85739218
68Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.85686255
69Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.85151651
70Other glycan degradation_Homo sapiens_hsa005110.83188210
71Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.82724639
72Asthma_Homo sapiens_hsa053100.82255052
73Fructose and mannose metabolism_Homo sapiens_hsa000510.81691599
74Cardiac muscle contraction_Homo sapiens_hsa042600.81241542
75Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.78364268
76Primary immunodeficiency_Homo sapiens_hsa053400.78085885
77N-Glycan biosynthesis_Homo sapiens_hsa005100.78078650
78Renin secretion_Homo sapiens_hsa049240.78002117
79Mineral absorption_Homo sapiens_hsa049780.77656727
80Nucleotide excision repair_Homo sapiens_hsa034200.77642787
81Regulation of autophagy_Homo sapiens_hsa041400.77035767
82GABAergic synapse_Homo sapiens_hsa047270.76679483
83Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.75759141
84Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.75464106
85Graft-versus-host disease_Homo sapiens_hsa053320.74886531
86Oxidative phosphorylation_Homo sapiens_hsa001900.73963791
87Nicotine addiction_Homo sapiens_hsa050330.73518715
88One carbon pool by folate_Homo sapiens_hsa006700.71983445
89Allograft rejection_Homo sapiens_hsa053300.71446265
90Autoimmune thyroid disease_Homo sapiens_hsa053200.71391227
91Spliceosome_Homo sapiens_hsa030400.70759948
92Cell cycle_Homo sapiens_hsa041100.70022207
93Calcium signaling pathway_Homo sapiens_hsa040200.69777167
94Carbohydrate digestion and absorption_Homo sapiens_hsa049730.67881498
95Cysteine and methionine metabolism_Homo sapiens_hsa002700.67704812
96Fatty acid degradation_Homo sapiens_hsa000710.66086559
97Measles_Homo sapiens_hsa051620.65805521
98Glutathione metabolism_Homo sapiens_hsa004800.64550636
99Fatty acid metabolism_Homo sapiens_hsa012120.64480268
100Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.63937727
101Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.63934655
102Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.61772074
103Rheumatoid arthritis_Homo sapiens_hsa053230.61103966
104Glutamatergic synapse_Homo sapiens_hsa047240.59017896
105Pentose and glucuronate interconversions_Homo sapiens_hsa000400.58681543
106Olfactory transduction_Homo sapiens_hsa047400.58250566
107Steroid hormone biosynthesis_Homo sapiens_hsa001400.57734938
108Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.57020307
109Fat digestion and absorption_Homo sapiens_hsa049750.56894067
110Metabolic pathways_Homo sapiens_hsa011000.56415442
111Ovarian steroidogenesis_Homo sapiens_hsa049130.54693765
112Vitamin digestion and absorption_Homo sapiens_hsa049770.53788452
113Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.53055321
114Serotonergic synapse_Homo sapiens_hsa047260.51172480
115Chemical carcinogenesis_Homo sapiens_hsa052040.50559779
116Intestinal immune network for IgA production_Homo sapiens_hsa046720.50102441
117Epstein-Barr virus infection_Homo sapiens_hsa051690.48476665
118Synaptic vesicle cycle_Homo sapiens_hsa047210.47709086
119Legionellosis_Homo sapiens_hsa051340.47080669
120ABC transporters_Homo sapiens_hsa020100.46822763
121Insulin secretion_Homo sapiens_hsa049110.46615975
122Herpes simplex infection_Homo sapiens_hsa051680.46572943
123Inositol phosphate metabolism_Homo sapiens_hsa005620.46560046
124NF-kappa B signaling pathway_Homo sapiens_hsa040640.46338111
125Mismatch repair_Homo sapiens_hsa034300.45978552
126Retinol metabolism_Homo sapiens_hsa008300.45442278
127Salivary secretion_Homo sapiens_hsa049700.44425749
128Alzheimers disease_Homo sapiens_hsa050100.44388372
129Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.42759956
130Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.42464268
131Influenza A_Homo sapiens_hsa051640.42424153
132Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.40610317
133Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.39565247
134Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.38333449
135Morphine addiction_Homo sapiens_hsa050320.36775051
136Parkinsons disease_Homo sapiens_hsa050120.35552061
137Phosphatidylinositol signaling system_Homo sapiens_hsa040700.33976068
138Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.33364676
139Circadian entrainment_Homo sapiens_hsa047130.32372435
140Circadian rhythm_Homo sapiens_hsa047100.32334895
141Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.32307318
142p53 signaling pathway_Homo sapiens_hsa041150.31744384

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