CALCRL

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1blood vessel maturation (GO:0001955)6.77684478
2positive regulation of endothelial cell differentiation (GO:0045603)6.20083870
3positive regulation of vasculogenesis (GO:2001214)6.10131414
4regulation of endothelial cell differentiation (GO:0045601)6.03185622
5lymph vessel development (GO:0001945)5.91429060
6positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141)5.75715722
7regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139)5.75715722
8lymphangiogenesis (GO:0001946)5.64775444
9regulation of vasculogenesis (GO:2001212)5.52827477
10morphogenesis of an endothelium (GO:0003159)5.44056725
11endothelial tube morphogenesis (GO:0061154)5.44056725
12surfactant homeostasis (GO:0043129)5.32286812
13negative regulation of nitric-oxide synthase activity (GO:0051001)5.27840834
14negative regulation of blood vessel endothelial cell migration (GO:0043537)5.04659142
15regulation of metalloenzyme activity (GO:0048552)4.92690744
16negative regulation of nitric oxide biosynthetic process (GO:0045019)4.83642181
17natural killer cell activation involved in immune response (GO:0002323)4.78432850
18endothelium development (GO:0003158)4.73392041
19negative regulation of endothelial cell migration (GO:0010596)4.56795197
20histamine secretion (GO:0001821)4.44865122
21protein kinase C signaling (GO:0070528)4.28945884
22retina vasculature morphogenesis in camera-type eye (GO:0061299)4.27979624
23endothelial cell differentiation (GO:0045446)4.21880138
24positive regulation of urine volume (GO:0035810)4.16230445
25vascular endothelial growth factor signaling pathway (GO:0038084)4.10737685
26chemical homeostasis within a tissue (GO:0048875)4.03432846
27Notch signaling involved in heart development (GO:0061314)4.01926106
28definitive hemopoiesis (GO:0060216)4.01448525
29regulation of establishment or maintenance of cell polarity (GO:0032878)3.88802324
30membrane raft organization (GO:0031579)3.86072556
31negative regulation of endothelial cell proliferation (GO:0001937)3.84017531
32regulation of MHC class I biosynthetic process (GO:0045343)3.78946573
33chondrocyte proliferation (GO:0035988)3.78312348
34neuron remodeling (GO:0016322)3.77756734
35lung lobe morphogenesis (GO:0060463)3.75571916
36mesodermal cell differentiation (GO:0048333)3.72012619
37positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.71752185
38negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948)3.65141317
39endothelial cell proliferation (GO:0001935)3.63614885
40heart valve formation (GO:0003188)3.62233466
41positive regulation of triglyceride lipase activity (GO:0061365)3.61691038
42positive regulation of lipoprotein lipase activity (GO:0051006)3.61691038
43histamine transport (GO:0051608)3.61501539
44substrate-dependent cell migration (GO:0006929)3.55576861
45transcytosis (GO:0045056)3.53788579
46angiogenesis involved in wound healing (GO:0060055)3.45759902
47vasculogenesis (GO:0001570)3.44519594
48antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.40544307
49negative regulation of monooxygenase activity (GO:0032769)3.40340176
50negative regulation of epithelial cell migration (GO:0010633)3.38328406
51establishment of endothelial barrier (GO:0061028)3.37191992
52vascular endothelial growth factor receptor signaling pathway (GO:0048010)3.29909443
53cellular response to vascular endothelial growth factor stimulus (GO:0035924)3.28338839
54megakaryocyte development (GO:0035855)3.26631212
55artery development (GO:0060840)3.20663373
56regulation of endothelial cell migration (GO:0010594)3.18104807
57negative regulation of platelet activation (GO:0010544)3.18072165
58endothelial cell morphogenesis (GO:0001886)3.15914007
59mRNA transcription from RNA polymerase II promoter (GO:0042789)3.14363956
60positive regulation of macrophage cytokine production (GO:0060907)3.12976960
61heart trabecula morphogenesis (GO:0061384)3.08755039
62peptidyl-tyrosine autophosphorylation (GO:0038083)3.08725621
63embryonic heart tube development (GO:0035050)3.08331603
64purine nucleotide salvage (GO:0032261)3.08169874
65T-helper 1 type immune response (GO:0042088)3.08044440
66cell migration involved in sprouting angiogenesis (GO:0002042)3.07121373
67ventricular trabecula myocardium morphogenesis (GO:0003222)3.06789753
68atrial cardiac muscle cell action potential (GO:0086014)3.06400417
69regulation of urine volume (GO:0035809)3.06316501
70basement membrane organization (GO:0071711)3.05823339
71nephron epithelium development (GO:0072009)3.04770665
72axon extension involved in axon guidance (GO:0048846)3.00740694
73neuron projection extension involved in neuron projection guidance (GO:1902284)3.00740694
74regulation of blood vessel endothelial cell migration (GO:0043535)2.99098259
75regulation of sarcomere organization (GO:0060297)2.98526260
76negative regulation of mast cell activation (GO:0033004)2.96308463
77negative regulation of angiogenesis (GO:0016525)2.95192279
78wound healing, spreading of epidermal cells (GO:0035313)2.92616461
79* angiogenesis (GO:0001525)2.90221711
80regulation of platelet activation (GO:0010543)2.90116199
81lung vasculature development (GO:0060426)2.88955458
82membrane assembly (GO:0071709)2.87801806
83glomerular filtration (GO:0003094)2.87220473
84venous blood vessel morphogenesis (GO:0048845)2.87087812
85regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.85648799
86response to interferon-alpha (GO:0035455)2.84554999
87antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.84220492
88antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.84220492
89negative regulation of blood vessel morphogenesis (GO:2000181)2.83865720
90negative regulation of DNA biosynthetic process (GO:2000279)2.83118653
91sprouting angiogenesis (GO:0002040)2.82569228
92heart trabecula formation (GO:0060347)2.81839951
93cell adhesion mediated by integrin (GO:0033627)2.80937252
94regulation of endothelial cell apoptotic process (GO:2000351)2.80750985
95positive regulation of interferon-alpha production (GO:0032727)2.80600564
96renal filtration (GO:0097205)2.79130539
97response to hyperoxia (GO:0055093)2.77949796
98response to increased oxygen levels (GO:0036296)2.77949796
99regulation of cardiac muscle cell contraction (GO:0086004)2.76486830
100regulation of RIG-I signaling pathway (GO:0039535)2.74973626
101negative regulation of systemic arterial blood pressure (GO:0003085)2.73542558
102regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030947)2.73143219
103substrate adhesion-dependent cell spreading (GO:0034446)2.72606277
104gap junction assembly (GO:0016264)2.70321659
105negative regulation of adherens junction organization (GO:1903392)2.69735755
106negative regulation of focal adhesion assembly (GO:0051895)2.69735755
107negative regulation of cell junction assembly (GO:1901889)2.69735755
108negative regulation of vasculature development (GO:1901343)2.68959061
109respiratory tube development (GO:0030323)2.68840983
110positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-2.68479892
111wound healing, spreading of cells (GO:0044319)2.67771977
112positive regulation of inositol phosphate biosynthetic process (GO:0060732)2.67123974
113positive regulation of muscle hypertrophy (GO:0014742)2.66907453
114positive regulation of cardiac muscle hypertrophy (GO:0010613)2.66907453
115negative regulation of thymocyte apoptotic process (GO:0070244)2.66073341
116mammary gland development (GO:0030879)2.66027803
117regulation of interferon-beta biosynthetic process (GO:0045357)2.65996223
118ovulation from ovarian follicle (GO:0001542)2.65887532
119regulation of germinal center formation (GO:0002634)2.65242491
120renal absorption (GO:0070293)2.64948756
121positive regulation of pathway-restricted SMAD protein phosphorylation (GO:0010862)2.64845464
122positive regulation of receptor recycling (GO:0001921)2.64815757
123response to interferon-beta (GO:0035456)2.64527286
124regulation of cell-substrate junction assembly (GO:0090109)2.64505626
125regulation of focal adhesion assembly (GO:0051893)2.64505626
126interkinetic nuclear migration (GO:0022027)2.64002925
127response to xenobiotic stimulus (GO:0009410)2.63735463
128negative regulation of endothelial cell apoptotic process (GO:2000352)2.63115568
129regulation of interferon-alpha production (GO:0032647)2.63019663
130regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)2.62251060
131patterning of blood vessels (GO:0001569)2.61928380
132regulation of establishment of cell polarity (GO:2000114)2.61239644
133regulation of endothelial cell proliferation (GO:0001936)2.60466449
134regulation of epithelial cell migration (GO:0010632)2.58309079
135blood vessel endothelial cell migration (GO:0043534)2.58284337
136blood vessel remodeling (GO:0001974)2.58173803
137positive regulation of cell junction assembly (GO:1901890)2.58086027
138positive regulation of focal adhesion assembly (GO:0051894)2.58086027
139endoderm formation (GO:0001706)2.57858872
140regulation of cell migration involved in sprouting angiogenesis (GO:0090049)2.56668816
141plasma membrane fusion (GO:0045026)2.56553075
142regulation of phospholipid biosynthetic process (GO:0071071)2.56243630
143mRNA transcription (GO:0009299)2.55988501
144mature B cell differentiation involved in immune response (GO:0002313)2.55128632
145antigen processing and presentation of endogenous antigen (GO:0019883)2.54456483
146positive regulation of endothelial cell proliferation (GO:0001938)2.54417421
147platelet dense granule organization (GO:0060155)2.52888793
148protein localization to cell surface (GO:0034394)2.52800609
149positive regulation of blood coagulation (GO:0030194)2.52178244
150positive regulation of hemostasis (GO:1900048)2.52178244
151trabecula morphogenesis (GO:0061383)2.50736379
152negative regulation of pathway-restricted SMAD protein phosphorylation (GO:0060394)2.48672007
153positive regulation of smooth muscle cell migration (GO:0014911)2.48084132
154regulation of adherens junction organization (GO:1903391)2.46921551
155endocrine hormone secretion (GO:0060986)2.46411541
156G-protein coupled receptor internalization (GO:0002031)2.45755090
157negative regulation of complement activation (GO:0045916)2.44356957
158glomerular basement membrane development (GO:0032836)2.44049625
159regulation of vascular permeability (GO:0043114)2.41513405
160negative regulation of Rho protein signal transduction (GO:0035024)2.38715553
161positive regulation of endothelial cell migration (GO:0010595)2.38233560
162vascular smooth muscle contraction (GO:0014829)2.37191929
163regulation of actin filament-based movement (GO:1903115)2.36198296

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human4.59063195
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.16130591
3GATA1_22025678_ChIP-Seq_K562_Human4.11603383
4BP1_19119308_ChIP-ChIP_Hs578T_Human4.02048925
5GATA2_21666600_ChIP-Seq_HMVEC_Human3.98981506
6IRF8_22096565_ChIP-ChIP_GC-B_Human3.94028990
7IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.49455061
8TRIM28_21343339_ChIP-Seq_HEK293_Human3.15814755
9STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.14571302
10SMAD_19615063_ChIP-ChIP_OVARY_Human2.86024482
11IRF8_21731497_ChIP-ChIP_J774_Mouse2.71574944
12CHD7_19251738_ChIP-ChIP_MESCs_Mouse2.39888055
13ZFP57_27257070_Chip-Seq_ESCs_Mouse2.35517606
14IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.32427387
15SCL_19346495_ChIP-Seq_HPC-7_Human2.28512964
16* IRF8_27001747_Chip-Seq_BMDM_Mouse2.27205233
17SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.20996578
18Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.09294995
19VDR_22108803_ChIP-Seq_LS180_Human2.07653332
20RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.07172967
21STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.97678526
22STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.96429220
23TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.92351472
24* MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.90633183
25* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.86581612
26GBX2_23144817_ChIP-Seq_PC3_Human1.85745699
27* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.84377899
28ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.83588270
29HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.79039109
30AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.78811700
31NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.78334848
32* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.74627594
33MYB_21317192_ChIP-Seq_ERMYB_Mouse1.72029542
34ZNF274_21170338_ChIP-Seq_K562_Hela1.71271787
35RUNX_20019798_ChIP-Seq_JUKART_Human1.70055767
36SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.69161817
37SOX2_20726797_ChIP-Seq_SW620_Human1.65413014
38CJUN_26792858_Chip-Seq_BT549_Human1.63679384
39P300_19829295_ChIP-Seq_ESCs_Human1.61746242
40ESR1_21235772_ChIP-Seq_MCF-7_Human1.61396954
41RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.61279251
42ESR1_20079471_ChIP-ChIP_T-47D_Human1.61248248
43CLOCK_20551151_ChIP-Seq_293T_Human1.59493747
44CDX2_19796622_ChIP-Seq_MESCs_Mouse1.56294774
45FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.55797141
46TAF15_26573619_Chip-Seq_HEK293_Human1.53583271
47SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.53534609
48TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.52014527
49* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.49948020
50TCF4_18268006_ChIP-ChIP_LS174T_Human1.47945798
51VDR_24787735_ChIP-Seq_THP-1_Human1.45757612
52ZNF217_24962896_ChIP-Seq_MCF-7_Human1.45609537
53RARG_19884340_ChIP-ChIP_MEFs_Mouse1.45328756
54SALL4_18804426_ChIP-ChIP_XEN_Mouse1.44707788
55EP300_21415370_ChIP-Seq_HL-1_Mouse1.44621870
56EED_16625203_ChIP-ChIP_MESCs_Mouse1.44424176
57NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.43372746
58AHR_22903824_ChIP-Seq_MCF-7_Human1.42601522
59PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.41612034
60PIAS1_25552417_ChIP-Seq_VCAP_Human1.40593241
61SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.39617001
62SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.39617001
63HIF1A_21447827_ChIP-Seq_MCF-7_Human1.37025871
64MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.36853028
65SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.35450765
66LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.35393536
67SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.34651165
68* SMAD4_21799915_ChIP-Seq_A2780_Human1.34194689
69SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.33910622
70CDX2_20551321_ChIP-Seq_CACO-2_Human1.33288789
71ELK3_25401928_ChIP-Seq_HUVEC_Human1.32456529
72TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.31943302
73FLI1_27457419_Chip-Seq_LIVER_Mouse1.30541939
74* PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.29579719
75GATA1_19941826_ChIP-Seq_K562_Human1.27716068
76NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.26357011
77NRF2_20460467_ChIP-Seq_MEFs_Mouse1.26357011
78SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.25553621
79EZH2_22144423_ChIP-Seq_EOC_Human1.24881058
80PPAR_26484153_Chip-Seq_NCI-H1993_Human1.24733094
81SMAD3_21741376_ChIP-Seq_EPCs_Human1.24612071
82EZH2_18974828_ChIP-Seq_MESCs_Mouse1.24549271
83RNF2_18974828_ChIP-Seq_MESCs_Mouse1.24549271
84NR3C1_23031785_ChIP-Seq_PC12_Mouse1.24513430
85MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.24144488
86STAT3_23295773_ChIP-Seq_U87_Human1.23759869
87FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.22892328
88SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.22674835
89BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.20385442
90STAT4_19710469_ChIP-ChIP_TH1__Mouse1.20339762
91UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.19471491
92GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.17651960
93BRD4_25478319_ChIP-Seq_HGPS_Human1.16358171
94MTF2_20144788_ChIP-Seq_MESCs_Mouse1.15939923
95* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15104647
96* CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.14907292
97EGR1_19374776_ChIP-ChIP_THP-1_Human1.14819449
98FUS_26573619_Chip-Seq_HEK293_Human1.14359678
99TOP2B_26459242_ChIP-Seq_MCF-7_Human1.13292879
100TP53_18474530_ChIP-ChIP_U2OS_Human1.12138056
101SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.11057051
102* NR3C1_21868756_ChIP-Seq_MCF10A_Human1.10542201
103WT1_19549856_ChIP-ChIP_CCG9911_Human1.10179963
104TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.09980508
105* TCF4_22108803_ChIP-Seq_LS180_Human1.09695886
106PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.09426066
107* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.08913042
108ESR2_21235772_ChIP-Seq_MCF-7_Human1.08642461
109* AR_25329375_ChIP-Seq_VCAP_Human1.08225882
110RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.07645722
111FOXM1_26456572_ChIP-Seq_MCF-7_Human1.07035731
112SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.06791498
113WT1_25993318_ChIP-Seq_PODOCYTE_Human1.05953871
114ARNT_22903824_ChIP-Seq_MCF-7_Human1.05532556
115TCF4_23295773_ChIP-Seq_U87_Human1.04731379
116GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.04230181
117EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.04189862
118IGF1R_20145208_ChIP-Seq_DFB_Human1.02825681
119BCAT_22108803_ChIP-Seq_LS180_Human1.01648837
120CTBP2_25329375_ChIP-Seq_LNCAP_Human1.01227473
121KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.00915332
122FLI1_21867929_ChIP-Seq_TH2_Mouse1.00122445
123FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.99946556
124RUNX2_22187159_ChIP-Seq_PCA_Human0.99495300
125CDX2_22108803_ChIP-Seq_LS180_Human0.98855332
126PCGF2_27294783_Chip-Seq_ESCs_Mouse0.98692008
127TP53_16413492_ChIP-PET_HCT116_Human0.98078619
128JARID2_20064375_ChIP-Seq_MESCs_Mouse0.97796890
129EZH2_27294783_Chip-Seq_NPCs_Mouse0.97791408
130GATA2_19941826_ChIP-Seq_K562_Human0.96064564
131ER_23166858_ChIP-Seq_MCF-7_Human0.95261141
132AR_21572438_ChIP-Seq_LNCaP_Human0.94689516
133RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.94658775
134* LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94601503
135* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.94006025
136RXR_22108803_ChIP-Seq_LS180_Human0.93740959
137* NANOG_18555785_Chip-Seq_ESCs_Mouse0.93681057
138STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.93275949
139* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.92800726
140KDM2B_26808549_Chip-Seq_REH_Human0.92692224
141SPI1_23127762_ChIP-Seq_K562_Human0.92366317
142NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.91774761
143SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.91637159
144* TBX20_22080862_ChIP-Seq_HEART_Mouse0.90720340
145* TBX20_22328084_ChIP-Seq_HEART_Mouse0.90720340
146FOXO3_23340844_ChIP-Seq_DLD1_Human0.90613650
147STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.89019431
148JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.87896266
149MYB_26560356_Chip-Seq_TH2_Human0.87165769
150STAT6_21828071_ChIP-Seq_BEAS2B_Human0.87110148
151TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.86938662
152GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.86493673
153JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.86172998
154* TP63_23658742_ChIP-Seq_EP156T_Human0.85216706
155PU_27001747_Chip-Seq_BMDM_Mouse0.83223497
156SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.82718932
157VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.82334129
158OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.81292664
159SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.78872375
160SMAD3_21741376_ChIP-Seq_HESCs_Human0.78588340
161PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.78153598
162PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.77872451
163SOX9_24532713_ChIP-Seq_HFSC_Mouse0.77689239

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001879_abnormal_lymphatic_vessel5.25644393
2MP0010368_abnormal_lymphatic_system5.10546783
3MP0003191_abnormal_cellular_cholesterol4.46814116
4MP0003724_increased_susceptibility_to4.33002635
5MP0006054_spinal_hemorrhage4.12104023
6MP0003828_pulmonary_edema3.71989677
7MP0005360_urolithiasis3.66142552
8MP0005167_abnormal_blood-brain_barrier3.32921870
9MP0003950_abnormal_plasma_membrane3.05383067
10MP0004272_abnormal_basement_membrane2.96303115
11MP0002138_abnormal_hepatobiliary_system2.77251765
12MP0009780_abnormal_chondrocyte_physiolo2.41426415
13MP0003705_abnormal_hypodermis_morpholog2.38923037
14MP0004782_abnormal_surfactant_physiolog2.25309267
15MP0002332_abnormal_exercise_endurance2.16678168
16MP0004883_abnormal_blood_vessel2.11592612
17MP0001958_emphysema2.03498555
18MP0000465_gastrointestinal_hemorrhage1.97759698
19MP0005084_abnormal_gallbladder_morpholo1.96165498
20MP0004084_abnormal_cardiac_muscle1.93379877
21MP0009785_altered_susceptibility_to1.89713211
22MP0003045_fibrosis1.87421331
23MP0008004_abnormal_stomach_pH1.85009386
24MP0000343_altered_response_to1.80554565
25MP0001853_heart_inflammation1.79146381
26MP0003279_aneurysm1.79122925
27MP0000249_abnormal_blood_vessel1.77350017
28MP0004484_altered_response_of1.71812553
29* MP0000767_abnormal_smooth_muscle1.71622096
30MP0005164_abnormal_response_to1.71484586
31MP0002933_joint_inflammation1.69083281
32MP0006138_congestive_heart_failure1.68385083
33MP0009697_abnormal_copulation1.67609441
34MP0004215_abnormal_myocardial_fiber1.62947425
35MP0004885_abnormal_endolymph1.57590857
36MP0005623_abnormal_meninges_morphology1.52843465
37MP0001835_abnormal_antigen_presentation1.51948848
38MP0005595_abnormal_vascular_smooth1.49695304
39MP0003075_altered_response_to1.49478437
40MP0004147_increased_porphyrin_level1.44680887
41MP0009764_decreased_sensitivity_to1.43596355
42MP0005409_darkened_coat_color1.35968819
43MP0005165_increased_susceptibility_to1.34796815
44MP0003091_abnormal_cell_migration1.32262922
45MP0008775_abnormal_heart_ventricle1.32114098
46MP0000013_abnormal_adipose_tissue1.29399487
47MP0002132_abnormal_respiratory_system1.27884977
48MP0002254_reproductive_system_inflammat1.23701441
49MP0004036_abnormal_muscle_relaxation1.22197675
50MP0005464_abnormal_platelet_physiology1.20520938
51MP0002133_abnormal_respiratory_system1.20070231
52MP0005388_respiratory_system_phenotype1.20070231
53MP0004145_abnormal_muscle_electrophysio1.18571517
54MP0001915_intracranial_hemorrhage1.17873943
55MP0005397_hematopoietic_system_phenotyp1.16994901
56MP0001545_abnormal_hematopoietic_system1.16994901
57MP0002419_abnormal_innate_immunity1.15486115
58MP0002166_altered_tumor_susceptibility1.15458786
59MP0001533_abnormal_skeleton_physiology1.13619437
60MP0002148_abnormal_hypersensitivity_rea1.12660614
61MP0002405_respiratory_system_inflammati1.12455942
62MP0009278_abnormal_bone_marrow1.12114719
63MP0005171_absent_coat_pigmentation1.09855502
64MP0005671_abnormal_response_to1.09675994
65MP0002877_abnormal_melanocyte_morpholog1.08261185
66MP0002638_abnormal_pupillary_reflex1.07721859
67MP0004085_abnormal_heartbeat1.07664333
68MP0005670_abnormal_white_adipose1.07256190
69MP0003566_abnormal_cell_adhesion1.04196763
70MP0001851_eye_inflammation1.04120216
71* MP0005385_cardiovascular_system_phenoty1.03301195
72* MP0001544_abnormal_cardiovascular_syste1.03301195
73MP0005025_abnormal_response_to1.02963824
74MP0008438_abnormal_cutaneous_collagen1.02637695
75MP0001542_abnormal_bone_strength1.01969610
76MP0005387_immune_system_phenotype1.00279728
77MP0001790_abnormal_immune_system1.00279728
78MP0002128_abnormal_blood_circulation0.99793251
79MP0003252_abnormal_bile_duct0.97413828
80MP0003943_abnormal_hepatobiliary_system0.95940772
81MP0002925_abnormal_cardiovascular_devel0.95612497
82MP0000685_abnormal_immune_system0.92490899
83MP0010030_abnormal_orbit_morphology0.91911794
84MP0005620_abnormal_muscle_contractility0.89738969
85MP0001986_abnormal_taste_sensitivity0.88701652
86* MP0001614_abnormal_blood_vessel0.88282550
87MP0003868_abnormal_feces_composition0.88090166
88MP0004510_myositis0.87277262
89MP0002295_abnormal_pulmonary_circulatio0.87087541
90MP0002127_abnormal_cardiovascular_syste0.86471813
91MP0005000_abnormal_immune_tolerance0.86322064
92MP0002452_abnormal_antigen_presenting0.85632870
93MP0005023_abnormal_wound_healing0.85223769
94MP0005275_abnormal_skin_tensile0.84853289
95MP0002723_abnormal_immune_serum0.84719991
96MP0002972_abnormal_cardiac_muscle0.84638085
97* MP0010155_abnormal_intestine_physiology0.83907495
98MP0003436_decreased_susceptibility_to0.81633216
99* MP0001784_abnormal_fluid_regulation0.80553384
100MP0002006_tumorigenesis0.80090687
101MP0003448_altered_tumor_morphology0.79592112
102MP0005503_abnormal_tendon_morphology0.79451273
103MP0003303_peritoneal_inflammation0.79306636
104MP0003300_gastrointestinal_ulcer0.78459075
105MP0001175_abnormal_lung_morphology0.78444364
106MP0001819_abnormal_immune_cell0.76322848
107MP0003633_abnormal_nervous_system0.75677124
108MP0003646_muscle_fatigue0.75311837
109MP0002420_abnormal_adaptive_immunity0.75255520
110MP0005187_abnormal_penis_morphology0.73304735
111MP0001881_abnormal_mammary_gland0.72137867
112MP0002168_other_aberrant_phenotype0.71474742
113* MP0000266_abnormal_heart_morphology0.70316208
114MP0000230_abnormal_systemic_arterial0.69905990
115MP0001800_abnormal_humoral_immune0.69652182
116* MP0003567_abnormal_fetal_cardiomyocyte0.69589886
117MP0006082_CNS_inflammation0.68995901
118MP0000383_abnormal_hair_follicle0.68076224
119MP0004808_abnormal_hematopoietic_stem0.66727307
120MP0001845_abnormal_inflammatory_respons0.66022139
121MP0001501_abnormal_sleep_pattern0.65983562
122MP0008469_abnormal_protein_level0.65823660
123MP0001486_abnormal_startle_reflex0.65609415
124MP0003011_delayed_dark_adaptation0.64547799
125MP0005551_abnormal_eye_electrophysiolog0.64409128
126MP0010630_abnormal_cardiac_muscle0.63268206
127MP0006276_abnormal_autonomic_nervous0.63263248
128MP0003283_abnormal_digestive_organ0.62858429
129MP0000681_abnormal_thyroid_gland0.61822824
130MP0005166_decreased_susceptibility_to0.61682363
131MP0003638_abnormal_response/metabolism_0.60799252
132MP0004130_abnormal_muscle_cell0.59616322
133MP0005266_abnormal_metabolism0.59096998
134MP0003690_abnormal_glial_cell0.58421682
135MP0001485_abnormal_pinna_reflex0.56033311
136MP0010352_gastrointestinal_tract_polyps0.55843916
137MP0003941_abnormal_skin_development0.55617054
138MP0005330_cardiomyopathy0.53138194
139MP0001756_abnormal_urination0.52494960
140MP0005365_abnormal_bile_salt0.51505239
141MP0005253_abnormal_eye_physiology0.51113504
142MP0003385_abnormal_body_wall0.46098463
143MP0002108_abnormal_muscle_morphology0.44460411
144MP0003935_abnormal_craniofacial_develop0.44031690
145MP0003631_nervous_system_phenotype0.43782016
146MP0003195_calcinosis0.42647250

Predicted human phenotypes

RankGene SetZ-score
1Spontaneous hematomas (HP:0007420)6.65942451
2Hematochezia (HP:0002573)6.24572442
3Polycythemia (HP:0001901)5.93349553
4Autoimmune thrombocytopenia (HP:0001973)5.34211493
5Adactyly (HP:0009776)4.79401320
6Abnormality of the nasal mucosa (HP:0000433)4.55512359
7Interstitial pulmonary disease (HP:0006530)4.15253750
8Autoimmune hemolytic anemia (HP:0001890)4.08689467
9Esophageal varix (HP:0002040)4.07828909
10Reduced subcutaneous adipose tissue (HP:0003758)3.94439307
11Arterial tortuosity (HP:0005116)3.88877166
12Congenital, generalized hypertrichosis (HP:0004540)3.81802826
13Conjunctival telangiectasia (HP:0000524)3.75896318
14Skull defect (HP:0001362)3.73827944
15Growth hormone excess (HP:0000845)3.73124201
16Cerebral hemorrhage (HP:0001342)3.60519396
17Pigmentary retinal degeneration (HP:0001146)3.54981634
18Wrist flexion contracture (HP:0001239)3.52235921
19Colitis (HP:0002583)3.49238345
20Mucosal telangiectasiae (HP:0100579)3.46197996
21Xerostomia (HP:0000217)3.41373016
22Glucose intolerance (HP:0000833)3.41183938
23Abnormality of the vasculature of the conjunctiva (HP:0008054)3.38505809
24Eczematoid dermatitis (HP:0000976)3.33878980
25Enlarged penis (HP:0000040)3.32252426
26Myositis (HP:0100614)3.26582003
27Mesangial abnormality (HP:0001966)3.20349112
28Abnormality of B cell number (HP:0010975)3.17400556
29B lymphocytopenia (HP:0010976)3.17400556
30Increased IgE level (HP:0003212)3.16024413
31Myotonia (HP:0002486)3.05222470
32Nonimmune hydrops fetalis (HP:0001790)3.04825563
33Eosinophilia (HP:0001880)3.04478649
34Orchitis (HP:0100796)3.02620979
35Pulmonary infiltrates (HP:0002113)3.01680245
36Thyroiditis (HP:0100646)3.00593262
37Facial diplegia (HP:0001349)2.94207359
38Portal hypertension (HP:0001409)2.91331212
39Microcytic anemia (HP:0001935)2.88693026
40Vascular tortuosity (HP:0004948)2.81643185
41Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.81233549
42Short 4th metacarpal (HP:0010044)2.81233549
43Pulmonary hypertension (HP:0002092)2.80538508
44Pulmonary artery stenosis (HP:0004415)2.79813073
45Hypoglycemic seizures (HP:0002173)2.72203427
46Prolonged bleeding time (HP:0003010)2.70748508
47Striae distensae (HP:0001065)2.70423887
48Abnormal glucose tolerance (HP:0001952)2.70202358
49Abnormality of the hepatic vasculature (HP:0006707)2.68674152
50Aortic aneurysm (HP:0004942)2.65634456
51Hemiplegia (HP:0002301)2.65559542
52Pulmonary embolism (HP:0002204)2.63783279
53Stenosis of the external auditory canal (HP:0000402)2.63368916
54Hemoptysis (HP:0002105)2.59095376
55Cerebral aneurysm (HP:0004944)2.58685578
56Tetraparesis (HP:0002273)2.58664509
57Increased corneal curvature (HP:0100692)2.54529877
58Keratoconus (HP:0000563)2.54529877
59Camptodactyly of toe (HP:0001836)2.53740135
60Hyperventilation (HP:0002883)2.49993232
61Elevated erythrocyte sedimentation rate (HP:0003565)2.49724756
62Recurrent abscess formation (HP:0002722)2.48910646
63Abnormality of the 4th metacarpal (HP:0010012)2.45910865
64Severe combined immunodeficiency (HP:0004430)2.45560113
65Segmental peripheral demyelination/remyelination (HP:0003481)2.45194174
66Abnormality of the pulmonary veins (HP:0011718)2.45036371
67Atrial fibrillation (HP:0005110)2.44443723
68Abnormality of eosinophils (HP:0001879)2.42973315
69Deep venous thrombosis (HP:0002625)2.42914387
70Aortic valve stenosis (HP:0001650)2.42409635
71J-shaped sella turcica (HP:0002680)2.40712182
72Visceral angiomatosis (HP:0100761)2.40078392
73Optic neuritis (HP:0100653)2.38949534
74Retrobulbar optic neuritis (HP:0100654)2.38949534
75Subacute progressive viral hepatitis (HP:0006572)2.38298512
76Hyporeflexia of lower limbs (HP:0002600)2.36854854
77Inflammation of the large intestine (HP:0002037)2.36711783
78Aortic dissection (HP:0002647)2.36248779
79Cavernous hemangioma (HP:0001048)2.34529490
80Granulocytopenia (HP:0001913)2.33289564
81Intestinal atresia (HP:0011100)2.33230311
82Supraventricular arrhythmia (HP:0005115)2.33033702
83Hemangiomatosis (HP:0007461)2.31908028
84Recurrent fungal infections (HP:0002841)2.31690567
85Hydroureter (HP:0000072)2.26460958
86Hyperinsulinemic hypoglycemia (HP:0000825)2.25902876
87Recurrent gram-negative bacterial infections (HP:0005420)2.25726945
88Capillary hemangiomas (HP:0005306)2.24404797
89Overgrowth (HP:0001548)2.23839870
90Hypoglycemic coma (HP:0001325)2.23468273
91Joint contractures involving the joints of the feet (HP:0100492)2.19974348
92Flexion contracture of toe (HP:0005830)2.19974348
93Recurrent viral infections (HP:0004429)2.19869166
94Abnormality of the right ventricle (HP:0001707)2.19604324
95Occipital encephalocele (HP:0002085)2.18505296
96Leukocytosis (HP:0001974)2.17306996
97Abnormal umbilical cord blood vessels (HP:0011403)2.17156478
98Single umbilical artery (HP:0001195)2.17156478
99Abnormality of the fetal cardiovascular system (HP:0010948)2.17156478
100Primary atrial arrhythmia (HP:0001692)2.16760399
101Muscle fiber splitting (HP:0003555)2.16109119
102Abnormality of the intrinsic pathway (HP:0010989)2.16050389
103Bulbous nose (HP:0000414)2.15218487
104Atrioventricular block (HP:0001678)2.14977057
105Gastrointestinal inflammation (HP:0004386)2.13487050
106Limited hip movement (HP:0008800)2.12958162
107Hemiparesis (HP:0001269)2.12861757
108Epistaxis (HP:0000421)2.11607319
109Exotropia (HP:0000577)2.10885201
110Bone cyst (HP:0012062)2.10669729
111Delayed CNS myelination (HP:0002188)2.10369177
112Chronic otitis media (HP:0000389)2.09989181
113Abnormality of the periventricular white matter (HP:0002518)2.08971558
114Hypercholesterolemia (HP:0003124)2.08801593
115Hepatosplenomegaly (HP:0001433)2.08717343
116Abnormality of the ischium (HP:0003174)2.08675947
117Thick nail (HP:0001805)2.07867069
118Hip contracture (HP:0003273)2.07713892
119Protrusio acetabuli (HP:0003179)2.07177082
120Lymphangioma (HP:0100764)2.06717060
121Thrombophlebitis (HP:0004418)2.06528550
122Myocardial infarction (HP:0001658)2.06032292
123Porencephaly (HP:0002132)2.05729862
124Stroke (HP:0001297)2.05043691
125Teleangiectasia of the skin (HP:0100585)2.03579227
126Large hands (HP:0001176)2.03351172
127Abnormal platelet volume (HP:0011876)2.03193607
128Osteolytic defects of the hand bones (HP:0009699)2.02672518
129Osteolytic defects of the phalanges of the hand (HP:0009771)2.02672518
130Congenital hepatic fibrosis (HP:0002612)2.02280673
131Increased mean platelet volume (HP:0011877)2.00994761
132Annular pancreas (HP:0001734)2.00875791
133Prominent supraorbital ridges (HP:0000336)2.00467425
134Supraventricular tachycardia (HP:0004755)1.99003221
135Aplasia cutis congenita (HP:0001057)1.98614666
136Decreased circulating renin level (HP:0003351)1.96425221
137Insulin-resistant diabetes mellitus (HP:0000831)1.95159987
138Orthostatic hypotension (HP:0001278)1.94675959
139Joint hemorrhage (HP:0005261)1.93835104
140Combined immunodeficiency (HP:0005387)1.92797204
141Absent hand (HP:0004050)1.92547828
142Cutaneous finger syndactyly (HP:0010554)1.90091251
143Congenital stationary night blindness (HP:0007642)1.89403168
144Acanthosis nigricans (HP:0000956)1.89258459
145Chondrocalcinosis (HP:0000934)1.88805793
146Hemorrhage of the eye (HP:0011885)1.88553793
147Hypoplastic left heart (HP:0004383)1.87971178
148Purpura (HP:0000979)1.87896597
149Pancreatic islet-cell hyperplasia (HP:0004510)1.86309259
150Mitral valve prolapse (HP:0001634)1.85639239
151Recurrent bacterial skin infections (HP:0005406)1.85057854
152Abnormality of macrophages (HP:0004311)1.84486404
153Heart block (HP:0012722)1.84125183
154Menorrhagia (HP:0000132)1.83740790
155Abnormality of Sharpey fibers (HP:0100685)1.82906145
156Urethral obstruction (HP:0000796)1.82894306
157Keratoconjunctivitis sicca (HP:0001097)1.82459445
158Long foot (HP:0001833)1.80378310
159Tubular atrophy (HP:0000092)1.80239274
160Anterior segment dysgenesis (HP:0007700)1.80136925
161Abnormality of the anterior chamber (HP:0000593)1.76257005
162Tachypnea (HP:0002789)1.72957598
163Hypoplasia of the iris (HP:0007676)1.72355257
164Scotoma (HP:0000575)1.72277352
165Accelerated skeletal maturation (HP:0005616)1.71993415
166Fair hair (HP:0002286)1.70409327
167Abnormal atrioventricular conduction (HP:0005150)1.69436883
168Venous insufficiency (HP:0005293)1.69420660
169Limb dystonia (HP:0002451)1.67744057

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TGFBR24.36241112
2TGFBR13.66953176
3KDR3.23897925
4MAP3K142.47913565
5PDK22.39062361
6TEC2.03338292
7TIE110.3292676
8AKT31.76551620
9IRAK41.69953873
10BMPR1B1.65592778
11EPHB21.64924218
12MST41.55644888
13TBK11.52013578
14EPHB11.49178116
15CSK1.48532996
16FER1.47344489
17PTK61.46584578
18GRK11.44913870
19KIT1.44519951
20IKBKE1.34809487
21PAK41.34784601
22MYLK1.28776755
23TYK21.23306178
24NEK61.20085669
25JAK31.17840304
26NEK91.17835830
27PTK2B1.14985213
28FGFR31.14805780
29ERN11.14493051
30FGFR41.13719299
31MAP3K61.11549383
32NTRK11.01295186
33GRK71.00516384
34TXK0.93938193
35CHUK0.89825363
36PTK20.89533294
37YES10.87826949
38STK100.87060320
39MATK0.85981497
40MAPK120.83542186
41ACVR1B0.83010601
42RIPK10.80561856
43MAP4K10.79687884
44JAK10.78530375
45MAP2K30.78476636
46EPHA30.76130896
47MET0.74475522
48MAPK70.68088020
49MARK30.67459178
50MKNK20.67411375
51PIK3CG0.67036940
52STK390.66857401
53NUAK10.64800396
54PDGFRB0.64513125
55MAP4K20.64206547
56MAPKAPK30.62694507
57TRPM70.60021906
58IKBKB0.59818062
59FES0.57310772
60IRAK30.56677346
61DMPK0.56656903
62LRRK20.55855267
63PKN10.55852015
64BCR0.55498148
65NTRK30.55365410
66MAPKAPK50.55246794
67MAP3K120.53620266
68NLK0.52659667
69TAOK30.52490081
70SGK20.51925594
71CDK60.51683405
72ABL10.51124178
73CDK80.50492939
74PRKCE0.49082261
75OBSCN0.48367353
76OXSR10.48294089
77ZAP700.48094529
78BTK0.47582569
79HCK0.47422931
80EGFR0.47259290
81IGF1R0.46632468
82PRKCQ0.46608972
83PINK10.44977264
84ITK0.44546207
85INSRR0.44378590
86ADRBK20.43972263
87PRKCH0.43766774
88PDGFRA0.43678997
89ERBB30.42917953
90ROCK10.42768558
91LCK0.41389586
92GSK3A0.40653301
93CLK10.38724970
94IRAK10.38466070
95ROCK20.38091690
96GRK50.37684892
97TNIK0.36710287
98MAPK130.35826642
99DAPK20.35765666
100ADRBK10.35325759
101MAP3K30.34946490
102MKNK10.34190020
103PRKCD0.33828270
104PRKAA20.33425268
105MAP2K10.33397830
106PRKD10.32657387
107PIK3CA0.32632757
108CSNK1G10.32590796
109BMPR20.32180003
110SGK2230.31857342
111SGK4940.31857342
112EIF2AK20.31233586
113BLK0.30803280
114STK38L0.29769702
115PDPK10.29616628
116SRC0.29340655
117FLT30.28848843
118PRKG20.28571656
119WNK30.27774507
120CSF1R0.27669113
121LYN0.27626983
122ZAK0.27502703
123TAF10.26998285
124CAMK2A0.26715853
125PDK10.26692670
126FGFR20.26621328
127PIM20.26592254
128RPS6KA20.26214689
129FRK0.26121317
130PIM10.25776562
131STK30.25663355
132MAPK150.25647622
133JAK20.25617123
134MOS0.25369283
135CASK0.25071454
136PAK30.24700063
137TTN0.24534289
138RPS6KA40.24269596
139INSR0.23711222
140CAMK1D0.23121336
141PHKG20.20585876
142PHKG10.20585876
143PRKG10.19212010
144MARK10.18823615
145ABL20.16786789
146PLK20.16716292
147NTRK20.16629450
148CAMK40.16139743
149CAMKK20.15939949
150RET0.15794810

Predicted pathways (KEGG)

RankGene SetZ-score
1Malaria_Homo sapiens_hsa051442.46374993
2Leukocyte transendothelial migration_Homo sapiens_hsa046702.44589729
3RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.29102204
4Leishmaniasis_Homo sapiens_hsa051402.28892504
5alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.11402861
6Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.04642685
7Hematopoietic cell lineage_Homo sapiens_hsa046402.01275609
8Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.98175326
9Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.97727499
10NF-kappa B signaling pathway_Homo sapiens_hsa040641.97411892
11Viral myocarditis_Homo sapiens_hsa054161.96568865
12Staphylococcus aureus infection_Homo sapiens_hsa051501.93870728
13Linoleic acid metabolism_Homo sapiens_hsa005911.93207546
14Pertussis_Homo sapiens_hsa051331.92217694
15Complement and coagulation cascades_Homo sapiens_hsa046101.90746367
16ECM-receptor interaction_Homo sapiens_hsa045121.89338261
17Focal adhesion_Homo sapiens_hsa045101.88818388
18Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.78730669
19Adherens junction_Homo sapiens_hsa045201.73646256
20Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.72599267
21Toll-like receptor signaling pathway_Homo sapiens_hsa046201.71707873
22AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.71236030
23Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.70041637
24Measles_Homo sapiens_hsa051621.68686607
25Ether lipid metabolism_Homo sapiens_hsa005651.65173278
26Toxoplasmosis_Homo sapiens_hsa051451.61282232
27TNF signaling pathway_Homo sapiens_hsa046681.57135676
28Platelet activation_Homo sapiens_hsa046111.54737710
29Osteoclast differentiation_Homo sapiens_hsa043801.51799718
30Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.50875182
31Jak-STAT signaling pathway_Homo sapiens_hsa046301.50749048
32Salmonella infection_Homo sapiens_hsa051321.47031605
33Legionellosis_Homo sapiens_hsa051341.46561300
34Influenza A_Homo sapiens_hsa051641.45335321
35African trypanosomiasis_Homo sapiens_hsa051431.45089099
36Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.44267739
37Primary immunodeficiency_Homo sapiens_hsa053401.41681540
38Caffeine metabolism_Homo sapiens_hsa002321.38220089
39Allograft rejection_Homo sapiens_hsa053301.36249072
40Small cell lung cancer_Homo sapiens_hsa052221.34027882
41Rap1 signaling pathway_Homo sapiens_hsa040151.30265180
42Glutamatergic synapse_Homo sapiens_hsa047241.25267746
43Serotonergic synapse_Homo sapiens_hsa047261.25124795
44Rheumatoid arthritis_Homo sapiens_hsa053231.22294952
45Morphine addiction_Homo sapiens_hsa050321.20521611
46Graft-versus-host disease_Homo sapiens_hsa053321.19565915
47Intestinal immune network for IgA production_Homo sapiens_hsa046721.19352432
48B cell receptor signaling pathway_Homo sapiens_hsa046621.18534590
49Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.17053053
50Proteoglycans in cancer_Homo sapiens_hsa052051.16029737
51Selenocompound metabolism_Homo sapiens_hsa004501.14320169
52Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.13420691
53Nitrogen metabolism_Homo sapiens_hsa009101.12830789
54Hepatitis C_Homo sapiens_hsa051601.12112652
55Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.10751651
56Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.10286077
57TGF-beta signaling pathway_Homo sapiens_hsa043501.09055468
58Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.07404961
59Amoebiasis_Homo sapiens_hsa051461.07204813
60Sulfur metabolism_Homo sapiens_hsa009201.05229649
61NOD-like receptor signaling pathway_Homo sapiens_hsa046211.04862081
62Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.04342000
63Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.03163569
64Transcriptional misregulation in cancer_Homo sapiens_hsa052021.02828285
65Protein digestion and absorption_Homo sapiens_hsa049741.02807077
66Phagosome_Homo sapiens_hsa041451.02211987
67Circadian entrainment_Homo sapiens_hsa047131.01343014
68PI3K-Akt signaling pathway_Homo sapiens_hsa041511.00457865
69* Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.98012883
70Tuberculosis_Homo sapiens_hsa051520.97905356
71Shigellosis_Homo sapiens_hsa051310.97179581
72Dilated cardiomyopathy_Homo sapiens_hsa054140.96790846
73Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.95945924
74Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.95176831
75Regulation of actin cytoskeleton_Homo sapiens_hsa048100.94245107
76Herpes simplex infection_Homo sapiens_hsa051680.92498737
77Taste transduction_Homo sapiens_hsa047420.90174900
78Vitamin digestion and absorption_Homo sapiens_hsa049770.88874053
79Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.88444829
80Antigen processing and presentation_Homo sapiens_hsa046120.88272638
81Hepatitis B_Homo sapiens_hsa051610.87775377
82Chemokine signaling pathway_Homo sapiens_hsa040620.87440348
83Long-term depression_Homo sapiens_hsa047300.84532518
84Tryptophan metabolism_Homo sapiens_hsa003800.84315682
85cGMP-PKG signaling pathway_Homo sapiens_hsa040220.79893340
86cAMP signaling pathway_Homo sapiens_hsa040240.79350183
87Thyroid hormone synthesis_Homo sapiens_hsa049180.79223373
88Prostate cancer_Homo sapiens_hsa052150.77294838
89Apoptosis_Homo sapiens_hsa042100.77240466
90Oxytocin signaling pathway_Homo sapiens_hsa049210.76872394
91Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.76292211
92Salivary secretion_Homo sapiens_hsa049700.75179605
93Arachidonic acid metabolism_Homo sapiens_hsa005900.75165296
94PPAR signaling pathway_Homo sapiens_hsa033200.74991803
95Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.74894410
96Histidine metabolism_Homo sapiens_hsa003400.74801006
97Tight junction_Homo sapiens_hsa045300.74522180
98Pathways in cancer_Homo sapiens_hsa052000.74510549
99Gastric acid secretion_Homo sapiens_hsa049710.74210897
100GABAergic synapse_Homo sapiens_hsa047270.74018206
101Notch signaling pathway_Homo sapiens_hsa043300.72065867
102Arginine biosynthesis_Homo sapiens_hsa002200.70886903
103Prion diseases_Homo sapiens_hsa050200.70755125
104Sphingolipid metabolism_Homo sapiens_hsa006000.70665165
105HIF-1 signaling pathway_Homo sapiens_hsa040660.69685958
106Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.68862820
107SNARE interactions in vesicular transport_Homo sapiens_hsa041300.66573538
108Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.66174643
109Ras signaling pathway_Homo sapiens_hsa040140.65093897
110Bile secretion_Homo sapiens_hsa049760.64562052
111Adipocytokine signaling pathway_Homo sapiens_hsa049200.63727744
112Calcium signaling pathway_Homo sapiens_hsa040200.63047632
113* Vascular smooth muscle contraction_Homo sapiens_hsa042700.62684329
114Glycosaminoglycan degradation_Homo sapiens_hsa005310.62328067
115HTLV-I infection_Homo sapiens_hsa051660.61959750
116VEGF signaling pathway_Homo sapiens_hsa043700.61268503
117Pancreatic secretion_Homo sapiens_hsa049720.59714995
118Lysosome_Homo sapiens_hsa041420.57801277
119MicroRNAs in cancer_Homo sapiens_hsa052060.57698754
120Glycerophospholipid metabolism_Homo sapiens_hsa005640.56920323
121Glycerolipid metabolism_Homo sapiens_hsa005610.55624979
122Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.55161165
123Asthma_Homo sapiens_hsa053100.55044269
124Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.54021480
125Aldosterone synthesis and secretion_Homo sapiens_hsa049250.53993339
126Phototransduction_Homo sapiens_hsa047440.53124272
127Endocytosis_Homo sapiens_hsa041440.52765051
128Renin secretion_Homo sapiens_hsa049240.52612831
129Autoimmune thyroid disease_Homo sapiens_hsa053200.52528939
130Chemical carcinogenesis_Homo sapiens_hsa052040.52425806
131Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.51841237
132Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.51698158
133Cholinergic synapse_Homo sapiens_hsa047250.51164631
134Thyroid cancer_Homo sapiens_hsa052160.50975287
135Insulin secretion_Homo sapiens_hsa049110.50866250
136Insulin resistance_Homo sapiens_hsa049310.50394705
137Estrogen signaling pathway_Homo sapiens_hsa049150.50135067
138Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.48044961
139Propanoate metabolism_Homo sapiens_hsa006400.47544265
140MAPK signaling pathway_Homo sapiens_hsa040100.47310160
141Pancreatic cancer_Homo sapiens_hsa052120.46367229
142Hippo signaling pathway_Homo sapiens_hsa043900.46189107
143Other glycan degradation_Homo sapiens_hsa005110.45440003
144Butanoate metabolism_Homo sapiens_hsa006500.45307358
145Mineral absorption_Homo sapiens_hsa049780.43928751
146Basal cell carcinoma_Homo sapiens_hsa052170.43363034
147Circadian rhythm_Homo sapiens_hsa047100.43220357
148Ovarian steroidogenesis_Homo sapiens_hsa049130.41907660
149Axon guidance_Homo sapiens_hsa043600.41319437
150Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.41015701
151Renin-angiotensin system_Homo sapiens_hsa046140.40559263
152Phospholipase D signaling pathway_Homo sapiens_hsa040720.38923687
153Type I diabetes mellitus_Homo sapiens_hsa049400.38447167
154Dorso-ventral axis formation_Homo sapiens_hsa043200.38265594
155ABC transporters_Homo sapiens_hsa020100.36344231

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »