

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.88239964 |
| 2 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 5.56843233 |
| 3 | one-carbon compound transport (GO:0019755) | 5.44230968 |
| 4 | ATP synthesis coupled proton transport (GO:0015986) | 5.34091574 |
| 5 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.34091574 |
| 6 | aldehyde catabolic process (GO:0046185) | 5.24529800 |
| 7 | respiratory electron transport chain (GO:0022904) | 5.16246870 |
| 8 | electron transport chain (GO:0022900) | 5.10907506 |
| 9 | protein-cofactor linkage (GO:0018065) | 4.37099710 |
| 10 | proteasome assembly (GO:0043248) | 4.31449238 |
| 11 | respiratory chain complex IV assembly (GO:0008535) | 4.19700897 |
| 12 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.13736324 |
| 13 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.13736324 |
| 14 | protein neddylation (GO:0045116) | 4.10064238 |
| 15 | maturation of 5.8S rRNA (GO:0000460) | 4.10053111 |
| 16 | platelet dense granule organization (GO:0060155) | 4.07204213 |
| 17 | histone mRNA metabolic process (GO:0008334) | 4.00030031 |
| 18 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.93601795 |
| 19 | vascular smooth muscle contraction (GO:0014829) | 3.91863011 |
| 20 | protein complex biogenesis (GO:0070271) | 3.89817731 |
| 21 | hepatocyte apoptotic process (GO:0097284) | 3.80238359 |
| 22 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.79322434 |
| 23 | potassium ion homeostasis (GO:0055075) | 3.78860016 |
| 24 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.77590062 |
| 25 | artery smooth muscle contraction (GO:0014824) | 3.75794926 |
| 26 | short-term memory (GO:0007614) | 3.70374093 |
| 27 | chaperone-mediated protein transport (GO:0072321) | 3.63943023 |
| 28 | regulation of oxidative phosphorylation (GO:0002082) | 3.63219064 |
| 29 | cytochrome complex assembly (GO:0017004) | 3.60778154 |
| 30 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.54370501 |
| 31 | oxidative phosphorylation (GO:0006119) | 3.54191286 |
| 32 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.53543062 |
| 33 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.53543062 |
| 34 | NADH dehydrogenase complex assembly (GO:0010257) | 3.53543062 |
| 35 | maturation of SSU-rRNA (GO:0030490) | 3.49443400 |
| 36 | regulation of germinal center formation (GO:0002634) | 3.46637271 |
| 37 | base-excision repair, AP site formation (GO:0006285) | 3.43945278 |
| 38 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 3.34271257 |
| 39 | neural tube formation (GO:0001841) | 3.30257089 |
| 40 | hydrogen ion transmembrane transport (GO:1902600) | 3.29531065 |
| 41 | ATP biosynthetic process (GO:0006754) | 3.27002927 |
| 42 | tonic smooth muscle contraction (GO:0014820) | 3.23265322 |
| 43 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.22479520 |
| 44 | C-terminal protein lipidation (GO:0006501) | 3.20489295 |
| 45 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.19837931 |
| 46 | ribosomal large subunit biogenesis (GO:0042273) | 3.16246811 |
| 47 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class | 3.11777007 |
| 48 | DNA deamination (GO:0045006) | 3.09378315 |
| 49 | positive regulation of macrophage differentiation (GO:0045651) | 3.09297765 |
| 50 | hydrogen transport (GO:0006818) | 3.06710557 |
| 51 | proton transport (GO:0015992) | 3.05607534 |
| 52 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.01572342 |
| 53 | neutrophil activation involved in immune response (GO:0002283) | 3.00824566 |
| 54 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.98571160 |
| 55 | heme transport (GO:0015886) | 2.97595639 |
| 56 | C4-dicarboxylate transport (GO:0015740) | 2.94901868 |
| 57 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.93289411 |
| 58 | anterograde synaptic vesicle transport (GO:0048490) | 2.93176464 |
| 59 | regulation of triglyceride catabolic process (GO:0010896) | 2.91767107 |
| 60 | C-terminal protein amino acid modification (GO:0018410) | 2.91184048 |
| 61 | cullin deneddylation (GO:0010388) | 2.88264422 |
| 62 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.85805081 |
| 63 | regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902108) | 2.82576905 |
| 64 | establishment of integrated proviral latency (GO:0075713) | 2.82274665 |
| 65 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 2.75991975 |
| 66 | regulation of sister chromatid cohesion (GO:0007063) | 2.73115729 |
| 67 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.72073225 |
| 68 | tryptophan metabolic process (GO:0006568) | 2.71280253 |
| 69 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.69585880 |
| 70 | nucleoside triphosphate biosynthetic process (GO:0009142) | 2.69261468 |
| 71 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.69245061 |
| 72 | negative regulation of ligase activity (GO:0051352) | 2.69245061 |
| 73 | positive regulation of ligase activity (GO:0051351) | 2.67764965 |
| 74 | purine deoxyribonucleotide catabolic process (GO:0009155) | 2.66588907 |
| 75 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.66265326 |
| 76 | mismatch repair (GO:0006298) | 2.65671503 |
| 77 | protein prenylation (GO:0018342) | 2.65089074 |
| 78 | prenylation (GO:0097354) | 2.65089074 |
| 79 | positive regulation of cardiac muscle hypertrophy (GO:0010613) | 2.64330036 |
| 80 | positive regulation of muscle hypertrophy (GO:0014742) | 2.64330036 |
| 81 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.64283837 |
| 82 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.63512637 |
| 83 | spliceosomal complex assembly (GO:0000245) | 2.60156222 |
| 84 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.59252099 |
| 85 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.58751444 |
| 86 | adenosine metabolic process (GO:0046085) | 2.58335864 |
| 87 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.58137920 |
| 88 | RNA phosphodiester bond hydrolysis (GO:0090501) | 2.58064642 |
| 89 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.57723241 |
| 90 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.57723241 |
| 91 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.57723241 |
| 92 | response to nitrosative stress (GO:0051409) | 2.56697183 |
| 93 | histone mRNA catabolic process (GO:0071044) | 2.56681162 |
| 94 | protein targeting to mitochondrion (GO:0006626) | 2.53556930 |
| 95 | translation (GO:0006412) | 2.53220325 |
| 96 | innate immune response in mucosa (GO:0002227) | 2.52599494 |
| 97 | auditory receptor cell stereocilium organization (GO:0060088) | 2.52483681 |
| 98 | indolalkylamine metabolic process (GO:0006586) | 2.51973729 |
| 99 | regulation of lipopolysaccharide-mediated signaling pathway (GO:0031664) | 2.51028178 |
| 100 | gonadal mesoderm development (GO:0007506) | 10.3541916 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.17116720 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.66915960 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.53832000 |
| 4 | TAF15_26573619_Chip-Seq_HEK293_Human | 3.13896717 |
| 5 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 3.01096878 |
| 6 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.70454556 |
| 7 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.61866318 |
| 8 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.48599224 |
| 9 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.45938825 |
| 10 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.41912954 |
| 11 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.40851950 |
| 12 | VDR_22108803_ChIP-Seq_LS180_Human | 2.31932809 |
| 13 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.21937866 |
| 14 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 2.16405775 |
| 15 | FUS_26573619_Chip-Seq_HEK293_Human | 2.14832948 |
| 16 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.12536566 |
| 17 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.10336549 |
| 18 | EWS_26573619_Chip-Seq_HEK293_Human | 2.03659544 |
| 19 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.97459686 |
| 20 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.96586349 |
| 21 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.96352212 |
| 22 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.94532892 |
| 23 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.91889413 |
| 24 | P300_19829295_ChIP-Seq_ESCs_Human | 1.87736440 |
| 25 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.87188216 |
| 26 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.84642169 |
| 27 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.79923485 |
| 28 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.79720967 |
| 29 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.79450296 |
| 30 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.78304260 |
| 31 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.75384763 |
| 32 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.71013239 |
| 33 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.71013239 |
| 34 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.66550746 |
| 35 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.65768811 |
| 36 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.61374314 |
| 37 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.59780959 |
| 38 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.57294506 |
| 39 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.56650548 |
| 40 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.49652583 |
| 41 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.45252843 |
| 42 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.43832219 |
| 43 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.43701476 |
| 44 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.43612567 |
| 45 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.42550594 |
| 46 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.40675809 |
| 47 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.40219319 |
| 48 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.39730587 |
| 49 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.39182956 |
| 50 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.38055263 |
| 51 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.37937560 |
| 52 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.31452469 |
| 53 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.29384134 |
| 54 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.29052299 |
| 55 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.27902423 |
| 56 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.25506872 |
| 57 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.24713913 |
| 58 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.24583073 |
| 59 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.23390294 |
| 60 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.22182408 |
| 61 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.22182408 |
| 62 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.21399642 |
| 63 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.21386469 |
| 64 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.20727173 |
| 65 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.20727173 |
| 66 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.19212266 |
| 67 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.17924428 |
| 68 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.17204332 |
| 69 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.16631871 |
| 70 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.14036338 |
| 71 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.13981825 |
| 72 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.11360130 |
| 73 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.09995851 |
| 74 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.09626041 |
| 75 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.09392957 |
| 76 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.07651404 |
| 77 | AR_20517297_ChIP-Seq_VCAP_Human | 1.06473492 |
| 78 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.05819233 |
| 79 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.04628034 |
| 80 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.03891228 |
| 81 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.03817464 |
| 82 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.03740531 |
| 83 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.03704276 |
| 84 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 1.03124013 |
| 85 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.03094709 |
| 86 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.02085007 |
| 87 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.00966265 |
| 88 | JUN_21703547_ChIP-Seq_K562_Human | 1.00704584 |
| 89 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.99937160 |
| 90 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.99512395 |
| 91 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.98962842 |
| 92 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.98880137 |
| 93 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 0.98513474 |
| 94 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.98311603 |
| 95 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.97537550 |
| 96 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 0.97451882 |
| 97 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.96729022 |
| 98 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.96424979 |
| 99 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.96036301 |
| 100 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.96036301 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003806_abnormal_nucleotide_metabolis | 6.21260571 |
| 2 | MP0000372_irregular_coat_pigmentation | 4.80256803 |
| 3 | MP0004147_increased_porphyrin_level | 4.18258135 |
| 4 | MP0000516_abnormal_urinary_system | 3.88183831 |
| 5 | MP0005367_renal/urinary_system_phenotyp | 3.88183831 |
| 6 | MP0008057_abnormal_DNA_replication | 3.30659723 |
| 7 | MP0008877_abnormal_DNA_methylation | 3.17480804 |
| 8 | MP0006054_spinal_hemorrhage | 2.75097416 |
| 9 | MP0008875_abnormal_xenobiotic_pharmacok | 2.42007273 |
| 10 | MP0008872_abnormal_physiological_respon | 2.40643434 |
| 11 | MP0005408_hypopigmentation | 2.36996443 |
| 12 | MP0002837_dystrophic_cardiac_calcinosis | 2.27144866 |
| 13 | MP0006036_abnormal_mitochondrial_physio | 2.12941704 |
| 14 | MP0003195_calcinosis | 2.11985331 |
| 15 | MP0009764_decreased_sensitivity_to | 2.03645746 |
| 16 | MP0005075_abnormal_melanosome_morpholog | 2.02970756 |
| 17 | MP0009379_abnormal_foot_pigmentation | 1.90930626 |
| 18 | MP0005671_abnormal_response_to | 1.82632385 |
| 19 | MP0005085_abnormal_gallbladder_physiolo | 1.81107658 |
| 20 | MP0009697_abnormal_copulation | 1.79224781 |
| 21 | MP0004215_abnormal_myocardial_fiber | 1.71381886 |
| 22 | MP0004742_abnormal_vestibular_system | 1.69506678 |
| 23 | MP0002163_abnormal_gland_morphology | 1.65967145 |
| 24 | MP0003252_abnormal_bile_duct | 1.62579416 |
| 25 | MP0002396_abnormal_hematopoietic_system | 1.60142585 |
| 26 | MP0001727_abnormal_embryo_implantation | 1.59934623 |
| 27 | MP0006072_abnormal_retinal_apoptosis | 1.56832249 |
| 28 | MP0009046_muscle_twitch | 1.55692993 |
| 29 | MP0002234_abnormal_pharynx_morphology | 1.55362406 |
| 30 | MP0002938_white_spotting | 1.53206541 |
| 31 | MP0005551_abnormal_eye_electrophysiolog | 1.50593860 |
| 32 | MP0001486_abnormal_startle_reflex | 1.46133927 |
| 33 | MP0001529_abnormal_vocalization | 1.45903925 |
| 34 | MP0001984_abnormal_olfaction | 1.43015698 |
| 35 | MP0005266_abnormal_metabolism | 1.42320067 |
| 36 | MP0002736_abnormal_nociception_after | 1.41583028 |
| 37 | MP0008995_early_reproductive_senescence | 1.38275948 |
| 38 | MP0001501_abnormal_sleep_pattern | 1.32091637 |
| 39 | MP0006035_abnormal_mitochondrial_morpho | 1.30006553 |
| 40 | MP0004019_abnormal_vitamin_homeostasis | 1.28525498 |
| 41 | MP0005646_abnormal_pituitary_gland | 1.26965660 |
| 42 | MP0001835_abnormal_antigen_presentation | 1.24674116 |
| 43 | MP0005379_endocrine/exocrine_gland_phen | 1.23048706 |
| 44 | MP0002102_abnormal_ear_morphology | 1.20052788 |
| 45 | MP0002272_abnormal_nervous_system | 1.19806664 |
| 46 | MP0001485_abnormal_pinna_reflex | 1.15763038 |
| 47 | MP0010386_abnormal_urinary_bladder | 1.10229851 |
| 48 | MP0003011_delayed_dark_adaptation | 1.09997329 |
| 49 | MP0003137_abnormal_impulse_conducting | 1.09564111 |
| 50 | MP0003880_abnormal_central_pattern | 1.08654371 |
| 51 | MP0001968_abnormal_touch/_nociception | 1.08005318 |
| 52 | MP0002148_abnormal_hypersensitivity_rea | 0.98215643 |
| 53 | MP0002160_abnormal_reproductive_system | 0.97185031 |
| 54 | MP0001756_abnormal_urination | 0.96494328 |
| 55 | MP0002006_tumorigenesis | 0.95667542 |
| 56 | MP0002734_abnormal_mechanical_nocicepti | 0.95628103 |
| 57 | MP0003638_abnormal_response/metabolism_ | 0.94639740 |
| 58 | MP0008058_abnormal_DNA_repair | 0.93784584 |
| 59 | MP0002254_reproductive_system_inflammat | 0.93783616 |
| 60 | MP0004142_abnormal_muscle_tone | 0.93299695 |
| 61 | MP0003890_abnormal_embryonic-extraembry | 0.92491815 |
| 62 | MP0003787_abnormal_imprinting | 0.91769740 |
| 63 | MP0002751_abnormal_autonomic_nervous | 0.88789531 |
| 64 | MP0001970_abnormal_pain_threshold | 0.88628779 |
| 65 | MP0005174_abnormal_tail_pigmentation | 0.88370284 |
| 66 | MP0009785_altered_susceptibility_to | 0.87079747 |
| 67 | MP0005166_decreased_susceptibility_to | 0.86580851 |
| 68 | MP0001440_abnormal_grooming_behavior | 0.84326317 |
| 69 | MP0000534_abnormal_ureter_morphology | 0.83370149 |
| 70 | MP0002090_abnormal_vision | 0.82966927 |
| 71 | MP0001764_abnormal_homeostasis | 0.81491974 |
| 72 | MP0005410_abnormal_fertilization | 0.81313707 |
| 73 | MP0005253_abnormal_eye_physiology | 0.78487662 |
| 74 | MP0005332_abnormal_amino_acid | 0.78367764 |
| 75 | MP0003718_maternal_effect | 0.77281944 |
| 76 | MP0005389_reproductive_system_phenotype | 0.76088874 |
| 77 | MP0000685_abnormal_immune_system | 0.74790143 |
| 78 | MP0006292_abnormal_olfactory_placode | 0.74133063 |
| 79 | MP0003646_muscle_fatigue | 0.73762416 |
| 80 | MP0005084_abnormal_gallbladder_morpholo | 0.72993379 |
| 81 | MP0003693_abnormal_embryo_hatching | 0.72614998 |
| 82 | MP0005645_abnormal_hypothalamus_physiol | 0.72011526 |
| 83 | MP0003136_yellow_coat_color | 0.70521597 |
| 84 | MP0002928_abnormal_bile_duct | 0.69881669 |
| 85 | MP0008775_abnormal_heart_ventricle | 0.69630483 |
| 86 | MP0006276_abnormal_autonomic_nervous | 0.68471164 |
| 87 | MP0005360_urolithiasis | 0.67840427 |
| 88 | MP0005636_abnormal_mineral_homeostasis | 0.67388147 |
| 89 | MP0003567_abnormal_fetal_cardiomyocyte | 0.66811817 |
| 90 | MP0000639_abnormal_adrenal_gland | 0.64927208 |
| 91 | MP0000647_abnormal_sebaceous_gland | 0.64329291 |
| 92 | MP0009745_abnormal_behavioral_response | 0.62111429 |
| 93 | MP0005535_abnormal_body_temperature | 0.61585557 |
| 94 | MP0004484_altered_response_of | 0.60596764 |
| 95 | MP0008873_increased_physiological_sensi | 0.60575141 |
| 96 | MP0005365_abnormal_bile_salt | 0.60281471 |
| 97 | MP0001542_abnormal_bone_strength | 0.58127850 |
| 98 | MP0004084_abnormal_cardiac_muscle | 0.57852784 |
| 99 | MP0001905_abnormal_dopamine_level | 0.56960423 |
| 100 | MP0010094_abnormal_chromosome_stability | 0.56852449 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 6.48080798 |
| 2 | Mitochondrial inheritance (HP:0001427) | 5.97164066 |
| 3 | Hepatocellular necrosis (HP:0001404) | 5.85799086 |
| 4 | Acute encephalopathy (HP:0006846) | 5.75696771 |
| 5 | Abnormal mitochondria in muscle tissue (HP:0008316) | 5.63758075 |
| 6 | Progressive macrocephaly (HP:0004481) | 5.53181262 |
| 7 | Increased CSF lactate (HP:0002490) | 5.43545641 |
| 8 | Hepatic necrosis (HP:0002605) | 5.09708907 |
| 9 | Congenital, generalized hypertrichosis (HP:0004540) | 5.07614503 |
| 10 | Cerebral edema (HP:0002181) | 4.21282676 |
| 11 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 4.13142819 |
| 12 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 4.13142819 |
| 13 | Increased hepatocellular lipid droplets (HP:0006565) | 3.83849167 |
| 14 | Leukodystrophy (HP:0002415) | 3.72705272 |
| 15 | Type I transferrin isoform profile (HP:0003642) | 3.68854880 |
| 16 | Hypothermia (HP:0002045) | 3.67626548 |
| 17 | Lipid accumulation in hepatocytes (HP:0006561) | 3.66952962 |
| 18 | Respiratory failure (HP:0002878) | 3.56882717 |
| 19 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.41775050 |
| 20 | 3-Methylglutaconic aciduria (HP:0003535) | 3.27421493 |
| 21 | Lactic acidosis (HP:0003128) | 3.23594511 |
| 22 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 3.17014912 |
| 23 | Optic disc pallor (HP:0000543) | 3.12106035 |
| 24 | Increased serum lactate (HP:0002151) | 3.10531829 |
| 25 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 3.09901019 |
| 26 | Increased intramyocellular lipid droplets (HP:0012240) | 2.92000095 |
| 27 | Woolly hair (HP:0002224) | 2.75152991 |
| 28 | Progressive microcephaly (HP:0000253) | 2.73766954 |
| 29 | Sensory axonal neuropathy (HP:0003390) | 2.72244610 |
| 30 | Amniotic constriction ring (HP:0009775) | 2.72039110 |
| 31 | Abnormality of placental membranes (HP:0011409) | 2.72039110 |
| 32 | X-linked dominant inheritance (HP:0001423) | 2.71623358 |
| 33 | CNS demyelination (HP:0007305) | 2.68621168 |
| 34 | Exercise intolerance (HP:0003546) | 2.62783605 |
| 35 | Exertional dyspnea (HP:0002875) | 2.60009762 |
| 36 | Myokymia (HP:0002411) | 2.53060527 |
| 37 | Increased muscle lipid content (HP:0009058) | 2.48953375 |
| 38 | Abnormality of renal resorption (HP:0011038) | 2.47975861 |
| 39 | Renal Fanconi syndrome (HP:0001994) | 2.46999697 |
| 40 | Chronic diarrhea (HP:0002028) | 2.39375059 |
| 41 | Congenital ichthyosiform erythroderma (HP:0007431) | 2.36852046 |
| 42 | Abnormal protein glycosylation (HP:0012346) | 2.36053473 |
| 43 | Abnormal glycosylation (HP:0012345) | 2.36053473 |
| 44 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.36053473 |
| 45 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.36053473 |
| 46 | Emotional lability (HP:0000712) | 2.28010421 |
| 47 | Delayed CNS myelination (HP:0002188) | 2.21633564 |
| 48 | Reduced antithrombin III activity (HP:0001976) | 2.17463896 |
| 49 | Lethargy (HP:0001254) | 2.16847479 |
| 50 | Palpitations (HP:0001962) | 2.11875254 |
| 51 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.10732019 |
| 52 | Facial diplegia (HP:0001349) | 2.08221002 |
| 53 | Aplasia cutis congenita (HP:0001057) | 2.07876409 |
| 54 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.06948370 |
| 55 | Glycosuria (HP:0003076) | 2.06259732 |
| 56 | Abnormality of urine glucose concentration (HP:0011016) | 2.06259732 |
| 57 | Febrile seizures (HP:0002373) | 2.06198111 |
| 58 | Respiratory difficulties (HP:0002880) | 2.04807228 |
| 59 | Abnormality of abdominal situs (HP:0011620) | 2.03831841 |
| 60 | Abdominal situs inversus (HP:0003363) | 2.03831841 |
| 61 | Delayed gross motor development (HP:0002194) | 1.97009330 |
| 62 | Dry hair (HP:0011359) | 1.96393308 |
| 63 | Medial flaring of the eyebrow (HP:0010747) | 1.90384480 |
| 64 | Blindness (HP:0000618) | 1.89097096 |
| 65 | Intestinal atresia (HP:0011100) | 1.84748076 |
| 66 | Abnormality of alanine metabolism (HP:0010916) | 1.81692439 |
| 67 | Hyperalaninemia (HP:0003348) | 1.81692439 |
| 68 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.81692439 |
| 69 | Tetany (HP:0001281) | 1.81335352 |
| 70 | Delayed myelination (HP:0012448) | 1.80983394 |
| 71 | Limb dystonia (HP:0002451) | 1.80146572 |
| 72 | Atonic seizures (HP:0010819) | 1.78782261 |
| 73 | Hypoproteinemia (HP:0003075) | 1.78326972 |
| 74 | Nausea (HP:0002018) | 1.77742959 |
| 75 | Petechiae (HP:0000967) | 1.76259193 |
| 76 | Poor suck (HP:0002033) | 1.71224115 |
| 77 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.71029462 |
| 78 | Spastic paraparesis (HP:0002313) | 1.70508772 |
| 79 | Sclerocornea (HP:0000647) | 1.70021047 |
| 80 | Reticulocytopenia (HP:0001896) | 1.69996004 |
| 81 | Decreased central vision (HP:0007663) | 1.68956538 |
| 82 | Hypomagnesemia (HP:0002917) | 1.68831111 |
| 83 | Congenital stationary night blindness (HP:0007642) | 1.68684716 |
| 84 | Abnormality of T cell physiology (HP:0011840) | 1.68547989 |
| 85 | Adrenal hypoplasia (HP:0000835) | 1.68457429 |
| 86 | Male pseudohermaphroditism (HP:0000037) | 1.68185433 |
| 87 | Increased corneal curvature (HP:0100692) | 1.67676976 |
| 88 | Keratoconus (HP:0000563) | 1.67676976 |
| 89 | Small hand (HP:0200055) | 1.66786922 |
| 90 | Poor speech (HP:0002465) | 1.65872519 |
| 91 | Porencephaly (HP:0002132) | 1.64041215 |
| 92 | Pancreatic cysts (HP:0001737) | 1.63564344 |
| 93 | Absent hand (HP:0004050) | 1.62907554 |
| 94 | Vomiting (HP:0002013) | 1.62656805 |
| 95 | Renal tubular dysfunction (HP:0000124) | 1.62467716 |
| 96 | Micronodular cirrhosis (HP:0001413) | 1.62284014 |
| 97 | Intellectual disability, profound (HP:0002187) | 1.61552057 |
| 98 | Abnormality of magnesium homeostasis (HP:0004921) | 1.61406769 |
| 99 | Poor head control (HP:0002421) | 1.60754052 |
| 100 | Abolished electroretinogram (ERG) (HP:0000550) | 1.59369141 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP3K12 | 5.62134295 |
| 2 | ZAK | 2.86370257 |
| 3 | MYLK | 2.82389538 |
| 4 | BMPR1B | 2.67213225 |
| 5 | FRK | 2.36968887 |
| 6 | TSSK6 | 2.31248890 |
| 7 | MST4 | 2.11333370 |
| 8 | VRK2 | 2.02923332 |
| 9 | WNK3 | 2.00617001 |
| 10 | BMPR2 | 1.95247463 |
| 11 | STK16 | 1.90045082 |
| 12 | PLK4 | 1.87039790 |
| 13 | NUAK1 | 1.86673109 |
| 14 | ILK | 1.85929510 |
| 15 | MAPKAPK3 | 1.81713095 |
| 16 | EIF2AK3 | 1.67683958 |
| 17 | TIE1 | 1.62281822 |
| 18 | CDK8 | 1.62192808 |
| 19 | EIF2AK1 | 1.60926877 |
| 20 | STK38L | 1.60789969 |
| 21 | ACVR1B | 1.56098998 |
| 22 | DAPK1 | 1.55351289 |
| 23 | OXSR1 | 1.52946830 |
| 24 | TAOK3 | 1.45523498 |
| 25 | ADRBK2 | 1.39331741 |
| 26 | MAPK13 | 1.36273304 |
| 27 | GRK1 | 1.28364770 |
| 28 | MKNK2 | 1.27404569 |
| 29 | PLK3 | 1.26818652 |
| 30 | TEC | 1.26290423 |
| 31 | STK39 | 1.20367768 |
| 32 | CSNK1G2 | 1.19981639 |
| 33 | NEK1 | 1.16893213 |
| 34 | MAP4K2 | 1.15098728 |
| 35 | MAP3K4 | 1.14883547 |
| 36 | CSNK1G3 | 1.13087950 |
| 37 | ROCK1 | 1.10845953 |
| 38 | SRPK1 | 1.06599078 |
| 39 | CASK | 1.03444576 |
| 40 | INSRR | 1.02036453 |
| 41 | STK24 | 1.01827365 |
| 42 | PAK4 | 0.99593513 |
| 43 | CCNB1 | 0.98217859 |
| 44 | ERBB3 | 0.97895434 |
| 45 | DAPK3 | 0.97706727 |
| 46 | TRIM28 | 0.91051174 |
| 47 | CSNK1G1 | 0.89973192 |
| 48 | TNIK | 0.89735228 |
| 49 | CSNK1A1L | 0.88661776 |
| 50 | DYRK3 | 0.87363278 |
| 51 | CDK19 | 0.87054400 |
| 52 | WNK4 | 0.86749747 |
| 53 | TGFBR1 | 0.86468997 |
| 54 | PDK2 | 0.84658017 |
| 55 | PLK2 | 0.83038459 |
| 56 | PAK3 | 0.80783937 |
| 57 | TAF1 | 0.77978520 |
| 58 | CDK3 | 0.70903889 |
| 59 | ROCK2 | 0.70247333 |
| 60 | MAP2K7 | 0.65424525 |
| 61 | PRKCG | 0.64865957 |
| 62 | IKBKB | 0.63124876 |
| 63 | DMPK | 0.60150208 |
| 64 | VRK1 | 0.60049523 |
| 65 | PKN1 | 0.59456684 |
| 66 | ADRBK1 | 0.58972477 |
| 67 | BUB1 | 0.58713949 |
| 68 | EIF2AK2 | 0.57935384 |
| 69 | CAMK2A | 0.56236618 |
| 70 | MKNK1 | 0.55509538 |
| 71 | PLK1 | 0.55129753 |
| 72 | PRKCA | 0.54497526 |
| 73 | STK10 | 0.54304696 |
| 74 | CSNK2A2 | 0.53796310 |
| 75 | CSNK2A1 | 0.52170951 |
| 76 | PRKCE | 0.51650488 |
| 77 | ATR | 0.50759150 |
| 78 | PIM1 | 0.49968299 |
| 79 | PBK | 0.49956326 |
| 80 | PHKG2 | 0.49819221 |
| 81 | PHKG1 | 0.49819221 |
| 82 | ITK | 0.49555399 |
| 83 | CAMK2D | 0.49206830 |
| 84 | IGF1R | 0.48733040 |
| 85 | ALK | 0.47320379 |
| 86 | GRK5 | 0.46903517 |
| 87 | AKT3 | 0.46847754 |
| 88 | MAP4K1 | 0.46271171 |
| 89 | LYN | 0.44735017 |
| 90 | OBSCN | 0.44622565 |
| 91 | MUSK | 0.44233117 |
| 92 | DAPK2 | 0.43690999 |
| 93 | PRKG1 | 0.42920049 |
| 94 | CAMK2G | 0.41797491 |
| 95 | STK3 | 0.41503056 |
| 96 | WEE1 | 0.40359800 |
| 97 | KIT | 0.39931467 |
| 98 | PRKACA | 0.38740565 |
| 99 | PINK1 | 0.37971766 |
| 100 | CSNK1E | 0.37801473 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.78438309 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 3.70265296 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.64328111 |
| 4 | Protein export_Homo sapiens_hsa03060 | 2.96978505 |
| 5 | Alzheimers disease_Homo sapiens_hsa05010 | 2.89081163 |
| 6 | Huntingtons disease_Homo sapiens_hsa05016 | 2.64551561 |
| 7 | Ribosome_Homo sapiens_hsa03010 | 2.62964185 |
| 8 | Sulfur metabolism_Homo sapiens_hsa00920 | 2.56947132 |
| 9 | Asthma_Homo sapiens_hsa05310 | 2.55080321 |
| 10 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.52089548 |
| 11 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.51673318 |
| 12 | Homologous recombination_Homo sapiens_hsa03440 | 2.16266650 |
| 13 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.14850464 |
| 14 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.13603924 |
| 15 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.94802234 |
| 16 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.90691094 |
| 17 | Allograft rejection_Homo sapiens_hsa05330 | 1.78791171 |
| 18 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.70804056 |
| 19 | RNA degradation_Homo sapiens_hsa03018 | 1.69560265 |
| 20 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.69381678 |
| 21 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.68175600 |
| 22 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.65868887 |
| 23 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.58330522 |
| 24 | Basal transcription factors_Homo sapiens_hsa03022 | 1.43816237 |
| 25 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.40030536 |
| 26 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.38450100 |
| 27 | DNA replication_Homo sapiens_hsa03030 | 1.35585892 |
| 28 | Mismatch repair_Homo sapiens_hsa03430 | 1.19013009 |
| 29 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.10980880 |
| 30 | Base excision repair_Homo sapiens_hsa03410 | 1.10064524 |
| 31 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.08024768 |
| 32 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.05962567 |
| 33 | Viral myocarditis_Homo sapiens_hsa05416 | 1.05039547 |
| 34 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.01489752 |
| 35 | RNA polymerase_Homo sapiens_hsa03020 | 1.00778801 |
| 36 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.97754259 |
| 37 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.95198671 |
| 38 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.94783231 |
| 39 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.94577106 |
| 40 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.93972665 |
| 41 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.89954413 |
| 42 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.89696553 |
| 43 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.88051341 |
| 44 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.83178671 |
| 45 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.80514912 |
| 46 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.79065303 |
| 47 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.77182590 |
| 48 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.77046962 |
| 49 | RNA transport_Homo sapiens_hsa03013 | 0.76186709 |
| 50 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.74111291 |
| 51 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.71720965 |
| 52 | Phototransduction_Homo sapiens_hsa04744 | 0.71138084 |
| 53 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.68774094 |
| 54 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.68234198 |
| 55 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.66237537 |
| 56 | Spliceosome_Homo sapiens_hsa03040 | 0.64539518 |
| 57 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.64467594 |
| 58 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.64390611 |
| 59 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.63843200 |
| 60 | GABAergic synapse_Homo sapiens_hsa04727 | 0.63629330 |
| 61 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.63532224 |
| 62 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.63489037 |
| 63 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.63101958 |
| 64 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.62991744 |
| 65 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.62429610 |
| 66 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.62121714 |
| 67 | Nicotine addiction_Homo sapiens_hsa05033 | 0.61987219 |
| 68 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.60514704 |
| 69 | Metabolic pathways_Homo sapiens_hsa01100 | 0.58908370 |
| 70 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.56418434 |
| 71 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.54800133 |
| 72 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.54745033 |
| 73 | Purine metabolism_Homo sapiens_hsa00230 | 0.49856561 |
| 74 | Morphine addiction_Homo sapiens_hsa05032 | 0.47144222 |
| 75 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.46782570 |
| 76 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.45538133 |
| 77 | Taste transduction_Homo sapiens_hsa04742 | 0.45473132 |
| 78 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.44982829 |
| 79 | Retinol metabolism_Homo sapiens_hsa00830 | 0.44761767 |
| 80 | Legionellosis_Homo sapiens_hsa05134 | 0.43085794 |
| 81 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.42568797 |
| 82 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.41328656 |
| 83 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.37530884 |
| 84 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.37411970 |
| 85 | Mineral absorption_Homo sapiens_hsa04978 | 0.35264943 |
| 86 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.35220710 |
| 87 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.34280883 |
| 88 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.33476699 |
| 89 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.31035733 |
| 90 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.30833110 |
| 91 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.29294244 |
| 92 | Olfactory transduction_Homo sapiens_hsa04740 | 0.28744926 |
| 93 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.28421722 |
| 94 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.28297173 |
| 95 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.26795025 |
| 96 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.23627130 |
| 97 | Circadian entrainment_Homo sapiens_hsa04713 | 0.22907086 |
| 98 | Phagosome_Homo sapiens_hsa04145 | 0.21991927 |
| 99 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.20625019 |
| 100 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.19937884 |

