

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA double-strand break processing (GO:0000729) | 7.28443459 |
| 2 | cytochrome complex assembly (GO:0017004) | 5.54109670 |
| 3 | respiratory chain complex IV assembly (GO:0008535) | 5.25566062 |
| 4 | indolalkylamine catabolic process (GO:0046218) | 5.24394204 |
| 5 | tryptophan catabolic process (GO:0006569) | 5.24394204 |
| 6 | indole-containing compound catabolic process (GO:0042436) | 5.24394204 |
| 7 | kynurenine metabolic process (GO:0070189) | 4.93265045 |
| 8 | DNA catabolic process, exonucleolytic (GO:0000738) | 4.73080274 |
| 9 | maturation of 5.8S rRNA (GO:0000460) | 4.69578949 |
| 10 | mitochondrial DNA replication (GO:0006264) | 4.40285992 |
| 11 | protein complex biogenesis (GO:0070271) | 4.37162119 |
| 12 | tryptophan metabolic process (GO:0006568) | 4.29272875 |
| 13 | DNA deamination (GO:0045006) | 4.25494005 |
| 14 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.01295605 |
| 15 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.96941243 |
| 16 | behavioral response to nicotine (GO:0035095) | 3.95351159 |
| 17 | dopamine transport (GO:0015872) | 3.89529632 |
| 18 | aromatic amino acid family catabolic process (GO:0009074) | 3.85077093 |
| 19 | ATP synthesis coupled proton transport (GO:0015986) | 3.79518606 |
| 20 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.79518606 |
| 21 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.79111510 |
| 22 | indolalkylamine metabolic process (GO:0006586) | 3.77284606 |
| 23 | heart contraction (GO:0060047) | 3.75717925 |
| 24 | heart process (GO:0003015) | 3.75717925 |
| 25 | DNA replication checkpoint (GO:0000076) | 3.72419431 |
| 26 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.66543236 |
| 27 | L-fucose catabolic process (GO:0042355) | 3.60665202 |
| 28 | fucose catabolic process (GO:0019317) | 3.60665202 |
| 29 | L-fucose metabolic process (GO:0042354) | 3.60665202 |
| 30 | amine catabolic process (GO:0009310) | 3.56619870 |
| 31 | cellular biogenic amine catabolic process (GO:0042402) | 3.56619870 |
| 32 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.53048339 |
| 33 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.48943003 |
| 34 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.46162490 |
| 35 | proteasome assembly (GO:0043248) | 3.45625257 |
| 36 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.44583035 |
| 37 | neuronal action potential propagation (GO:0019227) | 3.37912819 |
| 38 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.32489401 |
| 39 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.32489401 |
| 40 | NADH dehydrogenase complex assembly (GO:0010257) | 3.32489401 |
| 41 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 3.27307578 |
| 42 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.24719209 |
| 43 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.24719209 |
| 44 | autophagic vacuole fusion (GO:0000046) | 3.24509600 |
| 45 | GMP metabolic process (GO:0046037) | 3.23329281 |
| 46 | chaperone-mediated protein transport (GO:0072321) | 3.18633983 |
| 47 | piRNA metabolic process (GO:0034587) | 3.14279332 |
| 48 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.11918819 |
| 49 | regulation of mitochondrial translation (GO:0070129) | 3.11153533 |
| 50 | inositol phosphate catabolic process (GO:0071545) | 3.08689122 |
| 51 | phosphorylated carbohydrate dephosphorylation (GO:0046838) | 3.05465489 |
| 52 | inositol phosphate dephosphorylation (GO:0046855) | 3.05465489 |
| 53 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.02924917 |
| 54 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.02924917 |
| 55 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.02924917 |
| 56 | electron transport chain (GO:0022900) | 3.02025209 |
| 57 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.00339783 |
| 58 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.00339783 |
| 59 | respiratory electron transport chain (GO:0022904) | 2.99705238 |
| 60 | replication fork processing (GO:0031297) | 2.97912050 |
| 61 | regulation of glucokinase activity (GO:0033131) | 2.97574406 |
| 62 | regulation of hexokinase activity (GO:1903299) | 2.97574406 |
| 63 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.96979744 |
| 64 | postreplication repair (GO:0006301) | 2.96252849 |
| 65 | response to misfolded protein (GO:0051788) | 2.93601283 |
| 66 | NAD biosynthetic process (GO:0009435) | 2.85050556 |
| 67 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.83530051 |
| 68 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.81913165 |
| 69 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.81913165 |
| 70 | oxidative phosphorylation (GO:0006119) | 2.81318343 |
| 71 | protein K6-linked ubiquitination (GO:0085020) | 2.78919954 |
| 72 | negative regulation of telomere maintenance (GO:0032205) | 2.78645246 |
| 73 | adenosine metabolic process (GO:0046085) | 2.77192780 |
| 74 | purine nucleotide salvage (GO:0032261) | 2.76874835 |
| 75 | negative regulation of T cell differentiation in thymus (GO:0033085) | 2.73524022 |
| 76 | nucleotide transmembrane transport (GO:1901679) | 2.72033338 |
| 77 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.71389191 |
| 78 | termination of RNA polymerase III transcription (GO:0006386) | 2.71389191 |
| 79 | regulation of ER to Golgi vesicle-mediated transport (GO:0060628) | 2.70642662 |
| 80 | aromatic amino acid family metabolic process (GO:0009072) | 2.70055394 |
| 81 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.66711407 |
| 82 | DNA-dependent DNA replication (GO:0006261) | 2.66628872 |
| 83 | pseudouridine synthesis (GO:0001522) | 2.65405094 |
| 84 | indole-containing compound metabolic process (GO:0042430) | 2.65335370 |
| 85 | transcription from mitochondrial promoter (GO:0006390) | 2.64697750 |
| 86 | organelle membrane fusion (GO:0090174) | 2.63640993 |
| 87 | protein neddylation (GO:0045116) | 2.61131099 |
| 88 | branched-chain amino acid catabolic process (GO:0009083) | 2.60594670 |
| 89 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.60559606 |
| 90 | hydrogen ion transmembrane transport (GO:1902600) | 2.60275224 |
| 91 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.59222329 |
| 92 | response to interferon-beta (GO:0035456) | 2.58014896 |
| 93 | termination of RNA polymerase I transcription (GO:0006363) | 2.57098721 |
| 94 | proton transport (GO:0015992) | 2.56968536 |
| 95 | hydrogen transport (GO:0006818) | 2.56740080 |
| 96 | cellular response to interferon-beta (GO:0035458) | 2.56272212 |
| 97 | peptidyl-histidine modification (GO:0018202) | 2.55894532 |
| 98 | negative regulation of ligase activity (GO:0051352) | 2.52363753 |
| 99 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.52363753 |
| 100 | protein deneddylation (GO:0000338) | 2.51465042 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VDR_22108803_ChIP-Seq_LS180_Human | 3.83682409 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.32174386 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.22001127 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.10745485 |
| 5 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.63919432 |
| 6 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.61340019 |
| 7 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.46079875 |
| 8 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.43278598 |
| 9 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.36867046 |
| 10 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.28328258 |
| 11 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.17178553 |
| 12 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.13942193 |
| 13 | EWS_26573619_Chip-Seq_HEK293_Human | 2.13200730 |
| 14 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.12665396 |
| 15 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.10876105 |
| 16 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.07676619 |
| 17 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.06143561 |
| 18 | FUS_26573619_Chip-Seq_HEK293_Human | 2.05111315 |
| 19 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.00054752 |
| 20 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.97358678 |
| 21 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.89134180 |
| 22 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.84819183 |
| 23 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.84195796 |
| 24 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.82568764 |
| 25 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.79290569 |
| 26 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.75416254 |
| 27 | P300_19829295_ChIP-Seq_ESCs_Human | 1.68377527 |
| 28 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.66533727 |
| 29 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.66403158 |
| 30 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.62983058 |
| 31 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.61509227 |
| 32 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.59549130 |
| 33 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.59371602 |
| 34 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.58297788 |
| 35 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.58102084 |
| 36 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.55778961 |
| 37 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.55074003 |
| 38 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.51952077 |
| 39 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.51720889 |
| 40 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.51720889 |
| 41 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.47200684 |
| 42 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.46365867 |
| 43 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.43817757 |
| 44 | AR_20517297_ChIP-Seq_VCAP_Human | 1.43587746 |
| 45 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.43148974 |
| 46 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.42966425 |
| 47 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.42441781 |
| 48 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.41932807 |
| 49 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.41932807 |
| 50 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.38042997 |
| 51 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.38015358 |
| 52 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.37479253 |
| 53 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.37354116 |
| 54 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.36764120 |
| 55 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.36262337 |
| 56 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.35871171 |
| 57 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.32497386 |
| 58 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.32415715 |
| 59 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.30328342 |
| 60 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.26422681 |
| 61 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.25986154 |
| 62 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.25986154 |
| 63 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.25967608 |
| 64 | NCOR_22424771_ChIP-Seq_293T_Human | 1.24604012 |
| 65 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.23768558 |
| 66 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.21707164 |
| 67 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.21592344 |
| 68 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.21107254 |
| 69 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.20507234 |
| 70 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.18675920 |
| 71 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.18474328 |
| 72 | AR_25329375_ChIP-Seq_VCAP_Human | 1.18209006 |
| 73 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.17632734 |
| 74 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.17166621 |
| 75 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.16785177 |
| 76 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.14686512 |
| 77 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.13068350 |
| 78 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.12406559 |
| 79 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.12208396 |
| 80 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.12008817 |
| 81 | GATA3_26560356_Chip-Seq_TH2_Human | 1.10938992 |
| 82 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.10677579 |
| 83 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.10470563 |
| 84 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.09905748 |
| 85 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.08870141 |
| 86 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.08706745 |
| 87 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.07264000 |
| 88 | TCF4_23295773_ChIP-Seq_U87_Human | 1.07180021 |
| 89 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.04628742 |
| 90 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.04443637 |
| 91 | CBP_21632823_ChIP-Seq_H3396_Human | 1.04338250 |
| 92 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.04268501 |
| 93 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.04074006 |
| 94 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.02124577 |
| 95 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.01994634 |
| 96 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.01954984 |
| 97 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.01368501 |
| 98 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.01209989 |
| 99 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 0.97711302 |
| 100 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.95402181 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003806_abnormal_nucleotide_metabolis | 6.00818168 |
| 2 | MP0002138_abnormal_hepatobiliary_system | 3.84132522 |
| 3 | MP0000569_abnormal_digit_pigmentation | 3.83613159 |
| 4 | MP0008875_abnormal_xenobiotic_pharmacok | 3.43449013 |
| 5 | MP0010386_abnormal_urinary_bladder | 3.35488019 |
| 6 | MP0003880_abnormal_central_pattern | 3.14802030 |
| 7 | MP0006072_abnormal_retinal_apoptosis | 3.00840190 |
| 8 | MP0001968_abnormal_touch/_nociception | 2.97679584 |
| 9 | MP0001835_abnormal_antigen_presentation | 2.92787418 |
| 10 | MP0003195_calcinosis | 2.72951672 |
| 11 | MP0003787_abnormal_imprinting | 2.51039203 |
| 12 | MP0005645_abnormal_hypothalamus_physiol | 2.38422918 |
| 13 | MP0008058_abnormal_DNA_repair | 2.22563727 |
| 14 | MP0008872_abnormal_physiological_respon | 2.10760065 |
| 15 | MP0006054_spinal_hemorrhage | 2.09279567 |
| 16 | MP0001529_abnormal_vocalization | 2.04468126 |
| 17 | MP0002638_abnormal_pupillary_reflex | 1.99921743 |
| 18 | MP0009697_abnormal_copulation | 1.79452038 |
| 19 | MP0003186_abnormal_redox_activity | 1.71990507 |
| 20 | MP0005174_abnormal_tail_pigmentation | 1.70649587 |
| 21 | MP0005646_abnormal_pituitary_gland | 1.70462734 |
| 22 | MP0000372_irregular_coat_pigmentation | 1.69771432 |
| 23 | MP0002272_abnormal_nervous_system | 1.67906987 |
| 24 | MP0009046_muscle_twitch | 1.66826389 |
| 25 | MP0004145_abnormal_muscle_electrophysio | 1.65052690 |
| 26 | MP0003950_abnormal_plasma_membrane | 1.64111100 |
| 27 | MP0002837_dystrophic_cardiac_calcinosis | 1.59756762 |
| 28 | MP0005075_abnormal_melanosome_morpholog | 1.59736021 |
| 29 | MP0002736_abnormal_nociception_after | 1.58135938 |
| 30 | MP0005408_hypopigmentation | 1.56166979 |
| 31 | MP0006036_abnormal_mitochondrial_physio | 1.54008105 |
| 32 | MP0003786_premature_aging | 1.50684322 |
| 33 | MP0000015_abnormal_ear_pigmentation | 1.49509712 |
| 34 | MP0002751_abnormal_autonomic_nervous | 1.47887328 |
| 35 | MP0006035_abnormal_mitochondrial_morpho | 1.39528707 |
| 36 | MP0001905_abnormal_dopamine_level | 1.37274056 |
| 37 | MP0006292_abnormal_olfactory_placode | 1.36716335 |
| 38 | MP0008877_abnormal_DNA_methylation | 1.36532567 |
| 39 | MP0000427_abnormal_hair_cycle | 1.36478969 |
| 40 | MP0009745_abnormal_behavioral_response | 1.32319526 |
| 41 | MP0002095_abnormal_skin_pigmentation | 1.28841236 |
| 42 | MP0000538_abnormal_urinary_bladder | 1.28119600 |
| 43 | MP0005253_abnormal_eye_physiology | 1.25887230 |
| 44 | MP0001984_abnormal_olfaction | 1.23032184 |
| 45 | MP0006276_abnormal_autonomic_nervous | 1.22133830 |
| 46 | MP0000631_abnormal_neuroendocrine_gland | 1.20477319 |
| 47 | MP0004215_abnormal_myocardial_fiber | 1.15866114 |
| 48 | MP0005551_abnormal_eye_electrophysiolog | 1.15187768 |
| 49 | MP0005671_abnormal_response_to | 1.09097839 |
| 50 | MP0001970_abnormal_pain_threshold | 1.08747717 |
| 51 | MP0005220_abnormal_exocrine_pancreas | 1.07448784 |
| 52 | MP0002102_abnormal_ear_morphology | 1.06295321 |
| 53 | MP0004142_abnormal_muscle_tone | 1.06059704 |
| 54 | MP0005389_reproductive_system_phenotype | 1.04642917 |
| 55 | MP0002234_abnormal_pharynx_morphology | 1.04057276 |
| 56 | MP0002909_abnormal_adrenal_gland | 1.03737335 |
| 57 | MP0009780_abnormal_chondrocyte_physiolo | 1.02157212 |
| 58 | MP0005636_abnormal_mineral_homeostasis | 1.00776997 |
| 59 | MP0003137_abnormal_impulse_conducting | 0.98388155 |
| 60 | MP0003252_abnormal_bile_duct | 0.94899583 |
| 61 | MP0009785_altered_susceptibility_to | 0.94395917 |
| 62 | MP0002166_altered_tumor_susceptibility | 0.93740535 |
| 63 | MP0003866_abnormal_defecation | 0.93187762 |
| 64 | MP0005332_abnormal_amino_acid | 0.90872285 |
| 65 | MP0008995_early_reproductive_senescence | 0.89973218 |
| 66 | MP0002938_white_spotting | 0.88430343 |
| 67 | MP0002733_abnormal_thermal_nociception | 0.87359422 |
| 68 | MP0005083_abnormal_biliary_tract | 0.86494390 |
| 69 | MP0000639_abnormal_adrenal_gland | 0.85471190 |
| 70 | MP0000613_abnormal_salivary_gland | 0.84023555 |
| 71 | MP0005410_abnormal_fertilization | 0.81337825 |
| 72 | MP0001440_abnormal_grooming_behavior | 0.80901151 |
| 73 | MP0002693_abnormal_pancreas_physiology | 0.80323814 |
| 74 | MP0000371_diluted_coat_color | 0.79590889 |
| 75 | MP0002734_abnormal_mechanical_nocicepti | 0.78639382 |
| 76 | MP0003011_delayed_dark_adaptation | 0.78508612 |
| 77 | MP0001919_abnormal_reproductive_system | 0.77311747 |
| 78 | MP0002067_abnormal_sensory_capabilities | 0.76777044 |
| 79 | MP0005085_abnormal_gallbladder_physiolo | 0.76582924 |
| 80 | MP0005386_behavior/neurological_phenoty | 0.76576831 |
| 81 | MP0004924_abnormal_behavior | 0.76576831 |
| 82 | MP0004484_altered_response_of | 0.75266687 |
| 83 | MP0002735_abnormal_chemical_nociception | 0.74738122 |
| 84 | MP0005266_abnormal_metabolism | 0.74605983 |
| 85 | MP0000358_abnormal_cell_content/ | 0.74493582 |
| 86 | MP0004147_increased_porphyrin_level | 0.73046733 |
| 87 | MP0002876_abnormal_thyroid_physiology | 0.73020214 |
| 88 | MP0000013_abnormal_adipose_tissue | 0.70942552 |
| 89 | MP0002006_tumorigenesis | 0.70306467 |
| 90 | MP0002572_abnormal_emotion/affect_behav | 0.70089962 |
| 91 | MP0001765_abnormal_ion_homeostasis | 0.68787261 |
| 92 | MP0001800_abnormal_humoral_immune | 0.68247938 |
| 93 | MP0005171_absent_coat_pigmentation | 0.67723590 |
| 94 | MP0002163_abnormal_gland_morphology | 0.67593790 |
| 95 | MP0004043_abnormal_pH_regulation | 0.67515738 |
| 96 | MP0005084_abnormal_gallbladder_morpholo | 0.67304998 |
| 97 | MP0002160_abnormal_reproductive_system | 0.65809407 |
| 98 | MP0003121_genomic_imprinting | 0.65641984 |
| 99 | MP0001756_abnormal_urination | 0.64887606 |
| 100 | MP0001790_abnormal_immune_system | 0.60832423 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.47413897 |
| 2 | 3-Methylglutaconic aciduria (HP:0003535) | 4.39788195 |
| 3 | Progressive macrocephaly (HP:0004481) | 4.14989147 |
| 4 | Mitochondrial inheritance (HP:0001427) | 4.10674358 |
| 5 | Hepatocellular necrosis (HP:0001404) | 4.09209194 |
| 6 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.85186142 |
| 7 | Congenital, generalized hypertrichosis (HP:0004540) | 3.83906872 |
| 8 | Acute encephalopathy (HP:0006846) | 3.80474339 |
| 9 | Increased CSF lactate (HP:0002490) | 3.77372416 |
| 10 | Hepatic necrosis (HP:0002605) | 3.41496602 |
| 11 | Large for gestational age (HP:0001520) | 3.32397392 |
| 12 | Methylmalonic acidemia (HP:0002912) | 3.24514789 |
| 13 | Congenital stationary night blindness (HP:0007642) | 3.18080203 |
| 14 | Exertional dyspnea (HP:0002875) | 3.09372715 |
| 15 | Hypothermia (HP:0002045) | 2.97660378 |
| 16 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.83299070 |
| 17 | Amelogenesis imperfecta (HP:0000705) | 2.81566319 |
| 18 | Hypoproteinemia (HP:0003075) | 2.81218052 |
| 19 | Abnormality of the pancreatic islet cells (HP:0006476) | 2.78565570 |
| 20 | Abnormality of endocrine pancreas physiology (HP:0012093) | 2.78565570 |
| 21 | Ketoacidosis (HP:0001993) | 2.78345587 |
| 22 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.77111892 |
| 23 | B lymphocytopenia (HP:0010976) | 2.74689076 |
| 24 | Pancreatic cysts (HP:0001737) | 2.73816591 |
| 25 | Abnormality of methionine metabolism (HP:0010901) | 2.71061101 |
| 26 | Increased serum lactate (HP:0002151) | 2.69793003 |
| 27 | Hyperventilation (HP:0002883) | 2.60548922 |
| 28 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.55243067 |
| 29 | Nephronophthisis (HP:0000090) | 2.52633076 |
| 30 | Abnormality of B cell number (HP:0010975) | 2.49323563 |
| 31 | Lactic acidosis (HP:0003128) | 2.48294589 |
| 32 | Respiratory failure (HP:0002878) | 2.47597752 |
| 33 | Cerebral edema (HP:0002181) | 2.43180861 |
| 34 | Renal Fanconi syndrome (HP:0001994) | 2.42363276 |
| 35 | Fair hair (HP:0002286) | 2.40256794 |
| 36 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.39445614 |
| 37 | Methylmalonic aciduria (HP:0012120) | 2.38512111 |
| 38 | Atonic seizures (HP:0010819) | 2.38404811 |
| 39 | Aplastic anemia (HP:0001915) | 2.36295810 |
| 40 | Slender build (HP:0001533) | 2.34773996 |
| 41 | Abnormality of vitamin B metabolism (HP:0004340) | 2.31621888 |
| 42 | Lethargy (HP:0001254) | 2.29830055 |
| 43 | Optic disc pallor (HP:0000543) | 2.27413302 |
| 44 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 2.26892994 |
| 45 | Hypomagnesemia (HP:0002917) | 2.26673779 |
| 46 | Abnormality of midbrain morphology (HP:0002418) | 2.22827647 |
| 47 | Molar tooth sign on MRI (HP:0002419) | 2.22827647 |
| 48 | Hypophosphatemic rickets (HP:0004912) | 2.15945258 |
| 49 | Stomatitis (HP:0010280) | 2.14892746 |
| 50 | Panhypogammaglobulinemia (HP:0003139) | 2.13533393 |
| 51 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.13455706 |
| 52 | Increased hepatocellular lipid droplets (HP:0006565) | 2.12825001 |
| 53 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.11886423 |
| 54 | Thyroiditis (HP:0100646) | 2.10878285 |
| 55 | True hermaphroditism (HP:0010459) | 2.09925614 |
| 56 | Testicular atrophy (HP:0000029) | 2.08926199 |
| 57 | Exercise intolerance (HP:0003546) | 2.07593503 |
| 58 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.06846367 |
| 59 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.06846367 |
| 60 | Hyperalaninemia (HP:0003348) | 2.04585649 |
| 61 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.04585649 |
| 62 | Abnormality of alanine metabolism (HP:0010916) | 2.04585649 |
| 63 | Woolly hair (HP:0002224) | 2.04112385 |
| 64 | Small hand (HP:0200055) | 2.03321410 |
| 65 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.03236690 |
| 66 | Neonatal respiratory distress (HP:0002643) | 2.01838188 |
| 67 | Abnormality of the prostate (HP:0008775) | 2.01594287 |
| 68 | Pancreatic fibrosis (HP:0100732) | 1.98801787 |
| 69 | Cerebral palsy (HP:0100021) | 1.98130938 |
| 70 | Hypoplasia of the fovea (HP:0007750) | 1.97117505 |
| 71 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 1.97117505 |
| 72 | Polydipsia (HP:0001959) | 1.96927524 |
| 73 | Abnormal drinking behavior (HP:0030082) | 1.96927524 |
| 74 | Medial flaring of the eyebrow (HP:0010747) | 1.94728371 |
| 75 | Abnormality of the renal medulla (HP:0100957) | 1.94588305 |
| 76 | Oral leukoplakia (HP:0002745) | 1.91898866 |
| 77 | Abnormality of serum amino acid levels (HP:0003112) | 1.91564451 |
| 78 | Spastic paraparesis (HP:0002313) | 1.91493454 |
| 79 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.90171048 |
| 80 | Type II lissencephaly (HP:0007260) | 1.87695240 |
| 81 | Generalized hypopigmentation of hair (HP:0011358) | 1.86413970 |
| 82 | Abnormality of magnesium homeostasis (HP:0004921) | 1.84991237 |
| 83 | Dysdiadochokinesis (HP:0002075) | 1.83903681 |
| 84 | Abnormality of the axillary hair (HP:0100134) | 1.83407907 |
| 85 | Abnormality of secondary sexual hair (HP:0009888) | 1.83407907 |
| 86 | IgG deficiency (HP:0004315) | 1.83147660 |
| 87 | Abnormality of the renal cortex (HP:0011035) | 1.82049254 |
| 88 | Pancytopenia (HP:0001876) | 1.80863311 |
| 89 | Homocystinuria (HP:0002156) | 1.80301362 |
| 90 | Abnormality of homocysteine metabolism (HP:0010919) | 1.80301362 |
| 91 | Thyroid-stimulating hormone excess (HP:0002925) | 1.80292492 |
| 92 | Hyperinsulinemic hypoglycemia (HP:0000825) | 1.79641441 |
| 93 | CNS demyelination (HP:0007305) | 1.79631732 |
| 94 | Volvulus (HP:0002580) | 1.78713642 |
| 95 | Gaze-evoked nystagmus (HP:0000640) | 1.78309940 |
| 96 | Ketosis (HP:0001946) | 1.78268412 |
| 97 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.75671884 |
| 98 | Megaloblastic anemia (HP:0001889) | 1.75148318 |
| 99 | Hypoplasia of the uterus (HP:0000013) | 1.75071328 |
| 100 | Intestinal atresia (HP:0011100) | 1.73139350 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EIF2AK3 | 4.96437611 |
| 2 | FRK | 3.79342959 |
| 3 | EIF2AK1 | 3.75941593 |
| 4 | NUAK1 | 3.22389822 |
| 5 | TLK1 | 3.07066628 |
| 6 | VRK2 | 2.96685126 |
| 7 | MAP3K12 | 2.61176428 |
| 8 | TRIM28 | 2.52233716 |
| 9 | BMPR1B | 2.23356166 |
| 10 | ERBB3 | 1.93182268 |
| 11 | WNK3 | 1.85590993 |
| 12 | MYLK | 1.83363180 |
| 13 | WNK4 | 1.78151811 |
| 14 | ZAK | 1.77616255 |
| 15 | TXK | 1.77231027 |
| 16 | MAP4K2 | 1.72926566 |
| 17 | SCYL2 | 1.68312717 |
| 18 | MST4 | 1.66535694 |
| 19 | ADRBK2 | 1.50085237 |
| 20 | STK39 | 1.45633807 |
| 21 | PINK1 | 1.43724326 |
| 22 | TNIK | 1.43009372 |
| 23 | GRK1 | 1.41840408 |
| 24 | TAOK3 | 1.40768341 |
| 25 | NEK1 | 1.40213961 |
| 26 | PLK2 | 1.36215965 |
| 27 | CSNK1G3 | 1.32912381 |
| 28 | TSSK6 | 1.26436282 |
| 29 | PASK | 1.26011431 |
| 30 | VRK1 | 1.24905703 |
| 31 | CSNK1G1 | 1.18925157 |
| 32 | OXSR1 | 1.18155389 |
| 33 | TIE1 | 1.11759073 |
| 34 | PHKG2 | 1.11545318 |
| 35 | PHKG1 | 1.11545318 |
| 36 | PLK3 | 1.07800810 |
| 37 | MKNK2 | 1.07800237 |
| 38 | CSNK1G2 | 1.06322499 |
| 39 | MKNK1 | 1.06156055 |
| 40 | PRKCE | 1.01534706 |
| 41 | INSRR | 1.00491555 |
| 42 | DYRK2 | 0.96506401 |
| 43 | MAP4K1 | 0.94003166 |
| 44 | AKT3 | 0.93301588 |
| 45 | GRK5 | 0.90482571 |
| 46 | GRK6 | 0.78335597 |
| 47 | CSNK1A1L | 0.78087311 |
| 48 | EIF2AK2 | 0.77089710 |
| 49 | RPS6KA5 | 0.73752320 |
| 50 | CSNK1A1 | 0.71972156 |
| 51 | CASK | 0.69063162 |
| 52 | KIT | 0.68947178 |
| 53 | PRKCI | 0.68886929 |
| 54 | SYK | 0.67710804 |
| 55 | STK16 | 0.66072544 |
| 56 | PAK3 | 0.63851743 |
| 57 | TEC | 0.60995108 |
| 58 | ATR | 0.60169372 |
| 59 | PRKCG | 0.59765398 |
| 60 | TGFBR1 | 0.58715848 |
| 61 | CAMK2D | 0.56600847 |
| 62 | STK38L | 0.56401586 |
| 63 | LIMK1 | 0.54679256 |
| 64 | NTRK3 | 0.54369973 |
| 65 | ILK | 0.53260930 |
| 66 | MAPKAPK5 | 0.51710937 |
| 67 | ABL1 | 0.51578868 |
| 68 | RIPK4 | 0.49743362 |
| 69 | FER | 0.48417249 |
| 70 | PLK1 | 0.47929615 |
| 71 | RPS6KA4 | 0.47803604 |
| 72 | LYN | 0.47377910 |
| 73 | PRKG1 | 0.46719579 |
| 74 | EPHA4 | 0.43731008 |
| 75 | PRKACA | 0.43687885 |
| 76 | TAF1 | 0.43670270 |
| 77 | PRKCA | 0.43090129 |
| 78 | WEE1 | 0.41763022 |
| 79 | ADRBK1 | 0.41472382 |
| 80 | GRK7 | 0.41014979 |
| 81 | NLK | 0.40069406 |
| 82 | DMPK | 0.39689426 |
| 83 | ATM | 0.39173416 |
| 84 | OBSCN | 0.38775917 |
| 85 | FLT3 | 0.37091900 |
| 86 | DAPK1 | 0.36147496 |
| 87 | TYK2 | 0.35010450 |
| 88 | MUSK | 0.34869747 |
| 89 | IKBKB | 0.34775455 |
| 90 | STK3 | 0.34227820 |
| 91 | ALK | 0.33559177 |
| 92 | DYRK3 | 0.32892570 |
| 93 | CSNK2A2 | 0.32790752 |
| 94 | PIK3CG | 0.32314172 |
| 95 | BCKDK | 0.32278956 |
| 96 | AURKB | 0.31896308 |
| 97 | PTK2B | 0.31228738 |
| 98 | CSNK2A1 | 0.29648275 |
| 99 | FES | 0.29286561 |
| 100 | MAPK13 | 0.29197270 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Caffeine metabolism_Homo sapiens_hsa00232 | 4.78700812 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 3.81851344 |
| 3 | Asthma_Homo sapiens_hsa05310 | 3.37120657 |
| 4 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.20793451 |
| 5 | Protein export_Homo sapiens_hsa03060 | 2.92525838 |
| 6 | Allograft rejection_Homo sapiens_hsa05330 | 2.64885979 |
| 7 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.59938644 |
| 8 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.55498200 |
| 9 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.44884826 |
| 10 | Parkinsons disease_Homo sapiens_hsa05012 | 2.34109053 |
| 11 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.18227585 |
| 12 | RNA polymerase_Homo sapiens_hsa03020 | 2.08825446 |
| 13 | Phototransduction_Homo sapiens_hsa04744 | 1.74303948 |
| 14 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.71025197 |
| 15 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.65770916 |
| 16 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.61541362 |
| 17 | Alzheimers disease_Homo sapiens_hsa05010 | 1.60748952 |
| 18 | Huntingtons disease_Homo sapiens_hsa05016 | 1.58103184 |
| 19 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.57242912 |
| 20 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.51418258 |
| 21 | Homologous recombination_Homo sapiens_hsa03440 | 1.47807996 |
| 22 | RNA degradation_Homo sapiens_hsa03018 | 1.44379558 |
| 23 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.43978536 |
| 24 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.43867821 |
| 25 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.43297350 |
| 26 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.41244858 |
| 27 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.41139041 |
| 28 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.39380074 |
| 29 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.32720432 |
| 30 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.27293392 |
| 31 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.19136603 |
| 32 | Basal transcription factors_Homo sapiens_hsa03022 | 1.18635312 |
| 33 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.18071916 |
| 34 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.17798217 |
| 35 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.16467651 |
| 36 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.15305533 |
| 37 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.11615631 |
| 38 | Mismatch repair_Homo sapiens_hsa03430 | 1.09451157 |
| 39 | Viral myocarditis_Homo sapiens_hsa05416 | 1.08814323 |
| 40 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.07877302 |
| 41 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.02365680 |
| 42 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.94205379 |
| 43 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.93237303 |
| 44 | Ribosome_Homo sapiens_hsa03010 | 0.93211897 |
| 45 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.92978421 |
| 46 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.92622072 |
| 47 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.92426094 |
| 48 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.91332126 |
| 49 | Olfactory transduction_Homo sapiens_hsa04740 | 0.91264073 |
| 50 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.90051337 |
| 51 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.89475786 |
| 52 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.89083038 |
| 53 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.89023947 |
| 54 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.88496639 |
| 55 | Purine metabolism_Homo sapiens_hsa00230 | 0.86014625 |
| 56 | Nicotine addiction_Homo sapiens_hsa05033 | 0.84013719 |
| 57 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.83961120 |
| 58 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.83741441 |
| 59 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.81172014 |
| 60 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.79343017 |
| 61 | DNA replication_Homo sapiens_hsa03030 | 0.77272929 |
| 62 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.74417055 |
| 63 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.72809181 |
| 64 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.71082953 |
| 65 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.66032365 |
| 66 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.62908998 |
| 67 | Metabolic pathways_Homo sapiens_hsa01100 | 0.60484498 |
| 68 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.59552008 |
| 69 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.59325683 |
| 70 | Peroxisome_Homo sapiens_hsa04146 | 0.59227091 |
| 71 | GABAergic synapse_Homo sapiens_hsa04727 | 0.57983906 |
| 72 | Morphine addiction_Homo sapiens_hsa05032 | 0.55192217 |
| 73 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.53583290 |
| 74 | RNA transport_Homo sapiens_hsa03013 | 0.53538869 |
| 75 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.53038131 |
| 76 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.52707518 |
| 77 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.49750603 |
| 78 | Salivary secretion_Homo sapiens_hsa04970 | 0.46748820 |
| 79 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.44951546 |
| 80 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.42983149 |
| 81 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.42690033 |
| 82 | Spliceosome_Homo sapiens_hsa03040 | 0.42490814 |
| 83 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.42419624 |
| 84 | Phagosome_Homo sapiens_hsa04145 | 0.38890037 |
| 85 | Circadian entrainment_Homo sapiens_hsa04713 | 0.38383871 |
| 86 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.37697301 |
| 87 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.34864272 |
| 88 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.33961816 |
| 89 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.33552493 |
| 90 | Retinol metabolism_Homo sapiens_hsa00830 | 0.32642602 |
| 91 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.32114044 |
| 92 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.29172796 |
| 93 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.28841211 |
| 94 | Leishmaniasis_Homo sapiens_hsa05140 | 0.28294864 |
| 95 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.27144707 |
| 96 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.26669238 |
| 97 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.26407019 |
| 98 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.25956406 |
| 99 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.24793475 |
| 100 | Insulin secretion_Homo sapiens_hsa04911 | 0.23642245 |

