Rank | Gene Set | Z-score |
---|---|---|
1 | locomotory exploration behavior (GO:0035641) | 5.24435595 |
2 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 4.95447897 |
3 | synaptic vesicle maturation (GO:0016188) | 4.53017866 |
4 | vocalization behavior (GO:0071625) | 4.49477014 |
5 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 4.44970960 |
6 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 4.41327798 |
7 | layer formation in cerebral cortex (GO:0021819) | 4.33073686 |
8 | neuron cell-cell adhesion (GO:0007158) | 4.31231637 |
9 | regulation of synaptic vesicle exocytosis (GO:2000300) | 4.28157674 |
10 | hemidesmosome assembly (GO:0031581) | 4.24572598 |
11 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 4.20387866 |
12 | synaptic vesicle exocytosis (GO:0016079) | 4.15344534 |
13 | exploration behavior (GO:0035640) | 4.12383977 |
14 | protein localization to synapse (GO:0035418) | 4.03355747 |
15 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 3.96600730 |
16 | dendritic spine morphogenesis (GO:0060997) | 3.92920805 |
17 | glutamate secretion (GO:0014047) | 3.90508644 |
18 | regulation of glutamate receptor signaling pathway (GO:1900449) | 3.87648093 |
19 | neuron recognition (GO:0008038) | 3.76156466 |
20 | axonal fasciculation (GO:0007413) | 3.72445312 |
21 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 3.71382291 |
22 | glutamate receptor signaling pathway (GO:0007215) | 3.68880342 |
23 | dendrite morphogenesis (GO:0048813) | 3.64183586 |
24 | regulation of synaptic vesicle transport (GO:1902803) | 3.61419040 |
25 | cell migration in hindbrain (GO:0021535) | 3.58023939 |
26 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 3.55786744 |
27 | regulation of neuronal synaptic plasticity (GO:0048168) | 3.47880250 |
28 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 3.45884441 |
29 | neurotransmitter secretion (GO:0007269) | 3.44653586 |
30 | neuronal action potential propagation (GO:0019227) | 3.41267243 |
31 | synaptic vesicle endocytosis (GO:0048488) | 3.41159379 |
32 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.39841055 |
33 | regulation of dendritic spine morphogenesis (GO:0061001) | 3.37587717 |
34 | presynaptic membrane organization (GO:0097090) | 3.30506900 |
35 | synaptic transmission, glutamatergic (GO:0035249) | 3.30319829 |
36 | innervation (GO:0060384) | 3.29003999 |
37 | neuromuscular process controlling balance (GO:0050885) | 3.24576748 |
38 | cerebellar Purkinje cell differentiation (GO:0021702) | 3.22414250 |
39 | apical protein localization (GO:0045176) | 3.17716681 |
40 | activation of protein kinase A activity (GO:0034199) | 3.17426808 |
41 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 3.15835902 |
42 | neuron-neuron synaptic transmission (GO:0007270) | 3.14943337 |
43 | central nervous system projection neuron axonogenesis (GO:0021952) | 3.13953721 |
44 | gamma-aminobutyric acid transport (GO:0015812) | 3.11890483 |
45 | regulation of synapse structural plasticity (GO:0051823) | 3.11614649 |
46 | positive regulation of synapse maturation (GO:0090129) | 3.11257172 |
47 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 3.09489564 |
48 | proline transport (GO:0015824) | 3.08519466 |
49 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 3.07434464 |
50 | long-term memory (GO:0007616) | 3.05555434 |
51 | regulation of cAMP-dependent protein kinase activity (GO:2000479) | 3.04364263 |
52 | cellular potassium ion homeostasis (GO:0030007) | 3.03759793 |
53 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.03177254 |
54 | regulation of postsynaptic membrane potential (GO:0060078) | 3.02718108 |
55 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 2.99605594 |
56 | heart field specification (GO:0003128) | 2.99557970 |
57 | secondary heart field specification (GO:0003139) | 2.99557970 |
58 | establishment of nucleus localization (GO:0040023) | 2.93518512 |
59 | transmission of nerve impulse (GO:0019226) | 2.89532735 |
60 | long-term synaptic potentiation (GO:0060291) | 2.87644878 |
61 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 2.85381550 |
62 | regulation of synaptic plasticity (GO:0048167) | 2.85197480 |
63 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 2.85114039 |
64 | membrane assembly (GO:0071709) | 2.84447341 |
65 | synapse assembly (GO:0007416) | 2.83958014 |
66 | auditory behavior (GO:0031223) | 2.83863142 |
67 | cerebellar granule cell differentiation (GO:0021707) | 2.83463244 |
68 | establishment of mitochondrion localization, microtubule-mediated (GO:0034643) | 2.81627619 |
69 | mitochondrion transport along microtubule (GO:0047497) | 2.81627619 |
70 | postsynaptic membrane organization (GO:0001941) | 2.81610340 |
71 | organelle transport along microtubule (GO:0072384) | 2.81102665 |
72 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.80310440 |
73 | regulation of neurotransmitter secretion (GO:0046928) | 2.80031721 |
74 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 2.79374731 |
75 | regulation of respiratory system process (GO:0044065) | 2.79330269 |
76 | neurotransmitter transport (GO:0006836) | 2.78827117 |
77 | sodium ion export (GO:0071436) | 2.76932037 |
78 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 2.76480824 |
79 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 2.76339321 |
80 | cell communication by electrical coupling (GO:0010644) | 2.76270224 |
81 | regulation of clathrin-mediated endocytosis (GO:2000369) | 2.75020773 |
82 | behavioral fear response (GO:0001662) | 2.74663025 |
83 | behavioral defense response (GO:0002209) | 2.74663025 |
84 | regulation of dendritic spine development (GO:0060998) | 2.74315221 |
85 | regulation of vesicle fusion (GO:0031338) | 2.73337961 |
86 | positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 2.73128296 |
87 | vesicle transport along microtubule (GO:0047496) | 2.73029106 |
88 | cell communication involved in cardiac conduction (GO:0086065) | 2.72954506 |
89 | dendritic spine organization (GO:0097061) | 2.72388378 |
90 | neuromuscular process (GO:0050905) | 2.72290768 |
91 | axon extension (GO:0048675) | 2.71707318 |
92 | synapse organization (GO:0050808) | 2.69355097 |
93 | paraxial mesoderm development (GO:0048339) | 2.65730312 |
94 | establishment of mitochondrion localization (GO:0051654) | 2.64691431 |
95 | positive regulation of membrane potential (GO:0045838) | 2.64568896 |
96 | neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976) | 2.63538368 |
97 | positive regulation of dendritic spine development (GO:0060999) | 2.63505712 |
98 | presynaptic membrane assembly (GO:0097105) | 2.63505304 |
99 | asymmetric protein localization (GO:0008105) | 2.62713992 |
100 | regulation of axon extension involved in axon guidance (GO:0048841) | 2.62615483 |
101 | learning (GO:0007612) | 2.62190606 |
102 | righting reflex (GO:0060013) | 2.61470030 |
103 | desmosome organization (GO:0002934) | 2.59900935 |
104 | negative regulation of dendrite morphogenesis (GO:0050774) | 2.59796966 |
105 | prepulse inhibition (GO:0060134) | 2.59202390 |
106 | fear response (GO:0042596) | 2.57240204 |
107 | response to auditory stimulus (GO:0010996) | 2.55839477 |
108 | startle response (GO:0001964) | 2.55479938 |
109 | regulation of ARF protein signal transduction (GO:0032012) | 2.55077228 |
110 | neuronal ion channel clustering (GO:0045161) | 2.54509011 |
111 | amino acid import (GO:0043090) | 2.54148327 |
112 | mating behavior (GO:0007617) | 2.53452186 |
113 | regulation of neurotransmitter transport (GO:0051588) | 2.52680714 |
114 | neuron projection extension (GO:1990138) | 2.52548863 |
115 | regulation of axon guidance (GO:1902667) | 2.44915654 |
116 | cellular sodium ion homeostasis (GO:0006883) | 2.42102776 |
117 | cerebral cortex radially oriented cell migration (GO:0021799) | 2.37556950 |
118 | negative regulation of keratinocyte proliferation (GO:0010839) | 2.34787390 |
119 | peripheral nervous system axon ensheathment (GO:0032292) | 2.34460040 |
120 | myelination in peripheral nervous system (GO:0022011) | 2.34460040 |
121 | potassium ion homeostasis (GO:0055075) | 2.30588605 |
122 | suckling behavior (GO:0001967) | 2.30367609 |
123 | regulation of synapse assembly (GO:0051963) | 2.28803879 |
124 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 2.28582064 |
125 | axon extension involved in axon guidance (GO:0048846) | 2.28582064 |
126 | cell adhesion mediated by integrin (GO:0033627) | 2.28455042 |
127 | positive regulation of synapse assembly (GO:0051965) | 2.27224087 |
128 | cell-substrate junction assembly (GO:0007044) | 2.25393858 |
129 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 2.23085510 |
130 | cerebellar Purkinje cell layer development (GO:0021680) | 2.20807642 |
131 | negative regulation of neurotransmitter secretion (GO:0046929) | 2.20663856 |
132 | ephrin receptor signaling pathway (GO:0048013) | 2.15715127 |
133 | developmental cell growth (GO:0048588) | 2.13849480 |
134 | L-amino acid import (GO:0043092) | 2.11609935 |
135 | central nervous system neuron axonogenesis (GO:0021955) | 2.10740288 |
136 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 2.07230102 |
137 | negative regulation of dendrite development (GO:2000171) | 2.07031248 |
138 | hippo signaling (GO:0035329) | 2.06717946 |
139 | positive regulation of neurological system process (GO:0031646) | 2.06633399 |
140 | regulation of NFAT protein import into nucleus (GO:0051532) | 2.06499772 |
141 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 2.05665652 |
142 | regulation of cell communication by electrical coupling (GO:0010649) | 2.05538923 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.99275595 |
2 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.14138990 |
3 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.92871302 |
4 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.66989690 |
5 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.63218740 |
6 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.57173663 |
7 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.46394846 |
8 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.46394846 |
9 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.30915782 |
10 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.22396106 |
11 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.17426705 |
12 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.16004286 |
13 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.15116872 |
14 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.14453315 |
15 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.11444251 |
16 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.10541358 |
17 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.08915277 |
18 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.07617156 |
19 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.07510876 |
20 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.05322340 |
21 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.04790883 |
22 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.04715834 |
23 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.01797366 |
24 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.91107346 |
25 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.89601513 |
26 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.88902718 |
27 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.78327459 |
28 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.74830884 |
29 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.66670065 |
30 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.64352844 |
31 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.62979467 |
32 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.62154955 |
33 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.61053252 |
34 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.60561630 |
35 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.60225258 |
36 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.55976107 |
37 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.55918045 |
38 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.54637119 |
39 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.52908114 |
40 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.51184332 |
41 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.47031360 |
42 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.45094524 |
43 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.44306529 |
44 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.40644125 |
45 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.38681401 |
46 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.37955767 |
47 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.37748340 |
48 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.37730487 |
49 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.36381227 |
50 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.35577726 |
51 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.34658053 |
52 | TP53_16413492_ChIP-PET_HCT116_Human | 1.34266579 |
53 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.33743607 |
54 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.32878161 |
55 | STAT3_23295773_ChIP-Seq_U87_Human | 1.31348858 |
56 | AR_19668381_ChIP-Seq_PC3_Human | 1.30958783 |
57 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.29600482 |
58 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.29575199 |
59 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.28826582 |
60 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.28826582 |
61 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.28530067 |
62 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.28174492 |
63 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.27105750 |
64 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.26597679 |
65 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.26531544 |
66 | P300_19829295_ChIP-Seq_ESCs_Human | 1.25910324 |
67 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.25621701 |
68 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.24657928 |
69 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.24165981 |
70 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.24100118 |
71 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.23519636 |
72 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.22974328 |
73 | SOX9_26525672_Chip-Seq_HEART_Mouse | 1.22770020 |
74 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.22733284 |
75 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.22567535 |
76 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.21161761 |
77 | AR_25329375_ChIP-Seq_VCAP_Human | 1.20581919 |
78 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.20436842 |
79 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 1.19689623 |
80 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.19669743 |
81 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.19669374 |
82 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.18974876 |
83 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.18629464 |
84 | KDM2B_26808549_Chip-Seq_K562_Human | 1.17994983 |
85 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.17751051 |
86 | CJUN_26792858_Chip-Seq_BT549_Human | 1.15866182 |
87 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.14870161 |
88 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.14027252 |
89 | TCF4_23295773_ChIP-Seq_U87_Human | 1.11984586 |
90 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.11769809 |
91 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.11521130 |
92 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.11274726 |
93 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.11176877 |
94 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.10708728 |
95 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.10621848 |
96 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.09271001 |
97 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.08485177 |
98 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.08264144 |
99 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.08119130 |
100 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.07998866 |
101 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.06717151 |
102 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.06013713 |
103 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.06013713 |
104 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.05577836 |
105 | TBX3_20139965_ChIP-Seq_MESCs_Mouse | 1.04305412 |
106 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.03708932 |
107 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.03437471 |
108 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.03246539 |
109 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.03210523 |
110 | TBX3_20139965_ChIP-Seq_ESCs_Mouse | 1.03102330 |
111 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.02830391 |
112 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.00993320 |
113 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 1.00694726 |
114 | FUS_26573619_Chip-Seq_HEK293_Human | 1.00595663 |
115 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.00541896 |
116 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.00357008 |
117 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.00350915 |
118 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 1.00131195 |
119 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 0.99553539 |
120 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 0.99465064 |
121 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 0.99275131 |
122 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 0.98939078 |
123 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.98900883 |
124 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.98811309 |
125 | TP53_18474530_ChIP-ChIP_U2OS_Human | 0.98190576 |
126 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.97533426 |
127 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.95437337 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 5.65695681 |
2 | MP0003880_abnormal_central_pattern | 3.78354361 |
3 | MP0003635_abnormal_synaptic_transmissio | 3.68299402 |
4 | MP0004270_analgesia | 3.42533794 |
5 | MP0002063_abnormal_learning/memory/cond | 3.09152426 |
6 | MP0009745_abnormal_behavioral_response | 2.76797200 |
7 | MP0009046_muscle_twitch | 2.67572129 |
8 | MP0005423_abnormal_somatic_nervous | 2.66224103 |
9 | MP0002064_seizures | 2.63065396 |
10 | MP0002572_abnormal_emotion/affect_behav | 2.55538191 |
11 | MP0000778_abnormal_nervous_system | 2.46321950 |
12 | MP0001968_abnormal_touch/_nociception | 2.44968509 |
13 | MP0001486_abnormal_startle_reflex | 2.38497714 |
14 | MP0002734_abnormal_mechanical_nocicepti | 2.31392728 |
15 | MP0003941_abnormal_skin_development | 2.21544957 |
16 | MP0000569_abnormal_digit_pigmentation | 2.11743989 |
17 | MP0003705_abnormal_hypodermis_morpholog | 2.06467461 |
18 | MP0002272_abnormal_nervous_system | 2.04870916 |
19 | MP0004885_abnormal_endolymph | 2.03757949 |
20 | MP0002184_abnormal_innervation | 1.93018176 |
21 | MP0009780_abnormal_chondrocyte_physiolo | 1.89643237 |
22 | MP0002733_abnormal_thermal_nociception | 1.79762219 |
23 | MP0004272_abnormal_basement_membrane | 1.76749866 |
24 | MP0002067_abnormal_sensory_capabilities | 1.76139476 |
25 | MP0003787_abnormal_imprinting | 1.74701854 |
26 | MP0001440_abnormal_grooming_behavior | 1.73834524 |
27 | MP0002735_abnormal_chemical_nociception | 1.72263297 |
28 | MP0002557_abnormal_social/conspecific_i | 1.66142953 |
29 | MP0004811_abnormal_neuron_physiology | 1.64432762 |
30 | MP0001970_abnormal_pain_threshold | 1.64140989 |
31 | MP0004924_abnormal_behavior | 1.63813515 |
32 | MP0005386_behavior/neurological_phenoty | 1.63813515 |
33 | MP0000955_abnormal_spinal_cord | 1.62100479 |
34 | MP0002736_abnormal_nociception_after | 1.61777535 |
35 | MP0004858_abnormal_nervous_system | 1.58178536 |
36 | MP0001501_abnormal_sleep_pattern | 1.53203060 |
37 | MP0008569_lethality_at_weaning | 1.52501007 |
38 | MP0002882_abnormal_neuron_morphology | 1.51735375 |
39 | MP0000762_abnormal_tongue_morphology | 1.50514587 |
40 | MP0005275_abnormal_skin_tensile | 1.45769934 |
41 | MP0006276_abnormal_autonomic_nervous | 1.44548858 |
42 | MP0002909_abnormal_adrenal_gland | 1.40256503 |
43 | MP0003122_maternal_imprinting | 1.38330979 |
44 | MP0008438_abnormal_cutaneous_collagen | 1.35137985 |
45 | MP0002152_abnormal_brain_morphology | 1.34080050 |
46 | MP0000566_synostosis | 1.33303809 |
47 | MP0002066_abnormal_motor_capabilities/c | 1.31861385 |
48 | MP0005171_absent_coat_pigmentation | 1.23292092 |
49 | MP0003329_amyloid_beta_deposits | 1.23234396 |
50 | MP0005623_abnormal_meninges_morphology | 1.23102864 |
51 | MP0001299_abnormal_eye_distance/ | 1.22513497 |
52 | MP0003890_abnormal_embryonic-extraembry | 1.22169684 |
53 | MP0002822_catalepsy | 1.21984080 |
54 | MP0005257_abnormal_intraocular_pressure | 1.19079047 |
55 | MP0005646_abnormal_pituitary_gland | 1.16485444 |
56 | MP0010678_abnormal_skin_adnexa | 1.16467738 |
57 | MP0009053_abnormal_anal_canal | 1.15512441 |
58 | MP0003566_abnormal_cell_adhesion | 1.14125310 |
59 | MP0005187_abnormal_penis_morphology | 1.10578563 |
60 | MP0005645_abnormal_hypothalamus_physiol | 1.10574590 |
61 | MP0003633_abnormal_nervous_system | 1.08570624 |
62 | MP0010234_abnormal_vibrissa_follicle | 1.06022616 |
63 | MP0003861_abnormal_nervous_system | 1.05836047 |
64 | MP0010352_gastrointestinal_tract_polyps | 1.05813500 |
65 | MP0004233_abnormal_muscle_weight | 1.05599348 |
66 | MP0002697_abnormal_eye_size | 1.05479600 |
67 | MP0006072_abnormal_retinal_apoptosis | 1.05407996 |
68 | MP0003937_abnormal_limbs/digits/tail_de | 1.04227280 |
69 | MP0000751_myopathy | 1.03457141 |
70 | MP0003283_abnormal_digestive_organ | 1.02770500 |
71 | MP0005551_abnormal_eye_electrophysiolog | 1.02618676 |
72 | MP0004145_abnormal_muscle_electrophysio | 1.02606073 |
73 | MP0004742_abnormal_vestibular_system | 1.01568117 |
74 | MP0000631_abnormal_neuroendocrine_gland | 1.00194320 |
75 | MP0001984_abnormal_olfaction | 0.98436617 |
76 | MP0010368_abnormal_lymphatic_system | 0.98385577 |
77 | MP0000383_abnormal_hair_follicle | 0.97972942 |
78 | MP0001502_abnormal_circadian_rhythm | 0.97474587 |
79 | MP0002009_preneoplasia | 0.97060324 |
80 | MP0003634_abnormal_glial_cell | 0.96459960 |
81 | MP0003631_nervous_system_phenotype | 0.96025316 |
82 | MP0004142_abnormal_muscle_tone | 0.95788568 |
83 | MP0001188_hyperpigmentation | 0.94789566 |
84 | MP0001177_atelectasis | 0.92363526 |
85 | MP0010030_abnormal_orbit_morphology | 0.91271453 |
86 | MP0005248_abnormal_Harderian_gland | 0.90590500 |
87 | MP0009250_abnormal_appendicular_skeleto | 0.90265012 |
88 | MP0002752_abnormal_somatic_nervous | 0.90234527 |
89 | MP0002877_abnormal_melanocyte_morpholog | 0.90081976 |
90 | MP0001879_abnormal_lymphatic_vessel | 0.89874352 |
91 | MP0004085_abnormal_heartbeat | 0.87989925 |
92 | MP0003137_abnormal_impulse_conducting | 0.87889687 |
93 | MP0000428_abnormal_craniofacial_morphol | 0.87699870 |
94 | MP0003950_abnormal_plasma_membrane | 0.87632189 |
95 | MP0003385_abnormal_body_wall | 0.86696469 |
96 | MP0003942_abnormal_urinary_system | 0.86300656 |
97 | MP0000467_abnormal_esophagus_morphology | 0.86171519 |
98 | MP0002896_abnormal_bone_mineralization | 0.85812362 |
99 | MP0003121_genomic_imprinting | 0.85752434 |
100 | MP0000462_abnormal_digestive_system | 0.85433081 |
101 | MP0003119_abnormal_digestive_system | 0.84649059 |
102 | MP0002229_neurodegeneration | 0.83450566 |
103 | MP0001529_abnormal_vocalization | 0.82255612 |
104 | MP0000733_abnormal_muscle_development | 0.81518516 |
105 | MP0002233_abnormal_nose_morphology | 0.80936606 |
106 | MP0002060_abnormal_skin_morphology | 0.80143533 |
107 | MP0003632_abnormal_nervous_system | 0.79701157 |
108 | MP0003123_paternal_imprinting | 0.79634017 |
109 | MP0002796_impaired_skin_barrier | 0.79339759 |
110 | MP0000534_abnormal_ureter_morphology | 0.79198212 |
111 | MP0000920_abnormal_myelination | 0.78652224 |
112 | MP0000537_abnormal_urethra_morphology | 0.78449096 |
113 | MP0001963_abnormal_hearing_physiology | 0.77377361 |
114 | MP0000427_abnormal_hair_cycle | 0.77355522 |
115 | MP0003091_abnormal_cell_migration | 0.77342473 |
116 | MP0000749_muscle_degeneration | 0.76610133 |
117 | MP0003879_abnormal_hair_cell | 0.76410376 |
118 | MP0003755_abnormal_palate_morphology | 0.74486310 |
119 | MP0000647_abnormal_sebaceous_gland | 0.74425105 |
120 | MP0002177_abnormal_outer_ear | 0.74140783 |
121 | MP0005499_abnormal_olfactory_system | 0.73490070 |
122 | MP0005394_taste/olfaction_phenotype | 0.73490070 |
123 | MP0002069_abnormal_eating/drinking_beha | 0.73017682 |
124 | MP0000432_abnormal_head_morphology | 0.72831364 |
125 | MP0003938_abnormal_ear_development | 0.72789407 |
126 | MP0010386_abnormal_urinary_bladder | 0.72439773 |
127 | MP0001849_ear_inflammation | 0.71470561 |
128 | MP0005076_abnormal_cell_differentiation | 0.70746759 |
129 | MP0001943_abnormal_respiration | 0.69774066 |
130 | MP0005409_darkened_coat_color | 0.69577120 |
131 | MP0004215_abnormal_myocardial_fiber | 0.69481805 |
132 | MP0002090_abnormal_vision | 0.67597854 |
133 | MP0000579_abnormal_nail_morphology | 0.67136682 |
134 | MP0002653_abnormal_ependyma_morphology | 0.66591192 |
135 | MP0003935_abnormal_craniofacial_develop | 0.65406311 |
136 | MP0002081_perinatal_lethality | 0.64618562 |
137 | MP0010770_preweaning_lethality | 0.64415135 |
138 | MP0002082_postnatal_lethality | 0.64415135 |
139 | MP0010769_abnormal_survival | 0.64335681 |
140 | MP0002234_abnormal_pharynx_morphology | 0.63939995 |
141 | MP0001485_abnormal_pinna_reflex | 0.63473285 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Focal motor seizures (HP:0011153) | 5.29575394 |
2 | Myokymia (HP:0002411) | 4.67498009 |
3 | Focal seizures (HP:0007359) | 4.30940917 |
4 | Progressive cerebellar ataxia (HP:0002073) | 3.94610076 |
5 | Atonic seizures (HP:0010819) | 3.57910247 |
6 | Visual hallucinations (HP:0002367) | 3.51879878 |
7 | Epileptic encephalopathy (HP:0200134) | 3.50612050 |
8 | Action tremor (HP:0002345) | 3.41447010 |
9 | Febrile seizures (HP:0002373) | 3.39257516 |
10 | Genetic anticipation (HP:0003743) | 3.24520103 |
11 | Atrophic scars (HP:0001075) | 3.23842346 |
12 | Absence seizures (HP:0002121) | 3.14132962 |
13 | Aqueductal stenosis (HP:0002410) | 3.13511080 |
14 | Broad-based gait (HP:0002136) | 2.98831355 |
15 | Drooling (HP:0002307) | 2.92808239 |
16 | Excessive salivation (HP:0003781) | 2.92808239 |
17 | Termporal pattern (HP:0011008) | 2.91631407 |
18 | Insidious onset (HP:0003587) | 2.91631407 |
19 | Dysdiadochokinesis (HP:0002075) | 2.84128073 |
20 | Dialeptic seizures (HP:0011146) | 2.73054606 |
21 | Truncal ataxia (HP:0002078) | 2.68514496 |
22 | Hyperventilation (HP:0002883) | 2.66891110 |
23 | Generalized tonic-clonic seizures (HP:0002069) | 2.65272603 |
24 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.58628192 |
25 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.58482507 |
26 | Scanning speech (HP:0002168) | 2.54502963 |
27 | Gaze-evoked nystagmus (HP:0000640) | 2.51950614 |
28 | Supranuclear gaze palsy (HP:0000605) | 2.51471878 |
29 | Urinary urgency (HP:0000012) | 2.49525786 |
30 | Ankle clonus (HP:0011448) | 2.45621466 |
31 | Abnormality of the lower motor neuron (HP:0002366) | 2.41602304 |
32 | Dysmetria (HP:0001310) | 2.39261516 |
33 | Abnormality of the corticospinal tract (HP:0002492) | 2.37709713 |
34 | Mutism (HP:0002300) | 2.36761242 |
35 | Poor eye contact (HP:0000817) | 2.35306315 |
36 | Depression (HP:0000716) | 2.28425104 |
37 | Amblyopia (HP:0000646) | 2.28111513 |
38 | Narrow nasal bridge (HP:0000446) | 2.27871268 |
39 | Milia (HP:0001056) | 2.25031522 |
40 | Cerebral inclusion bodies (HP:0100314) | 2.22441193 |
41 | Impaired social interactions (HP:0000735) | 2.21757663 |
42 | Abnormal social behavior (HP:0012433) | 2.21757663 |
43 | Inappropriate behavior (HP:0000719) | 2.17120917 |
44 | Macroorchidism (HP:0000053) | 2.16765407 |
45 | Absent speech (HP:0001344) | 2.16003687 |
46 | Papilledema (HP:0001085) | 2.15202383 |
47 | Spastic gait (HP:0002064) | 2.14885757 |
48 | Pheochromocytoma (HP:0002666) | 2.12246897 |
49 | Impaired smooth pursuit (HP:0007772) | 2.10875430 |
50 | Megalencephaly (HP:0001355) | 2.08256516 |
51 | Decreased number of large peripheral myelinated nerve fibers (HP:0003387) | 2.07041855 |
52 | Abnormality of nail color (HP:0100643) | 2.06007221 |
53 | Hemiparesis (HP:0001269) | 2.03805580 |
54 | Intention tremor (HP:0002080) | 2.03538160 |
55 | Vertebral arch anomaly (HP:0008438) | 2.01529497 |
56 | Neurofibrillary tangles (HP:0002185) | 1.99596613 |
57 | Arterial tortuosity (HP:0005116) | 1.98939688 |
58 | Dysmetric saccades (HP:0000641) | 1.94899651 |
59 | Anxiety (HP:0000739) | 1.91893021 |
60 | Epileptiform EEG discharges (HP:0011182) | 1.91187707 |
61 | Agitation (HP:0000713) | 1.90909642 |
62 | Amyotrophic lateral sclerosis (HP:0007354) | 1.90618577 |
63 | Insomnia (HP:0100785) | 1.89960749 |
64 | Fetal akinesia sequence (HP:0001989) | 1.89067995 |
65 | Fragile nails (HP:0001808) | 1.89018395 |
66 | Onycholysis (HP:0001806) | 1.87451263 |
67 | Abnormality of ocular smooth pursuit (HP:0000617) | 1.87389487 |
68 | EEG with generalized epileptiform discharges (HP:0011198) | 1.86456527 |
69 | Blue irides (HP:0000635) | 1.86322394 |
70 | Postural instability (HP:0002172) | 1.86138918 |
71 | Abnormality of salivation (HP:0100755) | 1.86042226 |
72 | Hammertoe (HP:0001765) | 1.84370252 |
73 | Cutaneous finger syndactyly (HP:0010554) | 1.83682061 |
74 | Stereotypic behavior (HP:0000733) | 1.82318892 |
75 | Coronal craniosynostosis (HP:0004440) | 1.81920785 |
76 | Vascular tortuosity (HP:0004948) | 1.81702771 |
77 | Lower limb muscle weakness (HP:0007340) | 1.81683463 |
78 | Abnormal eating behavior (HP:0100738) | 1.81501362 |
79 | Abnormality of the labia minora (HP:0012880) | 1.80352363 |
80 | Aplasia involving bones of the extremities (HP:0009825) | 1.78384405 |
81 | Aplasia involving bones of the upper limbs (HP:0009823) | 1.78384405 |
82 | Aplasia of the phalanges of the hand (HP:0009802) | 1.78384405 |
83 | Exotropia (HP:0000577) | 1.78280267 |
84 | Premature rupture of membranes (HP:0001788) | 1.75682036 |
85 | Hypsarrhythmia (HP:0002521) | 1.74541343 |
86 | Papillary thyroid carcinoma (HP:0002895) | 1.74231202 |
87 | Widely spaced teeth (HP:0000687) | 1.74222878 |
88 | Plantar hyperkeratosis (HP:0007556) | 1.72611315 |
89 | Annular pancreas (HP:0001734) | 1.72172812 |
90 | Right ventricular cardiomyopathy (HP:0011663) | 1.71291673 |
91 | Pointed chin (HP:0000307) | 1.70557912 |
92 | Abnormality of the ischium (HP:0003174) | 1.70287045 |
93 | Obstructive sleep apnea (HP:0002870) | 1.69854005 |
94 | Neuroendocrine neoplasm (HP:0100634) | 1.68830364 |
95 | Impaired vibratory sensation (HP:0002495) | 1.67167924 |
96 | Protrusio acetabuli (HP:0003179) | 1.66851886 |
97 | Thickened helices (HP:0000391) | 1.66415179 |
98 | Diplopia (HP:0000651) | 1.65681621 |
99 | Abnormality of binocular vision (HP:0011514) | 1.65681621 |
100 | Torticollis (HP:0000473) | 1.65204979 |
101 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 1.65182831 |
102 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 1.65182831 |
103 | Cutaneous syndactyly (HP:0012725) | 1.64896073 |
104 | Lower limb amyotrophy (HP:0007210) | 1.64592626 |
105 | Ankyloglossia (HP:0010296) | 1.64063882 |
106 | Facial hemangioma (HP:0000329) | 1.63581936 |
107 | Shallow orbits (HP:0000586) | 1.63456520 |
108 | Fragile skin (HP:0001030) | 1.63164673 |
109 | Incomplete penetrance (HP:0003829) | 1.63086690 |
110 | Gait ataxia (HP:0002066) | 1.60523538 |
111 | Alacrima (HP:0000522) | 1.60249121 |
112 | Limb dystonia (HP:0002451) | 1.60062026 |
113 | Lower limb asymmetry (HP:0100559) | 1.59670411 |
114 | Heterotopia (HP:0002282) | 1.59481946 |
115 | Hyperthyroidism (HP:0000836) | 1.59429119 |
116 | Overgrowth (HP:0001548) | 1.59393907 |
117 | Neoplasm of the peripheral nervous system (HP:0100007) | 1.58845579 |
118 | Hypoventilation (HP:0002791) | 1.58829958 |
119 | Cubitus valgus (HP:0002967) | 1.58611982 |
120 | Sporadic (HP:0003745) | 1.58329705 |
121 | Natal tooth (HP:0000695) | 1.56974971 |
122 | Turricephaly (HP:0000262) | 1.56772792 |
123 | Hemiplegia (HP:0002301) | 1.56693847 |
124 | Pulmonic stenosis (HP:0001642) | 1.52370904 |
125 | Thick nail (HP:0001805) | 1.51462010 |
126 | Alopecia of scalp (HP:0002293) | 1.50440874 |
127 | Absent eyelashes (HP:0000561) | 1.49799129 |
128 | Akinesia (HP:0002304) | 1.48667528 |
129 | Open mouth (HP:0000194) | 1.46492480 |
130 | Hyporeflexia of lower limbs (HP:0002600) | 1.46053257 |
131 | Hyperacusis (HP:0010780) | 1.45713336 |
132 | Advanced eruption of teeth (HP:0006288) | 1.45402805 |
133 | Pterygium (HP:0001059) | 1.44587377 |
134 | Laryngomalacia (HP:0001601) | 1.43176181 |
135 | Bladder diverticulum (HP:0000015) | 1.43139377 |
136 | Missing ribs (HP:0000921) | 1.42924283 |
137 | Limited hip movement (HP:0008800) | 1.42345611 |
138 | Split foot (HP:0001839) | 1.41381368 |
139 | Neonatal short-limb short stature (HP:0008921) | 1.41328204 |
140 | Bronchomalacia (HP:0002780) | 1.39813264 |
141 | Bundle branch block (HP:0011710) | 1.38618140 |
142 | Arnold-Chiari malformation (HP:0002308) | 1.37358929 |
143 | Ulnar bowing (HP:0003031) | 1.35952356 |
144 | Hypoplastic labia majora (HP:0000059) | 1.35580801 |
145 | Overriding aorta (HP:0002623) | 1.34568277 |
146 | Relative macrocephaly (HP:0004482) | 1.33631333 |
147 | Broad metatarsal (HP:0001783) | 1.33439627 |
148 | Decreased number of peripheral myelinated nerve fibers (HP:0003380) | 1.33325774 |
149 | Hypoplasia of dental enamel (HP:0006297) | 1.32950029 |
150 | Buphthalmos (HP:0000557) | 1.32827384 |
151 | Abnormality of the astrocytes (HP:0100707) | 1.32804571 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MARK1 | 4.05006273 |
2 | NTRK3 | 3.62763235 |
3 | MAP3K9 | 3.15355266 |
4 | EPHA4 | 3.13162754 |
5 | MAP3K4 | 2.98229658 |
6 | LATS2 | 2.24626839 |
7 | MINK1 | 2.24189482 |
8 | PNCK | 2.19397085 |
9 | TYRO3 | 2.18184191 |
10 | PAK6 | 2.15987410 |
11 | NTRK2 | 2.13625492 |
12 | MAP2K7 | 1.97797449 |
13 | MET | 1.82867497 |
14 | CASK | 1.69420627 |
15 | MAP2K4 | 1.67914320 |
16 | CAMK1G | 1.63024101 |
17 | DDR2 | 1.57969531 |
18 | NTRK1 | 1.54514586 |
19 | PRKD3 | 1.46775468 |
20 | MAPK13 | 1.45985401 |
21 | KSR1 | 1.45774243 |
22 | STK38 | 1.43607071 |
23 | ICK | 1.42668320 |
24 | DAPK2 | 1.42636624 |
25 | KSR2 | 1.41004066 |
26 | MST1R | 1.38818385 |
27 | SIK2 | 1.37651152 |
28 | LATS1 | 1.36195852 |
29 | CDK5 | 1.31992691 |
30 | UHMK1 | 1.30981220 |
31 | MAP3K6 | 1.27835460 |
32 | WNK1 | 1.26506679 |
33 | PINK1 | 1.24399640 |
34 | PLK2 | 1.21761392 |
35 | PHKG2 | 1.21687854 |
36 | PHKG1 | 1.21687854 |
37 | STK38L | 1.20990900 |
38 | CAMKK1 | 1.13284448 |
39 | PBK | 1.08740642 |
40 | ERBB3 | 1.03629193 |
41 | PDGFRA | 1.02598265 |
42 | FGR | 1.02513968 |
43 | MAP3K2 | 0.98449896 |
44 | RET | 0.98353927 |
45 | ALK | 0.97044429 |
46 | MKNK2 | 0.95481743 |
47 | DAPK1 | 0.92526128 |
48 | ERBB4 | 0.92236139 |
49 | PAK3 | 0.91269070 |
50 | CSNK1G2 | 0.91077187 |
51 | CAMK2A | 0.91023902 |
52 | BRD4 | 0.90911917 |
53 | SGK223 | 0.90752530 |
54 | SGK494 | 0.90752530 |
55 | TSSK6 | 0.89936997 |
56 | RIPK4 | 0.87760512 |
57 | FGFR2 | 0.87579797 |
58 | PRKCG | 0.87159111 |
59 | SGK2 | 0.86722012 |
60 | TNIK | 0.85685769 |
61 | MARK2 | 0.84915320 |
62 | TAOK1 | 0.84675619 |
63 | SGK1 | 0.84664733 |
64 | PRPF4B | 0.83366557 |
65 | CDC42BPA | 0.82564898 |
66 | DMPK | 0.81990139 |
67 | PKN2 | 0.81740025 |
68 | FES | 0.81449885 |
69 | SGK3 | 0.80449167 |
70 | FER | 0.80061957 |
71 | STK11 | 0.78519167 |
72 | CAMK2G | 0.75400300 |
73 | GRK5 | 0.75051062 |
74 | PRKCH | 0.73722586 |
75 | CDK14 | 0.72948896 |
76 | CDK18 | 0.71845743 |
77 | CDK15 | 0.71662965 |
78 | EPHA2 | 0.68710819 |
79 | PAK2 | 0.66825041 |
80 | CAMK1D | 0.66651950 |
81 | CAMK2B | 0.66231048 |
82 | STK39 | 0.65520376 |
83 | TTN | 0.65283386 |
84 | CAMK2D | 0.64852437 |
85 | TGFBR1 | 0.64705764 |
86 | AKT3 | 0.63611042 |
87 | PDGFRB | 0.63213191 |
88 | DYRK1A | 0.62327608 |
89 | MAP3K12 | 0.62079919 |
90 | BCR | 0.62041330 |
91 | WNK3 | 0.61351989 |
92 | CDK11A | 0.60209338 |
93 | MAPK10 | 0.59846115 |
94 | RPS6KA3 | 0.58974805 |
95 | PRKCZ | 0.58178934 |
96 | TAF1 | 0.57934609 |
97 | LMTK2 | 0.56724284 |
98 | NEK6 | 0.56361041 |
99 | DYRK2 | 0.55266991 |
100 | PRKD2 | 0.54857777 |
101 | CAMK1 | 0.54801951 |
102 | MTOR | 0.54414781 |
103 | RIPK1 | 0.53791830 |
104 | LIMK1 | 0.52161907 |
105 | CDK12 | 0.51287672 |
106 | EPHB2 | 0.51231815 |
107 | PKN1 | 0.50225881 |
108 | PTK2B | 0.49972915 |
109 | BMPR1B | 0.49206386 |
110 | TESK1 | 0.48778465 |
111 | ARAF | 0.48303156 |
112 | ROCK2 | 0.47307221 |
113 | CSNK1E | 0.44377072 |
114 | BMX | 0.44264401 |
115 | PTK2 | 0.43186345 |
116 | PRKCE | 0.42857373 |
117 | SCYL2 | 0.42800732 |
118 | CSNK1A1L | 0.42747639 |
119 | ROCK1 | 0.42731105 |
120 | WEE1 | 0.42359522 |
121 | CDK3 | 0.41679654 |
122 | MKNK1 | 0.41323062 |
123 | TTK | 0.41233729 |
124 | FYN | 0.41058159 |
125 | PRKAA1 | 0.40310795 |
126 | FGFR1 | 0.39921570 |
127 | PDPK1 | 0.38065403 |
128 | PDK1 | 0.37983060 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nicotine addiction_Homo sapiens_hsa05033 | 3.07377624 |
2 | Long-term potentiation_Homo sapiens_hsa04720 | 2.36127125 |
3 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.33767631 |
4 | GABAergic synapse_Homo sapiens_hsa04727 | 2.28491835 |
5 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.26994575 |
6 | Circadian entrainment_Homo sapiens_hsa04713 | 2.23419591 |
7 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.21940593 |
8 | Olfactory transduction_Homo sapiens_hsa04740 | 2.10610610 |
9 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.04627470 |
10 | Morphine addiction_Homo sapiens_hsa05032 | 2.00744570 |
11 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.96947068 |
12 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.93958559 |
13 | Salivary secretion_Homo sapiens_hsa04970 | 1.85316061 |
14 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.74320996 |
15 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.72598558 |
16 | Long-term depression_Homo sapiens_hsa04730 | 1.66823670 |
17 | Insulin secretion_Homo sapiens_hsa04911 | 1.60125891 |
18 | Renin secretion_Homo sapiens_hsa04924 | 1.59647419 |
19 | Axon guidance_Homo sapiens_hsa04360 | 1.59428441 |
20 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.58422828 |
21 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.56408892 |
22 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.54891691 |
23 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.50296045 |
24 | Gap junction_Homo sapiens_hsa04540 | 1.50109742 |
25 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.49369531 |
26 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.48000123 |
27 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.47114912 |
28 | Taste transduction_Homo sapiens_hsa04742 | 1.45660649 |
29 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.43830796 |
30 | Glioma_Homo sapiens_hsa05214 | 1.41232841 |
31 | Cocaine addiction_Homo sapiens_hsa05030 | 1.38396531 |
32 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.33453026 |
33 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.33239487 |
34 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.28345967 |
35 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.25257450 |
36 | Melanogenesis_Homo sapiens_hsa04916 | 1.22825315 |
37 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.22823185 |
38 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.21501406 |
39 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.20627951 |
40 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.18162672 |
41 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.06367567 |
42 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.05783375 |
43 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.04716990 |
44 | Phototransduction_Homo sapiens_hsa04744 | 1.04323365 |
45 | Prion diseases_Homo sapiens_hsa05020 | 1.03499262 |
46 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.01790468 |
47 | Endometrial cancer_Homo sapiens_hsa05213 | 1.01426187 |
48 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 1.01138381 |
49 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.00958235 |
50 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.99217918 |
51 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.99023727 |
52 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.96786715 |
53 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.96644991 |
54 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.95434577 |
55 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.94822434 |
56 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.94809408 |
57 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.93030150 |
58 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.92245033 |
59 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.87548459 |
60 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.86563646 |
61 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.85557825 |
62 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.85068255 |
63 | Colorectal cancer_Homo sapiens_hsa05210 | 0.83078690 |
64 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.81619789 |
65 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.80875909 |
66 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.80850850 |
67 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.80599996 |
68 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.80494325 |
69 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.78220061 |
70 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.75998204 |
71 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.75373933 |
72 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.74919237 |
73 | Amoebiasis_Homo sapiens_hsa05146 | 0.73163424 |
74 | Circadian rhythm_Homo sapiens_hsa04710 | 0.73159518 |
75 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.72587240 |
76 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.72444605 |
77 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.71682142 |
78 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.71373809 |
79 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.71291805 |
80 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.69675863 |
81 | Adherens junction_Homo sapiens_hsa04520 | 0.69511001 |
82 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.68847300 |
83 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.68621899 |
84 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.67967283 |
85 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.67510885 |
86 | Alcoholism_Homo sapiens_hsa05034 | 0.66121353 |
87 | Tight junction_Homo sapiens_hsa04530 | 0.65573851 |
88 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.65402503 |
89 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.64521864 |
90 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.63801445 |
91 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.63565048 |
92 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.63559907 |
93 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.63352268 |
94 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.62657133 |
95 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.61765270 |
96 | Thyroid cancer_Homo sapiens_hsa05216 | 0.61471746 |
97 | Endocytosis_Homo sapiens_hsa04144 | 0.60520183 |
98 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.59479837 |
99 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.59405833 |
100 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.59114026 |
101 | Pathways in cancer_Homo sapiens_hsa05200 | 0.58982158 |
102 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.58142636 |
103 | Bile secretion_Homo sapiens_hsa04976 | 0.57548268 |
104 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.57531435 |
105 | Focal adhesion_Homo sapiens_hsa04510 | 0.56229485 |
106 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.55940945 |
107 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.55783677 |
108 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.54238479 |
109 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.54170432 |
110 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.52908905 |
111 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.52855167 |
112 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.52750821 |
113 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.52432881 |
114 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.52022159 |
115 | Melanoma_Homo sapiens_hsa05218 | 0.51251595 |
116 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.50745044 |
117 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.50479116 |
118 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.45980008 |
119 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.45935871 |
120 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.44797338 |