CAMSAP3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1desmosome organization (GO:0002934)5.82859230
2pyrimidine nucleobase catabolic process (GO:0006208)5.38310059
3response to pheromone (GO:0019236)4.97545154
4intestinal epithelial cell development (GO:0060576)4.73464749
5nucleobase catabolic process (GO:0046113)4.53419106
6establishment of skin barrier (GO:0061436)4.48214659
7regulation of posttranscriptional gene silencing (GO:0060147)4.43136817
8regulation of gene silencing by miRNA (GO:0060964)4.43136817
9regulation of gene silencing by RNA (GO:0060966)4.43136817
10regulation of water loss via skin (GO:0033561)4.37975170
11regulation of hippo signaling (GO:0035330)4.13248352
12anterior/posterior axis specification, embryo (GO:0008595)4.09042807
13paraxial mesoderm development (GO:0048339)3.88928880
14bundle of His cell to Purkinje myocyte communication (GO:0086069)3.87307722
15hemidesmosome assembly (GO:0031581)3.83553587
16polarized epithelial cell differentiation (GO:0030859)3.63134772
17lung epithelium development (GO:0060428)3.58781228
18regulation of cholesterol biosynthetic process (GO:0045540)3.58485871
19proline metabolic process (GO:0006560)3.56071708
20regulation of mammary gland epithelial cell proliferation (GO:0033599)3.52137853
21establishment of monopolar cell polarity (GO:0061162)3.50880053
22establishment or maintenance of monopolar cell polarity (GO:0061339)3.50880053
23regulation of bile acid biosynthetic process (GO:0070857)3.49690635
24establishment of apical/basal cell polarity (GO:0035089)3.43347243
25layer formation in cerebral cortex (GO:0021819)3.41444753
26proline biosynthetic process (GO:0006561)3.40218709
27intestinal absorption (GO:0050892)3.32661441
28negative regulation of oligodendrocyte differentiation (GO:0048715)3.26663303
29cell migration in hindbrain (GO:0021535)3.26246663
30RNA localization (GO:0006403)3.19347085
31spliceosomal tri-snRNP complex assembly (GO:0000244)3.18655829
32positive regulation of synapse maturation (GO:0090129)3.11889464
33ectoderm development (GO:0007398)3.09450776
34histone H4-K12 acetylation (GO:0043983)3.07924903
35establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)3.07639566
36multicellular organismal water homeostasis (GO:0050891)3.07155076
37pre-miRNA processing (GO:0031054)3.06639879
38intestinal cholesterol absorption (GO:0030299)3.06090203
39keratinization (GO:0031424)3.05245319
40regulation of short-term neuronal synaptic plasticity (GO:0048172)3.04822623
41semaphorin-plexin signaling pathway (GO:0071526)3.03218599
42negative regulation of cell fate commitment (GO:0010454)3.02105085
43interferon-gamma secretion (GO:0072643)3.00878657
44peptidyl-arginine omega-N-methylation (GO:0035247)2.93882981
45stress granule assembly (GO:0034063)2.93234213
46embryonic retina morphogenesis in camera-type eye (GO:0060059)2.93064323
47ventricular cardiac muscle cell action potential (GO:0086005)2.91819829
48very-low-density lipoprotein particle assembly (GO:0034379)2.90941408
49cytoskeletal anchoring at plasma membrane (GO:0007016)2.90203314
50dorsal/ventral axis specification (GO:0009950)2.89802314
51embryonic axis specification (GO:0000578)2.88957012
52dosage compensation (GO:0007549)2.88185842
53regulation of cholesterol metabolic process (GO:0090181)2.87520266
54regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.87171772
55peptidyl-tyrosine autophosphorylation (GO:0038083)2.83228668
56apical protein localization (GO:0045176)2.81208173
57adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.80522745
58synaptic vesicle docking involved in exocytosis (GO:0016081)2.80136884
59molting cycle (GO:0042303)2.79615623
60hair cycle (GO:0042633)2.79615623
61protein carboxylation (GO:0018214)2.77790988
62peptidyl-glutamic acid carboxylation (GO:0017187)2.77790988
63urea cycle (GO:0000050)2.77258317
64planar cell polarity pathway involved in neural tube closure (GO:0090179)2.77043856
65plasma lipoprotein particle assembly (GO:0034377)2.76319208
66protein retention in ER lumen (GO:0006621)2.76097250
67negative regulation of keratinocyte proliferation (GO:0010839)2.74248971
68glutamate secretion (GO:0014047)2.73628932
69positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.73328615
70neuron recognition (GO:0008038)2.73058011
71* cell-cell junction maintenance (GO:0045217)2.72954701
72ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162.72847847
73urea metabolic process (GO:0019627)2.72788670
74dopamine receptor signaling pathway (GO:0007212)2.71554184
75cell communication involved in cardiac conduction (GO:0086065)2.70408126
76vocalization behavior (GO:0071625)2.69806040
77histone arginine methylation (GO:0034969)2.69534415
78nodal signaling pathway (GO:0038092)2.68662253
79water homeostasis (GO:0030104)2.68373707
80regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.66024330
81activation of Rac GTPase activity (GO:0032863)2.65982754
82regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.65944133
83dendritic spine morphogenesis (GO:0060997)2.65445705
84central nervous system projection neuron axonogenesis (GO:0021952)2.65300627
85regulation of synapse maturation (GO:0090128)2.64458868
86proximal/distal pattern formation (GO:0009954)2.64316378
87columnar/cuboidal epithelial cell development (GO:0002066)2.63280049
88keratinocyte differentiation (GO:0030216)2.60779529
89regulation of transcription involved in cell fate commitment (GO:0060850)2.59387785
90phospholipid efflux (GO:0033700)2.59225064
91sodium ion export (GO:0071436)2.58982628
92peptidyl-arginine N-methylation (GO:0035246)2.58604935
93peptidyl-arginine methylation (GO:0018216)2.58604935
94trophectodermal cell differentiation (GO:0001829)2.57565240
95regulation of Wnt signaling pathway involved in heart development (GO:0003307)2.56749151
96cell migration involved in sprouting angiogenesis (GO:0002042)2.56467897
97establishment of tissue polarity (GO:0007164)2.55882587
98establishment of planar polarity (GO:0001736)2.55882587
99negative regulation of cell fate specification (GO:0009996)2.55622250
100trivalent inorganic anion homeostasis (GO:0072506)2.55105993
101phosphate ion homeostasis (GO:0055062)2.55105993
102regulation of epithelial cell proliferation involved in prostate gland development (GO:0060768)2.54839586
103calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)2.54750507
104epoxygenase P450 pathway (GO:0019373)2.54607128
105head development (GO:0060322)2.54447559
106embryonic foregut morphogenesis (GO:0048617)2.54216341
107growth hormone secretion (GO:0030252)2.53723188
108ear development (GO:0043583)2.53320227
109mitochondrion distribution (GO:0048311)2.53036000
110regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.52760092
111notochord development (GO:0030903)2.52350065
112atrioventricular valve morphogenesis (GO:0003181)2.52022576
113dendritic spine organization (GO:0097061)2.51969249
114regulation of translational fidelity (GO:0006450)2.51924049
115mitochondrion transport along microtubule (GO:0047497)2.50387539
116establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.50387539
117hormone catabolic process (GO:0042447)2.49052322
118regulation of cholesterol esterification (GO:0010872)2.47877776
119regulation of clathrin-mediated endocytosis (GO:2000369)2.47279419
120maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.47120256
121regulation of cholesterol homeostasis (GO:2000188)2.46675734
122establishment or maintenance of apical/basal cell polarity (GO:0035088)2.46675426
123establishment or maintenance of bipolar cell polarity (GO:0061245)2.46675426
124glucose 6-phosphate metabolic process (GO:0051156)2.46478736
125ephrin receptor signaling pathway (GO:0048013)2.46209829
126regulation of fatty acid beta-oxidation (GO:0031998)2.46063584
127regulation of chemokine-mediated signaling pathway (GO:0070099)2.45254367
128positive regulation of dendritic spine morphogenesis (GO:0061003)2.44776637
129negative regulation of microtubule polymerization (GO:0031115)2.44428577
130ectodermal placode formation (GO:0060788)2.44348689
131epidermal cell differentiation (GO:0009913)2.43857631
132epithelial cell maturation (GO:0002070)2.43377213
133protein-lipid complex assembly (GO:0065005)2.41832742
134glial cell proliferation (GO:0014009)2.41470979
135renal system process involved in regulation of systemic arterial blood pressure (GO:0003071)2.41324854
136regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)2.41084509
137negative regulation of catenin import into nucleus (GO:0035414)2.39871955
138negative regulation of cholesterol transport (GO:0032375)2.39661579
139negative regulation of sterol transport (GO:0032372)2.39661579
140gastrulation with mouth forming second (GO:0001702)2.38956444
141cerebellar granule cell differentiation (GO:0021707)2.37923449
142sulfur amino acid catabolic process (GO:0000098)2.37720775
143epithelial cell differentiation involved in prostate gland development (GO:0060742)2.37600379
144glutamine family amino acid biosynthetic process (GO:0009084)2.36982019
145sodium ion homeostasis (GO:0055078)2.36973444
146receptor recycling (GO:0001881)2.35501160
147neuronal ion channel clustering (GO:0045161)2.35349920
148collecting duct development (GO:0072044)2.34192686
149regulation of heart rate by cardiac conduction (GO:0086091)2.33523349
150regulation of NFAT protein import into nucleus (GO:0051532)2.33145886
151negative regulation of Notch signaling pathway (GO:0045746)2.32540686
152establishment of mitochondrion localization (GO:0051654)2.32012063
153branching involved in mammary gland duct morphogenesis (GO:0060444)2.31964112
154positive regulation of fatty acid beta-oxidation (GO:0032000)2.31846314
155* cell junction maintenance (GO:0034331)2.30619955
156erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)2.30390876
157L-phenylalanine metabolic process (GO:0006558)2.30390876
158intracellular estrogen receptor signaling pathway (GO:0030520)2.30333365
159negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067)2.30068846
160convergent extension (GO:0060026)2.29292973
161nitrogen cycle metabolic process (GO:0071941)2.29279848
162axonal fasciculation (GO:0007413)2.29172771
163gap junction assembly (GO:0016264)2.27020490
164diacylglycerol metabolic process (GO:0046339)2.25309159
165maternal placenta development (GO:0001893)2.24787145
166high-density lipoprotein particle remodeling (GO:0034375)2.23956284
167asymmetric protein localization (GO:0008105)2.23534374
168renal system process involved in regulation of blood volume (GO:0001977)2.21621677
169positive regulation of hormone metabolic process (GO:0032352)2.20783575
170cellular modified amino acid catabolic process (GO:0042219)2.19285974
171positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.18319152
172negative regulation of fatty acid transport (GO:2000192)2.17420198
173negative regulation of cell size (GO:0045792)2.17303701

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human5.81937883
2SMAD3_22036565_ChIP-Seq_ESCs_Mouse3.11270320
3KLF4_18264089_ChIP-ChIP_MESCs_Mouse3.01665497
4KLF2_18264089_ChIP-ChIP_MESCs_Mouse3.01665497
5KLF5_18264089_ChIP-ChIP_MESCs_Mouse3.01665497
6EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.65663390
7ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.60153314
8THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.57999044
9ZFP281_18757296_ChIP-ChIP_E14_Mouse2.45449404
10STAT6_21828071_ChIP-Seq_BEAS2B_Human2.37318241
11NACC1_18358816_ChIP-ChIP_MESCs_Mouse2.30710068
12ZIC3_20872845_ChIP-ChIP_MESCs_Mouse2.29612201
13ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.28944584
14TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.14967337
15SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.10735160
16ZNF263_19887448_ChIP-Seq_K562_Human2.09538348
17ERG_21242973_ChIP-ChIP_JURKAT_Human2.09173966
18SOX2_18358816_ChIP-ChIP_MESCs_Mouse2.07009996
19POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.04877445
20ESR2_21235772_ChIP-Seq_MCF-7_Human1.92486452
21SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.91603959
22NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.91149848
23TCF3_18692474_ChIP-Seq_MESCs_Mouse1.86334755
24ZFP281_27345836_Chip-Seq_ESCs_Mouse1.82125707
25NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.78360018
26CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.77476998
27SALL1_21062744_ChIP-ChIP_HESCs_Human1.75809163
28NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.74900060
29RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.74394563
30RARG_19884340_ChIP-ChIP_MEFs_Mouse1.72271509
31PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.71740110
32ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.71207530
33TET1_21451524_ChIP-Seq_MESCs_Mouse1.67819132
34NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.67227352
35SMC4_20622854_ChIP-Seq_HELA_Human1.65020850
36KDM2B_26808549_Chip-Seq_K562_Human1.64613108
37KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.60363198
38ESR1_21235772_ChIP-Seq_MCF-7_Human1.60092402
39TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.59257544
40TCF3_18692474_ChIP-Seq_MEFs_Mouse1.59175986
41SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.58076551
42RXR_22158963_ChIP-Seq_LIVER_Mouse1.57790798
43FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.52713319
44CDX2_20551321_ChIP-Seq_CACO-2_Human1.49078613
45SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.47917762
46LXR_22292898_ChIP-Seq_THP-1_Human1.47344660
47KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.47057198
48TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.46878715
49SOX2_27498859_Chip-Seq_STOMACH_Mouse1.46854341
50POU5F1_16518401_ChIP-PET_MESCs_Mouse1.39118536
51ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.39025045
52RNF2_18974828_ChIP-Seq_MESCs_Mouse1.37484091
53EZH2_18974828_ChIP-Seq_MESCs_Mouse1.37484091
54CREB1_26743006_Chip-Seq_LNCaP_Human1.35198724
55SOX9_24532713_ChIP-Seq_HFSC_Mouse1.34735662
56KDM2B_26808549_Chip-Seq_DND41_Human1.34430836
57SA1_27219007_Chip-Seq_ERYTHROID_Human1.34263828
58GATA6_25053715_ChIP-Seq_YYC3_Human1.33614558
59RING1B_27294783_Chip-Seq_NPCs_Mouse1.31777950
60ELK3_25401928_ChIP-Seq_HUVEC_Human1.30958824
61SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.30724599
62GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.29749387
63HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.28979198
64RACK7_27058665_Chip-Seq_MCF-7_Human1.28776051
65CTCF_27219007_Chip-Seq_Bcells_Human1.25563266
66ZNF217_24962896_ChIP-Seq_MCF-7_Human1.25228249
67TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.24582792
68TCF7_22412390_ChIP-Seq_EML_Mouse1.24530255
69RUNX1_27514584_Chip-Seq_MCF-7_Human1.23838171
70RNF2_27304074_Chip-Seq_ESCs_Mouse1.23658939
71RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.22450580
72CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.22036974
73PRDM14_21183938_ChIP-Seq_MESCs_Mouse1.21687989
74SOX2_18555785_ChIP-Seq_MESCs_Mouse1.21248491
75NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.21190960
76EZH2_22144423_ChIP-Seq_EOC_Human1.20634517
77OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.20212866
78TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.20142012
79NANOG_21062744_ChIP-ChIP_HESCs_Human1.19784475
80WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.19040290
81SOX2_18692474_ChIP-Seq_MESCs_Mouse1.19033351
82EZH2_27304074_Chip-Seq_ESCs_Mouse1.18973058
83NANOG_18692474_ChIP-Seq_MESCs_Mouse1.18726560
84ISL1_27105846_Chip-Seq_CPCs_Mouse1.18003028
85MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.17443455
86CTCF_27219007_Chip-Seq_ERYTHROID_Human1.16586792
87SRY_22984422_ChIP-ChIP_TESTIS_Rat1.16320002
88PKCTHETA_26484144_Chip-Seq_BREAST_Human1.15055349
89REST_21632747_ChIP-Seq_MESCs_Mouse1.14719209
90TP53_20018659_ChIP-ChIP_R1E_Mouse1.14096051
91ESR1_20079471_ChIP-ChIP_T-47D_Human1.13636636
92SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.12560709
93AHR_22903824_ChIP-Seq_MCF-7_Human1.12000634
94NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.11918375
95EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.11361363
96* SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.10780344
97ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.10545220
98JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse1.09823222
99MTF2_20144788_ChIP-Seq_MESCs_Mouse1.09691502
100SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.09152151
101DNAJC2_21179169_ChIP-ChIP_NT2_Human1.08677323
102P63_26484246_Chip-Seq_KERATINOCYTES_Human1.08177520
103EZH2_27294783_Chip-Seq_ESCs_Mouse1.06966576
104POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.06783460
105DROSHA_22980978_ChIP-Seq_HELA_Human1.06622253
106STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.06454140
107SUZ12_27294783_Chip-Seq_ESCs_Mouse1.05617650
108TP63_22573176_ChIP-Seq_HFKS_Human1.04986364
109JARID2_20064375_ChIP-Seq_MESCs_Mouse1.03980103
110POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.03702824
111BCOR_27268052_Chip-Seq_Bcells_Human1.03698920
112KLF5_25053715_ChIP-Seq_YYC3_Human1.03651272
113TP63_19390658_ChIP-ChIP_HaCaT_Human1.03459882
114RARA_24833708_ChIP-Seq_LIVER_Mouse1.02987124
115RARB_24833708_ChIP-Seq_LIVER_Mouse1.02764579
116RING1B_27294783_Chip-Seq_ESCs_Mouse1.02571591
117STAT3_19079543_ChIP-ChIP_MESCs_Mouse1.02335732
118SA1_27219007_Chip-Seq_Bcells_Human1.02060947
119P68_20966046_ChIP-Seq_HELA_Human1.01659566
120FOXA2_19822575_ChIP-Seq_HepG2_Human1.01578172
121KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.00937984
122POU5F1_18692474_ChIP-Seq_MESCs_Mouse1.00859133
123E2F1_20622854_ChIP-Seq_HELA_Human0.99442183
124ESR1_15608294_ChIP-ChIP_MCF-7_Human0.99343980
125ATF3_27146783_Chip-Seq_COLON_Human0.98449767
126EED_16625203_ChIP-ChIP_MESCs_Mouse0.98176082
127HIF1A_21447827_ChIP-Seq_MCF-7_Human0.96943850
128JARID2_20075857_ChIP-Seq_MESCs_Mouse0.96028880
129PPARA_22158963_ChIP-Seq_LIVER_Mouse0.95754653
130UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.95126131
131RARB_27405468_Chip-Seq_BRAIN_Mouse0.93587084
132TET1_21490601_ChIP-Seq_MESCs_Mouse0.92417996
133PHF8_20622854_ChIP-Seq_HELA_Human0.92215759
134SOX2_18692474_ChIP-Seq_MEFs_Mouse0.91520191
135MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.91446588
136GATA4_25053715_ChIP-Seq_YYC3_Human0.91258295
137KDM2B_26808549_Chip-Seq_SUP-B15_Human0.91248590
138BMI1_23680149_ChIP-Seq_NPCS_Mouse0.90972057
139KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.90306627
140NANOG_18692474_ChIP-Seq_MEFs_Mouse0.90172913
141KAP1_27257070_Chip-Seq_ESCs_Mouse0.90075882
142NANOG_16518401_ChIP-PET_MESCs_Mouse0.89407792

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010234_abnormal_vibrissa_follicle4.42417013
2MP0002796_impaired_skin_barrier3.55328614
3MP0003123_paternal_imprinting2.95364608
4MP0002653_abnormal_ependyma_morphology2.81310054
5MP0000537_abnormal_urethra_morphology2.77385199
6MP0010030_abnormal_orbit_morphology2.74202546
7MP0004264_abnormal_extraembryonic_tissu2.69599456
8MP0002098_abnormal_vibrissa_morphology2.55750849
9MP0008789_abnormal_olfactory_epithelium2.41894475
10MP0005499_abnormal_olfactory_system2.38019459
11MP0005394_taste/olfaction_phenotype2.38019459
12MP0003283_abnormal_digestive_organ2.35644923
13MP0005501_abnormal_skin_physiology2.32103071
14MP0005409_darkened_coat_color2.30978817
15MP0003705_abnormal_hypodermis_morpholog2.26327281
16MP0000579_abnormal_nail_morphology2.21969165
17MP0003941_abnormal_skin_development2.20252505
18MP0003119_abnormal_digestive_system2.14093025
19MP0003890_abnormal_embryonic-extraembry2.11294325
20MP0001849_ear_inflammation1.93215495
21MP0009780_abnormal_chondrocyte_physiolo1.90684888
22MP0001188_hyperpigmentation1.83750984
23MP0002254_reproductive_system_inflammat1.81214872
24MP0005248_abnormal_Harderian_gland1.80452973
25MP0004858_abnormal_nervous_system1.77155220
26MP0003879_abnormal_hair_cell1.76315493
27MP0001666_abnormal_nutrient_absorption1.74703637
28MP0000778_abnormal_nervous_system1.73749589
29MP0004019_abnormal_vitamin_homeostasis1.72853074
30MP0000566_synostosis1.72133411
31MP0005360_urolithiasis1.71460175
32MP0009379_abnormal_foot_pigmentation1.71096597
33MP0001346_abnormal_lacrimal_gland1.70137994
34MP0002089_abnormal_postnatal_growth/wei1.69933698
35MP0004133_heterotaxia1.61733352
36MP0010352_gastrointestinal_tract_polyps1.57090857
37MP0002249_abnormal_larynx_morphology1.46976762
38MP0005085_abnormal_gallbladder_physiolo1.41984355
39MP0003122_maternal_imprinting1.40654829
40MP0008995_early_reproductive_senescence1.40174477
41MP0002822_catalepsy1.37379194
42MP0005365_abnormal_bile_salt1.37217456
43MP0005423_abnormal_somatic_nervous1.36247050
44MP0003315_abnormal_perineum_morphology1.34706282
45MP0002139_abnormal_hepatobiliary_system1.33029934
46MP0009053_abnormal_anal_canal1.32247477
47MP0004859_abnormal_synaptic_plasticity1.27911235
48MP0001216_abnormal_epidermal_layer1.26424731
49MP0005076_abnormal_cell_differentiation1.26348473
50MP0000467_abnormal_esophagus_morphology1.26169273
51MP0010329_abnormal_lipoprotein_level1.26162571
52MP0003942_abnormal_urinary_system1.25728874
53MP0008004_abnormal_stomach_pH1.25445695
54MP0003011_delayed_dark_adaptation1.24020791
55MP0010678_abnormal_skin_adnexa1.23969275
56MP0001984_abnormal_olfaction1.23914402
57MP0000377_abnormal_hair_follicle1.22325282
58MP0001664_abnormal_digestion1.22063219
59MP0003861_abnormal_nervous_system1.18913139
60MP0003329_amyloid_beta_deposits1.16105569
61MP0003635_abnormal_synaptic_transmissio1.15865241
62MP0005645_abnormal_hypothalamus_physiol1.14619398
63MP0000462_abnormal_digestive_system1.13146441
64MP0002234_abnormal_pharynx_morphology1.11406131
65MP0004270_analgesia1.11349709
66MP0010771_integument_phenotype1.11002016
67MP0005187_abnormal_penis_morphology1.10668866
68MP0006292_abnormal_olfactory_placode1.10344312
69MP0002734_abnormal_mechanical_nocicepti1.10011672
70MP0000762_abnormal_tongue_morphology1.09300650
71MP0008961_abnormal_basal_metabolism1.09184825
72MP0002084_abnormal_developmental_patter1.08590376
73MP0000538_abnormal_urinary_bladder1.06761167
74MP0009672_abnormal_birth_weight1.05411338
75MP0000516_abnormal_urinary_system1.04814910
76MP0005367_renal/urinary_system_phenotyp1.04814910
77MP0002184_abnormal_innervation1.03803294
78MP0000647_abnormal_sebaceous_gland1.02807380
79MP0003115_abnormal_respiratory_system1.02092483
80MP0004885_abnormal_endolymph1.01539367
81MP0001502_abnormal_circadian_rhythm0.99286723
82MP0000427_abnormal_hair_cycle0.97089294
83MP0005646_abnormal_pituitary_gland0.96806559
84MP0008875_abnormal_xenobiotic_pharmacok0.96042793
85MP0002697_abnormal_eye_size0.95381359
86MP0009840_abnormal_foam_cell0.93697390
87MP0003453_abnormal_keratinocyte_physiol0.92845564
88MP0000955_abnormal_spinal_cord0.92059655
89MP0003787_abnormal_imprinting0.91981754
90MP0005670_abnormal_white_adipose0.91448180
91MP0000678_abnormal_parathyroid_gland0.90530105
92MP0000470_abnormal_stomach_morphology0.90181769
93MP0000049_abnormal_middle_ear0.88121197
94MP0000534_abnormal_ureter_morphology0.87443435
95MP0003183_abnormal_peptide_metabolism0.86919124
96MP0004185_abnormal_adipocyte_glucose0.86303924
97MP0000631_abnormal_neuroendocrine_gland0.85691909
98MP0002060_abnormal_skin_morphology0.85365980
99MP0003252_abnormal_bile_duct0.84950220
100MP0005275_abnormal_skin_tensile0.84590294
101MP0004782_abnormal_surfactant_physiolog0.84571765
102MP0003878_abnormal_ear_physiology0.84080624
103MP0005377_hearing/vestibular/ear_phenot0.84080624
104MP0003121_genomic_imprinting0.83278341
105MP0002557_abnormal_social/conspecific_i0.82790070
106MP0002085_abnormal_embryonic_tissue0.82652106
107MP0003868_abnormal_feces_composition0.82046971
108MP0001765_abnormal_ion_homeostasis0.80172047
109MP0004197_abnormal_fetal_growth/weight/0.79998486
110MP0005666_abnormal_adipose_tissue0.79017374
111MP0004811_abnormal_neuron_physiology0.78810814
112MP0000613_abnormal_salivary_gland0.77015355
113MP0002064_seizures0.76652300
114MP0001348_abnormal_lacrimal_gland0.76443989
115MP0003935_abnormal_craniofacial_develop0.74325726
116MP0002152_abnormal_brain_morphology0.73812507
117MP0004742_abnormal_vestibular_system0.73750586
118MP0003755_abnormal_palate_morphology0.73422389
119MP0002111_abnormal_tail_morphology0.73245047
120MP0003880_abnormal_central_pattern0.72792292
121MP0000003_abnormal_adipose_tissue0.72764274
122MP0002572_abnormal_emotion/affect_behav0.72714731
123MP0000383_abnormal_hair_follicle0.72568005
124MP0002909_abnormal_adrenal_gland0.72488253
125MP0004043_abnormal_pH_regulation0.72253395
126MP0002233_abnormal_nose_morphology0.71645037
127MP0010386_abnormal_urinary_bladder0.70362826
128MP0002277_abnormal_respiratory_mucosa0.70337667
129MP0001968_abnormal_touch/_nociception0.69504778
130MP0005451_abnormal_body_composition0.69333937
131MP0003938_abnormal_ear_development0.68652919
132MP0002063_abnormal_learning/memory/cond0.68624577
133MP0002118_abnormal_lipid_homeostasis0.65593353
134MP0004381_abnormal_hair_follicle0.64954050
135MP0005375_adipose_tissue_phenotype0.63436096
136MP0009931_abnormal_skin_appearance0.62805480
137MP0000477_abnormal_intestine_morphology0.61790566
138MP0002882_abnormal_neuron_morphology0.61195302
139MP0002116_abnormal_craniofacial_bone0.60454510

Predicted human phenotypes

RankGene SetZ-score
1Deep venous thrombosis (HP:0002625)4.08996704
2Ependymoma (HP:0002888)3.88739159
3Pili torti (HP:0003777)3.78121347
4Myokymia (HP:0002411)3.45136866
5Right ventricular cardiomyopathy (HP:0011663)3.43725054
6Abnormality of the astrocytes (HP:0100707)3.39100209
7Astrocytoma (HP:0009592)3.39100209
8Bronchomalacia (HP:0002780)3.36592616
9Hypotrichosis (HP:0001006)3.27476278
10Woolly hair (HP:0002224)3.23905405
11Shawl scrotum (HP:0000049)3.16627064
12Amyotrophic lateral sclerosis (HP:0007354)3.03812982
13Fragile nails (HP:0001808)3.00389542
14Septate vagina (HP:0001153)2.98112058
15Plantar hyperkeratosis (HP:0007556)2.96418330
16Germ cell neoplasia (HP:0100728)2.94588521
17Abnormality of the lower motor neuron (HP:0002366)2.89389134
18Flat acetabular roof (HP:0003180)2.88318145
19Milia (HP:0001056)2.81130064
20Abnormality of monocarboxylic acid metabolism (HP:0010996)2.79745096
21Obstructive sleep apnea (HP:0002870)2.79074446
22Hemorrhage of the eye (HP:0011885)2.78672838
23Renovascular hypertension (HP:0100817)2.70378567
24Abnormality of the aortic arch (HP:0012303)2.55793446
25Failure to thrive in infancy (HP:0001531)2.54761647
26Aplasia involving bones of the extremities (HP:0009825)2.54336739
27Aplasia involving bones of the upper limbs (HP:0009823)2.54336739
28Aplasia of the phalanges of the hand (HP:0009802)2.54336739
29Thin bony cortex (HP:0002753)2.49903977
30Onycholysis (HP:0001806)2.49702381
31Hand muscle atrophy (HP:0009130)2.45884837
32Hepatoblastoma (HP:0002884)2.45444870
33Polyphagia (HP:0002591)2.43940368
34Partial duplication of thumb phalanx (HP:0009944)2.39444370
35Abnormality of glutamine family amino acid metabolism (HP:0010902)2.36498984
36Lip pit (HP:0100267)2.34897704
37Curly hair (HP:0002212)2.34277486
38Ventricular fibrillation (HP:0001663)2.32815044
39Abnormal hair laboratory examination (HP:0003328)2.32237044
40Bifid scrotum (HP:0000048)2.29863731
41Elfin facies (HP:0004428)2.28142509
42Palmoplantar hyperkeratosis (HP:0000972)2.27198762
43Hyperacusis (HP:0010780)2.26488075
44Prolonged partial thromboplastin time (HP:0003645)2.26204328
45Glioma (HP:0009733)2.24309889
46Palmar hyperkeratosis (HP:0010765)2.22277196
47Abnormality of the labia minora (HP:0012880)2.21673048
48Abdominal situs inversus (HP:0003363)2.21635048
49Abnormality of abdominal situs (HP:0011620)2.21635048
50Abnormality of nail color (HP:0100643)2.16935573
51Sparse scalp hair (HP:0002209)2.16121188
52Widely patent fontanelles and sutures (HP:0004492)2.15556189
53Akinesia (HP:0002304)2.11171699
54Hypoplastic labia majora (HP:0000059)2.10086469
55Sleep apnea (HP:0010535)2.09029356
56Abnormality of permanent molar morphology (HP:0011071)2.06307348
57Abnormality of the dental root (HP:0006486)2.06307348
58Taurodontia (HP:0000679)2.06307348
59Gout (HP:0001997)2.05117890
60Xanthomatosis (HP:0000991)2.04925546
61Colon cancer (HP:0003003)2.04544601
62Progressive sensorineural hearing impairment (HP:0000408)2.02257609
63Abnormality of aromatic amino acid family metabolism (HP:0004338)2.01810495
64Short humerus (HP:0005792)2.01313246
65Renal duplication (HP:0000075)1.99532144
66Abnormality of the distal phalanx of the thumb (HP:0009617)1.99451284
67Hyperparathyroidism (HP:0000843)1.99326979
68Choanal stenosis (HP:0000452)1.98409880
69Insomnia (HP:0100785)1.97263732
70Neonatal death (HP:0003811)1.97157941
71Asymmetry of the thorax (HP:0001555)1.97019957
72Ankyloglossia (HP:0010296)1.95643486
73Ankle clonus (HP:0011448)1.95207288
74Abnormality of the salivary glands (HP:0010286)1.94857792
75Neoplasm of the heart (HP:0100544)1.94766154
76Malnutrition (HP:0004395)1.93902693
77Abnormal tarsal ossification (HP:0008369)1.92852008
78Hyperphosphatemia (HP:0002905)1.90176165
79High anterior hairline (HP:0009890)1.89212046
80Hypohidrosis (HP:0000966)1.88501217
81Alacrima (HP:0000522)1.88227148
82Hypercholesterolemia (HP:0003124)1.87646656
83Partial duplication of the phalanx of hand (HP:0009999)1.86860041
84Neonatal onset (HP:0003623)1.85339729
85Neoplasm of the oral cavity (HP:0100649)1.84399056
86Abnormality of the gastric mucosa (HP:0004295)1.83884420
87Long palpebral fissure (HP:0000637)1.82896937
88Broad face (HP:0000283)1.82848355
89Atrophy/Degeneration involving motor neurons (HP:0007373)1.82415363
90Labial hypoplasia (HP:0000066)1.82352941
91Hamartoma of the eye (HP:0010568)1.82352523
92Abnormality of the lacrimal duct (HP:0011481)1.81961554
93Hyperuricemia (HP:0002149)1.81849878
94Increased purine levels (HP:0004368)1.81849878
95Turricephaly (HP:0000262)1.81783124
96Stridor (HP:0010307)1.81234782
97Abnormality of molar morphology (HP:0011070)1.80736651
98Abnormality of molar (HP:0011077)1.80736651
99Gastrointestinal carcinoma (HP:0002672)1.80643912
100Malignant gastrointestinal tract tumors (HP:0006749)1.80643912
101Abnormality of the labia majora (HP:0012881)1.80322214
102Bilateral microphthalmos (HP:0007633)1.79773008
103Anal stenosis (HP:0002025)1.79437124
104Hypobetalipoproteinemia (HP:0003563)1.78744261
105Hypoplasia of the uterus (HP:0000013)1.78737075
106Testicular neoplasm (HP:0010788)1.78727570
107Aplasia/hypoplasia of the humerus (HP:0006507)1.78460567
108Split foot (HP:0001839)1.78425255
109Congenital ichthyosiform erythroderma (HP:0007431)1.78293568
110Abnormality of the dental pulp (HP:0006479)1.78170914
111Ulnar bowing (HP:0003031)1.77684925
112Nail dystrophy (HP:0008404)1.77246111
113Hyperactive renin-angiotensin system (HP:0000841)1.76818193
114Abdominal distention (HP:0003270)1.76509861
115Abnormality of the musculature of the hand (HP:0001421)1.75712062
116Amelogenesis imperfecta (HP:0000705)1.75677520
117Cortical dysplasia (HP:0002539)1.75654470
118Angiofibromas (HP:0010615)1.75287119
119Adenoma sebaceum (HP:0009720)1.75287119
120Medulloblastoma (HP:0002885)1.75197585
121Hyperglycinuria (HP:0003108)1.74584005
122Absent eyelashes (HP:0000561)1.73984272
123Abnormality of carpal bone ossification (HP:0006257)1.73293530
124Hamartoma (HP:0010566)1.72054329
125Cerebral inclusion bodies (HP:0100314)1.71518217
126Pseudobulbar signs (HP:0002200)1.71031190
127Growth hormone excess (HP:0000845)1.69422395
128Vaginal fistula (HP:0004320)1.69215800
129Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.68725511
130Hypoplasia of dental enamel (HP:0006297)1.68631825
131Hyperthyroidism (HP:0000836)1.68443094
132Thickened helices (HP:0000391)1.68278275
133Esophageal atresia (HP:0002032)1.67674494
134Focal segmental glomerulosclerosis (HP:0000097)1.67481363
135Pterygium (HP:0001059)1.67250816
136Visceral angiomatosis (HP:0100761)1.67143865
137Tracheal stenosis (HP:0002777)1.66722274
138Overriding aorta (HP:0002623)1.66405703
139Distal upper limb amyotrophy (HP:0007149)1.65995273
140Upper limb amyotrophy (HP:0009129)1.65995273
141Subcapsular cataract (HP:0000523)1.65679851
142Precocious puberty (HP:0000826)1.65062497
143Neurofibrillary tangles (HP:0002185)1.64954350
144Anophthalmia (HP:0000528)1.63584756
145Urinary bladder sphincter dysfunction (HP:0002839)1.63441430
146Transposition of the great arteries (HP:0001669)1.61266281
147Abnormal connection of the cardiac segments (HP:0011545)1.61266281
148Abnormal ventriculo-arterial connection (HP:0011563)1.61266281
149Wide cranial sutures (HP:0010537)1.61023378
150Abnormal blistering of the skin (HP:0008066)1.60744650
151Neoplasm of striated muscle (HP:0009728)1.60588587
152Abnormality of the labia (HP:0000058)1.59948315
153Delayed epiphyseal ossification (HP:0002663)1.59920427
154Megalocornea (HP:0000485)1.59909486
155Heterotopia (HP:0002282)1.59822967
156Advanced eruption of teeth (HP:0006288)1.59721039
157Abnormal pancreas size (HP:0012094)1.58557254
158Complement deficiency (HP:0004431)1.58530790
159Alopecia of scalp (HP:0002293)1.58357484
160Biliary tract neoplasm (HP:0100574)1.58277795
161Bicornuate uterus (HP:0000813)1.57872100
162Abnormality of proline metabolism (HP:0010907)1.57408061
163Hydroxyprolinuria (HP:0003080)1.57408061
164Nasolacrimal duct obstruction (HP:0000579)1.56969083
165Hypercalciuria (HP:0002150)1.56745164
166Lymphangioma (HP:0100764)1.56109192
167Abnormality of the diencephalon (HP:0010662)1.55920648
168Hypoplastic female external genitalia (HP:0012815)1.55378640
169Progressive hearing impairment (HP:0001730)1.55339691
170Symptomatic seizures (HP:0011145)1.53901578
171Acanthosis nigricans (HP:0000956)1.53707761

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.35755933
2MARK13.65276902
3CDK123.53096329
4EPHA23.26917377
5MAP3K93.08150324
6SMG12.97120008
7ICK2.91742940
8ERN12.88353975
9FGFR42.50268042
10AKT32.37586885
11EPHB22.33356609
12MAP3K22.22020882
13LATS22.14816719
14LATS12.01824592
15RPS6KB21.86273314
16EEF2K1.80022195
17FER1.68276930
18MAP3K101.66837380
19DYRK21.66233648
20PTK61.66187938
21RIPK11.54051469
22TYRO31.51200660
23MAP3K41.50643378
24MAP2K21.49435541
25MST1R1.49265043
26BRD41.48149494
27KSR11.47474101
28MAPKAPK31.46948866
29CAMK1D1.44930387
30WNK31.41720408
31PRKCI1.38945770
32MAP2K61.36781463
33NTRK21.36037662
34ERBB21.34423828
35MINK11.32807120
36PAK61.26715061
37UHMK11.18376743
38BCKDK1.12720989
39CASK1.10995461
40TAOK11.09512261
41STK38L1.07848196
42PTK21.07192597
43PHKG21.06878416
44PHKG11.06878416
45WNK41.05504459
46IRAK31.01925321
47CAMK1G1.00895511
48STK380.99211048
49MTOR0.97735022
50MST40.95893751
51NEK10.93645082
52SIK10.93380072
53MAP2K40.93311192
54CHEK20.92118093
55INSRR0.91224100
56FRK0.90104314
57TTK0.89439038
58MAP3K60.87938334
59SGK4940.87688111
60SGK2230.87688111
61DYRK1B0.87379227
62ERBB40.86613670
63CAMKK10.86285254
64BCR0.83346788
65DAPK20.82727197
66NTRK30.82499402
67PRPF4B0.81237315
68ERBB30.80607005
69MAP3K70.79059927
70KSR20.78179342
71FGFR30.76747578
72MAP3K30.73026379
73NME10.72345741
74PRKCZ0.71932476
75MET0.71922773
76PRKD30.71626937
77PDPK10.71369300
78TESK10.71366687
79PRKD20.69173358
80SCYL20.67450634
81FGFR10.66571046
82MARK20.63868818
83CSNK1E0.63146325
84AKT20.63018414
85PRKAA10.61896748
86RPS6KA20.61203899
87BRAF0.60607226
88PRKG20.60254562
89MATK0.59515836
90CDK70.58572360
91SGK30.57647794
92DDR20.56277957
93RET0.55915242
94PDGFRA0.55426815
95RPS6KA10.54873008
96LMTK20.53872866
97SIK30.53189259
98PAK30.52933073
99DYRK1A0.52730897
100IRAK20.52642036
101MAP3K10.52516261
102ACVR1B0.52286517
103MAPK130.51905457
104MAP2K10.50109297
105PKN20.50053764
106NTRK10.49012884
107SIK20.48540829
108MAPK80.48096520
109AURKA0.46665039
110EPHB10.45601502
111MUSK0.45264475
112CDK150.43831625
113PAK40.43596786
114CDC42BPA0.43059081
115DMPK0.42800151
116CDK11A0.42399084
117EPHA40.42085006
118FGFR20.41936773
119CDK50.41922169
120RPS6KL10.41851988
121RPS6KC10.41851988
122CSNK1D0.41519184
123STK110.41506406
124TNK20.41433755
125BMX0.41038259
126MAPK150.40758146
127ARAF0.40695140
128NEK60.40270236
129PRKAA20.40127396
130HIPK20.39918495
131CDK180.39325550
132MAPK90.38678831
133MELK0.37849065
134GSK3B0.37502441
135DAPK10.36483992
136CDK20.35097975
137RPS6KB10.35011078
138MAP3K110.33904959

Predicted pathways (KEGG)

RankGene SetZ-score
1Fat digestion and absorption_Homo sapiens_hsa049752.59059089
2Basal cell carcinoma_Homo sapiens_hsa052172.20218681
3Hippo signaling pathway_Homo sapiens_hsa043902.12281186
4Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045502.05161152
5Maturity onset diabetes of the young_Homo sapiens_hsa049502.04977158
6Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.03152168
7Cyanoamino acid metabolism_Homo sapiens_hsa004602.02541972
8Phenylalanine metabolism_Homo sapiens_hsa003601.85929562
9Histidine metabolism_Homo sapiens_hsa003401.85563316
10Endometrial cancer_Homo sapiens_hsa052131.80971917
11Axon guidance_Homo sapiens_hsa043601.67030600
12Tight junction_Homo sapiens_hsa045301.65635203
13Bile secretion_Homo sapiens_hsa049761.64483881
14Vitamin B6 metabolism_Homo sapiens_hsa007501.62066030
15Synaptic vesicle cycle_Homo sapiens_hsa047211.52295702
16Arginine and proline metabolism_Homo sapiens_hsa003301.48877734
17mTOR signaling pathway_Homo sapiens_hsa041501.47112515
18Lysine degradation_Homo sapiens_hsa003101.45234364
19Adherens junction_Homo sapiens_hsa045201.44813949
20Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.42271176
21Hedgehog signaling pathway_Homo sapiens_hsa043401.39615550
22Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.36878662
23Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.35294227
24Fructose and mannose metabolism_Homo sapiens_hsa000511.34919797
25Mineral absorption_Homo sapiens_hsa049781.34227235
26Arginine biosynthesis_Homo sapiens_hsa002201.31866993
27Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.30215318
28Steroid biosynthesis_Homo sapiens_hsa001001.26236179
29Nicotine addiction_Homo sapiens_hsa050331.25595902
30Caffeine metabolism_Homo sapiens_hsa002321.25191739
31Notch signaling pathway_Homo sapiens_hsa043301.24069756
32Protein digestion and absorption_Homo sapiens_hsa049741.23634751
332-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.17695238
34Fatty acid biosynthesis_Homo sapiens_hsa000611.15117693
35Tryptophan metabolism_Homo sapiens_hsa003801.14186858
36Pancreatic secretion_Homo sapiens_hsa049721.13385074
37Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.11553357
38Wnt signaling pathway_Homo sapiens_hsa043101.11141459
39Nitrogen metabolism_Homo sapiens_hsa009101.10682352
40Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.08674974
41alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.07299890
42Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.04560858
43PPAR signaling pathway_Homo sapiens_hsa033201.03838677
44Butanoate metabolism_Homo sapiens_hsa006501.03253208
45Gap junction_Homo sapiens_hsa045401.00119869
46Melanogenesis_Homo sapiens_hsa049160.96924688
47Insulin secretion_Homo sapiens_hsa049110.95588124
48Thyroid hormone signaling pathway_Homo sapiens_hsa049190.95095225
49Fatty acid metabolism_Homo sapiens_hsa012120.94856200
50Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.94796824
51Tyrosine metabolism_Homo sapiens_hsa003500.94662570
52Aldosterone synthesis and secretion_Homo sapiens_hsa049250.94028074
53Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.93816076
54Glycerolipid metabolism_Homo sapiens_hsa005610.93131568
55Cocaine addiction_Homo sapiens_hsa050300.93129933
56Amphetamine addiction_Homo sapiens_hsa050310.91755317
57Glucagon signaling pathway_Homo sapiens_hsa049220.91450988
58ErbB signaling pathway_Homo sapiens_hsa040120.91235139
59AMPK signaling pathway_Homo sapiens_hsa041520.90226534
60Pentose and glucuronate interconversions_Homo sapiens_hsa000400.89280797
61Complement and coagulation cascades_Homo sapiens_hsa046100.88968456
62Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.88058807
63Longevity regulating pathway - mammal_Homo sapiens_hsa042110.87235923
64Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.86776606
65Bladder cancer_Homo sapiens_hsa052190.84838271
66Galactose metabolism_Homo sapiens_hsa000520.83915400
67Steroid hormone biosynthesis_Homo sapiens_hsa001400.83405517
68Gastric acid secretion_Homo sapiens_hsa049710.82665798
69Carbohydrate digestion and absorption_Homo sapiens_hsa049730.79935366
70Thyroid hormone synthesis_Homo sapiens_hsa049180.78835037
71Linoleic acid metabolism_Homo sapiens_hsa005910.77869139
72Sphingolipid metabolism_Homo sapiens_hsa006000.76803619
73Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.76439794
74Colorectal cancer_Homo sapiens_hsa052100.75069330
75Prion diseases_Homo sapiens_hsa050200.75053684
76Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.74238871
77Choline metabolism in cancer_Homo sapiens_hsa052310.73707821
78Vibrio cholerae infection_Homo sapiens_hsa051100.73327032
79ABC transporters_Homo sapiens_hsa020100.72938430
80Drug metabolism - other enzymes_Homo sapiens_hsa009830.72623389
81Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.71878626
82Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.71622741
83Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.71565248
84GnRH signaling pathway_Homo sapiens_hsa049120.71466352
85Central carbon metabolism in cancer_Homo sapiens_hsa052300.71156766
86Fatty acid degradation_Homo sapiens_hsa000710.70867562
87Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.69984831
88Sulfur metabolism_Homo sapiens_hsa009200.69912258
89Type II diabetes mellitus_Homo sapiens_hsa049300.69717266
90Starch and sucrose metabolism_Homo sapiens_hsa005000.69647684
91Vitamin digestion and absorption_Homo sapiens_hsa049770.69524490
92Selenocompound metabolism_Homo sapiens_hsa004500.68545307
93Sulfur relay system_Homo sapiens_hsa041220.68240001
94mRNA surveillance pathway_Homo sapiens_hsa030150.67427279
95Estrogen signaling pathway_Homo sapiens_hsa049150.66545368
96Salivary secretion_Homo sapiens_hsa049700.66225513
97Thyroid cancer_Homo sapiens_hsa052160.65597985
98Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.65466283
99Cholinergic synapse_Homo sapiens_hsa047250.62900124
100Glutamatergic synapse_Homo sapiens_hsa047240.62672771
101Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.62172623
102Dopaminergic synapse_Homo sapiens_hsa047280.62165095
103GABAergic synapse_Homo sapiens_hsa047270.62061004
104Biosynthesis of amino acids_Homo sapiens_hsa012300.61747577
105Phosphatidylinositol signaling system_Homo sapiens_hsa040700.61632640
106VEGF signaling pathway_Homo sapiens_hsa043700.61501207
107Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.60691685
108Circadian entrainment_Homo sapiens_hsa047130.60277335
109Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.59686056
110Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.59650003
111Retinol metabolism_Homo sapiens_hsa008300.59134884
112Glycerophospholipid metabolism_Homo sapiens_hsa005640.59054466
113Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.59031280
114Insulin resistance_Homo sapiens_hsa049310.58884952
115Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.58771129
116Insulin signaling pathway_Homo sapiens_hsa049100.58197678
117Ovarian steroidogenesis_Homo sapiens_hsa049130.57089654
118Long-term potentiation_Homo sapiens_hsa047200.56974620
119Renin-angiotensin system_Homo sapiens_hsa046140.56725703
120N-Glycan biosynthesis_Homo sapiens_hsa005100.56611272
121Oocyte meiosis_Homo sapiens_hsa041140.55510588
122Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.55314447
123TGF-beta signaling pathway_Homo sapiens_hsa043500.55095262
124Chemical carcinogenesis_Homo sapiens_hsa052040.54420290
125beta-Alanine metabolism_Homo sapiens_hsa004100.54043086
126MicroRNAs in cancer_Homo sapiens_hsa052060.53850269
127Pyruvate metabolism_Homo sapiens_hsa006200.53030601
128Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.51815943
129Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.51108982
130Inositol phosphate metabolism_Homo sapiens_hsa005620.51010750
131Long-term depression_Homo sapiens_hsa047300.50497691
132Glioma_Homo sapiens_hsa052140.49462745
133Primary bile acid biosynthesis_Homo sapiens_hsa001200.48934405

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