CAMTA1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene contains a CG1 DNA-binding domain, a transcription factor immunoglobulin domain, ankyrin repeats, and calmodulin-binding IQ motifs. The encoded protein is thought to be a transcription factor and may be a tumor suppressor. However, a translocation event is sometimes observed between this gene and the WWTR1 gene, with the resulting WWTR1-CAMTA1 oncoprotein leading to epithelioid hemangioendothelioma, a malignant vascular cancer. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)5.85863537
2vocalization behavior (GO:0071625)5.36879536
3synaptic vesicle maturation (GO:0016188)5.30789327
4positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.29277499
5locomotory exploration behavior (GO:0035641)5.24986768
6positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.20169899
7synaptic vesicle exocytosis (GO:0016079)5.14339939
8regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.05871635
9glutamate secretion (GO:0014047)4.85973886
10regulation of synaptic vesicle exocytosis (GO:2000300)4.78224237
11ionotropic glutamate receptor signaling pathway (GO:0035235)4.77296147
12neuron cell-cell adhesion (GO:0007158)4.77286741
13regulation of glutamate receptor signaling pathway (GO:1900449)4.71939357
14protein localization to synapse (GO:0035418)4.69005072
15neuronal action potential propagation (GO:0019227)4.58495324
16neurotransmitter secretion (GO:0007269)4.40322465
17glutamate receptor signaling pathway (GO:0007215)4.32853154
18regulation of synaptic vesicle transport (GO:1902803)4.30016582
19synaptic vesicle docking involved in exocytosis (GO:0016081)4.28495817
20exploration behavior (GO:0035640)4.26126170
21pyrimidine nucleobase catabolic process (GO:0006208)4.16516353
22regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.15764340
23synaptic transmission, glutamatergic (GO:0035249)4.13619339
24gamma-aminobutyric acid transport (GO:0015812)4.07378377
25regulation of long-term neuronal synaptic plasticity (GO:0048169)4.05426392
26layer formation in cerebral cortex (GO:0021819)4.03560490
27regulation of neuronal synaptic plasticity (GO:0048168)4.01600801
28neuron-neuron synaptic transmission (GO:0007270)3.98609739
29membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.92157070
30regulation of synapse structural plasticity (GO:0051823)3.86927197
31neuron recognition (GO:0008038)3.80535738
32dendritic spine morphogenesis (GO:0060997)3.78982027
33cellular potassium ion homeostasis (GO:0030007)3.78578590
34positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.78402819
35proline transport (GO:0015824)3.76283971
36long-term memory (GO:0007616)3.74248867
37neurotransmitter-gated ion channel clustering (GO:0072578)3.73022306
38mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.70128769
39regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.69794552
40regulation of excitatory postsynaptic membrane potential (GO:0060079)3.68599680
41neurotransmitter transport (GO:0006836)3.67659483
42protein neddylation (GO:0045116)3.63841202
43cerebellar Purkinje cell differentiation (GO:0021702)3.61479176
44cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.60187733
45gamma-aminobutyric acid signaling pathway (GO:0007214)3.57330288
46mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.56592393
47regulation of postsynaptic membrane potential (GO:0060078)3.56586000
48transmission of nerve impulse (GO:0019226)3.52828080
49positive regulation of membrane potential (GO:0045838)3.50019564
50neuromuscular process controlling posture (GO:0050884)3.45815526
51positive regulation of synapse maturation (GO:0090129)3.44299148
52axonal fasciculation (GO:0007413)3.43997562
53sodium ion export (GO:0071436)3.42413838
54negative regulation of synaptic transmission, GABAergic (GO:0032229)3.41941085
55G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.39861746
56nucleobase catabolic process (GO:0046113)3.39731559
57postsynaptic membrane organization (GO:0001941)3.38479751
58cell communication by electrical coupling (GO:0010644)3.38328239
59synaptic vesicle endocytosis (GO:0048488)3.37937347
60membrane depolarization during action potential (GO:0086010)3.35836764
61activation of protein kinase A activity (GO:0034199)3.35799343
62positive regulation of synaptic transmission, GABAergic (GO:0032230)3.34792157
63chaperone-mediated protein transport (GO:0072321)3.34071140
64regulation of neurotransmitter levels (GO:0001505)3.33986501
65regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.32384109
66central nervous system myelination (GO:0022010)3.31721979
67axon ensheathment in central nervous system (GO:0032291)3.31721979
68regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.31677981
69behavioral response to nicotine (GO:0035095)3.31067113
70mechanosensory behavior (GO:0007638)3.29973700
71regulation of neurotransmitter secretion (GO:0046928)3.29679370
72presynaptic membrane assembly (GO:0097105)3.29131585
73regulation of synaptic plasticity (GO:0048167)3.27098643
74regulation of vesicle fusion (GO:0031338)3.26995943
75regulation of dendritic spine morphogenesis (GO:0061001)3.24753944
76cerebellar granule cell differentiation (GO:0021707)3.23996854
77regulation of synaptic transmission, glutamatergic (GO:0051966)3.21532816
78energy coupled proton transport, down electrochemical gradient (GO:0015985)3.21350688
79ATP synthesis coupled proton transport (GO:0015986)3.21350688
80presynaptic membrane organization (GO:0097090)3.18716259
81membrane depolarization (GO:0051899)3.18093573
82positive regulation of potassium ion transmembrane transport (GO:1901381)3.15983570
83respiratory electron transport chain (GO:0022904)3.15607237
84membrane hyperpolarization (GO:0060081)3.15305535
85long-term synaptic potentiation (GO:0060291)3.14473893
86cell migration in hindbrain (GO:0021535)3.13585983
87response to histamine (GO:0034776)3.11504855
88neuromuscular process controlling balance (GO:0050885)3.10617970
89electron transport chain (GO:0022900)3.10494385
90innervation (GO:0060384)3.09599745
91auditory behavior (GO:0031223)3.09020984
92synapse assembly (GO:0007416)3.08581483
93dendrite morphogenesis (GO:0048813)3.06219501
94behavioral defense response (GO:0002209)3.05859686
95behavioral fear response (GO:0001662)3.05859686
96regulation of neurotransmitter transport (GO:0051588)3.05678538
97positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.00165999
98response to auditory stimulus (GO:0010996)3.00110309
99positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.99851554
100regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.99401508
101establishment of mitochondrion localization (GO:0051654)2.99013590
102glycine transport (GO:0015816)2.97796772
103synaptic transmission (GO:0007268)2.96891505
104vesicle transport along microtubule (GO:0047496)2.96538297
105positive regulation of synapse assembly (GO:0051965)2.95663009
106regulation of voltage-gated calcium channel activity (GO:1901385)2.95625746
107learning (GO:0007612)2.95591806
108negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.94933992
109adult walking behavior (GO:0007628)2.93953123
110neurofilament cytoskeleton organization (GO:0060052)2.93935777
111neuromuscular synaptic transmission (GO:0007274)2.93709390
112fear response (GO:0042596)2.93679809
113neuronal ion channel clustering (GO:0045161)2.92313428
114startle response (GO:0001964)2.92284681
115social behavior (GO:0035176)2.89707742
116intraspecies interaction between organisms (GO:0051703)2.89707742
117behavioral response to cocaine (GO:0048148)2.88880853
118mating behavior (GO:0007617)2.88474036
119positive regulation of neurotransmitter transport (GO:0051590)2.87551642
120regulation of synaptic transmission (GO:0050804)2.86733456
121negative regulation of appetite (GO:0032099)2.83233095
122negative regulation of response to food (GO:0032096)2.83233095
123establishment of protein localization to mitochondrial membrane (GO:0090151)2.82894964
124cochlea development (GO:0090102)2.79371283
125neuronal action potential (GO:0019228)2.79251306
126neurotransmitter uptake (GO:0001504)2.79020397
127potassium ion import (GO:0010107)2.76688652
128potassium ion homeostasis (GO:0055075)2.74279108
129adult behavior (GO:0030534)2.73530392
130serotonin metabolic process (GO:0042428)2.73063967
131negative regulation of heart rate (GO:0010459)2.72282300
132response to amphetamine (GO:0001975)2.67558010
133cerebral cortex radially oriented cell migration (GO:0021799)2.67138447

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* EZH2_22144423_ChIP-Seq_EOC_Human5.87417138
2GBX2_23144817_ChIP-Seq_PC3_Human3.65426222
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.12729097
4JARID2_20064375_ChIP-Seq_MESCs_Mouse3.10018609
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.06909570
6RNF2_18974828_ChIP-Seq_MESCs_Mouse2.72596744
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.72596744
8* REST_21632747_ChIP-Seq_MESCs_Mouse2.69912443
9JARID2_20075857_ChIP-Seq_MESCs_Mouse2.61688136
10SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.57467875
11EZH2_27304074_Chip-Seq_ESCs_Mouse2.56994764
12SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.52216916
13SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.48763356
14MTF2_20144788_ChIP-Seq_MESCs_Mouse2.48312632
15SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.44161110
16* DROSHA_22980978_ChIP-Seq_HELA_Human2.32498331
17EED_16625203_ChIP-ChIP_MESCs_Mouse2.32246667
18RARB_27405468_Chip-Seq_BRAIN_Mouse2.31150102
19HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.30707120
20* EZH2_27294783_Chip-Seq_ESCs_Mouse2.23671223
21SUZ12_27294783_Chip-Seq_ESCs_Mouse2.21119680
22RNF2_27304074_Chip-Seq_ESCs_Mouse2.19294364
23REST_18959480_ChIP-ChIP_MESCs_Mouse2.18763300
24NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.98652581
25IKZF1_21737484_ChIP-ChIP_HCT116_Human1.97689979
26TAF15_26573619_Chip-Seq_HEK293_Human1.94556920
27GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.93005285
28CTBP2_25329375_ChIP-Seq_LNCAP_Human1.89938146
29* CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.89928447
30ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.88602012
31AR_21572438_ChIP-Seq_LNCaP_Human1.87487840
32* SMAD4_21799915_ChIP-Seq_A2780_Human1.75351727
33* CTBP1_25329375_ChIP-Seq_LNCAP_Human1.73360795
34MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.67762283
35* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.67197491
36EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.61853453
37ZFP57_27257070_Chip-Seq_ESCs_Mouse1.58454941
38PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.55821052
39E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.53410206
40ZNF274_21170338_ChIP-Seq_K562_Hela1.51214322
41* RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.49273215
42P300_19829295_ChIP-Seq_ESCs_Human1.48930236
43CBX2_27304074_Chip-Seq_ESCs_Mouse1.44183505
44PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.43826976
45EWS_26573619_Chip-Seq_HEK293_Human1.42001806
46BMI1_23680149_ChIP-Seq_NPCS_Mouse1.41773860
47ERG_21242973_ChIP-ChIP_JURKAT_Human1.41080538
48GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.39846679
49SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.36905150
50* SOX2_21211035_ChIP-Seq_LN229_Gbm1.34951355
51NR3C1_23031785_ChIP-Seq_PC12_Mouse1.34442462
52SMAD3_21741376_ChIP-Seq_EPCs_Human1.34440685
53MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.33123378
54RING1B_27294783_Chip-Seq_ESCs_Mouse1.32961327
55RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.31925117
56IGF1R_20145208_ChIP-Seq_DFB_Human1.29711484
57TOP2B_26459242_ChIP-Seq_MCF-7_Human1.29570043
58* AR_25329375_ChIP-Seq_VCAP_Human1.29536770
59MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.26885083
60* STAT3_23295773_ChIP-Seq_U87_Human1.26056501
61OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.25035642
62RNF2_27304074_Chip-Seq_NSC_Mouse1.24987367
63FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.24391735
64* MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.23309918
65RBPJ_22232070_ChIP-Seq_NCS_Mouse1.23082267
66SMAD_19615063_ChIP-ChIP_OVARY_Human1.22468979
67SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.21891307
68* AR_19668381_ChIP-Seq_PC3_Human1.21659320
69* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.21647925
70POU3F2_20337985_ChIP-ChIP_501MEL_Human1.19893045
71CDX2_19796622_ChIP-Seq_MESCs_Mouse1.18451070
72KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.17794888
73* PIAS1_25552417_ChIP-Seq_VCAP_Human1.15945097
74TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.15894081
75GATA1_26923725_Chip-Seq_HPCs_Mouse1.15241720
76POU5F1_16153702_ChIP-ChIP_HESCs_Human1.13289399
77HTT_18923047_ChIP-ChIP_STHdh_Human1.11527293
78* TCF4_23295773_ChIP-Seq_U87_Human1.11429746
79* ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.10777682
80TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.10761619
81HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.10702347
82RING1B_27294783_Chip-Seq_NPCs_Mouse1.10670726
83P53_22127205_ChIP-Seq_FIBROBLAST_Human1.09504762
84* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.08800095
85NANOG_18555785_Chip-Seq_ESCs_Mouse1.08480965
86ARNT_22903824_ChIP-Seq_MCF-7_Human1.08145716
87FUS_26573619_Chip-Seq_HEK293_Human1.07711143
88MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.06453776
89* YAP1_20516196_ChIP-Seq_MESCs_Mouse1.06337690
90DNAJC2_21179169_ChIP-ChIP_NT2_Human1.05450657
91FLI1_27457419_Chip-Seq_LIVER_Mouse1.04569590
92AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.04425590
93AHR_22903824_ChIP-Seq_MCF-7_Human1.03886142
94UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.03369232
95RUNX2_22187159_ChIP-Seq_PCA_Human1.02160544
96* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.00730815
97* CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00257332
98NR3C1_21868756_ChIP-Seq_MCF10A_Human0.98447702
99LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97875055
100PRDM14_20953172_ChIP-Seq_ESCs_Human0.97373778
101TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97168127
102POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.97168127
103VDR_22108803_ChIP-Seq_LS180_Human0.96559049
104CBP_20019798_ChIP-Seq_JUKART_Human0.96495362
105IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.96495362
106* SMAD3_21741376_ChIP-Seq_ESCs_Human0.94418446
107TP53_22573176_ChIP-Seq_HFKS_Human0.93826245
108* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.93532336
109* SMAD4_21741376_ChIP-Seq_HESCs_Human0.93183701
110PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.93175455
111* P53_22387025_ChIP-Seq_ESCs_Mouse0.92827146
112TAL1_26923725_Chip-Seq_HPCs_Mouse0.92623175
113* SOX9_26525672_Chip-Seq_HEART_Mouse0.92489117
114ER_23166858_ChIP-Seq_MCF-7_Human0.92439913
115GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.92198276
116BCAT_22108803_ChIP-Seq_LS180_Human0.90614496
117* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.89455984
118WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.89169141
119JUN_21703547_ChIP-Seq_K562_Human0.88409561
120* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.88083088
121TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.87635948
122TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.87627235
123ZFP281_18757296_ChIP-ChIP_E14_Mouse0.87264704
124CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.86657123

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.86594586
2MP0003880_abnormal_central_pattern4.84034701
3MP0003635_abnormal_synaptic_transmissio3.97825456
4MP0004270_analgesia3.49404072
5MP0009745_abnormal_behavioral_response3.30561155
6MP0009046_muscle_twitch3.24870413
7MP0002063_abnormal_learning/memory/cond3.12518515
8MP0002064_seizures3.09273144
9MP0001968_abnormal_touch/_nociception3.07471737
10MP0005423_abnormal_somatic_nervous2.99225775
11MP0002572_abnormal_emotion/affect_behav2.70828670
12MP0002272_abnormal_nervous_system2.66377045
13MP0002734_abnormal_mechanical_nocicepti2.65327559
14MP0001486_abnormal_startle_reflex2.48163537
15MP0002735_abnormal_chemical_nociception2.42481241
16MP0002736_abnormal_nociception_after2.35988920
17MP0001501_abnormal_sleep_pattern2.22707853
18MP0002822_catalepsy2.18411499
19MP0001440_abnormal_grooming_behavior2.15774918
20MP0002067_abnormal_sensory_capabilities2.09386797
21MP0002733_abnormal_thermal_nociception2.06548463
22MP0006276_abnormal_autonomic_nervous2.03784805
23MP0001970_abnormal_pain_threshold1.98904001
24MP0002184_abnormal_innervation1.96446860
25MP0008569_lethality_at_weaning1.90296479
26MP0000778_abnormal_nervous_system1.90132145
27MP0005386_behavior/neurological_phenoty1.80459135
28MP0004924_abnormal_behavior1.80459135
29MP0006292_abnormal_olfactory_placode1.78111271
30MP0002557_abnormal_social/conspecific_i1.75343675
31MP0008877_abnormal_DNA_methylation1.69734020
32MP0009379_abnormal_foot_pigmentation1.66003160
33MP0000566_synostosis1.65571189
34MP0004811_abnormal_neuron_physiology1.65359573
35MP0000751_myopathy1.61003615
36MP0003787_abnormal_imprinting1.60975373
37MP0004858_abnormal_nervous_system1.60528598
38MP0001984_abnormal_olfaction1.59049933
39MP0005646_abnormal_pituitary_gland1.58058429
40MP0003329_amyloid_beta_deposits1.55877487
41MP0000955_abnormal_spinal_cord1.54171803
42MP0002909_abnormal_adrenal_gland1.52572174
43MP0004142_abnormal_muscle_tone1.49422722
44MP0003122_maternal_imprinting1.48100109
45MP0009780_abnormal_chondrocyte_physiolo1.47674221
46MP0002882_abnormal_neuron_morphology1.46429846
47MP0004145_abnormal_muscle_electrophysio1.43212446
48MP0003123_paternal_imprinting1.42414507
49MP0001529_abnormal_vocalization1.41059120
50MP0002066_abnormal_motor_capabilities/c1.40933035
51MP0005645_abnormal_hypothalamus_physiol1.39420546
52MP0004215_abnormal_myocardial_fiber1.34829610
53MP0004885_abnormal_endolymph1.33631754
54MP0003879_abnormal_hair_cell1.32820057
55MP0002837_dystrophic_cardiac_calcinosis1.32775651
56MP0001188_hyperpigmentation1.31711702
57MP0001905_abnormal_dopamine_level1.25222458
58MP0005551_abnormal_eye_electrophysiolog1.23701950
59MP0003633_abnormal_nervous_system1.21930054
60MP0001502_abnormal_circadian_rhythm1.20719113
61MP0003136_yellow_coat_color1.13025216
62MP0002152_abnormal_brain_morphology1.11553649
63MP0003646_muscle_fatigue1.07805194
64MP0002102_abnormal_ear_morphology1.07466121
65MP0002229_neurodegeneration1.05633868
66MP0003631_nervous_system_phenotype1.03932688
67MP0004085_abnormal_heartbeat1.03603104
68MP0004133_heterotaxia1.00950705
69MP0003137_abnormal_impulse_conducting0.99609516
70MP0004742_abnormal_vestibular_system0.96397612
71MP0002234_abnormal_pharynx_morphology0.96060217
72MP0002938_white_spotting0.95904416
73MP0004484_altered_response_of0.94855171
74MP0003938_abnormal_ear_development0.93566480
75MP0002653_abnormal_ependyma_morphology0.93372581
76MP0008872_abnormal_physiological_respon0.92378448
77MP0002752_abnormal_somatic_nervous0.91007341
78MP0005394_taste/olfaction_phenotype0.89585718
79MP0005499_abnormal_olfactory_system0.89585718
80MP0001963_abnormal_hearing_physiology0.86309851
81MP0002069_abnormal_eating/drinking_beha0.84772104
82MP0002638_abnormal_pupillary_reflex0.83584648
83MP0008789_abnormal_olfactory_epithelium0.82630371
84MP0006072_abnormal_retinal_apoptosis0.81355773
85MP0004147_increased_porphyrin_level0.80578859
86MP0003634_abnormal_glial_cell0.80571516
87MP0008874_decreased_physiological_sensi0.80136694
88MP0004233_abnormal_muscle_weight0.78796716
89MP0000631_abnormal_neuroendocrine_gland0.78355519
90MP0010386_abnormal_urinary_bladder0.78272710
91MP0000569_abnormal_digit_pigmentation0.77535947
92MP0001485_abnormal_pinna_reflex0.76545766
93MP0003632_abnormal_nervous_system0.72816045
94MP0005535_abnormal_body_temperature0.71577710
95MP0000049_abnormal_middle_ear0.71316953
96MP0001177_atelectasis0.70600366
97MP0003890_abnormal_embryonic-extraembry0.70280776
98MP0003283_abnormal_digestive_organ0.69235660
99MP0005195_abnormal_posterior_eye0.69150343
100MP0005409_darkened_coat_color0.68170505
101MP0003119_abnormal_digestive_system0.67091489
102MP0000920_abnormal_myelination0.66697311
103MP0001293_anophthalmia0.66437840
104MP0004036_abnormal_muscle_relaxation0.65503411
105MP0002751_abnormal_autonomic_nervous0.64788734
106MP0000013_abnormal_adipose_tissue0.63308150
107MP0003121_genomic_imprinting0.62712390
108MP0002090_abnormal_vision0.62703500
109MP0008961_abnormal_basal_metabolism0.62596342
110MP0003861_abnormal_nervous_system0.62463628
111MP0005253_abnormal_eye_physiology0.61818246
112MP0001299_abnormal_eye_distance/0.60671067
113MP0004510_myositis0.60259338
114MP0001986_abnormal_taste_sensitivity0.60201629
115MP0005620_abnormal_muscle_contractility0.60128121
116MP0005084_abnormal_gallbladder_morpholo0.59781935
117MP0003690_abnormal_glial_cell0.59449988
118MP0005187_abnormal_penis_morphology0.58205606
119MP0001943_abnormal_respiration0.58204435
120MP0010769_abnormal_survival0.56089986
121MP0000026_abnormal_inner_ear0.55372816
122MP0002082_postnatal_lethality0.55154635
123MP0010770_preweaning_lethality0.55154635

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.50970761
2Myokymia (HP:0002411)6.20413683
3Focal seizures (HP:0007359)5.64940416
4Visual hallucinations (HP:0002367)5.06011226
5Atonic seizures (HP:0010819)4.72221637
6Epileptic encephalopathy (HP:0200134)4.70614701
7Febrile seizures (HP:0002373)4.64217743
8Progressive cerebellar ataxia (HP:0002073)4.63930565
9Absence seizures (HP:0002121)4.24191606
10Action tremor (HP:0002345)3.92349819
11Dialeptic seizures (HP:0011146)3.85202854
12Generalized tonic-clonic seizures (HP:0002069)3.81133142
13Broad-based gait (HP:0002136)3.70631649
14Acute necrotizing encephalopathy (HP:0006965)3.65254567
15Supranuclear gaze palsy (HP:0000605)3.41356076
16Gaze-evoked nystagmus (HP:0000640)3.33291593
17Progressive macrocephaly (HP:0004481)3.26665000
18Dysdiadochokinesis (HP:0002075)3.25920140
19Abnormal mitochondria in muscle tissue (HP:0008316)3.20751421
20Poor eye contact (HP:0000817)3.19385948
21Hyperventilation (HP:0002883)3.18404941
22Truncal ataxia (HP:0002078)3.10177653
23Ankle clonus (HP:0011448)3.10022298
24Depression (HP:0000716)3.06494663
25Acute encephalopathy (HP:0006846)3.00980394
26Mitochondrial inheritance (HP:0001427)2.98039784
27Impaired vibration sensation in the lower limbs (HP:0002166)2.93735688
28Anxiety (HP:0000739)2.90503384
29Impaired social interactions (HP:0000735)2.90276237
30Abnormal social behavior (HP:0012433)2.90276237
31Mutism (HP:0002300)2.83290968
32Amblyopia (HP:0000646)2.80714136
33Genetic anticipation (HP:0003743)2.80589219
34Urinary bladder sphincter dysfunction (HP:0002839)2.79034745
35Abnormal eating behavior (HP:0100738)2.79000837
36Excessive salivation (HP:0003781)2.77138719
37Drooling (HP:0002307)2.77138719
38Progressive inability to walk (HP:0002505)2.74417232
39Postural instability (HP:0002172)2.70415408
40Ventricular fibrillation (HP:0001663)2.69342464
41Abnormality of the labia minora (HP:0012880)2.69111727
42Pheochromocytoma (HP:0002666)2.66662659
43* Dysmetria (HP:0001310)2.66550253
44Scanning speech (HP:0002168)2.61415257
45Hemiparesis (HP:0001269)2.54995566
46Impaired smooth pursuit (HP:0007772)2.54581061
47Limb dystonia (HP:0002451)2.47380396
48Increased CSF lactate (HP:0002490)2.46152666
49Urinary urgency (HP:0000012)2.44330677
50Papilledema (HP:0001085)2.42166757
51Renal Fanconi syndrome (HP:0001994)2.41483922
52Increased hepatocellular lipid droplets (HP:0006565)2.41324261
53Abnormality of the lower motor neuron (HP:0002366)2.41321741
54Abnormality of the corticospinal tract (HP:0002492)2.41320986
55Absent speech (HP:0001344)2.38524935
56Optic nerve hypoplasia (HP:0000609)2.37734737
57Abnormality of binocular vision (HP:0011514)2.36814841
58Diplopia (HP:0000651)2.36814841
59Spastic gait (HP:0002064)2.36505879
60Medial flaring of the eyebrow (HP:0010747)2.36452413
61Dysmetric saccades (HP:0000641)2.35810719
62Molar tooth sign on MRI (HP:0002419)2.35498216
63Abnormality of midbrain morphology (HP:0002418)2.35498216
64True hermaphroditism (HP:0010459)2.35398492
65Pancreatic fibrosis (HP:0100732)2.35211918
66Termporal pattern (HP:0011008)2.34610270
67Insidious onset (HP:0003587)2.34610270
68Neuroendocrine neoplasm (HP:0100634)2.30475376
69Epileptiform EEG discharges (HP:0011182)2.29767723
70Fetal akinesia sequence (HP:0001989)2.28168131
71Septo-optic dysplasia (HP:0100842)2.27524050
72Abnormality of ocular smooth pursuit (HP:0000617)2.24612858
73Intention tremor (HP:0002080)2.23966488
74Hemiplegia (HP:0002301)2.23902553
75Agitation (HP:0000713)2.23320105
76Bradykinesia (HP:0002067)2.22162734
77Pancreatic cysts (HP:0001737)2.21247387
78Hepatocellular necrosis (HP:0001404)2.20210103
79EEG with generalized epileptiform discharges (HP:0011198)2.19853276
80Nephronophthisis (HP:0000090)2.17395418
81Abnormal EKG (HP:0003115)2.16893327
82Inability to walk (HP:0002540)2.16879474
83Leukodystrophy (HP:0002415)2.16468953
84Polyphagia (HP:0002591)2.15408020
85Prolonged QT interval (HP:0001657)2.15171041
86Stereotypic behavior (HP:0000733)2.14966177
87Cerebral hypomyelination (HP:0006808)2.13325190
88Status epilepticus (HP:0002133)2.11644676
89Torticollis (HP:0000473)2.10417086
90Lipid accumulation in hepatocytes (HP:0006561)2.10168710
91Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.09658773
92Degeneration of the lateral corticospinal tracts (HP:0002314)2.09658773
93Neurofibrillary tangles (HP:0002185)2.08453070
94Hypsarrhythmia (HP:0002521)2.07932427
95Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.07528792
96Sudden death (HP:0001699)2.07528771
97Amyotrophic lateral sclerosis (HP:0007354)2.07522979
98Syncope (HP:0001279)2.05881451
99Sleep apnea (HP:0010535)2.05039290
100Congenital primary aphakia (HP:0007707)2.04566641
101Lower limb muscle weakness (HP:0007340)2.04245977
102Cerebral edema (HP:0002181)2.02939261
103Cerebral inclusion bodies (HP:0100314)2.01977305
104Hepatic necrosis (HP:0002605)2.00773252
105Focal dystonia (HP:0004373)2.00515881
106Gait imbalance (HP:0002141)2.00094556
107Generalized myoclonic seizures (HP:0002123)1.99061456
108Specific learning disability (HP:0001328)1.94849857
109Impaired vibratory sensation (HP:0002495)1.94541033
110Spastic tetraplegia (HP:0002510)1.93588523
111Bundle branch block (HP:0011710)1.93360022
112Genital tract atresia (HP:0001827)1.92564794
113Optic disc pallor (HP:0000543)1.92340015
114Vaginal atresia (HP:0000148)1.91919365
115Morphological abnormality of the pyramidal tract (HP:0002062)1.91579256
116Psychosis (HP:0000709)1.89524133
117Poor suck (HP:0002033)1.89156022
118Gait ataxia (HP:0002066)1.88922685
119Megalencephaly (HP:0001355)1.88098850
120Blue irides (HP:0000635)1.86824161
121Lissencephaly (HP:0001339)1.85590906
122Nephrogenic diabetes insipidus (HP:0009806)1.85450973
123Central scotoma (HP:0000603)1.85201880
124Incomplete penetrance (HP:0003829)1.84927543
125Abnormality of salivation (HP:0100755)1.82992798
126X-linked dominant inheritance (HP:0001423)1.82217575
127Protruding tongue (HP:0010808)1.82131145
128Absent septum pellucidum (HP:0001331)1.80275372
129Hypoventilation (HP:0002791)1.80033064
130Inappropriate behavior (HP:0000719)1.79935878
131Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.78231177
132Abnormality of renal resorption (HP:0011038)1.77561738
133Failure to thrive in infancy (HP:0001531)1.77337421
134Rapidly progressive (HP:0003678)1.74860318
135Abnormality of saccadic eye movements (HP:0000570)1.73361992
136Postural tremor (HP:0002174)1.72308460
137Primary atrial arrhythmia (HP:0001692)1.72287875
138Aplasia/Hypoplasia of the brainstem (HP:0007362)1.72266358
139Hypoplasia of the brainstem (HP:0002365)1.72266358
140Craniofacial dystonia (HP:0012179)1.71697266
141CNS hypomyelination (HP:0003429)1.69196166
142Abnormality of the renal medulla (HP:0100957)1.66779529
143Decreased central vision (HP:0007663)1.65883864
144Muscular hypotonia of the trunk (HP:0008936)1.63169742
1453-Methylglutaconic aciduria (HP:0003535)1.61720023
146Increased intramyocellular lipid droplets (HP:0012240)1.61063738
147Congenital, generalized hypertrichosis (HP:0004540)1.59568457
148Split foot (HP:0001839)1.58382716

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK34.47696051
2MAP3K93.44507652
3MARK13.43952897
4EPHA43.39337600
5MAP3K43.32685997
6MAP2K72.82121875
7MINK12.77894378
8MAP3K122.31017980
9NTRK22.30098511
10CASK2.30033531
11DYRK22.23490719
12MAP2K42.11131473
13PAK62.09057838
14DAPK21.93852428
15PNCK1.82769791
16KSR21.71494238
17NTRK11.68787243
18MAPK131.64535827
19TNIK1.61880349
20RIPK41.61817058
21KSR11.54852749
22CAMKK11.54518385
23PLK21.48497470
24CDK51.48254677
25PRPF4B1.46453873
26PHKG11.45286548
27PHKG21.45286548
28CDK191.44419903
29STK381.44221694
30BMPR1B1.43198007
31PRKD31.42503955
32GRK51.41468211
33SIK21.35517953
34DAPK11.28492535
35UHMK11.27989421
36PRKCG1.23986012
37CAMKK21.17146845
38LATS21.14027006
39CAMK2A1.12894714
40ADRBK21.12436689
41FES1.07897739
42LMTK21.07542827
43ARAF1.02651425
44SGK2231.00482981
45SGK4941.00482981
46CAMK10.96856971
47TRIM280.95392357
48PINK10.94731313
49SGK20.89262892
50TYRO30.87986196
51CAMK2B0.87272229
52MAP3K20.87071713
53PAK30.86787403
54STK110.86631607
55CDK180.86213143
56MAP4K20.84199102
57CDK140.83995968
58CDK150.82770924
59FRK0.82650512
60WNK10.81338882
61MKNK20.79979520
62STK160.79143838
63CSNK1G30.78996320
64CSNK1G10.78423739
65EPHB20.78073481
66GRK10.77820194
67RET0.77338034
68OXSR10.77327140
69ZAK0.76699297
70CSNK1G20.75829796
71DYRK1A0.74141872
72CDC70.73490829
73INSRR0.71851019
74CDK11A0.71759926
75PRKCH0.70579949
76SGK10.67933356
77CAMK2D0.67070379
78TNK20.65867531
79SGK30.64843027
80BMPR20.64717921
81MAP3K130.63424734
82VRK10.62891883
83MARK20.62189795
84NUAK10.61947662
85TAOK10.60876590
86CSNK1E0.60364364
87PLK30.59132768
88CDC42BPA0.58339155
89PRKCE0.58282529
90PTK2B0.57744482
91MAP3K60.57423171
92CAMK2G0.56967650
93CSNK1A1L0.56889151
94FER0.56534158
95GRK70.55741763
96NME10.55381240
97RAF10.54573450
98MUSK0.54346655
99CAMK1G0.54333339
100PRKG10.53495331
101STK390.53043193
102ALK0.52711040
103SIK30.51875828
104CCNB10.51537593
105VRK20.50840738
106CAMK40.49680105
107DYRK30.49671428
108PRKCZ0.49538597
109WNK40.48944092
110RPS6KA30.48834356
111LIMK10.48737450
112PDK10.48312898
113CDK30.46538254
114WNK30.45658070
115CSNK1A10.45566576
116BCR0.44305611
117MAP3K10.43823615
118ROCK20.43774222
119MAPK100.43547680
120PDPK10.42549384
121NEK10.40821855
122AKT30.40624604
123FGFR20.40097120
124ERBB20.38605818
125CSNK1D0.38402801
126FYN0.38373095
127ABL20.37551941
128BRSK10.37155434
129MKNK10.36988254
130PRKCA0.36917656
131PKN10.36782199
132RPS6KA20.36772819
133ERBB30.36231162
134NEK60.36227682
135MAPK120.35886793
136PRKACA0.35059934

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.98029736
2Synaptic vesicle cycle_Homo sapiens_hsa047213.18438534
3GABAergic synapse_Homo sapiens_hsa047272.77469964
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.76125243
5Circadian entrainment_Homo sapiens_hsa047132.69396699
6Long-term potentiation_Homo sapiens_hsa047202.65930561
7Olfactory transduction_Homo sapiens_hsa047402.64595703
8Glutamatergic synapse_Homo sapiens_hsa047242.62233735
9Morphine addiction_Homo sapiens_hsa050322.50031062
10Amphetamine addiction_Homo sapiens_hsa050312.38654899
11Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.19883498
12Dopaminergic synapse_Homo sapiens_hsa047282.17657091
13Salivary secretion_Homo sapiens_hsa049702.11490880
14Taste transduction_Homo sapiens_hsa047421.98173917
15Insulin secretion_Homo sapiens_hsa049111.95019957
16Cholinergic synapse_Homo sapiens_hsa047251.87162033
17Gastric acid secretion_Homo sapiens_hsa049711.86031285
18Long-term depression_Homo sapiens_hsa047301.81697756
19Serotonergic synapse_Homo sapiens_hsa047261.79654353
20Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.75993242
21Aldosterone synthesis and secretion_Homo sapiens_hsa049251.71576500
22Renin secretion_Homo sapiens_hsa049241.69536689
23Ribosome_Homo sapiens_hsa030101.69244529
24Oxytocin signaling pathway_Homo sapiens_hsa049211.62886861
25Calcium signaling pathway_Homo sapiens_hsa040201.62462986
26Cocaine addiction_Homo sapiens_hsa050301.56089532
27Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.53639631
28Cardiac muscle contraction_Homo sapiens_hsa042601.52023367
29Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.51822875
30Protein export_Homo sapiens_hsa030601.50440500
31GnRH signaling pathway_Homo sapiens_hsa049121.44670628
32Phototransduction_Homo sapiens_hsa047441.44069108
33Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.42325439
34Collecting duct acid secretion_Homo sapiens_hsa049661.39959390
35Gap junction_Homo sapiens_hsa045401.33968156
36Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.29463909
37Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.28497848
38cAMP signaling pathway_Homo sapiens_hsa040241.27987538
39Axon guidance_Homo sapiens_hsa043601.17351859
40Type II diabetes mellitus_Homo sapiens_hsa049301.16366525
41Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.13575951
42Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.12347859
43Estrogen signaling pathway_Homo sapiens_hsa049151.10876769
44Phosphatidylinositol signaling system_Homo sapiens_hsa040701.09538525
45cGMP-PKG signaling pathway_Homo sapiens_hsa040221.05297177
46Melanogenesis_Homo sapiens_hsa049161.04733705
47Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.01982570
48Butanoate metabolism_Homo sapiens_hsa006500.99847546
49ErbB signaling pathway_Homo sapiens_hsa040120.99408877
50Dilated cardiomyopathy_Homo sapiens_hsa054140.98007451
51Glioma_Homo sapiens_hsa052140.97908577
52Oocyte meiosis_Homo sapiens_hsa041140.94396453
53RNA polymerase_Homo sapiens_hsa030200.91811087
54Dorso-ventral axis formation_Homo sapiens_hsa043200.91274919
55Vascular smooth muscle contraction_Homo sapiens_hsa042700.90588960
56Pancreatic secretion_Homo sapiens_hsa049720.86462678
57Vibrio cholerae infection_Homo sapiens_hsa051100.85050214
58Proteasome_Homo sapiens_hsa030500.83564273
59Alzheimers disease_Homo sapiens_hsa050100.81947015
60Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.77599750
61Phospholipase D signaling pathway_Homo sapiens_hsa040720.76984307
62Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.73483527
63Oxidative phosphorylation_Homo sapiens_hsa001900.73033506
64Thyroid hormone synthesis_Homo sapiens_hsa049180.71752422
65MAPK signaling pathway_Homo sapiens_hsa040100.71558093
66Choline metabolism in cancer_Homo sapiens_hsa052310.71022893
67Basal transcription factors_Homo sapiens_hsa030220.70868045
68Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.65824955
69Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.65538645
70Parkinsons disease_Homo sapiens_hsa050120.63693576
71Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.63523021
72Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.63137909
73Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.62900134
74Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.62079453
75Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.61641857
76Regulation of autophagy_Homo sapiens_hsa041400.58491315
77Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.58239028
78Glucagon signaling pathway_Homo sapiens_hsa049220.57753503
79Ras signaling pathway_Homo sapiens_hsa040140.57692582
80Neurotrophin signaling pathway_Homo sapiens_hsa047220.57210172
81Hedgehog signaling pathway_Homo sapiens_hsa043400.57192131
82Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.56460660
83VEGF signaling pathway_Homo sapiens_hsa043700.54427855
84Thyroid hormone signaling pathway_Homo sapiens_hsa049190.53768741
85Vitamin B6 metabolism_Homo sapiens_hsa007500.52696184
86Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.52024338
87Steroid biosynthesis_Homo sapiens_hsa001000.51707434
88Folate biosynthesis_Homo sapiens_hsa007900.51592063
89Carbohydrate digestion and absorption_Homo sapiens_hsa049730.50849631
90Wnt signaling pathway_Homo sapiens_hsa043100.50798210
91Circadian rhythm_Homo sapiens_hsa047100.49816536
92Alcoholism_Homo sapiens_hsa050340.49806791
93Rap1 signaling pathway_Homo sapiens_hsa040150.49670071
94Sphingolipid signaling pathway_Homo sapiens_hsa040710.48755508
95Propanoate metabolism_Homo sapiens_hsa006400.47662853
96Linoleic acid metabolism_Homo sapiens_hsa005910.46559243
97Inositol phosphate metabolism_Homo sapiens_hsa005620.46306016
98mTOR signaling pathway_Homo sapiens_hsa041500.45404238
99Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.45387681
100Huntingtons disease_Homo sapiens_hsa050160.44601285
101Insulin signaling pathway_Homo sapiens_hsa049100.43377233
102Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.42976029
103Endometrial cancer_Homo sapiens_hsa052130.42036388
104Purine metabolism_Homo sapiens_hsa002300.40871153
105Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.39677915
106RNA degradation_Homo sapiens_hsa030180.38955278
107Ether lipid metabolism_Homo sapiens_hsa005650.38743401
108Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.38536739
109Renal cell carcinoma_Homo sapiens_hsa052110.38390557
110Longevity regulating pathway - mammal_Homo sapiens_hsa042110.38199293
111Ovarian steroidogenesis_Homo sapiens_hsa049130.38198505
112Basal cell carcinoma_Homo sapiens_hsa052170.37899681
113Fatty acid elongation_Homo sapiens_hsa000620.37679379
114Endocytosis_Homo sapiens_hsa041440.37183129
115Hippo signaling pathway_Homo sapiens_hsa043900.36892671
116Type I diabetes mellitus_Homo sapiens_hsa049400.36674745
117beta-Alanine metabolism_Homo sapiens_hsa004100.35507962
118Arginine and proline metabolism_Homo sapiens_hsa003300.35416368
119Bile secretion_Homo sapiens_hsa049760.33986309
120Peroxisome_Homo sapiens_hsa041460.33134425
121Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.32544297
122alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.32224255
123Nitrogen metabolism_Homo sapiens_hsa009100.31961436
124Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.31469809
125Prion diseases_Homo sapiens_hsa050200.31007810
126SNARE interactions in vesicular transport_Homo sapiens_hsa041300.30975629
127Metabolic pathways_Homo sapiens_hsa011000.29962306
128Homologous recombination_Homo sapiens_hsa034400.29765959
129Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.29141126
130Non-small cell lung cancer_Homo sapiens_hsa052230.28793320
131Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.28654433
132African trypanosomiasis_Homo sapiens_hsa051430.26332472
133Mineral absorption_Homo sapiens_hsa049780.26251712
134Tryptophan metabolism_Homo sapiens_hsa003800.24640529

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