CARHSP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axon ensheathment in central nervous system (GO:0032291)7.73315555
2central nervous system myelination (GO:0022010)7.73315555
3fatty acid elongation (GO:0030497)5.09622417
4regulation of posttranscriptional gene silencing (GO:0060147)4.96208374
5regulation of gene silencing by miRNA (GO:0060964)4.96208374
6regulation of gene silencing by RNA (GO:0060966)4.96208374
7heterochromatin organization (GO:0070828)4.82043861
8L-phenylalanine catabolic process (GO:0006559)4.80747678
9erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)4.80747678
10ribosomal small subunit biogenesis (GO:0042274)4.66656173
11L-phenylalanine metabolic process (GO:0006558)4.59802819
12erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)4.59802819
13myelin maintenance (GO:0043217)4.51933031
14paraxial mesoderm development (GO:0048339)4.48416398
15planar cell polarity pathway involved in neural tube closure (GO:0090179)4.48005737
16cholesterol biosynthetic process (GO:0006695)4.41680919
17alpha-linolenic acid metabolic process (GO:0036109)4.28198724
18ensheathment of neurons (GO:0007272)4.28168456
19axon ensheathment (GO:0008366)4.28168456
20myelination (GO:0042552)4.23710816
21convergent extension (GO:0060026)4.10393207
22viral transcription (GO:0019083)4.04133264
23long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)4.03018272
24regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.91327471
25translational termination (GO:0006415)3.86887219
26fatty-acyl-CoA biosynthetic process (GO:0046949)3.85593534
27sterol biosynthetic process (GO:0016126)3.84171278
28response to methylmercury (GO:0051597)3.81014988
29ribosomal small subunit assembly (GO:0000028)3.63256541
30very long-chain fatty acid metabolic process (GO:0000038)3.60852990
31DNA strand elongation involved in DNA replication (GO:0006271)3.57531584
32pyrimidine nucleobase catabolic process (GO:0006208)3.56066843
33protein-DNA complex disassembly (GO:0032986)3.53484125
34nucleosome disassembly (GO:0006337)3.53484125
35negative regulation of fibrinolysis (GO:0051918)3.49669011
36G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071993.49379986
37DNA strand elongation (GO:0022616)3.47145601
38low-density lipoprotein particle clearance (GO:0034383)3.41386119
39establishment of apical/basal cell polarity (GO:0035089)3.41202972
40sulfur amino acid catabolic process (GO:0000098)3.35164514
41histone arginine methylation (GO:0034969)3.34945765
42long-chain fatty-acyl-CoA metabolic process (GO:0035336)3.34380003
43fatty-acyl-CoA metabolic process (GO:0035337)3.31998522
44translational elongation (GO:0006414)3.31574857
45glyoxylate metabolic process (GO:0046487)3.31045760
46peptidyl-arginine omega-N-methylation (GO:0035247)3.29427749
47DNA unwinding involved in DNA replication (GO:0006268)3.29017277
48positive regulation of oligodendrocyte differentiation (GO:0048714)3.27810273
49heme transport (GO:0015886)3.26782383
50plasma lipoprotein particle clearance (GO:0034381)3.26278450
51thioester biosynthetic process (GO:0035384)3.25973736
52acyl-CoA biosynthetic process (GO:0071616)3.25973736
53nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.22770938
54lung-associated mesenchyme development (GO:0060484)3.21498674
55serine family amino acid catabolic process (GO:0009071)3.19316889
56establishment of monopolar cell polarity (GO:0061162)3.17864942
57establishment or maintenance of monopolar cell polarity (GO:0061339)3.17864942
58protein complex disassembly (GO:0043241)3.13925436
59acetyl-CoA metabolic process (GO:0006084)3.09851507
60cellular protein complex disassembly (GO:0043624)3.08112611
61glycine metabolic process (GO:0006544)3.07954094
62response to lead ion (GO:0010288)3.06696851
63proline biosynthetic process (GO:0006561)3.05801079
64viral life cycle (GO:0019058)3.05379937
65chromosome condensation (GO:0030261)3.04796015
66cysteine metabolic process (GO:0006534)3.04219646
67lens fiber cell development (GO:0070307)3.03884089
68L-serine metabolic process (GO:0006563)3.03329884
69SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.02551883
70peripheral nervous system axon ensheathment (GO:0032292)3.02507087
71myelination in peripheral nervous system (GO:0022011)3.02507087
72regulation of translational fidelity (GO:0006450)3.01073462
73aromatic amino acid family catabolic process (GO:0009074)2.99998362
74protein targeting to ER (GO:0045047)2.99476414
75creatine metabolic process (GO:0006600)2.98004521
76DNA replication initiation (GO:0006270)2.97233344
77telomere maintenance via semi-conservative replication (GO:0032201)2.95697928
78establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.95346073
79cotranslational protein targeting to membrane (GO:0006613)2.95247052
80proline metabolic process (GO:0006560)2.95194806
81ethanol oxidation (GO:0006069)2.93678600
82notochord development (GO:0030903)2.93333277
83regulation of lipoprotein metabolic process (GO:0050746)2.91782856
84establishment of integrated proviral latency (GO:0075713)2.90012958
85regulation of collateral sprouting (GO:0048670)2.87307047
86establishment of mitochondrion localization (GO:0051654)2.86827627
87cholesterol metabolic process (GO:0008203)2.85015524
88homocysteine metabolic process (GO:0050667)2.84370999
89macromolecular complex disassembly (GO:0032984)2.83335749
90amyloid precursor protein metabolic process (GO:0042982)2.83251134
91regulation of fibrinolysis (GO:0051917)2.82939091
92triglyceride biosynthetic process (GO:0019432)2.82254913
93establishment of protein localization to endoplasmic reticulum (GO:0072599)2.80936370
94nucleobase catabolic process (GO:0046113)2.80480703
95isoprenoid biosynthetic process (GO:0008299)2.80194606
96GDP-mannose metabolic process (GO:0019673)2.79075706
97body morphogenesis (GO:0010171)2.78705857
98bile acid biosynthetic process (GO:0006699)2.78203781
99mitotic chromosome condensation (GO:0007076)2.77663838
100DNA strand renaturation (GO:0000733)2.77466212
101NADPH regeneration (GO:0006740)2.77347495
102protein localization to endoplasmic reticulum (GO:0070972)2.76853303
103protein complex localization (GO:0031503)2.76603243
104positive regulation of fatty acid beta-oxidation (GO:0032000)2.76527143
105triglyceride-rich lipoprotein particle remodeling (GO:0034370)2.76088197
106Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.75751846
107response to lipoprotein particle (GO:0055094)2.75142148
108acylglycerol biosynthetic process (GO:0046463)2.74785768
109neutral lipid biosynthetic process (GO:0046460)2.74785768
110coenzyme catabolic process (GO:0009109)2.73592012
111regulation of cholesterol metabolic process (GO:0090181)2.73519848
112astrocyte development (GO:0014002)2.72281708
113DNA replication checkpoint (GO:0000076)2.71522934
114oligodendrocyte differentiation (GO:0048709)2.71492039
115regulation of cholesterol biosynthetic process (GO:0045540)2.71339396
116amyloid precursor protein catabolic process (GO:0042987)2.68750230
117peptidyl-tyrosine autophosphorylation (GO:0038083)2.68687338
118cellular response to follicle-stimulating hormone stimulus (GO:0071372)2.66866378
119sterol metabolic process (GO:0016125)2.63489311
120thioester metabolic process (GO:0035383)2.63412017
121acyl-CoA metabolic process (GO:0006637)2.63412017
122translational initiation (GO:0006413)2.63246856
123peptidyl-arginine methylation (GO:0018216)2.62859614
124peptidyl-arginine N-methylation (GO:0035246)2.62859614
125macroautophagy (GO:0016236)2.61587251
126regulation of cell fate specification (GO:0042659)2.61502394
127outer ear morphogenesis (GO:0042473)2.60876933
128serine family amino acid biosynthetic process (GO:0009070)2.60747136
129negative regulation of androgen receptor signaling pathway (GO:0060766)2.59857246
130regulation of triglyceride catabolic process (GO:0010896)2.59653222
131aspartate family amino acid catabolic process (GO:0009068)2.58292037
132cofactor catabolic process (GO:0051187)2.57424440
133complement activation, alternative pathway (GO:0006957)2.57032673
134negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804)2.56986187
135protein carboxylation (GO:0018214)2.56879526
136peptidyl-glutamic acid carboxylation (GO:0017187)2.56879526
137chromatin assembly (GO:0031497)2.55718278
138protein retention in ER lumen (GO:0006621)2.55180899
139positive regulation of SMAD protein import into nucleus (GO:0060391)2.53323832
140ethanol metabolic process (GO:0006067)2.53060735
141cochlea morphogenesis (GO:0090103)2.52527506
142branching involved in salivary gland morphogenesis (GO:0060445)2.52361860
143maturation of SSU-rRNA (GO:0030490)2.51805826
144regulation of protein activation cascade (GO:2000257)2.51697216
145iron coordination entity transport (GO:1901678)2.51621483
146protein-lipid complex assembly (GO:0065005)2.50483696
147regulation of mammary gland epithelial cell proliferation (GO:0033599)2.48860578
148regulation of establishment of planar polarity (GO:0090175)2.48741331
149lung epithelium development (GO:0060428)2.48461536
150positive regulation of lipoprotein lipase activity (GO:0051006)2.47485817
151positive regulation of triglyceride lipase activity (GO:0061365)2.47485817
152cellular response to cholesterol (GO:0071397)2.46491198
153ATP-dependent chromatin remodeling (GO:0043044)2.46051389
154serine family amino acid metabolic process (GO:0009069)2.45462837
155triglyceride metabolic process (GO:0006641)2.44625990
156non-canonical Wnt signaling pathway (GO:0035567)2.44109857
157bile acid metabolic process (GO:0008206)2.44010316
158aldehyde catabolic process (GO:0046185)2.43481553
159pre-miRNA processing (GO:0031054)2.43441428
160ribonucleoprotein complex biogenesis (GO:0022613)2.42684515
161regulation of stem cell maintenance (GO:2000036)2.42360028
162regulation of complement activation (GO:0030449)2.42175129
163L-alpha-amino acid transmembrane transport (GO:1902475)2.41592139
164rRNA transcription (GO:0009303)2.41366604
165apical protein localization (GO:0045176)2.41224845
166DNA packaging (GO:0006323)2.41089886
167import into cell (GO:0098657)2.41056176
168negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.39967921
169semaphorin-plexin signaling pathway (GO:0071526)2.39620838
170establishment or maintenance of apical/basal cell polarity (GO:0035088)2.39580885
171establishment or maintenance of bipolar cell polarity (GO:0061245)2.39580885
172regulation of autophagic vacuole assembly (GO:2000785)2.39326749
173fibrinolysis (GO:0042730)2.38740283
174hemoglobin metabolic process (GO:0020027)2.38654241
175renal filtration (GO:0097205)2.38488633
176triglyceride homeostasis (GO:0070328)2.36457943
177acylglycerol homeostasis (GO:0055090)2.36457943
178response to mercury ion (GO:0046689)2.35748499
179regulation of mitochondrial translation (GO:0070129)2.35346299
180pentose-phosphate shunt (GO:0006098)2.35046164
181rRNA modification (GO:0000154)2.34667186
182negative regulation of catenin import into nucleus (GO:0035414)2.34426437
183protein localization to kinetochore (GO:0034501)2.34102333
184polarized epithelial cell differentiation (GO:0030859)2.33866233
185protein localization to chromosome, centromeric region (GO:0071459)2.32811589
186regulation of plasminogen activation (GO:0010755)2.31505211
187ribosomal large subunit biogenesis (GO:0042273)2.31129195
188regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.30929947
189cell-cell junction maintenance (GO:0045217)2.30858251
190negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.27572954
191negative regulation of histone methylation (GO:0031061)2.26226331
192chromatin assembly or disassembly (GO:0006333)2.25558231
193cell migration in hindbrain (GO:0021535)2.24578961
194protein targeting to membrane (GO:0006612)2.23834194
1954-hydroxyproline metabolic process (GO:0019471)2.22871910

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse5.26704228
2PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.83619071
3E2F7_22180533_ChIP-Seq_HELA_Human4.52857403
4RXR_22158963_ChIP-Seq_LIVER_Mouse3.76567326
5TP63_17297297_ChIP-ChIP_HaCaT_Human3.63824973
6PPARA_22158963_ChIP-Seq_LIVER_Mouse3.30886414
7TRIM28_21343339_ChIP-Seq_HEK293_Human3.26208015
8LXR_22158963_ChIP-Seq_LIVER_Mouse3.19602662
9* CLOCK_20551151_ChIP-Seq_293T_Human3.14768183
10RARG_19884340_ChIP-ChIP_MEFs_Mouse2.78459238
11HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.72743627
12MYC_18555785_ChIP-Seq_MESCs_Mouse2.72150176
13FOXM1_23109430_ChIP-Seq_U2OS_Human2.68385364
14TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.67077389
15STAT6_21828071_ChIP-Seq_BEAS2B_Human2.55572078
16EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.29157878
17PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.27158787
18FOXO1_23066095_ChIP-Seq_LIVER_Mouse2.26833279
19XRN2_22483619_ChIP-Seq_HELA_Human2.22608361
20ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.21301642
21TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.17208526
22* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.12921040
23EGR1_23403033_ChIP-Seq_LIVER_Mouse2.08147805
24FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.06624495
25MYC_18358816_ChIP-ChIP_MESCs_Mouse2.02573088
26MYC_19079543_ChIP-ChIP_MESCs_Mouse2.00789087
27CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.99068686
28POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.92971690
29NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.84821034
30ESR2_21235772_ChIP-Seq_MCF-7_Human1.84090269
31MYC_19030024_ChIP-ChIP_MESCs_Mouse1.80567973
32P68_20966046_ChIP-Seq_HELA_Human1.79932020
33THAP11_20581084_ChIP-Seq_MESCs_Mouse1.79693721
34* SOX2_27498859_Chip-Seq_STOMACH_Mouse1.75566903
35* TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.75552075
36* SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.70696940
37CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.66469626
38CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.65728052
39SOX2_18555785_ChIP-Seq_MESCs_Mouse1.64830862
40DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.64743488
41TET1_21451524_ChIP-Seq_MESCs_Mouse1.64369463
42EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.62800741
43CTCF_27219007_Chip-Seq_Bcells_Human1.62606504
44* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.61929695
45PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.57011868
46JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.56800745
47NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.55895497
48VDR_21846776_ChIP-Seq_THP-1_Human1.55052745
49MYC_22102868_ChIP-Seq_BL_Human1.52740177
50SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.49661436
51MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.47461703
52FOXO3_23340844_ChIP-Seq_DLD1_Human1.47367915
53OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.45813785
54ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.45761235
55* SALL4_18804426_ChIP-ChIP_XEN_Mouse1.44809822
56RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.44222583
57FOXP1_21924763_ChIP-Seq_HESCs_Human1.44100668
58WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.44047180
59ZFP281_18757296_ChIP-ChIP_E14_Mouse1.41070280
60P300_27058665_Chip-Seq_ZR-75-30cells_Human1.40434277
61SRY_22984422_ChIP-ChIP_TESTIS_Rat1.39308132
62SA1_27219007_Chip-Seq_ERYTHROID_Human1.38498603
63ESR1_20079471_ChIP-ChIP_T-47D_Human1.36752375
64ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.36564517
65SMC4_20622854_ChIP-Seq_HELA_Human1.36514385
66UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.34459310
67MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.33951322
68ELK3_25401928_ChIP-Seq_HUVEC_Human1.32661159
69E2F4_17652178_ChIP-ChIP_JURKAT_Human1.30800090
70MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.30500422
71CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.30385321
72TTF2_22483619_ChIP-Seq_HELA_Human1.30378129
73MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.30014443
74ZNF263_19887448_ChIP-Seq_K562_Human1.29850752
75NANOG_18555785_ChIP-Seq_MESCs_Mouse1.29702489
76POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.28730404
77* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.28192751
78* FOXA2_19822575_ChIP-Seq_HepG2_Human1.26028285
79* RACK7_27058665_Chip-Seq_MCF-7_Human1.25795743
80E2F1_21310950_ChIP-Seq_MCF-7_Human1.24900660
81ESR1_15608294_ChIP-ChIP_MCF-7_Human1.24328658
82ERG_21242973_ChIP-ChIP_JURKAT_Human1.24006429
83PHF8_20622854_ChIP-Seq_HELA_Human1.23869476
84WT1_19549856_ChIP-ChIP_CCG9911_Human1.23655782
85* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.23619153
86TP53_22127205_ChIP-Seq_IMR90_Human1.22880651
87THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.21621391
88ETS1_20019798_ChIP-Seq_JURKAT_Human1.21286413
89PPAR_26484153_Chip-Seq_NCI-H1993_Human1.20920574
90YY1_21170310_ChIP-Seq_MESCs_Mouse1.20281464
91* RARA_24833708_ChIP-Seq_LIVER_Mouse1.19867313
92KLF4_18555785_ChIP-Seq_MESCs_Mouse1.18915847
93* TP53_20018659_ChIP-ChIP_R1E_Mouse1.18802806
94* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.18768521
95* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.17383722
96GABP_19822575_ChIP-Seq_HepG2_Human1.17350072
97* KDM2B_26808549_Chip-Seq_K562_Human1.14716200
98CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.14687677
99TP63_19390658_ChIP-ChIP_HaCaT_Human1.14425633
100CTCF_18555785_ChIP-Seq_MESCs_Mouse1.14243957
101ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.13980905
102EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.13747248
103CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.13737990
104HIF1A_21447827_ChIP-Seq_MCF-7_Human1.13546850
105E2F1_20622854_ChIP-Seq_HELA_Human1.13156492
106GATA3_20176728_ChIP-ChIP_TSCs_Mouse1.12525861
107LXR_22292898_ChIP-Seq_THP-1_Human1.12438958
108SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.10964011
109ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.10920272
110CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.10081827
111NFIB_24661679_ChIP-Seq_LUNG_Mouse1.09944822
112SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.09846100
113CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.09417417
114SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.09299610
115ELF1_20517297_ChIP-Seq_JURKAT_Human1.09101136
116SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.09098029
117NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.09089723
118* OCT4_18692474_ChIP-Seq_MEFs_Mouse1.08938562
119* SOX2_20726797_ChIP-Seq_SW620_Human1.08915477
120SOX2_18692474_ChIP-Seq_MEFs_Mouse1.07932708
121ZFP281_27345836_Chip-Seq_ESCs_Mouse1.07293903
122* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.07198523
123* POU5F1_18692474_ChIP-Seq_MESCs_Mouse1.06887106
124CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.06696800
125ZFX_18555785_ChIP-Seq_MESCs_Mouse1.06693847
126YY1_22570637_ChIP-Seq_MALME-3M_Human1.06620009
127SOX2_16153702_ChIP-ChIP_HESCs_Human1.06570876
128NANOG_21062744_ChIP-ChIP_HESCs_Human1.06461148
129SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.06245578
130SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.05705387
131EP300_21415370_ChIP-Seq_HL-1_Mouse1.03955329
132* KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.03945832
133* SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.03451944
134SA1_27219007_Chip-Seq_Bcells_Human1.03447336
135DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.03340059
136TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.03220875
137BCOR_27268052_Chip-Seq_Bcells_Human1.03049596
138* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.03006121
139TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.02473947
140EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.02266826
141CTCF_21964334_Chip-Seq_Bcells_Human1.02034919
142TCF3_18692474_ChIP-Seq_MEFs_Mouse1.01637828
143P63_26484246_Chip-Seq_KERATINOCYTES_Human1.01599819
144CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.01569593
145GATA4_25053715_ChIP-Seq_YYC3_Human1.01129886
146KAP1_27257070_Chip-Seq_ESCs_Mouse1.01014130
147NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.99181114
148TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.98490252
149SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.98426641
150RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.97100406
151ATF3_27146783_Chip-Seq_COLON_Human0.96245418
152NRF2_20460467_ChIP-Seq_MEFs_Mouse0.96166869
153NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.96166869
154FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.95726671
155KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.95507886
156CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.95307354
157* EOMES_21245162_ChIP-Seq_HESCs_Human0.91143847
158* FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.90877972
159SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.90824525
160CREB1_26743006_Chip-Seq_LNCaP_Human0.90464695
161GATA1_19941826_ChIP-Seq_K562_Human0.90123950
162ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.89892271
163CJUN_26792858_Chip-Seq_BT549_Human0.89606193
164EZH2_18974828_ChIP-Seq_MESCs_Mouse0.89395858
165RNF2_18974828_ChIP-Seq_MESCs_Mouse0.89395858
166TBX20_22080862_ChIP-Seq_HEART_Mouse0.89322107
167TBX20_22328084_ChIP-Seq_HEART_Mouse0.89322107
168KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.87729480
169ISL1_27105846_Chip-Seq_CPCs_Mouse0.87136307
170CTCF_20526341_ChIP-Seq_ESCs_Human0.87069674
171PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.86458890
172* ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.85926030
173* SOX17_20123909_ChIP-Seq_XEN_Mouse0.85388510
174JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.84977660
175NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.84035629
176AR_21909140_ChIP-Seq_LNCAP_Human0.83877715
177NANOG_18692474_ChIP-Seq_MEFs_Mouse0.83540349
178EED_16625203_ChIP-ChIP_MESCs_Mouse0.83348930
179* SMC1_22415368_ChIP-Seq_MEFs_Mouse0.82316908
180ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.81933043

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen3.76800307
2MP0002139_abnormal_hepatobiliary_system3.73637592
3MP0005360_urolithiasis3.02745384
4MP0003806_abnormal_nucleotide_metabolis2.98152685
5MP0006292_abnormal_olfactory_placode2.85264634
6MP0000920_abnormal_myelination2.82227586
7MP0003136_yellow_coat_color2.63826977
8MP0003705_abnormal_hypodermis_morpholog2.51508913
9MP0005377_hearing/vestibular/ear_phenot2.48237783
10MP0003878_abnormal_ear_physiology2.48237783
11MP0003693_abnormal_embryo_hatching2.41344450
12MP0004272_abnormal_basement_membrane2.41079462
13MP0003950_abnormal_plasma_membrane2.34829427
14MP0010030_abnormal_orbit_morphology2.34429211
15MP0005365_abnormal_bile_salt2.30773548
16MP0009840_abnormal_foam_cell2.25289652
17MP0005085_abnormal_gallbladder_physiolo2.21129627
18MP0003122_maternal_imprinting2.19095252
19MP0003111_abnormal_nucleus_morphology2.13791567
20MP0000537_abnormal_urethra_morphology2.13154603
21MP0009379_abnormal_foot_pigmentation2.11201960
22MP0003123_paternal_imprinting2.10244246
23MP0003690_abnormal_glial_cell2.09131872
24MP0002254_reproductive_system_inflammat2.06505493
25MP0005623_abnormal_meninges_morphology2.04716540
26MP0000049_abnormal_middle_ear2.04421294
27MP0004957_abnormal_blastocyst_morpholog2.04287224
28MP0002249_abnormal_larynx_morphology1.95509069
29MP0003329_amyloid_beta_deposits1.92698603
30MP0005083_abnormal_biliary_tract1.90007452
31MP0009053_abnormal_anal_canal1.87329409
32MP0004185_abnormal_adipocyte_glucose1.85690416
33MP0005257_abnormal_intraocular_pressure1.82959482
34MP0001293_anophthalmia1.77943564
35MP0000462_abnormal_digestive_system1.75354179
36MP0008932_abnormal_embryonic_tissue1.74425759
37MP0005451_abnormal_body_composition1.74414016
38MP0003119_abnormal_digestive_system1.68362495
39MP0010329_abnormal_lipoprotein_level1.67578027
40MP0008875_abnormal_xenobiotic_pharmacok1.65025598
41MP0003656_abnormal_erythrocyte_physiolo1.63182293
42MP0005394_taste/olfaction_phenotype1.59295285
43MP0005499_abnormal_olfactory_system1.59295285
44MP0000566_synostosis1.58799394
45MP0001666_abnormal_nutrient_absorption1.56333830
46MP0002089_abnormal_postnatal_growth/wei1.53177172
47MP0003567_abnormal_fetal_cardiomyocyte1.52590820
48MP0002653_abnormal_ependyma_morphology1.52219924
49MP0005666_abnormal_adipose_tissue1.51566632
50MP0003077_abnormal_cell_cycle1.50649230
51MP0008789_abnormal_olfactory_epithelium1.45846432
52MP0003938_abnormal_ear_development1.45609756
53MP0005275_abnormal_skin_tensile1.44777757
54MP0009672_abnormal_birth_weight1.44411933
55MP0000778_abnormal_nervous_system1.42989602
56MP0002938_white_spotting1.42858770
57MP0002118_abnormal_lipid_homeostasis1.39146969
58MP0003195_calcinosis1.39041726
59MP0003890_abnormal_embryonic-extraembry1.38651933
60MP0003634_abnormal_glial_cell1.37128264
61MP0010678_abnormal_skin_adnexa1.36290962
62MP0002295_abnormal_pulmonary_circulatio1.36217044
63MP0003937_abnormal_limbs/digits/tail_de1.35588333
64MP0002697_abnormal_eye_size1.35233643
65MP0000428_abnormal_craniofacial_morphol1.32334752
66MP0005375_adipose_tissue_phenotype1.32019895
67MP0002085_abnormal_embryonic_tissue1.31059477
68MP0001529_abnormal_vocalization1.30195663
69MP0001299_abnormal_eye_distance/1.30031441
70MP0005332_abnormal_amino_acid1.28597213
71MP0003941_abnormal_skin_development1.28531986
72MP0000647_abnormal_sebaceous_gland1.27787954
73MP0000467_abnormal_esophagus_morphology1.27233323
74MP0001188_hyperpigmentation1.25167118
75MP0003252_abnormal_bile_duct1.25151267
76MP0000003_abnormal_adipose_tissue1.25063890
77MP0003011_delayed_dark_adaptation1.23390396
78MP0000733_abnormal_muscle_development1.22731620
79MP0001286_abnormal_eye_development1.22559086
80MP0009384_cardiac_valve_regurgitation1.22440631
81MP0001730_embryonic_growth_arrest1.22039971
82MP0003283_abnormal_digestive_organ1.18872425
83MP0002084_abnormal_developmental_patter1.18198712
84MP0003121_genomic_imprinting1.17451245
85MP0010094_abnormal_chromosome_stability1.16457224
86MP0003115_abnormal_respiratory_system1.15805814
87MP0000604_amyloidosis1.13145180
88MP0003453_abnormal_keratinocyte_physiol1.10590003
89MP0002282_abnormal_trachea_morphology1.08599704
90MP0000678_abnormal_parathyroid_gland1.07594628
91MP0003186_abnormal_redox_activity1.07252280
92MP0000534_abnormal_ureter_morphology1.05958221
93MP0004133_heterotaxia1.05460193
94MP0005410_abnormal_fertilization1.02966261
95MP0003385_abnormal_body_wall1.02452645
96MP0001672_abnormal_embryogenesis/_devel1.01600858
97MP0005380_embryogenesis_phenotype1.01600858
98MP0003942_abnormal_urinary_system1.00768376
99MP0002932_abnormal_joint_morphology0.98457361
100MP0002116_abnormal_craniofacial_bone0.98017185
101MP0005408_hypopigmentation0.97963223
102MP0003632_abnormal_nervous_system0.97844449
103MP0002092_abnormal_eye_morphology0.96284752
104MP0000383_abnormal_hair_follicle0.96190013
105MP0005503_abnormal_tendon_morphology0.95615660
106MP0001346_abnormal_lacrimal_gland0.95225327
107MP0003091_abnormal_cell_migration0.94710496
108MP0000762_abnormal_tongue_morphology0.94486289
109MP0001849_ear_inflammation0.94472172
110MP0001727_abnormal_embryo_implantation0.94266914
111MP0001661_extended_life_span0.93688098
112MP0001958_emphysema0.93060386
113MP0002080_prenatal_lethality0.93003621
114MP0004197_abnormal_fetal_growth/weight/0.92834517
115MP0003566_abnormal_cell_adhesion0.92281052
116MP0001340_abnormal_eyelid_morphology0.89805260
117MP0005076_abnormal_cell_differentiation0.89700280
118MP0003935_abnormal_craniofacial_develop0.89157930
119MP0001697_abnormal_embryo_size0.88245968
120MP0000609_abnormal_liver_physiology0.88167484
121MP0009250_abnormal_appendicular_skeleto0.87826299
122MP0005670_abnormal_white_adipose0.87449427
123MP0005193_abnormal_anterior_eye0.86586179
124MP0003984_embryonic_growth_retardation0.86272311
125MP0003315_abnormal_perineum_morphology0.83830803
126MP0002796_impaired_skin_barrier0.83733896
127MP0002088_abnormal_embryonic_growth/wei0.83349426
128MP0010368_abnormal_lymphatic_system0.81029243
129MP0002111_abnormal_tail_morphology0.81009340
130MP0005508_abnormal_skeleton_morphology0.81006621
131MP0000350_abnormal_cell_proliferation0.80327042
132MP0002210_abnormal_sex_determination0.79727165
133MP0000432_abnormal_head_morphology0.79441932
134MP0005023_abnormal_wound_healing0.78947149
135MP0004134_abnormal_chest_morphology0.78707592
136MP0008260_abnormal_autophagy0.78621192
137MP0005409_darkened_coat_color0.76284031
138MP0004858_abnormal_nervous_system0.74647321
139MP0004885_abnormal_endolymph0.73948002
140MP0003718_maternal_effect0.73382447
141MP0000631_abnormal_neuroendocrine_gland0.72897264
142MP0002234_abnormal_pharynx_morphology0.71633031
143MP0005248_abnormal_Harderian_gland0.71617416
144MP0002081_perinatal_lethality0.71457587
145MP0002233_abnormal_nose_morphology0.71261983
146MP0003698_abnormal_male_reproductive0.71070699
147MP0005391_vision/eye_phenotype0.70890159
148MP0005423_abnormal_somatic_nervous0.70745587
149MP0005584_abnormal_enzyme/coenzyme_acti0.70700522
150MP0002160_abnormal_reproductive_system0.69394223
151MP0003755_abnormal_palate_morphology0.69139283
152MP0003861_abnormal_nervous_system0.69057093
153MP0005501_abnormal_skin_physiology0.68732434
154MP0000579_abnormal_nail_morphology0.66365496
155MP0004130_abnormal_muscle_cell0.65666001
156MP0000747_muscle_weakness0.63632631
157MP0005187_abnormal_penis_morphology0.63149057
158MP0002060_abnormal_skin_morphology0.62535231
159MP0002168_other_aberrant_phenotype0.61595381

Predicted human phenotypes

RankGene SetZ-score
1Neurofibrillary tangles (HP:0002185)4.24042137
2Deep venous thrombosis (HP:0002625)4.23283383
3Degeneration of the lateral corticospinal tracts (HP:0002314)3.77569131
4Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)3.77569131
5Abnormality of aromatic amino acid family metabolism (HP:0004338)3.74177052
6Reticulocytopenia (HP:0001896)3.60141272
7Premature rupture of membranes (HP:0001788)3.53973702
8Xanthomatosis (HP:0000991)3.50692529
9Coronal craniosynostosis (HP:0004440)3.47748711
10Intrahepatic cholestasis (HP:0001406)3.42684229
11Cerebral inclusion bodies (HP:0100314)3.34182614
12Choanal stenosis (HP:0000452)3.33382555
13Partial duplication of thumb phalanx (HP:0009944)3.22358330
14Abnormality of cells of the erythroid lineage (HP:0012130)2.98445041
15Abnormality of the corticospinal tract (HP:0002492)2.97949866
16Rib fusion (HP:0000902)2.95671096
17Partial duplication of the phalanx of hand (HP:0009999)2.87535191
18Hyperlipoproteinemia (HP:0010980)2.81202453
19Abnormal number of erythroid precursors (HP:0012131)2.77279753
20Duplication of thumb phalanx (HP:0009942)2.74219036
21Sensory axonal neuropathy (HP:0003390)2.73910603
22Septo-optic dysplasia (HP:0100842)2.72597257
23Termporal pattern (HP:0011008)2.71013672
24Insidious onset (HP:0003587)2.71013672
25Hepatoblastoma (HP:0002884)2.66279867
26Vaginal fistula (HP:0004320)2.64375397
27Stridor (HP:0010307)2.63434535
28Megalencephaly (HP:0001355)2.61590177
29Abnormality of glycolysis (HP:0004366)2.61301142
30Increased serum pyruvate (HP:0003542)2.61301142
31Turricephaly (HP:0000262)2.60217217
32Abnormality of monocarboxylic acid metabolism (HP:0010996)2.54213309
33Hypoplasia of the capital femoral epiphysis (HP:0003090)2.54186111
34Renal duplication (HP:0000075)2.52107125
35Back pain (HP:0003418)2.50442900
36Cerebral hypomyelination (HP:0006808)2.49438372
37Shallow orbits (HP:0000586)2.48927347
38Onion bulb formation (HP:0003383)2.48556017
39Hyperacusis (HP:0010780)2.42358820
40Absent epiphyses (HP:0010577)2.41160013
41Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.41160013
42Maternal diabetes (HP:0009800)2.38357697
43Prolonged partial thromboplastin time (HP:0003645)2.36839265
44High anterior hairline (HP:0009890)2.35710653
45Small epiphyses (HP:0010585)2.34637497
46Protrusio acetabuli (HP:0003179)2.34246895
47Trigonocephaly (HP:0000243)2.33785635
48Abnormality of the lacrimal duct (HP:0011481)2.32615822
49Axonal loss (HP:0003447)2.31231668
50Renovascular hypertension (HP:0100817)2.30488048
51Aplasia/Hypoplasia of the sacrum (HP:0008517)2.28175527
52Hypobetalipoproteinemia (HP:0003563)2.26912395
53Rectal fistula (HP:0100590)2.24873756
54Rectovaginal fistula (HP:0000143)2.24873756
55Hyporeflexia of lower limbs (HP:0002600)2.23736793
56Complement deficiency (HP:0004431)2.22136856
57Muscle fiber splitting (HP:0003555)2.21156402
58Biconcave vertebral bodies (HP:0004586)2.21027748
59Ileus (HP:0002595)2.20111113
60Abnormal gallbladder physiology (HP:0012438)2.17660461
61Cholecystitis (HP:0001082)2.17660461
62Broad metatarsal (HP:0001783)2.17050659
63Patellar aplasia (HP:0006443)2.15955364
64Cortical dysplasia (HP:0002539)2.14728200
65Absent radius (HP:0003974)2.14551888
66Abnormality of serine family amino acid metabolism (HP:0010894)2.14237473
67Abnormality of glycine metabolism (HP:0010895)2.14237473
68Alacrima (HP:0000522)2.12690187
69Peritonitis (HP:0002586)2.12169384
70Intestinal fistula (HP:0100819)2.10614366
71Abnormal cartilage morphology (HP:0002763)2.09171143
72Aplasia/Hypoplasia of the patella (HP:0006498)2.08323683
73Supranuclear gaze palsy (HP:0000605)2.08169998
74Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.08063061
75Hyperammonemia (HP:0001987)2.07898879
76Abnormal gallbladder morphology (HP:0012437)2.07237243
77Distal upper limb amyotrophy (HP:0007149)2.07064957
78Upper limb amyotrophy (HP:0009129)2.07064957
79Abnormal number of incisors (HP:0011064)2.06748226
80Absent thumb (HP:0009777)2.05949928
81Chromosomal breakage induced by crosslinking agents (HP:0003221)2.05565676
82Bilateral microphthalmos (HP:0007633)2.05470034
83Nasolacrimal duct obstruction (HP:0000579)2.05131797
84Facial hemangioma (HP:0000329)2.03388861
85Atresia of the external auditory canal (HP:0000413)2.03255428
86Anophthalmia (HP:0000528)2.02850589
87Meckel diverticulum (HP:0002245)2.02849393
88Abnormal auditory evoked potentials (HP:0006958)2.01681259
89Epidermoid cyst (HP:0200040)2.01084570
90Breast hypoplasia (HP:0003187)2.00893562
91Hemorrhage of the eye (HP:0011885)1.99018318
92Focal segmental glomerulosclerosis (HP:0000097)1.98933498
93Aplasia involving forearm bones (HP:0009822)1.98860696
94Absent forearm bone (HP:0003953)1.98860696
95Abnormal lung lobation (HP:0002101)1.98401001
96Abnormality of the level of lipoprotein cholesterol (HP:0010979)1.98075722
97Nuclear cataract (HP:0100018)1.97427539
98Birth length less than 3rd percentile (HP:0003561)1.97335386
99Humeroradial synostosis (HP:0003041)1.96253443
100Synostosis involving the elbow (HP:0003938)1.96253443
101Visceral angiomatosis (HP:0100761)1.95174752
102Thin ribs (HP:0000883)1.94867989
103Infantile muscular hypotonia (HP:0008947)1.93587372
104Buphthalmos (HP:0000557)1.93313147
105Cerebral hemorrhage (HP:0001342)1.93081956
106Macrocytic anemia (HP:0001972)1.93038323
107Cholelithiasis (HP:0001081)1.92464930
108Hyperglycinemia (HP:0002154)1.92287579
109Hypolipoproteinemia (HP:0010981)1.92221924
110Spastic paraparesis (HP:0002313)1.91859979
111Broad thumb (HP:0011304)1.91756946
112Abnormality of the ileum (HP:0001549)1.91617899
113Arnold-Chiari malformation (HP:0002308)1.91486283
114Facial cleft (HP:0002006)1.91262151
115Peripheral hypomyelination (HP:0007182)1.89226507
116Spastic gait (HP:0002064)1.89075182
117Increased nuchal translucency (HP:0010880)1.88942182
118Abnormality of dentin (HP:0010299)1.88319646
119Segmental peripheral demyelination/remyelination (HP:0003481)1.88114501
120Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.87372117
121Hypoalphalipoproteinemia (HP:0003233)1.87288060
122Myelomeningocele (HP:0002475)1.86802991
123Glomerulosclerosis (HP:0000096)1.84324655
124Ankle clonus (HP:0011448)1.83457091
125Horseshoe kidney (HP:0000085)1.83202888
126Scapular winging (HP:0003691)1.83143346
127Elfin facies (HP:0004428)1.83095122
128Abnormality of the nasolacrimal system (HP:0000614)1.82894014
129Aplasia/Hypoplasia of the breasts (HP:0010311)1.82532099
130Irregular epiphyses (HP:0010582)1.82098094
131Abnormality of fatty-acid metabolism (HP:0004359)1.81044188
132Diaphragmatic weakness (HP:0009113)1.80538206
133Broad distal phalanx of finger (HP:0009836)1.79859305
134Hammertoe (HP:0001765)1.79764242
135Pterygium (HP:0001059)1.79664578
136Peripheral demyelination (HP:0011096)1.79222154
137Bifid scrotum (HP:0000048)1.79108686
138Preauricular skin tag (HP:0000384)1.79007995
139Esophageal atresia (HP:0002032)1.78652419
140Rectal prolapse (HP:0002035)1.78574541
141Disproportionate tall stature (HP:0001519)1.77451339
142Bronchomalacia (HP:0002780)1.77135517
143Premature skin wrinkling (HP:0100678)1.76851879
144Broad phalanges of the hand (HP:0009768)1.75726621
145Broad toe (HP:0001837)1.74913410
146Breast aplasia (HP:0100783)1.74196024
147Morphological abnormality of the pyramidal tract (HP:0002062)1.74074009
148Leukodystrophy (HP:0002415)1.73947339
149Ectopic kidney (HP:0000086)1.73938477
150Hemangiomatosis (HP:0007461)1.73491210
151Insomnia (HP:0100785)1.73019358
152Difficulty running (HP:0009046)1.72157924
153Abnormality of complement system (HP:0005339)1.71649770
154Hyperextensible skin (HP:0000974)1.71165816
155Polar cataract (HP:0010696)1.71089557
156Abnormality of the aortic arch (HP:0012303)1.70947733
157Ulnar bowing (HP:0003031)1.70730856
158Abnormality of cochlea (HP:0000375)1.70542720
159Abnormality of glutamine family amino acid metabolism (HP:0010902)1.70138374
160Spina bifida occulta (HP:0003298)1.69891509
161Abnormality of the middle phalanges of the toes (HP:0010183)1.69834386
162Broad finger (HP:0001500)1.69419393
163Optic nerve coloboma (HP:0000588)1.69054352
164Absent septum pellucidum (HP:0001331)1.68450086
165Chromsome breakage (HP:0040012)1.67596154
166Abnormality of the gallbladder (HP:0005264)1.67301346
167Abnormality of methionine metabolism (HP:0010901)1.66990396
168Parakeratosis (HP:0001036)1.66667507
169Foot dorsiflexor weakness (HP:0009027)1.65733062
170Hypoplasia of the iris (HP:0007676)1.65545359
171Abnormality of sulfur amino acid metabolism (HP:0004339)1.65407973
172Overriding aorta (HP:0002623)1.65290101
173Poikiloderma (HP:0001029)1.64470406
174Fat malabsorption (HP:0002630)1.63897349
175Aplasia involving bones of the extremities (HP:0009825)1.63667354
176Aplasia involving bones of the upper limbs (HP:0009823)1.63667354
177Aplasia of the phalanges of the hand (HP:0009802)1.63667354
178Capillary hemangiomas (HP:0005306)1.61306705
179Abnormality of reticulocytes (HP:0004312)1.60363977
180Generalized hypotonia (HP:0001290)1.60245534
181Delayed epiphyseal ossification (HP:0002663)1.59704092
182Broad hallux (HP:0010055)1.58461780
183Carpal synostosis (HP:0009702)1.57479428

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK393.85894836
2LIMK13.12300804
3EPHB12.88321138
4VRK22.86092131
5SMG12.85440548
6EEF2K2.84950756
7EPHB22.78575192
8TESK22.76984560
9MET2.74426962
10TRIB32.55147384
11ZAK2.53850452
12BCR2.53320356
13FGFR22.52997004
14CDC72.51639257
15ICK2.29284569
16NEK22.15083489
17TYRO31.98583853
18TESK11.83383645
19PKN11.78400391
20SIK11.75796436
21MAP2K21.74399056
22PBK1.70045862
23OXSR11.69574516
24UHMK11.67290362
25BCKDK1.63873517
26STK161.59387591
27WNK41.56965210
28PDGFRA1.56583442
29DDR21.52687296
30CDK81.51392714
31TTK1.50066319
32NTRK11.49775578
33CDK71.48451083
34NME21.48226837
35ERBB41.46552103
36LATS11.46127374
37CDK191.41563928
38ROCK21.37067534
39PAK31.36667751
40PTK21.35373397
41TAF11.32200539
42RPS6KB21.32186923
43CHEK21.31905136
44CSNK1G31.27659118
45CSNK1A1L1.26152719
46PRKD31.23844691
47ERN11.23104981
48KSR21.21742159
49CDK121.19044635
50MAPKAPK51.18738797
51PASK1.17823074
52SRPK11.17241503
53EPHA21.15829417
54PTK61.15214579
55PAK61.14092209
56ERBB21.12953510
57FGFR41.11795282
58LATS21.09407049
59DYRK1B1.09076391
60BMX1.07292214
61BUB11.05415264
62SIK21.04213881
63ILK1.02799039
64CSNK1G11.01087277
65PAK21.01059211
66LRRK21.00786458
67MAPK151.00582155
68MAP2K10.97375391
69MARK10.96670332
70* DYRK20.96209409
71PLK40.95792359
72CDK140.95141098
73VRK10.94696276
74PLK10.92136002
75PRKD10.89541568
76FGFR10.89278122
77CDK40.88674159
78PAK10.85585736
79ROCK10.85480350
80WNK10.84529049
81MAP3K20.84428859
82BRSK10.84202074
83AURKB0.84106158
84CAMK1D0.83637156
85BRAF0.81859817
86NME10.79960495
87ATR0.79615385
88MELK0.79554412
89RPS6KA20.79048947
90CDK150.78843214
91MST1R0.77922622
92ABL20.77650883
93TTN0.77107017
94DAPK30.74624815
95CSNK1G20.74582663
96FER0.74266351
97CDK180.74101791
98MAP3K80.71556266
99CAMK2B0.71287440
100MTOR0.70984670
101GSK3A0.69885623
102FGR0.68712206
103MAP3K90.67464754
104MOS0.67128080
105PDGFRB0.67067292
106CDK11A0.66675248
107LMTK20.65527129
108CHEK10.65429148
109WEE10.65233751
110STK40.64531799
111IRAK20.61423513
112CAMK1G0.60826970
113KSR10.59684523
114MAP2K70.59184649
115RET0.58404207
116KDR0.57388227
117RPS6KA50.56956069
118CDK20.56217953
119RPS6KC10.55948919
120RPS6KL10.55948919
121CAMK2G0.55496696
122MAP3K100.55339125
123CAMK2D0.51963576
124PAK40.51409685
125NTRK20.50818791
126TLK10.50700900
127AKT20.50676557
128ARAF0.50630340
129MARK20.50427109
130PRKCZ0.50173145
131PKN20.50161181
132* CDK10.50113244
133STK100.49899429
134MAP3K110.49018636
135RPS6KA60.48766922
136DYRK30.48370932
137MAPK110.47769276
138TAOK30.47095433
139PINK10.47039948
140CLK10.46963982
141MST40.44033854
142PDPK10.44007231
143RIPK10.43666379
144AURKA0.41702213
145* RPS6KA10.41630707
146CSNK1E0.38846848
147PTK2B0.36744301
148DMPK0.36624518
149STK30.36100401
150TRPM70.35797696

Predicted pathways (KEGG)

RankGene SetZ-score
1Nitrogen metabolism_Homo sapiens_hsa009103.79278105
2Terpenoid backbone biosynthesis_Homo sapiens_hsa009003.60024851
3Ribosome_Homo sapiens_hsa030103.45470331
4Steroid biosynthesis_Homo sapiens_hsa001003.41179952
5DNA replication_Homo sapiens_hsa030303.35680738
6Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010403.30558132
7Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.03885092
8Fatty acid elongation_Homo sapiens_hsa000623.01837826
9Base excision repair_Homo sapiens_hsa034102.50272281
10Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.48994166
11Primary bile acid biosynthesis_Homo sapiens_hsa001202.36207016
12Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.32830374
13Fatty acid metabolism_Homo sapiens_hsa012122.27761246
14Cyanoamino acid metabolism_Homo sapiens_hsa004602.24024545
15Butanoate metabolism_Homo sapiens_hsa006502.20658900
16Fatty acid degradation_Homo sapiens_hsa000712.12516813
17Sulfur metabolism_Homo sapiens_hsa009202.10897299
18Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.01029714
19Propanoate metabolism_Homo sapiens_hsa006401.92651071
20Mismatch repair_Homo sapiens_hsa034301.90388969
21PPAR signaling pathway_Homo sapiens_hsa033201.87187159
22One carbon pool by folate_Homo sapiens_hsa006701.83997062
23Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.79528957
24Arginine biosynthesis_Homo sapiens_hsa002201.70406061
25Histidine metabolism_Homo sapiens_hsa003401.69697159
26Tryptophan metabolism_Homo sapiens_hsa003801.69303853
27Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.67576848
28Spliceosome_Homo sapiens_hsa030401.64309114
29Vitamin B6 metabolism_Homo sapiens_hsa007501.63966203
30Complement and coagulation cascades_Homo sapiens_hsa046101.58847785
31RNA polymerase_Homo sapiens_hsa030201.57707404
32Fat digestion and absorption_Homo sapiens_hsa049751.49964482
33Cell cycle_Homo sapiens_hsa041101.47743877
34Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.42373884
35Peroxisome_Homo sapiens_hsa041461.38640765
36Chemical carcinogenesis_Homo sapiens_hsa052041.35234996
37Steroid hormone biosynthesis_Homo sapiens_hsa001401.33555161
38Pyruvate metabolism_Homo sapiens_hsa006201.31015758
39Pyrimidine metabolism_Homo sapiens_hsa002401.30138288
40Galactose metabolism_Homo sapiens_hsa000521.28059897
41Glutathione metabolism_Homo sapiens_hsa004801.27425394
42Nucleotide excision repair_Homo sapiens_hsa034201.26117610
43mRNA surveillance pathway_Homo sapiens_hsa030151.23407379
44Ether lipid metabolism_Homo sapiens_hsa005651.21757659
45Arginine and proline metabolism_Homo sapiens_hsa003301.21711181
46Fanconi anemia pathway_Homo sapiens_hsa034601.20476843
47alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.18549306
48Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.17141914
49Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.16112172
50Fatty acid biosynthesis_Homo sapiens_hsa000611.16027720
51Fructose and mannose metabolism_Homo sapiens_hsa000511.15453174
52Homologous recombination_Homo sapiens_hsa034401.15336945
53RNA transport_Homo sapiens_hsa030131.15185526
54Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.10728950
55beta-Alanine metabolism_Homo sapiens_hsa004101.09339438
56Axon guidance_Homo sapiens_hsa043601.09179641
57Linoleic acid metabolism_Homo sapiens_hsa005911.08919115
58Retinol metabolism_Homo sapiens_hsa008301.03745620
59Wnt signaling pathway_Homo sapiens_hsa043101.00894485
60Alcoholism_Homo sapiens_hsa050340.99983702
612-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.99908771
62Central carbon metabolism in cancer_Homo sapiens_hsa052300.99094592
63Tight junction_Homo sapiens_hsa045300.97666196
64Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.97163692
65Folate biosynthesis_Homo sapiens_hsa007900.96573178
66Tyrosine metabolism_Homo sapiens_hsa003500.95766070
67Huntingtons disease_Homo sapiens_hsa050160.92950134
68Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.91107104
69Carbon metabolism_Homo sapiens_hsa012000.90152721
70Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.89934027
71Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.89207788
72Glycerolipid metabolism_Homo sapiens_hsa005610.88782722
73Biosynthesis of amino acids_Homo sapiens_hsa012300.86004684
74Parkinsons disease_Homo sapiens_hsa050120.84942102
75ECM-receptor interaction_Homo sapiens_hsa045120.84556853
76Bile secretion_Homo sapiens_hsa049760.82218369
77Selenocompound metabolism_Homo sapiens_hsa004500.80754647
78Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.79939370
79Hippo signaling pathway_Homo sapiens_hsa043900.79466039
80Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.79439859
81Bladder cancer_Homo sapiens_hsa052190.79414300
82Renal cell carcinoma_Homo sapiens_hsa052110.78685570
83Phenylalanine metabolism_Homo sapiens_hsa003600.76982830
84Hedgehog signaling pathway_Homo sapiens_hsa043400.76901644
85Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.76779311
86Oxidative phosphorylation_Homo sapiens_hsa001900.74530013
87N-Glycan biosynthesis_Homo sapiens_hsa005100.73724623
88Caffeine metabolism_Homo sapiens_hsa002320.72272404
89Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.72052259
90Basal cell carcinoma_Homo sapiens_hsa052170.71728887
91Prion diseases_Homo sapiens_hsa050200.68647453
92Sulfur relay system_Homo sapiens_hsa041220.64843924
93Pentose and glucuronate interconversions_Homo sapiens_hsa000400.64671856
94Cysteine and methionine metabolism_Homo sapiens_hsa002700.63661475
95Thyroid cancer_Homo sapiens_hsa052160.62781572
96Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.62414471
97Purine metabolism_Homo sapiens_hsa002300.60958295
98Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.60329850
99Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.55333409
100Staphylococcus aureus infection_Homo sapiens_hsa051500.53621840
101Endometrial cancer_Homo sapiens_hsa052130.52014909
102Proteasome_Homo sapiens_hsa030500.50890468
103Melanoma_Homo sapiens_hsa052180.49646723
104Drug metabolism - other enzymes_Homo sapiens_hsa009830.49301550
105Focal adhesion_Homo sapiens_hsa045100.47927364
106Glycerophospholipid metabolism_Homo sapiens_hsa005640.47147012
107Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.46915680
108Notch signaling pathway_Homo sapiens_hsa043300.46538446
109Melanogenesis_Homo sapiens_hsa049160.46389323
110Pentose phosphate pathway_Homo sapiens_hsa000300.44795902
111Lysine degradation_Homo sapiens_hsa003100.44762814
112Proteoglycans in cancer_Homo sapiens_hsa052050.43886589
113AMPK signaling pathway_Homo sapiens_hsa041520.43745744
114p53 signaling pathway_Homo sapiens_hsa041150.43595656
115Ovarian steroidogenesis_Homo sapiens_hsa049130.43251681
116Systemic lupus erythematosus_Homo sapiens_hsa053220.42772601
117Small cell lung cancer_Homo sapiens_hsa052220.41503032
118Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.40755682
119Alzheimers disease_Homo sapiens_hsa050100.40657093
120Basal transcription factors_Homo sapiens_hsa030220.39787282
121Vitamin digestion and absorption_Homo sapiens_hsa049770.39023944
122Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.38671700
123Colorectal cancer_Homo sapiens_hsa052100.37696408
124Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.37348380
125Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.37111608
126Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.36618729
127TGF-beta signaling pathway_Homo sapiens_hsa043500.36467582
128Endocytosis_Homo sapiens_hsa041440.36432676
129Prostate cancer_Homo sapiens_hsa052150.36398721
130Adipocytokine signaling pathway_Homo sapiens_hsa049200.35995924
131Cardiac muscle contraction_Homo sapiens_hsa042600.35151491
132Amoebiasis_Homo sapiens_hsa051460.34116224
133Metabolic pathways_Homo sapiens_hsa011000.34104680
134MicroRNAs in cancer_Homo sapiens_hsa052060.33493244
135Maturity onset diabetes of the young_Homo sapiens_hsa049500.33079233
136Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.30742239
137PI3K-Akt signaling pathway_Homo sapiens_hsa041510.28298381
138ABC transporters_Homo sapiens_hsa020100.27739693
139Leukocyte transendothelial migration_Homo sapiens_hsa046700.26978509
140Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.24728439
141Protein digestion and absorption_Homo sapiens_hsa049740.24045823
142Arachidonic acid metabolism_Homo sapiens_hsa005900.24038266
143Adherens junction_Homo sapiens_hsa045200.22850830
144Dorso-ventral axis formation_Homo sapiens_hsa043200.21920390

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