Rank | Gene Set | Z-score |
---|---|---|
1 | folic acid-containing compound biosynthetic process (GO:0009396) | 5.89349271 |
2 | regulation of translational fidelity (GO:0006450) | 5.19419712 |
3 | protein localization to kinetochore (GO:0034501) | 4.88544652 |
4 | COPI coating of Golgi vesicle (GO:0048205) | 4.86868311 |
5 | Golgi transport vesicle coating (GO:0048200) | 4.86868311 |
6 | UDP-N-acetylglucosamine metabolic process (GO:0006047) | 4.58210615 |
7 | serine family amino acid biosynthetic process (GO:0009070) | 4.57324740 |
8 | DNA unwinding involved in DNA replication (GO:0006268) | 4.55586436 |
9 | IMP biosynthetic process (GO:0006188) | 4.51837855 |
10 | formation of translation preinitiation complex (GO:0001731) | 4.51156422 |
11 | nuclear pore organization (GO:0006999) | 4.50566791 |
12 | mitotic sister chromatid segregation (GO:0000070) | 4.41608184 |
13 | regulation of posttranscriptional gene silencing (GO:0060147) | 4.36847434 |
14 | regulation of gene silencing by miRNA (GO:0060964) | 4.36847434 |
15 | regulation of gene silencing by RNA (GO:0060966) | 4.36847434 |
16 | nucleobase biosynthetic process (GO:0046112) | 4.33026891 |
17 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (GO:0070059) | 4.27265399 |
18 | nuclear pore complex assembly (GO:0051292) | 4.24915293 |
19 | mitotic nuclear envelope disassembly (GO:0007077) | 4.22918384 |
20 | tetrahydrofolate metabolic process (GO:0046653) | 4.13215773 |
21 | DNA replication-dependent nucleosome organization (GO:0034723) | 4.11255666 |
22 | DNA replication-dependent nucleosome assembly (GO:0006335) | 4.11255666 |
23 | DNA replication initiation (GO:0006270) | 4.06421310 |
24 | sister chromatid segregation (GO:0000819) | 4.04520410 |
25 | * tRNA aminoacylation for protein translation (GO:0006418) | 3.99009201 |
26 | membrane disassembly (GO:0030397) | 3.96752760 |
27 | nuclear envelope disassembly (GO:0051081) | 3.96752760 |
28 | mitotic metaphase plate congression (GO:0007080) | 3.91694738 |
29 | protein localization to chromosome, centromeric region (GO:0071459) | 3.89685858 |
30 | peptidyl-arginine omega-N-methylation (GO:0035247) | 3.88902945 |
31 | regulation of translational termination (GO:0006449) | 3.80989128 |
32 | * tRNA aminoacylation (GO:0043039) | 3.80913590 |
33 | * amino acid activation (GO:0043038) | 3.80913590 |
34 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.80345024 |
35 | IMP metabolic process (GO:0046040) | 3.79638069 |
36 | purine nucleobase biosynthetic process (GO:0009113) | 3.73984406 |
37 | heterochromatin organization (GO:0070828) | 3.71420928 |
38 | histone arginine methylation (GO:0034969) | 3.69955900 |
39 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.69415811 |
40 | snRNA processing (GO:0016180) | 3.59127692 |
41 | mitochondrial DNA metabolic process (GO:0032042) | 3.58447187 |
42 | DNA geometric change (GO:0032392) | 3.57545768 |
43 | DNA duplex unwinding (GO:0032508) | 3.56872511 |
44 | DNA strand elongation (GO:0022616) | 3.56364341 |
45 | ribosome biogenesis (GO:0042254) | 3.51674114 |
46 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.48189065 |
47 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.48189065 |
48 | L-serine transport (GO:0015825) | 3.47527509 |
49 | maturation of SSU-rRNA (GO:0030490) | 3.45207158 |
50 | DNA replication checkpoint (GO:0000076) | 3.44058331 |
51 | misfolded or incompletely synthesized protein catabolic process (GO:0006515) | 3.44008588 |
52 | endoplasmic reticulum unfolded protein response (GO:0030968) | 3.43493594 |
53 | snRNA metabolic process (GO:0016073) | 3.41816713 |
54 | ribosome assembly (GO:0042255) | 3.39532307 |
55 | regulation of helicase activity (GO:0051095) | 3.36814630 |
56 | regulation of spindle organization (GO:0090224) | 3.36653744 |
57 | peptidyl-arginine N-methylation (GO:0035246) | 3.35782276 |
58 | peptidyl-arginine methylation (GO:0018216) | 3.35782276 |
59 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 3.35240694 |
60 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 3.34451272 |
61 | mitotic chromosome condensation (GO:0007076) | 3.31716564 |
62 | aspartate family amino acid biosynthetic process (GO:0009067) | 3.30822618 |
63 | metaphase plate congression (GO:0051310) | 3.28756583 |
64 | regulation of histone H3-K27 methylation (GO:0061085) | 3.28345335 |
65 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 3.27798611 |
66 | skin morphogenesis (GO:0043589) | 3.26912680 |
67 | cellular response to unfolded protein (GO:0034620) | 3.25567125 |
68 | pteridine-containing compound biosynthetic process (GO:0042559) | 3.24303566 |
69 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.24122972 |
70 | stress granule assembly (GO:0034063) | 3.23573443 |
71 | meiotic chromosome segregation (GO:0045132) | 3.22616610 |
72 | regulation of centrosome cycle (GO:0046605) | 3.22463098 |
73 | cellular response to topologically incorrect protein (GO:0035967) | 3.22000466 |
74 | folic acid-containing compound metabolic process (GO:0006760) | 3.21532213 |
75 | pore complex assembly (GO:0046931) | 3.17475118 |
76 | homocysteine metabolic process (GO:0050667) | 3.17325424 |
77 | regulation of hippo signaling (GO:0035330) | 3.15752610 |
78 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.15633268 |
79 | positive regulation of nuclease activity (GO:0032075) | 3.15466880 |
80 | dosage compensation (GO:0007549) | 3.14697157 |
81 | folic acid metabolic process (GO:0046655) | 3.12967309 |
82 | regulation of mitotic spindle organization (GO:0060236) | 3.11539842 |
83 | serine transport (GO:0032329) | 3.09844972 |
84 | regulation of translational elongation (GO:0006448) | 3.09607388 |
85 | iron ion import (GO:0097286) | 3.09272031 |
86 | ER-nucleus signaling pathway (GO:0006984) | 3.06585525 |
87 | nuclear envelope reassembly (GO:0031468) | 3.06070819 |
88 | mitotic nuclear envelope reassembly (GO:0007084) | 3.06070819 |
89 | establishment of chromosome localization (GO:0051303) | 3.05964240 |
90 | positive regulation of SMAD protein import into nucleus (GO:0060391) | 3.02838187 |
91 | paraxial mesoderm development (GO:0048339) | 3.02614365 |
92 | chaperone-mediated protein complex assembly (GO:0051131) | 3.02338765 |
93 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.01677452 |
94 | nuclear envelope organization (GO:0006998) | 3.00723024 |
95 | spliceosomal snRNP assembly (GO:0000387) | 2.99545555 |
96 | pre-miRNA processing (GO:0031054) | 2.99421181 |
97 | positive regulation of chromosome segregation (GO:0051984) | 2.99382260 |
98 | ribosomal large subunit biogenesis (GO:0042273) | 2.96460565 |
99 | regulation of nuclease activity (GO:0032069) | 2.95519994 |
100 | tRNA methylation (GO:0030488) | 2.95248696 |
101 | proline biosynthetic process (GO:0006561) | 2.92300323 |
102 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 2.92221901 |
103 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 2.92054307 |
104 | regulation of chromosome segregation (GO:0051983) | 2.90392872 |
105 | mitotic recombination (GO:0006312) | 2.89181254 |
106 | telomere maintenance via recombination (GO:0000722) | 2.88092955 |
107 | protein heterotrimerization (GO:0070208) | 2.87749713 |
108 | determination of adult lifespan (GO:0008340) | 2.86968282 |
109 | regulation of centriole replication (GO:0046599) | 2.85425284 |
110 | chromatin assembly (GO:0031497) | 2.84368710 |
111 | telomere maintenance via telomere lengthening (GO:0010833) | 2.84206152 |
112 | protein hydroxylation (GO:0018126) | 2.82536288 |
113 | negative regulation of chromosome segregation (GO:0051985) | 2.81707156 |
114 | positive regulation of histone deacetylation (GO:0031065) | 2.81192739 |
115 | negative regulation of DNA recombination (GO:0045910) | 2.79761796 |
116 | L-serine metabolic process (GO:0006563) | 2.79149264 |
117 | cellular response to glucose starvation (GO:0042149) | 2.79098764 |
118 | establishment of apical/basal cell polarity (GO:0035089) | 2.77530688 |
119 | vesicle coating (GO:0006901) | 2.77186467 |
120 | postreplication repair (GO:0006301) | 2.76919327 |
121 | translational initiation (GO:0006413) | 2.76611901 |
122 | chromatin remodeling at centromere (GO:0031055) | 2.76416194 |
123 | rRNA processing (GO:0006364) | 2.75925803 |
124 | glutamine metabolic process (GO:0006541) | 2.75281871 |
125 | negative regulation of histone methylation (GO:0031061) | 2.73007608 |
126 | DNA conformation change (GO:0071103) | 2.72984922 |
127 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 2.72918860 |
128 | protein localization to chromosome (GO:0034502) | 2.72900045 |
129 | tRNA modification (GO:0006400) | 2.72675900 |
130 | spindle checkpoint (GO:0031577) | 2.72666036 |
131 | attachment of spindle microtubules to kinetochore (GO:0008608) | 2.72624526 |
132 | establishment of integrated proviral latency (GO:0075713) | 2.71750006 |
133 | regulation of sister chromatid cohesion (GO:0007063) | 2.70762223 |
134 | kinetochore organization (GO:0051383) | 2.70758947 |
135 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 2.69973411 |
136 | negative regulation of sister chromatid segregation (GO:0033046) | 2.69973411 |
137 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 2.69973411 |
138 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 2.69973411 |
139 | spindle assembly checkpoint (GO:0071173) | 2.69958703 |
140 | chromosome segregation (GO:0007059) | 2.69926582 |
141 | activation of Rac GTPase activity (GO:0032863) | 2.66335871 |
142 | * tRNA metabolic process (GO:0006399) | 2.66160492 |
143 | response to endoplasmic reticulum stress (GO:0034976) | 2.64092352 |
144 | glomerular epithelial cell development (GO:0072310) | 2.63620643 |
145 | COPII vesicle coating (GO:0048208) | 2.62325160 |
146 | ER overload response (GO:0006983) | 2.60817226 |
147 | dolichol-linked oligosaccharide biosynthetic process (GO:0006488) | 2.60547686 |
148 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 2.59261768 |
149 | sulfur amino acid biosynthetic process (GO:0000097) | 2.57617867 |
150 | telomere maintenance via telomerase (GO:0007004) | 2.57569620 |
151 | GDP-mannose metabolic process (GO:0019673) | 2.54502395 |
152 | rRNA transcription (GO:0009303) | 2.48846804 |
153 | ncRNA 3-end processing (GO:0043628) | 2.48017882 |
154 | nucleotide-sugar biosynthetic process (GO:0009226) | 2.48004198 |
155 | snRNA transcription (GO:0009301) | 2.45550132 |
156 | negative regulation of viral release from host cell (GO:1902187) | 2.44026698 |
157 | cell adhesion mediated by integrin (GO:0033627) | 2.43658707 |
158 | protein K48-linked deubiquitination (GO:0071108) | 2.42607635 |
159 | hemidesmosome assembly (GO:0031581) | 2.42000002 |
160 | mRNA cleavage (GO:0006379) | 2.41803002 |
161 | mitochondrial RNA metabolic process (GO:0000959) | 2.40805734 |
162 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 2.39287252 |
163 | positive regulation of CREB transcription factor activity (GO:0032793) | 2.37163190 |
164 | response to unfolded protein (GO:0006986) | 2.37143509 |
165 | natural killer cell mediated cytotoxicity (GO:0042267) | 2.36997328 |
166 | natural killer cell mediated immunity (GO:0002228) | 2.36997328 |
167 | nucleotide-sugar metabolic process (GO:0009225) | 2.35176178 |
168 | regulation of RNA export from nucleus (GO:0046831) | 2.34494109 |
169 | response to topologically incorrect protein (GO:0035966) | 2.33270193 |
170 | protein export from nucleus (GO:0006611) | 2.32814348 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 7.89910598 |
2 | * MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.23675410 |
3 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 4.22787153 |
4 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.48658327 |
5 | * MYC_19079543_ChIP-ChIP_MESCs_Mouse | 3.23913454 |
6 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.21865595 |
7 | * FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.90091907 |
8 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.81269357 |
9 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.75911175 |
10 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.58868091 |
11 | * NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.44038066 |
12 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.40249626 |
13 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.38901672 |
14 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.32600421 |
15 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.24976069 |
16 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.18935893 |
17 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.18533114 |
18 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.18251063 |
19 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 2.15215935 |
20 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 2.11294984 |
21 | * GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.08448239 |
22 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 2.07026911 |
23 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.02357195 |
24 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 2.01472580 |
25 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.99880342 |
26 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.99365033 |
27 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.99340732 |
28 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.97967650 |
29 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.94627813 |
30 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.89407463 |
31 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.85865526 |
32 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.84987078 |
33 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.84987078 |
34 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.84987078 |
35 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.82904903 |
36 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.82093076 |
37 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.80869744 |
38 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.80643899 |
39 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.79567779 |
40 | * ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.75593208 |
41 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.70431039 |
42 | * ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.69401061 |
43 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.66904389 |
44 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.64472923 |
45 | * GABP_19822575_ChIP-Seq_HepG2_Human | 1.63300027 |
46 | * TTF2_22483619_ChIP-Seq_HELA_Human | 1.61373944 |
47 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.60491633 |
48 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.59629688 |
49 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.58964566 |
50 | MYC_22102868_ChIP-Seq_BL_Human | 1.58922073 |
51 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.57602057 |
52 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.57486831 |
53 | * CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.55470673 |
54 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.54790557 |
55 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.54562824 |
56 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.54077127 |
57 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.54022637 |
58 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.53776872 |
59 | * TP53_22127205_ChIP-Seq_IMR90_Human | 1.53310234 |
60 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.50637971 |
61 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.49688699 |
62 | * PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.49400367 |
63 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.48925090 |
64 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.47826303 |
65 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.47108727 |
66 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.46590661 |
67 | * CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.45881060 |
68 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.45667664 |
69 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.44026423 |
70 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.44007364 |
71 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.42491552 |
72 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.42244246 |
73 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.41718592 |
74 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.40737189 |
75 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.40198762 |
76 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.39463232 |
77 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.38097030 |
78 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.33180284 |
79 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.33180284 |
80 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.32984478 |
81 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.27802113 |
82 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 1.27541275 |
83 | * P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.27479085 |
84 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.27307496 |
85 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.26010705 |
86 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.25723126 |
87 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.24771635 |
88 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.24113504 |
89 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.24035645 |
90 | CHD1_26751641_Chip-Seq_LNCaP_Human | 1.22261001 |
91 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.21858854 |
92 | MAF_26560356_Chip-Seq_TH2_Human | 1.20457200 |
93 | MAF_26560356_Chip-Seq_TH1_Human | 1.20145150 |
94 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.19559558 |
95 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.18990887 |
96 | * KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.18959708 |
97 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.18370040 |
98 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.17662017 |
99 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 1.16946410 |
100 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.16528636 |
101 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.15926460 |
102 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 1.15039188 |
103 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.14605872 |
104 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.14576727 |
105 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 1.13726999 |
106 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.13346223 |
107 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 1.12100704 |
108 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.12027119 |
109 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 1.09555549 |
110 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.08483745 |
111 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 1.08417016 |
112 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 1.07994873 |
113 | * ATF3_27146783_Chip-Seq_COLON_Human | 1.06710524 |
114 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.06705674 |
115 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.06377242 |
116 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.05384211 |
117 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.04366709 |
118 | * UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.04118319 |
119 | * TFAP2A_17053090_ChIP-ChIP_MCF-7_Human | 1.03994577 |
120 | * TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.03944914 |
121 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.02236499 |
122 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.01990745 |
123 | * CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.01416797 |
124 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.01319882 |
125 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.01279368 |
126 | * JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.00897655 |
127 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.00356508 |
128 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.99559984 |
129 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.99075200 |
130 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.97336100 |
131 | * E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.97261430 |
132 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 0.97173425 |
133 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.96915760 |
134 | SOX2_18692474_ChIP-Seq_MESCs_Mouse | 0.95699339 |
135 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 0.94897916 |
136 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.94835954 |
137 | * SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.94507665 |
138 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.93574375 |
139 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.93131355 |
140 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.93004880 |
141 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.92611817 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 4.37629280 |
2 | MP0004957_abnormal_blastocyst_morpholog | 4.20616692 |
3 | MP0003111_abnormal_nucleus_morphology | 4.04003389 |
4 | MP0002254_reproductive_system_inflammat | 3.77257321 |
5 | MP0010094_abnormal_chromosome_stability | 3.70090411 |
6 | MP0010352_gastrointestinal_tract_polyps | 3.50711786 |
7 | MP0003077_abnormal_cell_cycle | 3.48516897 |
8 | MP0008057_abnormal_DNA_replication | 3.08940489 |
9 | MP0004272_abnormal_basement_membrane | 2.89571278 |
10 | MP0001348_abnormal_lacrimal_gland | 2.84156176 |
11 | MP0003705_abnormal_hypodermis_morpholog | 2.79892631 |
12 | MP0003950_abnormal_plasma_membrane | 2.73474603 |
13 | MP0001730_embryonic_growth_arrest | 2.56677646 |
14 | MP0008932_abnormal_embryonic_tissue | 2.53083101 |
15 | MP0000350_abnormal_cell_proliferation | 2.48305205 |
16 | MP0005451_abnormal_body_composition | 2.42804094 |
17 | MP0003806_abnormal_nucleotide_metabolis | 2.41034969 |
18 | MP0003123_paternal_imprinting | 2.40055001 |
19 | MP0008058_abnormal_DNA_repair | 2.38177567 |
20 | MP0005076_abnormal_cell_differentiation | 2.35473065 |
21 | MP0010307_abnormal_tumor_latency | 2.28762214 |
22 | MP0004858_abnormal_nervous_system | 2.22291533 |
23 | MP0004133_heterotaxia | 2.17829942 |
24 | MP0005083_abnormal_biliary_tract | 2.14640165 |
25 | MP0008007_abnormal_cellular_replicative | 2.12288154 |
26 | MP0005380_embryogenesis_phenotype | 2.11962566 |
27 | MP0001672_abnormal_embryogenesis/_devel | 2.11962566 |
28 | MP0003283_abnormal_digestive_organ | 2.10213327 |
29 | MP0004197_abnormal_fetal_growth/weight/ | 2.04117923 |
30 | MP0003890_abnormal_embryonic-extraembry | 2.04077049 |
31 | MP0001873_stomach_inflammation | 1.97550323 |
32 | MP0001697_abnormal_embryo_size | 1.96802111 |
33 | MP0002084_abnormal_developmental_patter | 1.93878074 |
34 | MP0003566_abnormal_cell_adhesion | 1.92228227 |
35 | MP0003984_embryonic_growth_retardation | 1.90549576 |
36 | MP0002088_abnormal_embryonic_growth/wei | 1.88561642 |
37 | MP0002085_abnormal_embryonic_tissue | 1.86197105 |
38 | MP0002080_prenatal_lethality | 1.83252156 |
39 | MP0003119_abnormal_digestive_system | 1.82504769 |
40 | MP0010030_abnormal_orbit_morphology | 1.78871089 |
41 | MP0002060_abnormal_skin_morphology | 1.78231378 |
42 | MP0009840_abnormal_foam_cell | 1.78190195 |
43 | MP0002653_abnormal_ependyma_morphology | 1.73502524 |
44 | MP0008438_abnormal_cutaneous_collagen | 1.70871413 |
45 | MP0002086_abnormal_extraembryonic_tissu | 1.66802691 |
46 | MP0004233_abnormal_muscle_weight | 1.46428619 |
47 | MP0005023_abnormal_wound_healing | 1.45636862 |
48 | MP0003718_maternal_effect | 1.44852494 |
49 | MP0003121_genomic_imprinting | 1.41728076 |
50 | MP0002877_abnormal_melanocyte_morpholog | 1.41605282 |
51 | MP0003941_abnormal_skin_development | 1.38421555 |
52 | MP0002111_abnormal_tail_morphology | 1.36604979 |
53 | MP0005257_abnormal_intraocular_pressure | 1.34603833 |
54 | MP0003959_abnormal_lean_body | 1.31475751 |
55 | MP0003786_premature_aging | 1.23579199 |
56 | MP0000490_abnormal_crypts_of | 1.23445414 |
57 | MP0000313_abnormal_cell_death | 1.22413871 |
58 | MP0008877_abnormal_DNA_methylation | 1.21988779 |
59 | MP0002697_abnormal_eye_size | 1.21986693 |
60 | MP0009053_abnormal_anal_canal | 1.20996334 |
61 | MP0003091_abnormal_cell_migration | 1.20352361 |
62 | MP0002970_abnormal_white_adipose | 1.20233343 |
63 | MP0009384_cardiac_valve_regurgitation | 1.18557944 |
64 | MP0000003_abnormal_adipose_tissue | 1.18021017 |
65 | MP0009333_abnormal_splenocyte_physiolog | 1.17422813 |
66 | MP0000750_abnormal_muscle_regeneration | 1.16116181 |
67 | MP0000537_abnormal_urethra_morphology | 1.15856804 |
68 | MP0004185_abnormal_adipocyte_glucose | 1.15503418 |
69 | MP0003221_abnormal_cardiomyocyte_apopto | 1.15069018 |
70 | MP0000358_abnormal_cell_content/ | 1.11914263 |
71 | MP0001849_ear_inflammation | 1.11681532 |
72 | MP0000733_abnormal_muscle_development | 1.10458919 |
73 | MP0003656_abnormal_erythrocyte_physiolo | 1.10271576 |
74 | MP0001243_abnormal_dermal_layer | 1.07647174 |
75 | MP0005670_abnormal_white_adipose | 1.07558392 |
76 | MP0002019_abnormal_tumor_incidence | 1.05302035 |
77 | MP0005384_cellular_phenotype | 1.02822230 |
78 | MP0004264_abnormal_extraembryonic_tissu | 1.01687285 |
79 | MP0005275_abnormal_skin_tensile | 1.01417229 |
80 | MP0005621_abnormal_cell_physiology | 1.00526606 |
81 | MP0000432_abnormal_head_morphology | 0.95418937 |
82 | MP0000569_abnormal_digit_pigmentation | 0.94738310 |
83 | MP0000858_altered_metastatic_potential | 0.92499703 |
84 | MP0001915_intracranial_hemorrhage | 0.91851507 |
85 | MP0009672_abnormal_birth_weight | 0.90079795 |
86 | MP0009780_abnormal_chondrocyte_physiolo | 0.89548010 |
87 | MP0009703_decreased_birth_body | 0.88264279 |
88 | MP0000428_abnormal_craniofacial_morphol | 0.87994988 |
89 | MP0004947_skin_inflammation | 0.87929482 |
90 | MP0010771_integument_phenotype | 0.87391370 |
91 | MP0001293_anophthalmia | 0.87068639 |
92 | MP0003385_abnormal_body_wall | 0.86552630 |
93 | MP0003937_abnormal_limbs/digits/tail_de | 0.86519332 |
94 | MP0009931_abnormal_skin_appearance | 0.85100439 |
95 | MP0001286_abnormal_eye_development | 0.85093851 |
96 | MP0005266_abnormal_metabolism | 0.84774957 |
97 | MP0001216_abnormal_epidermal_layer | 0.84324493 |
98 | MP0000371_diluted_coat_color | 0.82585715 |
99 | MP0003279_aneurysm | 0.82401774 |
100 | MP0005501_abnormal_skin_physiology | 0.81491150 |
101 | MP0005623_abnormal_meninges_morphology | 0.81463394 |
102 | MP0002269_muscular_atrophy | 0.81164927 |
103 | MP0005220_abnormal_exocrine_pancreas | 0.80651267 |
104 | MP0001661_extended_life_span | 0.79740861 |
105 | MP0003115_abnormal_respiratory_system | 0.77478642 |
106 | MP0003787_abnormal_imprinting | 0.77275598 |
107 | MP0000467_abnormal_esophagus_morphology | 0.76073092 |
108 | MP0003755_abnormal_palate_morphology | 0.75715890 |
109 | MP0008260_abnormal_autophagy | 0.75428984 |
110 | MP0005375_adipose_tissue_phenotype | 0.75306143 |
111 | MP0010234_abnormal_vibrissa_follicle | 0.74551819 |
112 | MP0008770_decreased_survivor_rate | 0.72241085 |
113 | MP0003861_abnormal_nervous_system | 0.72233956 |
114 | MP0001958_emphysema | 0.70497799 |
115 | MP0002160_abnormal_reproductive_system | 0.69822816 |
116 | MP0003763_abnormal_thymus_physiology | 0.68498700 |
117 | MP0002295_abnormal_pulmonary_circulatio | 0.68458413 |
118 | MP0001299_abnormal_eye_distance/ | 0.68042532 |
119 | MP0003567_abnormal_fetal_cardiomyocyte | 0.66891402 |
120 | MP0001145_abnormal_male_reproductive | 0.66508451 |
121 | MP0002092_abnormal_eye_morphology | 0.63755915 |
122 | MP0002210_abnormal_sex_determination | 0.63462041 |
123 | MP0003935_abnormal_craniofacial_develop | 0.62063821 |
124 | MP0001542_abnormal_bone_strength | 0.61728780 |
125 | MP0002396_abnormal_hematopoietic_system | 0.61651500 |
126 | MP0005310_abnormal_salivary_gland | 0.60816674 |
127 | MP0002925_abnormal_cardiovascular_devel | 0.59793760 |
128 | MP0003453_abnormal_keratinocyte_physiol | 0.59243832 |
129 | MP0003448_altered_tumor_morphology | 0.59149321 |
130 | MP0002177_abnormal_outer_ear | 0.58487180 |
131 | MP0000377_abnormal_hair_follicle | 0.58208884 |
132 | MP0005503_abnormal_tendon_morphology | 0.58038333 |
133 | MP0000678_abnormal_parathyroid_gland | 0.58012293 |
134 | MP0000685_abnormal_immune_system | 0.57835415 |
135 | MP0000703_abnormal_thymus_morphology | 0.57573307 |
136 | MP0003172_abnormal_lysosome_physiology | 0.57406581 |
137 | MP0000013_abnormal_adipose_tissue | 0.56805284 |
138 | MP0005389_reproductive_system_phenotype | 0.56205774 |
139 | MP0005395_other_phenotype | 0.55886740 |
140 | MP0003329_amyloid_beta_deposits | 0.54268825 |
141 | MP0002116_abnormal_craniofacial_bone | 0.54164221 |
142 | MP0000477_abnormal_intestine_morphology | 0.54095272 |
143 | MP0000627_abnormal_mammary_gland | 0.53885683 |
144 | MP0003942_abnormal_urinary_system | 0.53695057 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ependymoma (HP:0002888) | 4.44310552 |
2 | Dysmetric saccades (HP:0000641) | 4.19437516 |
3 | Abnormality of the labia minora (HP:0012880) | 3.53841874 |
4 | Astrocytoma (HP:0009592) | 3.51287385 |
5 | Abnormality of the astrocytes (HP:0100707) | 3.51287385 |
6 | Degeneration of anterior horn cells (HP:0002398) | 3.41745655 |
7 | Abnormality of the anterior horn cell (HP:0006802) | 3.41745655 |
8 | Hand muscle atrophy (HP:0009130) | 3.36127892 |
9 | Agnosia (HP:0010524) | 3.25798097 |
10 | Breast hypoplasia (HP:0003187) | 3.22132341 |
11 | Selective tooth agenesis (HP:0001592) | 3.11328063 |
12 | Abnormal gallbladder physiology (HP:0012438) | 3.09774391 |
13 | Cholecystitis (HP:0001082) | 3.09774391 |
14 | Birth length less than 3rd percentile (HP:0003561) | 3.09567016 |
15 | Abnormality of dentin (HP:0010299) | 3.06980080 |
16 | Trismus (HP:0000211) | 2.92031445 |
17 | Medulloblastoma (HP:0002885) | 2.90482625 |
18 | Missing ribs (HP:0000921) | 2.85320684 |
19 | Distal upper limb amyotrophy (HP:0007149) | 2.82698091 |
20 | Upper limb amyotrophy (HP:0009129) | 2.82698091 |
21 | Hyperacusis (HP:0010780) | 2.82158618 |
22 | Abnormality of the calcaneus (HP:0008364) | 2.79456603 |
23 | Insomnia (HP:0100785) | 2.76989063 |
24 | Glioma (HP:0009733) | 2.72626862 |
25 | Carpal bone hypoplasia (HP:0001498) | 2.70009856 |
26 | Protrusio acetabuli (HP:0003179) | 2.68172989 |
27 | Cortical dysplasia (HP:0002539) | 2.67897023 |
28 | Absent radius (HP:0003974) | 2.66600607 |
29 | Follicular hyperkeratosis (HP:0007502) | 2.66501936 |
30 | Atrophic scars (HP:0001075) | 2.64647853 |
31 | Patellar aplasia (HP:0006443) | 2.64249210 |
32 | Rhabdomyosarcoma (HP:0002859) | 2.63631774 |
33 | Colon cancer (HP:0003003) | 2.62785308 |
34 | Deviation of the thumb (HP:0009603) | 2.62125768 |
35 | Nonimmune hydrops fetalis (HP:0001790) | 2.55650784 |
36 | Long palpebral fissure (HP:0000637) | 2.48721690 |
37 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.48601788 |
38 | Aplasia involving forearm bones (HP:0009822) | 2.48028472 |
39 | Absent forearm bone (HP:0003953) | 2.48028472 |
40 | Flat cornea (HP:0007720) | 2.45976099 |
41 | Biliary tract neoplasm (HP:0100574) | 2.45563917 |
42 | Proximal placement of thumb (HP:0009623) | 2.44605321 |
43 | Aplasia/hypoplasia of the humerus (HP:0006507) | 2.42024153 |
44 | Bowel diverticulosis (HP:0005222) | 2.41256217 |
45 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.41015531 |
46 | Upper limb muscle weakness (HP:0003484) | 2.39615185 |
47 | Metaphyseal cupping (HP:0003021) | 2.38466088 |
48 | Bladder diverticulum (HP:0000015) | 2.37903342 |
49 | Rib fusion (HP:0000902) | 2.35145542 |
50 | Spinal muscular atrophy (HP:0007269) | 2.30098265 |
51 | Absent thumb (HP:0009777) | 2.28871273 |
52 | Large hands (HP:0001176) | 2.28623516 |
53 | Poikiloderma (HP:0001029) | 2.28211120 |
54 | Hammertoe (HP:0001765) | 2.26320917 |
55 | Angiofibromas (HP:0010615) | 2.25750968 |
56 | Adenoma sebaceum (HP:0009720) | 2.25750968 |
57 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 2.25573473 |
58 | Elbow flexion contracture (HP:0002987) | 2.23619981 |
59 | Chronic bronchitis (HP:0004469) | 2.22936148 |
60 | Spastic diplegia (HP:0001264) | 2.22500699 |
61 | Soft skin (HP:0000977) | 2.20369765 |
62 | Neoplasm of the pancreas (HP:0002894) | 2.20261434 |
63 | Short humerus (HP:0005792) | 2.20109991 |
64 | Hypoplasia of the pons (HP:0012110) | 2.19886653 |
65 | Breech presentation (HP:0001623) | 2.19202325 |
66 | Oral leukoplakia (HP:0002745) | 2.17973452 |
67 | Spinal rigidity (HP:0003306) | 2.17019534 |
68 | Rough bone trabeculation (HP:0100670) | 2.16937223 |
69 | Cerebral hypomyelination (HP:0006808) | 2.16833796 |
70 | Abnormality of abdominal situs (HP:0011620) | 2.15351716 |
71 | Abdominal situs inversus (HP:0003363) | 2.15351716 |
72 | Cervical subluxation (HP:0003308) | 2.14801507 |
73 | Sparse lateral eyebrow (HP:0005338) | 2.13514151 |
74 | Fragile skin (HP:0001030) | 2.13212656 |
75 | Premature rupture of membranes (HP:0001788) | 2.11035518 |
76 | Pelvic girdle muscle weakness (HP:0003749) | 2.08147688 |
77 | Supernumerary spleens (HP:0009799) | 2.07669994 |
78 | Neoplasm of striated muscle (HP:0009728) | 2.05787546 |
79 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 2.05417640 |
80 | Abnormality of the salivary glands (HP:0010286) | 2.04546068 |
81 | Impulsivity (HP:0100710) | 2.04205069 |
82 | Shoulder girdle muscle weakness (HP:0003547) | 2.03371617 |
83 | Increased density of long bones (HP:0006392) | 2.03052652 |
84 | Biconcave vertebral bodies (HP:0004586) | 2.02969387 |
85 | Natal tooth (HP:0000695) | 2.02568783 |
86 | Genu recurvatum (HP:0002816) | 2.02502942 |
87 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.02295125 |
88 | Abnormality of subcutaneous fat tissue (HP:0001001) | 2.02207929 |
89 | Chromsome breakage (HP:0040012) | 2.01724530 |
90 | Reticulocytopenia (HP:0001896) | 1.99658631 |
91 | Basal cell carcinoma (HP:0002671) | 1.99164625 |
92 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.98436221 |
93 | Wrist flexion contracture (HP:0001239) | 1.97014048 |
94 | Neoplasm of the oral cavity (HP:0100649) | 1.95503776 |
95 | Fused cervical vertebrae (HP:0002949) | 1.95410960 |
96 | Meckel diverticulum (HP:0002245) | 1.94936073 |
97 | Ankle contracture (HP:0006466) | 1.94290072 |
98 | Vertebral clefting (HP:0008428) | 1.93237353 |
99 | Vertebral hypoplasia (HP:0008417) | 1.92285698 |
100 | Aplasia/Hypoplasia of the vertebrae (HP:0008515) | 1.92285698 |
101 | Ulnar bowing (HP:0003031) | 1.91914176 |
102 | Cafe-au-lait spot (HP:0000957) | 1.90095603 |
103 | Disproportionate tall stature (HP:0001519) | 1.90069617 |
104 | Multiple enchondromatosis (HP:0005701) | 1.89974722 |
105 | Abnormality of the pons (HP:0007361) | 1.88940874 |
106 | Long foot (HP:0001833) | 1.88826338 |
107 | Abnormality of the ileum (HP:0001549) | 1.86689884 |
108 | Homocystinuria (HP:0002156) | 1.86501043 |
109 | Abnormality of homocysteine metabolism (HP:0010919) | 1.86501043 |
110 | Protruding ear (HP:0000411) | 1.86301334 |
111 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.85989440 |
112 | 11 pairs of ribs (HP:0000878) | 1.85923709 |
113 | Abnormality of the lower motor neuron (HP:0002366) | 1.85700462 |
114 | Horseshoe kidney (HP:0000085) | 1.82743287 |
115 | Small hand (HP:0200055) | 1.82680360 |
116 | Ankyloglossia (HP:0010296) | 1.82423949 |
117 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.82147328 |
118 | Gastrointestinal carcinoma (HP:0002672) | 1.82147328 |
119 | Abnormal trabecular bone morphology (HP:0100671) | 1.81499144 |
120 | Glossoptosis (HP:0000162) | 1.81387120 |
121 | Congenital hip dislocation (HP:0001374) | 1.81238764 |
122 | Distal sensory impairment (HP:0002936) | 1.80204172 |
123 | Aortic regurgitation (HP:0001659) | 1.79233630 |
124 | Redundant skin (HP:0001582) | 1.79151181 |
125 | Atelectasis (HP:0100750) | 1.78121699 |
126 | Abnormality of chromosome stability (HP:0003220) | 1.77162840 |
127 | Delayed puberty (HP:0000823) | 1.76686619 |
128 | Squamous cell carcinoma (HP:0002860) | 1.76460447 |
129 | Blue sclerae (HP:0000592) | 1.76130364 |
130 | Premature ovarian failure (HP:0008209) | 1.76086883 |
131 | Abnormal number of incisors (HP:0011064) | 1.75852548 |
132 | Abnormality of the preputium (HP:0100587) | 1.74961455 |
133 | Wormian bones (HP:0002645) | 1.74930463 |
134 | Atresia of the external auditory canal (HP:0000413) | 1.72656610 |
135 | Sloping forehead (HP:0000340) | 1.72104019 |
136 | Mild short stature (HP:0003502) | 1.71748119 |
137 | Premature skin wrinkling (HP:0100678) | 1.71567559 |
138 | Increased nuchal translucency (HP:0010880) | 1.71541348 |
139 | Neoplasm of the colon (HP:0100273) | 1.70546981 |
140 | Amaurosis fugax (HP:0100576) | 1.69872838 |
141 | Small intestinal stenosis (HP:0012848) | 1.69491250 |
142 | Duodenal stenosis (HP:0100867) | 1.69491250 |
143 | Genetic anticipation (HP:0003743) | 1.68971197 |
144 | Rhinitis (HP:0012384) | 1.68834460 |
145 | High pitched voice (HP:0001620) | 1.68400009 |
146 | Megalocornea (HP:0000485) | 1.67169245 |
147 | Renal duplication (HP:0000075) | 1.66216536 |
148 | Abnormality of oral frenula (HP:0000190) | 1.65453223 |
149 | Elfin facies (HP:0004428) | 1.64049613 |
150 | Bronchiectasis (HP:0002110) | 1.63015174 |
151 | Pterygium (HP:0001059) | 1.62863234 |
152 | Unilateral renal agenesis (HP:0000122) | 1.62386310 |
153 | Entropion (HP:0000621) | 1.61204450 |
154 | Abnormal ciliary motility (HP:0012262) | 1.61198597 |
155 | Gaze-evoked nystagmus (HP:0000640) | 1.59099898 |
156 | Short nail (HP:0001799) | 1.57725412 |
157 | Long eyelashes (HP:0000527) | 1.57231216 |
158 | Prominent nose (HP:0000448) | 1.56166314 |
159 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.54793267 |
160 | Distal lower limb amyotrophy (HP:0008944) | 1.53481958 |
161 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 1.52977287 |
162 | Overriding aorta (HP:0002623) | 1.52584533 |
163 | Decreased motor nerve conduction velocity (HP:0003431) | 1.51931896 |
164 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.50985622 |
165 | Absent/shortened dynein arms (HP:0200106) | 1.50985622 |
166 | Vertebral compression fractures (HP:0002953) | 1.50367057 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EPHA2 | 3.85611381 |
2 | CDC7 | 3.62086811 |
3 | BUB1 | 3.53924698 |
4 | SMG1 | 3.02246725 |
5 | WEE1 | 2.99888488 |
6 | NEK1 | 2.96568500 |
7 | CDK12 | 2.94971404 |
8 | TSSK6 | 2.74735598 |
9 | EIF2AK1 | 2.53108086 |
10 | TTK | 2.51206387 |
11 | MST1R | 2.47692461 |
12 | PASK | 2.33162291 |
13 | IRAK3 | 2.28246324 |
14 | NEK2 | 2.27864815 |
15 | FRK | 1.99016092 |
16 | SCYL2 | 1.86494530 |
17 | PLK1 | 1.83240121 |
18 | TLK1 | 1.82009534 |
19 | RPS6KB2 | 1.81868665 |
20 | PKN2 | 1.78302163 |
21 | SIK1 | 1.77189586 |
22 | EEF2K | 1.73377211 |
23 | LATS2 | 1.62758865 |
24 | SRPK1 | 1.61429341 |
25 | LMTK2 | 1.60810113 |
26 | PLK3 | 1.58661275 |
27 | AURKA | 1.57303638 |
28 | TRIM28 | 1.56062563 |
29 | CAMK1D | 1.49621287 |
30 | AURKB | 1.45219956 |
31 | SIK2 | 1.44947800 |
32 | MAP3K8 | 1.42990404 |
33 | ATR | 1.41788590 |
34 | EPHB1 | 1.40572778 |
35 | BRSK2 | 1.38809541 |
36 | CDK7 | 1.36230371 |
37 | PAK4 | 1.36086469 |
38 | ALK | 1.34352291 |
39 | RPS6KA4 | 1.33311249 |
40 | CHEK1 | 1.32824210 |
41 | TRPM7 | 1.32195259 |
42 | CHEK2 | 1.29870203 |
43 | TESK2 | 1.27358785 |
44 | EIF2AK3 | 1.26622013 |
45 | AKT3 | 1.25405288 |
46 | TTN | 1.23241691 |
47 | DDR2 | 1.22069359 |
48 | STK10 | 1.16736783 |
49 | CAMK1G | 1.14478571 |
50 | MAP3K10 | 1.13600909 |
51 | MTOR | 1.12614543 |
52 | NTRK1 | 1.11426188 |
53 | BCR | 1.11149291 |
54 | CLK1 | 1.11049091 |
55 | PRKD2 | 1.06984008 |
56 | BRD4 | 1.06194270 |
57 | MAP3K7 | 1.05725471 |
58 | KSR1 | 1.05267338 |
59 | MARK2 | 1.04640788 |
60 | MKNK1 | 1.04289838 |
61 | CDK4 | 1.03436345 |
62 | FLT3 | 1.02276315 |
63 | TESK1 | 1.00429326 |
64 | PRKCI | 0.98786857 |
65 | BMX | 0.98206157 |
66 | CDK2 | 0.93930233 |
67 | KSR2 | 0.93398855 |
68 | MAPKAPK3 | 0.91878048 |
69 | SIK3 | 0.90981178 |
70 | CDK8 | 0.90510225 |
71 | MAP3K13 | 0.89815744 |
72 | STK3 | 0.89715139 |
73 | STK38L | 0.86541332 |
74 | BRSK1 | 0.84341542 |
75 | ERN1 | 0.83728049 |
76 | ADRBK2 | 0.82463678 |
77 | ATM | 0.81977672 |
78 | ICK | 0.81752266 |
79 | PAK1 | 0.80900984 |
80 | PLK4 | 0.80560789 |
81 | NME2 | 0.80144204 |
82 | MAP2K7 | 0.79931770 |
83 | RAF1 | 0.77678906 |
84 | MET | 0.77173214 |
85 | ERBB4 | 0.74909540 |
86 | PRKAA1 | 0.74835890 |
87 | MAPK11 | 0.73935675 |
88 | PAK2 | 0.73767329 |
89 | STK38 | 0.73361708 |
90 | PBK | 0.71220572 |
91 | MAP4K2 | 0.70760069 |
92 | PNCK | 0.69465778 |
93 | HIPK2 | 0.69335009 |
94 | ACVR1B | 0.68038338 |
95 | CSNK2A2 | 0.67368969 |
96 | CDK1 | 0.66838484 |
97 | CDK6 | 0.66485479 |
98 | PDGFRA | 0.65853561 |
99 | PIM1 | 0.65380807 |
100 | CSNK1E | 0.64746247 |
101 | MKNK2 | 0.64386761 |
102 | TGFBR1 | 0.63774387 |
103 | PDK4 | 0.63586938 |
104 | PDK3 | 0.63586938 |
105 | STK4 | 0.63321650 |
106 | AKT2 | 0.62159275 |
107 | BRAF | 0.62099027 |
108 | ZAK | 0.61994638 |
109 | TRIB3 | 0.60022391 |
110 | NME1 | 0.59038846 |
111 | DYRK2 | 0.59017898 |
112 | PRPF4B | 0.58839080 |
113 | LRRK2 | 0.55682976 |
114 | MST4 | 0.52920742 |
115 | DYRK3 | 0.52333578 |
116 | PTK6 | 0.51239668 |
117 | CDK19 | 0.50957145 |
118 | PTK2B | 0.50817449 |
119 | CSNK2A1 | 0.50179781 |
120 | PIM2 | 0.49114647 |
121 | PRKDC | 0.48629710 |
122 | LIMK1 | 0.48536874 |
123 | FGFR1 | 0.47773082 |
124 | VRK1 | 0.47462484 |
125 | ADRBK1 | 0.46440159 |
126 | DAPK1 | 0.45890558 |
127 | MELK | 0.45038632 |
128 | BCKDK | 0.44546635 |
129 | CDK9 | 0.44153349 |
130 | TAOK2 | 0.43807417 |
131 | PDGFRB | 0.43417198 |
132 | PDK2 | 0.42813671 |
133 | PTK2 | 0.42277308 |
134 | LATS1 | 0.41028513 |
135 | MAP3K9 | 0.40553393 |
136 | CHUK | 0.39252487 |
137 | PLK2 | 0.38795818 |
138 | MAP3K14 | 0.38542074 |
139 | RPS6KB1 | 0.37996227 |
140 | DAPK3 | 0.37781901 |
141 | MAP3K11 | 0.37500814 |
142 | CSNK1A1L | 0.37095546 |
143 | AKT1 | 0.35082622 |
144 | MAPK14 | 0.33551707 |
145 | MAP3K6 | 0.33045227 |
146 | GSK3B | 0.27156715 |
Rank | Gene Set | Z-score |
---|---|---|
1 | One carbon pool by folate_Homo sapiens_hsa00670 | 4.52341539 |
2 | * Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 4.37049512 |
3 | Mismatch repair_Homo sapiens_hsa03430 | 4.07828472 |
4 | DNA replication_Homo sapiens_hsa03030 | 4.06771365 |
5 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.60355220 |
6 | RNA transport_Homo sapiens_hsa03013 | 3.34632429 |
7 | Spliceosome_Homo sapiens_hsa03040 | 2.95901119 |
8 | Proteasome_Homo sapiens_hsa03050 | 2.63347101 |
9 | Base excision repair_Homo sapiens_hsa03410 | 2.54745026 |
10 | Cell cycle_Homo sapiens_hsa04110 | 2.42758199 |
11 | RNA polymerase_Homo sapiens_hsa03020 | 2.34004655 |
12 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.33609734 |
13 | Homologous recombination_Homo sapiens_hsa03440 | 2.23192359 |
14 | Ribosome_Homo sapiens_hsa03010 | 2.07593829 |
15 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 2.07527341 |
16 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.87062040 |
17 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.75415385 |
18 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.71962610 |
19 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.69072417 |
20 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.66886186 |
21 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.62937034 |
22 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.54850647 |
23 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.48998885 |
24 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.38429226 |
25 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.38307656 |
26 | RNA degradation_Homo sapiens_hsa03018 | 1.34151600 |
27 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.33331805 |
28 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.30773366 |
29 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.29946419 |
30 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.26828836 |
31 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.25278693 |
32 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.22543179 |
33 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.20198695 |
34 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.18512290 |
35 | Bladder cancer_Homo sapiens_hsa05219 | 1.15474238 |
36 | Carbon metabolism_Homo sapiens_hsa01200 | 1.00761012 |
37 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.99802209 |
38 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.98631268 |
39 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.98511504 |
40 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.96954710 |
41 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.96700143 |
42 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.95574624 |
43 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.90187132 |
44 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.88500189 |
45 | Basal transcription factors_Homo sapiens_hsa03022 | 0.88287784 |
46 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.85101196 |
47 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.80548849 |
48 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.80071125 |
49 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.79357663 |
50 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.78547080 |
51 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.78481318 |
52 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.77658309 |
53 | HTLV-I infection_Homo sapiens_hsa05166 | 0.76832574 |
54 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.74260542 |
55 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.73638623 |
56 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.71773792 |
57 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.71276896 |
58 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.71056746 |
59 | Legionellosis_Homo sapiens_hsa05134 | 0.69698038 |
60 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.67943273 |
61 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.66181522 |
62 | Adherens junction_Homo sapiens_hsa04520 | 0.65995912 |
63 | Purine metabolism_Homo sapiens_hsa00230 | 0.65827153 |
64 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.62652282 |
65 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.62042765 |
66 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.61111906 |
67 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.59267815 |
68 | Insulin resistance_Homo sapiens_hsa04931 | 0.58935376 |
69 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.58167794 |
70 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.58080548 |
71 | Apoptosis_Homo sapiens_hsa04210 | 0.57493846 |
72 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.56333714 |
73 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.56281075 |
74 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.54411424 |
75 | Alcoholism_Homo sapiens_hsa05034 | 0.54202320 |
76 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.53761425 |
77 | Galactose metabolism_Homo sapiens_hsa00052 | 0.53666573 |
78 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.53383098 |
79 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.52988039 |
80 | Measles_Homo sapiens_hsa05162 | 0.52663676 |
81 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.51971907 |
82 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.51626644 |
83 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.51137201 |
84 | Hepatitis C_Homo sapiens_hsa05160 | 0.50731737 |
85 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.50335562 |
86 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.49863845 |
87 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.49820066 |
88 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.49302051 |
89 | Melanoma_Homo sapiens_hsa05218 | 0.49265867 |
90 | Colorectal cancer_Homo sapiens_hsa05210 | 0.48246936 |
91 | Endocytosis_Homo sapiens_hsa04144 | 0.47294853 |
92 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.46453743 |
93 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.46102044 |
94 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.45535922 |
95 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.44346859 |
96 | Prostate cancer_Homo sapiens_hsa05215 | 0.43738512 |
97 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.43480097 |
98 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.41811471 |
99 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.41613124 |
100 | Protein export_Homo sapiens_hsa03060 | 0.40666191 |
101 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.39455077 |
102 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.39139221 |
103 | Tight junction_Homo sapiens_hsa04530 | 0.38475923 |
104 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.38189848 |
105 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.38000378 |
106 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.37036289 |
107 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.36849327 |
108 | Thyroid cancer_Homo sapiens_hsa05216 | 0.36735605 |
109 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.35907209 |
110 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.33237416 |
111 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.32559422 |
112 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.32036439 |
113 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.31434710 |
114 | Hepatitis B_Homo sapiens_hsa05161 | 0.29164032 |
115 | Lysine degradation_Homo sapiens_hsa00310 | 0.28710107 |
116 | Shigellosis_Homo sapiens_hsa05131 | 0.28450483 |
117 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.28033263 |
118 | Endometrial cancer_Homo sapiens_hsa05213 | 0.26950720 |
119 | Focal adhesion_Homo sapiens_hsa04510 | 0.26230826 |
120 | Pathways in cancer_Homo sapiens_hsa05200 | 0.23374483 |
121 | Sulfur relay system_Homo sapiens_hsa04122 | 0.23117337 |
122 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.19784083 |
123 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.18697772 |
124 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.18282023 |
125 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.17745366 |
126 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.16451960 |
127 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.15815422 |
128 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.14998451 |
129 | Phagosome_Homo sapiens_hsa04145 | 0.14804462 |