

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 6.45087815 |
| 2 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 6.36433292 |
| 3 | negative regulation of cell killing (GO:0031342) | 6.36433292 |
| 4 | regulation of regulatory T cell differentiation (GO:0045589) | 5.76036418 |
| 5 | negative T cell selection (GO:0043383) | 5.73872836 |
| 6 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.71776366 |
| 7 | negative regulation of T cell mediated immunity (GO:0002710) | 5.59121943 |
| 8 | tolerance induction (GO:0002507) | 5.30579531 |
| 9 | negative thymic T cell selection (GO:0045060) | 5.27366643 |
| 10 | cellular response to interleukin-15 (GO:0071350) | 5.13697939 |
| 11 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 5.10556000 |
| 12 | response to interleukin-15 (GO:0070672) | 4.90735867 |
| 13 | positive T cell selection (GO:0043368) | 4.71540333 |
| 14 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.71351560 |
| 15 | regulation of T cell tolerance induction (GO:0002664) | 4.68585297 |
| 16 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.68459016 |
| 17 | positive regulation of tolerance induction (GO:0002645) | 4.61238788 |
| 18 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.40007249 |
| 19 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 4.36824962 |
| 20 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.35422396 |
| 21 | regulation of tolerance induction (GO:0002643) | 4.21965422 |
| 22 | T cell selection (GO:0045058) | 4.18435129 |
| 23 | regulation of gamma-delta T cell activation (GO:0046643) | 4.15277012 |
| 24 | positive thymic T cell selection (GO:0045059) | 4.08783379 |
| 25 | mast cell activation (GO:0045576) | 4.06376625 |
| 26 | activated T cell proliferation (GO:0050798) | 4.06192598 |
| 27 | regulation of gamma-delta T cell differentiation (GO:0045586) | 4.06067431 |
| 28 | regulation of alpha-beta T cell proliferation (GO:0046640) | 4.02685306 |
| 29 | leukocyte aggregation (GO:0070486) | 4.02621615 |
| 30 | regulation of T cell mediated cytotoxicity (GO:0001914) | 4.01278630 |
| 31 | positive regulation of granulocyte differentiation (GO:0030854) | 4.00369630 |
| 32 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.88421421 |
| 33 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.83658156 |
| 34 | detection of other organism (GO:0098543) | 3.83605922 |
| 35 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.79197066 |
| 36 | thymic T cell selection (GO:0045061) | 3.78085973 |
| 37 | type I interferon signaling pathway (GO:0060337) | 3.77457599 |
| 38 | cellular response to type I interferon (GO:0071357) | 3.77457599 |
| 39 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.76251808 |
| 40 | response to type I interferon (GO:0034340) | 3.74703789 |
| 41 | positive regulation of T cell differentiation in thymus (GO:0033089) | 3.74215205 |
| 42 | T cell migration (GO:0072678) | 3.73040664 |
| 43 | negative regulation of interleukin-12 production (GO:0032695) | 3.72767894 |
| 44 | response to interferon-beta (GO:0035456) | 3.71849564 |
| 45 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.71233734 |
| 46 | cellular response to interferon-beta (GO:0035458) | 3.61965496 |
| 47 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.58923979 |
| 48 | detection of bacterium (GO:0016045) | 3.58704878 |
| 49 | neutrophil activation involved in immune response (GO:0002283) | 3.56697620 |
| 50 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.53636179 |
| 51 | T cell receptor signaling pathway (GO:0050852) | 3.53012584 |
| 52 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.50931802 |
| 53 | B cell receptor signaling pathway (GO:0050853) | 3.49792708 |
| 54 | immunoglobulin mediated immune response (GO:0016064) | 3.49138197 |
| 55 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.47350827 |
| 56 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 3.44779334 |
| 57 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 3.41987828 |
| 58 | modulation by symbiont of host immune response (GO:0052553) | 3.41987828 |
| 59 | positive regulation by symbiont of host defense response (GO:0052509) | 3.41987828 |
| 60 | modulation by symbiont of host defense response (GO:0052031) | 3.41987828 |
| 61 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 3.41987828 |
| 62 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 3.41987828 |
| 63 | microglial cell activation (GO:0001774) | 3.39913289 |
| 64 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.35008866 |
| 65 | positive regulation of defense response to virus by host (GO:0002230) | 3.31164892 |
| 66 | positive regulation of B cell differentiation (GO:0045579) | 3.28049758 |
| 67 | regulation of B cell differentiation (GO:0045577) | 3.22495033 |
| 68 | regulation of T cell mediated immunity (GO:0002709) | 3.21336376 |
| 69 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.20176395 |
| 70 | detection of external biotic stimulus (GO:0098581) | 3.19935376 |
| 71 | negative regulation of adaptive immune response (GO:0002820) | 3.19749763 |
| 72 | neutrophil activation (GO:0042119) | 3.18931269 |
| 73 | positive regulation of T cell mediated immunity (GO:0002711) | 3.18315436 |
| 74 | alpha-beta T cell differentiation (GO:0046632) | 3.16159460 |
| 75 | positive regulation of interleukin-1 beta secretion (GO:0050718) | 3.15765400 |
| 76 | positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516) | 3.11168820 |
| 77 | negative regulation of B cell proliferation (GO:0030889) | 3.11034743 |
| 78 | negative regulation of B cell mediated immunity (GO:0002713) | 3.09995090 |
| 79 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 3.09995090 |
| 80 | positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372) | 3.09975043 |
| 81 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.09670315 |
| 82 | T cell costimulation (GO:0031295) | 3.09285005 |
| 83 | regulation of interleukin-1 beta secretion (GO:0050706) | 3.09174793 |
| 84 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 3.08221401 |
| 85 | detection of molecule of bacterial origin (GO:0032490) | 3.07751822 |
| 86 | interferon-gamma production (GO:0032609) | 3.07609803 |
| 87 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 3.05530094 |
| 88 | lymphocyte costimulation (GO:0031294) | 3.05070198 |
| 89 | regulation of CD4-positive, alpha-beta T cell activation (GO:2000514) | 3.03366866 |
| 90 | B cell mediated immunity (GO:0019724) | 3.02770146 |
| 91 | positive regulation of interleukin-4 production (GO:0032753) | 2.99135217 |
| 92 | myeloid cell activation involved in immune response (GO:0002275) | 2.98953869 |
| 93 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 2.97868188 |
| 94 | cellular extravasation (GO:0045123) | 2.97857370 |
| 95 | positive regulation of interleukin-1 secretion (GO:0050716) | 2.96548366 |
| 96 | macrophage activation involved in immune response (GO:0002281) | 2.96382098 |
| 97 | mast cell activation involved in immune response (GO:0002279) | 2.95445120 |
| 98 | mast cell degranulation (GO:0043303) | 2.95445120 |
| 99 | positive regulation of interleukin-1 beta production (GO:0032731) | 2.94974383 |
| 100 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.94612129 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 7.09365675 |
| 2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 6.38362715 |
| 3 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 5.58343990 |
| 4 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 4.72042014 |
| 5 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 4.20545215 |
| 6 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.75932467 |
| 7 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.61185260 |
| 8 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.57573135 |
| 9 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.42235885 |
| 10 | MYB_26560356_Chip-Seq_TH2_Human | 3.29545436 |
| 11 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.89206353 |
| 12 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.88696551 |
| 13 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.86106937 |
| 14 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.60752975 |
| 15 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.57982367 |
| 16 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.53829915 |
| 17 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.25873315 |
| 18 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.25640494 |
| 19 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.24772162 |
| 20 | MYB_26560356_Chip-Seq_TH1_Human | 2.23023636 |
| 21 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.20699139 |
| 22 | GATA3_26560356_Chip-Seq_TH2_Human | 2.15414497 |
| 23 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.14133006 |
| 24 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.12495275 |
| 25 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.10840556 |
| 26 | MAF_26560356_Chip-Seq_TH1_Human | 2.10838055 |
| 27 | SPI1_23127762_ChIP-Seq_K562_Human | 1.74965718 |
| 28 | UTX_26944678_Chip-Seq_JUKART_Human | 1.74945979 |
| 29 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.70093327 |
| 30 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.70088379 |
| 31 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.57655888 |
| 32 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.55740755 |
| 33 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.55479220 |
| 34 | MAF_26560356_Chip-Seq_TH2_Human | 1.53638888 |
| 35 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.51725593 |
| 36 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.49382779 |
| 37 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.45881597 |
| 38 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.44399883 |
| 39 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.38087531 |
| 40 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.35931366 |
| 41 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.34510073 |
| 42 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.33206490 |
| 43 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.32407923 |
| 44 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.31850431 |
| 45 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.25557258 |
| 46 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.24641138 |
| 47 | GATA1_22025678_ChIP-Seq_K562_Human | 1.19466587 |
| 48 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.15436332 |
| 49 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.14767533 |
| 50 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.13514212 |
| 51 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.12665946 |
| 52 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.11687999 |
| 53 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.09133145 |
| 54 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.08048050 |
| 55 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.07859538 |
| 56 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.06766031 |
| 57 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.05204771 |
| 58 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.02232005 |
| 59 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.00097990 |
| 60 | SMRT_27268052_Chip-Seq_Bcells_Human | 1.00050132 |
| 61 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.98111084 |
| 62 | GATA3_26560356_Chip-Seq_TH1_Human | 0.98045155 |
| 63 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.97651160 |
| 64 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.96675194 |
| 65 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.96190771 |
| 66 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.94430903 |
| 67 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.91488918 |
| 68 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.91371528 |
| 69 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.90532212 |
| 70 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.89857545 |
| 71 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.88225089 |
| 72 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.86948745 |
| 73 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.85332962 |
| 74 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.84095597 |
| 75 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.83536014 |
| 76 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.83275623 |
| 77 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.80994512 |
| 78 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.79061932 |
| 79 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.78557138 |
| 80 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.74743220 |
| 81 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.74449040 |
| 82 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.73989677 |
| 83 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 0.73340772 |
| 84 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.73298272 |
| 85 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.72077324 |
| 86 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.71851674 |
| 87 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.71797529 |
| 88 | MYC_22102868_ChIP-Seq_BL_Human | 0.70806474 |
| 89 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.70130678 |
| 90 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.69326818 |
| 91 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.69196489 |
| 92 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.68408995 |
| 93 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.66902328 |
| 94 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.66800587 |
| 95 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.66247060 |
| 96 | TP63_23658742_ChIP-Seq_EP156T_Human | 0.66101656 |
| 97 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.65973880 |
| 98 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.65530236 |
| 99 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 0.65215727 |
| 100 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.65160766 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003724_increased_susceptibility_to | 5.00122483 |
| 2 | MP0005671_abnormal_response_to | 3.98839110 |
| 3 | MP0001835_abnormal_antigen_presentation | 3.96207065 |
| 4 | MP0003763_abnormal_thymus_physiology | 3.41308512 |
| 5 | MP0001873_stomach_inflammation | 3.27493498 |
| 6 | MP0001800_abnormal_humoral_immune | 3.22287213 |
| 7 | MP0003436_decreased_susceptibility_to | 3.17169921 |
| 8 | MP0009785_altered_susceptibility_to | 3.16689676 |
| 9 | MP0000685_abnormal_immune_system | 2.97345170 |
| 10 | MP0009333_abnormal_splenocyte_physiolog | 2.93172021 |
| 11 | MP0005000_abnormal_immune_tolerance | 2.92878820 |
| 12 | MP0001790_abnormal_immune_system | 2.90280680 |
| 13 | MP0005387_immune_system_phenotype | 2.90280680 |
| 14 | MP0002723_abnormal_immune_serum | 2.63644889 |
| 15 | MP0004381_abnormal_hair_follicle | 2.61861687 |
| 16 | MP0002166_altered_tumor_susceptibility | 2.54480832 |
| 17 | MP0005025_abnormal_response_to | 2.52853806 |
| 18 | MP0002420_abnormal_adaptive_immunity | 2.49849999 |
| 19 | MP0002452_abnormal_antigen_presenting | 2.48148002 |
| 20 | MP0001819_abnormal_immune_cell | 2.48100998 |
| 21 | MP0002419_abnormal_innate_immunity | 2.47648177 |
| 22 | MP0000465_gastrointestinal_hemorrhage | 2.41551002 |
| 23 | MP0001853_heart_inflammation | 2.39778419 |
| 24 | MP0002148_abnormal_hypersensitivity_rea | 2.35699073 |
| 25 | MP0002405_respiratory_system_inflammati | 2.19157320 |
| 26 | MP0004947_skin_inflammation | 2.18380047 |
| 27 | MP0005075_abnormal_melanosome_morpholog | 2.16240627 |
| 28 | MP0003303_peritoneal_inflammation | 2.11476567 |
| 29 | MP0003866_abnormal_defecation | 2.04730042 |
| 30 | MP0010155_abnormal_intestine_physiology | 2.04292737 |
| 31 | MP0006082_CNS_inflammation | 1.97519610 |
| 32 | MP0002006_tumorigenesis | 1.92717091 |
| 33 | MP0002398_abnormal_bone_marrow | 1.92345169 |
| 34 | MP0000716_abnormal_immune_system | 1.88899030 |
| 35 | MP0001845_abnormal_inflammatory_respons | 1.79458126 |
| 36 | MP0001533_abnormal_skeleton_physiology | 1.69605575 |
| 37 | MP0001851_eye_inflammation | 1.67946137 |
| 38 | MP0002277_abnormal_respiratory_mucosa | 1.67301598 |
| 39 | MP0000703_abnormal_thymus_morphology | 1.61070850 |
| 40 | MP0000858_altered_metastatic_potential | 1.60479890 |
| 41 | MP0000689_abnormal_spleen_morphology | 1.55560216 |
| 42 | MP0003300_gastrointestinal_ulcer | 1.54795408 |
| 43 | MP0009764_decreased_sensitivity_to | 1.54556917 |
| 44 | MP0002722_abnormal_immune_system | 1.51154670 |
| 45 | MP0005310_abnormal_salivary_gland | 1.45873814 |
| 46 | MP0002429_abnormal_blood_cell | 1.42610285 |
| 47 | MP0003172_abnormal_lysosome_physiology | 1.40984158 |
| 48 | MP0005464_abnormal_platelet_physiology | 1.38345636 |
| 49 | MP0002396_abnormal_hematopoietic_system | 1.37495398 |
| 50 | MP0003191_abnormal_cellular_cholesterol | 1.28231839 |
| 51 | MP0008260_abnormal_autophagy | 1.27223145 |
| 52 | MP0008469_abnormal_protein_level | 1.19427209 |
| 53 | MP0003448_altered_tumor_morphology | 1.12248316 |
| 54 | MP0000579_abnormal_nail_morphology | 1.08834766 |
| 55 | MP0009763_increased_sensitivity_to | 1.03514276 |
| 56 | MP0001663_abnormal_digestive_system | 0.97962070 |
| 57 | MP0004883_abnormal_blood_vessel | 0.97767144 |
| 58 | MP0000569_abnormal_digit_pigmentation | 0.96234814 |
| 59 | MP0001986_abnormal_taste_sensitivity | 0.94420483 |
| 60 | MP0003075_altered_response_to | 0.93994684 |
| 61 | MP0002796_impaired_skin_barrier | 0.92657639 |
| 62 | MP0003045_fibrosis | 0.90436652 |
| 63 | MP0005397_hematopoietic_system_phenotyp | 0.88857830 |
| 64 | MP0001545_abnormal_hematopoietic_system | 0.88857830 |
| 65 | MP0004484_altered_response_of | 0.86695779 |
| 66 | MP0002933_joint_inflammation | 0.81869440 |
| 67 | MP0002009_preneoplasia | 0.81799295 |
| 68 | MP0002998_abnormal_bone_remodeling | 0.81363750 |
| 69 | MP0005166_decreased_susceptibility_to | 0.76215358 |
| 70 | MP0002132_abnormal_respiratory_system | 0.73717201 |
| 71 | MP0002098_abnormal_vibrissa_morphology | 0.71229282 |
| 72 | MP0005164_abnormal_response_to | 0.71130286 |
| 73 | MP0001919_abnormal_reproductive_system | 0.69460546 |
| 74 | MP0002138_abnormal_hepatobiliary_system | 0.69101974 |
| 75 | MP0004510_myositis | 0.69026522 |
| 76 | MP0003828_pulmonary_edema | 0.67750160 |
| 77 | MP0003656_abnormal_erythrocyte_physiolo | 0.67513920 |
| 78 | MP0000604_amyloidosis | 0.66252364 |
| 79 | MP0005275_abnormal_skin_tensile | 0.65053552 |
| 80 | MP0003221_abnormal_cardiomyocyte_apopto | 0.64673540 |
| 81 | MP0008004_abnormal_stomach_pH | 0.63168285 |
| 82 | MP0009278_abnormal_bone_marrow | 0.62207461 |
| 83 | MP0005390_skeleton_phenotype | 0.61738435 |
| 84 | MP0000249_abnormal_blood_vessel | 0.58784306 |
| 85 | MP0005451_abnormal_body_composition | 0.58152214 |
| 86 | MP0002019_abnormal_tumor_incidence | 0.57905125 |
| 87 | MP0009765_abnormal_xenobiotic_induced | 0.56434812 |
| 88 | MP0000490_abnormal_crypts_of | 0.56043304 |
| 89 | MP0000343_altered_response_to | 0.55731493 |
| 90 | MP0005377_hearing/vestibular/ear_phenot | 0.53645379 |
| 91 | MP0003878_abnormal_ear_physiology | 0.53645379 |
| 92 | MP0005381_digestive/alimentary_phenotyp | 0.52575526 |
| 93 | MP0003091_abnormal_cell_migration | 0.52235227 |
| 94 | MP0003806_abnormal_nucleotide_metabolis | 0.50839430 |
| 95 | MP0005058_abnormal_lysosome_morphology | 0.48665278 |
| 96 | MP0001216_abnormal_epidermal_layer | 0.48450163 |
| 97 | MP0004130_abnormal_muscle_cell | 0.46887967 |
| 98 | MP0002095_abnormal_skin_pigmentation | 0.46804077 |
| 99 | MP0002638_abnormal_pupillary_reflex | 0.46758012 |
| 100 | MP0003453_abnormal_keratinocyte_physiol | 0.46193488 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Elevated erythrocyte sedimentation rate (HP:0003565) | 7.09501483 |
| 2 | Stomatitis (HP:0010280) | 5.55634266 |
| 3 | Myositis (HP:0100614) | 5.50358402 |
| 4 | T lymphocytopenia (HP:0005403) | 5.35138763 |
| 5 | Abnormality of T cell number (HP:0011839) | 5.27128611 |
| 6 | Eczematoid dermatitis (HP:0000976) | 4.89374544 |
| 7 | Autoimmune hemolytic anemia (HP:0001890) | 4.76477488 |
| 8 | Orchitis (HP:0100796) | 4.64550288 |
| 9 | Retrobulbar optic neuritis (HP:0100654) | 4.54165196 |
| 10 | Optic neuritis (HP:0100653) | 4.54165196 |
| 11 | Recurrent bacterial skin infections (HP:0005406) | 4.45652086 |
| 12 | Recurrent abscess formation (HP:0002722) | 4.23952718 |
| 13 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.96340509 |
| 14 | Recurrent cutaneous fungal infections (HP:0011370) | 3.96340509 |
| 15 | Abnormality of T cells (HP:0002843) | 3.87543803 |
| 16 | Keratoconjunctivitis sicca (HP:0001097) | 3.81310367 |
| 17 | Recurrent fungal infections (HP:0002841) | 3.78674329 |
| 18 | Severe combined immunodeficiency (HP:0004430) | 3.77467209 |
| 19 | IgG deficiency (HP:0004315) | 3.71177221 |
| 20 | Pulmonary infiltrates (HP:0002113) | 3.70284871 |
| 21 | Pustule (HP:0200039) | 3.63162953 |
| 22 | Increased IgM level (HP:0003496) | 3.60746401 |
| 23 | Vasculitis (HP:0002633) | 3.60043454 |
| 24 | Recurrent skin infections (HP:0001581) | 3.57419943 |
| 25 | Gangrene (HP:0100758) | 3.56448709 |
| 26 | Keratoconjunctivitis (HP:0001096) | 3.50460844 |
| 27 | Gastrointestinal infarctions (HP:0005244) | 3.49607826 |
| 28 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.47652639 |
| 29 | Leukocytosis (HP:0001974) | 3.43689823 |
| 30 | Abnormality of eosinophils (HP:0001879) | 3.38335334 |
| 31 | Hemoptysis (HP:0002105) | 3.37924485 |
| 32 | Mediastinal lymphadenopathy (HP:0100721) | 3.29987568 |
| 33 | Abnormality of macrophages (HP:0004311) | 3.26399289 |
| 34 | Meningitis (HP:0001287) | 3.23697114 |
| 35 | Recurrent bronchitis (HP:0002837) | 3.15165520 |
| 36 | Chronic obstructive pulmonary disease (HP:0006510) | 3.13779668 |
| 37 | Obstructive lung disease (HP:0006536) | 3.13779668 |
| 38 | Chest pain (HP:0100749) | 3.07993957 |
| 39 | Increased IgE level (HP:0003212) | 2.97438381 |
| 40 | Encephalitis (HP:0002383) | 2.93759998 |
| 41 | Urticaria (HP:0001025) | 2.87787518 |
| 42 | Combined immunodeficiency (HP:0005387) | 2.87192357 |
| 43 | Thyroiditis (HP:0100646) | 2.85579011 |
| 44 | Hypergammaglobulinemia (HP:0010702) | 2.85263616 |
| 45 | Pulmonary embolism (HP:0002204) | 2.76497286 |
| 46 | Eosinophilia (HP:0001880) | 2.76422882 |
| 47 | Abnormality of secondary sexual hair (HP:0009888) | 2.72708180 |
| 48 | Abnormality of the axillary hair (HP:0100134) | 2.72708180 |
| 49 | Abnormality of the pleura (HP:0002103) | 2.71933058 |
| 50 | Abnormality of T cell physiology (HP:0011840) | 2.67754857 |
| 51 | Chronic diarrhea (HP:0002028) | 2.64000338 |
| 52 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.62023610 |
| 53 | Abnormality of the prostate (HP:0008775) | 2.61179536 |
| 54 | Gingivitis (HP:0000230) | 2.58959118 |
| 55 | Granulocytopenia (HP:0001913) | 2.55634316 |
| 56 | Stomach cancer (HP:0012126) | 2.55160881 |
| 57 | Erythema (HP:0010783) | 2.52851241 |
| 58 | Peritonitis (HP:0002586) | 2.50175228 |
| 59 | Spontaneous hematomas (HP:0007420) | 2.47101550 |
| 60 | Thick nail (HP:0001805) | 2.46782092 |
| 61 | Inflammation of the large intestine (HP:0002037) | 2.45217327 |
| 62 | Epistaxis (HP:0000421) | 2.37085060 |
| 63 | Arterial thrombosis (HP:0004420) | 2.35861475 |
| 64 | Recurrent viral infections (HP:0004429) | 2.33758323 |
| 65 | IgM deficiency (HP:0002850) | 2.32644047 |
| 66 | Abnormality of nail color (HP:0100643) | 2.26427474 |
| 67 | Polyneuropathy (HP:0001271) | 2.24227868 |
| 68 | Gastrointestinal inflammation (HP:0004386) | 2.22755131 |
| 69 | Ureteral stenosis (HP:0000071) | 2.22419164 |
| 70 | Skin rash (HP:0000988) | 2.22367831 |
| 71 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.18292749 |
| 72 | Ureteral obstruction (HP:0006000) | 2.17020335 |
| 73 | Colitis (HP:0002583) | 2.14302309 |
| 74 | Panhypogammaglobulinemia (HP:0003139) | 2.14002394 |
| 75 | Gingival bleeding (HP:0000225) | 2.13174001 |
| 76 | Hypoplasia of the thymus (HP:0000778) | 2.12197037 |
| 77 | Abnormality of the pericardium (HP:0001697) | 2.11310137 |
| 78 | Alveolar cell carcinoma (HP:0006519) | 2.09211338 |
| 79 | Sepsis (HP:0100806) | 2.07741800 |
| 80 | Glomerulopathy (HP:0100820) | 2.05572870 |
| 81 | Joint swelling (HP:0001386) | 2.03374760 |
| 82 | Skin ulcer (HP:0200042) | 2.03304901 |
| 83 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.03024159 |
| 84 | Autoimmune thrombocytopenia (HP:0001973) | 2.01236747 |
| 85 | Anorexia (HP:0002039) | 2.00007723 |
| 86 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.98450174 |
| 87 | Neoplasm of the tracheobronchial system (HP:0100552) | 1.96845504 |
| 88 | Fatigue (HP:0012378) | 1.96214386 |
| 89 | Onycholysis (HP:0001806) | 1.95930520 |
| 90 | Woolly hair (HP:0002224) | 1.93991313 |
| 91 | Agammaglobulinemia (HP:0004432) | 1.92136956 |
| 92 | Keratitis (HP:0000491) | 1.91593085 |
| 93 | Pili torti (HP:0003777) | 1.91037211 |
| 94 | Thrombophlebitis (HP:0004418) | 1.90384092 |
| 95 | Lymphopenia (HP:0001888) | 1.89413995 |
| 96 | Pruritus (HP:0000989) | 1.88286700 |
| 97 | Hypochromic anemia (HP:0001931) | 1.86388075 |
| 98 | Episodic fever (HP:0001954) | 1.85664120 |
| 99 | Aplastic anemia (HP:0001915) | 1.84088832 |
| 100 | Petechiae (HP:0000967) | 1.84036580 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 6.18845117 |
| 2 | TYK2 | 3.55267722 |
| 3 | MAP4K1 | 3.12923812 |
| 4 | SCYL2 | 2.95792948 |
| 5 | JAK1 | 2.69966386 |
| 6 | FES | 2.62619497 |
| 7 | JAK3 | 2.59876545 |
| 8 | GRK6 | 2.43725220 |
| 9 | IRAK4 | 2.38930648 |
| 10 | TAOK3 | 2.33329407 |
| 11 | RIPK4 | 2.32290900 |
| 12 | TEC | 2.18302130 |
| 13 | ITK | 2.16428433 |
| 14 | CSK | 2.13179755 |
| 15 | IKBKE | 2.09254677 |
| 16 | MAP3K14 | 1.93409646 |
| 17 | FGFR4 | 1.91539503 |
| 18 | BTK | 1.87573679 |
| 19 | CDK19 | 1.82943089 |
| 20 | BLK | 1.82781767 |
| 21 | BMPR2 | 1.80301491 |
| 22 | NLK | 1.75693816 |
| 23 | KIT | 1.69784203 |
| 24 | ZAP70 | 1.68830645 |
| 25 | FGR | 1.59218658 |
| 26 | FGFR3 | 1.57900470 |
| 27 | NUAK1 | 1.56629249 |
| 28 | SYK | 1.51117403 |
| 29 | LCK | 1.48544580 |
| 30 | PDK2 | 1.47961034 |
| 31 | JAK2 | 1.47931750 |
| 32 | CSF1R | 1.46490864 |
| 33 | ERN1 | 1.43068205 |
| 34 | CAMKK2 | 1.38739533 |
| 35 | HCK | 1.36411742 |
| 36 | MAP3K13 | 1.35817519 |
| 37 | SIK3 | 1.35116064 |
| 38 | MAP2K3 | 1.31935662 |
| 39 | LYN | 1.24070981 |
| 40 | TBK1 | 1.23495143 |
| 41 | IKBKB | 1.08640862 |
| 42 | MARK3 | 1.08609412 |
| 43 | MAP3K1 | 1.03517820 |
| 44 | EPHB1 | 1.02568596 |
| 45 | AKT3 | 0.95161980 |
| 46 | MAP3K3 | 0.93666243 |
| 47 | TNK2 | 0.93547440 |
| 48 | NEK9 | 0.91768600 |
| 49 | LRRK2 | 0.88689475 |
| 50 | HIPK2 | 0.87577701 |
| 51 | RPS6KA4 | 0.85158142 |
| 52 | WNK1 | 0.78648364 |
| 53 | TIE1 | 0.75531266 |
| 54 | MST4 | 0.73668407 |
| 55 | MAP3K6 | 0.72824106 |
| 56 | MAP3K12 | 0.69890814 |
| 57 | MAP2K6 | 0.68707533 |
| 58 | SGK2 | 0.67714811 |
| 59 | PIK3CG | 0.67365210 |
| 60 | MAPKAPK3 | 0.62365815 |
| 61 | IRAK1 | 0.61982489 |
| 62 | TAOK1 | 0.61973316 |
| 63 | LATS1 | 0.60637102 |
| 64 | EPHA3 | 0.60597907 |
| 65 | PIM1 | 0.57841502 |
| 66 | FYN | 0.55354921 |
| 67 | NEK6 | 0.54974181 |
| 68 | PDK1 | 0.53150767 |
| 69 | PRPF4B | 0.53021485 |
| 70 | PRKCQ | 0.50524073 |
| 71 | CLK1 | 0.50486235 |
| 72 | SGK3 | 0.49649477 |
| 73 | ADRBK2 | 0.46632128 |
| 74 | TLK1 | 0.46225863 |
| 75 | STK10 | 0.45611277 |
| 76 | GRK7 | 0.44571030 |
| 77 | STK24 | 0.44117937 |
| 78 | STK38 | 0.42945042 |
| 79 | PTK2B | 0.40625986 |
| 80 | FRK | 0.40238698 |
| 81 | MAPKAPK2 | 0.37753932 |
| 82 | MATK | 0.37265211 |
| 83 | MAPK12 | 0.35546824 |
| 84 | CAMKK1 | 0.34596313 |
| 85 | STK38L | 0.34348490 |
| 86 | SGK494 | 0.33627538 |
| 87 | SGK223 | 0.33627538 |
| 88 | TRPM7 | 0.32024643 |
| 89 | ABL1 | 0.31928713 |
| 90 | YES1 | 0.30275562 |
| 91 | EGFR | 0.29814264 |
| 92 | MAPK11 | 0.28033048 |
| 93 | IGF1R | 0.27953913 |
| 94 | PDPK1 | 0.27569903 |
| 95 | CHUK | 0.27252040 |
| 96 | TYRO3 | 0.26957773 |
| 97 | RPS6KA5 | 0.26575453 |
| 98 | MAP3K2 | 0.24999507 |
| 99 | TAOK2 | 0.23861539 |
| 100 | STK11 | 0.19080922 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 4.05158416 |
| 2 | Allograft rejection_Homo sapiens_hsa05330 | 3.88489002 |
| 3 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.60242916 |
| 4 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 3.29220101 |
| 5 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.26941256 |
| 6 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 3.10553704 |
| 7 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.97960299 |
| 8 | Leishmaniasis_Homo sapiens_hsa05140 | 2.92416555 |
| 9 | Asthma_Homo sapiens_hsa05310 | 2.90332576 |
| 10 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.60978090 |
| 11 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.34967270 |
| 12 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 2.31605599 |
| 13 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.26352758 |
| 14 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.17492449 |
| 15 | Measles_Homo sapiens_hsa05162 | 2.15073513 |
| 16 | Viral myocarditis_Homo sapiens_hsa05416 | 2.05187039 |
| 17 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.02959558 |
| 18 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.93848139 |
| 19 | Tuberculosis_Homo sapiens_hsa05152 | 1.85097382 |
| 20 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.74732507 |
| 21 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.64929272 |
| 22 | Influenza A_Homo sapiens_hsa05164 | 1.61327331 |
| 23 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.55376608 |
| 24 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.50955818 |
| 25 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.49563885 |
| 26 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.48122341 |
| 27 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.46673177 |
| 28 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.46317427 |
| 29 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.45823287 |
| 30 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.34741876 |
| 31 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.34112070 |
| 32 | Malaria_Homo sapiens_hsa05144 | 1.33834077 |
| 33 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.29775722 |
| 34 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.15889331 |
| 35 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.08443756 |
| 36 | Legionellosis_Homo sapiens_hsa05134 | 1.03624268 |
| 37 | Hepatitis B_Homo sapiens_hsa05161 | 1.01400939 |
| 38 | Phagosome_Homo sapiens_hsa04145 | 0.99032145 |
| 39 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.95889472 |
| 40 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.94948751 |
| 41 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.93288748 |
| 42 | Platelet activation_Homo sapiens_hsa04611 | 0.93213261 |
| 43 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.89249378 |
| 44 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.77653974 |
| 45 | Hepatitis C_Homo sapiens_hsa05160 | 0.75258514 |
| 46 | Pertussis_Homo sapiens_hsa05133 | 0.70551354 |
| 47 | Apoptosis_Homo sapiens_hsa04210 | 0.70354103 |
| 48 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.61829130 |
| 49 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.61681753 |
| 50 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.59365205 |
| 51 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.57290166 |
| 52 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.55096016 |
| 53 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.53086512 |
| 54 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.53052423 |
| 55 | ABC transporters_Homo sapiens_hsa02010 | 0.52768496 |
| 56 | HTLV-I infection_Homo sapiens_hsa05166 | 0.52645098 |
| 57 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.51586275 |
| 58 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.50726838 |
| 59 | Shigellosis_Homo sapiens_hsa05131 | 0.49995501 |
| 60 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.49066136 |
| 61 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.48629483 |
| 62 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.46389756 |
| 63 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.44083886 |
| 64 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.42755155 |
| 65 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.42711759 |
| 66 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.42575870 |
| 67 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.39208486 |
| 68 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.38035345 |
| 69 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.36561151 |
| 70 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.36254730 |
| 71 | Salmonella infection_Homo sapiens_hsa05132 | 0.36151138 |
| 72 | Endocytosis_Homo sapiens_hsa04144 | 0.35096192 |
| 73 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.33637167 |
| 74 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.33333302 |
| 75 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.32123111 |
| 76 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.28032365 |
| 77 | Circadian rhythm_Homo sapiens_hsa04710 | 0.27773261 |
| 78 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.27172788 |
| 79 | Amoebiasis_Homo sapiens_hsa05146 | 0.26610126 |
| 80 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.25682649 |
| 81 | Insulin resistance_Homo sapiens_hsa04931 | 0.25147241 |
| 82 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.24517085 |
| 83 | Lysosome_Homo sapiens_hsa04142 | 0.24481753 |
| 84 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.23637631 |
| 85 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.23414309 |
| 86 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.22783195 |
| 87 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.20030686 |
| 88 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.19401709 |
| 89 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.18495906 |
| 90 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.18130732 |
| 91 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.17072842 |
| 92 | Olfactory transduction_Homo sapiens_hsa04740 | 0.15475178 |
| 93 | Thyroid cancer_Homo sapiens_hsa05216 | 0.15135683 |
| 94 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.15075559 |
| 95 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.14585738 |
| 96 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.12703255 |
| 97 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.12170887 |
| 98 | Colorectal cancer_Homo sapiens_hsa05210 | 0.12158953 |
| 99 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.11640504 |
| 100 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.11107451 |

