CBARP

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)6.42850627
2synaptic vesicle maturation (GO:0016188)6.20798606
3locomotory exploration behavior (GO:0035641)5.81000608
4positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.79225585
5vocalization behavior (GO:0071625)5.51798425
6positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.44296981
7synaptic vesicle exocytosis (GO:0016079)5.35160525
8regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.25920956
9regulation of synaptic vesicle exocytosis (GO:2000300)5.17043208
10glutamate secretion (GO:0014047)5.06971615
11regulation of glutamate receptor signaling pathway (GO:1900449)4.98309543
12neuron cell-cell adhesion (GO:0007158)4.77736950
13protein localization to synapse (GO:0035418)4.77458515
14neurotransmitter secretion (GO:0007269)4.61925102
15ionotropic glutamate receptor signaling pathway (GO:0035235)4.61031987
16regulation of synaptic vesicle transport (GO:1902803)4.59580025
17exploration behavior (GO:0035640)4.57544636
18synaptic vesicle docking involved in exocytosis (GO:0016081)4.54272598
19regulation of neuronal synaptic plasticity (GO:0048168)4.48611170
20layer formation in cerebral cortex (GO:0021819)4.45280228
21regulation of long-term neuronal synaptic plasticity (GO:0048169)4.42067760
22neuronal action potential propagation (GO:0019227)4.41630427
23dendritic spine morphogenesis (GO:0060997)4.30021468
24regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.10331554
25positive regulation of synaptic transmission, GABAergic (GO:0032230)4.06801354
26gamma-aminobutyric acid transport (GO:0015812)4.05936842
27regulation of synapse structural plasticity (GO:0051823)4.04040719
28synaptic transmission, glutamatergic (GO:0035249)4.02919192
29proline transport (GO:0015824)4.00473800
30glutamate receptor signaling pathway (GO:0007215)3.98615250
31neuromuscular process controlling posture (GO:0050884)3.84554972
32planar cell polarity pathway involved in neural tube closure (GO:0090179)3.83184380
33activation of protein kinase A activity (GO:0034199)3.81990429
34long-term memory (GO:0007616)3.78942832
35neurotransmitter transport (GO:0006836)3.76968344
36positive regulation of membrane potential (GO:0045838)3.76954955
37neuron-neuron synaptic transmission (GO:0007270)3.75546467
38neuron recognition (GO:0008038)3.74970161
39cellular potassium ion homeostasis (GO:0030007)3.74358853
40neurotransmitter-gated ion channel clustering (GO:0072578)3.68663240
41regulation of excitatory postsynaptic membrane potential (GO:0060079)3.59345096
42transmission of nerve impulse (GO:0019226)3.56886465
43positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.56097816
44cytoskeletal anchoring at plasma membrane (GO:0007016)3.55809340
45axonal fasciculation (GO:0007413)3.52447029
46sodium ion export (GO:0071436)3.52378297
47regulation of vesicle fusion (GO:0031338)3.50156539
48postsynaptic membrane organization (GO:0001941)3.50102330
49neuromuscular process controlling balance (GO:0050885)3.49220524
50cell-cell junction maintenance (GO:0045217)3.49113306
51regulation of neurotransmitter levels (GO:0001505)3.48884285
52regulation of postsynaptic membrane potential (GO:0060078)3.47106247
53membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.46742227
54regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.44739048
55regulation of synaptic plasticity (GO:0048167)3.43669331
56regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.40619326
57synaptic vesicle endocytosis (GO:0048488)3.37940747
58cerebellar Purkinje cell differentiation (GO:0021702)3.36809340
59regulation of neurotransmitter secretion (GO:0046928)3.36546500
60establishment of mitochondrion localization (GO:0051654)3.35334407
61mitochondrion transport along microtubule (GO:0047497)3.34568792
62establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.34568792
63regulation of dendritic spine morphogenesis (GO:0061001)3.32796470
64gamma-aminobutyric acid signaling pathway (GO:0007214)3.30178889
65auditory behavior (GO:0031223)3.28792591
66neuronal ion channel clustering (GO:0045161)3.27407641
67positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.26727220
68glycine transport (GO:0015816)3.26589738
69negative regulation of catenin import into nucleus (GO:0035414)3.25194474
70cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.24764587
71dichotomous subdivision of an epithelial terminal unit (GO:0060600)3.24630789
72regulation of glutamate secretion (GO:0014048)3.22734176
73response to auditory stimulus (GO:0010996)3.22351109
74prepulse inhibition (GO:0060134)3.20280156
75mating behavior (GO:0007617)3.20049413
76intraspecies interaction between organisms (GO:0051703)3.19476166
77social behavior (GO:0035176)3.19476166
78vesicle transport along microtubule (GO:0047496)3.19383511
79cerebellar granule cell differentiation (GO:0021707)3.18734368
80cerebellar Purkinje cell layer development (GO:0021680)3.17982027
81positive regulation of synapse maturation (GO:0090129)3.17384215
82cell communication by electrical coupling (GO:0010644)3.15986574
83G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.14002872
84long-term synaptic potentiation (GO:0060291)3.13907993
85regulation of synaptic transmission, glutamatergic (GO:0051966)3.13167954
86negative regulation of synaptic transmission, GABAergic (GO:0032229)3.13031196
87regulation of neurotransmitter transport (GO:0051588)3.12979547
88positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.12668583
89dendrite morphogenesis (GO:0048813)3.11940230
90negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.11822685
91positive regulation of neurotransmitter transport (GO:0051590)3.11687798
92regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.11437240
93semaphorin-plexin signaling pathway (GO:0071526)3.06133030
94membrane hyperpolarization (GO:0060081)3.05859223
95membrane depolarization during action potential (GO:0086010)3.04341146
96membrane depolarization (GO:0051899)3.03750083
97synapse assembly (GO:0007416)3.02434018
98regulation of synaptic transmission, GABAergic (GO:0032228)3.02352411
99regulation of female receptivity (GO:0045924)3.01953025
100learning (GO:0007612)3.01824173
101positive regulation of neurotransmitter secretion (GO:0001956)3.01528554
102protein retention in ER lumen (GO:0006621)3.01112947
103axon extension (GO:0048675)2.99969226
104positive regulation of dendritic spine development (GO:0060999)2.99924868
105cell migration in hindbrain (GO:0021535)2.97819059
106positive regulation of synaptic transmission (GO:0050806)2.97562102
107regulation of synaptic transmission (GO:0050804)2.96701065
108dendritic spine organization (GO:0097061)2.94957939
109neuromuscular process (GO:0050905)2.94399316
110innervation (GO:0060384)2.94209914
111presynaptic membrane assembly (GO:0097105)2.92677099
112synaptic transmission (GO:0007268)2.92630040
113response to histamine (GO:0034776)2.92108286
114regulation of NFAT protein import into nucleus (GO:0051532)2.91532649
115dopamine receptor signaling pathway (GO:0007212)2.81955552
116positive regulation of synapse assembly (GO:0051965)2.78071442
117convergent extension (GO:0060026)2.72861203
118maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.72562473
119neuron projection extension (GO:1990138)2.71720703
120negative regulation of dendrite morphogenesis (GO:0050774)2.71059457
121pyrimidine nucleobase catabolic process (GO:0006208)2.69978833
122amino acid import (GO:0043090)2.63493113
123regulation of axon extension involved in axon guidance (GO:0048841)2.63187504
124protein localization to endosome (GO:0036010)2.62656797
125neuron projection regeneration (GO:0031102)2.62098557
126presynaptic membrane organization (GO:0097090)2.60667041
127cell junction maintenance (GO:0034331)2.58955193
128cochlea morphogenesis (GO:0090103)2.57063762
129respiratory system process (GO:0003016)2.56787230
130axon regeneration (GO:0031103)2.56640825
131Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.56331335
132axon extension involved in axon guidance (GO:0048846)2.55091902
133neuron projection extension involved in neuron projection guidance (GO:1902284)2.55091902
134cranial nerve morphogenesis (GO:0021602)2.50311288
135positive regulation of axon extension (GO:0045773)2.49642510
136adherens junction assembly (GO:0034333)2.49172072
137positive regulation of dendritic spine morphogenesis (GO:0061003)2.48632678
138skeletal muscle organ development (GO:0060538)2.47279028
139regulation of early endosome to late endosome transport (GO:2000641)2.46894040
140regulation of axon guidance (GO:1902667)2.44444331
141cellular component maintenance (GO:0043954)2.42770241
142regulation of mammary gland epithelial cell proliferation (GO:0033599)2.40268552
143response to dietary excess (GO:0002021)2.40095697
144positive regulation of dendrite development (GO:1900006)2.38317361
145protein targeting to plasma membrane (GO:0072661)2.38084471
146negative regulation of microtubule polymerization (GO:0031115)2.38049153
147establishment of apical/basal cell polarity (GO:0035089)2.37691980
148apical protein localization (GO:0045176)2.36802953
149regulation of establishment of planar polarity (GO:0090175)2.35937521
150regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.34378634
151adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.33120144

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.47592525
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.38808558
3JARID2_20064375_ChIP-Seq_MESCs_Mouse3.21630076
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.20852698
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.12555794
6GBX2_23144817_ChIP-Seq_PC3_Human3.05782366
7REST_21632747_ChIP-Seq_MESCs_Mouse2.94742932
8JARID2_20075857_ChIP-Seq_MESCs_Mouse2.83398041
9RNF2_18974828_ChIP-Seq_MESCs_Mouse2.83047631
10EZH2_18974828_ChIP-Seq_MESCs_Mouse2.83047631
11RARB_27405468_Chip-Seq_BRAIN_Mouse2.79581763
12SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.68929458
13EZH2_27304074_Chip-Seq_ESCs_Mouse2.66626597
14SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.65866221
15THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.65193239
16MTF2_20144788_ChIP-Seq_MESCs_Mouse2.63989437
17DROSHA_22980978_ChIP-Seq_HELA_Human2.60578103
18SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.58406494
19SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.58387943
20CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.47510345
21LXR_22292898_ChIP-Seq_THP-1_Human2.46316647
22SUZ12_27294783_Chip-Seq_ESCs_Mouse2.45965681
23REST_18959480_ChIP-ChIP_MESCs_Mouse2.44498198
24EZH2_27294783_Chip-Seq_ESCs_Mouse2.42858622
25IKZF1_21737484_ChIP-ChIP_HCT116_Human2.38749493
26NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.34030865
27EED_16625203_ChIP-ChIP_MESCs_Mouse2.33623898
28ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.28793011
29RNF2_27304074_Chip-Seq_ESCs_Mouse2.28057690
30TP63_17297297_ChIP-ChIP_HaCaT_Human2.20449804
31RARG_19884340_ChIP-ChIP_MEFs_Mouse2.16282263
32EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.13892716
33MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.13310575
34KDM2B_26808549_Chip-Seq_SUP-B15_Human2.12660155
35ERG_21242973_ChIP-ChIP_JURKAT_Human1.81836040
36ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.78909141
37ELK3_25401928_ChIP-Seq_HUVEC_Human1.78601673
38AR_21572438_ChIP-Seq_LNCaP_Human1.75542929
39KDM2B_26808549_Chip-Seq_DND41_Human1.71517193
40UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.67522733
41TRIM28_21343339_ChIP-Seq_HEK293_Human1.66156547
42CTBP2_25329375_ChIP-Seq_LNCAP_Human1.65502706
43RACK7_27058665_Chip-Seq_MCF-7_Human1.57490204
44GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.56903355
45EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.56132963
46KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.54875233
47SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.52743929
48ZNF274_21170338_ChIP-Seq_K562_Hela1.50688318
49CTBP1_25329375_ChIP-Seq_LNCAP_Human1.49083430
50ESR2_21235772_ChIP-Seq_MCF-7_Human1.47625922
51TET1_21451524_ChIP-Seq_MESCs_Mouse1.47436763
52TAF15_26573619_Chip-Seq_HEK293_Human1.46174123
53RING1B_27294783_Chip-Seq_ESCs_Mouse1.45325885
54RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.44150310
55SMAD4_21799915_ChIP-Seq_A2780_Human1.43786515
56PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.43454484
57DNAJC2_21179169_ChIP-ChIP_NT2_Human1.43117107
58SRY_22984422_ChIP-ChIP_TESTIS_Rat1.42632261
59KDM2B_26808549_Chip-Seq_JURKAT_Human1.42260933
60SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.42094374
61ZNF263_19887448_ChIP-Seq_K562_Human1.38793808
62ESR1_15608294_ChIP-ChIP_MCF-7_Human1.36595832
63PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.34042565
64TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.33941461
65RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.33613561
66P68_20966046_ChIP-Seq_HELA_Human1.33263175
67SMC4_20622854_ChIP-Seq_HELA_Human1.32604599
68ZFP281_18757296_ChIP-ChIP_E14_Mouse1.30901633
69P300_27058665_Chip-Seq_ZR-75-30cells_Human1.29286109
70SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.28935451
71CREB1_26743006_Chip-Seq_LNCaP_Human1.28862703
72SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.28099057
73TP53_22127205_ChIP-Seq_IMR90_Human1.27962042
74SA1_27219007_Chip-Seq_ERYTHROID_Human1.27788490
75NR3C1_23031785_ChIP-Seq_PC12_Mouse1.26398136
76KDM2B_26808549_Chip-Seq_K562_Human1.25995393
77PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.22859132
78DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.21871581
79BMI1_23680149_ChIP-Seq_NPCS_Mouse1.21274714
80NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.20749754
81SOX2_21211035_ChIP-Seq_LN229_Gbm1.20685913
82ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.20642717
83EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.20433278
84TCF7_22412390_ChIP-Seq_EML_Mouse1.19949270
85CTCF_27219007_Chip-Seq_ERYTHROID_Human1.19452963
86RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.19111692
87CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.18722591
88RING1B_27294783_Chip-Seq_NPCs_Mouse1.18442170
89SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.17625657
90MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.17432998
91WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.15341593
92CBX2_27304074_Chip-Seq_ESCs_Mouse1.14614165
93WT1_25993318_ChIP-Seq_PODOCYTE_Human1.14541468
94AR_19668381_ChIP-Seq_PC3_Human1.14105264
95TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.13802571
96SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.11418503
97SMAD3_21741376_ChIP-Seq_EPCs_Human1.11228184
98CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.11031690
99CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.10406227
100IGF1R_20145208_ChIP-Seq_DFB_Human1.09053405
101P300_19829295_ChIP-Seq_ESCs_Human1.09042740
102VDR_21846776_ChIP-Seq_THP-1_Human1.08196454
103CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.08176503
104AR_25329375_ChIP-Seq_VCAP_Human1.08010355
105TP53_23651856_ChIP-Seq_MEFs_Mouse1.06100391
106POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.05220690
107CLOCK_20551151_ChIP-Seq_293T_Human1.05148031
108KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.04699188
109RNF2_27304074_Chip-Seq_NSC_Mouse1.04392328
110SOX3_22085726_ChIP-Seq_NPCs_Mouse1.04138480
111TOP2B_26459242_ChIP-Seq_MCF-7_Human1.03057820
112STAT3_23295773_ChIP-Seq_U87_Human1.02986545
113ZFP57_27257070_Chip-Seq_ESCs_Mouse1.02532222
114TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.01955110
115CTCF_27219007_Chip-Seq_Bcells_Human1.00714367
116NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.00649313
117CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.00636106
118P53_22127205_ChIP-Seq_FIBROBLAST_Human0.99824384
119GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.98489715
120RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.98270106
121MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.97635637
122NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.97151645
123SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.96639975
124TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.95769581
125SMAD3_21741376_ChIP-Seq_ESCs_Human0.95700761
126CDX2_19796622_ChIP-Seq_MESCs_Mouse0.94744029
127GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94372757
128SMAD_19615063_ChIP-ChIP_OVARY_Human0.94134923
129STAT6_21828071_ChIP-Seq_BEAS2B_Human0.94035230
130TET1_21490601_ChIP-Seq_MESCs_Mouse0.93818060
131YAP1_20516196_ChIP-Seq_MESCs_Mouse0.93736423
132OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.93566169
133AHR_22903824_ChIP-Seq_MCF-7_Human0.91053161
134SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.90705424
135TCF4_23295773_ChIP-Seq_U87_Human0.90344923
136ARNT_22903824_ChIP-Seq_MCF-7_Human0.90103374
137ZFP281_27345836_Chip-Seq_ESCs_Mouse0.89898454
138ZNF217_24962896_ChIP-Seq_MCF-7_Human0.89850998
139SMAD4_21741376_ChIP-Seq_HESCs_Human0.89190170
140OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.87882121
141PIAS1_25552417_ChIP-Seq_VCAP_Human0.87807996
142TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.87600371
143RUNX2_22187159_ChIP-Seq_PCA_Human0.85856795
144SMAD3_21741376_ChIP-Seq_HESCs_Human0.84246973
145TP53_20018659_ChIP-ChIP_R1E_Mouse0.82348391
146CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.82154855
147PRDM14_20953172_ChIP-Seq_ESCs_Human0.81259899
148NR3C1_21868756_ChIP-Seq_MCF10A_Human0.81097367
149VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.79554391
150TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.77685349
151KLF4_19829295_ChIP-Seq_ESCs_Human0.75971038

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.29694125
2MP0003880_abnormal_central_pattern4.85761321
3MP0003635_abnormal_synaptic_transmissio4.12508787
4MP0004270_analgesia3.55496452
5MP0009745_abnormal_behavioral_response3.40105531
6MP0002063_abnormal_learning/memory/cond3.23400515
7MP0005423_abnormal_somatic_nervous3.16345839
8MP0002064_seizures3.15215280
9MP0001968_abnormal_touch/_nociception3.14611953
10MP0005257_abnormal_intraocular_pressure3.04161440
11MP0009046_muscle_twitch2.93735672
12MP0003705_abnormal_hypodermis_morpholog2.84306471
13MP0002572_abnormal_emotion/affect_behav2.72854674
14MP0002822_catalepsy2.70813153
15MP0002734_abnormal_mechanical_nocicepti2.61918176
16MP0002272_abnormal_nervous_system2.53637424
17MP0001486_abnormal_startle_reflex2.42739191
18MP0001501_abnormal_sleep_pattern2.33578689
19MP0002736_abnormal_nociception_after2.21148330
20MP0003122_maternal_imprinting2.20692327
21MP0010030_abnormal_orbit_morphology2.19097875
22MP0002733_abnormal_thermal_nociception2.18624102
23MP0005645_abnormal_hypothalamus_physiol2.17093555
24MP0001440_abnormal_grooming_behavior2.16692917
25MP0006276_abnormal_autonomic_nervous2.13929926
26MP0002735_abnormal_chemical_nociception2.06327507
27MP0001970_abnormal_pain_threshold2.05725018
28MP0000566_synostosis2.04977080
29MP0002909_abnormal_adrenal_gland1.99921488
30MP0002249_abnormal_larynx_morphology1.94805671
31MP0009780_abnormal_chondrocyte_physiolo1.93921849
32MP0002067_abnormal_sensory_capabilities1.88324203
33MP0000537_abnormal_urethra_morphology1.83546277
34MP0002184_abnormal_innervation1.82919058
35MP0002557_abnormal_social/conspecific_i1.80987130
36MP0003329_amyloid_beta_deposits1.80546082
37MP0004858_abnormal_nervous_system1.76449808
38MP0004811_abnormal_neuron_physiology1.75270694
39MP0000778_abnormal_nervous_system1.72891335
40MP0008569_lethality_at_weaning1.72487464
41MP0005386_behavior/neurological_phenoty1.68718156
42MP0004924_abnormal_behavior1.68718156
43MP0005646_abnormal_pituitary_gland1.62074371
44MP0003787_abnormal_imprinting1.59670803
45MP0000579_abnormal_nail_morphology1.57905684
46MP0000955_abnormal_spinal_cord1.57588409
47MP0001984_abnormal_olfaction1.54581479
48MP0000534_abnormal_ureter_morphology1.45377135
49MP0003879_abnormal_hair_cell1.44957983
50MP0002089_abnormal_postnatal_growth/wei1.42809549
51MP0005076_abnormal_cell_differentiation1.42705454
52MP0009053_abnormal_anal_canal1.42512360
53MP0001529_abnormal_vocalization1.42457528
54MP0002882_abnormal_neuron_morphology1.41624538
55MP0001502_abnormal_circadian_rhythm1.41073217
56MP0002066_abnormal_motor_capabilities/c1.41015679
57MP0004142_abnormal_muscle_tone1.40300114
58MP0004885_abnormal_endolymph1.36906958
59MP0003283_abnormal_digestive_organ1.33440918
60MP0003942_abnormal_urinary_system1.32921695
61MP0001905_abnormal_dopamine_level1.32284396
62MP0008961_abnormal_basal_metabolism1.30622626
63MP0001849_ear_inflammation1.25897696
64MP0003633_abnormal_nervous_system1.25326743
65MP0008438_abnormal_cutaneous_collagen1.23701044
66MP0000049_abnormal_middle_ear1.22029709
67MP0000013_abnormal_adipose_tissue1.14468886
68MP0006292_abnormal_olfactory_placode1.13679932
69MP0000428_abnormal_craniofacial_morphol1.13676193
70MP0003385_abnormal_body_wall1.12912186
71MP0004272_abnormal_basement_membrane1.12564435
72MP0000751_myopathy1.10253708
73MP0002152_abnormal_brain_morphology1.09316066
74MP0003123_paternal_imprinting1.06378758
75MP0003631_nervous_system_phenotype1.01328476
76MP0002069_abnormal_eating/drinking_beha1.00300652
77MP0008872_abnormal_physiological_respon0.99502381
78MP0010386_abnormal_urinary_bladder0.99345879
79MP0005058_abnormal_lysosome_morphology0.99321072
80MP0001346_abnormal_lacrimal_gland0.97524811
81MP0004145_abnormal_muscle_electrophysio0.96955063
82MP0002697_abnormal_eye_size0.95729464
83MP0002229_neurodegeneration0.95557869
84MP0009250_abnormal_appendicular_skeleto0.93532397
85MP0000733_abnormal_muscle_development0.93122685
86MP0000631_abnormal_neuroendocrine_gland0.92345904
87MP0002116_abnormal_craniofacial_bone0.91155259
88MP0000678_abnormal_parathyroid_gland0.90565502
89MP0005508_abnormal_skeleton_morphology0.90262602
90MP0000003_abnormal_adipose_tissue0.89972123
91MP0001188_hyperpigmentation0.89621687
92MP0002653_abnormal_ependyma_morphology0.88452876
93MP0004510_myositis0.86682506
94MP0004133_heterotaxia0.84822638
95MP0002081_perinatal_lethality0.84774458
96MP0001177_atelectasis0.84701009
97MP0004742_abnormal_vestibular_system0.84674395
98MP0003634_abnormal_glial_cell0.84614762
99MP0005499_abnormal_olfactory_system0.83815300
100MP0005394_taste/olfaction_phenotype0.83815300
101MP0008874_decreased_physiological_sensi0.83784348
102MP0003121_genomic_imprinting0.83715228
103MP0005535_abnormal_body_temperature0.83329450
104MP0003119_abnormal_digestive_system0.82967290
105MP0003938_abnormal_ear_development0.82516183
106MP0009384_cardiac_valve_regurgitation0.81837182
107MP0002638_abnormal_pupillary_reflex0.79815880
108MP0003279_aneurysm0.79571148
109MP0003075_altered_response_to0.78704543
110MP0000462_abnormal_digestive_system0.77506249
111MP0004085_abnormal_heartbeat0.75488139
112MP0005551_abnormal_eye_electrophysiolog0.75402004
113MP0003690_abnormal_glial_cell0.75190233
114MP0000762_abnormal_tongue_morphology0.75004328
115MP0002752_abnormal_somatic_nervous0.74450879
116MP0001958_emphysema0.73828195
117MP0002092_abnormal_eye_morphology0.73330937
118MP0003091_abnormal_cell_migration0.73144942
119MP0001963_abnormal_hearing_physiology0.71454963
120MP0009672_abnormal_birth_weight0.71425234
121MP0000920_abnormal_myelination0.71039656
122MP0000604_amyloidosis0.70744351
123MP0003115_abnormal_respiratory_system0.70485325
124MP0004233_abnormal_muscle_weight0.70001041
125MP0006072_abnormal_retinal_apoptosis0.69505991
126MP0005623_abnormal_meninges_morphology0.69244533
127MP0003137_abnormal_impulse_conducting0.65938626
128MP0001664_abnormal_digestion0.65093783
129MP0000569_abnormal_digit_pigmentation0.65051137
130MP0003632_abnormal_nervous_system0.64581152
131MP0002837_dystrophic_cardiac_calcinosis0.64409727
132MP0005167_abnormal_blood-brain_barrier0.62169347
133MP0002090_abnormal_vision0.61273890
134MP0001299_abnormal_eye_distance/0.60874238
135MP0001485_abnormal_pinna_reflex0.59875948
136MP0001943_abnormal_respiration0.58254916
137MP0010234_abnormal_vibrissa_follicle0.56401876
138MP0003861_abnormal_nervous_system0.54940864
139MP0003172_abnormal_lysosome_physiology0.54894049
140MP0005409_darkened_coat_color0.53802386
141MP0010769_abnormal_survival0.52314033
142MP0001348_abnormal_lacrimal_gland0.51815198
143MP0003956_abnormal_body_size0.51358605
144MP0005379_endocrine/exocrine_gland_phen0.51347134

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.24449899
2Myokymia (HP:0002411)6.99622559
3Focal seizures (HP:0007359)5.64420323
4Visual hallucinations (HP:0002367)5.56924678
5Atonic seizures (HP:0010819)4.44072563
6Epileptic encephalopathy (HP:0200134)4.30924108
7Absence seizures (HP:0002121)4.14995297
8Febrile seizures (HP:0002373)4.10142351
9Progressive cerebellar ataxia (HP:0002073)4.08445849
10Supranuclear gaze palsy (HP:0000605)4.04575513
11Hyperacusis (HP:0010780)4.01567332
12Generalized tonic-clonic seizures (HP:0002069)3.81340788
13Dialeptic seizures (HP:0011146)3.71533427
14Ankle clonus (HP:0011448)3.66943901
15Action tremor (HP:0002345)3.61697153
16Depression (HP:0000716)3.43906349
17Ulnar bowing (HP:0003031)3.41482202
18Turricephaly (HP:0000262)3.33752530
19Broad-based gait (HP:0002136)3.30315796
20Abnormal eating behavior (HP:0100738)3.29987962
21Papilledema (HP:0001085)3.27621570
22Anxiety (HP:0000739)3.25576678
23Mutism (HP:0002300)3.24268148
24Poor eye contact (HP:0000817)3.21424726
25Impaired vibration sensation in the lower limbs (HP:0002166)3.15670205
26Achilles tendon contracture (HP:0001771)3.10435923
27Urinary bladder sphincter dysfunction (HP:0002839)3.02120838
28Shallow orbits (HP:0000586)2.98749693
29Postural instability (HP:0002172)2.96305868
30Dysmetria (HP:0001310)2.94863125
31Impaired social interactions (HP:0000735)2.93168880
32Abnormal social behavior (HP:0012433)2.93168880
33Overriding aorta (HP:0002623)2.92907579
34Truncal ataxia (HP:0002078)2.92010634
35Dysdiadochokinesis (HP:0002075)2.91496122
36Aplasia involving bones of the upper limbs (HP:0009823)2.91393793
37Amblyopia (HP:0000646)2.84520725
38Neurofibrillary tangles (HP:0002185)2.83080498
39Polyphagia (HP:0002591)2.83042398
40Distal upper limb amyotrophy (HP:0007149)2.82779342
41Upper limb amyotrophy (HP:0009129)2.82779342
42Genetic anticipation (HP:0003743)2.78485076
43Lower limb amyotrophy (HP:0007210)2.78448510
44Elfin facies (HP:0004428)2.76990495
45Premature rupture of membranes (HP:0001788)2.75339534
46Ventricular fibrillation (HP:0001663)2.74107653
47Gaze-evoked nystagmus (HP:0000640)2.73638724
48Cerebral inclusion bodies (HP:0100314)2.72457861
49Failure to thrive in infancy (HP:0001531)2.71721592
50Agitation (HP:0000713)2.70619168
51Bronchomalacia (HP:0002780)2.68955980
52Progressive inability to walk (HP:0002505)2.68535191
53Abnormality of the Achilles tendon (HP:0005109)2.64231428
54Hemiparesis (HP:0001269)2.63854739
55Urinary urgency (HP:0000012)2.59694554
56Spastic gait (HP:0002064)2.59084680
57Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.56824597
58Torticollis (HP:0000473)2.56765275
59Protrusio acetabuli (HP:0003179)2.56744835
60Renal duplication (HP:0000075)2.56720329
61Bradykinesia (HP:0002067)2.52346831
62Limb dystonia (HP:0002451)2.51845713
63Hemiplegia (HP:0002301)2.49432418
64Drooling (HP:0002307)2.48166517
65Excessive salivation (HP:0003781)2.48166517
66Abnormality of the lower motor neuron (HP:0002366)2.46631521
67Impaired smooth pursuit (HP:0007772)2.46531658
68Pheochromocytoma (HP:0002666)2.43681635
69Bladder diverticulum (HP:0000015)2.42786639
70Insomnia (HP:0100785)2.42472569
71Megalencephaly (HP:0001355)2.40142632
72Hyperventilation (HP:0002883)2.38859417
73Abnormality of the aortic arch (HP:0012303)2.37187359
74Focal dystonia (HP:0004373)2.35566787
75Diplopia (HP:0000651)2.33424697
76Abnormality of binocular vision (HP:0011514)2.33424697
77Intention tremor (HP:0002080)2.32390885
78Hypoventilation (HP:0002791)2.32016821
79Hand muscle atrophy (HP:0009130)2.31207578
80Epileptiform EEG discharges (HP:0011182)2.30243476
81EEG with generalized epileptiform discharges (HP:0011198)2.25782178
82Coronal craniosynostosis (HP:0004440)2.25575693
83Scanning speech (HP:0002168)2.24338747
84Difficulty climbing stairs (HP:0003551)2.22166665
85Arnold-Chiari malformation (HP:0002308)2.20151470
86Stereotypic behavior (HP:0000733)2.19754706
87Lower limb muscle weakness (HP:0007340)2.19477124
88Bowel diverticulosis (HP:0005222)2.17226946
89Hypsarrhythmia (HP:0002521)2.16172382
90Genu recurvatum (HP:0002816)2.16070188
91Status epilepticus (HP:0002133)2.15646175
92Bowed forearm bones (HP:0003956)2.14673585
93Bowing of the arm (HP:0006488)2.14673585
94Craniofacial dystonia (HP:0012179)2.14247954
95Termporal pattern (HP:0011008)2.14071779
96Insidious onset (HP:0003587)2.14071779
97Psychosis (HP:0000709)2.13817871
98Spinal rigidity (HP:0003306)2.13352386
99Neonatal short-limb short stature (HP:0008921)2.12486163
100Abnormality of the corticospinal tract (HP:0002492)2.12149566
101Sleep apnea (HP:0010535)2.11636094
102Abnormality of ocular smooth pursuit (HP:0000617)2.11121430
103Distal lower limb amyotrophy (HP:0008944)2.10637334
104Hypercortisolism (HP:0001578)2.10005397
105Renovascular hypertension (HP:0100817)2.09861337
106Neuroendocrine neoplasm (HP:0100634)2.08981219
107Congenital glaucoma (HP:0001087)2.06670809
108Abnormal EKG (HP:0003115)2.05244154
109Apathy (HP:0000741)2.03428003
110Abnormality of dentin (HP:0010299)2.02685423
111Neuronal loss in central nervous system (HP:0002529)2.02642254
112Generalized myoclonic seizures (HP:0002123)2.01990171
113Broad face (HP:0000283)1.99766585
114Obstructive sleep apnea (HP:0002870)1.99244200
115Delusions (HP:0000746)1.98638061
116Rapidly progressive (HP:0003678)1.98324793
117Absent speech (HP:0001344)1.98280905
118Fetal akinesia sequence (HP:0001989)1.97922490
119Pointed chin (HP:0000307)1.97865148
120Cerebral aneurysm (HP:0004944)1.97389294
121Mitral regurgitation (HP:0001653)1.95852557
122Impaired vibratory sensation (HP:0002495)1.94279377
123Inability to walk (HP:0002540)1.91567646
124Broad distal phalanx of finger (HP:0009836)1.90313003
125Precocious puberty (HP:0000826)1.90307628
126Deviation of the hallux (HP:0010051)1.89889616
127Partial duplication of the phalanx of hand (HP:0009999)1.88623530
128Clonus (HP:0002169)1.88257584
129Flat cornea (HP:0007720)1.86844312
130Rigidity (HP:0002063)1.86232613
131Hyperthyroidism (HP:0000836)1.86131133
132Long palpebral fissure (HP:0000637)1.86078008
133Hallux valgus (HP:0001822)1.86043078
134Anosmia (HP:0000458)1.84622739
135Menstrual irregularities (HP:0000858)1.84508695
136Stridor (HP:0010307)1.82696008
137Amyotrophic lateral sclerosis (HP:0007354)1.82445222
138Specific learning disability (HP:0001328)1.82071946
139Generalized hypotonia (HP:0001290)1.81207634
140Thin ribs (HP:0000883)1.80854921
141Annular pancreas (HP:0001734)1.80756486
142Diminished motivation (HP:0000745)1.79719142
143Nuclear cataract (HP:0100018)1.79546121
144Neoplasm of the heart (HP:0100544)1.78276608
145Gait ataxia (HP:0002066)1.77496021
146Disproportionate tall stature (HP:0001519)1.77144448
147Aplasia of the phalanges of the hand (HP:0009802)1.76632129
148Aplasia involving bones of the extremities (HP:0009825)1.76632129
149Truncus arteriosus (HP:0001660)1.75802087
150Patellar dislocation (HP:0002999)1.75276429
151Partial duplication of thumb phalanx (HP:0009944)1.74979943
152Ankle contracture (HP:0006466)1.74637526
153Hypercalcemia (HP:0003072)1.73157890
154Buphthalmos (HP:0000557)1.70605890
155Broad metatarsal (HP:0001783)1.69684875
156Hammertoe (HP:0001765)1.67904504
157Megalocornea (HP:0000485)1.67303813
158Split foot (HP:0001839)1.64692898
159Vertebral arch anomaly (HP:0008438)1.64301463
160Peripheral hypomyelination (HP:0007182)1.63200466
161Abnormality of the 4th metacarpal (HP:0010012)1.59211123
162Mildly elevated creatine phosphokinase (HP:0008180)1.57616011
163Abnormality of the phalanges of the hallux (HP:0010057)1.57002834
164Trigonocephaly (HP:0000243)1.56281458
165Fragile skin (HP:0001030)1.56018591
166Adducted thumb (HP:0001181)1.55746057

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK34.63042027
2MAP3K94.36593487
3EPHA43.95476487
4MARK13.07738679
5TRIB32.92496619
6MAP3K42.89069626
7MINK12.77543123
8ICK2.62778888
9NTRK22.43857566
10PAK62.40013801
11MAP3K122.28921760
12MAP2K72.25858039
13DAPK22.24068592
14NTRK12.22167071
15KSR22.21677470
16PRKD32.17784274
17EPHB22.17327983
18SIK12.12960415
19MAP2K41.90298057
20EEF2K1.75468501
21IRAK31.72694203
22CAMKK11.69933445
23PDGFRA1.68321897
24CDK51.60495996
25PNCK1.60367109
26ARAF1.60063496
27RIPK41.57019856
28TNIK1.56139383
29CDK121.55786801
30UHMK11.54429495
31GRK51.53295622
32CDK191.52262898
33SMG11.50432361
34KSR11.47334662
35DDR21.46507850
36TESK11.42252280
37PTK21.40386320
38MAP3K21.37714488
39SIK21.35233039
40CASK1.32802266
41STK381.30996153
42DAPK11.29621943
43FES1.29322942
44MAP3K101.23322941
45TYRO31.22454811
46PLK21.22425591
47MAPK131.22095998
48PRKCG1.17128545
49TAOK11.17100534
50LATS21.16912255
51TAOK21.13892448
52MAP3K131.12966733
53PHKG21.07448880
54PHKG11.07448880
55STK110.99595939
56MTOR0.97189633
57CAMK10.96904056
58PAK30.96876845
59CAMK2A0.96555978
60DYRK20.94610480
61TTN0.92741126
62CDK180.92649417
63CDK140.92235653
64CDK150.92043171
65EPHA20.91120334
66PRPF4B0.89650607
67ALK0.88203211
68CAMKK20.88003592
69RET0.87919262
70PRKCH0.86799496
71MAP3K10.84996711
72LIMK10.84400307
73PKN20.83842824
74CDK11A0.82974625
75LMTK20.82594880
76MAP3K110.82294469
77TNK20.80417983
78CAMK2B0.77279461
79MARK20.77079684
80CAMK1D0.76768032
81MOS0.76602521
82ABL20.75174168
83SGK4940.73170253
84SGK2230.73170253
85PAK20.73099210
86RAF10.69666677
87PIM20.67923293
88FGFR20.67112776
89DYRK1A0.64733689
90CSNK1G20.64427127
91FGFR40.64391940
92IRAK20.63995522
93DYRK1B0.61384447
94NME10.61365727
95HIPK20.60334467
96SGK10.59674089
97CDC42BPA0.59451202
98OXSR10.56620274
99WNK30.56479227
100FER0.56367282
101CAMK1G0.54940875
102PDPK10.54385155
103PINK10.53788429
104PDK10.51700214
105AKT20.51356780
106PTK2B0.51181303
107CAMK2G0.51166962
108PRKCZ0.50539197
109PKN10.50170699
110ROCK10.49976278
111BMX0.49606234
112MAP2K20.48964160
113CAMK2D0.48166657
114RPS6KA30.47697357
115MAPK100.46850500
116SCYL20.46644866
117SGK20.46392880
118RPS6KC10.45652558
119RPS6KL10.45652558
120MAPK150.45368331
121BMPR20.44662357
122PDGFRB0.44408705
123PRKCE0.44245787
124DAPK30.44053577
125RPS6KA20.43331007
126FYN0.42992174
127SGK30.42641202
128RIPK10.42212053
129BRD40.41886009
130BRSK10.40434225
131BRAF0.38020907
132CAMK40.37649582
133NEK60.37171833
134GRK70.36545011
135MAP3K70.36148629
136MAP2K10.33543720
137PRKD20.33433496
138WNK10.33309008
139ROCK20.32721390
140ADRBK10.31175457
141MAPKAPK50.30698764

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.65317390
2Synaptic vesicle cycle_Homo sapiens_hsa047213.43545593
3GABAergic synapse_Homo sapiens_hsa047272.80993574
4Olfactory transduction_Homo sapiens_hsa047402.71104690
5Circadian entrainment_Homo sapiens_hsa047132.59977748
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.54931507
7Long-term potentiation_Homo sapiens_hsa047202.51367802
8Glutamatergic synapse_Homo sapiens_hsa047242.48696269
9Morphine addiction_Homo sapiens_hsa050322.46029261
10Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.44396567
11Amphetamine addiction_Homo sapiens_hsa050312.43109143
12Dopaminergic synapse_Homo sapiens_hsa047282.17654313
13Insulin secretion_Homo sapiens_hsa049112.15230033
14Salivary secretion_Homo sapiens_hsa049702.08803298
15Cholinergic synapse_Homo sapiens_hsa047251.91640249
16Cocaine addiction_Homo sapiens_hsa050301.90586761
17Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.90455476
18Gastric acid secretion_Homo sapiens_hsa049711.89583062
19Taste transduction_Homo sapiens_hsa047421.81486151
20Aldosterone synthesis and secretion_Homo sapiens_hsa049251.81027541
21Serotonergic synapse_Homo sapiens_hsa047261.67361827
22Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.67181065
23Long-term depression_Homo sapiens_hsa047301.64314887
24Renin secretion_Homo sapiens_hsa049241.62935468
25Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.61626780
26Collecting duct acid secretion_Homo sapiens_hsa049661.57108881
27Oxytocin signaling pathway_Homo sapiens_hsa049211.56286510
28GnRH signaling pathway_Homo sapiens_hsa049121.50172103
29Vitamin B6 metabolism_Homo sapiens_hsa007501.49753134
30Notch signaling pathway_Homo sapiens_hsa043301.48537541
31Calcium signaling pathway_Homo sapiens_hsa040201.47789609
32Hippo signaling pathway_Homo sapiens_hsa043901.43465733
33Basal cell carcinoma_Homo sapiens_hsa052171.41504627
34Gap junction_Homo sapiens_hsa045401.36568972
35Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.31367987
36Type II diabetes mellitus_Homo sapiens_hsa049301.25475382
37Estrogen signaling pathway_Homo sapiens_hsa049151.23740519
38Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.23078236
39cAMP signaling pathway_Homo sapiens_hsa040241.22559204
40Hedgehog signaling pathway_Homo sapiens_hsa043401.22286948
41Vibrio cholerae infection_Homo sapiens_hsa051101.16722078
42Cardiac muscle contraction_Homo sapiens_hsa042601.15776186
43Melanogenesis_Homo sapiens_hsa049161.15747750
44ECM-receptor interaction_Homo sapiens_hsa045121.12564086
45Bladder cancer_Homo sapiens_hsa052191.12341560
46Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.11533113
47Axon guidance_Homo sapiens_hsa043601.09928255
48Glioma_Homo sapiens_hsa052141.09501172
49Central carbon metabolism in cancer_Homo sapiens_hsa052301.06817426
50Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.06013680
51Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.05212824
52Focal adhesion_Homo sapiens_hsa045101.05101957
53Phosphatidylinositol signaling system_Homo sapiens_hsa040701.03740611
54ErbB signaling pathway_Homo sapiens_hsa040121.00987182
55Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.96678186
56cGMP-PKG signaling pathway_Homo sapiens_hsa040220.92430800
57Dorso-ventral axis formation_Homo sapiens_hsa043200.89416818
58Vascular smooth muscle contraction_Homo sapiens_hsa042700.88885003
59Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.88025979
60Oocyte meiosis_Homo sapiens_hsa041140.86774659
61Chronic myeloid leukemia_Homo sapiens_hsa052200.85724177
62Phospholipase D signaling pathway_Homo sapiens_hsa040720.85696495
63Adherens junction_Homo sapiens_hsa045200.85150211
64Nitrogen metabolism_Homo sapiens_hsa009100.84334570
65Pancreatic secretion_Homo sapiens_hsa049720.83772541
66Proteoglycans in cancer_Homo sapiens_hsa052050.82726714
67Thyroid hormone synthesis_Homo sapiens_hsa049180.81036240
68MicroRNAs in cancer_Homo sapiens_hsa052060.80712564
69Type I diabetes mellitus_Homo sapiens_hsa049400.80033199
70Tight junction_Homo sapiens_hsa045300.79412615
71AMPK signaling pathway_Homo sapiens_hsa041520.78872994
72AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.78530442
73Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.77583645
74Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.74032329
75MAPK signaling pathway_Homo sapiens_hsa040100.73451434
76Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.72636076
77Phototransduction_Homo sapiens_hsa047440.71941481
78Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.71839369
79Dilated cardiomyopathy_Homo sapiens_hsa054140.71618379
80Glycosaminoglycan degradation_Homo sapiens_hsa005310.71389438
81Sulfur relay system_Homo sapiens_hsa041220.70262921
82Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.69137108
83Neurotrophin signaling pathway_Homo sapiens_hsa047220.68965222
84Carbohydrate digestion and absorption_Homo sapiens_hsa049730.67818429
85Choline metabolism in cancer_Homo sapiens_hsa052310.67436042
86Colorectal cancer_Homo sapiens_hsa052100.66108670
87Other glycan degradation_Homo sapiens_hsa005110.64465159
88Amoebiasis_Homo sapiens_hsa051460.62839471
89Salmonella infection_Homo sapiens_hsa051320.62777583
90VEGF signaling pathway_Homo sapiens_hsa043700.62440928
91Alcoholism_Homo sapiens_hsa050340.62390611
92Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.59693376
93Prion diseases_Homo sapiens_hsa050200.59231940
94Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.58283018
95Alzheimers disease_Homo sapiens_hsa050100.58188727
96Ras signaling pathway_Homo sapiens_hsa040140.56920946
97Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.55299376
98Sphingolipid signaling pathway_Homo sapiens_hsa040710.54358660
99Regulation of actin cytoskeleton_Homo sapiens_hsa048100.54343765
100Glucagon signaling pathway_Homo sapiens_hsa049220.54310322
101Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.54058942
102Thyroid hormone signaling pathway_Homo sapiens_hsa049190.52782248
103Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.52700515
104Pathways in cancer_Homo sapiens_hsa052000.51743983
105Endocytosis_Homo sapiens_hsa041440.51631918
106Lysosome_Homo sapiens_hsa041420.50624314
107Rap1 signaling pathway_Homo sapiens_hsa040150.49219211
108Oxidative phosphorylation_Homo sapiens_hsa001900.47867808
109Insulin signaling pathway_Homo sapiens_hsa049100.46638088
110Bile secretion_Homo sapiens_hsa049760.45657274
111Wnt signaling pathway_Homo sapiens_hsa043100.45080144
112mTOR signaling pathway_Homo sapiens_hsa041500.45005562
113Renal cell carcinoma_Homo sapiens_hsa052110.44854895
114Parkinsons disease_Homo sapiens_hsa050120.43845309
115Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.43278947
116Endometrial cancer_Homo sapiens_hsa052130.43115441
117Inositol phosphate metabolism_Homo sapiens_hsa005620.41857079
118Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.41666152
119Non-small cell lung cancer_Homo sapiens_hsa052230.39939497
120Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.39009120
121Longevity regulating pathway - mammal_Homo sapiens_hsa042110.36934194
122Ovarian steroidogenesis_Homo sapiens_hsa049130.36886157
123SNARE interactions in vesicular transport_Homo sapiens_hsa041300.34931512
124Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.34874682
125Circadian rhythm_Homo sapiens_hsa047100.32748518
126Chemokine signaling pathway_Homo sapiens_hsa040620.29690824
127Prolactin signaling pathway_Homo sapiens_hsa049170.28968246
128Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.28737966
129Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.27050671
130Huntingtons disease_Homo sapiens_hsa050160.26013560

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »