CBLB

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative thymic T cell selection (GO:0045060)5.19434324
2negative T cell selection (GO:0043383)5.06266279
3positive regulation of gamma-delta T cell activation (GO:0046645)5.02908958
4pyrimidine ribonucleoside catabolic process (GO:0046133)4.84446791
5cytidine deamination (GO:0009972)4.72373853
6cytidine metabolic process (GO:0046087)4.72373853
7cytidine catabolic process (GO:0006216)4.72373853
8regulation of interleukin-12 biosynthetic process (GO:0045075)4.64566930
9NIK/NF-kappaB signaling (GO:0038061)4.56898172
10negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.46056978
11negative regulation of cell killing (GO:0031342)4.46056978
12activated T cell proliferation (GO:0050798)4.38015064
13regulation of lymphocyte chemotaxis (GO:1901623)4.35961337
14positive thymic T cell selection (GO:0045059)4.18449194
15thymic T cell selection (GO:0045061)4.17347817
16regulation of gamma-delta T cell differentiation (GO:0045586)4.02523552
17regulation of T cell chemotaxis (GO:0010819)3.99251277
18positive regulation of T cell chemotaxis (GO:0010820)3.99251277
19T cell selection (GO:0045058)3.90486311
20antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.82106542
21antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.82106542
22regulation of gamma-delta T cell activation (GO:0046643)3.81300358
23positive regulation of calcium-mediated signaling (GO:0050850)3.80383825
24positive T cell selection (GO:0043368)3.64623868
25antigen processing and presentation of endogenous antigen (GO:0019883)3.60984730
26negative regulation by host of viral transcription (GO:0043922)3.56976478
27establishment of protein localization to Golgi (GO:0072600)3.46968834
28regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.46422737
29interferon-gamma production (GO:0032609)3.43629831
30neural tube formation (GO:0001841)3.39266225
31regulation of chemokine-mediated signaling pathway (GO:0070099)3.35268627
32positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.33651969
33growth hormone receptor signaling pathway (GO:0060396)3.33498842
34protein targeting to Golgi (GO:0000042)3.33131244
35response to interleukin-15 (GO:0070672)3.32623084
36phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.27428872
37antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.26536430
38positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.25897137
39positive regulation of natural killer cell mediated immunity (GO:0002717)3.25746372
40positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)3.25603250
41cytoplasmic mRNA processing body assembly (GO:0033962)3.25275311
42positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.20817774
43DNA deamination (GO:0045006)3.19122989
44dopaminergic neuron differentiation (GO:0071542)3.16149737
45JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)3.07711914
46eosinophil chemotaxis (GO:0048245)3.03897634
47regulation of regulatory T cell differentiation (GO:0045589)3.01644440
48retrograde transport, vesicle recycling within Golgi (GO:0000301)3.00220942
49regulation of B cell differentiation (GO:0045577)2.98948929
50myeloid dendritic cell differentiation (GO:0043011)2.98669187
51tolerance induction (GO:0002507)2.98269225
52cell proliferation involved in metanephros development (GO:0072203)2.95348019
53cellular response to interleukin-15 (GO:0071350)2.94509051
54positive regulation of granulocyte differentiation (GO:0030854)2.94498567
55T cell migration (GO:0072678)2.93819443
56regulation of B cell receptor signaling pathway (GO:0050855)2.91118358
57positive regulation of lymphocyte migration (GO:2000403)2.90201886
58antigen processing and presentation via MHC class Ib (GO:0002475)2.88518910
59regulation of calcium-mediated signaling (GO:0050848)2.87696474
60positive regulation of defense response to virus by host (GO:0002230)2.87251113
61CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.86464174
62pre-miRNA processing (GO:0031054)2.85122758
63cellular response to growth hormone stimulus (GO:0071378)2.84174789
64myeloid dendritic cell activation (GO:0001773)2.82959497
65regulation of chronic inflammatory response (GO:0002676)2.81981869
66radial glial cell differentiation (GO:0060019)2.81382364
67positive regulation of developmental pigmentation (GO:0048087)2.78242202
68positive regulation of interleukin-2 production (GO:0032743)2.77541422
69lateral sprouting from an epithelium (GO:0060601)2.73713325
70negative regulation of neurotransmitter secretion (GO:0046929)2.73106816
71negative regulation of translation, ncRNA-mediated (GO:0040033)2.73035513
72regulation of translation, ncRNA-mediated (GO:0045974)2.73035513
73negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.73035513
74T cell costimulation (GO:0031295)2.72842687
75T-helper cell differentiation (GO:0042093)2.72830179
76CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.72830179
77peripheral nervous system neuron development (GO:0048935)2.68876509
78eosinophil migration (GO:0072677)2.66961107
79* NLS-bearing protein import into nucleus (GO:0006607)2.66603725
80positive regulation of humoral immune response (GO:0002922)2.66557501
81lymphocyte costimulation (GO:0031294)2.66474253
82* regulation of T cell receptor signaling pathway (GO:0050856)2.66013656
83positive regulation of isotype switching (GO:0045830)2.63126646
84tyrosine phosphorylation of STAT protein (GO:0007260)2.62459145
85T cell receptor signaling pathway (GO:0050852)2.62300575
86regulation of mononuclear cell migration (GO:0071675)2.61593238
87positive regulation of leukocyte mediated cytotoxicity (GO:0001912)2.59379321
88positive regulation of histone deacetylation (GO:0031065)2.59155679
89regulation of isotype switching to IgG isotypes (GO:0048302)2.58117574
90histone H3-K4 trimethylation (GO:0080182)2.57935122
91positive regulation of cell killing (GO:0031343)2.57425196
92regulation of leukocyte mediated cytotoxicity (GO:0001910)2.56450430
93leukocyte aggregation (GO:0070486)2.56108982
94metanephric mesenchyme development (GO:0072075)2.55349626
95regulation of cell killing (GO:0031341)2.54857921
96negative regulation of B cell activation (GO:0050869)2.54670680
97T cell differentiation (GO:0030217)2.54277614
98positive regulation of natural killer cell differentiation (GO:0032825)2.53901601
99positive regulation of B cell differentiation (GO:0045579)2.53661744
100B cell homeostasis (GO:0001782)2.53124582
101negative regulation of B cell proliferation (GO:0030889)2.53066523
102positive regulation of alpha-beta T cell proliferation (GO:0046641)2.53034874
103* regulation of alpha-beta T cell proliferation (GO:0046640)2.52902371
104mitotic sister chromatid cohesion (GO:0007064)2.49430607
105positive regulation of lymphocyte apoptotic process (GO:0070230)2.47421425
106mesenchymal-epithelial cell signaling (GO:0060638)2.47273502
107fibroblast migration (GO:0010761)2.47157016
108* regulation of T cell tolerance induction (GO:0002664)2.46953716
109regulation of pigment cell differentiation (GO:0050932)2.46864147
110antigen receptor-mediated signaling pathway (GO:0050851)2.46423006
111epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.46175994
112histone H3-K36 demethylation (GO:0070544)2.42865740
113negative regulation of T cell mediated immunity (GO:0002710)2.42270261
114T cell differentiation involved in immune response (GO:0002292)2.41842057
115alpha-beta T cell differentiation involved in immune response (GO:0002293)2.41842057
116alpha-beta T cell activation involved in immune response (GO:0002287)2.41842057
117alpha-beta T cell activation (GO:0046631)2.41466713
118limb development (GO:0060173)2.41446279
119appendage development (GO:0048736)2.41446279
120positive regulation of leukocyte apoptotic process (GO:2000108)2.41176701
121monocyte chemotaxis (GO:0002548)2.40963292
122B cell receptor signaling pathway (GO:0050853)2.40309679
123negative regulation of T-helper cell differentiation (GO:0045623)2.39535261
124negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.39535261
125cell proliferation involved in kidney development (GO:0072111)2.39312902
126regulation of thymocyte apoptotic process (GO:0070243)2.38234563
127regulation of type I interferon-mediated signaling pathway (GO:0060338)2.38229490
128behavioral response to nicotine (GO:0035095)2.38060492
129regulation of interleukin-2 biosynthetic process (GO:0045076)2.37665925
130histone H3-K4 methylation (GO:0051568)2.36359968
131germinal center formation (GO:0002467)2.35498824
132T cell proliferation (GO:0042098)2.35261728
133CD4-positive, alpha-beta T cell differentiation (GO:0043367)2.34543431
134regulation of lymphocyte migration (GO:2000401)2.34332838
135response to muramyl dipeptide (GO:0032495)2.32088543
136response to prostaglandin E (GO:0034695)2.31757265
137T cell homeostasis (GO:0043029)2.31684544
138embryonic hemopoiesis (GO:0035162)2.30775863
139nuclear pore complex assembly (GO:0051292)2.29368557
140heterotypic cell-cell adhesion (GO:0034113)2.27775157
141alpha-beta T cell differentiation (GO:0046632)2.26620612
142* regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.26583457
143positive regulation of extrinsic apoptotic signaling pathway via death domain receptors (GO:1902043)2.25059419
144positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.25027694
145neutrophil activation (GO:0042119)2.24902445
146regulation of natural killer cell mediated immunity (GO:0002715)2.24336325
147regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.24336325
148B cell proliferation (GO:0042100)2.24138421
149positive regulation of B cell proliferation (GO:0030890)2.24034378
150lymphocyte homeostasis (GO:0002260)2.23236608
151regulation of NFAT protein import into nucleus (GO:0051532)2.21875788
152regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.21874569
153positive regulation of T cell cytokine production (GO:0002726)2.21871867
154natural killer cell mediated cytotoxicity (GO:0042267)2.21565085
155natural killer cell mediated immunity (GO:0002228)2.21565085
156natural killer cell differentiation (GO:0001779)2.21132620
157negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.20819776
158positive regulation of T cell apoptotic process (GO:0070234)2.20777571

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse7.00316495
2STAT6_20620947_ChIP-Seq_CD4_POS_T_Human5.11461062
3EGR1_19374776_ChIP-ChIP_THP-1_Human4.73609386
4* NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse4.23711002
5IRF8_22096565_ChIP-ChIP_GC-B_Human3.76052890
6* STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.24825098
7MYC_22102868_ChIP-Seq_BL_Human3.01525097
8IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.95805435
9RUNX_20019798_ChIP-Seq_JUKART_Human2.94041688
10* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.70859515
11VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.70376839
12HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.64520922
13BP1_19119308_ChIP-ChIP_Hs578T_Human2.59160862
14TP63_19390658_ChIP-ChIP_HaCaT_Human2.57314293
15IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.45124944
16SMAD_19615063_ChIP-ChIP_OVARY_Human2.31225199
17TCF7_22412390_ChIP-Seq_EML_Mouse2.30850186
18MAF_26560356_Chip-Seq_TH1_Human2.30109296
19FLI1_27457419_Chip-Seq_LIVER_Mouse2.29435541
20STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.26910897
21KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.25238594
22* MYB_26560356_Chip-Seq_TH2_Human2.22494591
23VDR_21846776_ChIP-Seq_THP-1_Human2.21430324
24PCGF2_27294783_Chip-Seq_NPCs_Mouse2.17881432
25SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.17517764
26* ZFP57_27257070_Chip-Seq_ESCs_Mouse2.13437783
27KDM2B_26808549_Chip-Seq_DND41_Human2.12558908
28IRF8_21731497_ChIP-ChIP_J774_Mouse2.11912788
29* STAT4_19710469_ChIP-ChIP_TH1__Mouse2.11431796
30MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.09157335
31NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.08278496
32MYB_26560356_Chip-Seq_TH1_Human2.05349394
33GBX2_23144817_ChIP-Seq_PC3_Human2.04478750
34RBPJ_22232070_ChIP-Seq_NCS_Mouse2.01711234
35IRF8_27001747_Chip-Seq_BMDM_Mouse2.00254568
36KDM2B_26808549_Chip-Seq_SUP-B15_Human1.99995253
37PCGF2_27294783_Chip-Seq_ESCs_Mouse1.99401876
38* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.98336713
39* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.98036201
40EZH2_22144423_ChIP-Seq_EOC_Human1.97777279
41VDR_22108803_ChIP-Seq_LS180_Human1.93280018
42E2F7_22180533_ChIP-Seq_HELA_Human1.91650275
43KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.89116621
44UTX_26944678_Chip-Seq_JUKART_Human1.88120906
45SUZ12_27294783_Chip-Seq_NPCs_Mouse1.84381584
46RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.83803254
47* VDR_24763502_ChIP-Seq_THP-1_Human1.78180153
48NFE2_27457419_Chip-Seq_LIVER_Mouse1.63458725
49MYB_21317192_ChIP-Seq_ERMYB_Mouse1.63145546
50FUS_26573619_Chip-Seq_HEK293_Human1.59717469
51CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.59552562
52EZH2_27294783_Chip-Seq_NPCs_Mouse1.59127031
53KDM2B_26808549_Chip-Seq_JURKAT_Human1.58862705
54ZNF274_21170338_ChIP-Seq_K562_Hela1.58557565
55CTBP2_25329375_ChIP-Seq_LNCAP_Human1.58136928
56ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.57488149
57SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.57444946
58VDR_24787735_ChIP-Seq_THP-1_Human1.56582485
59SPI1_23127762_ChIP-Seq_K562_Human1.55894714
60GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.54126668
61* P300_19829295_ChIP-Seq_ESCs_Human1.53499879
62* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.50967501
63TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.48914199
64ELK3_25401928_ChIP-Seq_HUVEC_Human1.48164771
65EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.47961585
66* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.46729325
67GATA3_27048872_Chip-Seq_THYMUS_Human1.44242823
68CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.42116950
69DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.41973641
70SCL_19346495_ChIP-Seq_HPC-7_Human1.40150823
71TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.37312523
72ER_23166858_ChIP-Seq_MCF-7_Human1.37099161
73PIAS1_25552417_ChIP-Seq_VCAP_Human1.36876872
74BRD4_27068464_Chip-Seq_AML-cells_Mouse1.36260673
75IGF1R_20145208_ChIP-Seq_DFB_Human1.36121467
76* BCAT_22108803_ChIP-Seq_LS180_Human1.35637446
77SMAD4_21799915_ChIP-Seq_A2780_Human1.35394617
78TAF15_26573619_Chip-Seq_HEK293_Human1.32946200
79TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.32676972
80POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.32676972
81SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.31681333
82FOXM1_23109430_ChIP-Seq_U2OS_Human1.31043461
83BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.30950558
84NANOG_18555785_Chip-Seq_ESCs_Mouse1.30384113
85CIITA_25753668_ChIP-Seq_RAJI_Human1.29838700
86* CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.28840523
87CRX_20693478_ChIP-Seq_RETINA_Mouse1.28341341
88* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.28275422
89WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.28147282
90UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.28042656
91NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.27639445
92MAF_26560356_Chip-Seq_TH2_Human1.27585090
93TP63_17297297_ChIP-ChIP_HaCaT_Human1.27582702
94* SMAD3_21741376_ChIP-Seq_EPCs_Human1.25867464
95ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.25731368
96MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.25251367
97CBX2_27304074_Chip-Seq_ESCs_Mouse1.25194329
98PRDM14_20953172_ChIP-Seq_ESCs_Human1.25060222
99SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.24586601
100RUNX1_22412390_ChIP-Seq_EML_Mouse1.24404733
101* STAT3_23295773_ChIP-Seq_U87_Human1.24097005
102EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.23734843
103CTBP1_25329375_ChIP-Seq_LNCAP_Human1.23595089
104Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.21806759
105NOTCH1_21737748_ChIP-Seq_TLL_Human1.21093394
106PU_27001747_Chip-Seq_BMDM_Mouse1.20607189
107OCT4_21477851_ChIP-Seq_ESCs_Mouse1.20549792
108ZFP281_27345836_Chip-Seq_ESCs_Mouse1.19521009
109BMI1_23680149_ChIP-Seq_NPCS_Mouse1.18162915
110CDX2_19796622_ChIP-Seq_MESCs_Mouse1.17831512
111SALL1_21062744_ChIP-ChIP_HESCs_Human1.17803534
112FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.17080474
113E2F1_18555785_Chip-Seq_ESCs_Mouse1.16715072
114GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.15890131
115ARNT_22903824_ChIP-Seq_MCF-7_Human1.15552416
116* AR_25329375_ChIP-Seq_VCAP_Human1.15338772
117NR3C1_21868756_ChIP-Seq_MCF10A_Human1.15309362
118* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.14823139
119* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.12241884
120P53_22387025_ChIP-Seq_ESCs_Mouse1.12184001
121KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.11685730
122* IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.08570299
123* CBP_20019798_ChIP-Seq_JUKART_Human1.08570299
124TCF4_18268006_ChIP-ChIP_LS174T_Human1.08354624
125RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.08125060
126RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.07031800
127STAT6_21828071_ChIP-Seq_BEAS2B_Human1.06788559
128BRD4_25478319_ChIP-Seq_HGPS_Human1.06382261
129TCF4_23295773_ChIP-Seq_U87_Human1.06215028
130SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.04960240
131TP53_16413492_ChIP-PET_HCT116_Human1.04555449
132SPI1_23547873_ChIP-Seq_NB4_Human1.04493693
133NFIB_24661679_ChIP-Seq_LUNG_Mouse1.03670256
134OCT4_18555785_Chip-Seq_ESCs_Mouse1.03490243
135P300_27058665_Chip-Seq_ZR-75-30cells_Human1.03230578
136TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.03010439
137CMYC_18555785_Chip-Seq_ESCs_Mouse1.01711510
138SUZ12_18555785_Chip-Seq_ESCs_Mouse1.01364440
139* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.00043069
140CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.99928627
141FLI1_21867929_ChIP-Seq_TH2_Mouse0.99694838
142PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.98467581
143P300_18555785_Chip-Seq_ESCs_Mouse0.97605284
144TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.97540800
145* TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.96552638
146THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.96197883
147EZH2_27304074_Chip-Seq_ESCs_Mouse0.95884999
148* RUNX2_22187159_ChIP-Seq_PCA_Human0.95250553
149MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.95133681
150TP53_18474530_ChIP-ChIP_U2OS_Human0.94735106
151EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.94671789
152* FOXO3_23340844_ChIP-Seq_DLD1_Human0.91114888
153KDM2B_26808549_Chip-Seq_K562_Human0.90236826
154PKCTHETA_26484144_Chip-Seq_BREAST_Human0.87662994
155WT1_19549856_ChIP-ChIP_CCG9911_Human0.86648614
156HIF1A_21447827_ChIP-Seq_MCF-7_Human0.86115056
157PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.85583280
158UBF1/2_26484160_Chip-Seq_HMECs_Human0.85241792
159* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.83551545
160TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.81935502
161KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.81630530
162SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.81371641
163SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.81371641
164* ZNF217_24962896_ChIP-Seq_MCF-7_Human0.81168396
165NCOR1_26117541_ChIP-Seq_K562_Human0.80799733
166CTNNB1_20460455_ChIP-Seq_HCT116_Human0.78405776
167ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.78284887
168AHR_22903824_ChIP-Seq_MCF-7_Human0.77079083
169DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.76988905
170GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.74714887
171FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.74714316
172SOX9_24532713_ChIP-Seq_HFSC_Mouse0.74219938

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation4.53286749
2MP0003011_delayed_dark_adaptation3.13655850
3MP0002166_altered_tumor_susceptibility2.99108242
4MP0003763_abnormal_thymus_physiology2.71700667
5MP0001835_abnormal_antigen_presentation2.68680751
6MP0000685_abnormal_immune_system2.58761366
7MP0005387_immune_system_phenotype2.46329897
8MP0001790_abnormal_immune_system2.46329897
9MP0000372_irregular_coat_pigmentation2.42477708
10MP0003300_gastrointestinal_ulcer2.34592882
11MP0002006_tumorigenesis2.31215660
12MP0004510_myositis2.30623960
13MP0001800_abnormal_humoral_immune2.27432421
14MP0005671_abnormal_response_to2.26172997
15MP0002638_abnormal_pupillary_reflex2.08768602
16MP0003436_decreased_susceptibility_to2.03167242
17MP0003303_peritoneal_inflammation2.02855210
18MP0002396_abnormal_hematopoietic_system1.95821134
19MP0003950_abnormal_plasma_membrane1.95075089
20MP0005076_abnormal_cell_differentiation1.93305681
21MP0002138_abnormal_hepatobiliary_system1.92729463
22MP0003045_fibrosis1.87718316
23MP0002009_preneoplasia1.86232232
24MP0002452_abnormal_antigen_presenting1.86131776
25MP0004381_abnormal_hair_follicle1.83477164
26MP0004808_abnormal_hematopoietic_stem1.82758209
27* MP0002398_abnormal_bone_marrow1.79645036
28* MP0005000_abnormal_immune_tolerance1.79387751
29MP0000703_abnormal_thymus_morphology1.78332039
30MP0002277_abnormal_respiratory_mucosa1.73870452
31* MP0002723_abnormal_immune_serum1.73681021
32* MP0002420_abnormal_adaptive_immunity1.72698170
33* MP0001819_abnormal_immune_cell1.72249287
34MP0002405_respiratory_system_inflammati1.68053269
35MP0005503_abnormal_tendon_morphology1.64270628
36MP0001873_stomach_inflammation1.62082656
37MP0005275_abnormal_skin_tensile1.61714615
38MP0002822_catalepsy1.60783997
39MP0003091_abnormal_cell_migration1.57757670
40MP0000733_abnormal_muscle_development1.55808384
41MP0001346_abnormal_lacrimal_gland1.55373948
42MP0000566_synostosis1.55036316
43* MP0000716_abnormal_immune_system1.54670305
44MP0004947_skin_inflammation1.53493675
45MP0005253_abnormal_eye_physiology1.51598543
46MP0010352_gastrointestinal_tract_polyps1.51118636
47MP0009278_abnormal_bone_marrow1.41123982
48MP0003880_abnormal_central_pattern1.39316205
49MP0006072_abnormal_retinal_apoptosis1.37039987
50MP0002722_abnormal_immune_system1.34088950
51MP0001984_abnormal_olfaction1.30946156
52MP0001502_abnormal_circadian_rhythm1.29914862
53MP0008961_abnormal_basal_metabolism1.29898259
54MP0000689_abnormal_spleen_morphology1.29845101
55MP0005187_abnormal_penis_morphology1.27998619
56MP0002254_reproductive_system_inflammat1.27049406
57MP0010307_abnormal_tumor_latency1.25538462
58MP0003183_abnormal_peptide_metabolism1.24616231
59MP0002933_joint_inflammation1.24517100
60MP0001299_abnormal_eye_distance/1.23695680
61MP0002938_white_spotting1.23487479
62MP0001348_abnormal_lacrimal_gland1.20562550
63MP0010386_abnormal_urinary_bladder1.20519173
64MP0003705_abnormal_hypodermis_morpholog1.20231055
65* MP0002429_abnormal_blood_cell1.20065109
66MP0005025_abnormal_response_to1.20031528
67MP0005645_abnormal_hypothalamus_physiol1.19282270
68MP0000778_abnormal_nervous_system1.18404376
69MP0002168_other_aberrant_phenotype1.17963870
70MP0000427_abnormal_hair_cycle1.17378427
71MP0003866_abnormal_defecation1.16087680
72MP0009333_abnormal_splenocyte_physiolog1.15608550
73MP0002998_abnormal_bone_remodeling1.14121760
74MP0002928_abnormal_bile_duct1.13603120
75MP0005075_abnormal_melanosome_morpholog1.13336738
76MP0002102_abnormal_ear_morphology1.12555764
77MP0004742_abnormal_vestibular_system1.11930173
78MP0004145_abnormal_muscle_electrophysio1.11898046
79MP0008789_abnormal_olfactory_epithelium1.10892364
80MP0005174_abnormal_tail_pigmentation1.10618969
81MP0002163_abnormal_gland_morphology1.09672187
82MP0001853_heart_inflammation1.08903527
83MP0000538_abnormal_urinary_bladder1.08542186
84MP0002837_dystrophic_cardiac_calcinosis1.08161418
85MP0010155_abnormal_intestine_physiology1.07668860
86MP0003448_altered_tumor_morphology1.07539137
87MP0002419_abnormal_innate_immunity1.07513238
88MP0000371_diluted_coat_color1.07475540
89MP0008995_early_reproductive_senescence1.04344624
90MP0002148_abnormal_hypersensitivity_rea1.03022963
91MP0000428_abnormal_craniofacial_morphol1.01791083
92MP0002653_abnormal_ependyma_morphology1.01779236
93MP0002751_abnormal_autonomic_nervous1.01242713
94MP0001501_abnormal_sleep_pattern1.01200234
95MP0005257_abnormal_intraocular_pressure1.01003591
96MP0010030_abnormal_orbit_morphology1.00167056
97MP0006276_abnormal_autonomic_nervous0.99567193
98MP0009785_altered_susceptibility_to0.95998346
99MP0008057_abnormal_DNA_replication0.95676807
100MP0001188_hyperpigmentation0.95625410
101MP0003172_abnormal_lysosome_physiology0.94525228
102MP0001293_anophthalmia0.92259074
103MP0000767_abnormal_smooth_muscle0.91193713
104MP0006082_CNS_inflammation0.89753394
105MP0001545_abnormal_hematopoietic_system0.89744004
106MP0005397_hematopoietic_system_phenotyp0.89744004
107MP0003567_abnormal_fetal_cardiomyocyte0.89375456
108MP0008438_abnormal_cutaneous_collagen0.89370642
109MP0006054_spinal_hemorrhage0.89022932
110MP0005408_hypopigmentation0.88694695
111MP0001533_abnormal_skeleton_physiology0.87348392
112MP0004134_abnormal_chest_morphology0.86110144
113MP0005390_skeleton_phenotype0.86101911
114MP0001119_abnormal_female_reproductive0.85273299
115MP0002925_abnormal_cardiovascular_devel0.84494273
116MP0000383_abnormal_hair_follicle0.84206725
117MP0005248_abnormal_Harderian_gland0.83719922
118MP0009250_abnormal_appendicular_skeleto0.83679595
119MP0001243_abnormal_dermal_layer0.82935820
120MP0005508_abnormal_skeleton_morphology0.82555904
121MP0001879_abnormal_lymphatic_vessel0.82459102
122MP0005310_abnormal_salivary_gland0.81744808
123MP0003566_abnormal_cell_adhesion0.81182125
124MP0005551_abnormal_eye_electrophysiolog0.80295666
125MP0000858_altered_metastatic_potential0.79828904
126MP0003279_aneurysm0.78799234
127MP0009764_decreased_sensitivity_to0.76108812
128MP0001845_abnormal_inflammatory_respons0.76058361
129MP0001958_emphysema0.75826151
130MP0003943_abnormal_hepatobiliary_system0.75524094
131MP0002932_abnormal_joint_morphology0.75491007
132MP0003942_abnormal_urinary_system0.75425268
133MP0000627_abnormal_mammary_gland0.75303908
134MP0000465_gastrointestinal_hemorrhage0.75160313
135MP0002282_abnormal_trachea_morphology0.74494585
136MP0000490_abnormal_crypts_of0.73721061
137MP0002109_abnormal_limb_morphology0.73073602
138MP0003453_abnormal_keratinocyte_physiol0.72407799
139MP0000537_abnormal_urethra_morphology0.71598939
140MP0010368_abnormal_lymphatic_system0.71545019
141MP0005023_abnormal_wound_healing0.70781416
142MP0001849_ear_inflammation0.70160937
143MP0002088_abnormal_embryonic_growth/wei0.69998585
144MP0004215_abnormal_myocardial_fiber0.68316404
145MP0000647_abnormal_sebaceous_gland0.67800442
146MP0005670_abnormal_white_adipose0.67114739
147MP0005379_endocrine/exocrine_gland_phen0.66358062
148MP0004084_abnormal_cardiac_muscle0.64693097
149MP0003724_increased_susceptibility_to0.64491206

Predicted human phenotypes

RankGene SetZ-score
1Short 4th metacarpal (HP:0010044)4.43893486
2Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)4.43893486
3Trigonocephaly (HP:0000243)3.92840149
4Abnormality of the fingertips (HP:0001211)3.88944180
5Abnormality of eosinophils (HP:0001879)3.56309056
6Abnormality of the parietal bone (HP:0002696)3.46393571
7Chronic diarrhea (HP:0002028)3.41593654
8Autoimmune hemolytic anemia (HP:0001890)3.34092314
9Midline defect of the nose (HP:0004122)3.27768210
10Thyroiditis (HP:0100646)3.25715275
11IgG deficiency (HP:0004315)3.21805278
12Abnormality of the renal cortex (HP:0011035)3.02870817
13Abnormality of the 4th metacarpal (HP:0010012)3.01652328
14Narrow palate (HP:0000189)2.86644950
15Pancreatic cysts (HP:0001737)2.78370522
16Increased density of long bones (HP:0006392)2.71590247
17Hyperventilation (HP:0002883)2.68375781
18Widely spaced teeth (HP:0000687)2.66266814
19T lymphocytopenia (HP:0005403)2.63538003
20Abnormality of T cell number (HP:0011839)2.61947969
21Chronic otitis media (HP:0000389)2.57700392
22Renal cortical cysts (HP:0000803)2.55326825
23Abnormality of the nasal septum (HP:0000419)2.54721732
24Increased IgM level (HP:0003496)2.54180342
25Recurrent viral infections (HP:0004429)2.53847619
26Recurrent fungal infections (HP:0002841)2.52453507
27Neoplasm of the heart (HP:0100544)2.47924426
28Shallow orbits (HP:0000586)2.47062922
29Neoplasm of the tracheobronchial system (HP:0100552)2.45692104
30Alveolar cell carcinoma (HP:0006519)2.42568304
31Broad metatarsal (HP:0001783)2.41666537
32Hemoptysis (HP:0002105)2.41509115
33Lymphopenia (HP:0001888)2.38389022
34Abnormality of the renal medulla (HP:0100957)2.38183541
35Long eyelashes (HP:0000527)2.35567621
36Gastrointestinal infarctions (HP:0005244)2.35329966
37Depressed nasal tip (HP:0000437)2.34942460
38Sparse lateral eyebrow (HP:0005338)2.34174294
39Anteriorly placed anus (HP:0001545)2.32118892
40Abnormality of incisor morphology (HP:0011063)2.31907280
41Broad face (HP:0000283)2.30232790
42Exostoses (HP:0100777)2.29952158
43Spinal cord lesions (HP:0100561)2.29423798
44Syringomyelia (HP:0003396)2.29423798
45Elevated erythrocyte sedimentation rate (HP:0003565)2.29014354
46Amyotrophic lateral sclerosis (HP:0007354)2.27910478
47Large earlobe (HP:0009748)2.27681646
48Abnormality of cells of the lymphoid lineage (HP:0012140)2.24592302
49Nephronophthisis (HP:0000090)2.23172713
50Joint swelling (HP:0001386)2.22163547
51Abnormality of the distal phalanx of the thumb (HP:0009617)2.21453984
52Supernumerary ribs (HP:0005815)2.20238466
53Aortic aneurysm (HP:0004942)2.15257701
54Encephalitis (HP:0002383)2.14493583
55Deep philtrum (HP:0002002)2.13627129
56Eczematoid dermatitis (HP:0000976)2.13621573
57Macroorchidism (HP:0000053)2.10151719
58Hypoproteinemia (HP:0003075)2.08919785
59Increased corneal curvature (HP:0100692)2.08451723
60Keratoconus (HP:0000563)2.08451723
61Combined immunodeficiency (HP:0005387)2.07498796
62Peritonitis (HP:0002586)2.06465975
63Limited elbow extension (HP:0001377)2.06259531
64Abnormality of the prostate (HP:0008775)2.05762066
65Molar tooth sign on MRI (HP:0002419)2.04717421
66Abnormality of midbrain morphology (HP:0002418)2.04717421
67Cerebral aneurysm (HP:0004944)2.03440608
68Adactyly (HP:0009776)2.03029643
69Tubular atrophy (HP:0000092)2.02617033
70Abnormality of the peritoneum (HP:0002585)2.02019052
71Chronic hepatic failure (HP:0100626)2.00297948
72Recurrent bronchitis (HP:0002837)1.99937117
73Aplasia cutis congenita (HP:0001057)1.99601669
74Mediastinal lymphadenopathy (HP:0100721)1.99456155
75Hematochezia (HP:0002573)1.99023815
76Volvulus (HP:0002580)1.98797036
77Myositis (HP:0100614)1.98420344
78Congenital stationary night blindness (HP:0007642)1.94643343
79Stomach cancer (HP:0012126)1.94615490
80Persistence of primary teeth (HP:0006335)1.94429991
81Bronchitis (HP:0012387)1.93413224
82Arterial thrombosis (HP:0004420)1.93392876
83Intestinal atresia (HP:0011100)1.93161491
84Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658)1.92929176
85Nasal polyposis (HP:0100582)1.92627402
86Hypoplastic labia majora (HP:0000059)1.92241667
87Autoimmune thrombocytopenia (HP:0001973)1.91624796
88Meningitis (HP:0001287)1.91307202
89Panhypogammaglobulinemia (HP:0003139)1.89965872
90Periodontitis (HP:0000704)1.89883113
91Abnormality of T cell physiology (HP:0011840)1.89240193
92Abnormality of the radial head (HP:0003995)1.88964686
93Stomatitis (HP:0010280)1.88770154
94Supernumerary bones of the axial skeleton (HP:0009144)1.88603182
95Absent frontal sinuses (HP:0002688)1.87742734
96Skin tags (HP:0010609)1.87619498
97Keratoconjunctivitis (HP:0001096)1.87590952
98Optic neuritis (HP:0100653)1.87443201
99Retrobulbar optic neuritis (HP:0100654)1.87443201
100Broad hallux (HP:0010055)1.87273478
101Abnormality of the pleura (HP:0002103)1.86708929
102Lip pit (HP:0100267)1.85446254
103Tubulointerstitial abnormality (HP:0001969)1.85344338
104Intestinal fistula (HP:0100819)1.85141016
105Medial flaring of the eyebrow (HP:0010747)1.84162018
106Short phalanx of the thumb (HP:0009660)1.83310491
107Hip dysplasia (HP:0001385)1.83097889
108Granulocytopenia (HP:0001913)1.82636453
109Abnormal delayed hypersensitivity skin test (HP:0002963)1.82509824
110Pancreatic fibrosis (HP:0100732)1.82441696
111Vasculitis (HP:0002633)1.81174465
112Down-sloping shoulders (HP:0200021)1.80706917
113Hyperacusis (HP:0010780)1.80484796
114Broad toe (HP:0001837)1.80389392
115IgA deficiency (HP:0002720)1.79909232
116Abnormal hair whorl (HP:0010721)1.79435378
117Genetic anticipation (HP:0003743)1.78615821
118Hemiplegia (HP:0002301)1.78279039
119Abnormality of the intervertebral disk (HP:0005108)1.77707771
120Chest pain (HP:0100749)1.76873419
121Spondylolisthesis (HP:0003302)1.76856955
122True hermaphroditism (HP:0010459)1.76711160
123Orchitis (HP:0100796)1.75745456
124Long palpebral fissure (HP:0000637)1.74896613
125Gaze-evoked nystagmus (HP:0000640)1.74650422
126Keratoconjunctivitis sicca (HP:0001097)1.74423337
127Basal cell carcinoma (HP:0002671)1.74393582
128Toxemia of pregnancy (HP:0100603)1.74192326
129Dilatation of the ascending aorta (HP:0005111)1.73934350
130Anal stenosis (HP:0002025)1.73202799
131Abnormality of T cells (HP:0002843)1.72294551
132Eosinophilia (HP:0001880)1.72293749
133Hypoplasia of the thymus (HP:0000778)1.72084974
134Tubulointerstitial fibrosis (HP:0005576)1.71929867
135Increased number of teeth (HP:0011069)1.71641714
136Dislocated radial head (HP:0003083)1.71434668
137Acute myeloid leukemia (HP:0004808)1.71280692
138Progressive cerebellar ataxia (HP:0002073)1.71169839
139Agammaglobulinemia (HP:0004432)1.70878000
140Pulmonary infiltrates (HP:0002113)1.70816150
141Abnormality of the labia majora (HP:0012881)1.70582737
142Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.69319377
143Severe combined immunodeficiency (HP:0004430)1.69024587
144Acute lymphatic leukemia (HP:0006721)1.68786340
145Follicular hyperkeratosis (HP:0007502)1.68388076
146Abnormality of the diencephalon (HP:0010662)1.67555321
147Milia (HP:0001056)1.66429474
148IgM deficiency (HP:0002850)1.66201482
149Absent speech (HP:0001344)1.66131532
150Leukocytosis (HP:0001974)1.66081932
151Arthropathy (HP:0003040)1.65107757
152Abnormality of dental color (HP:0011073)1.64617920
153Hypoplastic ischia (HP:0003175)1.64555699
154Aqueductal stenosis (HP:0002410)1.63991272
155Recurrent cutaneous fungal infections (HP:0011370)1.63006512
156Chronic mucocutaneous candidiasis (HP:0002728)1.63006512
157Broad thumb (HP:0011304)1.62752409
158Smooth philtrum (HP:0000319)1.61712516
159Aortic dissection (HP:0002647)1.61261140
160Bulbous nose (HP:0000414)1.60792124
161Mesomelia (HP:0003027)1.60784179
162Overgrowth (HP:0001548)1.60597542
163Deviation of the hallux (HP:0010051)1.60099889
164Albinism (HP:0001022)1.59959105
165Abnormality of the incisor (HP:0000676)1.59236668
166Spontaneous hematomas (HP:0007420)1.59102367
167Bronchiectasis (HP:0002110)1.57042283
168Tubulointerstitial nephritis (HP:0001970)1.56426194
169Abnormality of the ischium (HP:0003174)1.55816530
170Keratitis (HP:0000491)1.55784124
171Abnormality of the alveolar ridges (HP:0006477)1.55744430

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK123.14961247
2FGFR43.12743284
3FGFR23.11346213
4MAP4K13.07717213
5FRK3.07068893
6JAK33.00905566
7FGFR32.56662521
8TYK22.43412684
9MAP3K102.42890066
10MAP3K142.39263084
11TXK2.30385576
12CHUK2.25602851
13JAK12.20342631
14EPHA32.19344046
15ITK2.14476555
16MAP4K22.13415276
17TRIB31.84855457
18ACVR1B1.78031345
19IKBKB1.77047856
20IKBKE1.74806346
21CAMK1G1.71102600
22ZAP701.70537892
23PDGFRA1.66090311
24PAK31.63899100
25AKT31.57506580
26SIK31.57278253
27ADRBK21.56391433
28MAP3K131.52670022
29FGFR11.50818624
30ERBB31.50508787
31MAPK131.50283030
32CAMK1D1.48446838
33TNIK1.44699405
34TBK11.42991130
35CASK1.40540034
36BRD41.38138870
37STK101.37618793
38CAMKK21.37431672
39DMPK1.37114485
40IRAK41.36138890
41PDGFRB1.34723981
42TYRO31.33108503
43SIK21.32411163
44GRK61.32064246
45BCR1.29828258
46EEF2K1.29023389
47KIT1.23361637
48SIK11.22217178
49HCK1.19704488
50PTK61.18285146
51WNK31.17886799
52RPS6KA41.16775826
53NLK1.12939094
54LCK1.11560290
55MAP3K41.10830697
56FES1.10250674
57PINK11.10162678
58GRK71.09639278
59TRPM71.09367732
60PIK3CA1.08499047
61LATS11.06223119
62SYK1.02480567
63MKNK21.02149222
64IRAK20.99803043
65TTN0.99450875
66PKN20.97036473
67TEC0.95758503
68MAP3K70.95001860
69TGFBR20.94631385
70BTK0.94179908
71MARK10.93652119
72BMPR1B0.93371698
73NUAK10.92025201
74CSK0.89103452
75SGK20.88245854
76KDR0.86021632
77PIK3CG0.85887885
78EPHB10.84756014
79LRRK20.84664425
80JAK20.84363982
81MTOR0.83982535
82IRAK10.82365624
83CSF1R0.81876829
84CDK60.81782347
85BLK0.80868508
86STK30.77930581
87STK240.77500592
88RET0.77241932
89CDK90.76906259
90PIM10.76891328
91ERN10.73437198
92DYRK1A0.73343683
93INSRR0.71000259
94PRKD20.68703537
95FLT30.67934477
96TNK20.66239095
97PRKCH0.65865394
98ICK0.65753509
99HIPK20.65366247
100MARK20.64856393
101GRK10.63255064
102EPHB20.62310941
103CDK40.60482994
104SGK30.60089405
105RIPK10.60025279
106PRKCE0.58568093
107NEK90.58335283
108BMX0.54247616
109EGFR0.53914855
110MATK0.53251149
111WNK10.53130924
112NEK20.51206541
113STK380.50838768
114CDK30.50612543
115STK38L0.49453266
116TGFBR10.48483595
117MAPK70.48271482
118PRKAA20.48118257
119MARK30.47986881
120PASK0.47850205
121CDC42BPA0.47060792
122MST40.46968470
123PRKD10.46804043
124OBSCN0.46130787
125KSR10.46130448
126IGF1R0.45816396
127NTRK20.45139178
128PTK20.44578323
129DYRK1B0.44018670
130ALK0.43219620
131INSR0.42668427
132TAOK30.41396562
133CAMK40.41284572
134EPHA40.41262479
135TAOK10.40485826
136STK390.40481075
137EIF2AK30.39488349
138MELK0.39382693
139RPS6KA10.39212630
140* PRKCQ0.38118784
141ATR0.37484764
142LYN0.37147286
143CLK10.36840222
144MAPKAPK20.36469370
145DDR20.36198683
146STK40.35759031

Predicted pathways (KEGG)

RankGene SetZ-score
1NF-kappa B signaling pathway_Homo sapiens_hsa040642.39622772
2Primary immunodeficiency_Homo sapiens_hsa053402.30277030
3* T cell receptor signaling pathway_Homo sapiens_hsa046602.23910092
4Osteoclast differentiation_Homo sapiens_hsa043801.89596964
5B cell receptor signaling pathway_Homo sapiens_hsa046621.88578687
6Leishmaniasis_Homo sapiens_hsa051401.87199904
7* Measles_Homo sapiens_hsa051621.86473551
8Viral myocarditis_Homo sapiens_hsa054161.78356466
9Toxoplasmosis_Homo sapiens_hsa051451.78000693
10Allograft rejection_Homo sapiens_hsa053301.72552644
11Intestinal immune network for IgA production_Homo sapiens_hsa046721.69171374
12Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.67749850
13* Chronic myeloid leukemia_Homo sapiens_hsa052201.59154732
14Rheumatoid arthritis_Homo sapiens_hsa053231.58898950
15Jak-STAT signaling pathway_Homo sapiens_hsa046301.55731154
16Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.53726823
17Graft-versus-host disease_Homo sapiens_hsa053321.52948626
18Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.51997065
19TNF signaling pathway_Homo sapiens_hsa046681.50321364
20Acute myeloid leukemia_Homo sapiens_hsa052211.47740247
21Small cell lung cancer_Homo sapiens_hsa052221.44452914
22Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.42578943
23Toll-like receptor signaling pathway_Homo sapiens_hsa046201.42437261
24NOD-like receptor signaling pathway_Homo sapiens_hsa046211.42139039
25Antigen processing and presentation_Homo sapiens_hsa046121.41364570
26Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.40716741
27AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.36778043
28Pancreatic cancer_Homo sapiens_hsa052121.35614135
29Basal cell carcinoma_Homo sapiens_hsa052171.33602238
30Herpes simplex infection_Homo sapiens_hsa051681.32055378
31Hepatitis B_Homo sapiens_hsa051611.30842135
32MicroRNAs in cancer_Homo sapiens_hsa052061.30685832
33Circadian rhythm_Homo sapiens_hsa047101.27289234
34Shigellosis_Homo sapiens_hsa051311.26626993
35Apoptosis_Homo sapiens_hsa042101.25998435
36Chemokine signaling pathway_Homo sapiens_hsa040621.25673005
37Neurotrophin signaling pathway_Homo sapiens_hsa047221.24830568
38Notch signaling pathway_Homo sapiens_hsa043301.24743628
39RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.24575042
40Colorectal cancer_Homo sapiens_hsa052101.24353792
41HTLV-I infection_Homo sapiens_hsa051661.23580480
42Influenza A_Homo sapiens_hsa051641.19040004
43Transcriptional misregulation in cancer_Homo sapiens_hsa052021.18726735
44Prolactin signaling pathway_Homo sapiens_hsa049171.17127926
45Leukocyte transendothelial migration_Homo sapiens_hsa046701.13846887
46* Proteoglycans in cancer_Homo sapiens_hsa052051.11334909
47Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.11283270
48* Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.09002338
49Hematopoietic cell lineage_Homo sapiens_hsa046401.08089578
50Autoimmune thyroid disease_Homo sapiens_hsa053201.05729038
51Non-small cell lung cancer_Homo sapiens_hsa052231.05505998
52Adherens junction_Homo sapiens_hsa045201.04512355
53Thyroid hormone signaling pathway_Homo sapiens_hsa049191.03742578
54Prostate cancer_Homo sapiens_hsa052151.02691150
55Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.99648876
56Endometrial cancer_Homo sapiens_hsa052130.97870013
57Tuberculosis_Homo sapiens_hsa051520.97023914
58Epstein-Barr virus infection_Homo sapiens_hsa051690.96490866
59mTOR signaling pathway_Homo sapiens_hsa041500.96443145
60Hedgehog signaling pathway_Homo sapiens_hsa043400.95509209
61Viral carcinogenesis_Homo sapiens_hsa052030.94656846
62* Pathways in cancer_Homo sapiens_hsa052000.94200927
63VEGF signaling pathway_Homo sapiens_hsa043700.93777349
64Lysine degradation_Homo sapiens_hsa003100.93315435
65Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.91451423
66Phototransduction_Homo sapiens_hsa047440.89357589
67Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.89308223
68Renal cell carcinoma_Homo sapiens_hsa052110.86591559
69MAPK signaling pathway_Homo sapiens_hsa040100.85381566
70Platelet activation_Homo sapiens_hsa046110.83787413
71Malaria_Homo sapiens_hsa051440.83542183
72Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.82451997
73Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.82247189
74Focal adhesion_Homo sapiens_hsa045100.81693652
75Type II diabetes mellitus_Homo sapiens_hsa049300.81171513
76Hepatitis C_Homo sapiens_hsa051600.80676176
77Regulation of actin cytoskeleton_Homo sapiens_hsa048100.80042894
78Linoleic acid metabolism_Homo sapiens_hsa005910.79423615
79Glioma_Homo sapiens_hsa052140.79043524
80Insulin resistance_Homo sapiens_hsa049310.77606282
81ABC transporters_Homo sapiens_hsa020100.77579897
82Pertussis_Homo sapiens_hsa051330.75524760
83TGF-beta signaling pathway_Homo sapiens_hsa043500.74495795
84Protein export_Homo sapiens_hsa030600.72123298
85Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.71982573
86Legionellosis_Homo sapiens_hsa051340.71231925
87Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.71175623
88Staphylococcus aureus infection_Homo sapiens_hsa051500.71068302
89FoxO signaling pathway_Homo sapiens_hsa040680.70838536
90HIF-1 signaling pathway_Homo sapiens_hsa040660.70704987
91Adipocytokine signaling pathway_Homo sapiens_hsa049200.68324938
92Hippo signaling pathway_Homo sapiens_hsa043900.67856714
93Ras signaling pathway_Homo sapiens_hsa040140.67563900
94Wnt signaling pathway_Homo sapiens_hsa043100.65632372
95alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.65579079
96Axon guidance_Homo sapiens_hsa043600.65224111
97Rap1 signaling pathway_Homo sapiens_hsa040150.64507165
98Asthma_Homo sapiens_hsa053100.64465239
99p53 signaling pathway_Homo sapiens_hsa041150.64238299
100Salmonella infection_Homo sapiens_hsa051320.64061339
101Phosphatidylinositol signaling system_Homo sapiens_hsa040700.63358478
102Type I diabetes mellitus_Homo sapiens_hsa049400.63106414
103Central carbon metabolism in cancer_Homo sapiens_hsa052300.62780592
104Ether lipid metabolism_Homo sapiens_hsa005650.62675024
105Amoebiasis_Homo sapiens_hsa051460.62158681
106Dorso-ventral axis formation_Homo sapiens_hsa043200.61420430
107Longevity regulating pathway - mammal_Homo sapiens_hsa042110.61049667
108Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.60995156
109Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.60631131
110Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.59743380
111Choline metabolism in cancer_Homo sapiens_hsa052310.59246527
112Basal transcription factors_Homo sapiens_hsa030220.56931214
113African trypanosomiasis_Homo sapiens_hsa051430.56890115
114Cholinergic synapse_Homo sapiens_hsa047250.56672755
115Vascular smooth muscle contraction_Homo sapiens_hsa042700.55714078
116* Endocytosis_Homo sapiens_hsa041440.54146817
117Dilated cardiomyopathy_Homo sapiens_hsa054140.53146422
118cAMP signaling pathway_Homo sapiens_hsa040240.52739660
119Regulation of autophagy_Homo sapiens_hsa041400.52580400
120Taste transduction_Homo sapiens_hsa047420.52068872
121Melanoma_Homo sapiens_hsa052180.51872076
122* ErbB signaling pathway_Homo sapiens_hsa040120.51866739
123Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.51069319
124PI3K-Akt signaling pathway_Homo sapiens_hsa041510.50842725
125Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.50618063
126Mineral absorption_Homo sapiens_hsa049780.49816981
127Aldosterone synthesis and secretion_Homo sapiens_hsa049250.45523588
128Renin secretion_Homo sapiens_hsa049240.41778170
129Nitrogen metabolism_Homo sapiens_hsa009100.37344529
130Sphingolipid signaling pathway_Homo sapiens_hsa040710.34962556
131Olfactory transduction_Homo sapiens_hsa047400.34775245
132Inositol phosphate metabolism_Homo sapiens_hsa005620.33018744
133Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.32940083

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »