Rank | Gene Set | Z-score |
---|---|---|
1 | negative thymic T cell selection (GO:0045060) | 5.19434324 |
2 | negative T cell selection (GO:0043383) | 5.06266279 |
3 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.02908958 |
4 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 4.84446791 |
5 | cytidine deamination (GO:0009972) | 4.72373853 |
6 | cytidine metabolic process (GO:0046087) | 4.72373853 |
7 | cytidine catabolic process (GO:0006216) | 4.72373853 |
8 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 4.64566930 |
9 | NIK/NF-kappaB signaling (GO:0038061) | 4.56898172 |
10 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.46056978 |
11 | negative regulation of cell killing (GO:0031342) | 4.46056978 |
12 | activated T cell proliferation (GO:0050798) | 4.38015064 |
13 | regulation of lymphocyte chemotaxis (GO:1901623) | 4.35961337 |
14 | positive thymic T cell selection (GO:0045059) | 4.18449194 |
15 | thymic T cell selection (GO:0045061) | 4.17347817 |
16 | regulation of gamma-delta T cell differentiation (GO:0045586) | 4.02523552 |
17 | regulation of T cell chemotaxis (GO:0010819) | 3.99251277 |
18 | positive regulation of T cell chemotaxis (GO:0010820) | 3.99251277 |
19 | T cell selection (GO:0045058) | 3.90486311 |
20 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.82106542 |
21 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.82106542 |
22 | regulation of gamma-delta T cell activation (GO:0046643) | 3.81300358 |
23 | positive regulation of calcium-mediated signaling (GO:0050850) | 3.80383825 |
24 | positive T cell selection (GO:0043368) | 3.64623868 |
25 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.60984730 |
26 | negative regulation by host of viral transcription (GO:0043922) | 3.56976478 |
27 | establishment of protein localization to Golgi (GO:0072600) | 3.46968834 |
28 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.46422737 |
29 | interferon-gamma production (GO:0032609) | 3.43629831 |
30 | neural tube formation (GO:0001841) | 3.39266225 |
31 | regulation of chemokine-mediated signaling pathway (GO:0070099) | 3.35268627 |
32 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.33651969 |
33 | growth hormone receptor signaling pathway (GO:0060396) | 3.33498842 |
34 | protein targeting to Golgi (GO:0000042) | 3.33131244 |
35 | response to interleukin-15 (GO:0070672) | 3.32623084 |
36 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 3.27428872 |
37 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.26536430 |
38 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 3.25897137 |
39 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.25746372 |
40 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.25603250 |
41 | cytoplasmic mRNA processing body assembly (GO:0033962) | 3.25275311 |
42 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.20817774 |
43 | DNA deamination (GO:0045006) | 3.19122989 |
44 | dopaminergic neuron differentiation (GO:0071542) | 3.16149737 |
45 | JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397) | 3.07711914 |
46 | eosinophil chemotaxis (GO:0048245) | 3.03897634 |
47 | regulation of regulatory T cell differentiation (GO:0045589) | 3.01644440 |
48 | retrograde transport, vesicle recycling within Golgi (GO:0000301) | 3.00220942 |
49 | regulation of B cell differentiation (GO:0045577) | 2.98948929 |
50 | myeloid dendritic cell differentiation (GO:0043011) | 2.98669187 |
51 | tolerance induction (GO:0002507) | 2.98269225 |
52 | cell proliferation involved in metanephros development (GO:0072203) | 2.95348019 |
53 | cellular response to interleukin-15 (GO:0071350) | 2.94509051 |
54 | positive regulation of granulocyte differentiation (GO:0030854) | 2.94498567 |
55 | T cell migration (GO:0072678) | 2.93819443 |
56 | regulation of B cell receptor signaling pathway (GO:0050855) | 2.91118358 |
57 | positive regulation of lymphocyte migration (GO:2000403) | 2.90201886 |
58 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.88518910 |
59 | regulation of calcium-mediated signaling (GO:0050848) | 2.87696474 |
60 | positive regulation of defense response to virus by host (GO:0002230) | 2.87251113 |
61 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 2.86464174 |
62 | pre-miRNA processing (GO:0031054) | 2.85122758 |
63 | cellular response to growth hormone stimulus (GO:0071378) | 2.84174789 |
64 | myeloid dendritic cell activation (GO:0001773) | 2.82959497 |
65 | regulation of chronic inflammatory response (GO:0002676) | 2.81981869 |
66 | radial glial cell differentiation (GO:0060019) | 2.81382364 |
67 | positive regulation of developmental pigmentation (GO:0048087) | 2.78242202 |
68 | positive regulation of interleukin-2 production (GO:0032743) | 2.77541422 |
69 | lateral sprouting from an epithelium (GO:0060601) | 2.73713325 |
70 | negative regulation of neurotransmitter secretion (GO:0046929) | 2.73106816 |
71 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 2.73035513 |
72 | regulation of translation, ncRNA-mediated (GO:0045974) | 2.73035513 |
73 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 2.73035513 |
74 | T cell costimulation (GO:0031295) | 2.72842687 |
75 | T-helper cell differentiation (GO:0042093) | 2.72830179 |
76 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 2.72830179 |
77 | peripheral nervous system neuron development (GO:0048935) | 2.68876509 |
78 | eosinophil migration (GO:0072677) | 2.66961107 |
79 | * NLS-bearing protein import into nucleus (GO:0006607) | 2.66603725 |
80 | positive regulation of humoral immune response (GO:0002922) | 2.66557501 |
81 | lymphocyte costimulation (GO:0031294) | 2.66474253 |
82 | * regulation of T cell receptor signaling pathway (GO:0050856) | 2.66013656 |
83 | positive regulation of isotype switching (GO:0045830) | 2.63126646 |
84 | tyrosine phosphorylation of STAT protein (GO:0007260) | 2.62459145 |
85 | T cell receptor signaling pathway (GO:0050852) | 2.62300575 |
86 | regulation of mononuclear cell migration (GO:0071675) | 2.61593238 |
87 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 2.59379321 |
88 | positive regulation of histone deacetylation (GO:0031065) | 2.59155679 |
89 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.58117574 |
90 | histone H3-K4 trimethylation (GO:0080182) | 2.57935122 |
91 | positive regulation of cell killing (GO:0031343) | 2.57425196 |
92 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 2.56450430 |
93 | leukocyte aggregation (GO:0070486) | 2.56108982 |
94 | metanephric mesenchyme development (GO:0072075) | 2.55349626 |
95 | regulation of cell killing (GO:0031341) | 2.54857921 |
96 | negative regulation of B cell activation (GO:0050869) | 2.54670680 |
97 | T cell differentiation (GO:0030217) | 2.54277614 |
98 | positive regulation of natural killer cell differentiation (GO:0032825) | 2.53901601 |
99 | positive regulation of B cell differentiation (GO:0045579) | 2.53661744 |
100 | B cell homeostasis (GO:0001782) | 2.53124582 |
101 | negative regulation of B cell proliferation (GO:0030889) | 2.53066523 |
102 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 2.53034874 |
103 | * regulation of alpha-beta T cell proliferation (GO:0046640) | 2.52902371 |
104 | mitotic sister chromatid cohesion (GO:0007064) | 2.49430607 |
105 | positive regulation of lymphocyte apoptotic process (GO:0070230) | 2.47421425 |
106 | mesenchymal-epithelial cell signaling (GO:0060638) | 2.47273502 |
107 | fibroblast migration (GO:0010761) | 2.47157016 |
108 | * regulation of T cell tolerance induction (GO:0002664) | 2.46953716 |
109 | regulation of pigment cell differentiation (GO:0050932) | 2.46864147 |
110 | antigen receptor-mediated signaling pathway (GO:0050851) | 2.46423006 |
111 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.46175994 |
112 | histone H3-K36 demethylation (GO:0070544) | 2.42865740 |
113 | negative regulation of T cell mediated immunity (GO:0002710) | 2.42270261 |
114 | T cell differentiation involved in immune response (GO:0002292) | 2.41842057 |
115 | alpha-beta T cell differentiation involved in immune response (GO:0002293) | 2.41842057 |
116 | alpha-beta T cell activation involved in immune response (GO:0002287) | 2.41842057 |
117 | alpha-beta T cell activation (GO:0046631) | 2.41466713 |
118 | limb development (GO:0060173) | 2.41446279 |
119 | appendage development (GO:0048736) | 2.41446279 |
120 | positive regulation of leukocyte apoptotic process (GO:2000108) | 2.41176701 |
121 | monocyte chemotaxis (GO:0002548) | 2.40963292 |
122 | B cell receptor signaling pathway (GO:0050853) | 2.40309679 |
123 | negative regulation of T-helper cell differentiation (GO:0045623) | 2.39535261 |
124 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 2.39535261 |
125 | cell proliferation involved in kidney development (GO:0072111) | 2.39312902 |
126 | regulation of thymocyte apoptotic process (GO:0070243) | 2.38234563 |
127 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 2.38229490 |
128 | behavioral response to nicotine (GO:0035095) | 2.38060492 |
129 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 2.37665925 |
130 | histone H3-K4 methylation (GO:0051568) | 2.36359968 |
131 | germinal center formation (GO:0002467) | 2.35498824 |
132 | T cell proliferation (GO:0042098) | 2.35261728 |
133 | CD4-positive, alpha-beta T cell differentiation (GO:0043367) | 2.34543431 |
134 | regulation of lymphocyte migration (GO:2000401) | 2.34332838 |
135 | response to muramyl dipeptide (GO:0032495) | 2.32088543 |
136 | response to prostaglandin E (GO:0034695) | 2.31757265 |
137 | T cell homeostasis (GO:0043029) | 2.31684544 |
138 | embryonic hemopoiesis (GO:0035162) | 2.30775863 |
139 | nuclear pore complex assembly (GO:0051292) | 2.29368557 |
140 | heterotypic cell-cell adhesion (GO:0034113) | 2.27775157 |
141 | alpha-beta T cell differentiation (GO:0046632) | 2.26620612 |
142 | * regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 2.26583457 |
143 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors (GO:1902043) | 2.25059419 |
144 | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr | 2.25027694 |
145 | neutrophil activation (GO:0042119) | 2.24902445 |
146 | regulation of natural killer cell mediated immunity (GO:0002715) | 2.24336325 |
147 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 2.24336325 |
148 | B cell proliferation (GO:0042100) | 2.24138421 |
149 | positive regulation of B cell proliferation (GO:0030890) | 2.24034378 |
150 | lymphocyte homeostasis (GO:0002260) | 2.23236608 |
151 | regulation of NFAT protein import into nucleus (GO:0051532) | 2.21875788 |
152 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 2.21874569 |
153 | positive regulation of T cell cytokine production (GO:0002726) | 2.21871867 |
154 | natural killer cell mediated cytotoxicity (GO:0042267) | 2.21565085 |
155 | natural killer cell mediated immunity (GO:0002228) | 2.21565085 |
156 | natural killer cell differentiation (GO:0001779) | 2.21132620 |
157 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 2.20819776 |
158 | positive regulation of T cell apoptotic process (GO:0070234) | 2.20777571 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 7.00316495 |
2 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 5.11461062 |
3 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 4.73609386 |
4 | * NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 4.23711002 |
5 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.76052890 |
6 | * STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.24825098 |
7 | MYC_22102868_ChIP-Seq_BL_Human | 3.01525097 |
8 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.95805435 |
9 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.94041688 |
10 | * FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.70859515 |
11 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.70376839 |
12 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.64520922 |
13 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.59160862 |
14 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 2.57314293 |
15 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.45124944 |
16 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.31225199 |
17 | TCF7_22412390_ChIP-Seq_EML_Mouse | 2.30850186 |
18 | MAF_26560356_Chip-Seq_TH1_Human | 2.30109296 |
19 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.29435541 |
20 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 2.26910897 |
21 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 2.25238594 |
22 | * MYB_26560356_Chip-Seq_TH2_Human | 2.22494591 |
23 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.21430324 |
24 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 2.17881432 |
25 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.17517764 |
26 | * ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.13437783 |
27 | KDM2B_26808549_Chip-Seq_DND41_Human | 2.12558908 |
28 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.11912788 |
29 | * STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.11431796 |
30 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.09157335 |
31 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.08278496 |
32 | MYB_26560356_Chip-Seq_TH1_Human | 2.05349394 |
33 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.04478750 |
34 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.01711234 |
35 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.00254568 |
36 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.99995253 |
37 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.99401876 |
38 | * POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.98336713 |
39 | * PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.98036201 |
40 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.97777279 |
41 | VDR_22108803_ChIP-Seq_LS180_Human | 1.93280018 |
42 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.91650275 |
43 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.89116621 |
44 | UTX_26944678_Chip-Seq_JUKART_Human | 1.88120906 |
45 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.84381584 |
46 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.83803254 |
47 | * VDR_24763502_ChIP-Seq_THP-1_Human | 1.78180153 |
48 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.63458725 |
49 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.63145546 |
50 | FUS_26573619_Chip-Seq_HEK293_Human | 1.59717469 |
51 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.59552562 |
52 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.59127031 |
53 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.58862705 |
54 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.58557565 |
55 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.58136928 |
56 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.57488149 |
57 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.57444946 |
58 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.56582485 |
59 | SPI1_23127762_ChIP-Seq_K562_Human | 1.55894714 |
60 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.54126668 |
61 | * P300_19829295_ChIP-Seq_ESCs_Human | 1.53499879 |
62 | * AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.50967501 |
63 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.48914199 |
64 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.48164771 |
65 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.47961585 |
66 | * E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.46729325 |
67 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.44242823 |
68 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.42116950 |
69 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.41973641 |
70 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.40150823 |
71 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.37312523 |
72 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.37099161 |
73 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.36876872 |
74 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.36260673 |
75 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.36121467 |
76 | * BCAT_22108803_ChIP-Seq_LS180_Human | 1.35637446 |
77 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.35394617 |
78 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.32946200 |
79 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.32676972 |
80 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.32676972 |
81 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.31681333 |
82 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.31043461 |
83 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.30950558 |
84 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.30384113 |
85 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.29838700 |
86 | * CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.28840523 |
87 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.28341341 |
88 | * OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.28275422 |
89 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.28147282 |
90 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.28042656 |
91 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.27639445 |
92 | MAF_26560356_Chip-Seq_TH2_Human | 1.27585090 |
93 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.27582702 |
94 | * SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.25867464 |
95 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.25731368 |
96 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.25251367 |
97 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.25194329 |
98 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.25060222 |
99 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.24586601 |
100 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.24404733 |
101 | * STAT3_23295773_ChIP-Seq_U87_Human | 1.24097005 |
102 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.23734843 |
103 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.23595089 |
104 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.21806759 |
105 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.21093394 |
106 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.20607189 |
107 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.20549792 |
108 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.19521009 |
109 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.18162915 |
110 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.17831512 |
111 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.17803534 |
112 | FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 1.17080474 |
113 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.16715072 |
114 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.15890131 |
115 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.15552416 |
116 | * AR_25329375_ChIP-Seq_VCAP_Human | 1.15338772 |
117 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.15309362 |
118 | * TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.14823139 |
119 | * SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.12241884 |
120 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.12184001 |
121 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.11685730 |
122 | * IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.08570299 |
123 | * CBP_20019798_ChIP-Seq_JUKART_Human | 1.08570299 |
124 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.08354624 |
125 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.08125060 |
126 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.07031800 |
127 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.06788559 |
128 | BRD4_25478319_ChIP-Seq_HGPS_Human | 1.06382261 |
129 | TCF4_23295773_ChIP-Seq_U87_Human | 1.06215028 |
130 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.04960240 |
131 | TP53_16413492_ChIP-PET_HCT116_Human | 1.04555449 |
132 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.04493693 |
133 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.03670256 |
134 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.03490243 |
135 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.03230578 |
136 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.03010439 |
137 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.01711510 |
138 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.01364440 |
139 | * TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.00043069 |
140 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 0.99928627 |
141 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.99694838 |
142 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.98467581 |
143 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.97605284 |
144 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.97540800 |
145 | * TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.96552638 |
146 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.96197883 |
147 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 0.95884999 |
148 | * RUNX2_22187159_ChIP-Seq_PCA_Human | 0.95250553 |
149 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.95133681 |
150 | TP53_18474530_ChIP-ChIP_U2OS_Human | 0.94735106 |
151 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 0.94671789 |
152 | * FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.91114888 |
153 | KDM2B_26808549_Chip-Seq_K562_Human | 0.90236826 |
154 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 0.87662994 |
155 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 0.86648614 |
156 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 0.86115056 |
157 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.85583280 |
158 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 0.85241792 |
159 | * CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.83551545 |
160 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.81935502 |
161 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.81630530 |
162 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 0.81371641 |
163 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 0.81371641 |
164 | * ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.81168396 |
165 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.80799733 |
166 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.78405776 |
167 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.78284887 |
168 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.77079083 |
169 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.76988905 |
170 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.74714887 |
171 | FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 0.74714316 |
172 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 0.74219938 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0000569_abnormal_digit_pigmentation | 4.53286749 |
2 | MP0003011_delayed_dark_adaptation | 3.13655850 |
3 | MP0002166_altered_tumor_susceptibility | 2.99108242 |
4 | MP0003763_abnormal_thymus_physiology | 2.71700667 |
5 | MP0001835_abnormal_antigen_presentation | 2.68680751 |
6 | MP0000685_abnormal_immune_system | 2.58761366 |
7 | MP0005387_immune_system_phenotype | 2.46329897 |
8 | MP0001790_abnormal_immune_system | 2.46329897 |
9 | MP0000372_irregular_coat_pigmentation | 2.42477708 |
10 | MP0003300_gastrointestinal_ulcer | 2.34592882 |
11 | MP0002006_tumorigenesis | 2.31215660 |
12 | MP0004510_myositis | 2.30623960 |
13 | MP0001800_abnormal_humoral_immune | 2.27432421 |
14 | MP0005671_abnormal_response_to | 2.26172997 |
15 | MP0002638_abnormal_pupillary_reflex | 2.08768602 |
16 | MP0003436_decreased_susceptibility_to | 2.03167242 |
17 | MP0003303_peritoneal_inflammation | 2.02855210 |
18 | MP0002396_abnormal_hematopoietic_system | 1.95821134 |
19 | MP0003950_abnormal_plasma_membrane | 1.95075089 |
20 | MP0005076_abnormal_cell_differentiation | 1.93305681 |
21 | MP0002138_abnormal_hepatobiliary_system | 1.92729463 |
22 | MP0003045_fibrosis | 1.87718316 |
23 | MP0002009_preneoplasia | 1.86232232 |
24 | MP0002452_abnormal_antigen_presenting | 1.86131776 |
25 | MP0004381_abnormal_hair_follicle | 1.83477164 |
26 | MP0004808_abnormal_hematopoietic_stem | 1.82758209 |
27 | * MP0002398_abnormal_bone_marrow | 1.79645036 |
28 | * MP0005000_abnormal_immune_tolerance | 1.79387751 |
29 | MP0000703_abnormal_thymus_morphology | 1.78332039 |
30 | MP0002277_abnormal_respiratory_mucosa | 1.73870452 |
31 | * MP0002723_abnormal_immune_serum | 1.73681021 |
32 | * MP0002420_abnormal_adaptive_immunity | 1.72698170 |
33 | * MP0001819_abnormal_immune_cell | 1.72249287 |
34 | MP0002405_respiratory_system_inflammati | 1.68053269 |
35 | MP0005503_abnormal_tendon_morphology | 1.64270628 |
36 | MP0001873_stomach_inflammation | 1.62082656 |
37 | MP0005275_abnormal_skin_tensile | 1.61714615 |
38 | MP0002822_catalepsy | 1.60783997 |
39 | MP0003091_abnormal_cell_migration | 1.57757670 |
40 | MP0000733_abnormal_muscle_development | 1.55808384 |
41 | MP0001346_abnormal_lacrimal_gland | 1.55373948 |
42 | MP0000566_synostosis | 1.55036316 |
43 | * MP0000716_abnormal_immune_system | 1.54670305 |
44 | MP0004947_skin_inflammation | 1.53493675 |
45 | MP0005253_abnormal_eye_physiology | 1.51598543 |
46 | MP0010352_gastrointestinal_tract_polyps | 1.51118636 |
47 | MP0009278_abnormal_bone_marrow | 1.41123982 |
48 | MP0003880_abnormal_central_pattern | 1.39316205 |
49 | MP0006072_abnormal_retinal_apoptosis | 1.37039987 |
50 | MP0002722_abnormal_immune_system | 1.34088950 |
51 | MP0001984_abnormal_olfaction | 1.30946156 |
52 | MP0001502_abnormal_circadian_rhythm | 1.29914862 |
53 | MP0008961_abnormal_basal_metabolism | 1.29898259 |
54 | MP0000689_abnormal_spleen_morphology | 1.29845101 |
55 | MP0005187_abnormal_penis_morphology | 1.27998619 |
56 | MP0002254_reproductive_system_inflammat | 1.27049406 |
57 | MP0010307_abnormal_tumor_latency | 1.25538462 |
58 | MP0003183_abnormal_peptide_metabolism | 1.24616231 |
59 | MP0002933_joint_inflammation | 1.24517100 |
60 | MP0001299_abnormal_eye_distance/ | 1.23695680 |
61 | MP0002938_white_spotting | 1.23487479 |
62 | MP0001348_abnormal_lacrimal_gland | 1.20562550 |
63 | MP0010386_abnormal_urinary_bladder | 1.20519173 |
64 | MP0003705_abnormal_hypodermis_morpholog | 1.20231055 |
65 | * MP0002429_abnormal_blood_cell | 1.20065109 |
66 | MP0005025_abnormal_response_to | 1.20031528 |
67 | MP0005645_abnormal_hypothalamus_physiol | 1.19282270 |
68 | MP0000778_abnormal_nervous_system | 1.18404376 |
69 | MP0002168_other_aberrant_phenotype | 1.17963870 |
70 | MP0000427_abnormal_hair_cycle | 1.17378427 |
71 | MP0003866_abnormal_defecation | 1.16087680 |
72 | MP0009333_abnormal_splenocyte_physiolog | 1.15608550 |
73 | MP0002998_abnormal_bone_remodeling | 1.14121760 |
74 | MP0002928_abnormal_bile_duct | 1.13603120 |
75 | MP0005075_abnormal_melanosome_morpholog | 1.13336738 |
76 | MP0002102_abnormal_ear_morphology | 1.12555764 |
77 | MP0004742_abnormal_vestibular_system | 1.11930173 |
78 | MP0004145_abnormal_muscle_electrophysio | 1.11898046 |
79 | MP0008789_abnormal_olfactory_epithelium | 1.10892364 |
80 | MP0005174_abnormal_tail_pigmentation | 1.10618969 |
81 | MP0002163_abnormal_gland_morphology | 1.09672187 |
82 | MP0001853_heart_inflammation | 1.08903527 |
83 | MP0000538_abnormal_urinary_bladder | 1.08542186 |
84 | MP0002837_dystrophic_cardiac_calcinosis | 1.08161418 |
85 | MP0010155_abnormal_intestine_physiology | 1.07668860 |
86 | MP0003448_altered_tumor_morphology | 1.07539137 |
87 | MP0002419_abnormal_innate_immunity | 1.07513238 |
88 | MP0000371_diluted_coat_color | 1.07475540 |
89 | MP0008995_early_reproductive_senescence | 1.04344624 |
90 | MP0002148_abnormal_hypersensitivity_rea | 1.03022963 |
91 | MP0000428_abnormal_craniofacial_morphol | 1.01791083 |
92 | MP0002653_abnormal_ependyma_morphology | 1.01779236 |
93 | MP0002751_abnormal_autonomic_nervous | 1.01242713 |
94 | MP0001501_abnormal_sleep_pattern | 1.01200234 |
95 | MP0005257_abnormal_intraocular_pressure | 1.01003591 |
96 | MP0010030_abnormal_orbit_morphology | 1.00167056 |
97 | MP0006276_abnormal_autonomic_nervous | 0.99567193 |
98 | MP0009785_altered_susceptibility_to | 0.95998346 |
99 | MP0008057_abnormal_DNA_replication | 0.95676807 |
100 | MP0001188_hyperpigmentation | 0.95625410 |
101 | MP0003172_abnormal_lysosome_physiology | 0.94525228 |
102 | MP0001293_anophthalmia | 0.92259074 |
103 | MP0000767_abnormal_smooth_muscle | 0.91193713 |
104 | MP0006082_CNS_inflammation | 0.89753394 |
105 | MP0001545_abnormal_hematopoietic_system | 0.89744004 |
106 | MP0005397_hematopoietic_system_phenotyp | 0.89744004 |
107 | MP0003567_abnormal_fetal_cardiomyocyte | 0.89375456 |
108 | MP0008438_abnormal_cutaneous_collagen | 0.89370642 |
109 | MP0006054_spinal_hemorrhage | 0.89022932 |
110 | MP0005408_hypopigmentation | 0.88694695 |
111 | MP0001533_abnormal_skeleton_physiology | 0.87348392 |
112 | MP0004134_abnormal_chest_morphology | 0.86110144 |
113 | MP0005390_skeleton_phenotype | 0.86101911 |
114 | MP0001119_abnormal_female_reproductive | 0.85273299 |
115 | MP0002925_abnormal_cardiovascular_devel | 0.84494273 |
116 | MP0000383_abnormal_hair_follicle | 0.84206725 |
117 | MP0005248_abnormal_Harderian_gland | 0.83719922 |
118 | MP0009250_abnormal_appendicular_skeleto | 0.83679595 |
119 | MP0001243_abnormal_dermal_layer | 0.82935820 |
120 | MP0005508_abnormal_skeleton_morphology | 0.82555904 |
121 | MP0001879_abnormal_lymphatic_vessel | 0.82459102 |
122 | MP0005310_abnormal_salivary_gland | 0.81744808 |
123 | MP0003566_abnormal_cell_adhesion | 0.81182125 |
124 | MP0005551_abnormal_eye_electrophysiolog | 0.80295666 |
125 | MP0000858_altered_metastatic_potential | 0.79828904 |
126 | MP0003279_aneurysm | 0.78799234 |
127 | MP0009764_decreased_sensitivity_to | 0.76108812 |
128 | MP0001845_abnormal_inflammatory_respons | 0.76058361 |
129 | MP0001958_emphysema | 0.75826151 |
130 | MP0003943_abnormal_hepatobiliary_system | 0.75524094 |
131 | MP0002932_abnormal_joint_morphology | 0.75491007 |
132 | MP0003942_abnormal_urinary_system | 0.75425268 |
133 | MP0000627_abnormal_mammary_gland | 0.75303908 |
134 | MP0000465_gastrointestinal_hemorrhage | 0.75160313 |
135 | MP0002282_abnormal_trachea_morphology | 0.74494585 |
136 | MP0000490_abnormal_crypts_of | 0.73721061 |
137 | MP0002109_abnormal_limb_morphology | 0.73073602 |
138 | MP0003453_abnormal_keratinocyte_physiol | 0.72407799 |
139 | MP0000537_abnormal_urethra_morphology | 0.71598939 |
140 | MP0010368_abnormal_lymphatic_system | 0.71545019 |
141 | MP0005023_abnormal_wound_healing | 0.70781416 |
142 | MP0001849_ear_inflammation | 0.70160937 |
143 | MP0002088_abnormal_embryonic_growth/wei | 0.69998585 |
144 | MP0004215_abnormal_myocardial_fiber | 0.68316404 |
145 | MP0000647_abnormal_sebaceous_gland | 0.67800442 |
146 | MP0005670_abnormal_white_adipose | 0.67114739 |
147 | MP0005379_endocrine/exocrine_gland_phen | 0.66358062 |
148 | MP0004084_abnormal_cardiac_muscle | 0.64693097 |
149 | MP0003724_increased_susceptibility_to | 0.64491206 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Short 4th metacarpal (HP:0010044) | 4.43893486 |
2 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 4.43893486 |
3 | Trigonocephaly (HP:0000243) | 3.92840149 |
4 | Abnormality of the fingertips (HP:0001211) | 3.88944180 |
5 | Abnormality of eosinophils (HP:0001879) | 3.56309056 |
6 | Abnormality of the parietal bone (HP:0002696) | 3.46393571 |
7 | Chronic diarrhea (HP:0002028) | 3.41593654 |
8 | Autoimmune hemolytic anemia (HP:0001890) | 3.34092314 |
9 | Midline defect of the nose (HP:0004122) | 3.27768210 |
10 | Thyroiditis (HP:0100646) | 3.25715275 |
11 | IgG deficiency (HP:0004315) | 3.21805278 |
12 | Abnormality of the renal cortex (HP:0011035) | 3.02870817 |
13 | Abnormality of the 4th metacarpal (HP:0010012) | 3.01652328 |
14 | Narrow palate (HP:0000189) | 2.86644950 |
15 | Pancreatic cysts (HP:0001737) | 2.78370522 |
16 | Increased density of long bones (HP:0006392) | 2.71590247 |
17 | Hyperventilation (HP:0002883) | 2.68375781 |
18 | Widely spaced teeth (HP:0000687) | 2.66266814 |
19 | T lymphocytopenia (HP:0005403) | 2.63538003 |
20 | Abnormality of T cell number (HP:0011839) | 2.61947969 |
21 | Chronic otitis media (HP:0000389) | 2.57700392 |
22 | Renal cortical cysts (HP:0000803) | 2.55326825 |
23 | Abnormality of the nasal septum (HP:0000419) | 2.54721732 |
24 | Increased IgM level (HP:0003496) | 2.54180342 |
25 | Recurrent viral infections (HP:0004429) | 2.53847619 |
26 | Recurrent fungal infections (HP:0002841) | 2.52453507 |
27 | Neoplasm of the heart (HP:0100544) | 2.47924426 |
28 | Shallow orbits (HP:0000586) | 2.47062922 |
29 | Neoplasm of the tracheobronchial system (HP:0100552) | 2.45692104 |
30 | Alveolar cell carcinoma (HP:0006519) | 2.42568304 |
31 | Broad metatarsal (HP:0001783) | 2.41666537 |
32 | Hemoptysis (HP:0002105) | 2.41509115 |
33 | Lymphopenia (HP:0001888) | 2.38389022 |
34 | Abnormality of the renal medulla (HP:0100957) | 2.38183541 |
35 | Long eyelashes (HP:0000527) | 2.35567621 |
36 | Gastrointestinal infarctions (HP:0005244) | 2.35329966 |
37 | Depressed nasal tip (HP:0000437) | 2.34942460 |
38 | Sparse lateral eyebrow (HP:0005338) | 2.34174294 |
39 | Anteriorly placed anus (HP:0001545) | 2.32118892 |
40 | Abnormality of incisor morphology (HP:0011063) | 2.31907280 |
41 | Broad face (HP:0000283) | 2.30232790 |
42 | Exostoses (HP:0100777) | 2.29952158 |
43 | Spinal cord lesions (HP:0100561) | 2.29423798 |
44 | Syringomyelia (HP:0003396) | 2.29423798 |
45 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.29014354 |
46 | Amyotrophic lateral sclerosis (HP:0007354) | 2.27910478 |
47 | Large earlobe (HP:0009748) | 2.27681646 |
48 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.24592302 |
49 | Nephronophthisis (HP:0000090) | 2.23172713 |
50 | Joint swelling (HP:0001386) | 2.22163547 |
51 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 2.21453984 |
52 | Supernumerary ribs (HP:0005815) | 2.20238466 |
53 | Aortic aneurysm (HP:0004942) | 2.15257701 |
54 | Encephalitis (HP:0002383) | 2.14493583 |
55 | Deep philtrum (HP:0002002) | 2.13627129 |
56 | Eczematoid dermatitis (HP:0000976) | 2.13621573 |
57 | Macroorchidism (HP:0000053) | 2.10151719 |
58 | Hypoproteinemia (HP:0003075) | 2.08919785 |
59 | Increased corneal curvature (HP:0100692) | 2.08451723 |
60 | Keratoconus (HP:0000563) | 2.08451723 |
61 | Combined immunodeficiency (HP:0005387) | 2.07498796 |
62 | Peritonitis (HP:0002586) | 2.06465975 |
63 | Limited elbow extension (HP:0001377) | 2.06259531 |
64 | Abnormality of the prostate (HP:0008775) | 2.05762066 |
65 | Molar tooth sign on MRI (HP:0002419) | 2.04717421 |
66 | Abnormality of midbrain morphology (HP:0002418) | 2.04717421 |
67 | Cerebral aneurysm (HP:0004944) | 2.03440608 |
68 | Adactyly (HP:0009776) | 2.03029643 |
69 | Tubular atrophy (HP:0000092) | 2.02617033 |
70 | Abnormality of the peritoneum (HP:0002585) | 2.02019052 |
71 | Chronic hepatic failure (HP:0100626) | 2.00297948 |
72 | Recurrent bronchitis (HP:0002837) | 1.99937117 |
73 | Aplasia cutis congenita (HP:0001057) | 1.99601669 |
74 | Mediastinal lymphadenopathy (HP:0100721) | 1.99456155 |
75 | Hematochezia (HP:0002573) | 1.99023815 |
76 | Volvulus (HP:0002580) | 1.98797036 |
77 | Myositis (HP:0100614) | 1.98420344 |
78 | Congenital stationary night blindness (HP:0007642) | 1.94643343 |
79 | Stomach cancer (HP:0012126) | 1.94615490 |
80 | Persistence of primary teeth (HP:0006335) | 1.94429991 |
81 | Bronchitis (HP:0012387) | 1.93413224 |
82 | Arterial thrombosis (HP:0004420) | 1.93392876 |
83 | Intestinal atresia (HP:0011100) | 1.93161491 |
84 | Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658) | 1.92929176 |
85 | Nasal polyposis (HP:0100582) | 1.92627402 |
86 | Hypoplastic labia majora (HP:0000059) | 1.92241667 |
87 | Autoimmune thrombocytopenia (HP:0001973) | 1.91624796 |
88 | Meningitis (HP:0001287) | 1.91307202 |
89 | Panhypogammaglobulinemia (HP:0003139) | 1.89965872 |
90 | Periodontitis (HP:0000704) | 1.89883113 |
91 | Abnormality of T cell physiology (HP:0011840) | 1.89240193 |
92 | Abnormality of the radial head (HP:0003995) | 1.88964686 |
93 | Stomatitis (HP:0010280) | 1.88770154 |
94 | Supernumerary bones of the axial skeleton (HP:0009144) | 1.88603182 |
95 | Absent frontal sinuses (HP:0002688) | 1.87742734 |
96 | Skin tags (HP:0010609) | 1.87619498 |
97 | Keratoconjunctivitis (HP:0001096) | 1.87590952 |
98 | Optic neuritis (HP:0100653) | 1.87443201 |
99 | Retrobulbar optic neuritis (HP:0100654) | 1.87443201 |
100 | Broad hallux (HP:0010055) | 1.87273478 |
101 | Abnormality of the pleura (HP:0002103) | 1.86708929 |
102 | Lip pit (HP:0100267) | 1.85446254 |
103 | Tubulointerstitial abnormality (HP:0001969) | 1.85344338 |
104 | Intestinal fistula (HP:0100819) | 1.85141016 |
105 | Medial flaring of the eyebrow (HP:0010747) | 1.84162018 |
106 | Short phalanx of the thumb (HP:0009660) | 1.83310491 |
107 | Hip dysplasia (HP:0001385) | 1.83097889 |
108 | Granulocytopenia (HP:0001913) | 1.82636453 |
109 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.82509824 |
110 | Pancreatic fibrosis (HP:0100732) | 1.82441696 |
111 | Vasculitis (HP:0002633) | 1.81174465 |
112 | Down-sloping shoulders (HP:0200021) | 1.80706917 |
113 | Hyperacusis (HP:0010780) | 1.80484796 |
114 | Broad toe (HP:0001837) | 1.80389392 |
115 | IgA deficiency (HP:0002720) | 1.79909232 |
116 | Abnormal hair whorl (HP:0010721) | 1.79435378 |
117 | Genetic anticipation (HP:0003743) | 1.78615821 |
118 | Hemiplegia (HP:0002301) | 1.78279039 |
119 | Abnormality of the intervertebral disk (HP:0005108) | 1.77707771 |
120 | Chest pain (HP:0100749) | 1.76873419 |
121 | Spondylolisthesis (HP:0003302) | 1.76856955 |
122 | True hermaphroditism (HP:0010459) | 1.76711160 |
123 | Orchitis (HP:0100796) | 1.75745456 |
124 | Long palpebral fissure (HP:0000637) | 1.74896613 |
125 | Gaze-evoked nystagmus (HP:0000640) | 1.74650422 |
126 | Keratoconjunctivitis sicca (HP:0001097) | 1.74423337 |
127 | Basal cell carcinoma (HP:0002671) | 1.74393582 |
128 | Toxemia of pregnancy (HP:0100603) | 1.74192326 |
129 | Dilatation of the ascending aorta (HP:0005111) | 1.73934350 |
130 | Anal stenosis (HP:0002025) | 1.73202799 |
131 | Abnormality of T cells (HP:0002843) | 1.72294551 |
132 | Eosinophilia (HP:0001880) | 1.72293749 |
133 | Hypoplasia of the thymus (HP:0000778) | 1.72084974 |
134 | Tubulointerstitial fibrosis (HP:0005576) | 1.71929867 |
135 | Increased number of teeth (HP:0011069) | 1.71641714 |
136 | Dislocated radial head (HP:0003083) | 1.71434668 |
137 | Acute myeloid leukemia (HP:0004808) | 1.71280692 |
138 | Progressive cerebellar ataxia (HP:0002073) | 1.71169839 |
139 | Agammaglobulinemia (HP:0004432) | 1.70878000 |
140 | Pulmonary infiltrates (HP:0002113) | 1.70816150 |
141 | Abnormality of the labia majora (HP:0012881) | 1.70582737 |
142 | Cone-shaped epiphyses of the phalanges of the hand (HP:0010230) | 1.69319377 |
143 | Severe combined immunodeficiency (HP:0004430) | 1.69024587 |
144 | Acute lymphatic leukemia (HP:0006721) | 1.68786340 |
145 | Follicular hyperkeratosis (HP:0007502) | 1.68388076 |
146 | Abnormality of the diencephalon (HP:0010662) | 1.67555321 |
147 | Milia (HP:0001056) | 1.66429474 |
148 | IgM deficiency (HP:0002850) | 1.66201482 |
149 | Absent speech (HP:0001344) | 1.66131532 |
150 | Leukocytosis (HP:0001974) | 1.66081932 |
151 | Arthropathy (HP:0003040) | 1.65107757 |
152 | Abnormality of dental color (HP:0011073) | 1.64617920 |
153 | Hypoplastic ischia (HP:0003175) | 1.64555699 |
154 | Aqueductal stenosis (HP:0002410) | 1.63991272 |
155 | Recurrent cutaneous fungal infections (HP:0011370) | 1.63006512 |
156 | Chronic mucocutaneous candidiasis (HP:0002728) | 1.63006512 |
157 | Broad thumb (HP:0011304) | 1.62752409 |
158 | Smooth philtrum (HP:0000319) | 1.61712516 |
159 | Aortic dissection (HP:0002647) | 1.61261140 |
160 | Bulbous nose (HP:0000414) | 1.60792124 |
161 | Mesomelia (HP:0003027) | 1.60784179 |
162 | Overgrowth (HP:0001548) | 1.60597542 |
163 | Deviation of the hallux (HP:0010051) | 1.60099889 |
164 | Albinism (HP:0001022) | 1.59959105 |
165 | Abnormality of the incisor (HP:0000676) | 1.59236668 |
166 | Spontaneous hematomas (HP:0007420) | 1.59102367 |
167 | Bronchiectasis (HP:0002110) | 1.57042283 |
168 | Tubulointerstitial nephritis (HP:0001970) | 1.56426194 |
169 | Abnormality of the ischium (HP:0003174) | 1.55816530 |
170 | Keratitis (HP:0000491) | 1.55784124 |
171 | Abnormality of the alveolar ridges (HP:0006477) | 1.55744430 |
Rank | Gene Set | Z-score |
---|---|---|
1 | CDK12 | 3.14961247 |
2 | FGFR4 | 3.12743284 |
3 | FGFR2 | 3.11346213 |
4 | MAP4K1 | 3.07717213 |
5 | FRK | 3.07068893 |
6 | JAK3 | 3.00905566 |
7 | FGFR3 | 2.56662521 |
8 | TYK2 | 2.43412684 |
9 | MAP3K10 | 2.42890066 |
10 | MAP3K14 | 2.39263084 |
11 | TXK | 2.30385576 |
12 | CHUK | 2.25602851 |
13 | JAK1 | 2.20342631 |
14 | EPHA3 | 2.19344046 |
15 | ITK | 2.14476555 |
16 | MAP4K2 | 2.13415276 |
17 | TRIB3 | 1.84855457 |
18 | ACVR1B | 1.78031345 |
19 | IKBKB | 1.77047856 |
20 | IKBKE | 1.74806346 |
21 | CAMK1G | 1.71102600 |
22 | ZAP70 | 1.70537892 |
23 | PDGFRA | 1.66090311 |
24 | PAK3 | 1.63899100 |
25 | AKT3 | 1.57506580 |
26 | SIK3 | 1.57278253 |
27 | ADRBK2 | 1.56391433 |
28 | MAP3K13 | 1.52670022 |
29 | FGFR1 | 1.50818624 |
30 | ERBB3 | 1.50508787 |
31 | MAPK13 | 1.50283030 |
32 | CAMK1D | 1.48446838 |
33 | TNIK | 1.44699405 |
34 | TBK1 | 1.42991130 |
35 | CASK | 1.40540034 |
36 | BRD4 | 1.38138870 |
37 | STK10 | 1.37618793 |
38 | CAMKK2 | 1.37431672 |
39 | DMPK | 1.37114485 |
40 | IRAK4 | 1.36138890 |
41 | PDGFRB | 1.34723981 |
42 | TYRO3 | 1.33108503 |
43 | SIK2 | 1.32411163 |
44 | GRK6 | 1.32064246 |
45 | BCR | 1.29828258 |
46 | EEF2K | 1.29023389 |
47 | KIT | 1.23361637 |
48 | SIK1 | 1.22217178 |
49 | HCK | 1.19704488 |
50 | PTK6 | 1.18285146 |
51 | WNK3 | 1.17886799 |
52 | RPS6KA4 | 1.16775826 |
53 | NLK | 1.12939094 |
54 | LCK | 1.11560290 |
55 | MAP3K4 | 1.10830697 |
56 | FES | 1.10250674 |
57 | PINK1 | 1.10162678 |
58 | GRK7 | 1.09639278 |
59 | TRPM7 | 1.09367732 |
60 | PIK3CA | 1.08499047 |
61 | LATS1 | 1.06223119 |
62 | SYK | 1.02480567 |
63 | MKNK2 | 1.02149222 |
64 | IRAK2 | 0.99803043 |
65 | TTN | 0.99450875 |
66 | PKN2 | 0.97036473 |
67 | TEC | 0.95758503 |
68 | MAP3K7 | 0.95001860 |
69 | TGFBR2 | 0.94631385 |
70 | BTK | 0.94179908 |
71 | MARK1 | 0.93652119 |
72 | BMPR1B | 0.93371698 |
73 | NUAK1 | 0.92025201 |
74 | CSK | 0.89103452 |
75 | SGK2 | 0.88245854 |
76 | KDR | 0.86021632 |
77 | PIK3CG | 0.85887885 |
78 | EPHB1 | 0.84756014 |
79 | LRRK2 | 0.84664425 |
80 | JAK2 | 0.84363982 |
81 | MTOR | 0.83982535 |
82 | IRAK1 | 0.82365624 |
83 | CSF1R | 0.81876829 |
84 | CDK6 | 0.81782347 |
85 | BLK | 0.80868508 |
86 | STK3 | 0.77930581 |
87 | STK24 | 0.77500592 |
88 | RET | 0.77241932 |
89 | CDK9 | 0.76906259 |
90 | PIM1 | 0.76891328 |
91 | ERN1 | 0.73437198 |
92 | DYRK1A | 0.73343683 |
93 | INSRR | 0.71000259 |
94 | PRKD2 | 0.68703537 |
95 | FLT3 | 0.67934477 |
96 | TNK2 | 0.66239095 |
97 | PRKCH | 0.65865394 |
98 | ICK | 0.65753509 |
99 | HIPK2 | 0.65366247 |
100 | MARK2 | 0.64856393 |
101 | GRK1 | 0.63255064 |
102 | EPHB2 | 0.62310941 |
103 | CDK4 | 0.60482994 |
104 | SGK3 | 0.60089405 |
105 | RIPK1 | 0.60025279 |
106 | PRKCE | 0.58568093 |
107 | NEK9 | 0.58335283 |
108 | BMX | 0.54247616 |
109 | EGFR | 0.53914855 |
110 | MATK | 0.53251149 |
111 | WNK1 | 0.53130924 |
112 | NEK2 | 0.51206541 |
113 | STK38 | 0.50838768 |
114 | CDK3 | 0.50612543 |
115 | STK38L | 0.49453266 |
116 | TGFBR1 | 0.48483595 |
117 | MAPK7 | 0.48271482 |
118 | PRKAA2 | 0.48118257 |
119 | MARK3 | 0.47986881 |
120 | PASK | 0.47850205 |
121 | CDC42BPA | 0.47060792 |
122 | MST4 | 0.46968470 |
123 | PRKD1 | 0.46804043 |
124 | OBSCN | 0.46130787 |
125 | KSR1 | 0.46130448 |
126 | IGF1R | 0.45816396 |
127 | NTRK2 | 0.45139178 |
128 | PTK2 | 0.44578323 |
129 | DYRK1B | 0.44018670 |
130 | ALK | 0.43219620 |
131 | INSR | 0.42668427 |
132 | TAOK3 | 0.41396562 |
133 | CAMK4 | 0.41284572 |
134 | EPHA4 | 0.41262479 |
135 | TAOK1 | 0.40485826 |
136 | STK39 | 0.40481075 |
137 | EIF2AK3 | 0.39488349 |
138 | MELK | 0.39382693 |
139 | RPS6KA1 | 0.39212630 |
140 | * PRKCQ | 0.38118784 |
141 | ATR | 0.37484764 |
142 | LYN | 0.37147286 |
143 | CLK1 | 0.36840222 |
144 | MAPKAPK2 | 0.36469370 |
145 | DDR2 | 0.36198683 |
146 | STK4 | 0.35759031 |
Rank | Gene Set | Z-score |
---|---|---|
1 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.39622772 |
2 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.30277030 |
3 | * T cell receptor signaling pathway_Homo sapiens_hsa04660 | 2.23910092 |
4 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.89596964 |
5 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.88578687 |
6 | Leishmaniasis_Homo sapiens_hsa05140 | 1.87199904 |
7 | * Measles_Homo sapiens_hsa05162 | 1.86473551 |
8 | Viral myocarditis_Homo sapiens_hsa05416 | 1.78356466 |
9 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.78000693 |
10 | Allograft rejection_Homo sapiens_hsa05330 | 1.72552644 |
11 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.69171374 |
12 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.67749850 |
13 | * Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.59154732 |
14 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.58898950 |
15 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.55731154 |
16 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.53726823 |
17 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.52948626 |
18 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.51997065 |
19 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.50321364 |
20 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.47740247 |
21 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.44452914 |
22 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.42578943 |
23 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.42437261 |
24 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.42139039 |
25 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.41364570 |
26 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.40716741 |
27 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.36778043 |
28 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.35614135 |
29 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.33602238 |
30 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.32055378 |
31 | Hepatitis B_Homo sapiens_hsa05161 | 1.30842135 |
32 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.30685832 |
33 | Circadian rhythm_Homo sapiens_hsa04710 | 1.27289234 |
34 | Shigellosis_Homo sapiens_hsa05131 | 1.26626993 |
35 | Apoptosis_Homo sapiens_hsa04210 | 1.25998435 |
36 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.25673005 |
37 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.24830568 |
38 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.24743628 |
39 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.24575042 |
40 | Colorectal cancer_Homo sapiens_hsa05210 | 1.24353792 |
41 | HTLV-I infection_Homo sapiens_hsa05166 | 1.23580480 |
42 | Influenza A_Homo sapiens_hsa05164 | 1.19040004 |
43 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.18726735 |
44 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 1.17127926 |
45 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.13846887 |
46 | * Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.11334909 |
47 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.11283270 |
48 | * Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.09002338 |
49 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.08089578 |
50 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.05729038 |
51 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.05505998 |
52 | Adherens junction_Homo sapiens_hsa04520 | 1.04512355 |
53 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 1.03742578 |
54 | Prostate cancer_Homo sapiens_hsa05215 | 1.02691150 |
55 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.99648876 |
56 | Endometrial cancer_Homo sapiens_hsa05213 | 0.97870013 |
57 | Tuberculosis_Homo sapiens_hsa05152 | 0.97023914 |
58 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.96490866 |
59 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.96443145 |
60 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.95509209 |
61 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.94656846 |
62 | * Pathways in cancer_Homo sapiens_hsa05200 | 0.94200927 |
63 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.93777349 |
64 | Lysine degradation_Homo sapiens_hsa00310 | 0.93315435 |
65 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.91451423 |
66 | Phototransduction_Homo sapiens_hsa04744 | 0.89357589 |
67 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.89308223 |
68 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.86591559 |
69 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.85381566 |
70 | Platelet activation_Homo sapiens_hsa04611 | 0.83787413 |
71 | Malaria_Homo sapiens_hsa05144 | 0.83542183 |
72 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.82451997 |
73 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.82247189 |
74 | Focal adhesion_Homo sapiens_hsa04510 | 0.81693652 |
75 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.81171513 |
76 | Hepatitis C_Homo sapiens_hsa05160 | 0.80676176 |
77 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.80042894 |
78 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.79423615 |
79 | Glioma_Homo sapiens_hsa05214 | 0.79043524 |
80 | Insulin resistance_Homo sapiens_hsa04931 | 0.77606282 |
81 | ABC transporters_Homo sapiens_hsa02010 | 0.77579897 |
82 | Pertussis_Homo sapiens_hsa05133 | 0.75524760 |
83 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.74495795 |
84 | Protein export_Homo sapiens_hsa03060 | 0.72123298 |
85 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.71982573 |
86 | Legionellosis_Homo sapiens_hsa05134 | 0.71231925 |
87 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.71175623 |
88 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.71068302 |
89 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.70838536 |
90 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.70704987 |
91 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.68324938 |
92 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.67856714 |
93 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.67563900 |
94 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.65632372 |
95 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.65579079 |
96 | Axon guidance_Homo sapiens_hsa04360 | 0.65224111 |
97 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.64507165 |
98 | Asthma_Homo sapiens_hsa05310 | 0.64465239 |
99 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.64238299 |
100 | Salmonella infection_Homo sapiens_hsa05132 | 0.64061339 |
101 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.63358478 |
102 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.63106414 |
103 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.62780592 |
104 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.62675024 |
105 | Amoebiasis_Homo sapiens_hsa05146 | 0.62158681 |
106 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.61420430 |
107 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.61049667 |
108 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.60995156 |
109 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.60631131 |
110 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.59743380 |
111 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.59246527 |
112 | Basal transcription factors_Homo sapiens_hsa03022 | 0.56931214 |
113 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.56890115 |
114 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.56672755 |
115 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.55714078 |
116 | * Endocytosis_Homo sapiens_hsa04144 | 0.54146817 |
117 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.53146422 |
118 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.52739660 |
119 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.52580400 |
120 | Taste transduction_Homo sapiens_hsa04742 | 0.52068872 |
121 | Melanoma_Homo sapiens_hsa05218 | 0.51872076 |
122 | * ErbB signaling pathway_Homo sapiens_hsa04012 | 0.51866739 |
123 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.51069319 |
124 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.50842725 |
125 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.50618063 |
126 | Mineral absorption_Homo sapiens_hsa04978 | 0.49816981 |
127 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.45523588 |
128 | Renin secretion_Homo sapiens_hsa04924 | 0.41778170 |
129 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.37344529 |
130 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.34962556 |
131 | Olfactory transduction_Homo sapiens_hsa04740 | 0.34775245 |
132 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.33018744 |
133 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.32940083 |