

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 6.80860396 |
| 2 | thalamus development (GO:0021794) | 6.13881398 |
| 3 | negative regulation of cAMP-mediated signaling (GO:0043951) | 5.74800471 |
| 4 | positive regulation of cAMP-mediated signaling (GO:0043950) | 5.54422048 |
| 5 | negative regulation of calcium ion-dependent exocytosis (GO:0045955) | 5.41147776 |
| 6 | behavioral response to ethanol (GO:0048149) | 5.35625560 |
| 7 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 5.34755931 |
| 8 | meiotic chromosome segregation (GO:0045132) | 5.27427168 |
| 9 | opioid receptor signaling pathway (GO:0038003) | 5.24619040 |
| 10 | response to xenobiotic stimulus (GO:0009410) | 4.90032200 |
| 11 | regulation of ER to Golgi vesicle-mediated transport (GO:0060628) | 4.69503582 |
| 12 | retinal cone cell development (GO:0046549) | 4.68683301 |
| 13 | kinetochore organization (GO:0051383) | 4.60161496 |
| 14 | sphingosine metabolic process (GO:0006670) | 4.55676290 |
| 15 | adult feeding behavior (GO:0008343) | 4.45547867 |
| 16 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc | 4.44645401 |
| 17 | regulation of protein glycosylation (GO:0060049) | 4.34684601 |
| 18 | regulation of meiosis I (GO:0060631) | 4.24551220 |
| 19 | cell proliferation in forebrain (GO:0021846) | 4.10039645 |
| 20 | sphingoid metabolic process (GO:0046519) | 4.03876687 |
| 21 | snRNA transcription (GO:0009301) | 4.03814264 |
| 22 | ether lipid metabolic process (GO:0046485) | 4.02312183 |
| 23 | fucose catabolic process (GO:0019317) | 4.02041337 |
| 24 | L-fucose metabolic process (GO:0042354) | 4.02041337 |
| 25 | L-fucose catabolic process (GO:0042355) | 4.02041337 |
| 26 | diol metabolic process (GO:0034311) | 3.96898590 |
| 27 | transmission of nerve impulse (GO:0019226) | 3.96673165 |
| 28 | cellular biogenic amine catabolic process (GO:0042402) | 3.94603015 |
| 29 | amine catabolic process (GO:0009310) | 3.94603015 |
| 30 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 3.94257707 |
| 31 | regulation of glutamate receptor signaling pathway (GO:1900449) | 3.91691104 |
| 32 | notochord development (GO:0030903) | 3.89976584 |
| 33 | intra-S DNA damage checkpoint (GO:0031573) | 3.88220944 |
| 34 | positive regulation of histone deacetylation (GO:0031065) | 3.84520341 |
| 35 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 3.78686120 |
| 36 | piRNA metabolic process (GO:0034587) | 3.75262717 |
| 37 | regulation of glucokinase activity (GO:0033131) | 3.71896477 |
| 38 | regulation of hexokinase activity (GO:1903299) | 3.71896477 |
| 39 | cysteine metabolic process (GO:0006534) | 3.68600809 |
| 40 | positive regulation of neuroblast proliferation (GO:0002052) | 3.68119685 |
| 41 | regulation of hippo signaling (GO:0035330) | 3.67414194 |
| 42 | regulation of acrosome reaction (GO:0060046) | 3.60820673 |
| 43 | regulation of cAMP-mediated signaling (GO:0043949) | 3.55922313 |
| 44 | regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095) | 3.54795712 |
| 45 | replication fork processing (GO:0031297) | 3.53214671 |
| 46 | urate metabolic process (GO:0046415) | 3.47567159 |
| 47 | histone H3-K9 modification (GO:0061647) | 3.46193963 |
| 48 | negative regulation of astrocyte differentiation (GO:0048712) | 3.45163860 |
| 49 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.43323995 |
| 50 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.43323995 |
| 51 | N-terminal protein amino acid acetylation (GO:0006474) | 3.37645567 |
| 52 | polyamine biosynthetic process (GO:0006596) | 3.31247336 |
| 53 | behavioral response to nicotine (GO:0035095) | 3.29984635 |
| 54 | thrombin receptor signaling pathway (GO:0070493) | 3.27858981 |
| 55 | cellular biogenic amine biosynthetic process (GO:0042401) | 3.26852190 |
| 56 | cornea development in camera-type eye (GO:0061303) | 3.19005872 |
| 57 | epithelial cilium movement (GO:0003351) | 3.17090302 |
| 58 | regulation of translational termination (GO:0006449) | 3.09997556 |
| 59 | amine biosynthetic process (GO:0009309) | 3.04982056 |
| 60 | regulation of neuroblast proliferation (GO:1902692) | 3.02734999 |
| 61 | regulation of odontogenesis of dentin-containing tooth (GO:0042487) | 2.97324303 |
| 62 | white fat cell differentiation (GO:0050872) | 2.96285953 |
| 63 | regulation of thymocyte apoptotic process (GO:0070243) | 2.94501308 |
| 64 | regulation of non-canonical Wnt signaling pathway (GO:2000050) | 2.92407716 |
| 65 | arginine catabolic process (GO:0006527) | 2.88879584 |
| 66 | superoxide anion generation (GO:0042554) | 2.82234881 |
| 67 | heart valve formation (GO:0003188) | 2.77741235 |
| 68 | L-ascorbic acid metabolic process (GO:0019852) | 2.77010966 |
| 69 | protein import into peroxisome matrix (GO:0016558) | 2.76909183 |
| 70 | forebrain neuron differentiation (GO:0021879) | 2.75905810 |
| 71 | negative regulation of thymocyte apoptotic process (GO:0070244) | 2.73017902 |
| 72 | synaptic transmission, glutamatergic (GO:0035249) | 2.71980932 |
| 73 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 2.71635974 |
| 74 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.70269132 |
| 75 | negative regulation by host of viral transcription (GO:0043922) | 2.69994799 |
| 76 | axoneme assembly (GO:0035082) | 2.69856345 |
| 77 | cAMP catabolic process (GO:0006198) | 2.69827009 |
| 78 | regulation of posttranscriptional gene silencing (GO:0060147) | 2.67412426 |
| 79 | regulation of gene silencing by miRNA (GO:0060964) | 2.67412426 |
| 80 | regulation of gene silencing by RNA (GO:0060966) | 2.67412426 |
| 81 | photoreceptor cell maintenance (GO:0045494) | 2.67328442 |
| 82 | cellular response to alkaloid (GO:0071312) | 2.66792035 |
| 83 | double-strand break repair via homologous recombination (GO:0000724) | 2.65840158 |
| 84 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.65490726 |
| 85 | smooth muscle tissue development (GO:0048745) | 2.65395418 |
| 86 | cardiolipin metabolic process (GO:0032048) | 2.64498682 |
| 87 | recombinational repair (GO:0000725) | 2.63906609 |
| 88 | glycerol metabolic process (GO:0006071) | 2.63091333 |
| 89 | positive regulation of neural precursor cell proliferation (GO:2000179) | 2.62917375 |
| 90 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 2.59991163 |
| 91 | regulation of synapse maturation (GO:0090128) | 2.59800600 |
| 92 | cellular response to sterol (GO:0036315) | 2.57888882 |
| 93 | negative regulation of histone acetylation (GO:0035067) | 2.57460823 |
| 94 | negative regulation of adenylate cyclase activity (GO:0007194) | 2.57402750 |
| 95 | positive regulation of protein deacetylation (GO:0090312) | 2.56496548 |
| 96 | regulation of timing of cell differentiation (GO:0048505) | 2.56091681 |
| 97 | inner ear receptor stereocilium organization (GO:0060122) | 2.55692972 |
| 98 | negative regulation of nitric oxide biosynthetic process (GO:0045019) | 2.55118675 |
| 99 | resolution of meiotic recombination intermediates (GO:0000712) | 2.53628922 |
| 100 | centriole replication (GO:0007099) | 2.53084275 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.49913783 |
| 2 | VDR_22108803_ChIP-Seq_LS180_Human | 3.16203401 |
| 3 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.98674267 |
| 4 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 2.98674267 |
| 5 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.55054722 |
| 6 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.47732320 |
| 7 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.46412574 |
| 8 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.44999001 |
| 9 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.43537571 |
| 10 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.38301436 |
| 11 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.36649756 |
| 12 | IRF1_19129219_ChIP-ChIP_H3396_Human | 2.33720986 |
| 13 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.26724321 |
| 14 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.18199849 |
| 15 | P300_19829295_ChIP-Seq_ESCs_Human | 2.00011659 |
| 16 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.85897408 |
| 17 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.84131771 |
| 18 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.81897098 |
| 19 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.79162456 |
| 20 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.76174891 |
| 21 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.63629361 |
| 22 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.62266339 |
| 23 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.60742620 |
| 24 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.58744242 |
| 25 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.58309241 |
| 26 | TCF4_23295773_ChIP-Seq_U87_Human | 1.57681912 |
| 27 | RXR_22108803_ChIP-Seq_LS180_Human | 1.55518806 |
| 28 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.53382686 |
| 29 | STAT3_23295773_ChIP-Seq_U87_Human | 1.52170381 |
| 30 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.50851967 |
| 31 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.49977239 |
| 32 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.48793112 |
| 33 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.47698793 |
| 34 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.47263883 |
| 35 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.46976338 |
| 36 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.46213153 |
| 37 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.44749609 |
| 38 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.41697719 |
| 39 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.41685155 |
| 40 | FUS_26573619_Chip-Seq_HEK293_Human | 1.40010711 |
| 41 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.39460123 |
| 42 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.38846310 |
| 43 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.38624820 |
| 44 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.38452723 |
| 45 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.35478160 |
| 46 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.34763368 |
| 47 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.33269732 |
| 48 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.32608700 |
| 49 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.31386280 |
| 50 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.31313698 |
| 51 | EWS_26573619_Chip-Seq_HEK293_Human | 1.30378586 |
| 52 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.29369806 |
| 53 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.29369806 |
| 54 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.28530473 |
| 55 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.27984348 |
| 56 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.26883646 |
| 57 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.26611632 |
| 58 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.26574621 |
| 59 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.24419170 |
| 60 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.22977783 |
| 61 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.22450099 |
| 62 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.21827768 |
| 63 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.20991332 |
| 64 | AR_25329375_ChIP-Seq_VCAP_Human | 1.20644494 |
| 65 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.20565172 |
| 66 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.20522805 |
| 67 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.19079848 |
| 68 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.17523212 |
| 69 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 1.16294414 |
| 70 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.15931904 |
| 71 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.15066797 |
| 72 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.14650904 |
| 73 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.14098544 |
| 74 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.13116986 |
| 75 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.12375937 |
| 76 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.11235864 |
| 77 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.09920778 |
| 78 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.09427137 |
| 79 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.07769112 |
| 80 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.07628830 |
| 81 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.06210853 |
| 82 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.06154025 |
| 83 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.06080633 |
| 84 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.06007834 |
| 85 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.05837960 |
| 86 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.05837960 |
| 87 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.05741425 |
| 88 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.04983443 |
| 89 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.04930859 |
| 90 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 1.04345779 |
| 91 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.03366113 |
| 92 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.03036052 |
| 93 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.02852305 |
| 94 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.02828560 |
| 95 | OCT1_27270436_Chip-Seq_PROSTATE_Human | 1.02568113 |
| 96 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.00930887 |
| 97 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.00683655 |
| 98 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.00129632 |
| 99 | JUN_21703547_ChIP-Seq_K562_Human | 0.99721898 |
| 100 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.99035509 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003136_yellow_coat_color | 4.31938995 |
| 2 | MP0005085_abnormal_gallbladder_physiolo | 3.67139739 |
| 3 | MP0001968_abnormal_touch/_nociception | 3.36771735 |
| 4 | MP0002653_abnormal_ependyma_morphology | 3.18582004 |
| 5 | MP0002138_abnormal_hepatobiliary_system | 3.16093552 |
| 6 | MP0003890_abnormal_embryonic-extraembry | 3.05491126 |
| 7 | MP0003646_muscle_fatigue | 2.86860279 |
| 8 | MP0002876_abnormal_thyroid_physiology | 2.80742016 |
| 9 | MP0008057_abnormal_DNA_replication | 2.78195349 |
| 10 | MP0006292_abnormal_olfactory_placode | 2.44317021 |
| 11 | MP0005083_abnormal_biliary_tract | 2.42202417 |
| 12 | MP0002837_dystrophic_cardiac_calcinosis | 2.33836306 |
| 13 | MP0003252_abnormal_bile_duct | 2.33331472 |
| 14 | MP0005365_abnormal_bile_salt | 2.21536218 |
| 15 | MP0009278_abnormal_bone_marrow | 2.06150869 |
| 16 | MP0001486_abnormal_startle_reflex | 2.01603891 |
| 17 | MP0008872_abnormal_physiological_respon | 1.97386357 |
| 18 | MP0009764_decreased_sensitivity_to | 1.96435183 |
| 19 | MP0005645_abnormal_hypothalamus_physiol | 1.93742409 |
| 20 | MP0002736_abnormal_nociception_after | 1.91953898 |
| 21 | MP0003879_abnormal_hair_cell | 1.91519055 |
| 22 | MP0008877_abnormal_DNA_methylation | 1.88676692 |
| 23 | MP0003718_maternal_effect | 1.79512735 |
| 24 | MP0001501_abnormal_sleep_pattern | 1.79276436 |
| 25 | MP0005551_abnormal_eye_electrophysiolog | 1.79054395 |
| 26 | MP0002733_abnormal_thermal_nociception | 1.75215432 |
| 27 | MP0004142_abnormal_muscle_tone | 1.74761147 |
| 28 | MP0003045_fibrosis | 1.74043384 |
| 29 | MP0008004_abnormal_stomach_pH | 1.71029807 |
| 30 | MP0001664_abnormal_digestion | 1.64480068 |
| 31 | MP0005646_abnormal_pituitary_gland | 1.59832948 |
| 32 | MP0005360_urolithiasis | 1.57019320 |
| 33 | MP0008875_abnormal_xenobiotic_pharmacok | 1.56180427 |
| 34 | MP0002272_abnormal_nervous_system | 1.51976750 |
| 35 | MP0009745_abnormal_behavioral_response | 1.50076151 |
| 36 | MP0004145_abnormal_muscle_electrophysio | 1.46295767 |
| 37 | MP0003633_abnormal_nervous_system | 1.44587152 |
| 38 | MP0005423_abnormal_somatic_nervous | 1.36945381 |
| 39 | MP0001970_abnormal_pain_threshold | 1.36776374 |
| 40 | MP0009697_abnormal_copulation | 1.35021685 |
| 41 | MP0003937_abnormal_limbs/digits/tail_de | 1.33253222 |
| 42 | MP0003787_abnormal_imprinting | 1.31126943 |
| 43 | MP0003880_abnormal_central_pattern | 1.30510925 |
| 44 | MP0002163_abnormal_gland_morphology | 1.28973191 |
| 45 | MP0002557_abnormal_social/conspecific_i | 1.28152368 |
| 46 | MP0009053_abnormal_anal_canal | 1.27462875 |
| 47 | MP0001440_abnormal_grooming_behavior | 1.27067549 |
| 48 | MP0001529_abnormal_vocalization | 1.23524376 |
| 49 | MP0002822_catalepsy | 1.22178446 |
| 50 | MP0000678_abnormal_parathyroid_gland | 1.20183389 |
| 51 | MP0002572_abnormal_emotion/affect_behav | 1.15998769 |
| 52 | MP0005464_abnormal_platelet_physiology | 1.14869357 |
| 53 | MP0000778_abnormal_nervous_system | 1.13892098 |
| 54 | MP0000383_abnormal_hair_follicle | 1.13769322 |
| 55 | MP0005670_abnormal_white_adipose | 1.12573077 |
| 56 | MP0002249_abnormal_larynx_morphology | 1.11653209 |
| 57 | MP0008569_lethality_at_weaning | 1.06651509 |
| 58 | MP0003959_abnormal_lean_body | 1.06585078 |
| 59 | MP0002067_abnormal_sensory_capabilities | 1.05296757 |
| 60 | MP0000049_abnormal_middle_ear | 1.00411651 |
| 61 | MP0006072_abnormal_retinal_apoptosis | 1.00073635 |
| 62 | MP0000230_abnormal_systemic_arterial | 0.95273804 |
| 63 | MP0004924_abnormal_behavior | 0.94371338 |
| 64 | MP0005386_behavior/neurological_phenoty | 0.94371338 |
| 65 | MP0004147_increased_porphyrin_level | 0.93573924 |
| 66 | MP0001545_abnormal_hematopoietic_system | 0.92102028 |
| 67 | MP0005397_hematopoietic_system_phenotyp | 0.92102028 |
| 68 | MP0002752_abnormal_somatic_nervous | 0.91390306 |
| 69 | MP0002063_abnormal_learning/memory/cond | 0.90955105 |
| 70 | MP0002064_seizures | 0.90441174 |
| 71 | MP0002184_abnormal_innervation | 0.90286247 |
| 72 | MP0005409_darkened_coat_color | 0.89890461 |
| 73 | MP0003195_calcinosis | 0.86782970 |
| 74 | MP0009780_abnormal_chondrocyte_physiolo | 0.86340935 |
| 75 | MP0005503_abnormal_tendon_morphology | 0.83722683 |
| 76 | MP0004742_abnormal_vestibular_system | 0.83180318 |
| 77 | MP0008058_abnormal_DNA_repair | 0.82909859 |
| 78 | MP0004043_abnormal_pH_regulation | 0.82900453 |
| 79 | MP0003631_nervous_system_phenotype | 0.80027069 |
| 80 | MP0003638_abnormal_response/metabolism_ | 0.79935240 |
| 81 | MP0003635_abnormal_synaptic_transmissio | 0.79318110 |
| 82 | MP0000026_abnormal_inner_ear | 0.78467467 |
| 83 | MP0009046_muscle_twitch | 0.77226227 |
| 84 | MP0005195_abnormal_posterior_eye | 0.76855487 |
| 85 | MP0002229_neurodegeneration | 0.76444170 |
| 86 | MP0001963_abnormal_hearing_physiology | 0.74830745 |
| 87 | MP0000015_abnormal_ear_pigmentation | 0.74524117 |
| 88 | MP0000955_abnormal_spinal_cord | 0.74245719 |
| 89 | MP0003567_abnormal_fetal_cardiomyocyte | 0.73702483 |
| 90 | MP0000428_abnormal_craniofacial_morphol | 0.70969282 |
| 91 | MP0000427_abnormal_hair_cycle | 0.70793139 |
| 92 | MP0003122_maternal_imprinting | 0.70203431 |
| 93 | MP0004085_abnormal_heartbeat | 0.69108765 |
| 94 | MP0003698_abnormal_male_reproductive | 0.67572501 |
| 95 | MP0003938_abnormal_ear_development | 0.67212801 |
| 96 | MP0000631_abnormal_neuroendocrine_gland | 0.66632217 |
| 97 | MP0002090_abnormal_vision | 0.66318227 |
| 98 | MP0006035_abnormal_mitochondrial_morpho | 0.66169766 |
| 99 | MP0005395_other_phenotype | 0.65450193 |
| 100 | MP0005377_hearing/vestibular/ear_phenot | 0.64451225 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Thyroid-stimulating hormone excess (HP:0002925) | 5.78901550 |
| 2 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 5.67448687 |
| 3 | Intestinal atresia (HP:0011100) | 4.80615599 |
| 4 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 4.37643726 |
| 5 | Optic nerve hypoplasia (HP:0000609) | 4.36076820 |
| 6 | Abnormal rod and cone electroretinograms (HP:0008323) | 4.35163327 |
| 7 | Volvulus (HP:0002580) | 4.29884667 |
| 8 | Tubular atrophy (HP:0000092) | 4.09203649 |
| 9 | Pancreatic islet-cell hyperplasia (HP:0004510) | 4.02274430 |
| 10 | Asplenia (HP:0001746) | 3.90264182 |
| 11 | Abnormality of the aortic arch (HP:0012303) | 3.78301881 |
| 12 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 3.67963110 |
| 13 | Focal motor seizures (HP:0011153) | 3.65955899 |
| 14 | Abnormality of the labia minora (HP:0012880) | 3.56476575 |
| 15 | Pancreatic cysts (HP:0001737) | 3.54519484 |
| 16 | Type II lissencephaly (HP:0007260) | 3.43217124 |
| 17 | Broad alveolar ridges (HP:0000187) | 3.25396519 |
| 18 | Abnormality of the ileum (HP:0001549) | 3.21173087 |
| 19 | Tented upper lip vermilion (HP:0010804) | 3.17049417 |
| 20 | Conjugated hyperbilirubinemia (HP:0002908) | 3.07400317 |
| 21 | Agitation (HP:0000713) | 3.06359338 |
| 22 | Abnormality of the renal cortex (HP:0011035) | 3.06161365 |
| 23 | Large for gestational age (HP:0001520) | 3.05931698 |
| 24 | Colon cancer (HP:0003003) | 3.00520966 |
| 25 | Attenuation of retinal blood vessels (HP:0007843) | 2.99725394 |
| 26 | Increased density of long bones (HP:0006392) | 2.98868342 |
| 27 | Pendular nystagmus (HP:0012043) | 2.84575110 |
| 28 | Pancreatic fibrosis (HP:0100732) | 2.82227917 |
| 29 | Nephronophthisis (HP:0000090) | 2.69663731 |
| 30 | Molar tooth sign on MRI (HP:0002419) | 2.68634404 |
| 31 | Abnormality of midbrain morphology (HP:0002418) | 2.68634404 |
| 32 | Gastrointestinal atresia (HP:0002589) | 2.66797738 |
| 33 | Abnormality of the renal medulla (HP:0100957) | 2.66731657 |
| 34 | Polydipsia (HP:0001959) | 2.61737479 |
| 35 | Abnormal drinking behavior (HP:0030082) | 2.61737479 |
| 36 | Abnormality of macular pigmentation (HP:0008002) | 2.54152145 |
| 37 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.50859742 |
| 38 | Oligodontia (HP:0000677) | 2.42925049 |
| 39 | Aplasia/Hypoplasia affecting the fundus (HP:0008057) | 2.39973166 |
| 40 | Petechiae (HP:0000967) | 2.36156789 |
| 41 | Supernumerary spleens (HP:0009799) | 2.33659922 |
| 42 | Abnormal biliary tract physiology (HP:0012439) | 2.24961585 |
| 43 | Bile duct proliferation (HP:0001408) | 2.24961585 |
| 44 | Tubulointerstitial fibrosis (HP:0005576) | 2.21467585 |
| 45 | Bony spicule pigmentary retinopathy (HP:0007737) | 2.19748155 |
| 46 | Potter facies (HP:0002009) | 2.17264292 |
| 47 | Facial shape deformation (HP:0011334) | 2.17264292 |
| 48 | Retinal dysplasia (HP:0007973) | 2.15376816 |
| 49 | Fair hair (HP:0002286) | 2.14712727 |
| 50 | Cerebellar dysplasia (HP:0007033) | 2.14312566 |
| 51 | Pigmentary retinal degeneration (HP:0001146) | 2.14219389 |
| 52 | Gaze-evoked nystagmus (HP:0000640) | 2.13618130 |
| 53 | Hyperventilation (HP:0002883) | 2.12760169 |
| 54 | Hyperthyroidism (HP:0000836) | 2.10867693 |
| 55 | Abnormality of endocrine pancreas physiology (HP:0012093) | 2.09899164 |
| 56 | Abnormality of the pancreatic islet cells (HP:0006476) | 2.09899164 |
| 57 | Thickened helices (HP:0000391) | 2.09729962 |
| 58 | True hermaphroditism (HP:0010459) | 2.08459480 |
| 59 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.08115347 |
| 60 | Focal seizures (HP:0007359) | 2.08010011 |
| 61 | Dyschromatopsia (HP:0007641) | 2.07510920 |
| 62 | Chronic hepatic failure (HP:0100626) | 2.04701226 |
| 63 | Enlarged kidneys (HP:0000105) | 2.04548806 |
| 64 | Decreased central vision (HP:0007663) | 2.02072010 |
| 65 | Decreased muscle mass (HP:0003199) | 2.01557857 |
| 66 | Cystic liver disease (HP:0006706) | 2.00355912 |
| 67 | Severe visual impairment (HP:0001141) | 1.96058929 |
| 68 | Febrile seizures (HP:0002373) | 1.95912957 |
| 69 | Short 1st metacarpal (HP:0010034) | 1.95404751 |
| 70 | Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026) | 1.95404751 |
| 71 | Vitreoretinal degeneration (HP:0000655) | 1.94769475 |
| 72 | Meckel diverticulum (HP:0002245) | 1.94579719 |
| 73 | Embryonal renal neoplasm (HP:0011794) | 1.94437516 |
| 74 | Increased corneal curvature (HP:0100692) | 1.93935180 |
| 75 | Keratoconus (HP:0000563) | 1.93935180 |
| 76 | Congenital stationary night blindness (HP:0007642) | 1.93416074 |
| 77 | Duodenal stenosis (HP:0100867) | 1.91794556 |
| 78 | Small intestinal stenosis (HP:0012848) | 1.91794556 |
| 79 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 1.91588869 |
| 80 | Short 4th metacarpal (HP:0010044) | 1.91588869 |
| 81 | Chromsome breakage (HP:0040012) | 1.89433498 |
| 82 | Hypophosphatemic rickets (HP:0004912) | 1.88765083 |
| 83 | J-shaped sella turcica (HP:0002680) | 1.88552664 |
| 84 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.86197674 |
| 85 | Dandy-Walker malformation (HP:0001305) | 1.82635813 |
| 86 | Lissencephaly (HP:0001339) | 1.81268533 |
| 87 | Gingival bleeding (HP:0000225) | 1.79213711 |
| 88 | Hematochezia (HP:0002573) | 1.78629058 |
| 89 | Polyuria (HP:0000103) | 1.78438718 |
| 90 | Rib fusion (HP:0000902) | 1.76929681 |
| 91 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.76440310 |
| 92 | Abnormality of the carotid arteries (HP:0005344) | 1.75937344 |
| 93 | Abnormality of the duodenum (HP:0002246) | 1.74722868 |
| 94 | Central scotoma (HP:0000603) | 1.74086785 |
| 95 | Increased mean platelet volume (HP:0011877) | 1.69854070 |
| 96 | Decreased number of large peripheral myelinated nerve fibers (HP:0003387) | 1.69548712 |
| 97 | Abnormality of the 1st metacarpal (HP:0010009) | 1.69126177 |
| 98 | Amelogenesis imperfecta (HP:0000705) | 1.66055468 |
| 99 | Hypoplastic labia majora (HP:0000059) | 1.65773338 |
| 100 | Poor head control (HP:0002421) | 1.64536562 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ADRBK2 | 5.02462703 |
| 2 | CCNB1 | 4.72753781 |
| 3 | PKN2 | 4.12379232 |
| 4 | FRK | 3.96476733 |
| 5 | FLT3 | 3.21393097 |
| 6 | ARAF | 3.13541576 |
| 7 | MAP3K10 | 3.05252804 |
| 8 | ACVR1B | 2.54497561 |
| 9 | LATS1 | 2.40926920 |
| 10 | PIM2 | 2.31418619 |
| 11 | HIPK2 | 2.12592044 |
| 12 | PINK1 | 2.06273492 |
| 13 | BMPR1B | 2.04323701 |
| 14 | BRAF | 1.96499639 |
| 15 | NUAK1 | 1.88819948 |
| 16 | GRK1 | 1.79686469 |
| 17 | ZAK | 1.69586051 |
| 18 | ADRBK1 | 1.59907794 |
| 19 | PNCK | 1.58937502 |
| 20 | WNK4 | 1.56482944 |
| 21 | STK38L | 1.51387967 |
| 22 | DYRK2 | 1.51369285 |
| 23 | STK16 | 1.51165862 |
| 24 | PRKCI | 1.47011794 |
| 25 | TGFBR1 | 1.43279245 |
| 26 | TEC | 1.36638787 |
| 27 | LMTK2 | 1.34345518 |
| 28 | RAF1 | 1.28603884 |
| 29 | MELK | 1.21818878 |
| 30 | PRKCE | 1.18562628 |
| 31 | TAOK3 | 1.18170224 |
| 32 | PRKCG | 1.17558351 |
| 33 | EIF2AK1 | 1.08758840 |
| 34 | GRK5 | 1.03920202 |
| 35 | PTK2B | 0.98191322 |
| 36 | PAK3 | 0.96078862 |
| 37 | PLK2 | 0.95352387 |
| 38 | BMX | 0.94684233 |
| 39 | WEE1 | 0.92138120 |
| 40 | LATS2 | 0.85247332 |
| 41 | STK3 | 0.84517608 |
| 42 | TIE1 | 0.78328840 |
| 43 | PHKG1 | 0.77239547 |
| 44 | PHKG2 | 0.77239547 |
| 45 | PRKD3 | 0.74369083 |
| 46 | PRKCH | 0.71835779 |
| 47 | NLK | 0.70385242 |
| 48 | MAP2K2 | 0.69761387 |
| 49 | ERN1 | 0.69444998 |
| 50 | GRK7 | 0.63546775 |
| 51 | RPS6KA6 | 0.63003202 |
| 52 | IRAK3 | 0.56295232 |
| 53 | NEK2 | 0.56039793 |
| 54 | PLK1 | 0.54734801 |
| 55 | WNK3 | 0.53015015 |
| 56 | CSNK1E | 0.50848765 |
| 57 | CDC7 | 0.50042380 |
| 58 | PRKCQ | 0.47964664 |
| 59 | PAK1 | 0.47369576 |
| 60 | PLK3 | 0.46307305 |
| 61 | MAPKAPK5 | 0.46077665 |
| 62 | STK39 | 0.45901932 |
| 63 | RPS6KA1 | 0.45336441 |
| 64 | MKNK2 | 0.44603739 |
| 65 | RPS6KL1 | 0.42602593 |
| 66 | RPS6KC1 | 0.42602593 |
| 67 | MAP4K2 | 0.41996049 |
| 68 | TAOK1 | 0.40587193 |
| 69 | TAF1 | 0.40173840 |
| 70 | CHEK2 | 0.39481023 |
| 71 | MAPK13 | 0.38582116 |
| 72 | DYRK3 | 0.37635461 |
| 73 | CAMK2A | 0.37300407 |
| 74 | MAP3K4 | 0.36822868 |
| 75 | PKN1 | 0.35949570 |
| 76 | STK11 | 0.35811355 |
| 77 | PIM1 | 0.35368894 |
| 78 | NME1 | 0.32996604 |
| 79 | MAPK3 | 0.32959279 |
| 80 | CSNK1A1 | 0.32771030 |
| 81 | NTRK3 | 0.32387368 |
| 82 | PRKG1 | 0.31824071 |
| 83 | CASK | 0.31727191 |
| 84 | SGK1 | 0.31176233 |
| 85 | INSRR | 0.29651787 |
| 86 | PRKAA1 | 0.29516119 |
| 87 | ERBB2 | 0.29322912 |
| 88 | GSK3B | 0.28914164 |
| 89 | ITK | 0.28768877 |
| 90 | PAK6 | 0.28430475 |
| 91 | AKT1 | 0.28185960 |
| 92 | PRKACA | 0.28168142 |
| 93 | TNIK | 0.25498220 |
| 94 | FGFR2 | 0.25379685 |
| 95 | MAPK14 | 0.24947854 |
| 96 | FGFR1 | 0.24919242 |
| 97 | PRKCA | 0.24308815 |
| 98 | AURKB | 0.23781484 |
| 99 | MAPK15 | 0.23491878 |
| 100 | PRKCB | 0.23058936 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Phototransduction_Homo sapiens_hsa04744 | 2.99119684 |
| 2 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 2.94107423 |
| 3 | Nicotine addiction_Homo sapiens_hsa05033 | 2.86876545 |
| 4 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.70469879 |
| 5 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 2.42860001 |
| 6 | Morphine addiction_Homo sapiens_hsa05032 | 2.33726401 |
| 7 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.30121618 |
| 8 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 2.26115187 |
| 9 | Olfactory transduction_Homo sapiens_hsa04740 | 2.24424098 |
| 10 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 2.22999546 |
| 11 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.10143570 |
| 12 | Notch signaling pathway_Homo sapiens_hsa04330 | 2.09310630 |
| 13 | ABC transporters_Homo sapiens_hsa02010 | 2.05251221 |
| 14 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 2.03081082 |
| 15 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.96820006 |
| 16 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.89979553 |
| 17 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.81243453 |
| 18 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.81167086 |
| 19 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.80131647 |
| 20 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.66323054 |
| 21 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.63880237 |
| 22 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.63756580 |
| 23 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.63188799 |
| 24 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.59568077 |
| 25 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.56107301 |
| 26 | Long-term depression_Homo sapiens_hsa04730 | 1.46605073 |
| 27 | Homologous recombination_Homo sapiens_hsa03440 | 1.43995651 |
| 28 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 1.39567990 |
| 29 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.36640381 |
| 30 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.32040297 |
| 31 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.30966457 |
| 32 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.30051958 |
| 33 | Taste transduction_Homo sapiens_hsa04742 | 1.29069380 |
| 34 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.27678594 |
| 35 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.26649072 |
| 36 | Base excision repair_Homo sapiens_hsa03410 | 1.25584274 |
| 37 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.23421865 |
| 38 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.20296065 |
| 39 | Retinol metabolism_Homo sapiens_hsa00830 | 1.18962962 |
| 40 | Circadian entrainment_Homo sapiens_hsa04713 | 1.17572906 |
| 41 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.14611471 |
| 42 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.13269968 |
| 43 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.12933263 |
| 44 | Salivary secretion_Homo sapiens_hsa04970 | 1.09342853 |
| 45 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.06847006 |
| 46 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.06590363 |
| 47 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 1.05689371 |
| 48 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.03200377 |
| 49 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.02435170 |
| 50 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.98739874 |
| 51 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.96822187 |
| 52 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.88417413 |
| 53 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.87027793 |
| 54 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.85195030 |
| 55 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.80377862 |
| 56 | GABAergic synapse_Homo sapiens_hsa04727 | 0.77523701 |
| 57 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.76932494 |
| 58 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.72236333 |
| 59 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.68014964 |
| 60 | Histidine metabolism_Homo sapiens_hsa00340 | 0.67521150 |
| 61 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.65353328 |
| 62 | Basal transcription factors_Homo sapiens_hsa03022 | 0.64433780 |
| 63 | Platelet activation_Homo sapiens_hsa04611 | 0.62949379 |
| 64 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.62251556 |
| 65 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.60956372 |
| 66 | Bile secretion_Homo sapiens_hsa04976 | 0.60850867 |
| 67 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.60362408 |
| 68 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.59629964 |
| 69 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.55975969 |
| 70 | Lysine degradation_Homo sapiens_hsa00310 | 0.55845155 |
| 71 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.54683967 |
| 72 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.54675793 |
| 73 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.53548867 |
| 74 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.53485528 |
| 75 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.52991309 |
| 76 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.51692156 |
| 77 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.50718281 |
| 78 | Insulin secretion_Homo sapiens_hsa04911 | 0.49723358 |
| 79 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.49491202 |
| 80 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.48884174 |
| 81 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.46230289 |
| 82 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.42183128 |
| 83 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.42033094 |
| 84 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.38409116 |
| 85 | Gap junction_Homo sapiens_hsa04540 | 0.38290775 |
| 86 | Asthma_Homo sapiens_hsa05310 | 0.37819543 |
| 87 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.37168316 |
| 88 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.36772437 |
| 89 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.36336202 |
| 90 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.35424908 |
| 91 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.35412431 |
| 92 | Metabolic pathways_Homo sapiens_hsa01100 | 0.35387575 |
| 93 | Peroxisome_Homo sapiens_hsa04146 | 0.34627427 |
| 94 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.34509798 |
| 95 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.31791566 |
| 96 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.31007125 |
| 97 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.29916254 |
| 98 | Purine metabolism_Homo sapiens_hsa00230 | 0.29025413 |
| 99 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.27965118 |
| 100 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.26118550 |

