CBX1P3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of cytosolic calcium ion concentration (GO:0051481)6.80860396
2thalamus development (GO:0021794)6.13881398
3negative regulation of cAMP-mediated signaling (GO:0043951)5.74800471
4positive regulation of cAMP-mediated signaling (GO:0043950)5.54422048
5negative regulation of calcium ion-dependent exocytosis (GO:0045955)5.41147776
6behavioral response to ethanol (GO:0048149)5.35625560
7epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)5.34755931
8meiotic chromosome segregation (GO:0045132)5.27427168
9opioid receptor signaling pathway (GO:0038003)5.24619040
10response to xenobiotic stimulus (GO:0009410)4.90032200
11regulation of ER to Golgi vesicle-mediated transport (GO:0060628)4.69503582
12retinal cone cell development (GO:0046549)4.68683301
13kinetochore organization (GO:0051383)4.60161496
14sphingosine metabolic process (GO:0006670)4.55676290
15adult feeding behavior (GO:0008343)4.45547867
16positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc4.44645401
17regulation of protein glycosylation (GO:0060049)4.34684601
18regulation of meiosis I (GO:0060631)4.24551220
19cell proliferation in forebrain (GO:0021846)4.10039645
20sphingoid metabolic process (GO:0046519)4.03876687
21snRNA transcription (GO:0009301)4.03814264
22ether lipid metabolic process (GO:0046485)4.02312183
23fucose catabolic process (GO:0019317)4.02041337
24L-fucose metabolic process (GO:0042354)4.02041337
25L-fucose catabolic process (GO:0042355)4.02041337
26diol metabolic process (GO:0034311)3.96898590
27transmission of nerve impulse (GO:0019226)3.96673165
28cellular biogenic amine catabolic process (GO:0042402)3.94603015
29amine catabolic process (GO:0009310)3.94603015
30regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.94257707
31regulation of glutamate receptor signaling pathway (GO:1900449)3.91691104
32notochord development (GO:0030903)3.89976584
33intra-S DNA damage checkpoint (GO:0031573)3.88220944
34positive regulation of histone deacetylation (GO:0031065)3.84520341
35adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)3.78686120
36piRNA metabolic process (GO:0034587)3.75262717
37regulation of glucokinase activity (GO:0033131)3.71896477
38regulation of hexokinase activity (GO:1903299)3.71896477
39cysteine metabolic process (GO:0006534)3.68600809
40positive regulation of neuroblast proliferation (GO:0002052)3.68119685
41regulation of hippo signaling (GO:0035330)3.67414194
42regulation of acrosome reaction (GO:0060046)3.60820673
43regulation of cAMP-mediated signaling (GO:0043949)3.55922313
44regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)3.54795712
45replication fork processing (GO:0031297)3.53214671
46urate metabolic process (GO:0046415)3.47567159
47histone H3-K9 modification (GO:0061647)3.46193963
48negative regulation of astrocyte differentiation (GO:0048712)3.45163860
49somatic diversification of immune receptors via somatic mutation (GO:0002566)3.43323995
50somatic hypermutation of immunoglobulin genes (GO:0016446)3.43323995
51N-terminal protein amino acid acetylation (GO:0006474)3.37645567
52polyamine biosynthetic process (GO:0006596)3.31247336
53behavioral response to nicotine (GO:0035095)3.29984635
54thrombin receptor signaling pathway (GO:0070493)3.27858981
55cellular biogenic amine biosynthetic process (GO:0042401)3.26852190
56cornea development in camera-type eye (GO:0061303)3.19005872
57epithelial cilium movement (GO:0003351)3.17090302
58regulation of translational termination (GO:0006449)3.09997556
59amine biosynthetic process (GO:0009309)3.04982056
60regulation of neuroblast proliferation (GO:1902692)3.02734999
61regulation of odontogenesis of dentin-containing tooth (GO:0042487)2.97324303
62white fat cell differentiation (GO:0050872)2.96285953
63regulation of thymocyte apoptotic process (GO:0070243)2.94501308
64regulation of non-canonical Wnt signaling pathway (GO:2000050)2.92407716
65arginine catabolic process (GO:0006527)2.88879584
66superoxide anion generation (GO:0042554)2.82234881
67heart valve formation (GO:0003188)2.77741235
68L-ascorbic acid metabolic process (GO:0019852)2.77010966
69protein import into peroxisome matrix (GO:0016558)2.76909183
70forebrain neuron differentiation (GO:0021879)2.75905810
71negative regulation of thymocyte apoptotic process (GO:0070244)2.73017902
72synaptic transmission, glutamatergic (GO:0035249)2.71980932
73negative regulation of hematopoietic progenitor cell differentiation (GO:1901533)2.71635974
74detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.70269132
75negative regulation by host of viral transcription (GO:0043922)2.69994799
76axoneme assembly (GO:0035082)2.69856345
77cAMP catabolic process (GO:0006198)2.69827009
78regulation of posttranscriptional gene silencing (GO:0060147)2.67412426
79regulation of gene silencing by miRNA (GO:0060964)2.67412426
80regulation of gene silencing by RNA (GO:0060966)2.67412426
81photoreceptor cell maintenance (GO:0045494)2.67328442
82cellular response to alkaloid (GO:0071312)2.66792035
83double-strand break repair via homologous recombination (GO:0000724)2.65840158
84regulation of gamma-delta T cell differentiation (GO:0045586)2.65490726
85smooth muscle tissue development (GO:0048745)2.65395418
86cardiolipin metabolic process (GO:0032048)2.64498682
87recombinational repair (GO:0000725)2.63906609
88glycerol metabolic process (GO:0006071)2.63091333
89positive regulation of neural precursor cell proliferation (GO:2000179)2.62917375
90maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.59991163
91regulation of synapse maturation (GO:0090128)2.59800600
92cellular response to sterol (GO:0036315)2.57888882
93negative regulation of histone acetylation (GO:0035067)2.57460823
94negative regulation of adenylate cyclase activity (GO:0007194)2.57402750
95positive regulation of protein deacetylation (GO:0090312)2.56496548
96regulation of timing of cell differentiation (GO:0048505)2.56091681
97inner ear receptor stereocilium organization (GO:0060122)2.55692972
98negative regulation of nitric oxide biosynthetic process (GO:0045019)2.55118675
99resolution of meiotic recombination intermediates (GO:0000712)2.53628922
100centriole replication (GO:0007099)2.53084275

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.49913783
2VDR_22108803_ChIP-Seq_LS180_Human3.16203401
3TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.98674267
4POU5F1_26923725_Chip-Seq_MESODERM_Mouse2.98674267
5ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.55054722
6ZNF274_21170338_ChIP-Seq_K562_Hela2.47732320
7RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.46412574
8GBX2_23144817_ChIP-Seq_PC3_Human2.44999001
9GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.43537571
10ZFP57_27257070_Chip-Seq_ESCs_Mouse2.38301436
11FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.36649756
12IRF1_19129219_ChIP-ChIP_H3396_Human2.33720986
13GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.26724321
14PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.18199849
15P300_19829295_ChIP-Seq_ESCs_Human2.00011659
16CTBP2_25329375_ChIP-Seq_LNCAP_Human1.85897408
17TAF15_26573619_Chip-Seq_HEK293_Human1.84131771
18IGF1R_20145208_ChIP-Seq_DFB_Human1.81897098
19SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.79162456
20BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.76174891
21FOXM1_23109430_ChIP-Seq_U2OS_Human1.63629361
22POU3F2_20337985_ChIP-ChIP_501MEL_Human1.62266339
23CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.60742620
24CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.58744242
25CBX2_27304074_Chip-Seq_ESCs_Mouse1.58309241
26TCF4_23295773_ChIP-Seq_U87_Human1.57681912
27RXR_22108803_ChIP-Seq_LS180_Human1.55518806
28EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.53382686
29STAT3_23295773_ChIP-Seq_U87_Human1.52170381
30CTBP1_25329375_ChIP-Seq_LNCAP_Human1.50851967
31AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.49977239
32NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.48793112
33SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.47698793
34EZH2_27304074_Chip-Seq_ESCs_Mouse1.47263883
35ER_23166858_ChIP-Seq_MCF-7_Human1.46976338
36BCAT_22108803_ChIP-Seq_LS180_Human1.46213153
37PIAS1_25552417_ChIP-Seq_VCAP_Human1.44749609
38FLI1_27457419_Chip-Seq_LIVER_Mouse1.41697719
39JARID2_20064375_ChIP-Seq_MESCs_Mouse1.41685155
40FUS_26573619_Chip-Seq_HEK293_Human1.40010711
41REST_21632747_ChIP-Seq_MESCs_Mouse1.39460123
42KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.38846310
43MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.38624820
44DROSHA_22980978_ChIP-Seq_HELA_Human1.38452723
45SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.35478160
46UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.34763368
47PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.33269732
48PCGF2_27294783_Chip-Seq_NPCs_Mouse1.32608700
49RNF2_27304074_Chip-Seq_NSC_Mouse1.31386280
50EED_16625203_ChIP-ChIP_MESCs_Mouse1.31313698
51EWS_26573619_Chip-Seq_HEK293_Human1.30378586
52NANOG_19829295_ChIP-Seq_ESCs_Human1.29369806
53SOX2_19829295_ChIP-Seq_ESCs_Human1.29369806
54EZH2_27294783_Chip-Seq_ESCs_Mouse1.28530473
55PCGF2_27294783_Chip-Seq_ESCs_Mouse1.27984348
56RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.26883646
57GATA3_21878914_ChIP-Seq_MCF-7_Human1.26611632
58TOP2B_26459242_ChIP-Seq_MCF-7_Human1.26574621
59MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.24419170
60SMAD3_21741376_ChIP-Seq_EPCs_Human1.22977783
61SMAD4_21799915_ChIP-Seq_A2780_Human1.22450099
62NR3C1_21868756_ChIP-Seq_MCF10A_Human1.21827768
63TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.20991332
64AR_25329375_ChIP-Seq_VCAP_Human1.20644494
65TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.20565172
66TCF4_22108803_ChIP-Seq_LS180_Human1.20522805
67FLI1_21867929_ChIP-Seq_TH2_Mouse1.19079848
68RNF2_27304074_Chip-Seq_ESCs_Mouse1.17523212
69CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.16294414
70TAL1_26923725_Chip-Seq_HPCs_Mouse1.15931904
71SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.15066797
72SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.14650904
73NOTCH1_21737748_ChIP-Seq_TLL_Human1.14098544
74CDX2_19796622_ChIP-Seq_MESCs_Mouse1.13116986
75TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.12375937
76SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.11235864
77HOXB7_26014856_ChIP-Seq_BT474_Human1.09920778
78REST_18959480_ChIP-ChIP_MESCs_Mouse1.09427137
79SOX2_21211035_ChIP-Seq_LN229_Gbm1.07769112
80BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.07628830
81JARID2_20075857_ChIP-Seq_MESCs_Mouse1.06210853
82CDX2_22108803_ChIP-Seq_LS180_Human1.06154025
83HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.06080633
84AR_21572438_ChIP-Seq_LNCaP_Human1.06007834
85IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.05837960
86CBP_20019798_ChIP-Seq_JUKART_Human1.05837960
87SUZ12_27294783_Chip-Seq_ESCs_Mouse1.05741425
88TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.04983443
89ARNT_22903824_ChIP-Seq_MCF-7_Human1.04930859
90SMAD4_21741376_ChIP-Seq_HESCs_Human1.04345779
91LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.03366113
92PRDM14_20953172_ChIP-Seq_ESCs_Human1.03036052
93BMI1_23680149_ChIP-Seq_NPCS_Mouse1.02852305
94LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.02828560
95OCT1_27270436_Chip-Seq_PROSTATE_Human1.02568113
96SMAD3_21741376_ChIP-Seq_HESCs_Human1.00930887
97SMAD4_21741376_ChIP-Seq_EPCs_Human1.00683655
98MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.00129632
99JUN_21703547_ChIP-Seq_K562_Human0.99721898
100SUZ12_27294783_Chip-Seq_NPCs_Mouse0.99035509

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003136_yellow_coat_color4.31938995
2MP0005085_abnormal_gallbladder_physiolo3.67139739
3MP0001968_abnormal_touch/_nociception3.36771735
4MP0002653_abnormal_ependyma_morphology3.18582004
5MP0002138_abnormal_hepatobiliary_system3.16093552
6MP0003890_abnormal_embryonic-extraembry3.05491126
7MP0003646_muscle_fatigue2.86860279
8MP0002876_abnormal_thyroid_physiology2.80742016
9MP0008057_abnormal_DNA_replication2.78195349
10MP0006292_abnormal_olfactory_placode2.44317021
11MP0005083_abnormal_biliary_tract2.42202417
12MP0002837_dystrophic_cardiac_calcinosis2.33836306
13MP0003252_abnormal_bile_duct2.33331472
14MP0005365_abnormal_bile_salt2.21536218
15MP0009278_abnormal_bone_marrow2.06150869
16MP0001486_abnormal_startle_reflex2.01603891
17MP0008872_abnormal_physiological_respon1.97386357
18MP0009764_decreased_sensitivity_to1.96435183
19MP0005645_abnormal_hypothalamus_physiol1.93742409
20MP0002736_abnormal_nociception_after1.91953898
21MP0003879_abnormal_hair_cell1.91519055
22MP0008877_abnormal_DNA_methylation1.88676692
23MP0003718_maternal_effect1.79512735
24MP0001501_abnormal_sleep_pattern1.79276436
25MP0005551_abnormal_eye_electrophysiolog1.79054395
26MP0002733_abnormal_thermal_nociception1.75215432
27MP0004142_abnormal_muscle_tone1.74761147
28MP0003045_fibrosis1.74043384
29MP0008004_abnormal_stomach_pH1.71029807
30MP0001664_abnormal_digestion1.64480068
31MP0005646_abnormal_pituitary_gland1.59832948
32MP0005360_urolithiasis1.57019320
33MP0008875_abnormal_xenobiotic_pharmacok1.56180427
34MP0002272_abnormal_nervous_system1.51976750
35MP0009745_abnormal_behavioral_response1.50076151
36MP0004145_abnormal_muscle_electrophysio1.46295767
37MP0003633_abnormal_nervous_system1.44587152
38MP0005423_abnormal_somatic_nervous1.36945381
39MP0001970_abnormal_pain_threshold1.36776374
40MP0009697_abnormal_copulation1.35021685
41MP0003937_abnormal_limbs/digits/tail_de1.33253222
42MP0003787_abnormal_imprinting1.31126943
43MP0003880_abnormal_central_pattern1.30510925
44MP0002163_abnormal_gland_morphology1.28973191
45MP0002557_abnormal_social/conspecific_i1.28152368
46MP0009053_abnormal_anal_canal1.27462875
47MP0001440_abnormal_grooming_behavior1.27067549
48MP0001529_abnormal_vocalization1.23524376
49MP0002822_catalepsy1.22178446
50MP0000678_abnormal_parathyroid_gland1.20183389
51MP0002572_abnormal_emotion/affect_behav1.15998769
52MP0005464_abnormal_platelet_physiology1.14869357
53MP0000778_abnormal_nervous_system1.13892098
54MP0000383_abnormal_hair_follicle1.13769322
55MP0005670_abnormal_white_adipose1.12573077
56MP0002249_abnormal_larynx_morphology1.11653209
57MP0008569_lethality_at_weaning1.06651509
58MP0003959_abnormal_lean_body1.06585078
59MP0002067_abnormal_sensory_capabilities1.05296757
60MP0000049_abnormal_middle_ear1.00411651
61MP0006072_abnormal_retinal_apoptosis1.00073635
62MP0000230_abnormal_systemic_arterial0.95273804
63MP0004924_abnormal_behavior0.94371338
64MP0005386_behavior/neurological_phenoty0.94371338
65MP0004147_increased_porphyrin_level0.93573924
66MP0001545_abnormal_hematopoietic_system0.92102028
67MP0005397_hematopoietic_system_phenotyp0.92102028
68MP0002752_abnormal_somatic_nervous0.91390306
69MP0002063_abnormal_learning/memory/cond0.90955105
70MP0002064_seizures0.90441174
71MP0002184_abnormal_innervation0.90286247
72MP0005409_darkened_coat_color0.89890461
73MP0003195_calcinosis0.86782970
74MP0009780_abnormal_chondrocyte_physiolo0.86340935
75MP0005503_abnormal_tendon_morphology0.83722683
76MP0004742_abnormal_vestibular_system0.83180318
77MP0008058_abnormal_DNA_repair0.82909859
78MP0004043_abnormal_pH_regulation0.82900453
79MP0003631_nervous_system_phenotype0.80027069
80MP0003638_abnormal_response/metabolism_0.79935240
81MP0003635_abnormal_synaptic_transmissio0.79318110
82MP0000026_abnormal_inner_ear0.78467467
83MP0009046_muscle_twitch0.77226227
84MP0005195_abnormal_posterior_eye0.76855487
85MP0002229_neurodegeneration0.76444170
86MP0001963_abnormal_hearing_physiology0.74830745
87MP0000015_abnormal_ear_pigmentation0.74524117
88MP0000955_abnormal_spinal_cord0.74245719
89MP0003567_abnormal_fetal_cardiomyocyte0.73702483
90MP0000428_abnormal_craniofacial_morphol0.70969282
91MP0000427_abnormal_hair_cycle0.70793139
92MP0003122_maternal_imprinting0.70203431
93MP0004085_abnormal_heartbeat0.69108765
94MP0003698_abnormal_male_reproductive0.67572501
95MP0003938_abnormal_ear_development0.67212801
96MP0000631_abnormal_neuroendocrine_gland0.66632217
97MP0002090_abnormal_vision0.66318227
98MP0006035_abnormal_mitochondrial_morpho0.66169766
99MP0005395_other_phenotype0.65450193
100MP0005377_hearing/vestibular/ear_phenot0.64451225

Predicted human phenotypes

RankGene SetZ-score
1Thyroid-stimulating hormone excess (HP:0002925)5.78901550
2Absent rod-and cone-mediated responses on ERG (HP:0007688)5.67448687
3Intestinal atresia (HP:0011100)4.80615599
4Aplasia/Hypoplasia of the spleen (HP:0010451)4.37643726
5Optic nerve hypoplasia (HP:0000609)4.36076820
6Abnormal rod and cone electroretinograms (HP:0008323)4.35163327
7Volvulus (HP:0002580)4.29884667
8Tubular atrophy (HP:0000092)4.09203649
9Pancreatic islet-cell hyperplasia (HP:0004510)4.02274430
10Asplenia (HP:0001746)3.90264182
11Abnormality of the aortic arch (HP:0012303)3.78301881
12Aplasia/Hypoplasia of the optic nerve (HP:0008058)3.67963110
13Focal motor seizures (HP:0011153)3.65955899
14Abnormality of the labia minora (HP:0012880)3.56476575
15Pancreatic cysts (HP:0001737)3.54519484
16Type II lissencephaly (HP:0007260)3.43217124
17Broad alveolar ridges (HP:0000187)3.25396519
18Abnormality of the ileum (HP:0001549)3.21173087
19Tented upper lip vermilion (HP:0010804)3.17049417
20Conjugated hyperbilirubinemia (HP:0002908)3.07400317
21Agitation (HP:0000713)3.06359338
22Abnormality of the renal cortex (HP:0011035)3.06161365
23Large for gestational age (HP:0001520)3.05931698
24Colon cancer (HP:0003003)3.00520966
25Attenuation of retinal blood vessels (HP:0007843)2.99725394
26Increased density of long bones (HP:0006392)2.98868342
27Pendular nystagmus (HP:0012043)2.84575110
28Pancreatic fibrosis (HP:0100732)2.82227917
29Nephronophthisis (HP:0000090)2.69663731
30Molar tooth sign on MRI (HP:0002419)2.68634404
31Abnormality of midbrain morphology (HP:0002418)2.68634404
32Gastrointestinal atresia (HP:0002589)2.66797738
33Abnormality of the renal medulla (HP:0100957)2.66731657
34Polydipsia (HP:0001959)2.61737479
35Abnormal drinking behavior (HP:0030082)2.61737479
36Abnormality of macular pigmentation (HP:0008002)2.54152145
37Aplasia/Hypoplasia of the uvula (HP:0010293)2.50859742
38Oligodontia (HP:0000677)2.42925049
39Aplasia/Hypoplasia affecting the fundus (HP:0008057)2.39973166
40Petechiae (HP:0000967)2.36156789
41Supernumerary spleens (HP:0009799)2.33659922
42Abnormal biliary tract physiology (HP:0012439)2.24961585
43Bile duct proliferation (HP:0001408)2.24961585
44Tubulointerstitial fibrosis (HP:0005576)2.21467585
45Bony spicule pigmentary retinopathy (HP:0007737)2.19748155
46Potter facies (HP:0002009)2.17264292
47Facial shape deformation (HP:0011334)2.17264292
48Retinal dysplasia (HP:0007973)2.15376816
49Fair hair (HP:0002286)2.14712727
50Cerebellar dysplasia (HP:0007033)2.14312566
51Pigmentary retinal degeneration (HP:0001146)2.14219389
52Gaze-evoked nystagmus (HP:0000640)2.13618130
53Hyperventilation (HP:0002883)2.12760169
54Hyperthyroidism (HP:0000836)2.10867693
55Abnormality of endocrine pancreas physiology (HP:0012093)2.09899164
56Abnormality of the pancreatic islet cells (HP:0006476)2.09899164
57Thickened helices (HP:0000391)2.09729962
58True hermaphroditism (HP:0010459)2.08459480
59Nephroblastoma (Wilms tumor) (HP:0002667)2.08115347
60Focal seizures (HP:0007359)2.08010011
61Dyschromatopsia (HP:0007641)2.07510920
62Chronic hepatic failure (HP:0100626)2.04701226
63Enlarged kidneys (HP:0000105)2.04548806
64Decreased central vision (HP:0007663)2.02072010
65Decreased muscle mass (HP:0003199)2.01557857
66Cystic liver disease (HP:0006706)2.00355912
67Severe visual impairment (HP:0001141)1.96058929
68Febrile seizures (HP:0002373)1.95912957
69Short 1st metacarpal (HP:0010034)1.95404751
70Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.95404751
71Vitreoretinal degeneration (HP:0000655)1.94769475
72Meckel diverticulum (HP:0002245)1.94579719
73Embryonal renal neoplasm (HP:0011794)1.94437516
74Increased corneal curvature (HP:0100692)1.93935180
75Keratoconus (HP:0000563)1.93935180
76Congenital stationary night blindness (HP:0007642)1.93416074
77Duodenal stenosis (HP:0100867)1.91794556
78Small intestinal stenosis (HP:0012848)1.91794556
79Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.91588869
80Short 4th metacarpal (HP:0010044)1.91588869
81Chromsome breakage (HP:0040012)1.89433498
82Hypophosphatemic rickets (HP:0004912)1.88765083
83J-shaped sella turcica (HP:0002680)1.88552664
84Chromosomal breakage induced by crosslinking agents (HP:0003221)1.86197674
85Dandy-Walker malformation (HP:0001305)1.82635813
86Lissencephaly (HP:0001339)1.81268533
87Gingival bleeding (HP:0000225)1.79213711
88Hematochezia (HP:0002573)1.78629058
89Polyuria (HP:0000103)1.78438718
90Rib fusion (HP:0000902)1.76929681
91Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.76440310
92Abnormality of the carotid arteries (HP:0005344)1.75937344
93Abnormality of the duodenum (HP:0002246)1.74722868
94Central scotoma (HP:0000603)1.74086785
95Increased mean platelet volume (HP:0011877)1.69854070
96Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.69548712
97Abnormality of the 1st metacarpal (HP:0010009)1.69126177
98Amelogenesis imperfecta (HP:0000705)1.66055468
99Hypoplastic labia majora (HP:0000059)1.65773338
100Poor head control (HP:0002421)1.64536562

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ADRBK25.02462703
2CCNB14.72753781
3PKN24.12379232
4FRK3.96476733
5FLT33.21393097
6ARAF3.13541576
7MAP3K103.05252804
8ACVR1B2.54497561
9LATS12.40926920
10PIM22.31418619
11HIPK22.12592044
12PINK12.06273492
13BMPR1B2.04323701
14BRAF1.96499639
15NUAK11.88819948
16GRK11.79686469
17ZAK1.69586051
18ADRBK11.59907794
19PNCK1.58937502
20WNK41.56482944
21STK38L1.51387967
22DYRK21.51369285
23STK161.51165862
24PRKCI1.47011794
25TGFBR11.43279245
26TEC1.36638787
27LMTK21.34345518
28RAF11.28603884
29MELK1.21818878
30PRKCE1.18562628
31TAOK31.18170224
32PRKCG1.17558351
33EIF2AK11.08758840
34GRK51.03920202
35PTK2B0.98191322
36PAK30.96078862
37PLK20.95352387
38BMX0.94684233
39WEE10.92138120
40LATS20.85247332
41STK30.84517608
42TIE10.78328840
43PHKG10.77239547
44PHKG20.77239547
45PRKD30.74369083
46PRKCH0.71835779
47NLK0.70385242
48MAP2K20.69761387
49ERN10.69444998
50GRK70.63546775
51RPS6KA60.63003202
52IRAK30.56295232
53NEK20.56039793
54PLK10.54734801
55WNK30.53015015
56CSNK1E0.50848765
57CDC70.50042380
58PRKCQ0.47964664
59PAK10.47369576
60PLK30.46307305
61MAPKAPK50.46077665
62STK390.45901932
63RPS6KA10.45336441
64MKNK20.44603739
65RPS6KL10.42602593
66RPS6KC10.42602593
67MAP4K20.41996049
68TAOK10.40587193
69TAF10.40173840
70CHEK20.39481023
71MAPK130.38582116
72DYRK30.37635461
73CAMK2A0.37300407
74MAP3K40.36822868
75PKN10.35949570
76STK110.35811355
77PIM10.35368894
78NME10.32996604
79MAPK30.32959279
80CSNK1A10.32771030
81NTRK30.32387368
82PRKG10.31824071
83CASK0.31727191
84SGK10.31176233
85INSRR0.29651787
86PRKAA10.29516119
87ERBB20.29322912
88GSK3B0.28914164
89ITK0.28768877
90PAK60.28430475
91AKT10.28185960
92PRKACA0.28168142
93TNIK0.25498220
94FGFR20.25379685
95MAPK140.24947854
96FGFR10.24919242
97PRKCA0.24308815
98AURKB0.23781484
99MAPK150.23491878
100PRKCB0.23058936

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047442.99119684
2Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.94107423
3Nicotine addiction_Homo sapiens_hsa050332.86876545
4Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.70469879
5Dorso-ventral axis formation_Homo sapiens_hsa043202.42860001
6Morphine addiction_Homo sapiens_hsa050322.33726401
7Caffeine metabolism_Homo sapiens_hsa002322.30121618
8Steroid hormone biosynthesis_Homo sapiens_hsa001402.26115187
9Olfactory transduction_Homo sapiens_hsa047402.24424098
10Neuroactive ligand-receptor interaction_Homo sapiens_hsa040802.22999546
11Linoleic acid metabolism_Homo sapiens_hsa005912.10143570
12Notch signaling pathway_Homo sapiens_hsa043302.09310630
13ABC transporters_Homo sapiens_hsa020102.05251221
14beta-Alanine metabolism_Homo sapiens_hsa004102.03081082
15Cysteine and methionine metabolism_Homo sapiens_hsa002701.96820006
16Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.89979553
17Arachidonic acid metabolism_Homo sapiens_hsa005901.81243453
18Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.81167086
19Butanoate metabolism_Homo sapiens_hsa006501.80131647
20Fanconi anemia pathway_Homo sapiens_hsa034601.66323054
21Glycerolipid metabolism_Homo sapiens_hsa005611.63880237
22Nitrogen metabolism_Homo sapiens_hsa009101.63756580
23Arginine biosynthesis_Homo sapiens_hsa002201.63188799
24Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.59568077
25alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.56107301
26Long-term depression_Homo sapiens_hsa047301.46605073
27Homologous recombination_Homo sapiens_hsa034401.43995651
28Ovarian steroidogenesis_Homo sapiens_hsa049131.39567990
29Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.36640381
30Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.32040297
31Tryptophan metabolism_Homo sapiens_hsa003801.30966457
32Ether lipid metabolism_Homo sapiens_hsa005651.30051958
33Taste transduction_Homo sapiens_hsa047421.29069380
34Arginine and proline metabolism_Homo sapiens_hsa003301.27678594
35Cyanoamino acid metabolism_Homo sapiens_hsa004601.26649072
36Base excision repair_Homo sapiens_hsa034101.25584274
37Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.23421865
38Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.20296065
39Retinol metabolism_Homo sapiens_hsa008301.18962962
40Circadian entrainment_Homo sapiens_hsa047131.17572906
41Starch and sucrose metabolism_Homo sapiens_hsa005001.14611471
42Serotonergic synapse_Homo sapiens_hsa047261.13269968
43Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.12933263
44Salivary secretion_Homo sapiens_hsa049701.09342853
45Chemical carcinogenesis_Homo sapiens_hsa052041.06847006
46Cardiac muscle contraction_Homo sapiens_hsa042601.06590363
47Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.05689371
48Fatty acid degradation_Homo sapiens_hsa000711.03200377
49Sphingolipid metabolism_Homo sapiens_hsa006001.02435170
50Glutamatergic synapse_Homo sapiens_hsa047240.98739874
51Non-homologous end-joining_Homo sapiens_hsa034500.96822187
52Hedgehog signaling pathway_Homo sapiens_hsa043400.88417413
53Dilated cardiomyopathy_Homo sapiens_hsa054140.87027793
54Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.85195030
55Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.80377862
56GABAergic synapse_Homo sapiens_hsa047270.77523701
57Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.76932494
58Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.72236333
59Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.68014964
60Histidine metabolism_Homo sapiens_hsa003400.67521150
61Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.65353328
62Basal transcription factors_Homo sapiens_hsa030220.64433780
63Platelet activation_Homo sapiens_hsa046110.62949379
64Glutathione metabolism_Homo sapiens_hsa004800.62251556
65Primary bile acid biosynthesis_Homo sapiens_hsa001200.60956372
66Bile secretion_Homo sapiens_hsa049760.60850867
67Propanoate metabolism_Homo sapiens_hsa006400.60362408
68Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.59629964
69Vascular smooth muscle contraction_Homo sapiens_hsa042700.55975969
70Lysine degradation_Homo sapiens_hsa003100.55845155
71Maturity onset diabetes of the young_Homo sapiens_hsa049500.54683967
72Oxytocin signaling pathway_Homo sapiens_hsa049210.54675793
73Hippo signaling pathway_Homo sapiens_hsa043900.53548867
74Steroid biosynthesis_Homo sapiens_hsa001000.53485528
75cAMP signaling pathway_Homo sapiens_hsa040240.52991309
76Carbohydrate digestion and absorption_Homo sapiens_hsa049730.51692156
77Nucleotide excision repair_Homo sapiens_hsa034200.50718281
78Insulin secretion_Homo sapiens_hsa049110.49723358
79Basal cell carcinoma_Homo sapiens_hsa052170.49491202
80Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.48884174
81ECM-receptor interaction_Homo sapiens_hsa045120.46230289
82Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.42183128
83Gastric acid secretion_Homo sapiens_hsa049710.42033094
84Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.38409116
85Gap junction_Homo sapiens_hsa045400.38290775
86Asthma_Homo sapiens_hsa053100.37819543
87Calcium signaling pathway_Homo sapiens_hsa040200.37168316
88Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.36772437
89Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.36336202
90Fat digestion and absorption_Homo sapiens_hsa049750.35424908
91Glycerophospholipid metabolism_Homo sapiens_hsa005640.35412431
92Metabolic pathways_Homo sapiens_hsa011000.35387575
93Peroxisome_Homo sapiens_hsa041460.34627427
94Systemic lupus erythematosus_Homo sapiens_hsa053220.34509798
95TGF-beta signaling pathway_Homo sapiens_hsa043500.31791566
96Complement and coagulation cascades_Homo sapiens_hsa046100.31007125
97Vitamin digestion and absorption_Homo sapiens_hsa049770.29916254
98Purine metabolism_Homo sapiens_hsa002300.29025413
99Pentose and glucuronate interconversions_Homo sapiens_hsa000400.27965118
100Intestinal immune network for IgA production_Homo sapiens_hsa046720.26118550

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »