CBX6

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)6.33745604
2locomotory exploration behavior (GO:0035641)5.96810265
3regulation of short-term neuronal synaptic plasticity (GO:0048172)5.94577859
4positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.47350996
5positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.28175349
6synaptic vesicle docking involved in exocytosis (GO:0016081)5.07151272
7vocalization behavior (GO:0071625)4.89419734
8synaptic vesicle exocytosis (GO:0016079)4.87417607
9glutamate secretion (GO:0014047)4.87004486
10regulation of synaptic vesicle exocytosis (GO:2000300)4.77989978
11regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.65150512
12layer formation in cerebral cortex (GO:0021819)4.57161241
13regulation of glutamate receptor signaling pathway (GO:1900449)4.41989080
14regulation of synapse structural plasticity (GO:0051823)4.34371624
15regulation of neuronal synaptic plasticity (GO:0048168)4.32549464
16exploration behavior (GO:0035640)4.28731117
17regulation of long-term neuronal synaptic plasticity (GO:0048169)4.25496651
18negative regulation of dendrite morphogenesis (GO:0050774)4.23021052
19dendritic spine morphogenesis (GO:0060997)4.21017649
20regulation of synaptic vesicle transport (GO:1902803)4.17146670
21sodium ion export (GO:0071436)4.15954766
22neurotransmitter secretion (GO:0007269)4.14614096
23neuronal action potential propagation (GO:0019227)4.01497920
24protein localization to synapse (GO:0035418)4.00619668
25cellular potassium ion homeostasis (GO:0030007)3.96975573
26detection of calcium ion (GO:0005513)3.94301918
27activation of protein kinase A activity (GO:0034199)3.87588882
28ionotropic glutamate receptor signaling pathway (GO:0035235)3.84190490
29myelin maintenance (GO:0043217)3.74689431
30proline transport (GO:0015824)3.71829656
31neuromuscular process controlling balance (GO:0050885)3.70552098
32membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.69072408
33cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.68755816
34long-term memory (GO:0007616)3.65607165
35positive regulation of nitric-oxide synthase activity (GO:0051000)3.56418172
36synaptic transmission, glutamatergic (GO:0035249)3.55204421
37cell communication by electrical coupling (GO:0010644)3.50547686
38long term synaptic depression (GO:0060292)3.48427853
39positive regulation of membrane potential (GO:0045838)3.47434773
40glycine transport (GO:0015816)3.44839457
41gamma-aminobutyric acid transport (GO:0015812)3.42128307
42regulation of excitatory postsynaptic membrane potential (GO:0060079)3.40955652
43regulation of dendritic spine morphogenesis (GO:0061001)3.40871563
44neurotransmitter-gated ion channel clustering (GO:0072578)3.38485687
45positive regulation of synaptic transmission, GABAergic (GO:0032230)3.37507177
46negative regulation of cell size (GO:0045792)3.36744960
47positive regulation of synapse maturation (GO:0090129)3.34750378
48regulation of type B pancreatic cell apoptotic process (GO:2000674)3.33669803
49regulation of synaptic plasticity (GO:0048167)3.32862365
50cytoskeletal anchoring at plasma membrane (GO:0007016)3.30485921
51insulin secretion (GO:0030073)3.29791471
52G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.27776008
53neuron-neuron synaptic transmission (GO:0007270)3.27035948
54positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.26579993
55glutamate receptor signaling pathway (GO:0007215)3.26127073
56positive regulation of actin filament depolymerization (GO:0030836)3.26077253
57dendritic spine organization (GO:0097061)3.25605382
58regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.25465274
59neuron cell-cell adhesion (GO:0007158)3.25019795
60regulation of ARF protein signal transduction (GO:0032012)3.24762639
61prepulse inhibition (GO:0060134)3.21503803
62neurotransmitter transport (GO:0006836)3.21422014
63regulation of postsynaptic membrane potential (GO:0060078)3.20244807
64negative regulation of synaptic transmission, GABAergic (GO:0032229)3.19177662
65positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.18978890
66auditory behavior (GO:0031223)3.14423264
67neuronal ion channel clustering (GO:0045161)3.11962870
68regulation of neurotransmitter secretion (GO:0046928)3.11344973
69dendrite morphogenesis (GO:0048813)3.11132146
70signal release (GO:0023061)3.08240218
71cerebellar Purkinje cell layer development (GO:0021680)3.07736734
72astrocyte differentiation (GO:0048708)3.04891918
73cerebellar Purkinje cell differentiation (GO:0021702)3.04242793
74response to gravity (GO:0009629)3.04069190
75neuromuscular process controlling posture (GO:0050884)3.03642739
76potassium ion import (GO:0010107)3.02556743
77positive regulation of protein dephosphorylation (GO:0035307)3.01085432
78vesicle transport along microtubule (GO:0047496)2.99658057
79regulation of neurotransmitter levels (GO:0001505)2.98131052
80regulation of vesicle fusion (GO:0031338)2.97327104
81long-term synaptic potentiation (GO:0060291)2.95039186
82positive regulation of neurotransmitter transport (GO:0051590)2.94824292
83synaptic vesicle endocytosis (GO:0048488)2.94365986
84negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.93673753
85transmission of nerve impulse (GO:0019226)2.92602495
86response to auditory stimulus (GO:0010996)2.92176255
87mating behavior (GO:0007617)2.91874301
88regulation of neurotransmitter transport (GO:0051588)2.91614669
89regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.90764346
90positive regulation of neurotransmitter secretion (GO:0001956)2.90601371
91regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.90077000
92vesicle docking involved in exocytosis (GO:0006904)2.89938909
93innervation (GO:0060384)2.89350250
94regulation of synapse maturation (GO:0090128)2.89094628
95membrane depolarization during action potential (GO:0086010)2.87946114
96neuron recognition (GO:0008038)2.87875743
97regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.87205709
98regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022352.84663900
99cellular sodium ion homeostasis (GO:0006883)2.83786395
100potassium ion homeostasis (GO:0055075)2.83100876
101regulation of synaptic transmission, glutamatergic (GO:0051966)2.82688107
102neuromuscular process (GO:0050905)2.82522299
103chemosensory behavior (GO:0007635)2.80883576
104membrane depolarization (GO:0051899)2.80304279
105positive regulation of gluconeogenesis (GO:0045722)2.80146425
106positive regulation of dendritic spine development (GO:0060999)2.78084962
107regulation of exocytosis (GO:0017157)2.77446710
108regulation of dendritic spine development (GO:0060998)2.76491445
109membrane hyperpolarization (GO:0060081)2.75965537
110cerebellar granule cell differentiation (GO:0021707)2.75722417
111membrane repolarization (GO:0086009)2.75339336
112positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.75154406
113axonal fasciculation (GO:0007413)2.75078591
114establishment of nucleus localization (GO:0040023)2.74909001
115cell migration in hindbrain (GO:0021535)2.74742470
116negative regulation of hormone biosynthetic process (GO:0032353)2.74312007
117positive regulation of synaptic transmission (GO:0050806)2.73246959
118positive regulation of fibroblast migration (GO:0010763)2.72445279
119regulation of voltage-gated calcium channel activity (GO:1901385)2.71318409
120regulation of clathrin-mediated endocytosis (GO:2000369)2.69838051
121regulation of synaptic transmission (GO:0050804)2.68837404
122epithelial cell fate commitment (GO:0072148)2.68540899
123response to ischemia (GO:0002931)2.68248623
124positive regulation of Rap GTPase activity (GO:0032854)2.66906836
125regulation of protein sumoylation (GO:0033233)2.66853133
126suckling behavior (GO:0001967)2.66323437
127cell communication involved in cardiac conduction (GO:0086065)2.66012307
128positive regulation of protein sumoylation (GO:0033235)2.65996750
129membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.62629462
130regulation of calcium ion-dependent exocytosis (GO:0017158)2.61363926
131positive regulation of insulin secretion involved in cellular response to glucose stimulus (GO:003572.58940008
132negative regulation of execution phase of apoptosis (GO:1900118)2.57308252
133regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.56990319
134positive regulation of macroautophagy (GO:0016239)2.55939512
135negative regulation of dendrite development (GO:2000171)2.53761836
136positive regulation of insulin secretion (GO:0032024)2.51973887
137regulation of neurotransmitter uptake (GO:0051580)2.49470364
138regulation of protein dephosphorylation (GO:0035304)2.48984016
139glycerophospholipid catabolic process (GO:0046475)2.47607467
140negative regulation of glycogen metabolic process (GO:0070874)2.45040734
141inositol phosphate catabolic process (GO:0071545)2.44074256
142synaptic vesicle transport (GO:0048489)2.43503855
143establishment of synaptic vesicle localization (GO:0097480)2.43503855
144protein maturation by protein folding (GO:0022417)2.42955899

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse5.99054015
2EZH2_22144423_ChIP-Seq_EOC_Human5.09986058
3SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.96874593
4* RARB_27405468_Chip-Seq_BRAIN_Mouse2.95916416
5SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.93205113
6JARID2_20064375_ChIP-Seq_MESCs_Mouse2.87956601
7DROSHA_22980978_ChIP-Seq_HELA_Human2.83104898
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.82226447
9EZH2_18974828_ChIP-Seq_MESCs_Mouse2.82226447
10EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.68844593
11BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.68007927
12JARID2_20075857_ChIP-Seq_MESCs_Mouse2.67188892
13MTF2_20144788_ChIP-Seq_MESCs_Mouse2.57932944
14SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.53732875
15SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.45787797
16SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.45729870
17REST_21632747_ChIP-Seq_MESCs_Mouse2.42330649
18MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.41814329
19SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.35516949
20EZH2_27304074_Chip-Seq_ESCs_Mouse2.32212727
21IKZF1_21737484_ChIP-ChIP_HCT116_Human2.29580004
22SUZ12_27294783_Chip-Seq_ESCs_Mouse2.29498457
23EZH2_27294783_Chip-Seq_ESCs_Mouse2.27819238
24RNF2_27304074_Chip-Seq_ESCs_Mouse2.25503454
25REST_18959480_ChIP-ChIP_MESCs_Mouse2.10278470
26EED_16625203_ChIP-ChIP_MESCs_Mouse2.09966855
27GBX2_23144817_ChIP-Seq_PC3_Human2.08911323
28ERG_21242973_ChIP-ChIP_JURKAT_Human1.90617328
29CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.88112060
30ZFP281_18757296_ChIP-ChIP_E14_Mouse1.86462452
31KDM2B_26808549_Chip-Seq_K562_Human1.81376255
32ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.79479478
33* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.78288356
34RACK7_27058665_Chip-Seq_MCF-7_Human1.72724662
35DNAJC2_21179169_ChIP-ChIP_NT2_Human1.70121705
36TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.67055835
37NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.63975353
38EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.58112796
39AR_21572438_ChIP-Seq_LNCaP_Human1.55872418
40SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.50706925
41P68_20966046_ChIP-Seq_HELA_Human1.48504335
42RING1B_27294783_Chip-Seq_ESCs_Mouse1.48460056
43KDM2B_26808549_Chip-Seq_SUP-B15_Human1.48020986
44ZFP281_27345836_Chip-Seq_ESCs_Mouse1.46878493
45* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.46793286
46SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.45403191
47KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.41429669
48TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.36424113
49* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.35276457
50GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.33309105
51DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.32708550
52* TET1_21451524_ChIP-Seq_MESCs_Mouse1.32048344
53* RING1B_27294783_Chip-Seq_NPCs_Mouse1.27326435
54SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.26353566
55ELF1_20517297_ChIP-Seq_JURKAT_Human1.25046445
56GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.22644468
57AR_19668381_ChIP-Seq_PC3_Human1.21410956
58LXR_22292898_ChIP-Seq_THP-1_Human1.19668982
59TCF7_22412390_ChIP-Seq_EML_Mouse1.19181839
60KDM2B_26808549_Chip-Seq_DND41_Human1.18650029
61NR3C1_23031785_ChIP-Seq_PC12_Mouse1.17579460
62PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.16523712
63ELK3_25401928_ChIP-Seq_HUVEC_Human1.15879414
64ZNF274_21170338_ChIP-Seq_K562_Hela1.15317778
65SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.14189469
66STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.14091962
67KDM2B_26808549_Chip-Seq_JURKAT_Human1.12459572
68STAT6_21828071_ChIP-Seq_BEAS2B_Human1.12284878
69CTCF_27219007_Chip-Seq_ERYTHROID_Human1.12018403
70CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.11951548
71ZNF217_24962896_ChIP-Seq_MCF-7_Human1.11854666
72E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.11278772
73SOX2_21211035_ChIP-Seq_LN229_Gbm1.11123811
74ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.10323254
75CTCF_27219007_Chip-Seq_Bcells_Human1.09266535
76TRIM28_21343339_ChIP-Seq_HEK293_Human1.09260655
77SMAD4_21799915_ChIP-Seq_A2780_Human1.09040909
78TET1_21490601_ChIP-Seq_MESCs_Mouse1.08654136
79ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.08333586
80KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.05879716
81NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.05698091
82CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.05456391
83* FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.05122024
84SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.04975894
85CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.03122094
86EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.03119319
87CTBP2_25329375_ChIP-Seq_LNCAP_Human1.02954388
88RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.02931718
89* ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.02912562
90THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.01637265
91ESR2_21235772_ChIP-Seq_MCF-7_Human1.01210592
92SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.00036470
93YAP1_20516196_ChIP-Seq_MESCs_Mouse0.99525785
94* SA1_27219007_Chip-Seq_ERYTHROID_Human0.98229505
95* OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.98200812
96SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.98039852
97DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.96977572
98* MYC_22102868_ChIP-Seq_BL_Human0.96068621
99TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.95773192
100AHR_22903824_ChIP-Seq_MCF-7_Human0.95508576
101TP53_20018659_ChIP-ChIP_R1E_Mouse0.95393180
102SMC4_20622854_ChIP-Seq_HELA_Human0.95036035
103SRY_22984422_ChIP-ChIP_TESTIS_Rat0.94368400
104SMAD3_21741376_ChIP-Seq_HESCs_Human0.93899921
105SMAD4_21741376_ChIP-Seq_HESCs_Human0.93826720
106PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.93525095
107CREB1_26743006_Chip-Seq_LNCaP_Human0.92603257
108ARNT_22903824_ChIP-Seq_MCF-7_Human0.91952834
109SMAD3_21741376_ChIP-Seq_ESCs_Human0.91466334
110EP300_21415370_ChIP-Seq_HL-1_Mouse0.91039995
111SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.91038096
112VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.90952029
113PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.90855472
114BCOR_27268052_Chip-Seq_Bcells_Human0.90514848
115RAD21_21589869_ChIP-Seq_MESCs_Mouse0.89872755
116VDR_21846776_ChIP-Seq_THP-1_Human0.89715817
117TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.89600278
118KLF4_19829295_ChIP-Seq_ESCs_Human0.89150322
119* MITF_21258399_ChIP-Seq_MELANOMA_Human0.88511410
120CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.87798676
121ESR1_20079471_ChIP-ChIP_T-47D_Human0.87714714
122CTBP1_25329375_ChIP-Seq_LNCAP_Human0.87278996
123UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.86857337
124P53_22127205_ChIP-Seq_FIBROBLAST_Human0.86624099
125RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.86604990
126* RARB_24833708_ChIP-Seq_LIVER_Mouse0.86050092
127RARG_19884340_ChIP-ChIP_MEFs_Mouse0.85895253
128STAT3_23295773_ChIP-Seq_U87_Human0.85819038
129PKCTHETA_26484144_Chip-Seq_BREAST_Human0.85649121
130CTNNB1_20460455_ChIP-Seq_HCT116_Human0.85351371
131RXR_22108803_ChIP-Seq_LS180_Human0.85077653
132P300_27058665_Chip-Seq_ZR-75-30cells_Human0.84282615
133SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.84069834
134TP53_16413492_ChIP-PET_HCT116_Human0.84002194
135TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.82702009
136MAF_26560356_Chip-Seq_TH2_Human0.82701433
137SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.82507081
138TP53_23651856_ChIP-Seq_MEFs_Mouse0.82382148
139SMAD_19615063_ChIP-ChIP_OVARY_Human0.82348249
140CDX2_19796622_ChIP-Seq_MESCs_Mouse0.81373411
141MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.81224976
142AR_25329375_ChIP-Seq_VCAP_Human0.80196029

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.95761359
2MP0003635_abnormal_synaptic_transmissio4.08257925
3MP0004270_analgesia3.61144090
4MP0003880_abnormal_central_pattern3.60518569
5MP0002063_abnormal_learning/memory/cond3.14790947
6MP0002822_catalepsy3.13988458
7MP0009745_abnormal_behavioral_response3.11339608
8MP0002064_seizures2.87157575
9MP0009046_muscle_twitch2.63253315
10MP0009780_abnormal_chondrocyte_physiolo2.58005029
11MP0001968_abnormal_touch/_nociception2.52208740
12MP0002572_abnormal_emotion/affect_behav2.45877688
13MP0002734_abnormal_mechanical_nocicepti2.39754583
14MP0002909_abnormal_adrenal_gland2.37457803
15MP0004858_abnormal_nervous_system2.34666638
16MP0002272_abnormal_nervous_system2.34107182
17MP0005423_abnormal_somatic_nervous2.32849857
18MP0005379_endocrine/exocrine_gland_phen2.25398115
19MP0001486_abnormal_startle_reflex2.22965512
20MP0008569_lethality_at_weaning2.10266161
21MP0001944_abnormal_pancreas_morphology2.08459223
22MP0003283_abnormal_digestive_organ2.05367553
23MP0002163_abnormal_gland_morphology1.98483982
24MP0002693_abnormal_pancreas_physiology1.91613923
25MP0003329_amyloid_beta_deposits1.89484148
26MP0001501_abnormal_sleep_pattern1.89262277
27MP0002733_abnormal_thermal_nociception1.85287171
28MP0004811_abnormal_neuron_physiology1.83839220
29MP0001970_abnormal_pain_threshold1.82543056
30MP0002736_abnormal_nociception_after1.72497971
31MP0002735_abnormal_chemical_nociception1.70194102
32MP0004885_abnormal_endolymph1.67997823
33MP0001440_abnormal_grooming_behavior1.66819122
34MP0002184_abnormal_innervation1.63428782
35MP0005623_abnormal_meninges_morphology1.61120370
36MP0000955_abnormal_spinal_cord1.58178676
37MP0000013_abnormal_adipose_tissue1.57396776
38MP0002067_abnormal_sensory_capabilities1.56577490
39MP0002557_abnormal_social/conspecific_i1.54742987
40MP0003879_abnormal_hair_cell1.47203992
41MP0008961_abnormal_basal_metabolism1.46674683
42MP0004924_abnormal_behavior1.40812245
43MP0005386_behavior/neurological_phenoty1.40812245
44MP0000751_myopathy1.40698025
45MP0000778_abnormal_nervous_system1.40665155
46MP0010234_abnormal_vibrissa_follicle1.40581288
47MP0002166_altered_tumor_susceptibility1.39737362
48MP0003633_abnormal_nervous_system1.37994785
49MP0002876_abnormal_thyroid_physiology1.34232562
50MP0002882_abnormal_neuron_morphology1.33587097
51MP0002066_abnormal_motor_capabilities/c1.30359431
52MP0000015_abnormal_ear_pigmentation1.26483755
53MP0003123_paternal_imprinting1.22508980
54MP0003787_abnormal_imprinting1.19025880
55MP0003075_altered_response_to1.16750073
56MP0003122_maternal_imprinting1.15933478
57MP0005220_abnormal_exocrine_pancreas1.14509393
58MP0005646_abnormal_pituitary_gland1.13847183
59MP0004145_abnormal_muscle_electrophysio1.12167271
60MP0001765_abnormal_ion_homeostasis1.10980657
61MP0003631_nervous_system_phenotype1.08593305
62MP0002152_abnormal_brain_morphology1.05802575
63MP0000639_abnormal_adrenal_gland1.03385928
64MP0005167_abnormal_blood-brain_barrier1.03267104
65MP0001177_atelectasis1.01701524
66MP0001756_abnormal_urination1.00933648
67MP0002078_abnormal_glucose_homeostasis0.99427269
68MP0002234_abnormal_pharynx_morphology0.98649670
69MP0001502_abnormal_circadian_rhythm0.97894480
70MP0001299_abnormal_eye_distance/0.96819709
71MP0005645_abnormal_hypothalamus_physiol0.96700305
72MP0010386_abnormal_urinary_bladder0.95959958
73MP0001984_abnormal_olfaction0.95529388
74MP0002928_abnormal_bile_duct0.92971206
75MP0001958_emphysema0.91853116
76MP0005367_renal/urinary_system_phenotyp0.91034349
77MP0000516_abnormal_urinary_system0.91034349
78MP0003634_abnormal_glial_cell0.91009918
79MP0004233_abnormal_muscle_weight0.90468039
80MP0002006_tumorigenesis0.89828045
81MP0004085_abnormal_heartbeat0.88404880
82MP0005058_abnormal_lysosome_morphology0.88272825
83MP0008874_decreased_physiological_sensi0.86854835
84MP0000534_abnormal_ureter_morphology0.86639585
85MP0003045_fibrosis0.86159081
86MP0002069_abnormal_eating/drinking_beha0.85875783
87MP0000681_abnormal_thyroid_gland0.84511645
88MP0001346_abnormal_lacrimal_gland0.84401199
89MP0000613_abnormal_salivary_gland0.80422924
90MP0000003_abnormal_adipose_tissue0.79612529
91MP0004043_abnormal_pH_regulation0.79485491
92MP0001348_abnormal_lacrimal_gland0.79113756
93MP0000538_abnormal_urinary_bladder0.77462561
94MP0000920_abnormal_myelination0.76933139
95MP0002295_abnormal_pulmonary_circulatio0.76781691
96MP0008872_abnormal_physiological_respon0.76247877
97MP0002229_neurodegeneration0.76152670
98MP0000569_abnormal_digit_pigmentation0.75405100
99MP0005310_abnormal_salivary_gland0.73997240
100MP0003632_abnormal_nervous_system0.73928914
101MP0002090_abnormal_vision0.72978241
102MP0002638_abnormal_pupillary_reflex0.72812531
103MP0002837_dystrophic_cardiac_calcinosis0.72556813
104MP0004142_abnormal_muscle_tone0.71409472
105MP0003690_abnormal_glial_cell0.71248119
106MP0002089_abnormal_postnatal_growth/wei0.70830608
107MP0005166_decreased_susceptibility_to0.70669668
108MP0003172_abnormal_lysosome_physiology0.70346822
109MP0010352_gastrointestinal_tract_polyps0.69842709
110MP0003137_abnormal_impulse_conducting0.69824871
111MP0006276_abnormal_autonomic_nervous0.69220265
112MP0003953_abnormal_hormone_level0.68453666
113MP0001905_abnormal_dopamine_level0.67678047
114MP0000631_abnormal_neuroendocrine_gland0.67539696
115MP0000747_muscle_weakness0.67363258
116MP0005174_abnormal_tail_pigmentation0.66990463
117MP0001664_abnormal_digestion0.65690943
118MP0006072_abnormal_retinal_apoptosis0.65356639
119MP0005448_abnormal_energy_balance0.64761435
120MP0000604_amyloidosis0.64237017
121MP0002877_abnormal_melanocyte_morpholog0.63937857
122MP0001943_abnormal_respiration0.62497200
123MP0004215_abnormal_myocardial_fiber0.62232383
124MP0005394_taste/olfaction_phenotype0.61920483
125MP0005499_abnormal_olfactory_system0.61920483
126MP0005187_abnormal_penis_morphology0.60728103
127MP0003279_aneurysm0.60401470
128MP0001986_abnormal_taste_sensitivity0.58634705
129MP0003861_abnormal_nervous_system0.58252368
130MP0004484_altered_response_of0.58072171
131MP0004130_abnormal_muscle_cell0.58010278
132MP0001485_abnormal_pinna_reflex0.57937182
133MP0005535_abnormal_body_temperature0.57907219
134MP0008438_abnormal_cutaneous_collagen0.57126528
135MP0004510_myositis0.56844312
136MP0002752_abnormal_somatic_nervous0.55279001

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)6.43836923
2Focal motor seizures (HP:0011153)5.37742680
3Visual hallucinations (HP:0002367)4.69241749
4Focal seizures (HP:0007359)4.51424845
5Action tremor (HP:0002345)4.00118953
6Hyperthyroidism (HP:0000836)3.89476345
7Enlarged penis (HP:0000040)3.44532225
8Papilledema (HP:0001085)3.39298494
9Supranuclear gaze palsy (HP:0000605)3.36543071
10Ankle clonus (HP:0011448)3.35772890
11Atonic seizures (HP:0010819)3.34778464
12Progressive cerebellar ataxia (HP:0002073)3.30685530
13Epileptic encephalopathy (HP:0200134)3.26998205
14Depression (HP:0000716)3.25246025
15Stridor (HP:0010307)3.10940739
16Hyperglycemia (HP:0003074)3.09215956
17Ventricular fibrillation (HP:0001663)2.97618536
18Absence seizures (HP:0002121)2.97367130
19Hamartoma of the eye (HP:0010568)2.96682734
20Hyperinsulinemic hypoglycemia (HP:0000825)2.93678007
21Insomnia (HP:0100785)2.93045528
22Annular pancreas (HP:0001734)2.92881552
23Hypoglycemic seizures (HP:0002173)2.92547358
24Ketoacidosis (HP:0001993)2.91853271
25Abnormality of the lower motor neuron (HP:0002366)2.84253679
26Poor eye contact (HP:0000817)2.82828897
27Febrile seizures (HP:0002373)2.80900398
28Generalized tonic-clonic seizures (HP:0002069)2.80834067
29Megalencephaly (HP:0001355)2.80637009
30Urethral obstruction (HP:0000796)2.80531771
31Impaired vibration sensation in the lower limbs (HP:0002166)2.78659160
32Testicular neoplasm (HP:0010788)2.77445971
33Pointed chin (HP:0000307)2.75078053
34Torticollis (HP:0000473)2.73559859
35Anxiety (HP:0000739)2.72688466
36Dysdiadochokinesis (HP:0002075)2.70311438
37Mucopolysacchariduria (HP:0008155)2.70239627
38Urinary glycosaminoglycan excretion (HP:0003541)2.70239627
39Abnormality of polysaccharide metabolism (HP:0011012)2.69994314
40Abnormality of glycosaminoglycan metabolism (HP:0004371)2.69994314
41Abnormality of mucopolysaccharide metabolism (HP:0011020)2.69994314
42Abnormal social behavior (HP:0012433)2.63654826
43Impaired social interactions (HP:0000735)2.63654826
44Hemiplegia (HP:0002301)2.61707031
45Congenital malformation of the right heart (HP:0011723)2.61675016
46Double outlet right ventricle (HP:0001719)2.61675016
47Dialeptic seizures (HP:0011146)2.61552596
48Postural instability (HP:0002172)2.60368996
49Urinary bladder sphincter dysfunction (HP:0002839)2.58710271
50Ocular albinism (HP:0001107)2.56811274
51Dysmetria (HP:0001310)2.56550315
52J-shaped sella turcica (HP:0002680)2.53563686
53Hypsarrhythmia (HP:0002521)2.53394672
54Truncal ataxia (HP:0002078)2.53103360
55Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.50773324
56Hypokinesia (HP:0002375)2.50298215
57Genetic anticipation (HP:0003743)2.49228752
58Hyperacusis (HP:0010780)2.47950973
59Focal dystonia (HP:0004373)2.45110988
60Gaze-evoked nystagmus (HP:0000640)2.44917435
61Dysostosis multiplex (HP:0000943)2.44590985
62Increased CSF protein (HP:0002922)2.42817112
63Impaired smooth pursuit (HP:0007772)2.41995257
64Urinary urgency (HP:0000012)2.41859322
65Bundle branch block (HP:0011710)2.41752796
66Insulin-resistant diabetes mellitus (HP:0000831)2.40950679
67Broad-based gait (HP:0002136)2.40941079
68Abnormality of aromatic amino acid family metabolism (HP:0004338)2.40852416
69Dysmetric saccades (HP:0000641)2.40735680
70Late onset (HP:0003584)2.40232133
71Intention tremor (HP:0002080)2.40097500
72Amblyopia (HP:0000646)2.39929114
73Asymmetry of the thorax (HP:0001555)2.37898875
74Ankyloglossia (HP:0010296)2.36961995
75Neoplasm of the adrenal cortex (HP:0100641)2.34396677
76Testicular atrophy (HP:0000029)2.33485593
77Hypoglycemic coma (HP:0001325)2.31683127
78Akinesia (HP:0002304)2.31113988
79Tetraplegia (HP:0002445)2.30701152
80Conjunctival hamartoma (HP:0100780)2.30109919
81Mutism (HP:0002300)2.28532812
82Resting tremor (HP:0002322)2.28204791
83Tongue fasciculations (HP:0001308)2.27868991
84Abnormal eating behavior (HP:0100738)2.27647716
85Cutaneous melanoma (HP:0012056)2.27139762
86Cerebral inclusion bodies (HP:0100314)2.25670682
87Obstructive sleep apnea (HP:0002870)2.23994336
88Cerebral hypomyelination (HP:0006808)2.22462430
89Stereotypic behavior (HP:0000733)2.22450992
90Iris hypopigmentation (HP:0007730)2.20414835
91Craniofacial dystonia (HP:0012179)2.19782268
92Progressive neurologic deterioration (HP:0002344)2.19674974
93Unilateral renal agenesis (HP:0000122)2.18539841
94Hypercortisolism (HP:0001578)2.18443426
95Spastic gait (HP:0002064)2.17925405
96Hypoventilation (HP:0002791)2.17130430
97Truncus arteriosus (HP:0001660)2.14009719
98Delusions (HP:0000746)2.09635578
99Macroorchidism (HP:0000053)2.09607415
100Scanning speech (HP:0002168)2.09569017
101Hyperphosphatemia (HP:0002905)2.09217622
102Termporal pattern (HP:0011008)2.08990750
103Insidious onset (HP:0003587)2.08990750
104Neurofibrillary tangles (HP:0002185)2.08922779
105Neoplasm of the heart (HP:0100544)2.07180104
106Bradykinesia (HP:0002067)2.06243991
107Abnormality of ocular smooth pursuit (HP:0000617)2.04477330
108Large for gestational age (HP:0001520)2.03230452
109Bronchomalacia (HP:0002780)2.02428708
110Hemiparesis (HP:0001269)2.01135002
111Agitation (HP:0000713)1.99959315
112Rigidity (HP:0002063)1.99455389
113Congenital glaucoma (HP:0001087)1.99361547
114Limb ataxia (HP:0002070)1.99279134
115Rapidly progressive (HP:0003678)1.98953548
116Elfin facies (HP:0004428)1.98214353
117Distal upper limb amyotrophy (HP:0007149)1.98082851
118Upper limb amyotrophy (HP:0009129)1.98082851
119Diminished movement (HP:0002374)1.97840628
120Overriding aorta (HP:0002623)1.95636488
121Muscular hypotonia of the trunk (HP:0008936)1.94497565
122Lower limb amyotrophy (HP:0007210)1.93994323
123Hyperparathyroidism (HP:0000843)1.93881026
124Lower limb asymmetry (HP:0100559)1.91647901
125Abnormality of endocrine pancreas physiology (HP:0012093)1.91576186
126Abnormality of the pancreatic islet cells (HP:0006476)1.91576186
127Sensory axonal neuropathy (HP:0003390)1.91039170
128Growth hormone excess (HP:0000845)1.90713240
129Hematochezia (HP:0002573)1.89704777
130Shallow orbits (HP:0000586)1.89643809
131Abnormality of oral frenula (HP:0000190)1.89345244
132Lower limb muscle weakness (HP:0007340)1.89206340
133Sleep apnea (HP:0010535)1.89153939
134Spinal canal stenosis (HP:0003416)1.89046172
135Insulin resistance (HP:0000855)1.87878790
136Muscle fibrillation (HP:0010546)1.87354119
137Heterochromia iridis (HP:0001100)1.86584420
138Achilles tendon contracture (HP:0001771)1.86556485
139Nuclear cataract (HP:0100018)1.84602964
140Abnormal EKG (HP:0003115)1.83883670
141Diplopia (HP:0000651)1.83154935
142Abnormality of binocular vision (HP:0011514)1.83154935
143Buphthalmos (HP:0000557)1.79290455
144Aplasia involving bones of the extremities (HP:0009825)1.79179176
145Aplasia involving bones of the upper limbs (HP:0009823)1.79179176
146Aplasia of the phalanges of the hand (HP:0009802)1.79179176
147Bowel diverticulosis (HP:0005222)1.79122395
148Prolonged QT interval (HP:0001657)1.78355045
149Pheochromocytoma (HP:0002666)1.74964099
150Cerebral aneurysm (HP:0004944)1.74644973
151Clonus (HP:0002169)1.74526369
152Impaired vibratory sensation (HP:0002495)1.72900260
153Apathy (HP:0000741)1.72047611
154Broad metatarsal (HP:0001783)1.71942419
155Neuronal loss in central nervous system (HP:0002529)1.71851442
156EEG with generalized epileptiform discharges (HP:0011198)1.70865771
157Epileptiform EEG discharges (HP:0011182)1.70280869
158Increased variability in muscle fiber diameter (HP:0003557)1.70069083
159Postural tremor (HP:0002174)1.68935026

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK4.12811962
2EPHA43.93998819
3NTRK33.89622497
4MAP3K93.82670422
5PRKD33.01912900
6DAPK22.72788230
7KSR22.63811195
8PAK62.58404952
9MINK12.46152336
10CAMKK12.43100823
11NTRK12.40632252
12MAP3K42.17380296
13MARK12.08084761
14TRIB31.80741778
15NTRK21.75059384
16MAP3K21.68704615
17STK381.63853424
18RIPK11.60871851
19TYRO31.57524749
20LIMK11.53757582
21CDK51.52346441
22TESK11.52126765
23SMG11.48787341
24TAOK11.43102640
25KSR11.42387608
26DAPK11.39401170
27UHMK11.37856590
28LMTK21.37562832
29MAP2K71.29774901
30PRKCH1.29370295
31FGFR31.27803624
32MAP2K41.26368178
33ALK1.26286682
34CAMKK21.25806155
35SIK21.24907533
36RET1.24170758
37LATS21.24161110
38MAPKAPK31.22722862
39DDR21.20430894
40BMPR21.19672986
41PDGFRA1.17581355
42PRKCI1.17358254
43PRPF4B1.13378118
44ARAF1.09146617
45GRK51.08483860
46IRAK31.07246283
47JAK11.06862792
48SCYL21.06759664
49MST41.04833012
50PKN21.04688193
51RIPK41.04648871
52CDK191.03503782
53CAMK11.01184314
54FES1.00885353
55PHKG21.00286192
56PHKG11.00286192
57PAK31.00207782
58MARK20.95541589
59SIK10.95286199
60MAP3K130.94864592
61PRKCG0.94660836
62STK110.90273339
63MAP2K60.90036590
64CDK150.89806385
65CDK180.86746346
66CDK140.85996044
67MAP3K10.85237246
68WNK10.79268689
69CDK11A0.78593233
70FER0.77520670
71IRAK20.77147109
72PLK20.76816060
73DMPK0.76743207
74CDC42BPA0.76229310
75PTK2B0.75528055
76NEK10.75074035
77MAP3K120.75023988
78CAMK2G0.74110157
79RAF10.73751376
80PDK10.73218734
81PDPK10.72490970
82GRK10.72156844
83MAP3K70.71924721
84MAP3K110.69909366
85MAPK120.69759872
86SGK2230.68739777
87SGK4940.68739777
88TRPM70.68569794
89DAPK30.66557740
90CAMK2A0.65307931
91MAPK130.65117865
92SGK30.64683040
93PINK10.64016772
94ICK0.63900290
95EEF2K0.63889841
96MAPK110.63456670
97PRKD20.62778219
98CAMK1G0.61943905
99PNCK0.59701531
100MYLK0.59332873
101TNK20.59198902
102CAMK2B0.58895114
103MAP2K10.56979277
104TNIK0.56493838
105BMX0.56231173
106CAMK40.54264151
107PTK20.53843995
108BRSK10.53214296
109SGK10.52072087
110CHUK0.51373186
111FYN0.51077960
112FGFR20.50656198
113RPS6KA30.49572735
114ROCK10.49330729
115FGFR40.48053201
116SGK20.47960007
117PIM20.47809256
118EPHA20.47168804
119HIPK20.46710368
120RPS6KA20.46506093
121CSNK1G20.45487782
122PRKG20.45236130
123ROCK20.45171322
124PRKCE0.44958353
125MAPK100.44111156
126CAMK2D0.43740364
127AKT20.43577631
128ILK0.42443954
129OXSR10.41103548
130PRKD10.40747418
131PRKCZ0.40618089
132EPHB10.40577890
133PRKAA10.39263689
134MAP4K10.38142597

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007503.68475565
2Synaptic vesicle cycle_Homo sapiens_hsa047212.83370388
3Maturity onset diabetes of the young_Homo sapiens_hsa049502.77714354
4Olfactory transduction_Homo sapiens_hsa047402.61195684
5Nicotine addiction_Homo sapiens_hsa050332.54858529
6Circadian entrainment_Homo sapiens_hsa047132.41975946
7Long-term potentiation_Homo sapiens_hsa047202.41574273
8Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.40320172
9GABAergic synapse_Homo sapiens_hsa047272.30295037
10Glutamatergic synapse_Homo sapiens_hsa047242.23603003
11Amphetamine addiction_Homo sapiens_hsa050312.19744012
12Morphine addiction_Homo sapiens_hsa050322.10774749
13Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.10712640
14Insulin secretion_Homo sapiens_hsa049112.05979911
15Salivary secretion_Homo sapiens_hsa049702.00909963
16Gastric acid secretion_Homo sapiens_hsa049711.98613750
17Dopaminergic synapse_Homo sapiens_hsa047281.96789107
18Cholinergic synapse_Homo sapiens_hsa047251.89007152
19Aldosterone synthesis and secretion_Homo sapiens_hsa049251.88702258
20Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.77029633
21Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.68228132
22Cocaine addiction_Homo sapiens_hsa050301.65405913
23Oxytocin signaling pathway_Homo sapiens_hsa049211.62074337
24Renin secretion_Homo sapiens_hsa049241.54396464
25Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.54233564
26GnRH signaling pathway_Homo sapiens_hsa049121.52593070
27Long-term depression_Homo sapiens_hsa047301.49222460
28Gap junction_Homo sapiens_hsa045401.43791203
29Nitrogen metabolism_Homo sapiens_hsa009101.43197956
30Taste transduction_Homo sapiens_hsa047421.42424045
31Glioma_Homo sapiens_hsa052141.40157314
32Estrogen signaling pathway_Homo sapiens_hsa049151.34906528
33Calcium signaling pathway_Homo sapiens_hsa040201.34392178
34Type II diabetes mellitus_Homo sapiens_hsa049301.32750836
35SNARE interactions in vesicular transport_Homo sapiens_hsa041301.31023030
36cAMP signaling pathway_Homo sapiens_hsa040241.24750211
37Serotonergic synapse_Homo sapiens_hsa047261.23984413
38Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.23054442
39Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.22852938
40Glycosaminoglycan degradation_Homo sapiens_hsa005311.20275392
41Melanogenesis_Homo sapiens_hsa049161.17670916
42Phosphatidylinositol signaling system_Homo sapiens_hsa040701.17100930
43cGMP-PKG signaling pathway_Homo sapiens_hsa040221.12042709
44ErbB signaling pathway_Homo sapiens_hsa040121.04732741
45Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.03416899
46Phospholipase D signaling pathway_Homo sapiens_hsa040721.02395332
47Axon guidance_Homo sapiens_hsa043601.01927125
48Dorso-ventral axis formation_Homo sapiens_hsa043201.00816943
49Pancreatic secretion_Homo sapiens_hsa049721.00628030
50Vascular smooth muscle contraction_Homo sapiens_hsa042700.99247798
51Dilated cardiomyopathy_Homo sapiens_hsa054140.98769978
52Thyroid hormone synthesis_Homo sapiens_hsa049180.98275013
53Folate biosynthesis_Homo sapiens_hsa007900.96640735
54Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.95489315
55Neurotrophin signaling pathway_Homo sapiens_hsa047220.89309185
56VEGF signaling pathway_Homo sapiens_hsa043700.88258860
57mTOR signaling pathway_Homo sapiens_hsa041500.86026642
58Oocyte meiosis_Homo sapiens_hsa041140.86007079
59Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.84681186
60Carbohydrate digestion and absorption_Homo sapiens_hsa049730.83935965
61Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.83822506
62Thyroid hormone signaling pathway_Homo sapiens_hsa049190.82236195
63Endometrial cancer_Homo sapiens_hsa052130.75820683
64Rap1 signaling pathway_Homo sapiens_hsa040150.75819195
65Choline metabolism in cancer_Homo sapiens_hsa052310.75413848
66Non-small cell lung cancer_Homo sapiens_hsa052230.74240156
67Collecting duct acid secretion_Homo sapiens_hsa049660.74148018
68Endocytosis_Homo sapiens_hsa041440.73479087
69Other glycan degradation_Homo sapiens_hsa005110.73141607
70Vibrio cholerae infection_Homo sapiens_hsa051100.72919676
71MAPK signaling pathway_Homo sapiens_hsa040100.72682956
72Lysosome_Homo sapiens_hsa041420.71690372
73Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.71312561
74Cardiac muscle contraction_Homo sapiens_hsa042600.70642665
75Glucagon signaling pathway_Homo sapiens_hsa049220.65871573
76Renal cell carcinoma_Homo sapiens_hsa052110.65077977
77Longevity regulating pathway - mammal_Homo sapiens_hsa042110.63889426
78Regulation of autophagy_Homo sapiens_hsa041400.62446863
79AMPK signaling pathway_Homo sapiens_hsa041520.61630615
80Ras signaling pathway_Homo sapiens_hsa040140.61400283
81Sphingolipid signaling pathway_Homo sapiens_hsa040710.61094563
82Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.60583564
83Insulin signaling pathway_Homo sapiens_hsa049100.57946845
84Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.57763306
85N-Glycan biosynthesis_Homo sapiens_hsa005100.55758003
86Wnt signaling pathway_Homo sapiens_hsa043100.55567823
87Inositol phosphate metabolism_Homo sapiens_hsa005620.55503042
88Alcoholism_Homo sapiens_hsa050340.55132917
89Bile secretion_Homo sapiens_hsa049760.53885395
90Focal adhesion_Homo sapiens_hsa045100.53066382
91Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.52351669
92Tight junction_Homo sapiens_hsa045300.51296828
93Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.51049835
94Central carbon metabolism in cancer_Homo sapiens_hsa052300.50931444
95Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.50028069
96Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.49897704
97Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.49487436
98Proteoglycans in cancer_Homo sapiens_hsa052050.49248309
99Platelet activation_Homo sapiens_hsa046110.49001964
100Prion diseases_Homo sapiens_hsa050200.48523415
101T cell receptor signaling pathway_Homo sapiens_hsa046600.48452301
102Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.47980525
103Circadian rhythm_Homo sapiens_hsa047100.47502139
104Phototransduction_Homo sapiens_hsa047440.47356093
105Prolactin signaling pathway_Homo sapiens_hsa049170.44836171
106Regulation of actin cytoskeleton_Homo sapiens_hsa048100.44092425
107Colorectal cancer_Homo sapiens_hsa052100.43405789
108Chemokine signaling pathway_Homo sapiens_hsa040620.42856849
109Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.42711787
110Type I diabetes mellitus_Homo sapiens_hsa049400.42088170
111Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.41382055
112Bladder cancer_Homo sapiens_hsa052190.40961030
113Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.40926605
114Hippo signaling pathway_Homo sapiens_hsa043900.40592240
115Insulin resistance_Homo sapiens_hsa049310.39454247
116Adipocytokine signaling pathway_Homo sapiens_hsa049200.37512367
117Sulfur metabolism_Homo sapiens_hsa009200.37162565
118Ovarian steroidogenesis_Homo sapiens_hsa049130.34875252
119B cell receptor signaling pathway_Homo sapiens_hsa046620.34443016
120Sphingolipid metabolism_Homo sapiens_hsa006000.32769365
121Protein export_Homo sapiens_hsa030600.31964857
122Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.31447089
123Primary immunodeficiency_Homo sapiens_hsa053400.29984744
124Mineral absorption_Homo sapiens_hsa049780.29600852
125Rheumatoid arthritis_Homo sapiens_hsa053230.27321014

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