CBX8

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1viral transcription (GO:0019083)7.88268940
2ribosomal small subunit biogenesis (GO:0042274)7.71489110
3translational termination (GO:0006415)7.47321875
4SRP-dependent cotranslational protein targeting to membrane (GO:0006614)6.49120801
5cotranslational protein targeting to membrane (GO:0006613)6.47477406
6protein targeting to ER (GO:0045047)6.39781921
7neuron cell-cell adhesion (GO:0007158)6.27767775
8establishment of protein localization to endoplasmic reticulum (GO:0072599)6.18921461
9protein localization to endoplasmic reticulum (GO:0070972)6.03263899
10translational elongation (GO:0006414)5.90957116
11presynaptic membrane assembly (GO:0097105)5.84535614
12cellular protein complex disassembly (GO:0043624)5.73652010
13ribosomal small subunit assembly (GO:0000028)5.66082739
14postsynaptic membrane organization (GO:0001941)5.60141362
15viral life cycle (GO:0019058)5.47556317
16nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)5.45318826
17regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.14422359
18maturation of SSU-rRNA (GO:0030490)5.11926640
19presynaptic membrane organization (GO:0097090)5.11569639
20protein complex disassembly (GO:0043241)5.10015526
21macromolecular complex disassembly (GO:0032984)4.69657306
22pyrimidine nucleobase catabolic process (GO:0006208)4.59297445
23translational initiation (GO:0006413)4.51823352
24regulation of chromatin binding (GO:0035561)4.38814018
25protein targeting to membrane (GO:0006612)4.36072370
26regulation of mammary gland epithelial cell proliferation (GO:0033599)4.32789181
27positive regulation of synapse assembly (GO:0051965)4.18076051
28positive regulation of respiratory burst (GO:0060267)4.05737958
29skeletal muscle organ development (GO:0060538)3.94734688
30diaphragm development (GO:0060539)3.86061192
31protein localization to synapse (GO:0035418)3.83317883
32ATP synthesis coupled proton transport (GO:0015986)3.81727229
33energy coupled proton transport, down electrochemical gradient (GO:0015985)3.81727229
34regulation of cell-cell adhesion mediated by cadherin (GO:2000047)3.80188433
35mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.72354686
36dermatan sulfate metabolic process (GO:0030205)3.70526822
37lymphoid progenitor cell differentiation (GO:0002320)3.67944504
38chromosome condensation (GO:0030261)3.64701670
39cell migration in hindbrain (GO:0021535)3.56095798
40nuclear-transcribed mRNA catabolic process (GO:0000956)3.54083126
41spliceosomal tri-snRNP complex assembly (GO:0000244)3.52500906
42positive regulation of synaptic transmission, GABAergic (GO:0032230)3.51718191
43regulation of glutamate receptor signaling pathway (GO:1900449)3.48828003
44nucleobase catabolic process (GO:0046113)3.46684131
45mitotic chromosome condensation (GO:0007076)3.46175564
46mitochondrion transport along microtubule (GO:0047497)3.44251079
47establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.44251079
48chondroitin sulfate catabolic process (GO:0030207)3.43867043
49regulation of translational fidelity (GO:0006450)3.40622637
50mRNA catabolic process (GO:0006402)3.40311438
51proline biosynthetic process (GO:0006561)3.35953314
52respiratory tube development (GO:0030323)3.32543727
53peptidyl-arginine omega-N-methylation (GO:0035247)3.28764066
54protein insertion into membrane (GO:0051205)3.26984481
55regulation of ER to Golgi vesicle-mediated transport (GO:0060628)3.23660012
56positive regulation of glomerulus development (GO:0090193)3.22927286
57regulation of axon extension involved in axon guidance (GO:0048841)3.22393109
58protein retention in ER lumen (GO:0006621)3.21577345
59DNA packaging (GO:0006323)3.20163553
60regulation of neuron projection regeneration (GO:0070570)3.20127670
61regulation of axon regeneration (GO:0048679)3.20127670
62membrane assembly (GO:0071709)3.20024388
63vocalization behavior (GO:0071625)3.18776081
64negative regulation of microtubule polymerization (GO:0031115)3.17311242
65regulation of axon guidance (GO:1902667)3.16076101
66folic acid metabolic process (GO:0046655)3.15043250
67apoptotic process involved in morphogenesis (GO:0060561)3.11952472
68positive regulation of collagen biosynthetic process (GO:0032967)3.11052406
69cellular protein complex localization (GO:0034629)3.09084011
70lateral sprouting from an epithelium (GO:0060601)3.07856209
71startle response (GO:0001964)3.06777037
72positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.04467544
73establishment of protein localization to membrane (GO:0090150)3.03473262
74short-term memory (GO:0007614)3.01725698
75regulation of alternative mRNA splicing, via spliceosome (GO:0000381)3.01010570
76translation (GO:0006412)3.00265151
77GDP-mannose metabolic process (GO:0019673)3.00050063
78negative regulation of erythrocyte differentiation (GO:0045647)2.98878028
79establishment of mitochondrion localization (GO:0051654)2.97401963
80DNA unwinding involved in DNA replication (GO:0006268)2.96955014
81negative regulation of DNA-templated transcription, elongation (GO:0032785)2.96831482
82post-embryonic morphogenesis (GO:0009886)2.96434038
83maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.95347083
84dendritic spine morphogenesis (GO:0060997)2.94669273
85regulation of ruffle assembly (GO:1900027)2.93804410
86protein complex localization (GO:0031503)2.93564138
87mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.93433646
88positive regulation of collagen metabolic process (GO:0010714)2.92826699
89cranial nerve morphogenesis (GO:0021602)2.92559981
90righting reflex (GO:0060013)2.91318942
91negative regulation of immunoglobulin mediated immune response (GO:0002890)2.89329891
92negative regulation of B cell mediated immunity (GO:0002713)2.89329891
93locomotory exploration behavior (GO:0035641)2.88947909
94sympathetic nervous system development (GO:0048485)2.88079531
95planar cell polarity pathway involved in neural tube closure (GO:0090179)2.87853464
96embryonic skeletal joint morphogenesis (GO:0060272)2.86920682
97body morphogenesis (GO:0010171)2.85710915
98negative regulation of execution phase of apoptosis (GO:1900118)2.85439832
99protein-DNA complex disassembly (GO:0032986)2.85262266
100nucleosome disassembly (GO:0006337)2.85262266
101exploration behavior (GO:0035640)2.84550481
102maternal behavior (GO:0042711)2.82796946
103lung epithelium development (GO:0060428)2.82622477
104blood coagulation, intrinsic pathway (GO:0007597)2.81914057
105keratinocyte development (GO:0003334)2.81553969
106RNA catabolic process (GO:0006401)2.81275447
107DNA topological change (GO:0006265)2.80315508
108regulation of synapse assembly (GO:0051963)2.79672615
109mitochondrial fusion (GO:0008053)2.79062225
110dermatan sulfate biosynthetic process (GO:0030208)2.78864159
111peptidyl-arginine N-methylation (GO:0035246)2.78210649
112peptidyl-arginine methylation (GO:0018216)2.78210649
113ribosomal large subunit biogenesis (GO:0042273)2.77879655
114ribonucleoprotein complex biogenesis (GO:0022613)2.77738785
115facial nerve structural organization (GO:0021612)2.75748863
116chaperone-mediated protein transport (GO:0072321)2.74154225
117regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.73575749
118mitotic sister chromatid segregation (GO:0000070)2.72459277
119negative regulation of catenin import into nucleus (GO:0035414)2.70255565
120chaperone-mediated protein complex assembly (GO:0051131)2.68949486
121cell-cell junction maintenance (GO:0045217)2.68367564
122embryonic body morphogenesis (GO:0010172)2.67457422
123pattern specification involved in kidney development (GO:0061004)2.64123104
124protein localization to membrane (GO:0072657)2.63933819
125positive regulation of DNA-dependent DNA replication (GO:2000105)2.63822687
126prepulse inhibition (GO:0060134)2.63549606
127eyelid development in camera-type eye (GO:0061029)2.60631542
128negative regulation of transcription by competitive promoter binding (GO:0010944)2.59334796
129positive regulation of dendritic spine morphogenesis (GO:0061003)2.58864986
130neuron recognition (GO:0008038)2.58639877
131negative regulation of cell size (GO:0045792)2.57618877
132protein targeting (GO:0006605)2.55928771
133cochlea morphogenesis (GO:0090103)2.55580877
134negative regulation of axon extension (GO:0030517)2.54337139
135microtubule severing (GO:0051013)2.53831950
136microtubule depolymerization (GO:0007019)2.53353174
137regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.52996985
138metanephric tubule development (GO:0072170)2.52841194
139metanephric nephron tubule development (GO:0072234)2.52841194
140positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.52057221
141spermatid nucleus differentiation (GO:0007289)2.51182711
142positive regulation of transcription from RNA polymerase III promoter (GO:0045945)2.50837161
143respiratory electron transport chain (GO:0022904)2.49904531
144negative regulation of axon guidance (GO:1902668)2.49771029
145regulation of collagen biosynthetic process (GO:0032965)2.48579596
146sister chromatid segregation (GO:0000819)2.47307746
147auditory behavior (GO:0031223)2.47073765
148positive regulation of dendritic spine development (GO:0060999)2.46182726
149electron transport chain (GO:0022900)2.45983296
150secretory granule organization (GO:0033363)2.45940809
151negative regulation of axon extension involved in axon guidance (GO:0048843)2.45564916
152histone H2B ubiquitination (GO:0033523)2.44511170
153lung morphogenesis (GO:0060425)2.44173016
154positive regulation of receptor biosynthetic process (GO:0010870)2.43326132
155apoptotic process involved in development (GO:1902742)2.43051365
156histone arginine methylation (GO:0034969)2.41407841
157behavioral response to nicotine (GO:0035095)2.41144729
158heterochromatin organization (GO:0070828)2.40976832
159intracellular estrogen receptor signaling pathway (GO:0030520)2.39599193
160DNA conformation change (GO:0071103)2.38513551
161RNA localization (GO:0006403)2.38083200
162Golgi transport vesicle coating (GO:0048200)2.37644858
163COPI coating of Golgi vesicle (GO:0048205)2.37644858
164proline metabolic process (GO:0006560)2.37336227
165atrioventricular valve morphogenesis (GO:0003181)2.36627912
166mitotic G1 DNA damage checkpoint (GO:0031571)2.36407220
167ribosome biogenesis (GO:0042254)2.34303201
168tRNA methylation (GO:0030488)2.33200031
169DNA strand elongation (GO:0022616)2.32932641
170negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.28670115
171regulation of sister chromatid cohesion (GO:0007063)2.28449946
172peptidyl-lysine dimethylation (GO:0018027)2.27136008
173mRNA stabilization (GO:0048255)2.25907714
174RNA stabilization (GO:0043489)2.25907714
175maternal placenta development (GO:0001893)2.24193151
176nuclear pore complex assembly (GO:0051292)2.23659965
177regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.23598898
178negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)2.23004933
179positive regulation by host of viral transcription (GO:0043923)2.22956737
180DNA strand elongation involved in DNA replication (GO:0006271)2.22600390

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat5.94786358
2EZH2_22144423_ChIP-Seq_EOC_Human5.42507002
3* JARID2_20075857_ChIP-Seq_MESCs_Mouse3.41363283
4* JARID2_20064375_ChIP-Seq_MESCs_Mouse3.35518162
5* EZH2_27304074_Chip-Seq_ESCs_Mouse3.35297516
6STAT6_21828071_ChIP-Seq_BEAS2B_Human3.32532865
7* SUZ12_27294783_Chip-Seq_ESCs_Mouse3.29971704
8CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.26002515
9* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.97324955
10* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.97324955
11FOXM1_23109430_ChIP-Seq_U2OS_Human2.92328049
12* SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.88495736
13TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.87503372
14TP63_17297297_ChIP-ChIP_HaCaT_Human2.85337491
15* EZH2_27294783_Chip-Seq_ESCs_Mouse2.83038601
16E2F7_22180533_ChIP-Seq_HELA_Human2.75784649
17TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.74450488
18* EED_16625203_ChIP-ChIP_MESCs_Mouse2.72556242
19* SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.66666213
20TAF15_26573619_Chip-Seq_HEK293_Human2.64816576
21* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.60259499
22* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.55781403
23MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.50235379
24* CBX2_27304074_Chip-Seq_ESCs_Mouse2.47653187
25* SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.39830494
26DACH1_20351289_ChIP-Seq_MDA-MB-231_Human2.39810895
27* PHC1_16625203_ChIP-ChIP_MESCs_Mouse2.39348280
28* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.32191459
29HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.26770872
30* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.26217370
31* RNF2_27304074_Chip-Seq_ESCs_Mouse2.23540358
32GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.15316718
33MYC_18555785_ChIP-Seq_MESCs_Mouse2.10424133
34CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.08579278
35FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.05792753
36RACK7_27058665_Chip-Seq_MCF-7_Human2.00850511
37* TP53_20018659_ChIP-ChIP_R1E_Mouse1.99649622
38AR_21572438_ChIP-Seq_LNCaP_Human1.97673017
39CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.97071241
40* P68_20966046_ChIP-Seq_HELA_Human1.96413463
41* TET1_21451524_ChIP-Seq_MESCs_Mouse1.93753752
42* BMI1_23680149_ChIP-Seq_NPCS_Mouse1.92010869
43* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.91374933
44* RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.89001854
45* RING1B_27294783_Chip-Seq_ESCs_Mouse1.86328317
46MYC_18358816_ChIP-ChIP_MESCs_Mouse1.85098611
47EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.81985297
48PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.80873784
49ESR1_15608294_ChIP-ChIP_MCF-7_Human1.79760861
50* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.79703300
51SRY_22984422_ChIP-ChIP_TESTIS_Rat1.74631603
52HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.74325536
53TP63_19390658_ChIP-ChIP_HaCaT_Human1.72532796
54REST_21632747_ChIP-Seq_MESCs_Mouse1.71330349
55GBX2_23144817_ChIP-Seq_PC3_Human1.69807347
56ZNF263_19887448_ChIP-Seq_K562_Human1.65618006
57NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.64304886
58DNAJC2_21179169_ChIP-ChIP_NT2_Human1.61989524
59JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.61117238
60TRIM28_21343339_ChIP-Seq_HEK293_Human1.60312810
61KDM5A_27292631_Chip-Seq_BREAST_Human1.60276923
62DROSHA_22980978_ChIP-Seq_HELA_Human1.60159004
63* LXR_22292898_ChIP-Seq_THP-1_Human1.58730697
64VDR_22108803_ChIP-Seq_LS180_Human1.55417886
65ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.54481715
66ELK3_25401928_ChIP-Seq_HUVEC_Human1.54124216
67PKCTHETA_26484144_Chip-Seq_BREAST_Human1.52474408
68MYC_19079543_ChIP-ChIP_MESCs_Mouse1.51185088
69POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.50049621
70SMC4_20622854_ChIP-Seq_HELA_Human1.48939812
71* KDM2B_26808549_Chip-Seq_DND41_Human1.48594228
72* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.48360531
73* GABP_19822575_ChIP-Seq_HepG2_Human1.47348965
74MYC_19030024_ChIP-ChIP_MESCs_Mouse1.47298119
75* RNF2_27304074_Chip-Seq_NSC_Mouse1.46255346
76THAP11_20581084_ChIP-Seq_MESCs_Mouse1.46235555
77REST_18959480_ChIP-ChIP_MESCs_Mouse1.44717261
78ELF1_20517297_ChIP-Seq_JURKAT_Human1.44239725
79DCP1A_22483619_ChIP-Seq_HELA_Human1.43163159
80VDR_21846776_ChIP-Seq_THP-1_Human1.42198919
81* FOXP1_21924763_ChIP-Seq_HESCs_Human1.41474929
82* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.37338361
83EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.37087634
84CTBP1_25329375_ChIP-Seq_LNCAP_Human1.36039938
85CREB1_26743006_Chip-Seq_LNCaP_Human1.35796639
86ETS1_20019798_ChIP-Seq_JURKAT_Human1.33862976
87KLF4_18555785_ChIP-Seq_MESCs_Mouse1.32892779
88* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.32815920
89ZFX_18555785_ChIP-Seq_MESCs_Mouse1.32606029
90ERG_21242973_ChIP-ChIP_JURKAT_Human1.31657415
91* ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.31363744
92OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.30180181
93* CTCF_27219007_Chip-Seq_ERYTHROID_Human1.26938693
94* PHF8_20622854_ChIP-Seq_HELA_Human1.25738793
95* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.25027809
96* POU5F1_16153702_ChIP-ChIP_HESCs_Human1.24988331
97* TCF7_22412390_ChIP-Seq_EML_Mouse1.24761345
98KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.23562376
99* SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.22013566
100ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.21512019
101CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.20554507
102BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.20027345
103CTCF_18555785_ChIP-Seq_MESCs_Mouse1.19846373
104SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.19356433
105DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.19311654
106ELK1_22589737_ChIP-Seq_MCF10A_Human1.19180622
107RARA_24833708_ChIP-Seq_LIVER_Mouse1.19141966
108HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.19112984
109PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.19063164
110ZNF274_21170338_ChIP-Seq_K562_Hela1.18910867
111RARG_19884340_ChIP-ChIP_MEFs_Mouse1.17327555
112CTCF_21964334_Chip-Seq_Bcells_Human1.16297949
113CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.16176302
114* E2F1_20622854_ChIP-Seq_HELA_Human1.16038767
115NELFA_20434984_ChIP-Seq_ESCs_Mouse1.15795079
116MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.15459380
117* RUNX1_27514584_Chip-Seq_MCF-7_Human1.15406079
118* BCOR_27268052_Chip-Seq_Bcells_Human1.15178944
119IRF1_19129219_ChIP-ChIP_H3396_Human1.14254713
120THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.13572602
121MYCN_18555785_ChIP-Seq_MESCs_Mouse1.13535394
122YY1_21170310_ChIP-Seq_MESCs_Mouse1.13512626
123CTBP2_25329375_ChIP-Seq_LNCAP_Human1.13429510
124* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.13429134
125IKZF1_21737484_ChIP-ChIP_HCT116_Human1.13298786
126* SOX3_22085726_ChIP-Seq_NPCs_Mouse1.12949264
127* RING1B_27294783_Chip-Seq_NPCs_Mouse1.12268985
128TP53_22127205_ChIP-Seq_IMR90_Human1.11883100
129BCL6_27268052_Chip-Seq_Bcells_Human1.09744479
130ELF1_17652178_ChIP-ChIP_JURKAT_Human1.09304918
131MAF_26560356_Chip-Seq_TH2_Human1.09043328
132TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.07658857
133E2F1_21310950_ChIP-Seq_MCF-7_Human1.07282391
134ESR2_21235772_ChIP-Seq_MCF-7_Human1.07031836
135SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.07018334
136* ATF3_27146783_Chip-Seq_COLON_Human1.06754666
137PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.06127066
138* KDM2B_26808549_Chip-Seq_JURKAT_Human1.06042941
139ZFP57_27257070_Chip-Seq_ESCs_Mouse1.05179222
140CHD1_26751641_Chip-Seq_LNCaP_Human1.04466162
141HIF1A_21447827_ChIP-Seq_MCF-7_Human1.04136260
142SCL_19346495_ChIP-Seq_HPC-7_Human1.02876080
143LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.01583783
144UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.98935756
145CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.98077039
146* MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.96976211
147TTF2_22483619_ChIP-Seq_HELA_Human0.95321956
148CTCF_27219007_Chip-Seq_Bcells_Human0.94995205
149VDR_24763502_ChIP-Seq_THP-1_Human0.94197445
150ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.92774983
151CIITA_25753668_ChIP-Seq_RAJI_Human0.89028589
152ETV2_25802403_ChIP-Seq_MESCs_Mouse0.88139099
153* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.87227633
154* KDM2B_26808549_Chip-Seq_K562_Human0.82593433
155CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.80896321
156RARB_27405468_Chip-Seq_BRAIN_Mouse0.80836593
157* KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.80633300
158PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.80622040
159RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.79937872
160* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.79033930
161SA1_27219007_Chip-Seq_ERYTHROID_Human0.78975268
162TP53_18474530_ChIP-ChIP_U2OS_Human0.78505457
163* ZFP281_18757296_ChIP-ChIP_E14_Mouse0.77596156
164NOTCH1_21737748_ChIP-Seq_TLL_Human0.75362621
165XRN2_22483619_ChIP-Seq_HELA_Human0.74936291
166MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.74818638
167NR3C1_23031785_ChIP-Seq_PC12_Mouse0.74666940
168BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.74635928
169MYC_22102868_ChIP-Seq_BL_Human0.74609028
170FUS_26573619_Chip-Seq_HEK293_Human0.73625156
171SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.73552976
172SOX3_22085726_ChIP-Seq_MUSCLE_Mouse0.72943011
173HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.71840666

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation6.85029146
2MP0004381_abnormal_hair_follicle5.75691963
3MP0003880_abnormal_central_pattern3.65652800
4MP0005423_abnormal_somatic_nervous3.26539326
5MP0005409_darkened_coat_color3.21486217
6MP0003011_delayed_dark_adaptation3.03365944
7MP0003941_abnormal_skin_development2.76338961
8MP0005076_abnormal_cell_differentiation2.61182351
9MP0008789_abnormal_olfactory_epithelium2.60767748
10MP0003693_abnormal_embryo_hatching2.59135043
11MP0002282_abnormal_trachea_morphology2.58163035
12MP0000566_synostosis2.56565130
13MP0010030_abnormal_orbit_morphology2.47597450
14MP0002822_catalepsy2.27966907
15MP0001188_hyperpigmentation2.27614103
16MP0000537_abnormal_urethra_morphology2.18078248
17MP0005075_abnormal_melanosome_morpholog2.15770857
18MP0004233_abnormal_muscle_weight2.10540428
19MP0003111_abnormal_nucleus_morphology2.06889372
20MP0003938_abnormal_ear_development2.02521128
21MP0002102_abnormal_ear_morphology1.96885906
22MP0005499_abnormal_olfactory_system1.96582711
23MP0005394_taste/olfaction_phenotype1.96582711
24MP0003077_abnormal_cell_cycle1.95604480
25MP0003942_abnormal_urinary_system1.94333283
26MP0009384_cardiac_valve_regurgitation1.87897348
27MP0003705_abnormal_hypodermis_morpholog1.86483975
28MP0002234_abnormal_pharynx_morphology1.82035962
29MP0002184_abnormal_innervation1.81789488
30MP0003315_abnormal_perineum_morphology1.79358777
31MP0010094_abnormal_chromosome_stability1.73459618
32MP0003303_peritoneal_inflammation1.73282516
33MP0006072_abnormal_retinal_apoptosis1.69470677
34MP0000678_abnormal_parathyroid_gland1.68200074
35MP0005503_abnormal_tendon_morphology1.65408261
36MP0000534_abnormal_ureter_morphology1.61254981
37MP0004858_abnormal_nervous_system1.59946208
38MP0001984_abnormal_olfaction1.57344210
39MP0000467_abnormal_esophagus_morphology1.57047163
40MP0006276_abnormal_autonomic_nervous1.53621424
41MP0005174_abnormal_tail_pigmentation1.53480328
42MP0001486_abnormal_startle_reflex1.50292701
43MP0003123_paternal_imprinting1.50023185
44MP0002163_abnormal_gland_morphology1.48245347
45MP0005360_urolithiasis1.48200010
46MP0004957_abnormal_blastocyst_morpholog1.48180582
47MP0003136_yellow_coat_color1.46577700
48MP0002092_abnormal_eye_morphology1.45014035
49MP0002098_abnormal_vibrissa_morphology1.44724223
50MP0005551_abnormal_eye_electrophysiolog1.43823330
51MP0003635_abnormal_synaptic_transmissio1.43733693
52MP0002557_abnormal_social/conspecific_i1.42769782
53MP0000049_abnormal_middle_ear1.41177945
54MP0003115_abnormal_respiratory_system1.41132188
55MP0001968_abnormal_touch/_nociception1.40993647
56MP0008875_abnormal_xenobiotic_pharmacok1.40644293
57MP0002160_abnormal_reproductive_system1.39986977
58MP0002249_abnormal_larynx_morphology1.37146469
59MP0008932_abnormal_embryonic_tissue1.33785725
60MP0005410_abnormal_fertilization1.33116167
61MP0000778_abnormal_nervous_system1.29653953
62MP0005379_endocrine/exocrine_gland_phen1.27989930
63MP0002009_preneoplasia1.26531392
64MP0000465_gastrointestinal_hemorrhage1.25932805
65MP0002697_abnormal_eye_size1.25468741
66MP0005257_abnormal_intraocular_pressure1.25321951
67MP0001348_abnormal_lacrimal_gland1.25130036
68MP0001346_abnormal_lacrimal_gland1.25030320
69MP0009745_abnormal_behavioral_response1.24705050
70MP0002116_abnormal_craniofacial_bone1.21990979
71MP0003861_abnormal_nervous_system1.20887228
72MP0002272_abnormal_nervous_system1.20502962
73MP0009278_abnormal_bone_marrow1.19943758
74MP0000955_abnormal_spinal_cord1.16305239
75MP0002751_abnormal_autonomic_nervous1.15236639
76MP0000733_abnormal_muscle_development1.14981700
77MP0004185_abnormal_adipocyte_glucose1.14866859
78MP0005646_abnormal_pituitary_gland1.14471425
79MP0005365_abnormal_bile_salt1.13851070
80MP0005171_absent_coat_pigmentation1.13186067
81MP0002085_abnormal_embryonic_tissue1.12175245
82MP0002736_abnormal_nociception_after1.11975455
83MP0002653_abnormal_ependyma_morphology1.10542927
84MP0000350_abnormal_cell_proliferation1.10088918
85MP0005248_abnormal_Harderian_gland1.10048681
86MP0000631_abnormal_neuroendocrine_gland1.09631597
87MP0000003_abnormal_adipose_tissue1.08987725
88MP0000372_irregular_coat_pigmentation1.07386014
89MP0004859_abnormal_synaptic_plasticity1.06232113
90MP0002752_abnormal_somatic_nervous1.06155726
91MP0001529_abnormal_vocalization1.06013498
92MP0001672_abnormal_embryogenesis/_devel1.05346764
93MP0005380_embryogenesis_phenotype1.05346764
94MP0002080_prenatal_lethality1.04046714
95MP0005083_abnormal_biliary_tract1.03645034
96MP0002572_abnormal_emotion/affect_behav1.02405878
97MP0004197_abnormal_fetal_growth/weight/1.01692957
98MP0001919_abnormal_reproductive_system1.01188260
99MP0003937_abnormal_limbs/digits/tail_de1.00929313
100MP0002210_abnormal_sex_determination1.00734556
101MP0003959_abnormal_lean_body1.00623187
102MP0005084_abnormal_gallbladder_morpholo1.00425045
103MP0002084_abnormal_developmental_patter1.00293679
104MP0002111_abnormal_tail_morphology0.99683586
105MP0009053_abnormal_anal_canal0.99518048
106MP0003724_increased_susceptibility_to0.99258170
107MP0002132_abnormal_respiratory_system0.98547432
108MP0003385_abnormal_body_wall0.97805524
109MP0003984_embryonic_growth_retardation0.97267380
110MP0002064_seizures0.96949151
111MP0008058_abnormal_DNA_repair0.96796889
112MP0002733_abnormal_thermal_nociception0.96432931
113MP0005501_abnormal_skin_physiology0.96222836
114MP0001697_abnormal_embryo_size0.95272307
115MP0005645_abnormal_hypothalamus_physiol0.94504751
116MP0003329_amyloid_beta_deposits0.93969476
117MP0001958_emphysema0.93654279
118MP0002063_abnormal_learning/memory/cond0.93496669
119MP0002177_abnormal_outer_ear0.92996148
120MP0003698_abnormal_male_reproductive0.92297157
121MP0002882_abnormal_neuron_morphology0.91864405
122MP0003283_abnormal_digestive_organ0.91459555
123MP0001929_abnormal_gametogenesis0.91429930
124MP0002088_abnormal_embryonic_growth/wei0.91428413
125MP0000377_abnormal_hair_follicle0.89259657
126MP0000026_abnormal_inner_ear0.89038672
127MP0009250_abnormal_appendicular_skeleto0.88132922
128MP0002796_impaired_skin_barrier0.87184285
129MP0002928_abnormal_bile_duct0.86991867
130MP0002067_abnormal_sensory_capabilities0.86959105
131MP0003755_abnormal_palate_morphology0.86175904
132MP0005623_abnormal_meninges_morphology0.86105910
133MP0002735_abnormal_chemical_nociception0.85698175
134MP0005220_abnormal_exocrine_pancreas0.85684208
135MP0002233_abnormal_nose_morphology0.84682804
136MP0002114_abnormal_axial_skeleton0.83980701
137MP0005197_abnormal_uvea_morphology0.82881856
138MP0001730_embryonic_growth_arrest0.82607791
139MP0002161_abnormal_fertility/fecundity0.82519788
140MP0004811_abnormal_neuron_physiology0.82199602
141MP0004264_abnormal_extraembryonic_tissu0.81077498
142MP0001145_abnormal_male_reproductive0.80902075
143MP0003935_abnormal_craniofacial_develop0.80480829
144MP0002909_abnormal_adrenal_gland0.80470420
145MP0004742_abnormal_vestibular_system0.80236337
146MP0002081_perinatal_lethality0.80213103
147MP0000516_abnormal_urinary_system0.80013489
148MP0005367_renal/urinary_system_phenotyp0.80013489
149MP0000538_abnormal_urinary_bladder0.79573317
150MP0001270_distended_abdomen0.79486890
151MP0001944_abnormal_pancreas_morphology0.78912960
152MP0002877_abnormal_melanocyte_morpholog0.77470810
153MP0001970_abnormal_pain_threshold0.77377798
154MP0001293_anophthalmia0.76698414
155MP0005253_abnormal_eye_physiology0.75641674
156MP0002152_abnormal_brain_morphology0.75501987
157MP0005391_vision/eye_phenotype0.73078197
158MP0008569_lethality_at_weaning0.72264575
159MP0006292_abnormal_olfactory_placode0.71418669
160MP0005451_abnormal_body_composition0.70492288
161MP0002932_abnormal_joint_morphology0.70412964
162MP0001286_abnormal_eye_development0.70313900
163MP0000762_abnormal_tongue_morphology0.70005028
164MP0005195_abnormal_posterior_eye0.69021814
165MP0001986_abnormal_taste_sensitivity0.68553840
166MP0002938_white_spotting0.68419454
167MP0002638_abnormal_pupillary_reflex0.67719709
168MP0000427_abnormal_hair_cycle0.67234637
169MP0002734_abnormal_mechanical_nocicepti0.65642827
170MP0001661_extended_life_span0.65492604
171MP0002089_abnormal_postnatal_growth/wei0.65108371
172MP0001340_abnormal_eyelid_morphology0.64812444

Predicted human phenotypes

RankGene SetZ-score
1Reticulocytopenia (HP:0001896)4.94982246
2Abnormality of cells of the erythroid lineage (HP:0012130)4.56583797
3Abnormal number of erythroid precursors (HP:0012131)4.05224225
4Large eyes (HP:0001090)4.04884899
5Dry hair (HP:0011359)3.96311610
6Congenital, generalized hypertrichosis (HP:0004540)3.86919370
7Concave nail (HP:0001598)3.83290390
8Natal tooth (HP:0000695)3.82487831
9Macrocytic anemia (HP:0001972)3.77603889
10Sparse lateral eyebrow (HP:0005338)3.37815446
11Congenital sensorineural hearing impairment (HP:0008527)3.36952123
12Pallor (HP:0000980)3.32387175
13Morphological abnormality of the middle ear (HP:0008609)3.32342701
14Obstructive sleep apnea (HP:0002870)3.31312923
15Abnormality of secondary sexual hair (HP:0009888)3.20797487
16Abnormality of the axillary hair (HP:0100134)3.20797487
17Reduced subcutaneous adipose tissue (HP:0003758)3.19803261
18Humeroradial synostosis (HP:0003041)3.16284966
19Synostosis involving the elbow (HP:0003938)3.16284966
20Severe visual impairment (HP:0001141)3.05774846
21Broad face (HP:0000283)2.96562305
22Ulnar bowing (HP:0003031)2.93641658
23Hyperacusis (HP:0010780)2.91174225
24Peripheral hypomyelination (HP:0007182)2.89750764
25Rib fusion (HP:0000902)2.89672244
26Hyperthyroidism (HP:0000836)2.88938979
27Abnormal hemoglobin (HP:0011902)2.84029845
28Hypoplastic pelvis (HP:0008839)2.79339940
29Asymmetry of the thorax (HP:0001555)2.77262426
30Esotropia (HP:0000565)2.77069267
31High anterior hairline (HP:0009890)2.74775142
32Breast hypoplasia (HP:0003187)2.70898997
33Increased hepatocellular lipid droplets (HP:0006565)2.70666067
34Facial hemangioma (HP:0000329)2.69659193
35J-shaped sella turcica (HP:0002680)2.68180513
36Abnormality of oral frenula (HP:0000190)2.66654510
37Abnormality of the phalanges of the hallux (HP:0010057)2.66277166
38Progressive muscle weakness (HP:0003323)2.64080488
39Oligodactyly (hands) (HP:0001180)2.63445798
4011 pairs of ribs (HP:0000878)2.55114273
41Menorrhagia (HP:0000132)2.52300559
42Down-sloping shoulders (HP:0200021)2.50026125
43Squamous cell carcinoma (HP:0002860)2.47628928
44Microvesicular hepatic steatosis (HP:0001414)2.46321375
45Lipid accumulation in hepatocytes (HP:0006561)2.46079907
46Septate vagina (HP:0001153)2.43939203
47Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.42029921
48Broad distal phalanx of finger (HP:0009836)2.38525562
49Truncus arteriosus (HP:0001660)2.37521989
50Depressed nasal ridge (HP:0000457)2.37295032
51Abnormality of the distal phalanx of the thumb (HP:0009617)2.35553414
52Esophageal neoplasm (HP:0100751)2.35537183
53Neoplasm of head and neck (HP:0012288)2.35537183
54Acute necrotizing encephalopathy (HP:0006965)2.34935096
55Decreased activity of mitochondrial respiratory chain (HP:0008972)2.32592685
56Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.32592685
57Achilles tendon contracture (HP:0001771)2.31108157
58Abnormality of the aortic arch (HP:0012303)2.29738026
59Optic disc pallor (HP:0000543)2.29387794
60Patellar aplasia (HP:0006443)2.29276033
61Abnormality of nail color (HP:0100643)2.27992071
62Deep palmar crease (HP:0006191)2.27668911
63Aplasia/Hypoplasia of the sacrum (HP:0008517)2.26350905
64Retinal dysplasia (HP:0007973)2.26153466
65Poikiloderma (HP:0001029)2.23978503
66Epidermoid cyst (HP:0200040)2.23681348
67Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.21880791
68Aplasia/Hypoplasia of the patella (HP:0006498)2.21358338
69Testicular atrophy (HP:0000029)2.19929172
70Advanced eruption of teeth (HP:0006288)2.18084193
71Long palpebral fissure (HP:0000637)2.17893296
72Hypercortisolism (HP:0001578)2.17784047
73Amblyopia (HP:0000646)2.17514907
74Cerebellar dysplasia (HP:0007033)2.17514670
75Hyperphosphaturia (HP:0003109)2.15390993
76Patellar dislocation (HP:0002999)2.15365617
77Mitochondrial inheritance (HP:0001427)2.14573793
78Abnormality of eosinophils (HP:0001879)2.13592007
79Prolonged partial thromboplastin time (HP:0003645)2.12084471
80Chin dimple (HP:0010751)2.11400507
81Thin bony cortex (HP:0002753)2.10879157
82Short thumb (HP:0009778)2.09862608
83Prolonged bleeding time (HP:0003010)2.09694108
84Renal Fanconi syndrome (HP:0001994)2.08398610
85Short chin (HP:0000331)2.08022738
86Lip pit (HP:0100267)2.07142952
87Missing ribs (HP:0000921)2.03770949
88Brittle hair (HP:0002299)2.02376883
89Thin ribs (HP:0000883)2.01821271
90Intestinal fistula (HP:0100819)2.01749506
91Purpura (HP:0000979)2.00801838
92Acute encephalopathy (HP:0006846)2.00203907
93Abnormal mitochondria in muscle tissue (HP:0008316)1.99652254
94Abnormality of aromatic amino acid family metabolism (HP:0004338)1.99650272
95Absent epiphyses (HP:0010577)1.98897547
96Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.98897547
973-Methylglutaconic aciduria (HP:0003535)1.98866799
98Annular pancreas (HP:0001734)1.98369161
99White forelock (HP:0002211)1.97783364
100Slender long bone (HP:0003100)1.97196641
101Abnormality of the Achilles tendon (HP:0005109)1.97163238
102Proximal placement of thumb (HP:0009623)1.94533835
103Spinal canal stenosis (HP:0003416)1.94482650
104Germ cell neoplasia (HP:0100728)1.93003399
105Absent thumb (HP:0009777)1.92863520
106Absent rod-and cone-mediated responses on ERG (HP:0007688)1.92753394
107Atelectasis (HP:0100750)1.91406144
108Abnormality of the columella (HP:0009929)1.91159367
109Agitation (HP:0000713)1.90585635
110Exostoses (HP:0100777)1.90446787
111Hypoparathyroidism (HP:0000829)1.90116888
112Pterygium (HP:0001059)1.89609002
113Aplasia of the musculature (HP:0100854)1.88557616
114Turricephaly (HP:0000262)1.88555582
115Anosmia (HP:0000458)1.88545556
116Conical tooth (HP:0000698)1.88098233
117Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.87548318
118Deviation of the thumb (HP:0009603)1.86951886
119Bowel incontinence (HP:0002607)1.86838070
120Progressive macrocephaly (HP:0004481)1.86042796
121Petechiae (HP:0000967)1.85860893
122Spina bifida occulta (HP:0003298)1.85661594
123Insomnia (HP:0100785)1.84833149
124Aplasia/Hypoplasia of the clavicles (HP:0006710)1.84389911
125Abnormal number of incisors (HP:0011064)1.83363671
126Increased mean platelet volume (HP:0011877)1.83091493
127Ketoacidosis (HP:0001993)1.82349297
128Delayed myelination (HP:0012448)1.81989997
129Heterochromia iridis (HP:0001100)1.80869290
130Abnormal platelet volume (HP:0011876)1.80636645
131Premature rupture of membranes (HP:0001788)1.80577569
132Horseshoe kidney (HP:0000085)1.80280737
133Drooling (HP:0002307)1.80267422
134Excessive salivation (HP:0003781)1.80267422
135Hypoplasia of the capital femoral epiphysis (HP:0003090)1.80257803
136Abnormality of the 4th metacarpal (HP:0010012)1.77738745
137Anencephaly (HP:0002323)1.77566574
138Glossoptosis (HP:0000162)1.77187834
139Disproportionate tall stature (HP:0001519)1.77185520
140Insidious onset (HP:0003587)1.76862299
141Termporal pattern (HP:0011008)1.76862299
142Oligodactyly (HP:0012165)1.76505112
143Blue irides (HP:0000635)1.76463933
144Aplasia/Hypoplasia of the brainstem (HP:0007362)1.75577761
145Hypoplasia of the brainstem (HP:0002365)1.75577761
146Ankyloglossia (HP:0010296)1.74993370
147Vaginal fistula (HP:0004320)1.74316990
148Abnormality of DNA repair (HP:0003254)1.73925099
149Split foot (HP:0001839)1.73584221
150Visual hallucinations (HP:0002367)1.73196953
151Renal dysplasia (HP:0000110)1.73008219
152Hemorrhage of the eye (HP:0011885)1.72812692
153Woolly hair (HP:0002224)1.71275729
154Self-mutilation (HP:0000742)1.70747595
155Nasal polyposis (HP:0100582)1.70645061
156Renal duplication (HP:0000075)1.70257022
157Increased intramyocellular lipid droplets (HP:0012240)1.69986453
158Abnormal large intestine physiology (HP:0012700)1.69411424
159Sleep apnea (HP:0010535)1.69345070
160Anal stenosis (HP:0002025)1.68453760
161Abnormal sex determination (HP:0012244)1.67634108
162Sex reversal (HP:0012245)1.67634108
163Bowed forearm bones (HP:0003956)1.67491364
164Bowing of the arm (HP:0006488)1.67491364
165Abnormality of the distal phalanges of the toes (HP:0010182)1.67473104
166Ragged-red muscle fibers (HP:0003200)1.67442712
167Abnormality of the nasal septum (HP:0000419)1.67057140
168Congenital stationary night blindness (HP:0007642)1.66558272
169Double outlet right ventricle (HP:0001719)1.66399338
170Congenital malformation of the right heart (HP:0011723)1.66399338
171Ridged nail (HP:0001807)1.66253681
172Pointed chin (HP:0000307)1.66076144
173Increased CSF lactate (HP:0002490)1.65809001
174Papilloma (HP:0012740)1.64980835
175Verrucae (HP:0200043)1.64980835
176Flattened epiphyses (HP:0003071)1.64795436
177Elfin facies (HP:0004428)1.64451482
178Flat acetabular roof (HP:0003180)1.64299474
179Preauricular pit (HP:0004467)1.62335726
180Periauricular skin pits (HP:0100277)1.62335726
181Bony spicule pigmentary retinopathy (HP:0007737)1.61237594
182Hypokinesia (HP:0002375)1.60506093
183Abnormality of the radial head (HP:0003995)1.59421420
184Abnormality of the umbilical cord (HP:0010881)1.58815657
185Chromosomal breakage induced by crosslinking agents (HP:0003221)1.58366361
186Shawl scrotum (HP:0000049)1.58196932
187Abnormality of the parietal bone (HP:0002696)1.57159935
188Single umbilical artery (HP:0001195)1.56889154
189Abnormality of the fetal cardiovascular system (HP:0010948)1.56889154

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPK156.35089938
2CASK4.80830462
3TRIB34.45228102
4SIK23.14058434
5SMG12.63999512
6PRKD32.62424640
7NTRK32.37933342
8CDK122.30801536
9FES2.29582173
10MARK12.27453920
11NME22.23890244
12ICK2.17325090
13EPHA22.14268081
14PKN22.07265975
15SIK32.01788999
16MAP4K11.89184411
17DYRK21.88122973
18TNIK1.85414646
19WNK41.64501374
20SIK11.63649158
21IRAK31.58589465
22RPS6KB21.58529783
23NTRK21.54514874
24DYRK31.50938563
25CDK71.46718402
26INSRR1.41579214
27MTOR1.39937487
28PDGFRA1.37918877
29VRK11.37122923
30EEF2K1.35480539
31AURKA1.35233574
32CDC71.34535431
33SRPK11.33898045
34MAP2K71.33355293
35TESK21.30732024
36TAOK31.28577567
37MAP3K91.27707241
38LATS21.26750015
39CDK191.24353253
40CHEK21.22602330
41STK161.17656342
42CAMK1D1.16301799
43MAP2K21.15772814
44BTK1.13333838
45CSNK1G31.13229143
46EPHB21.13142737
47PHKG11.12794205
48PHKG21.12794205
49ILK1.11133286
50WEE11.10841916
51MST41.08694526
52FGFR41.08216377
53UHMK11.05805518
54IRAK21.02688373
55PNCK1.02183176
56DYRK1B1.01817037
57HIPK21.01116467
58CSNK1A1L1.00480929
59MAPK131.00305224
60TESK10.97375063
61MAPK40.96623345
62MAP3K100.95665245
63CAMK1G0.95480538
64BCKDK0.94064881
65CSNK1G10.93635755
66ITK0.92851229
67TGFBR10.92028264
68CAMK10.90922326
69MARK20.90903287
70BUB10.90218247
71MAPK110.86795999
72CDK40.84591186
73PAK20.84454471
74DYRK1A0.83017939
75BRD40.82564888
76SYK0.79963553
77ERBB30.74839558
78CCNB10.73649614
79MAP3K20.73419434
80AKT30.73208086
81ADRBK20.72141018
82CSNK1G20.71903059
83LMTK20.71464414
84VRK20.71381711
85GRK60.69110836
86PRPF4B0.69096946
87TTK0.68571763
88AURKB0.66780877
89KIT0.66682088
90RET0.66011129
91MAPKAPK30.64891612
92ATR0.64824459
93STK380.64441279
94PRKCI0.63841716
95BRAF0.62523687
96CHEK10.62309751
97CDK20.61674199
98PIM20.61493430
99CSF1R0.60530471
100STK390.60187366
101RPS6KA10.60112178
102AKT20.59997254
103TLK10.59937313
104MUSK0.59404328
105STK110.59359523
106CDK10.58342906
107RPS6KA20.57991676
108PASK0.57569963
109NEK20.56881369
110PBK0.56543322
111MST1R0.55825560
112TEC0.55742674
113MAP3K110.55553256
114PRKD20.55535866
115MAPKAPK50.55512371
116CDK90.54675117
117RPS6KC10.54036624
118RPS6KL10.54036624
119SCYL20.53645994
120BRSK10.52060990
121MET0.50736300
122TYRO30.50229790
123MAPK90.49000763
124ACVR1B0.48986482
125PTK60.48154974
126PLK10.47993773
127PDPK10.47577565
128NTRK10.47531715
129KSR10.47282664
130ADRBK10.47172550
131RPS6KA50.46875335
132ERN10.46786090
133MAP3K80.46397740
134TXK0.46178758
135PRKCZ0.46049641
136NEK60.46013673
137CLK10.45044252
138RPS6KB10.44891192
139ARAF0.43875170
140HCK0.43659765
141ZAK0.42661082
142CDK11A0.41913781
143PRKAA10.41815056
144PKN10.41695843
145CDK50.41513670
146STK240.41385517
147PDGFRB0.41334185
148CDK30.40441315
149CDK60.39897752
150LRRK20.39772901
151PLK40.39732716
152LYN0.37663891
153MAPK120.37341511
154AKT10.36275218
155MAPK80.35990837
156DAPK30.35665657
157MINK10.34891119
158TRPM70.34664046
159PRKCQ0.33884586
160PRKCG0.33254021
161CDK80.33099483
162ZAP700.32730437
163RPS6KA60.32649454
164TSSK60.32518195
165EPHB10.30647771
166LCK0.30327519
167MAP3K10.30085371

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030107.15658185
2Oxidative phosphorylation_Homo sapiens_hsa001903.07849122
3Parkinsons disease_Homo sapiens_hsa050122.82703849
4Protein export_Homo sapiens_hsa030602.66919976
5Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.51894421
6Alzheimers disease_Homo sapiens_hsa050102.43733385
7DNA replication_Homo sapiens_hsa030302.38571704
8Nicotine addiction_Homo sapiens_hsa050332.24525995
9Base excision repair_Homo sapiens_hsa034102.24006321
10Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.21352743
11Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.16387296
12Cardiac muscle contraction_Homo sapiens_hsa042602.02285866
13Phototransduction_Homo sapiens_hsa047441.99651421
14Basal cell carcinoma_Homo sapiens_hsa052171.97475212
15Sulfur metabolism_Homo sapiens_hsa009201.95290165
16Notch signaling pathway_Homo sapiens_hsa043301.93075082
17Biosynthesis of amino acids_Homo sapiens_hsa012301.86339641
18Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.77038630
19Maturity onset diabetes of the young_Homo sapiens_hsa049501.75593673
20Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.72494876
21Cell cycle_Homo sapiens_hsa041101.64498742
22Nucleotide excision repair_Homo sapiens_hsa034201.60149651
23Olfactory transduction_Homo sapiens_hsa047401.59710849
24RNA transport_Homo sapiens_hsa030131.57327534
25Fructose and mannose metabolism_Homo sapiens_hsa000511.56279546
26Huntingtons disease_Homo sapiens_hsa050161.54080523
27Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.54019106
28Bladder cancer_Homo sapiens_hsa052191.53133982
29mTOR signaling pathway_Homo sapiens_hsa041501.50173675
30Fanconi anemia pathway_Homo sapiens_hsa034601.48883950
31Primary bile acid biosynthesis_Homo sapiens_hsa001201.47217534
32Lysine degradation_Homo sapiens_hsa003101.45176339
33Endometrial cancer_Homo sapiens_hsa052131.44726507
34Glutamatergic synapse_Homo sapiens_hsa047241.39838647
35Central carbon metabolism in cancer_Homo sapiens_hsa052301.39429521
36Taste transduction_Homo sapiens_hsa047421.38759797
37Other glycan degradation_Homo sapiens_hsa005111.38039903
38Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.35383688
39Axon guidance_Homo sapiens_hsa043601.34204413
40Butanoate metabolism_Homo sapiens_hsa006501.33308706
41Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.32260405
42Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.29208897
43Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.28957176
44Hippo signaling pathway_Homo sapiens_hsa043901.28368757
45Cocaine addiction_Homo sapiens_hsa050301.26628723
46Chronic myeloid leukemia_Homo sapiens_hsa052201.26336782
47Spliceosome_Homo sapiens_hsa030401.24986213
48Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.23813327
49Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.23649800
50Alcoholism_Homo sapiens_hsa050341.21528457
512-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.21336370
52Pyrimidine metabolism_Homo sapiens_hsa002401.20678662
53Serotonergic synapse_Homo sapiens_hsa047261.19770076
54Primary immunodeficiency_Homo sapiens_hsa053401.13734018
55Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.12226115
56Dopaminergic synapse_Homo sapiens_hsa047281.11861751
57mRNA surveillance pathway_Homo sapiens_hsa030151.10676671
58Sulfur relay system_Homo sapiens_hsa041221.09668430
59GABAergic synapse_Homo sapiens_hsa047271.08956204
60AMPK signaling pathway_Homo sapiens_hsa041521.08855463
61Pentose phosphate pathway_Homo sapiens_hsa000301.06378275
62Mismatch repair_Homo sapiens_hsa034301.05318727
63Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.04756997
64Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.03526301
65Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.02065873
66Longevity regulating pathway - mammal_Homo sapiens_hsa042111.02046724
67Oxytocin signaling pathway_Homo sapiens_hsa049211.01703570
68Amphetamine addiction_Homo sapiens_hsa050311.00730334
69Thyroid cancer_Homo sapiens_hsa052161.00159959
70Morphine addiction_Homo sapiens_hsa050321.00152038
71Arginine biosynthesis_Homo sapiens_hsa002200.98346838
72RNA polymerase_Homo sapiens_hsa030200.97074806
73Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.95816454
74Thyroid hormone signaling pathway_Homo sapiens_hsa049190.95114080
75Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.94796704
76Gap junction_Homo sapiens_hsa045400.94674204
77Renin secretion_Homo sapiens_hsa049240.93984815
78T cell receptor signaling pathway_Homo sapiens_hsa046600.93675764
79Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.93093582
80Retinol metabolism_Homo sapiens_hsa008300.90950683
81Steroid biosynthesis_Homo sapiens_hsa001000.90742920
82Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.90344106
83Insulin signaling pathway_Homo sapiens_hsa049100.89542005
84Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.89178131
85Vitamin B6 metabolism_Homo sapiens_hsa007500.88362881
86Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.88201565
87One carbon pool by folate_Homo sapiens_hsa006700.85567059
88VEGF signaling pathway_Homo sapiens_hsa043700.85034406
89MicroRNAs in cancer_Homo sapiens_hsa052060.83645731
90Prostate cancer_Homo sapiens_hsa052150.83433014
91Cyanoamino acid metabolism_Homo sapiens_hsa004600.82412420
92GnRH signaling pathway_Homo sapiens_hsa049120.81866169
93Fatty acid biosynthesis_Homo sapiens_hsa000610.80927145
94Circadian entrainment_Homo sapiens_hsa047130.80676061
95Systemic lupus erythematosus_Homo sapiens_hsa053220.80437867
96Acute myeloid leukemia_Homo sapiens_hsa052210.79826485
97Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.79317572
98Cholinergic synapse_Homo sapiens_hsa047250.79279177
99Carbon metabolism_Homo sapiens_hsa012000.78857509
100Viral carcinogenesis_Homo sapiens_hsa052030.78383139
101Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.77135636
102Folate biosynthesis_Homo sapiens_hsa007900.74227853
103Neurotrophin signaling pathway_Homo sapiens_hsa047220.73536332
104Aldosterone synthesis and secretion_Homo sapiens_hsa049250.73100692
105Histidine metabolism_Homo sapiens_hsa003400.71447471
106Glioma_Homo sapiens_hsa052140.70223681
107Melanoma_Homo sapiens_hsa052180.66942522
108Pancreatic cancer_Homo sapiens_hsa052120.66611297
109Wnt signaling pathway_Homo sapiens_hsa043100.66272132
110Tyrosine metabolism_Homo sapiens_hsa003500.65240873
111Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.64047873
112Estrogen signaling pathway_Homo sapiens_hsa049150.64046374
113Inositol phosphate metabolism_Homo sapiens_hsa005620.63576693
114Chemical carcinogenesis_Homo sapiens_hsa052040.63537284
115Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.63175394
116Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.62588900
117Renal cell carcinoma_Homo sapiens_hsa052110.62499854
118Homologous recombination_Homo sapiens_hsa034400.61440485
119Fatty acid elongation_Homo sapiens_hsa000620.61390825
120Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.60980334
121Insulin secretion_Homo sapiens_hsa049110.60903009
122Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.59663347
123Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.59489006
124Galactose metabolism_Homo sapiens_hsa000520.59403877
125Complement and coagulation cascades_Homo sapiens_hsa046100.58889880
126Long-term depression_Homo sapiens_hsa047300.58163614
127Glycosaminoglycan degradation_Homo sapiens_hsa005310.57985816
128B cell receptor signaling pathway_Homo sapiens_hsa046620.56571013
129SNARE interactions in vesicular transport_Homo sapiens_hsa041300.55901694
130Platelet activation_Homo sapiens_hsa046110.55070669
131Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.54820577
132Prolactin signaling pathway_Homo sapiens_hsa049170.54059562
133Small cell lung cancer_Homo sapiens_hsa052220.52555526
134Drug metabolism - other enzymes_Homo sapiens_hsa009830.51665389
135Selenocompound metabolism_Homo sapiens_hsa004500.50663627
136Basal transcription factors_Homo sapiens_hsa030220.49286809
137Prion diseases_Homo sapiens_hsa050200.49177087
138p53 signaling pathway_Homo sapiens_hsa041150.49126721
139Non-homologous end-joining_Homo sapiens_hsa034500.48588850
140Pyruvate metabolism_Homo sapiens_hsa006200.47523431
141MAPK signaling pathway_Homo sapiens_hsa040100.47149837
142Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.47078417
143Pentose and glucuronate interconversions_Homo sapiens_hsa000400.45803829
144Choline metabolism in cancer_Homo sapiens_hsa052310.45715395
145ErbB signaling pathway_Homo sapiens_hsa040120.45558511
146Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.45068734
147Dilated cardiomyopathy_Homo sapiens_hsa054140.44432885
148Arginine and proline metabolism_Homo sapiens_hsa003300.43889208
149Endocytosis_Homo sapiens_hsa041440.43342730
150Vibrio cholerae infection_Homo sapiens_hsa051100.42638144
151Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.40771645
152Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.39225019
153ABC transporters_Homo sapiens_hsa020100.39043062
154Melanogenesis_Homo sapiens_hsa049160.38542937
155N-Glycan biosynthesis_Homo sapiens_hsa005100.38104300
156Sphingolipid metabolism_Homo sapiens_hsa006000.37783428
157beta-Alanine metabolism_Homo sapiens_hsa004100.37691643
158Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.36808693
159Hedgehog signaling pathway_Homo sapiens_hsa043400.36417821
160Ras signaling pathway_Homo sapiens_hsa040140.33489177
161Arachidonic acid metabolism_Homo sapiens_hsa005900.32516908
162Hematopoietic cell lineage_Homo sapiens_hsa046400.30201930
163Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.29912932
164Colorectal cancer_Homo sapiens_hsa052100.29023357
165Salivary secretion_Homo sapiens_hsa049700.28333794
166Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.27931115
167Non-small cell lung cancer_Homo sapiens_hsa052230.27729439
168Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.27409417
169Linoleic acid metabolism_Homo sapiens_hsa005910.25555480
170Phenylalanine metabolism_Homo sapiens_hsa003600.23470348

Most similar genes based on co-expression Upload to Enrichr

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