Rank | Gene Set | Z-score |
---|---|---|
1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.59646872 |
2 | ATP synthesis coupled proton transport (GO:0015986) | 5.38173627 |
3 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.38173627 |
4 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.31906771 |
5 | chaperone-mediated protein transport (GO:0072321) | 4.26561699 |
6 | GTP biosynthetic process (GO:0006183) | 3.97437873 |
7 | negative regulation of microtubule polymerization (GO:0031115) | 3.95478040 |
8 | neuron cell-cell adhesion (GO:0007158) | 3.90684273 |
9 | respiratory electron transport chain (GO:0022904) | 3.90546037 |
10 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.87975308 |
11 | NADH dehydrogenase complex assembly (GO:0010257) | 3.87975308 |
12 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.87975308 |
13 | electron transport chain (GO:0022900) | 3.87482795 |
14 | regulation of cilium movement (GO:0003352) | 3.82888673 |
15 | intraciliary transport (GO:0042073) | 3.80756401 |
16 | protein complex biogenesis (GO:0070271) | 3.68250624 |
17 | protein localization to cilium (GO:0061512) | 3.65554396 |
18 | motile cilium assembly (GO:0044458) | 3.63608723 |
19 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.53743192 |
20 | UTP biosynthetic process (GO:0006228) | 3.53398838 |
21 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.39949849 |
22 | cilium movement (GO:0003341) | 3.38442931 |
23 | microtubule severing (GO:0051013) | 3.38306438 |
24 | vocalization behavior (GO:0071625) | 3.36442084 |
25 | establishment of integrated proviral latency (GO:0075713) | 3.36293106 |
26 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.33336189 |
27 | protein polyglutamylation (GO:0018095) | 3.27648697 |
28 | synaptic vesicle exocytosis (GO:0016079) | 3.24888894 |
29 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.24643440 |
30 | nonmotile primary cilium assembly (GO:0035058) | 3.22629019 |
31 | cullin deneddylation (GO:0010388) | 3.22295745 |
32 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.21927044 |
33 | epithelial cilium movement (GO:0003351) | 3.18091198 |
34 | axonemal dynein complex assembly (GO:0070286) | 3.17122000 |
35 | ATP biosynthetic process (GO:0006754) | 3.15021422 |
36 | cilium or flagellum-dependent cell motility (GO:0001539) | 3.12678800 |
37 | protein deneddylation (GO:0000338) | 3.11985264 |
38 | protein localization to synapse (GO:0035418) | 3.09061997 |
39 | protein insertion into membrane (GO:0051205) | 3.08802682 |
40 | cilium morphogenesis (GO:0060271) | 3.05941034 |
41 | protein neddylation (GO:0045116) | 3.04838771 |
42 | nucleoside diphosphate phosphorylation (GO:0006165) | 3.00368519 |
43 | negative regulation of ligase activity (GO:0051352) | 2.99410658 |
44 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.99410658 |
45 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.98672601 |
46 | L-serine metabolic process (GO:0006563) | 2.97788111 |
47 | UTP metabolic process (GO:0046051) | 2.97536951 |
48 | * cilium organization (GO:0044782) | 2.96636465 |
49 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.96563458 |
50 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.95864498 |
51 | left/right pattern formation (GO:0060972) | 2.94173838 |
52 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.93452878 |
53 | * cilium assembly (GO:0042384) | 2.93003509 |
54 | postsynaptic membrane organization (GO:0001941) | 2.86776302 |
55 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.86492514 |
56 | CTP metabolic process (GO:0046036) | 2.85347985 |
57 | CTP biosynthetic process (GO:0006241) | 2.85347985 |
58 | axoneme assembly (GO:0035082) | 2.84935900 |
59 | hydrogen ion transmembrane transport (GO:1902600) | 2.83799902 |
60 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.82698652 |
61 | histone arginine methylation (GO:0034969) | 2.81822748 |
62 | pyrimidine nucleobase catabolic process (GO:0006208) | 2.81502587 |
63 | microtubule depolymerization (GO:0007019) | 2.80757584 |
64 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 2.80079848 |
65 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.79983895 |
66 | aldehyde catabolic process (GO:0046185) | 2.75695525 |
67 | mitochondrial fragmentation involved in apoptotic process (GO:0043653) | 2.75258142 |
68 | nucleoside triphosphate biosynthetic process (GO:0009142) | 2.74721173 |
69 | 7-methylguanosine mRNA capping (GO:0006370) | 2.74299343 |
70 | oxidative phosphorylation (GO:0006119) | 2.74130313 |
71 | inner mitochondrial membrane organization (GO:0007007) | 2.71243599 |
72 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.70768008 |
73 | 7-methylguanosine RNA capping (GO:0009452) | 2.65524691 |
74 | RNA capping (GO:0036260) | 2.65524691 |
75 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.63594495 |
76 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.63209342 |
77 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.63209342 |
78 | sensory perception of smell (GO:0007608) | 2.62905925 |
79 | establishment of viral latency (GO:0019043) | 2.61865220 |
80 | regulation of microtubule-based movement (GO:0060632) | 2.61450042 |
81 | establishment of protein localization to mitochondrion (GO:0072655) | 2.60780264 |
82 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 2.60525352 |
83 | deoxyribonucleoside diphosphate metabolic process (GO:0009186) | 2.60495041 |
84 | proteasome assembly (GO:0043248) | 2.60314984 |
85 | protein targeting to mitochondrion (GO:0006626) | 2.59439069 |
86 | regulation of synapse structural plasticity (GO:0051823) | 2.59424461 |
87 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 2.59271243 |
88 | ATP hydrolysis coupled proton transport (GO:0015991) | 2.59271243 |
89 | sequestering of actin monomers (GO:0042989) | 2.58409737 |
90 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.58396941 |
91 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.58396941 |
92 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.58396941 |
93 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 2.57931167 |
94 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.57189420 |
95 | respiratory chain complex IV assembly (GO:0008535) | 2.56680131 |
96 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.55939906 |
97 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 2.55314171 |
98 | termination of RNA polymerase III transcription (GO:0006386) | 2.54861340 |
99 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.54861340 |
100 | platelet dense granule organization (GO:0060155) | 2.54686534 |
101 | maturation of SSU-rRNA (GO:0030490) | 2.54446180 |
102 | positive regulation of ligase activity (GO:0051351) | 2.52996398 |
103 | positive regulation of synapse maturation (GO:0090129) | 2.52405458 |
104 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.50560400 |
105 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.50560400 |
106 | retinal ganglion cell axon guidance (GO:0031290) | 2.50097190 |
107 | viral transcription (GO:0019083) | 2.47154762 |
108 | DNA deamination (GO:0045006) | 2.46096725 |
109 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.46083199 |
110 | spliceosomal snRNP assembly (GO:0000387) | 2.45607547 |
111 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.45602032 |
112 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.45602032 |
113 | viral mRNA export from host cell nucleus (GO:0046784) | 2.42410167 |
114 | presynaptic membrane organization (GO:0097090) | 2.41525250 |
115 | peptidyl-arginine omega-N-methylation (GO:0035247) | 2.41287670 |
116 | presynaptic membrane assembly (GO:0097105) | 2.41139704 |
117 | DNA damage response, detection of DNA damage (GO:0042769) | 2.40575684 |
118 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.40450341 |
119 | peptidyl-histidine modification (GO:0018202) | 2.40316701 |
120 | axon extension involved in axon guidance (GO:0048846) | 2.39140597 |
121 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 2.39140597 |
122 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.38369496 |
123 | regulation of mitochondrial translation (GO:0070129) | 2.36103736 |
124 | microtubule bundle formation (GO:0001578) | 2.31937820 |
125 | ubiquinone biosynthetic process (GO:0006744) | 2.31692037 |
126 | cytochrome complex assembly (GO:0017004) | 2.30134858 |
127 | ubiquinone metabolic process (GO:0006743) | 2.29936921 |
128 | smoothened signaling pathway (GO:0007224) | 2.29434140 |
129 | * cellular component assembly involved in morphogenesis (GO:0010927) | 2.29154488 |
130 | negative regulation of axon guidance (GO:1902668) | 2.28199081 |
131 | base-excision repair, AP site formation (GO:0006285) | 2.27444919 |
132 | left/right axis specification (GO:0070986) | 2.26323260 |
133 | establishment of tissue polarity (GO:0007164) | 2.25331141 |
134 | establishment of planar polarity (GO:0001736) | 2.25331141 |
135 | glutathione derivative biosynthetic process (GO:1901687) | 2.24793785 |
136 | glutathione derivative metabolic process (GO:1901685) | 2.24793785 |
137 | limb bud formation (GO:0060174) | 2.19390240 |
138 | resolution of meiotic recombination intermediates (GO:0000712) | 2.18058927 |
139 | nucleobase catabolic process (GO:0046113) | 2.18035942 |
140 | short-term memory (GO:0007614) | 2.17070594 |
141 | serine family amino acid biosynthetic process (GO:0009070) | 2.11906166 |
142 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 2.09501156 |
143 | otic vesicle formation (GO:0030916) | 2.09079558 |
144 | amino acid salvage (GO:0043102) | 2.06496489 |
145 | L-methionine salvage (GO:0071267) | 2.06496489 |
146 | L-methionine biosynthetic process (GO:0071265) | 2.06496489 |
147 | centriole replication (GO:0007099) | 2.06005607 |
148 | branched-chain amino acid catabolic process (GO:0009083) | 2.05457943 |
149 | positive regulation of mitochondrial fission (GO:0090141) | 2.04489060 |
150 | cochlea development (GO:0090102) | 2.04058703 |
151 | chromatin remodeling at centromere (GO:0031055) | 2.03867527 |
152 | serine family amino acid catabolic process (GO:0009071) | 2.03718617 |
153 | sperm motility (GO:0030317) | 2.02898123 |
154 | neuron fate determination (GO:0048664) | 2.01785772 |
155 | determination of left/right symmetry (GO:0007368) | 2.01478231 |
156 | sterol biosynthetic process (GO:0016126) | 2.00515568 |
157 | DNA integration (GO:0015074) | 1.97511501 |
158 | response to nitrosative stress (GO:0051409) | 1.96719177 |
159 | histone H2A acetylation (GO:0043968) | 1.96538310 |
160 | protein-cofactor linkage (GO:0018065) | 1.95329510 |
161 | ventricular system development (GO:0021591) | 1.95254385 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.29104541 |
2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.34486610 |
3 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.17254128 |
4 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 3.14302196 |
5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.10530514 |
6 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.97305177 |
7 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.92097944 |
8 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.86612166 |
9 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.77658318 |
10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.71070981 |
11 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.51269941 |
12 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.50478469 |
13 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.34665718 |
14 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.28034179 |
15 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.27518693 |
16 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.22138508 |
17 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.21013767 |
18 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.20584359 |
19 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.18229716 |
20 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.99675385 |
21 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.97112365 |
22 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.94792160 |
23 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.92275689 |
24 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.91735457 |
25 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.87846476 |
26 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.83790869 |
27 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.83485275 |
28 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.79631542 |
29 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.64051466 |
30 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 1.63625748 |
31 | EWS_26573619_Chip-Seq_HEK293_Human | 1.62935552 |
32 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.61347599 |
33 | * VDR_23849224_ChIP-Seq_CD4+_Human | 1.60959609 |
34 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.59845843 |
35 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.58301687 |
36 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.58273089 |
37 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.57524513 |
38 | * SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.56300443 |
39 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.55957301 |
40 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.54562324 |
41 | * GABP_19822575_ChIP-Seq_HepG2_Human | 1.53472816 |
42 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.53412478 |
43 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.53056687 |
44 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.52892091 |
45 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.52533403 |
46 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.52344807 |
47 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.48176433 |
48 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.46446609 |
49 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.45690447 |
50 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.43329240 |
51 | P300_19829295_ChIP-Seq_ESCs_Human | 1.43235460 |
52 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.41755769 |
53 | * FOXP3_21729870_ChIP-Seq_TREG_Human | 1.39109373 |
54 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.35947455 |
55 | * CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.35268812 |
56 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.34603640 |
57 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.33046382 |
58 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.32164140 |
59 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.30869307 |
60 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.30474985 |
61 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.30233453 |
62 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.25985216 |
63 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.25506456 |
64 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.23276264 |
65 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.22454522 |
66 | VDR_22108803_ChIP-Seq_LS180_Human | 1.21940768 |
67 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.21720882 |
68 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.20869078 |
69 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.19858236 |
70 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.19795555 |
71 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.19545162 |
72 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.18539741 |
73 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.16957461 |
74 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.16728697 |
75 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.13351191 |
76 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.12804951 |
77 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.12804197 |
78 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.12391925 |
79 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.11711026 |
80 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.11690880 |
81 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.08824248 |
82 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.06153430 |
83 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.06153430 |
84 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.06138869 |
85 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.05964985 |
86 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.05568893 |
87 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.04551298 |
88 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.03913830 |
89 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.03568111 |
90 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.03165863 |
91 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.02709746 |
92 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.02671970 |
93 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.02609810 |
94 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.02449664 |
95 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.02325699 |
96 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.01941394 |
97 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.01933237 |
98 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.01389807 |
99 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.00341451 |
100 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.99700046 |
101 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 0.99573720 |
102 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.99455592 |
103 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 0.99113558 |
104 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.98841103 |
105 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.98638623 |
106 | ZNF274_21170338_ChIP-Seq_K562_Hela | 0.97967350 |
107 | ELK1_19687146_ChIP-ChIP_HELA_Human | 0.97961152 |
108 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.97307508 |
109 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.96339562 |
110 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.96339562 |
111 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.96193426 |
112 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.96050134 |
113 | EOMES_21245162_ChIP-Seq_HESCs_Human | 0.95885129 |
114 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 0.95371648 |
115 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.95166595 |
116 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.95116448 |
117 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 0.94535568 |
118 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 0.94484301 |
119 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.94294149 |
120 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.94078327 |
121 | FUS_26573619_Chip-Seq_HEK293_Human | 0.92580094 |
122 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.91254452 |
123 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.90324155 |
124 | * PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.90278543 |
125 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.89728238 |
126 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.87929749 |
127 | E2F1_17053090_ChIP-ChIP_MCF-7_Human | 0.87279174 |
128 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.85698460 |
129 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 0.85689406 |
130 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.85453019 |
131 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 0.85356537 |
132 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 0.85259386 |
133 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.85053967 |
134 | AR_25329375_ChIP-Seq_VCAP_Human | 0.84824212 |
135 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.84664742 |
136 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.84514655 |
137 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.84441326 |
138 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.84188387 |
139 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 0.83093014 |
140 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.82355368 |
141 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.82299469 |
142 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.82254211 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003880_abnormal_central_pattern | 3.50687920 |
2 | MP0004859_abnormal_synaptic_plasticity | 3.39577980 |
3 | MP0001984_abnormal_olfaction | 3.12217090 |
4 | MP0008789_abnormal_olfactory_epithelium | 2.88780555 |
5 | MP0001529_abnormal_vocalization | 2.80794594 |
6 | MP0005394_taste/olfaction_phenotype | 2.62468963 |
7 | MP0005499_abnormal_olfactory_system | 2.62468963 |
8 | MP0003136_yellow_coat_color | 2.61200944 |
9 | MP0003635_abnormal_synaptic_transmissio | 2.55941081 |
10 | MP0004270_analgesia | 2.53241242 |
11 | MP0006276_abnormal_autonomic_nervous | 2.43480419 |
12 | MP0002653_abnormal_ependyma_morphology | 2.25804454 |
13 | MP0010030_abnormal_orbit_morphology | 2.19617458 |
14 | MP0002063_abnormal_learning/memory/cond | 2.11647506 |
15 | MP0001968_abnormal_touch/_nociception | 2.10849474 |
16 | MP0002102_abnormal_ear_morphology | 2.09302096 |
17 | MP0002736_abnormal_nociception_after | 2.07317912 |
18 | MP0000778_abnormal_nervous_system | 2.06427588 |
19 | MP0009745_abnormal_behavioral_response | 2.06371852 |
20 | MP0002734_abnormal_mechanical_nocicepti | 2.05627939 |
21 | MP0005423_abnormal_somatic_nervous | 2.00144343 |
22 | MP0002184_abnormal_innervation | 1.96142180 |
23 | MP0002234_abnormal_pharynx_morphology | 1.94561093 |
24 | MP0008877_abnormal_DNA_methylation | 1.93635726 |
25 | MP0002572_abnormal_emotion/affect_behav | 1.90446132 |
26 | MP0005410_abnormal_fertilization | 1.90442284 |
27 | MP0002064_seizures | 1.89458966 |
28 | MP0005645_abnormal_hypothalamus_physiol | 1.87333459 |
29 | MP0002272_abnormal_nervous_system | 1.82141829 |
30 | MP0001905_abnormal_dopamine_level | 1.80969413 |
31 | MP0005646_abnormal_pituitary_gland | 1.73010922 |
32 | MP0009046_muscle_twitch | 1.71086074 |
33 | MP0002638_abnormal_pupillary_reflex | 1.69546523 |
34 | MP0002735_abnormal_chemical_nociception | 1.69136516 |
35 | MP0001440_abnormal_grooming_behavior | 1.61504145 |
36 | MP0002233_abnormal_nose_morphology | 1.61503057 |
37 | MP0002557_abnormal_social/conspecific_i | 1.61319442 |
38 | MP0002160_abnormal_reproductive_system | 1.59704590 |
39 | MP0000566_synostosis | 1.55852063 |
40 | MP0002751_abnormal_autonomic_nervous | 1.50997430 |
41 | MP0003787_abnormal_imprinting | 1.47613013 |
42 | MP0003122_maternal_imprinting | 1.47039352 |
43 | MP0001188_hyperpigmentation | 1.46981820 |
44 | MP0006292_abnormal_olfactory_placode | 1.44665385 |
45 | MP0004811_abnormal_neuron_physiology | 1.44373948 |
46 | MP0002733_abnormal_thermal_nociception | 1.40561146 |
47 | MP0004142_abnormal_muscle_tone | 1.40423278 |
48 | MP0000631_abnormal_neuroendocrine_gland | 1.39361241 |
49 | MP0002282_abnormal_trachea_morphology | 1.38828796 |
50 | MP0001486_abnormal_startle_reflex | 1.38143127 |
51 | MP0001293_anophthalmia | 1.38073252 |
52 | MP0002067_abnormal_sensory_capabilities | 1.37276673 |
53 | MP0004133_heterotaxia | 1.36765728 |
54 | MP0002882_abnormal_neuron_morphology | 1.36623268 |
55 | MP0001970_abnormal_pain_threshold | 1.36364162 |
56 | MP0009379_abnormal_foot_pigmentation | 1.36110483 |
57 | MP0005084_abnormal_gallbladder_morpholo | 1.35891125 |
58 | MP0002837_dystrophic_cardiac_calcinosis | 1.35409150 |
59 | MP0003186_abnormal_redox_activity | 1.32779218 |
60 | MP0003937_abnormal_limbs/digits/tail_de | 1.29319836 |
61 | MP0000955_abnormal_spinal_cord | 1.29062764 |
62 | MP0003718_maternal_effect | 1.25055593 |
63 | MP0001485_abnormal_pinna_reflex | 1.24432091 |
64 | MP0003693_abnormal_embryo_hatching | 1.24099299 |
65 | MP0002752_abnormal_somatic_nervous | 1.22788370 |
66 | * MP0003698_abnormal_male_reproductive | 1.22519167 |
67 | MP0002152_abnormal_brain_morphology | 1.21584742 |
68 | MP0000372_irregular_coat_pigmentation | 1.19749638 |
69 | MP0003119_abnormal_digestive_system | 1.18613661 |
70 | MP0006072_abnormal_retinal_apoptosis | 1.17259416 |
71 | MP0003121_genomic_imprinting | 1.17257158 |
72 | MP0003879_abnormal_hair_cell | 1.15153982 |
73 | MP0003861_abnormal_nervous_system | 1.13802199 |
74 | MP0002822_catalepsy | 1.12239655 |
75 | MP0008875_abnormal_xenobiotic_pharmacok | 1.11471210 |
76 | MP0003755_abnormal_palate_morphology | 1.11270111 |
77 | MP0003011_delayed_dark_adaptation | 1.11197016 |
78 | MP0003283_abnormal_digestive_organ | 1.10581262 |
79 | MP0000516_abnormal_urinary_system | 1.05683722 |
80 | MP0005367_renal/urinary_system_phenotyp | 1.05683722 |
81 | MP0000026_abnormal_inner_ear | 1.05124891 |
82 | MP0006035_abnormal_mitochondrial_morpho | 1.04563730 |
83 | MP0002163_abnormal_gland_morphology | 1.04499955 |
84 | MP0002066_abnormal_motor_capabilities/c | 1.04301543 |
85 | MP0001986_abnormal_taste_sensitivity | 1.03578724 |
86 | MP0003315_abnormal_perineum_morphology | 1.03430950 |
87 | MP0010386_abnormal_urinary_bladder | 1.00964175 |
88 | MP0005551_abnormal_eye_electrophysiolog | 1.00879427 |
89 | MP0005386_behavior/neurological_phenoty | 1.00698372 |
90 | MP0004924_abnormal_behavior | 1.00698372 |
91 | MP0008058_abnormal_DNA_repair | 1.00601336 |
92 | MP0001299_abnormal_eye_distance/ | 0.98981739 |
93 | MP0001929_abnormal_gametogenesis | 0.97661713 |
94 | MP0000049_abnormal_middle_ear | 0.96495437 |
95 | MP0005503_abnormal_tendon_morphology | 0.94876566 |
96 | MP0004957_abnormal_blastocyst_morpholog | 0.94482335 |
97 | MP0004858_abnormal_nervous_system | 0.94408641 |
98 | MP0001963_abnormal_hearing_physiology | 0.94201429 |
99 | MP0008932_abnormal_embryonic_tissue | 0.93765893 |
100 | MP0003938_abnormal_ear_development | 0.93263255 |
101 | MP0001286_abnormal_eye_development | 0.92826384 |
102 | MP0004742_abnormal_vestibular_system | 0.92748173 |
103 | MP0003806_abnormal_nucleotide_metabolis | 0.91490033 |
104 | MP0004885_abnormal_endolymph | 0.91477039 |
105 | MP0010094_abnormal_chromosome_stability | 0.90273065 |
106 | MP0009780_abnormal_chondrocyte_physiolo | 0.90172957 |
107 | MP0002090_abnormal_vision | 0.88991030 |
108 | MP0005389_reproductive_system_phenotype | 0.88883503 |
109 | MP0002249_abnormal_larynx_morphology | 0.88493502 |
110 | MP0000751_myopathy | 0.88072044 |
111 | MP0003890_abnormal_embryonic-extraembry | 0.87741191 |
112 | MP0005391_vision/eye_phenotype | 0.86204901 |
113 | MP0000537_abnormal_urethra_morphology | 0.86170374 |
114 | MP0003942_abnormal_urinary_system | 0.85975033 |
115 | MP0005171_absent_coat_pigmentation | 0.85515861 |
116 | MP0000762_abnormal_tongue_morphology | 0.84695116 |
117 | MP0002697_abnormal_eye_size | 0.84682385 |
118 | MP0002938_white_spotting | 0.84424513 |
119 | MP0002210_abnormal_sex_determination | 0.83749281 |
120 | MP0008569_lethality_at_weaning | 0.83128392 |
121 | MP0005195_abnormal_posterior_eye | 0.82267931 |
122 | MP0005253_abnormal_eye_physiology | 0.81790824 |
123 | MP0003123_paternal_imprinting | 0.79108282 |
124 | MP0009250_abnormal_appendicular_skeleto | 0.77697694 |
125 | MP0004215_abnormal_myocardial_fiber | 0.77682090 |
126 | MP0003941_abnormal_skin_development | 0.77085010 |
127 | MP0010368_abnormal_lymphatic_system | 0.77070512 |
128 | MP0001501_abnormal_sleep_pattern | 0.76569369 |
129 | MP0002909_abnormal_adrenal_gland | 0.76315166 |
130 | MP0006036_abnormal_mitochondrial_physio | 0.75141442 |
131 | MP0005623_abnormal_meninges_morphology | 0.75025430 |
132 | MP0003077_abnormal_cell_cycle | 0.74865360 |
133 | MP0001324_abnormal_eye_pigmentation | 0.74531372 |
134 | MP0009697_abnormal_copulation | 0.74239115 |
135 | MP0003195_calcinosis | 0.74028468 |
136 | * MP0002161_abnormal_fertility/fecundity | 0.73967961 |
137 | MP0003137_abnormal_impulse_conducting | 0.73759391 |
138 | MP0009384_cardiac_valve_regurgitation | 0.72820710 |
139 | MP0002229_neurodegeneration | 0.72752760 |
140 | MP0002116_abnormal_craniofacial_bone | 0.72423289 |
141 | MP0005379_endocrine/exocrine_gland_phen | 0.71718469 |
142 | MP0001145_abnormal_male_reproductive | 0.71447960 |
143 | MP0004085_abnormal_heartbeat | 0.71379455 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Acute necrotizing encephalopathy (HP:0006965) | 5.50730602 |
2 | Abnormal mitochondria in muscle tissue (HP:0008316) | 5.09179426 |
3 | Progressive macrocephaly (HP:0004481) | 4.59372750 |
4 | Mitochondrial inheritance (HP:0001427) | 4.45439118 |
5 | Acute encephalopathy (HP:0006846) | 4.24208157 |
6 | Abnormal respiratory motile cilium physiology (HP:0012261) | 4.08351674 |
7 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 4.08340797 |
8 | Abnormal respiratory epithelium morphology (HP:0012253) | 3.88560756 |
9 | Abnormal respiratory motile cilium morphology (HP:0005938) | 3.88560756 |
10 | Myokymia (HP:0002411) | 3.85894439 |
11 | Abnormal ciliary motility (HP:0012262) | 3.84777016 |
12 | Increased CSF lactate (HP:0002490) | 3.80849044 |
13 | Hepatocellular necrosis (HP:0001404) | 3.60839216 |
14 | Gait imbalance (HP:0002141) | 3.50799078 |
15 | Medial flaring of the eyebrow (HP:0010747) | 3.43965465 |
16 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.36479890 |
17 | Absent/shortened dynein arms (HP:0200106) | 3.36479890 |
18 | Rhinitis (HP:0012384) | 3.31438431 |
19 | Congenital primary aphakia (HP:0007707) | 3.28391376 |
20 | Abnormality of glycolysis (HP:0004366) | 3.28179290 |
21 | Increased serum pyruvate (HP:0003542) | 3.28179290 |
22 | Occipital encephalocele (HP:0002085) | 3.26820619 |
23 | Nephrogenic diabetes insipidus (HP:0009806) | 3.11916894 |
24 | Increased hepatocellular lipid droplets (HP:0006565) | 3.08604642 |
25 | Atonic seizures (HP:0010819) | 3.03965094 |
26 | Optic disc pallor (HP:0000543) | 2.94945021 |
27 | Leukodystrophy (HP:0002415) | 2.87171137 |
28 | Focal motor seizures (HP:0011153) | 2.85537316 |
29 | Hypothermia (HP:0002045) | 2.84858364 |
30 | Exercise intolerance (HP:0003546) | 2.83301556 |
31 | Vaginal atresia (HP:0000148) | 2.70190097 |
32 | Hepatic necrosis (HP:0002605) | 2.68614057 |
33 | Genital tract atresia (HP:0001827) | 2.67785916 |
34 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.67694261 |
35 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.67694261 |
36 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.62317757 |
37 | Lipid accumulation in hepatocytes (HP:0006561) | 2.60913149 |
38 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.57770198 |
39 | Tubulointerstitial nephritis (HP:0001970) | 2.57020069 |
40 | Cystic liver disease (HP:0006706) | 2.56055424 |
41 | Bronchiectasis (HP:0002110) | 2.54101421 |
42 | Respiratory failure (HP:0002878) | 2.52893626 |
43 | Pancreatic fibrosis (HP:0100732) | 2.51743214 |
44 | Limb dystonia (HP:0002451) | 2.48739007 |
45 | Neuroendocrine neoplasm (HP:0100634) | 2.48660003 |
46 | Renal Fanconi syndrome (HP:0001994) | 2.48401592 |
47 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.45301319 |
48 | Postaxial foot polydactyly (HP:0001830) | 2.44118720 |
49 | Increased serum lactate (HP:0002151) | 2.41082831 |
50 | Pheochromocytoma (HP:0002666) | 2.41004249 |
51 | Abnormality of dentin (HP:0010299) | 2.40813100 |
52 | Increased intramyocellular lipid droplets (HP:0012240) | 2.40702024 |
53 | Nephronophthisis (HP:0000090) | 2.40238051 |
54 | Cerebral edema (HP:0002181) | 2.37230083 |
55 | Lactic acidosis (HP:0003128) | 2.32893357 |
56 | Poor coordination (HP:0002370) | 2.32050110 |
57 | Abnormality of the renal medulla (HP:0100957) | 2.31798928 |
58 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.29962257 |
59 | Bifid tongue (HP:0010297) | 2.29464722 |
60 | Abnormality of midbrain morphology (HP:0002418) | 2.28255946 |
61 | Molar tooth sign on MRI (HP:0002419) | 2.28255946 |
62 | Chronic bronchitis (HP:0004469) | 2.23909189 |
63 | Epileptic encephalopathy (HP:0200134) | 2.23847404 |
64 | True hermaphroditism (HP:0010459) | 2.22144854 |
65 | Male pseudohermaphroditism (HP:0000037) | 2.14054656 |
66 | Hyperglycinemia (HP:0002154) | 2.13790475 |
67 | Abnormal hair whorl (HP:0010721) | 2.10416091 |
68 | Abnormal number of erythroid precursors (HP:0012131) | 2.09055490 |
69 | Focal seizures (HP:0007359) | 2.05866222 |
70 | Cerebral hypomyelination (HP:0006808) | 2.02303229 |
71 | Emotional lability (HP:0000712) | 2.02084210 |
72 | Retinal dysplasia (HP:0007973) | 2.01011981 |
73 | Aplasia/Hypoplasia of the lens (HP:0008063) | 2.00044791 |
74 | Methylmalonic acidemia (HP:0002912) | 1.99931498 |
75 | Abnormality of the labia minora (HP:0012880) | 1.99270952 |
76 | Progressive cerebellar ataxia (HP:0002073) | 1.99152764 |
77 | Respiratory difficulties (HP:0002880) | 1.97897127 |
78 | Unsteady gait (HP:0002317) | 1.96993035 |
79 | Febrile seizures (HP:0002373) | 1.96314763 |
80 | Chronic hepatic failure (HP:0100626) | 1.93635450 |
81 | Delusions (HP:0000746) | 1.93374700 |
82 | Postaxial hand polydactyly (HP:0001162) | 1.93262676 |
83 | Absence seizures (HP:0002121) | 1.91803230 |
84 | Congenital hepatic fibrosis (HP:0002612) | 1.91011123 |
85 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 1.89505180 |
86 | Hypoplasia of the brainstem (HP:0002365) | 1.89505180 |
87 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.88872287 |
88 | Sclerocornea (HP:0000647) | 1.88214771 |
89 | Visual hallucinations (HP:0002367) | 1.87443519 |
90 | Pancreatic cysts (HP:0001737) | 1.86733807 |
91 | Infertility (HP:0000789) | 1.85084666 |
92 | Increased muscle lipid content (HP:0009058) | 1.83945118 |
93 | 3-Methylglutaconic aciduria (HP:0003535) | 1.83807109 |
94 | Specific learning disability (HP:0001328) | 1.82674137 |
95 | Anophthalmia (HP:0000528) | 1.82526279 |
96 | Septo-optic dysplasia (HP:0100842) | 1.82348681 |
97 | Amblyopia (HP:0000646) | 1.82051477 |
98 | Methylmalonic aciduria (HP:0012120) | 1.81210023 |
99 | X-linked dominant inheritance (HP:0001423) | 1.80575435 |
100 | Facial cleft (HP:0002006) | 1.77585873 |
101 | Broad foot (HP:0001769) | 1.77050205 |
102 | Exertional dyspnea (HP:0002875) | 1.76728909 |
103 | Polyphagia (HP:0002591) | 1.74351630 |
104 | Hyperventilation (HP:0002883) | 1.72303202 |
105 | Supernumerary spleens (HP:0009799) | 1.71507230 |
106 | Lissencephaly (HP:0001339) | 1.66707507 |
107 | Rimmed vacuoles (HP:0003805) | 1.66457369 |
108 | Hypoplastic left heart (HP:0004383) | 1.64417319 |
109 | Abnormality of renal resorption (HP:0011038) | 1.63997532 |
110 | Poor suck (HP:0002033) | 1.63747350 |
111 | Aganglionic megacolon (HP:0002251) | 1.63576309 |
112 | Delayed gross motor development (HP:0002194) | 1.63206545 |
113 | Anencephaly (HP:0002323) | 1.62529932 |
114 | Glycosuria (HP:0003076) | 1.61790987 |
115 | Abnormality of urine glucose concentration (HP:0011016) | 1.61790987 |
116 | Dialeptic seizures (HP:0011146) | 1.61402792 |
117 | Severe visual impairment (HP:0001141) | 1.61180788 |
118 | Renal dysplasia (HP:0000110) | 1.60304859 |
119 | Colon cancer (HP:0003003) | 1.59944985 |
120 | Hypoplastic pelvis (HP:0008839) | 1.59922409 |
121 | Oculomotor apraxia (HP:0000657) | 1.59328166 |
122 | Preaxial hand polydactyly (HP:0001177) | 1.59084271 |
123 | Renal hypoplasia (HP:0000089) | 1.58559256 |
124 | Median cleft lip (HP:0000161) | 1.58318715 |
125 | Decreased testicular size (HP:0008734) | 1.57765638 |
126 | Narrow forehead (HP:0000341) | 1.57448953 |
127 | Male infertility (HP:0003251) | 1.55900187 |
128 | Abnormal biliary tract physiology (HP:0012439) | 1.54811764 |
129 | Bile duct proliferation (HP:0001408) | 1.54811764 |
130 | Sensory axonal neuropathy (HP:0003390) | 1.54144786 |
131 | Furrowed tongue (HP:0000221) | 1.53895461 |
132 | Tubulointerstitial abnormality (HP:0001969) | 1.52750295 |
133 | Lethargy (HP:0001254) | 1.51700943 |
134 | Multicystic kidney dysplasia (HP:0000003) | 1.47252920 |
135 | Type I transferrin isoform profile (HP:0003642) | 1.46472871 |
136 | Chorioretinal coloboma (HP:0000567) | 1.46090409 |
137 | Short tibia (HP:0005736) | 1.45732891 |
138 | Optic nerve hypoplasia (HP:0000609) | 1.45453232 |
139 | Maternal diabetes (HP:0009800) | 1.44816395 |
140 | Congenital malformation of the right heart (HP:0011723) | 1.43996908 |
141 | Double outlet right ventricle (HP:0001719) | 1.43996908 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BUB1 | 3.84832673 |
2 | CASK | 3.31812639 |
3 | VRK2 | 3.13663566 |
4 | MAPK15 | 3.06904543 |
5 | STK16 | 2.95542340 |
6 | ARAF | 2.85756038 |
7 | MARK1 | 2.62096955 |
8 | MAP3K12 | 2.55548389 |
9 | EPHB2 | 2.51548419 |
10 | MAP2K7 | 2.17107352 |
11 | MAP3K4 | 2.09236869 |
12 | NTRK2 | 2.06801352 |
13 | MAPK13 | 2.02807194 |
14 | PDK3 | 1.96565563 |
15 | PDK4 | 1.96565563 |
16 | CCNB1 | 1.91228154 |
17 | BCKDK | 1.89526297 |
18 | BRAF | 1.86626298 |
19 | NME1 | 1.80228796 |
20 | DYRK2 | 1.75805106 |
21 | MINK1 | 1.73949127 |
22 | PBK | 1.73930435 |
23 | TESK1 | 1.67520584 |
24 | WEE1 | 1.65807905 |
25 | DAPK1 | 1.63833560 |
26 | PINK1 | 1.62127804 |
27 | ERBB3 | 1.59648962 |
28 | NUAK1 | 1.59107454 |
29 | LIMK1 | 1.58669136 |
30 | MST4 | 1.57087647 |
31 | CDK19 | 1.55277421 |
32 | PNCK | 1.52673425 |
33 | BCR | 1.49275929 |
34 | STK38L | 1.48684212 |
35 | TESK2 | 1.45429010 |
36 | EPHA4 | 1.44889898 |
37 | UHMK1 | 1.40547336 |
38 | PLK2 | 1.38683484 |
39 | CSNK1G1 | 1.35681542 |
40 | BMPR2 | 1.31777906 |
41 | TRIM28 | 1.30451023 |
42 | DAPK2 | 1.25530103 |
43 | MAP4K2 | 1.24442275 |
44 | DYRK3 | 1.22131047 |
45 | BRSK1 | 1.20229738 |
46 | FRK | 1.20216972 |
47 | TTK | 1.15051459 |
48 | SRPK1 | 1.13012349 |
49 | AURKA | 1.11941954 |
50 | TSSK6 | 1.10826373 |
51 | SIK3 | 1.09225130 |
52 | VRK1 | 1.08711040 |
53 | PHKG2 | 1.06290805 |
54 | PHKG1 | 1.06290805 |
55 | CDK18 | 1.05913421 |
56 | CDK14 | 1.05454795 |
57 | NTRK3 | 1.04206258 |
58 | MAP3K9 | 1.03405840 |
59 | PLK4 | 1.02894454 |
60 | PRKCG | 1.02217524 |
61 | GRK5 | 1.00961474 |
62 | CAMKK2 | 1.00606174 |
63 | TAF1 | 1.00290610 |
64 | MYLK | 0.99744870 |
65 | TNIK | 0.99085067 |
66 | CDK15 | 0.98719705 |
67 | CSNK1G3 | 0.98506955 |
68 | WNK3 | 0.97126413 |
69 | BRSK2 | 0.94295044 |
70 | PLK3 | 0.94264301 |
71 | INSRR | 0.93990391 |
72 | CDK11A | 0.92626146 |
73 | AKT3 | 0.92140171 |
74 | ZAK | 0.90258903 |
75 | PIM2 | 0.90218043 |
76 | ADRBK2 | 0.87500941 |
77 | PAK3 | 0.84107288 |
78 | TIE1 | 0.83997118 |
79 | PDK2 | 0.83094534 |
80 | DAPK3 | 0.82970381 |
81 | GRK1 | 0.82367513 |
82 | ILK | 0.80786288 |
83 | CAMK2B | 0.80719331 |
84 | PLK1 | 0.80184485 |
85 | KSR1 | 0.79821717 |
86 | EPHA2 | 0.79276742 |
87 | MAPKAPK5 | 0.79275221 |
88 | NTRK1 | 0.76759227 |
89 | NEK1 | 0.74911290 |
90 | ADRBK1 | 0.73787212 |
91 | CDK5 | 0.73510538 |
92 | CSNK1G2 | 0.72182827 |
93 | PRKCE | 0.71773692 |
94 | PTK2B | 0.69617760 |
95 | LATS1 | 0.69022509 |
96 | PRKCI | 0.67220169 |
97 | STK39 | 0.67191188 |
98 | ICK | 0.64990807 |
99 | TLK1 | 0.64835151 |
100 | NEK2 | 0.62695386 |
101 | MUSK | 0.61835064 |
102 | MAP2K4 | 0.60928735 |
103 | PRKD3 | 0.60852602 |
104 | ROCK2 | 0.59934548 |
105 | CAMK2A | 0.59856331 |
106 | LMTK2 | 0.59127963 |
107 | STK24 | 0.58791417 |
108 | PAK1 | 0.56529684 |
109 | PAK6 | 0.53426013 |
110 | CHEK2 | 0.52385934 |
111 | MKNK2 | 0.52316874 |
112 | NME2 | 0.51340954 |
113 | RPS6KA4 | 0.49488791 |
114 | RPS6KA2 | 0.47402737 |
115 | CDC7 | 0.46941747 |
116 | WNK4 | 0.46676692 |
117 | MET | 0.46524783 |
118 | OBSCN | 0.46346626 |
119 | OXSR1 | 0.46076915 |
120 | EIF2AK1 | 0.44157005 |
121 | DYRK1A | 0.44029521 |
122 | PASK | 0.43559811 |
123 | STK3 | 0.42859738 |
124 | ABL2 | 0.42808712 |
125 | AURKB | 0.42744186 |
126 | CDK3 | 0.42620800 |
127 | SGK223 | 0.41797871 |
128 | SGK494 | 0.41797871 |
129 | CSNK1A1 | 0.41750256 |
130 | LATS2 | 0.41311243 |
131 | MKNK1 | 0.40574310 |
132 | BMPR1B | 0.39947465 |
133 | MAPKAPK3 | 0.39315266 |
134 | GRK6 | 0.37629167 |
135 | CAMK2D | 0.36157917 |
136 | CSNK1A1L | 0.36018664 |
137 | YES1 | 0.35276233 |
138 | ACVR1B | 0.34721511 |
139 | GRK7 | 0.34498346 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.45193269 |
2 | Parkinsons disease_Homo sapiens_hsa05012 | 4.02220800 |
3 | Proteasome_Homo sapiens_hsa03050 | 3.70537230 |
4 | Huntingtons disease_Homo sapiens_hsa05016 | 3.25489070 |
5 | Alzheimers disease_Homo sapiens_hsa05010 | 2.99266006 |
6 | Ribosome_Homo sapiens_hsa03010 | 2.87863520 |
7 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.45172083 |
8 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.36169057 |
9 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.35629970 |
10 | RNA polymerase_Homo sapiens_hsa03020 | 2.35038198 |
11 | Olfactory transduction_Homo sapiens_hsa04740 | 2.28691085 |
12 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.10425339 |
13 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.03511992 |
14 | Nicotine addiction_Homo sapiens_hsa05033 | 2.00846320 |
15 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.95304728 |
16 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.86850093 |
17 | Spliceosome_Homo sapiens_hsa03040 | 1.84930659 |
18 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.77357168 |
19 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.76566344 |
20 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.74942402 |
21 | Phototransduction_Homo sapiens_hsa04744 | 1.70959660 |
22 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.59504308 |
23 | Mismatch repair_Homo sapiens_hsa03430 | 1.53023392 |
24 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.50005260 |
25 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.49125010 |
26 | Peroxisome_Homo sapiens_hsa04146 | 1.47657071 |
27 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.47526721 |
28 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.45957510 |
29 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.44836392 |
30 | DNA replication_Homo sapiens_hsa03030 | 1.44835662 |
31 | Protein export_Homo sapiens_hsa03060 | 1.44828411 |
32 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.37921975 |
33 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.37915945 |
34 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.37888129 |
35 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.34930994 |
36 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.31516962 |
37 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.29643641 |
38 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.29500524 |
39 | Sulfur relay system_Homo sapiens_hsa04122 | 1.28549247 |
40 | Circadian entrainment_Homo sapiens_hsa04713 | 1.26189807 |
41 | Basal transcription factors_Homo sapiens_hsa03022 | 1.24926237 |
42 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.24634612 |
43 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.24604615 |
44 | GABAergic synapse_Homo sapiens_hsa04727 | 1.23558882 |
45 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.23414124 |
46 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.22194541 |
47 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.21292117 |
48 | Long-term potentiation_Homo sapiens_hsa04720 | 1.19610794 |
49 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.18891164 |
50 | RNA transport_Homo sapiens_hsa03013 | 1.17539565 |
51 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.16366095 |
52 | Purine metabolism_Homo sapiens_hsa00230 | 1.14794643 |
53 | Taste transduction_Homo sapiens_hsa04742 | 1.14316790 |
54 | Morphine addiction_Homo sapiens_hsa05032 | 1.13939164 |
55 | Base excision repair_Homo sapiens_hsa03410 | 1.13771101 |
56 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.13713958 |
57 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.11106396 |
58 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.07782346 |
59 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.06478572 |
60 | Homologous recombination_Homo sapiens_hsa03440 | 1.03599215 |
61 | Alcoholism_Homo sapiens_hsa05034 | 0.99476276 |
62 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.97454082 |
63 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.96698203 |
64 | Cell cycle_Homo sapiens_hsa04110 | 0.95940459 |
65 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.95799153 |
66 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.93256621 |
67 | Retinol metabolism_Homo sapiens_hsa00830 | 0.92773212 |
68 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.90521191 |
69 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.88701344 |
70 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.87315772 |
71 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.85571870 |
72 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.84274830 |
73 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.82217453 |
74 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.79286981 |
75 | Gap junction_Homo sapiens_hsa04540 | 0.78906748 |
76 | RNA degradation_Homo sapiens_hsa03018 | 0.77877389 |
77 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.76827103 |
78 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.76253812 |
79 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.76218103 |
80 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.75828352 |
81 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.75036351 |
82 | Axon guidance_Homo sapiens_hsa04360 | 0.73245495 |
83 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.71040383 |
84 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.69335114 |
85 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.68874296 |
86 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.68373937 |
87 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.68077404 |
88 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.66977689 |
89 | Insulin secretion_Homo sapiens_hsa04911 | 0.66269067 |
90 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.65772533 |
91 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.65149053 |
92 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.61098063 |
93 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.59632311 |
94 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.58987490 |
95 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.58769705 |
96 | Melanogenesis_Homo sapiens_hsa04916 | 0.58682665 |
97 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.58344929 |
98 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.58224518 |
99 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.57878241 |
100 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.56731668 |
101 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.56588167 |
102 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.56257789 |
103 | Cocaine addiction_Homo sapiens_hsa05030 | 0.56153755 |
104 | Long-term depression_Homo sapiens_hsa04730 | 0.55625495 |
105 | Histidine metabolism_Homo sapiens_hsa00340 | 0.55059494 |
106 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.55016735 |
107 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.54424982 |
108 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.54397094 |
109 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.53456027 |
110 | Salivary secretion_Homo sapiens_hsa04970 | 0.52486562 |
111 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.52211364 |
112 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.50545398 |
113 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.50396216 |
114 | Tight junction_Homo sapiens_hsa04530 | 0.49980926 |
115 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.48694328 |
116 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.47610381 |
117 | Renin secretion_Homo sapiens_hsa04924 | 0.46106690 |
118 | Carbon metabolism_Homo sapiens_hsa01200 | 0.44661785 |
119 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.44413599 |
120 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.44304905 |
121 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.42334600 |
122 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.42142024 |
123 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.41699342 |
124 | Metabolic pathways_Homo sapiens_hsa01100 | 0.41430268 |
125 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.40290095 |
126 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.38532711 |
127 | Colorectal cancer_Homo sapiens_hsa05210 | 0.37107566 |
128 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.36903331 |
129 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.34954372 |
130 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.34831196 |
131 | Phagosome_Homo sapiens_hsa04145 | 0.32506763 |
132 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.31478191 |
133 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.30781785 |
134 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.28634513 |
135 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.28509108 |
136 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.28245954 |
137 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.24589801 |
138 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.24472581 |
139 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.23420603 |
140 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.23379357 |
141 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.22936844 |
142 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.20646016 |
143 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.18766042 |
144 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.18111916 |
145 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.17803513 |
146 | Glioma_Homo sapiens_hsa05214 | 0.17703414 |