CC2D1B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.24024156
2antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.24024156
3positive regulation of gamma-delta T cell activation (GO:0046645)4.14226956
4protein localization to endosome (GO:0036010)3.90796785
5germinal center formation (GO:0002467)3.82688357
6antigen processing and presentation of endogenous antigen (GO:0019883)3.81566107
7regulation of gamma-delta T cell differentiation (GO:0045586)3.77597078
8response to peptidoglycan (GO:0032494)3.71847097
9negative regulation of interleukin-12 production (GO:0032695)3.65939477
10nuclear pore complex assembly (GO:0051292)3.56808969
11positive regulation of histone deacetylation (GO:0031065)3.54364568
12DNA unwinding involved in DNA replication (GO:0006268)3.53753682
13regulation of translational fidelity (GO:0006450)3.51940213
14macrophage activation involved in immune response (GO:0002281)3.49455576
15mannose metabolic process (GO:0006013)3.44594609
16modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.44088015
17positive regulation by organism of defense response of other organism involved in symbiotic interact3.44088015
18modulation by symbiont of host immune response (GO:0052553)3.44088015
19positive regulation by symbiont of host defense response (GO:0052509)3.44088015
20modulation by symbiont of host defense response (GO:0052031)3.44088015
21modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.44088015
22heterochromatin organization (GO:0070828)3.42676794
23regulation of gamma-delta T cell activation (GO:0046643)3.41660203
24folic acid-containing compound biosynthetic process (GO:0009396)3.37560542
25response to muramyl dipeptide (GO:0032495)3.36322593
26positive thymic T cell selection (GO:0045059)3.34831507
27nuclear pore organization (GO:0006999)3.34175756
28NIK/NF-kappaB signaling (GO:0038061)3.31415548
29negative regulation of histone methylation (GO:0031061)3.29305352
30regulation of posttranscriptional gene silencing (GO:0060147)3.27608449
31regulation of gene silencing by miRNA (GO:0060964)3.27608449
32regulation of gene silencing by RNA (GO:0060966)3.27608449
33protein localization to kinetochore (GO:0034501)3.27185263
34pre-miRNA processing (GO:0031054)3.25929696
35COPI coating of Golgi vesicle (GO:0048205)3.24534793
36Golgi transport vesicle coating (GO:0048200)3.24534793
37lipopolysaccharide-mediated signaling pathway (GO:0031663)3.24428837
38response to type I interferon (GO:0034340)3.17402314
39antigen processing and presentation via MHC class Ib (GO:0002475)3.16198597
40tolerance induction (GO:0002507)3.15244757
41negative regulation of erythrocyte differentiation (GO:0045647)3.15091007
42cellular response to type I interferon (GO:0071357)3.14588377
43type I interferon signaling pathway (GO:0060337)3.14588377
44chromatin assembly (GO:0031497)3.13810797
45antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.12944867
46positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.12424747
47DNA duplex unwinding (GO:0032508)3.11489432
48DNA geometric change (GO:0032392)3.08135132
49IMP biosynthetic process (GO:0006188)3.03790250
50maternal placenta development (GO:0001893)3.03315846
51somatic diversification of immune receptors via somatic mutation (GO:0002566)3.02769724
52somatic hypermutation of immunoglobulin genes (GO:0016446)3.02769724
53regulation of type I interferon-mediated signaling pathway (GO:0060338)3.02172512
54regulation of vitamin D biosynthetic process (GO:0060556)3.01333137
55determination of adult lifespan (GO:0008340)2.97367218
56regulation of histone H3-K9 methylation (GO:0051570)2.97278884
57cellular extravasation (GO:0045123)2.96878091
58regulation of interleukin-12 biosynthetic process (GO:0045075)2.95915928
59regulation of T-helper 2 cell differentiation (GO:0045628)2.95742610
60dosage compensation (GO:0007549)2.95529016
61regulation of interferon-beta biosynthetic process (GO:0045357)2.94205178
62positive regulation of protein deacetylation (GO:0090312)2.90524929
63detection of other organism (GO:0098543)2.88843657
64regulation of dendritic cell antigen processing and presentation (GO:0002604)2.85049976
65pore complex assembly (GO:0046931)2.84257681
66histone H4-K12 acetylation (GO:0043983)2.84090613
67detection of molecule of bacterial origin (GO:0032490)2.83772319
68positive regulation of SMAD protein import into nucleus (GO:0060391)2.82970604
69positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.82388675
70mitotic nuclear envelope disassembly (GO:0007077)2.82263425
71regulation of translational termination (GO:0006449)2.82074113
72RNA stabilization (GO:0043489)2.81967170
73mRNA stabilization (GO:0048255)2.81967170
74leukocyte aggregation (GO:0070486)2.80990988
75positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.80391218
76positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.80319876
77negative regulation of T cell mediated immunity (GO:0002710)2.79249028
78mitotic chromosome condensation (GO:0007076)2.75549205
79T cell migration (GO:0072678)2.74316717
80detection of bacterium (GO:0016045)2.74305775
81neutrophil activation involved in immune response (GO:0002283)2.73907992
82cytoplasmic mRNA processing body assembly (GO:0033962)2.70820441
83peptidyl-lysine dimethylation (GO:0018027)2.70612772
84membrane disassembly (GO:0030397)2.69015010
85nuclear envelope disassembly (GO:0051081)2.69015010
86regulation of T-helper 1 cell differentiation (GO:0045625)2.67015964
87detection of external biotic stimulus (GO:0098581)2.66658240
88thymic T cell selection (GO:0045061)2.65489943
89activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.65308948
90immunoglobulin mediated immune response (GO:0016064)2.65118879
91regulation of interleukin-2 biosynthetic process (GO:0045076)2.64398157
92positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.64230194
93regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.64144723
94positive regulation of nuclease activity (GO:0032075)2.64079899
95myeloid dendritic cell differentiation (GO:0043011)2.63788040
96trophectodermal cell differentiation (GO:0001829)2.63409816
97response to protozoan (GO:0001562)2.62308843
98protein localization to chromosome, centromeric region (GO:0071459)2.61779194
99interferon-gamma-mediated signaling pathway (GO:0060333)2.60618304
100defense response to protozoan (GO:0042832)2.60571136
101regulation of mast cell degranulation (GO:0043304)2.59615990
102CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.58512504
103NLS-bearing protein import into nucleus (GO:0006607)2.58224324
104positive regulation of type 2 immune response (GO:0002830)2.57517222
105negative regulation of innate immune response (GO:0045824)2.57318097
106regulation of necroptotic process (GO:0060544)2.55603605
107IMP metabolic process (GO:0046040)2.55146306
108snRNA metabolic process (GO:0016073)2.54932639
109negative regulation of cytokine production involved in immune response (GO:0002719)2.54719361
110formation of translation preinitiation complex (GO:0001731)2.54295710
111intracellular estrogen receptor signaling pathway (GO:0030520)2.53929728
112regulation of T cell tolerance induction (GO:0002664)2.53857825
113negative regulation of gene silencing (GO:0060969)2.53344078
114regulation of leukocyte degranulation (GO:0043300)2.52761504
115DNA replication-dependent nucleosome organization (GO:0034723)2.52138981
116DNA replication-dependent nucleosome assembly (GO:0006335)2.52138981
117regulation of nuclease activity (GO:0032069)2.51163694
118regulation of RNA export from nucleus (GO:0046831)2.50905790
119regulation of NFAT protein import into nucleus (GO:0051532)2.50625817
120histone mRNA catabolic process (GO:0071044)2.50193763
121JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.49146234
122positive regulation of gene expression, epigenetic (GO:0045815)2.49070260
123positive regulation of B cell differentiation (GO:0045579)2.47310041
124barbed-end actin filament capping (GO:0051016)2.47157002
125glycosphingolipid catabolic process (GO:0046479)2.45185893
126modulation by symbiont of host cellular process (GO:0044068)2.43260920
127regulation of antigen processing and presentation (GO:0002577)2.43018356
128regulation of type 2 immune response (GO:0002828)2.42879163
129apoptotic process involved in morphogenesis (GO:0060561)2.42118099
130amino sugar catabolic process (GO:0046348)2.41929140
131chromatin silencing (GO:0006342)2.41915517
132negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.41743224
133regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.41713497
134snRNA processing (GO:0016180)2.41527201
135natural killer cell differentiation (GO:0001779)2.40841125
136nuclear envelope organization (GO:0006998)2.40227317
137B cell receptor signaling pathway (GO:0050853)2.40139709
138negative regulation of lymphocyte mediated immunity (GO:0002707)2.40119973
139regulation of B cell receptor signaling pathway (GO:0050855)2.39908871
140regulation of gene silencing (GO:0060968)2.39401772
141sister chromatid segregation (GO:0000819)2.39231085
142regulation of interferon-alpha production (GO:0032647)2.38912091
143regulation of SMAD protein import into nucleus (GO:0060390)2.37909593
144response to laminar fluid shear stress (GO:0034616)2.37848127
145cellular response to thyroid hormone stimulus (GO:0097067)2.37037655
146positive T cell selection (GO:0043368)2.36911634
147positive regulation of cellular amide metabolic process (GO:0034250)2.36800866
148response to UV-C (GO:0010225)2.36258517
149histone H4-K5 acetylation (GO:0043981)2.36217772
150histone H4-K8 acetylation (GO:0043982)2.36217772
151negative regulation of leukocyte mediated immunity (GO:0002704)2.36091080
152myeloid cell activation involved in immune response (GO:0002275)2.35935639
153histone H4-K16 acetylation (GO:0043984)2.35414281
154granulocyte activation (GO:0036230)2.35291887
155interferon-gamma secretion (GO:0072643)2.35200867
156cellular hyperosmotic response (GO:0071474)2.34765712
157regulation of myeloid leukocyte mediated immunity (GO:0002886)2.34396716
158positive regulation of Rap GTPase activity (GO:0032854)2.33397539
159positive regulation of natural killer cell differentiation (GO:0032825)2.33281593
160regulation of vitamin metabolic process (GO:0030656)2.33172889
161T-helper 1 type immune response (GO:0042088)2.33172296
162positive regulation of interferon-alpha production (GO:0032727)2.33042647
163regulation of hippo signaling (GO:0035330)2.32722425
164positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.32023368
165negative regulation of gene expression, epigenetic (GO:0045814)2.31468593
166negative regulation of interleukin-6 production (GO:0032715)2.31430529
167cellular response to ethanol (GO:0071361)2.31179556
168positive regulation of antigen processing and presentation (GO:0002579)2.30910357
169DNA conformation change (GO:0071103)2.30080075
170negative regulation of cell killing (GO:0031342)2.30036724
171negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.30036724
172negative thymic T cell selection (GO:0045060)2.28990584
173gene silencing (GO:0016458)2.28535094
174mitotic sister chromatid segregation (GO:0000070)2.27613647
175negative T cell selection (GO:0043383)2.25965537
176mitotic G1 DNA damage checkpoint (GO:0031571)2.25837070
177endoplasmic reticulum unfolded protein response (GO:0030968)2.25836812
178histone H2A monoubiquitination (GO:0035518)2.25763930
179spliceosomal tri-snRNP complex assembly (GO:0000244)2.23715091
180mRNA cleavage (GO:0006379)2.22706227
181L-alpha-amino acid transmembrane transport (GO:1902475)2.22486736
182T cell selection (GO:0045058)2.22286192
183negative regulation of bone resorption (GO:0045779)2.20331600

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.14121097
2MYC_22102868_ChIP-Seq_BL_Human3.70340875
3EGR1_19374776_ChIP-ChIP_THP-1_Human3.49269882
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.11613931
5VDR_21846776_ChIP-Seq_THP-1_Human2.67391988
6NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.63089885
7IRF8_21731497_ChIP-ChIP_J774_Mouse2.51796004
8EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.29558216
9IRF8_27001747_Chip-Seq_BMDM_Mouse2.19445163
10RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.18321421
11TCF7_22412390_ChIP-Seq_EML_Mouse1.98690909
12BP1_19119308_ChIP-ChIP_Hs578T_Human1.97563089
13THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.93426760
14RARG_19884340_ChIP-ChIP_MEFs_Mouse1.90553560
15MYC_18555785_ChIP-Seq_MESCs_Mouse1.86125786
16VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.85417061
17MAF_26560356_Chip-Seq_TH1_Human1.84586855
18IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.78380970
19KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.76229520
20E2F4_17652178_ChIP-ChIP_JURKAT_Human1.75943658
21* KDM2B_26808549_Chip-Seq_DND41_Human1.73978055
22TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.73445249
23UTX_26944678_Chip-Seq_JUKART_Human1.72469020
24STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.72208347
25* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.71791990
26TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.71632886
27IRF8_22096565_ChIP-ChIP_GC-B_Human1.71526970
28FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.70246734
29ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.69353852
30MYC_19079543_ChIP-ChIP_MESCs_Mouse1.68061403
31* ELK3_25401928_ChIP-Seq_HUVEC_Human1.63249447
32CIITA_25753668_ChIP-Seq_RAJI_Human1.58237542
33* MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.55073459
34MYB_26560356_Chip-Seq_TH1_Human1.53668872
35STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.53315662
36E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.52131828
37MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.51101718
38Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.49179988
39SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.48492526
40SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.48394183
41MYB_26560356_Chip-Seq_TH2_Human1.47932293
42KDM2B_26808549_Chip-Seq_SUP-B15_Human1.46733625
43* KDM2B_26808549_Chip-Seq_K562_Human1.46313451
44ESR2_21235772_ChIP-Seq_MCF-7_Human1.45976984
45VDR_24763502_ChIP-Seq_THP-1_Human1.45941439
46RUNX_20019798_ChIP-Seq_JUKART_Human1.44332646
47E2F1_21310950_ChIP-Seq_MCF-7_Human1.43628186
48BRD4_27068464_Chip-Seq_AML-cells_Mouse1.43484496
49CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.43404399
50TP63_17297297_ChIP-ChIP_HaCaT_Human1.42678640
51SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.41739441
52TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.41539748
53* CTCF_27219007_Chip-Seq_ERYTHROID_Human1.40452171
54* TFEB_21752829_ChIP-Seq_HELA_Human1.40224545
55PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.39770936
56TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.38612022
57SCL_19346495_ChIP-Seq_HPC-7_Human1.38528193
58GATA1_19941827_ChIP-Seq_MEL_Mouse1.38199641
59* RUNX1_22412390_ChIP-Seq_EML_Mouse1.37885996
60FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.33809640
61* CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.32589461
62* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.31874765
63NCOR1_26117541_ChIP-Seq_K562_Human1.31139528
64DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.30072349
65MYB_21317192_ChIP-Seq_ERMYB_Mouse1.28647458
66KDM5A_27292631_Chip-Seq_BREAST_Human1.27980990
67STAT3_1855785_ChIP-Seq_MESCs_Mouse1.27080574
68GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.26807954
69STAT6_21828071_ChIP-Seq_BEAS2B_Human1.25128712
70KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.24822403
71KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.24822403
72KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.24822403
73* MAF_26560356_Chip-Seq_TH2_Human1.24647779
74XRN2_22483619_ChIP-Seq_HELA_Human1.24285625
75* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.24207551
76* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.24032444
77* LXR_22292898_ChIP-Seq_THP-1_Human1.23934022
78NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.23120208
79* SPI1_23547873_ChIP-Seq_NB4_Human1.21953364
80CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.21665478
81* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.21568728
82EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.21034556
83SMAD_19615063_ChIP-ChIP_OVARY_Human1.20572223
84* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.20385783
85GATA1_19941826_ChIP-Seq_K562_Human1.20113845
86SA1_27219007_Chip-Seq_ERYTHROID_Human1.18095210
87NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.17112358
88VDR_24787735_ChIP-Seq_THP-1_Human1.15558026
89ZNF263_19887448_ChIP-Seq_K562_Human1.15473013
90* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.14222640
91IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.13421357
92BCOR_27268052_Chip-Seq_Bcells_Human1.13353813
93* KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.13099641
94* RACK7_27058665_Chip-Seq_MCF-7_Human1.12902014
95SPI1_23127762_ChIP-Seq_K562_Human1.12736862
96GATA2_21666600_ChIP-Seq_HMVEC_Human1.12398558
97ATF3_27146783_Chip-Seq_COLON_Human1.12390478
98* PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.12371010
99* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.11829970
100KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.11504807
101TP53_22127205_ChIP-Seq_IMR90_Human1.11429940
102GATA2_22383799_ChIP-Seq_G1ME_Mouse1.11081398
103* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.10868091
104POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.10605759
105SMC4_20622854_ChIP-Seq_HELA_Human1.10381320
106CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.10067205
107PU_27001747_Chip-Seq_BMDM_Mouse1.09321080
108TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.08753644
109RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.08523491
110* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.07851095
111CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.07310716
112NELFA_20434984_ChIP-Seq_ESCs_Mouse1.07268399
113NANOG_18555785_ChIP-Seq_MESCs_Mouse1.07117974
114PU.1_20513432_ChIP-Seq_Bcells_Mouse1.06827092
115HIF1A_21447827_ChIP-Seq_MCF-7_Human1.05138448
116AR_21909140_ChIP-Seq_LNCAP_Human1.04516335
117UBF1/2_26484160_Chip-Seq_HMECs_Human1.04341505
118P300_27058665_Chip-Seq_ZR-75-30cells_Human1.04107198
119NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.03866233
120ELF1_20517297_ChIP-Seq_JURKAT_Human1.03510068
121RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.02955192
122LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.02657001
123BCL6_27268052_Chip-Seq_Bcells_Human1.02156374
124CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.02146033
125SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.01994907
126PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.01943515
127SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.01938908
128P68_20966046_ChIP-Seq_HELA_Human1.01747400
129STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.00981375
130GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.00945268
131SRY_22984422_ChIP-ChIP_TESTIS_Rat1.00443549
132TP63_19390658_ChIP-ChIP_HaCaT_Human0.99409387
133CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.99340002
134* SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.98458365
135* KDM2B_26808549_Chip-Seq_JURKAT_Human0.97982112
136GATA1_22383799_ChIP-Seq_G1ME_Mouse0.97891982
137MYCN_18555785_ChIP-Seq_MESCs_Mouse0.97713186
138TET1_21451524_ChIP-Seq_MESCs_Mouse0.97312996
139FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.96401885
140ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.95710928
141* ZFX_18555785_ChIP-Seq_MESCs_Mouse0.95607808
142ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.95582687
143ZFP281_27345836_Chip-Seq_ESCs_Mouse0.95435780
144POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.95334820
145STAT4_19710469_ChIP-ChIP_TH1__Mouse0.94804644
146TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.94787198
147MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.94424179

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003705_abnormal_hypodermis_morpholog2.99910375
2MP0010352_gastrointestinal_tract_polyps2.96370695
3MP0009840_abnormal_foam_cell2.94686167
4MP0005451_abnormal_body_composition2.88212272
5MP0003724_increased_susceptibility_to2.64248547
6MP0002419_abnormal_innate_immunity2.32996799
7MP0004510_myositis2.30223482
8MP0003300_gastrointestinal_ulcer2.30081898
9MP0010307_abnormal_tumor_latency2.23735575
10MP0002148_abnormal_hypersensitivity_rea2.23521368
11MP0002396_abnormal_hematopoietic_system2.21596816
12MP0003763_abnormal_thymus_physiology2.20225165
13MP0003693_abnormal_embryo_hatching2.19455946
14MP0009785_altered_susceptibility_to2.16129537
15MP0005076_abnormal_cell_differentiation2.12332920
16MP0009278_abnormal_bone_marrow2.11838383
17MP0003566_abnormal_cell_adhesion2.07388536
18MP0003111_abnormal_nucleus_morphology2.06918902
19MP0000685_abnormal_immune_system1.98940203
20MP0004957_abnormal_blastocyst_morpholog1.98850841
21MP0003191_abnormal_cellular_cholesterol1.98058213
22MP0002877_abnormal_melanocyte_morpholog1.97690970
23MP0008057_abnormal_DNA_replication1.95193100
24MP0010094_abnormal_chromosome_stability1.92615700
25MP0001533_abnormal_skeleton_physiology1.86124293
26MP0003077_abnormal_cell_cycle1.85289260
27MP0003172_abnormal_lysosome_physiology1.84513330
28MP0004808_abnormal_hematopoietic_stem1.82054960
29MP0002998_abnormal_bone_remodeling1.76335391
30MP0001849_ear_inflammation1.74766781
31MP0001730_embryonic_growth_arrest1.72540506
32MP0002398_abnormal_bone_marrow1.64403142
33MP0001790_abnormal_immune_system1.61658987
34MP0005387_immune_system_phenotype1.61658987
35MP0004947_skin_inflammation1.59343271
36MP0001800_abnormal_humoral_immune1.59163216
37MP0000350_abnormal_cell_proliferation1.57919014
38MP0000703_abnormal_thymus_morphology1.56841755
39MP0005058_abnormal_lysosome_morphology1.54792232
40MP0004264_abnormal_extraembryonic_tissu1.51820535
41MP0003279_aneurysm1.50287445
42MP0000537_abnormal_urethra_morphology1.47851128
43MP0000490_abnormal_crypts_of1.47589521
44MP0000604_amyloidosis1.40769141
45MP0005023_abnormal_wound_healing1.39490023
46MP0000569_abnormal_digit_pigmentation1.39198671
47MP0002405_respiratory_system_inflammati1.39030908
48MP0002722_abnormal_immune_system1.38257947
49MP0003828_pulmonary_edema1.37848244
50MP0003303_peritoneal_inflammation1.37562946
51MP0008260_abnormal_autophagy1.37121642
52MP0002452_abnormal_antigen_presenting1.35002118
53MP0001835_abnormal_antigen_presentation1.34801152
54MP0000689_abnormal_spleen_morphology1.34713480
55MP0004197_abnormal_fetal_growth/weight/1.33949118
56MP0002420_abnormal_adaptive_immunity1.33661925
57MP0009333_abnormal_splenocyte_physiolog1.33525847
58MP0002166_altered_tumor_susceptibility1.32923785
59MP0000343_altered_response_to1.31146625
60MP0008961_abnormal_basal_metabolism1.30887078
61MP0001819_abnormal_immune_cell1.30842263
62MP0004185_abnormal_adipocyte_glucose1.29480400
63MP0010234_abnormal_vibrissa_follicle1.29280344
64MP0000716_abnormal_immune_system1.28532578
65MP0005310_abnormal_salivary_gland1.27712180
66MP0008469_abnormal_protein_level1.26199582
67MP0001672_abnormal_embryogenesis/_devel1.23199841
68MP0005380_embryogenesis_phenotype1.23199841
69MP0009764_decreased_sensitivity_to1.23126082
70MP0002086_abnormal_extraembryonic_tissu1.23099770
71MP0000733_abnormal_muscle_development1.23013397
72MP0008007_abnormal_cellular_replicative1.21454896
73MP0003984_embryonic_growth_retardation1.21219352
74MP0002088_abnormal_embryonic_growth/wei1.20649609
75MP0002723_abnormal_immune_serum1.20563341
76MP0002429_abnormal_blood_cell1.19929361
77MP0002019_abnormal_tumor_incidence1.19613891
78MP0001545_abnormal_hematopoietic_system1.18913954
79MP0005397_hematopoietic_system_phenotyp1.18913954
80MP0000465_gastrointestinal_hemorrhage1.18390336
81MP0003436_decreased_susceptibility_to1.17351856
82MP0010155_abnormal_intestine_physiology1.16724883
83MP0003283_abnormal_digestive_organ1.16651810
84MP0005000_abnormal_immune_tolerance1.15595963
85MP0000015_abnormal_ear_pigmentation1.14723749
86MP0001853_heart_inflammation1.14187123
87MP0002084_abnormal_developmental_patter1.12306282
88MP0002080_prenatal_lethality1.11261015
89MP0008058_abnormal_DNA_repair1.11059689
90MP0001958_emphysema1.10258774
91MP0001697_abnormal_embryo_size1.09806410
92MP0003075_altered_response_to1.09438351
93MP0004381_abnormal_hair_follicle1.09069113
94MP0000313_abnormal_cell_death1.08750479
95MP0000858_altered_metastatic_potential1.08160750
96MP0001873_stomach_inflammation1.06824287
97MP0002085_abnormal_embryonic_tissue1.06036238
98MP0001851_eye_inflammation1.04121008
99MP0006082_CNS_inflammation1.03488215
100MP0004233_abnormal_muscle_weight1.02986059
101MP0003091_abnormal_cell_migration1.02575181
102MP0002332_abnormal_exercise_endurance1.00754348
103MP0008004_abnormal_stomach_pH0.96680421
104MP0005671_abnormal_response_to0.96458697
105MP0009672_abnormal_birth_weight0.95808810
106MP0000371_diluted_coat_color0.94756188
107MP0000767_abnormal_smooth_muscle0.94492854
108MP0003866_abnormal_defecation0.94412794
109MP0004130_abnormal_muscle_cell0.94038503
110MP0000003_abnormal_adipose_tissue0.93730324
111MP0005164_abnormal_response_to0.93296333
112MP0003448_altered_tumor_morphology0.92838009
113MP0005464_abnormal_platelet_physiology0.92702117
114MP0002933_joint_inflammation0.90924268
115MP0003453_abnormal_keratinocyte_physiol0.90413073
116MP0006054_spinal_hemorrhage0.90156843
117MP0005621_abnormal_cell_physiology0.89928462
118MP0000428_abnormal_craniofacial_morphol0.89387961
119MP0000477_abnormal_intestine_morphology0.87492157
120MP0005390_skeleton_phenotype0.86288006
121MP0003329_amyloid_beta_deposits0.84727441
122MP0004858_abnormal_nervous_system0.84470194
123MP0003795_abnormal_bone_structure0.83521221
124MP0008438_abnormal_cutaneous_collagen0.82537315
125MP0009703_decreased_birth_body0.82249012
126MP0005025_abnormal_response_to0.81781872
127MP0001348_abnormal_lacrimal_gland0.81500370
128MP0003045_fibrosis0.80525565
129MP0002006_tumorigenesis0.80259411
130MP0003656_abnormal_erythrocyte_physiolo0.79766467
131MP0002925_abnormal_cardiovascular_devel0.78252293
132MP0001845_abnormal_inflammatory_respons0.77293996
133MP0008770_decreased_survivor_rate0.76402612
134MP0001915_intracranial_hemorrhage0.75922227
135MP0001663_abnormal_digestive_system0.75584898
136MP0005166_decreased_susceptibility_to0.75302517
137MP0001216_abnormal_epidermal_layer0.75221410
138MP0000249_abnormal_blood_vessel0.75008825
139MP0002139_abnormal_hepatobiliary_system0.73919755
140MP0003690_abnormal_glial_cell0.73626783
141MP0005257_abnormal_intraocular_pressure0.73365480
142MP0003890_abnormal_embryonic-extraembry0.72556927
143MP0005384_cellular_phenotype0.72534693
144MP0004883_abnormal_blood_vessel0.71966884
145MP0003183_abnormal_peptide_metabolism0.69186841
146MP0005409_darkened_coat_color0.66870641

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of glycolipid metabolism (HP:0010969)4.75227243
2Abnormality of liposaccharide metabolism (HP:0010968)4.75227243
3Abnormality of glycosphingolipid metabolism (HP:0004343)4.75227243
4Abnormality of macrophages (HP:0004311)3.67409946
5Recurrent abscess formation (HP:0002722)3.56458368
6Increased cerebral lipofuscin (HP:0011813)3.49485198
7Recurrent bacterial skin infections (HP:0005406)3.43960824
8Loss of speech (HP:0002371)3.42604279
9Ependymoma (HP:0002888)3.41263624
10Myositis (HP:0100614)3.13717365
11Cerebral aneurysm (HP:0004944)3.11740860
12Abnormality of the fingertips (HP:0001211)3.05132900
13Orchitis (HP:0100796)3.04715798
14Increased neuronal autofluorescent lipopigment (HP:0002074)2.96395066
15Ulnar bowing (HP:0003031)2.91468391
16Nasal polyposis (HP:0100582)2.76870315
17Mediastinal lymphadenopathy (HP:0100721)2.76294568
18T lymphocytopenia (HP:0005403)2.73341235
19Systemic lupus erythematosus (HP:0002725)2.72331047
20Retrobulbar optic neuritis (HP:0100654)2.72189371
21Optic neuritis (HP:0100653)2.72189371
22Hand muscle atrophy (HP:0009130)2.60723138
23Basal cell carcinoma (HP:0002671)2.58849573
24Recurrent bronchitis (HP:0002837)2.56969639
25Vacuolated lymphocytes (HP:0001922)2.51053082
26Distal upper limb amyotrophy (HP:0007149)2.48305812
27Upper limb amyotrophy (HP:0009129)2.48305812
28Recurrent viral infections (HP:0004429)2.45102826
29Hyperacusis (HP:0010780)2.43922729
30Abnormality of T cell number (HP:0011839)2.43411905
31Vertebral compression fractures (HP:0002953)2.42815568
32Stomatitis (HP:0010280)2.42434303
33Selective tooth agenesis (HP:0001592)2.41452494
34Nuclear cataract (HP:0100018)2.37916933
35Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.37782393
36Heterotopia (HP:0002282)2.36326308
37Gastrointestinal stroma tumor (HP:0100723)2.36064682
38Spontaneous hematomas (HP:0007420)2.35295307
39Pustule (HP:0200039)2.34853383
40Recurrent skin infections (HP:0001581)2.31238561
41Gingivitis (HP:0000230)2.30547948
42Metaphyseal cupping (HP:0003021)2.29919353
43Abnormality of the nasal mucosa (HP:0000433)2.29554017
44Recurrent gram-negative bacterial infections (HP:0005420)2.27410933
45Abnormality of the astrocytes (HP:0100707)2.25725489
46Astrocytoma (HP:0009592)2.25725489
47Cellulitis (HP:0100658)2.25504366
48Cervical subluxation (HP:0003308)2.22928787
49Prominent nose (HP:0000448)2.17940616
50Myocardial infarction (HP:0001658)2.17279220
51Missing ribs (HP:0000921)2.16863964
52IgM deficiency (HP:0002850)2.16643783
53Chronic mucocutaneous candidiasis (HP:0002728)2.16525276
54Recurrent cutaneous fungal infections (HP:0011370)2.16525276
55Asymmetric septal hypertrophy (HP:0001670)2.16455264
56High pitched voice (HP:0001620)2.14256605
57Gastrointestinal inflammation (HP:0004386)2.12427853
58Slow saccadic eye movements (HP:0000514)2.12262406
59Vasculitis (HP:0002633)2.10226792
60Elevated erythrocyte sedimentation rate (HP:0003565)2.09341211
61Biliary tract neoplasm (HP:0100574)2.09283416
62Pulmonary infiltrates (HP:0002113)2.09039512
63Abnormality of T cells (HP:0002843)2.09007218
64Ulnar deviation of the wrist (HP:0003049)2.08765175
65Agnosia (HP:0010524)2.08137624
66Malnutrition (HP:0004395)2.08058440
6711 pairs of ribs (HP:0000878)2.07494510
68Increased density of long bones (HP:0006392)2.07479223
69Neuronal loss in central nervous system (HP:0002529)2.06865851
70Thrombocytosis (HP:0001894)2.06629757
71Neurofibrillary tangles (HP:0002185)2.06261289
72Inflammation of the large intestine (HP:0002037)2.03744377
73Persistence of primary teeth (HP:0006335)2.00629441
74Obstructive lung disease (HP:0006536)1.98953880
75Chronic obstructive pulmonary disease (HP:0006510)1.98953880
76Distal lower limb amyotrophy (HP:0008944)1.97919871
77Segmental peripheral demyelination/remyelination (HP:0003481)1.96912163
78Macroorchidism (HP:0000053)1.96419310
79Meningitis (HP:0001287)1.94563675
80Gastrointestinal carcinoma (HP:0002672)1.93766276
81Malignant gastrointestinal tract tumors (HP:0006749)1.93766276
82Broad face (HP:0000283)1.92328110
83Broad palm (HP:0001169)1.91268310
84Hemoptysis (HP:0002105)1.91013678
85Abnormal delayed hypersensitivity skin test (HP:0002963)1.89100304
86Spinal muscular atrophy (HP:0007269)1.88917494
87Purpura (HP:0000979)1.88541114
88Mitral valve prolapse (HP:0001634)1.88378306
89Chronic otitis media (HP:0000389)1.88219602
90Glomerulonephritis (HP:0000099)1.87957505
91Recurrent fungal infections (HP:0002841)1.87736843
92Centrally nucleated skeletal muscle fibers (HP:0003687)1.87000682
93Overlapping toe (HP:0001845)1.86691182
94Axonal loss (HP:0003447)1.86666042
95Interstitial pulmonary disease (HP:0006530)1.86162012
96Eczematoid dermatitis (HP:0000976)1.86027228
97Abnormality of the calcaneus (HP:0008364)1.84897626
98Keratoconjunctivitis sicca (HP:0001097)1.84290607
99Medulloblastoma (HP:0002885)1.84197321
100Increased serum ferritin (HP:0003281)1.84070454
101Restrictive lung disease (HP:0002091)1.83466377
102Thin bony cortex (HP:0002753)1.83374080
103Spondylolisthesis (HP:0003302)1.82633566
104Severe short stature (HP:0003510)1.82355190
105Abnormality of T cell physiology (HP:0011840)1.80887076
106Achilles tendon contracture (HP:0001771)1.80824638
107IgA deficiency (HP:0002720)1.80743261
108Cerebral inclusion bodies (HP:0100314)1.80229585
109Colon cancer (HP:0003003)1.80007424
110Flat acetabular roof (HP:0003180)1.78943100
111Hematochezia (HP:0002573)1.78705100
112Gastrointestinal infarctions (HP:0005244)1.78465059
113Autoimmune thrombocytopenia (HP:0001973)1.78114160
114Verrucae (HP:0200043)1.77667734
115Papilloma (HP:0012740)1.77667734
116Emphysema (HP:0002097)1.76522563
117Bone pain (HP:0002653)1.76394812
118Colitis (HP:0002583)1.76368613
119Disinhibition (HP:0000734)1.75248773
120Vertebral clefting (HP:0008428)1.74897345
121Urinary glycosaminoglycan excretion (HP:0003541)1.73355901
122Mucopolysacchariduria (HP:0008155)1.73355901
123Cutaneous melanoma (HP:0012056)1.72610629
124Upper motor neuron abnormality (HP:0002127)1.72591186
125Bicuspid aortic valve (HP:0001647)1.72518363
126Thoracic kyphosis (HP:0002942)1.72397010
127Radial bowing (HP:0002986)1.72314979
128Mitral regurgitation (HP:0001653)1.71947887
129Bowing of the arm (HP:0006488)1.71334377
130Bowed forearm bones (HP:0003956)1.71334377
131Amyloidosis (HP:0011034)1.71330744
132Global brain atrophy (HP:0002283)1.71064617
133Protrusio acetabuli (HP:0003179)1.70971401
134Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.70736704
135Amaurosis fugax (HP:0100576)1.70726888
136Skin tags (HP:0010609)1.69684173
137Neoplasm of the oral cavity (HP:0100649)1.68391016
138Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.68049658
139Genu recurvatum (HP:0002816)1.68041079
140Abnormality of mucopolysaccharide metabolism (HP:0011020)1.67465993
141Abnormality of polysaccharide metabolism (HP:0011012)1.67465993
142Abnormality of glycosaminoglycan metabolism (HP:0004371)1.67465993
143Abnormality of cells of the lymphoid lineage (HP:0012140)1.67251717
144Increased IgE level (HP:0003212)1.67145162
145Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.67039537
146Cafe-au-lait spot (HP:0000957)1.66597226
147Broad thumb (HP:0011304)1.66324641
148Dilatation of the ascending aorta (HP:0005111)1.66272616
149Supranuclear gaze palsy (HP:0000605)1.66205976
150Abnormality of the endocardium (HP:0004306)1.65799951
151Aortic aneurysm (HP:0004942)1.64072882
152Joint stiffness (HP:0001387)1.63309274
153Sandal gap (HP:0001852)1.62554746
154Aplasia/Hypoplasia of the vertebrae (HP:0008515)1.62503849
155Vertebral hypoplasia (HP:0008417)1.62503849
156Myopathic facies (HP:0002058)1.62285174
157Difficulty climbing stairs (HP:0003551)1.61724932
158Neoplasm of striated muscle (HP:0009728)1.61440911
159Angiofibromas (HP:0010615)1.61437518
160Adenoma sebaceum (HP:0009720)1.61437518
161Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.61104928
162Frequent falls (HP:0002359)1.59464069
163Deviation of the thumb (HP:0009603)1.58901247
164Lymphopenia (HP:0001888)1.58845376
165Increased connective tissue (HP:0009025)1.57776382
166Aneurysm (HP:0002617)1.57686965
167Myelodysplasia (HP:0002863)1.56982049
168Dysostosis multiplex (HP:0000943)1.55425613

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK123.89210683
2EEF2K3.65928375
3TRIB33.32994351
4PKN23.26976369
5PRPF4B3.18418076
6MAP4K13.03397451
7MAP3K102.98874200
8RIPK42.73806161
9ERN12.59634211
10STK102.44802699
11MAP3K132.29740884
12BLK2.24872558
13NEK21.92682978
14TTN1.83908820
15ICK1.82453658
16GRK61.75390496
17JAK31.71986607
18PASK1.67700167
19IRAK41.67467851
20LRRK21.64885627
21RPS6KB21.59051417
22TAOK21.58221209
23CDC42BPA1.52831555
24FLT31.45326087
25EPHB11.44120707
26PTK61.43773682
27CDC71.43610297
28MAP3K111.41362634
29SMG11.39223886
30ALK1.32298181
31ZAP701.29926700
32SCYL21.28948962
33IKBKE1.26733597
34TAOK11.24990101
35MAP3K81.24734166
36CAMK1G1.22942659
37RPS6KA41.20063566
38MTOR1.19368833
39MAP3K11.12063289
40BRD41.11043892
41CSF1R1.06678688
42CAMKK11.06495273
43CDK41.06469883
44FGFR41.06289020
45ITK1.04873661
46HIPK21.02182791
47TXK1.01223400
48MATK0.98389863
49BTK0.95658925
50FES0.94355644
51TGFBR20.94045444
52PAK40.93860578
53DDR20.93816713
54CAMK1D0.93457887
55CDK70.93380643
56TTK0.93195766
57PDGFRA0.92884466
58PIM10.92515356
59MAPK70.92394396
60IRAK30.91549331
61EPHA20.89653299
62FGR0.89248281
63SIK10.88778853
64MAPK120.87991390
65TYK20.87376358
66ATR0.85926492
67NEK90.85905117
68PDPK10.85325726
69MAP2K20.84168260
70MAPKAPK30.83120345
71FGFR30.82764318
72MOS0.82265827
73RPS6KA20.82232727
74CSK0.82127147
75STK40.81498651
76CHUK0.80238510
77CDK60.78661641
78HCK0.78366810
79TBK10.77382293
80MAPK110.77048775
81NME20.76111653
82CHEK10.74424606
83LCK0.73163487
84BMX0.72294855
85RPS6KL10.71361024
86RPS6KC10.71361024
87MAP3K60.71135920
88PAK20.70618025
89GRK70.70398939
90MAP2K30.70095265
91TGFBR10.68587867
92PDK10.67724955
93TESK20.66773819
94IRAK20.65974047
95PDGFRB0.65906308
96JAK10.65853724
97CAMKK20.65637593
98JAK20.62749033
99KIT0.61891616
100LYN0.61758314
101WNK10.61292031
102IKBKB0.61291469
103PIM20.61165347
104MAP3K20.61006651
105CLK10.60921500
106TRPM70.60025542
107RPS6KA60.59173638
108SYK0.58767920
109SGK30.57927280
110CDK20.56960079
111RET0.55711559
112SIK20.55195900
113MAP3K70.54803852
114MAP2K60.54715533
115STK380.54646655
116MARK30.54423508
117TNK20.54420331
118TYRO30.54136530
119MST40.53979304
120KSR20.53091470
121ATM0.52862813
122PTK20.50497451
123PRKCH0.48828162
124RIPK10.48135518
125WNK40.47963572
126STK30.47425456
127PRKD30.47406730
128AURKB0.46859954
129SIK30.46094013
130MELK0.45737043
131MST1R0.45161007
132TAOK30.44300583
133PRKD20.43685212
134MAP3K30.43186057
135PRKCI0.41546308
136MAPKAPK20.41425545
137PNCK0.41263876
138MARK20.40933266
139MAP3K140.40226408
140MAPK10.40210977
141DYRK1B0.40209596
142DYRK30.39011286

Predicted pathways (KEGG)

RankGene SetZ-score
1One carbon pool by folate_Homo sapiens_hsa006702.00655137
2Primary immunodeficiency_Homo sapiens_hsa053401.98861729
3Antigen processing and presentation_Homo sapiens_hsa046121.97713531
4DNA replication_Homo sapiens_hsa030301.94852866
5B cell receptor signaling pathway_Homo sapiens_hsa046621.92317553
6Chronic myeloid leukemia_Homo sapiens_hsa052201.90459559
7Mismatch repair_Homo sapiens_hsa034301.85388419
8Non-homologous end-joining_Homo sapiens_hsa034501.85306420
9Staphylococcus aureus infection_Homo sapiens_hsa051501.81957592
10Acute myeloid leukemia_Homo sapiens_hsa052211.68517716
11Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.60207519
12Base excision repair_Homo sapiens_hsa034101.58026254
13RNA transport_Homo sapiens_hsa030131.51288926
14Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.50903478
15Allograft rejection_Homo sapiens_hsa053301.49980461
16Malaria_Homo sapiens_hsa051441.46131342
17T cell receptor signaling pathway_Homo sapiens_hsa046601.45426816
18Spliceosome_Homo sapiens_hsa030401.41056079
19Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.40157390
20Graft-versus-host disease_Homo sapiens_hsa053321.39780815
21mRNA surveillance pathway_Homo sapiens_hsa030151.39045282
22NF-kappa B signaling pathway_Homo sapiens_hsa040641.35531415
23Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.34649904
24Viral carcinogenesis_Homo sapiens_hsa052031.32860981
25Pancreatic cancer_Homo sapiens_hsa052121.32449997
26mTOR signaling pathway_Homo sapiens_hsa041501.31196769
27Osteoclast differentiation_Homo sapiens_hsa043801.30849800
28Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.30685286
29Autoimmune thyroid disease_Homo sapiens_hsa053201.30019070
30Pertussis_Homo sapiens_hsa051331.29480051
31HTLV-I infection_Homo sapiens_hsa051661.27222201
32Glycosaminoglycan degradation_Homo sapiens_hsa005311.27154031
33Rheumatoid arthritis_Homo sapiens_hsa053231.25758202
34Apoptosis_Homo sapiens_hsa042101.25232680
35Notch signaling pathway_Homo sapiens_hsa043301.21346986
36Small cell lung cancer_Homo sapiens_hsa052221.21099110
37Intestinal immune network for IgA production_Homo sapiens_hsa046721.20932812
38Leishmaniasis_Homo sapiens_hsa051401.18226231
39Measles_Homo sapiens_hsa051621.17470858
40Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.17010075
41Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.16738302
42Toxoplasmosis_Homo sapiens_hsa051451.16400787
43MicroRNAs in cancer_Homo sapiens_hsa052061.15029273
44AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.14786519
45Non-small cell lung cancer_Homo sapiens_hsa052231.14496924
46Neurotrophin signaling pathway_Homo sapiens_hsa047221.13850512
47Leukocyte transendothelial migration_Homo sapiens_hsa046701.13360465
48Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.13350016
49Colorectal cancer_Homo sapiens_hsa052101.12988516
50Cell cycle_Homo sapiens_hsa041101.12571279
51Herpes simplex infection_Homo sapiens_hsa051681.10128196
52Transcriptional misregulation in cancer_Homo sapiens_hsa052021.09885039
53Shigellosis_Homo sapiens_hsa051311.08459391
54Lysine degradation_Homo sapiens_hsa003101.06171634
55Thyroid cancer_Homo sapiens_hsa052161.05271595
56Phagosome_Homo sapiens_hsa041451.02153932
57Adipocytokine signaling pathway_Homo sapiens_hsa049201.00915778
58Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.99077527
59Hepatitis B_Homo sapiens_hsa051610.99049651
60Proteoglycans in cancer_Homo sapiens_hsa052050.97524481
61VEGF signaling pathway_Homo sapiens_hsa043700.97335541
62Type I diabetes mellitus_Homo sapiens_hsa049400.96080678
63Prolactin signaling pathway_Homo sapiens_hsa049170.96043008
64p53 signaling pathway_Homo sapiens_hsa041150.94926212
65Insulin resistance_Homo sapiens_hsa049310.93531537
66Prion diseases_Homo sapiens_hsa050200.93445706
67Hematopoietic cell lineage_Homo sapiens_hsa046400.93362251
68Viral myocarditis_Homo sapiens_hsa054160.92489987
69Jak-STAT signaling pathway_Homo sapiens_hsa046300.91323083
70Central carbon metabolism in cancer_Homo sapiens_hsa052300.91319375
71Epstein-Barr virus infection_Homo sapiens_hsa051690.90580435
72Influenza A_Homo sapiens_hsa051640.90476513
73Legionellosis_Homo sapiens_hsa051340.90097617
74Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.89613700
75Lysosome_Homo sapiens_hsa041420.88695324
76Other glycan degradation_Homo sapiens_hsa005110.88331210
77Adherens junction_Homo sapiens_hsa045200.87252300
78Bladder cancer_Homo sapiens_hsa052190.87149023
79Amoebiasis_Homo sapiens_hsa051460.86786034
80Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.85912513
81Asthma_Homo sapiens_hsa053100.85731896
82Focal adhesion_Homo sapiens_hsa045100.85373990
83GnRH signaling pathway_Homo sapiens_hsa049120.84550193
84Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.83573280
85RNA degradation_Homo sapiens_hsa030180.82122379
86Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.81957283
87Endometrial cancer_Homo sapiens_hsa052130.81588136
88Prostate cancer_Homo sapiens_hsa052150.81054694
89Phospholipase D signaling pathway_Homo sapiens_hsa040720.81014162
90Platelet activation_Homo sapiens_hsa046110.79946641
91Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.78460094
92Fanconi anemia pathway_Homo sapiens_hsa034600.77866029
93Thyroid hormone signaling pathway_Homo sapiens_hsa049190.76379907
94Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.75240366
95Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.74359931
96NOD-like receptor signaling pathway_Homo sapiens_hsa046210.74210111
97African trypanosomiasis_Homo sapiens_hsa051430.73845405
98Toll-like receptor signaling pathway_Homo sapiens_hsa046200.73614281
99Homologous recombination_Homo sapiens_hsa034400.72885990
100Sphingolipid signaling pathway_Homo sapiens_hsa040710.72635656
101Regulation of actin cytoskeleton_Homo sapiens_hsa048100.71192117
102Dorso-ventral axis formation_Homo sapiens_hsa043200.70912899
103Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.70766912
104Nucleotide excision repair_Homo sapiens_hsa034200.69659677
105TNF signaling pathway_Homo sapiens_hsa046680.69484438
106ErbB signaling pathway_Homo sapiens_hsa040120.69025784
107Pathways in cancer_Homo sapiens_hsa052000.68337590
108Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.68326630
109N-Glycan biosynthesis_Homo sapiens_hsa005100.68029576
110Phosphatidylinositol signaling system_Homo sapiens_hsa040700.67889362
111Inositol phosphate metabolism_Homo sapiens_hsa005620.67400372
112Renal cell carcinoma_Homo sapiens_hsa052110.67367747
113Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.67155884
114Chemokine signaling pathway_Homo sapiens_hsa040620.66952212
115RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.66166931
116Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.65478004
117Tuberculosis_Homo sapiens_hsa051520.63593892
118Selenocompound metabolism_Homo sapiens_hsa004500.63548689
119Insulin signaling pathway_Homo sapiens_hsa049100.62166320
120Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.61387095
121HIF-1 signaling pathway_Homo sapiens_hsa040660.61020851
122Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.60961121
123Hepatitis C_Homo sapiens_hsa051600.60217318
124MAPK signaling pathway_Homo sapiens_hsa040100.59587109
125Galactose metabolism_Homo sapiens_hsa000520.58738041
126FoxO signaling pathway_Homo sapiens_hsa040680.58020052
127Type II diabetes mellitus_Homo sapiens_hsa049300.57779840
128Estrogen signaling pathway_Homo sapiens_hsa049150.56792843
129Endocytosis_Homo sapiens_hsa041440.56128841
130Longevity regulating pathway - mammal_Homo sapiens_hsa042110.55495032
131Salmonella infection_Homo sapiens_hsa051320.55448670
132Glioma_Homo sapiens_hsa052140.54864081
133Choline metabolism in cancer_Homo sapiens_hsa052310.49664084
134Sphingolipid metabolism_Homo sapiens_hsa006000.46887316

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