CCAR2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1layer formation in cerebral cortex (GO:0021819)4.60010264
2negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.58555040
3negative regulation of cell killing (GO:0031342)4.58555040
4negative regulation of erythrocyte differentiation (GO:0045647)4.40991664
5negative regulation of mRNA splicing, via spliceosome (GO:0048025)4.27857269
6DNA unwinding involved in DNA replication (GO:0006268)4.22105153
7peptidyl-lysine dimethylation (GO:0018027)4.21604608
8nucleosome disassembly (GO:0006337)4.14375260
9protein-DNA complex disassembly (GO:0032986)4.14375260
10pre-miRNA processing (GO:0031054)3.93018299
113-UTR-mediated mRNA stabilization (GO:0070935)3.86610488
12negative regulation of RNA splicing (GO:0033119)3.83170413
13peptidyl-arginine omega-N-methylation (GO:0035247)3.69351357
14positive regulation of RNA splicing (GO:0033120)3.68720247
15locomotory exploration behavior (GO:0035641)3.63330059
16glucocorticoid receptor signaling pathway (GO:0042921)3.59625384
17adherens junction assembly (GO:0034333)3.59392378
18planar cell polarity pathway involved in neural tube closure (GO:0090179)3.56953925
19mitotic chromosome condensation (GO:0007076)3.52566839
20establishment of nucleus localization (GO:0040023)3.50974905
21synaptic vesicle maturation (GO:0016188)3.48551647
22positive regulation of synapse maturation (GO:0090129)3.45515961
23sodium ion export (GO:0071436)3.45346811
24cell-substrate adherens junction assembly (GO:0007045)3.43604378
25focal adhesion assembly (GO:0048041)3.43604378
26glial cell proliferation (GO:0014009)3.43046394
27peptidyl-arginine methylation (GO:0018216)3.42945294
28peptidyl-arginine N-methylation (GO:0035246)3.42945294
29regulation of nucleobase-containing compound transport (GO:0032239)3.42119457
30negative regulation of histone methylation (GO:0031061)3.41100250
31negative regulation of cell size (GO:0045792)3.41027025
32dosage compensation (GO:0007549)3.40342896
33regulation of translational fidelity (GO:0006450)3.39336586
34regulation of mammary gland epithelial cell proliferation (GO:0033599)3.38010328
35protein localization to endosome (GO:0036010)3.35647100
36apoptotic process involved in morphogenesis (GO:0060561)3.33539568
37regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.32125456
38spliceosomal tri-snRNP complex assembly (GO:0000244)3.29766563
39negative regulation of mRNA processing (GO:0050686)3.29280597
40retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.28537076
41alternative mRNA splicing, via spliceosome (GO:0000380)3.27634478
42histone H3-K36 demethylation (GO:0070544)3.27338114
43regulation of NFAT protein import into nucleus (GO:0051532)3.20364495
44negative regulation of microtubule polymerization (GO:0031115)3.20092225
45regulation of histone H3-K27 methylation (GO:0061085)3.16758726
46embryonic process involved in female pregnancy (GO:0060136)3.14395707
47cytoskeletal anchoring at plasma membrane (GO:0007016)3.12815954
48cellular protein complex localization (GO:0034629)3.12700296
49protein complex localization (GO:0031503)3.08229480
50positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.07881426
51epithelial cell differentiation involved in prostate gland development (GO:0060742)3.07610291
52activation of Rac GTPase activity (GO:0032863)3.07566486
53heterochromatin organization (GO:0070828)3.06216554
54regulation of short-term neuronal synaptic plasticity (GO:0048172)3.06065786
55cell migration in hindbrain (GO:0021535)3.04289682
56negative regulation of mRNA metabolic process (GO:1903312)3.03166532
57maternal placenta development (GO:0001893)3.02685514
58pentose-phosphate shunt (GO:0006098)3.01710874
59translesion synthesis (GO:0019985)2.98879209
60protein retention in ER lumen (GO:0006621)2.98760368
61regulation of glucose import in response to insulin stimulus (GO:2001273)2.97437875
62intracellular estrogen receptor signaling pathway (GO:0030520)2.95908126
63mannose metabolic process (GO:0006013)2.95662524
64proline biosynthetic process (GO:0006561)2.94738470
65regulation of gamma-delta T cell differentiation (GO:0045586)2.94072580
66maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.93299160
67stress granule assembly (GO:0034063)2.92069760
68positive regulation of histone deacetylation (GO:0031065)2.91789001
69protein export from nucleus (GO:0006611)2.91728528
70regulation of early endosome to late endosome transport (GO:2000641)2.91384071
71nuclear pore complex assembly (GO:0051292)2.90596553
72G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.90010399
73regulation of synapse structural plasticity (GO:0051823)2.89959330
74synaptic vesicle docking involved in exocytosis (GO:0016081)2.86929300
75positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145)2.85383011
76response to laminar fluid shear stress (GO:0034616)2.84639061
77mRNA stabilization (GO:0048255)2.84615449
78RNA stabilization (GO:0043489)2.84615449
79positive regulation of dendritic spine morphogenesis (GO:0061003)2.80522873
80regulation of ARF protein signal transduction (GO:0032012)2.80482658
81regulation of chromatin binding (GO:0035561)2.79702954
82positive regulation of gene expression, epigenetic (GO:0045815)2.78378215
83positive regulation of gamma-delta T cell activation (GO:0046645)2.76703250
84positive thymic T cell selection (GO:0045059)2.76014565
85positive regulation of dendrite morphogenesis (GO:0050775)2.75617301
86pore complex assembly (GO:0046931)2.75573760
87corticosteroid receptor signaling pathway (GO:0031958)2.75504113
88positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling2.75396328
89dendritic spine morphogenesis (GO:0060997)2.74276881
90modulation by symbiont of host cellular process (GO:0044068)2.73570242
91clathrin coat assembly (GO:0048268)2.72578274
92modulation by virus of host process (GO:0019054)2.71130997
93regulation of mRNA stability (GO:0043488)2.71039092
94regulation of translational termination (GO:0006449)2.69555404
95mRNA splice site selection (GO:0006376)2.68818942
96regulation of ARF GTPase activity (GO:0032312)2.65582213
97cellular hyperosmotic response (GO:0071474)2.65431695
98stress fiber assembly (GO:0043149)2.64883278
99histone lysine demethylation (GO:0070076)2.64866800
100regulation of histone H3-K9 methylation (GO:0051570)2.64819607
101signal complex assembly (GO:0007172)2.64628780
102DNA topological change (GO:0006265)2.64446962
103cell-substrate junction assembly (GO:0007044)2.63766867
104response to epidermal growth factor (GO:0070849)2.62521371
105positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.62174138
106axonal fasciculation (GO:0007413)2.61833700
107barbed-end actin filament capping (GO:0051016)2.61759939
108activation of protein kinase A activity (GO:0034199)2.61479277
109cerebellar Purkinje cell differentiation (GO:0021702)2.59857824
110nuclear pore organization (GO:0006999)2.59390240
111NADPH regeneration (GO:0006740)2.58710045
112positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.58347821
113activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.58111460
114regulation of RNA stability (GO:0043487)2.57728220
115negative thymic T cell selection (GO:0045060)2.56452560
116positive regulation of nuclease activity (GO:0032075)2.55752655
117pinocytosis (GO:0006907)2.55180465
118negative regulation of organelle assembly (GO:1902116)2.55001541
119positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.52819080
120positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.52765826
121embryonic foregut morphogenesis (GO:0048617)2.52508386
122negative T cell selection (GO:0043383)2.52487266
123histone demethylation (GO:0016577)2.52405939
124response to pheromone (GO:0019236)2.51858149
125histone H4 deacetylation (GO:0070933)2.50451396
126negative regulation of gene expression, epigenetic (GO:0045814)2.49666743
127DNA duplex unwinding (GO:0032508)2.49209273
128semaphorin-plexin signaling pathway (GO:0071526)2.48607080
129cytoplasmic mRNA processing body assembly (GO:0033962)2.47929237
130cerebellar Purkinje cell layer development (GO:0021680)2.47239841
131negative regulation of histone modification (GO:0031057)2.46258095
132histone arginine methylation (GO:0034969)2.45924112
133regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway 2.44912670
134positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling2.44912670
135positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.44904332
136exploration behavior (GO:0035640)2.43828093
137histone H2A acetylation (GO:0043968)2.43786408
138protein localization to kinetochore (GO:0034501)2.43641254
139regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.43375751
140DNA geometric change (GO:0032392)2.43265940
141histone H3-K9 demethylation (GO:0033169)2.42663406
142cellular response to epidermal growth factor stimulus (GO:0071364)2.42582828
143NLS-bearing protein import into nucleus (GO:0006607)2.41173652
144histone H4-K16 acetylation (GO:0043984)2.40857665
145histone H4 acetylation (GO:0043967)2.39563516
146mitotic sister chromatid cohesion (GO:0007064)2.39498128
147glucose catabolic process (GO:0006007)2.39468758
148modulation by virus of host morphology or physiology (GO:0019048)2.38948197
149regulation of RNA export from nucleus (GO:0046831)2.38896516
150regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.38410944
151activation of MAPKKK activity (GO:0000185)2.37987622
152regulation of gamma-delta T cell activation (GO:0046643)2.37429229
153negative regulation of myotube differentiation (GO:0010832)2.37356680
154insulin-like growth factor receptor signaling pathway (GO:0048009)2.36893824
155regulation of type I interferon-mediated signaling pathway (GO:0060338)2.35083350
156positive T cell selection (GO:0043368)2.34792573
157trophectodermal cell differentiation (GO:0001829)2.34288484
158thymic T cell selection (GO:0045061)2.33907888
159COPI coating of Golgi vesicle (GO:0048205)2.33569111
160Golgi transport vesicle coating (GO:0048200)2.33569111
161regulation of defense response to virus by virus (GO:0050690)2.33536407
162regulation of nuclease activity (GO:0032069)2.33372982
163regulation of sister chromatid cohesion (GO:0007063)2.33302897
164formation of translation preinitiation complex (GO:0001731)2.32711698

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.10300186
2MYC_22102868_ChIP-Seq_BL_Human4.50334162
3FOXM1_23109430_ChIP-Seq_U2OS_Human3.65472432
4EGR1_19374776_ChIP-ChIP_THP-1_Human3.41418066
5EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse3.15755310
6NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.97954102
7ZFP281_18757296_ChIP-ChIP_E14_Mouse2.76767935
8VDR_21846776_ChIP-Seq_THP-1_Human2.74702115
9KDM2B_26808549_Chip-Seq_DND41_Human2.73590622
10STAT6_21828071_ChIP-Seq_BEAS2B_Human2.66070164
11TCF7_22412390_ChIP-Seq_EML_Mouse2.65936024
12KDM2B_26808549_Chip-Seq_SUP-B15_Human2.60360454
13KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.39642942
14TP63_17297297_ChIP-ChIP_HaCaT_Human2.34625360
15KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.32888627
16ZFP281_27345836_Chip-Seq_ESCs_Mouse2.28839564
17CIITA_25753668_ChIP-Seq_RAJI_Human2.21779354
18DMRT1_23473982_ChIP-Seq_TESTES_Mouse2.11957925
19EZH2_22144423_ChIP-Seq_EOC_Human2.09715273
20ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.09293319
21THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.04830475
22KDM2B_26808549_Chip-Seq_JURKAT_Human2.03594852
23LXR_22292898_ChIP-Seq_THP-1_Human1.99322730
24MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.97778621
25ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.97368587
26NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.96404400
27WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.95714630
28RARB_27405468_Chip-Seq_BRAIN_Mouse1.95395487
29EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.94915304
30CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.93823526
31UTX_26944678_Chip-Seq_JUKART_Human1.92111822
32HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.88893325
33KDM2B_26808549_Chip-Seq_K562_Human1.85726905
34TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.81619545
35EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.80782488
36CLOCK_20551151_ChIP-Seq_293T_Human1.76272666
37STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.68710050
38ELK3_25401928_ChIP-Seq_HUVEC_Human1.68095841
39RARG_19884340_ChIP-ChIP_MEFs_Mouse1.65274242
40MAF_26560356_Chip-Seq_TH1_Human1.63822394
41CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.62223251
42TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.60630567
43MYC_18555785_ChIP-Seq_MESCs_Mouse1.54431210
44E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.52919828
45EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.50123753
46DROSHA_22980978_ChIP-Seq_HELA_Human1.48894312
47CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.48450741
48E2F4_17652178_ChIP-ChIP_JURKAT_Human1.48028395
49DNAJC2_21179169_ChIP-ChIP_NT2_Human1.46400636
50TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.43740361
51KLF4_18555785_ChIP-Seq_MESCs_Mouse1.41689645
52ZNF263_19887448_ChIP-Seq_K562_Human1.40649557
53GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.40244579
54SCL_19346495_ChIP-Seq_HPC-7_Human1.38328243
55P68_20966046_ChIP-Seq_HELA_Human1.37963578
56KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.37836133
57PKCTHETA_26484144_Chip-Seq_BREAST_Human1.37784844
58KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.37233197
59CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.35111492
60RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.34644273
61VDR_24763502_ChIP-Seq_THP-1_Human1.33172193
62TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.30722287
63P300_27058665_Chip-Seq_ZR-75-30cells_Human1.28641798
64CREB1_26743006_Chip-Seq_LNCaP_Human1.28347416
65PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.24879640
66XRN2_22483619_ChIP-Seq_HELA_Human1.24770359
67CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.23470161
68TET1_21451524_ChIP-Seq_MESCs_Mouse1.23330768
69TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.19327582
70TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.19098635
71BRD4_27068464_Chip-Seq_AML-cells_Mouse1.18688358
72SRY_22984422_ChIP-ChIP_TESTIS_Rat1.16501718
73KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.16465959
74SMC4_20622854_ChIP-Seq_HELA_Human1.16200918
75DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.14782198
76SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.14537682
77ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.13937729
78POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.13218925
79SPI1_23127762_ChIP-Seq_K562_Human1.13029887
80REST_18959480_ChIP-ChIP_MESCs_Mouse1.12725305
81DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.12078445
82OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.11913902
83NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.11178155
84GATA1_22383799_ChIP-Seq_G1ME_Mouse1.11109314
85NCOR1_26117541_ChIP-Seq_K562_Human1.09933107
86STAT3_1855785_ChIP-Seq_MESCs_Mouse1.08087760
87MAF_26560356_Chip-Seq_TH2_Human1.08059652
88MYC_18358816_ChIP-ChIP_MESCs_Mouse1.06708718
89ELF1_20517297_ChIP-Seq_JURKAT_Human1.06621479
90FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.06219007
91HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.05884578
92ATF3_27146783_Chip-Seq_COLON_Human1.05118593
93MYC_19030024_ChIP-ChIP_MESCs_Mouse1.04035795
94KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.03206417
95NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.02561742
96SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.02532684
97POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.01466988
98ESR1_15608294_ChIP-ChIP_MCF-7_Human1.01113640
99MYB_26560356_Chip-Seq_TH2_Human1.00581838
100UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.00259854
101NELFA_20434984_ChIP-Seq_ESCs_Mouse0.99744331
102ERG_21242973_ChIP-ChIP_JURKAT_Human0.99593876
103IKZF1_21737484_ChIP-ChIP_HCT116_Human0.99298932
104CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.99144573
105FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.98501543
106RACK7_27058665_Chip-Seq_MCF-7_Human0.98476099
107TP53_22127205_ChIP-Seq_IMR90_Human0.98046314
108RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.97692796
109E2F1_21310950_ChIP-Seq_MCF-7_Human0.97524220
110SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.97437960
111NANOG_21062744_ChIP-ChIP_HESCs_Human0.97240224
112REST_21632747_ChIP-Seq_MESCs_Mouse0.97064780
113SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.96432061
114MYCN_18555785_ChIP-Seq_MESCs_Mouse0.96380718
115MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.96317355
116FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.95901392
117TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.95350422
118MYC_19079543_ChIP-ChIP_MESCs_Mouse0.95137475
119HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.94562902
120RUNX1_27514584_Chip-Seq_MCF-7_Human0.94358249
121VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.94348943
122SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.93725994
123TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.93572900
124ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.93268387
125CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.92823132
126CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.92561315
127NANOG_18555785_ChIP-Seq_MESCs_Mouse0.92502470
128MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.92496967
129MYB_26560356_Chip-Seq_TH1_Human0.92048737
130ZFX_18555785_ChIP-Seq_MESCs_Mouse0.90099866
131NFIB_24661679_ChIP-Seq_LUNG_Mouse0.89948502
132PHF8_20622854_ChIP-Seq_HELA_Human0.89266819
133RING1B_27294783_Chip-Seq_ESCs_Mouse0.88474275
134FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.88457413
135SA1_27219007_Chip-Seq_ERYTHROID_Human0.87971067
136CTCF_27219007_Chip-Seq_ERYTHROID_Human0.87858378
137RUNX1_22412390_ChIP-Seq_EML_Mouse0.85772447
138KDM5A_27292631_Chip-Seq_BREAST_Human0.85530858

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.34778745
2MP0000569_abnormal_digit_pigmentation3.28437912
3MP0005451_abnormal_body_composition2.89109455
4MP0008961_abnormal_basal_metabolism2.65441293
5MP0005423_abnormal_somatic_nervous2.54540159
6MP0000537_abnormal_urethra_morphology2.45293065
7MP0002877_abnormal_melanocyte_morpholog2.45010403
8MP0002653_abnormal_ependyma_morphology2.40419098
9MP0005076_abnormal_cell_differentiation2.38444299
10MP0010234_abnormal_vibrissa_follicle2.34514036
11MP0008260_abnormal_autophagy2.32843717
12MP0005058_abnormal_lysosome_morphology2.21411489
13MP0004185_abnormal_adipocyte_glucose2.14328942
14MP0003635_abnormal_synaptic_transmissio2.08631781
15MP0003566_abnormal_cell_adhesion2.07719413
16MP0003705_abnormal_hypodermis_morpholog2.00577103
17MP0003122_maternal_imprinting1.97291226
18MP0003123_paternal_imprinting1.96101573
19MP0003283_abnormal_digestive_organ1.93457013
20MP0004811_abnormal_neuron_physiology1.90990378
21MP0003121_genomic_imprinting1.87163955
22MP0003787_abnormal_imprinting1.85230432
23MP0010352_gastrointestinal_tract_polyps1.78604845
24MP0008438_abnormal_cutaneous_collagen1.77679119
25MP0003300_gastrointestinal_ulcer1.77627972
26MP0003091_abnormal_cell_migration1.76527626
27MP0002009_preneoplasia1.75189916
28MP0004808_abnormal_hematopoietic_stem1.74911782
29MP0005409_darkened_coat_color1.73736418
30MP0000778_abnormal_nervous_system1.72780479
31MP0001730_embryonic_growth_arrest1.72238952
32MP0003453_abnormal_keratinocyte_physiol1.65257652
33MP0002909_abnormal_adrenal_gland1.65069234
34MP0002063_abnormal_learning/memory/cond1.61922824
35MP0001849_ear_inflammation1.61733279
36MP0005187_abnormal_penis_morphology1.59664962
37MP0009278_abnormal_bone_marrow1.54256729
38MP0004858_abnormal_nervous_system1.50606593
39MP0002396_abnormal_hematopoietic_system1.48461977
40MP0003763_abnormal_thymus_physiology1.46213464
41MP0003111_abnormal_nucleus_morphology1.45446926
42MP0003861_abnormal_nervous_system1.44805362
43MP0002084_abnormal_developmental_patter1.44329002
44MP0002234_abnormal_pharynx_morphology1.43713818
45MP0003119_abnormal_digestive_system1.42424483
46MP0003115_abnormal_respiratory_system1.40818054
47MP0005257_abnormal_intraocular_pressure1.40490085
48MP0001348_abnormal_lacrimal_gland1.39737256
49MP0000955_abnormal_spinal_cord1.38945926
50MP0002796_impaired_skin_barrier1.37921977
51MP0004947_skin_inflammation1.35036941
52MP0000490_abnormal_crypts_of1.34483732
53MP0000703_abnormal_thymus_morphology1.33400059
54MP0008569_lethality_at_weaning1.32975398
55MP0005666_abnormal_adipose_tissue1.31335415
56MP0003077_abnormal_cell_cycle1.30334475
57MP0004197_abnormal_fetal_growth/weight/1.29684599
58MP0000858_altered_metastatic_potential1.29044345
59MP0005621_abnormal_cell_physiology1.28489886
60MP0010094_abnormal_chromosome_stability1.28157620
61MP0003436_decreased_susceptibility_to1.27541066
62MP0004233_abnormal_muscle_weight1.27471638
63MP0000678_abnormal_parathyroid_gland1.25697744
64MP0002152_abnormal_brain_morphology1.23050008
65MP0002089_abnormal_postnatal_growth/wei1.22882557
66MP0002184_abnormal_innervation1.22804852
67MP0005623_abnormal_meninges_morphology1.22598452
68MP0000733_abnormal_muscle_development1.22182883
69MP0000350_abnormal_cell_proliferation1.18954281
70MP0004264_abnormal_extraembryonic_tissu1.17801067
71MP0009333_abnormal_splenocyte_physiolog1.16951527
72MP0006054_spinal_hemorrhage1.16324304
73MP0002085_abnormal_embryonic_tissue1.16084582
74MP0003172_abnormal_lysosome_physiology1.15180902
75MP0009780_abnormal_chondrocyte_physiolo1.15153955
76MP0004270_analgesia1.13884166
77MP0008770_decreased_survivor_rate1.12668562
78MP0005501_abnormal_skin_physiology1.12356231
79MP0002080_prenatal_lethality1.11194875
80MP0010030_abnormal_orbit_morphology1.10995845
81MP0001697_abnormal_embryo_size1.09536960
82MP0008057_abnormal_DNA_replication1.09118246
83MP0003329_amyloid_beta_deposits1.07285381
84MP0009672_abnormal_birth_weight1.06929944
85MP0005375_adipose_tissue_phenotype1.05878443
86MP0003303_peritoneal_inflammation1.05762083
87MP0005499_abnormal_olfactory_system1.04891540
88MP0005394_taste/olfaction_phenotype1.04891540
89MP0000534_abnormal_ureter_morphology1.04685104
90MP0003191_abnormal_cellular_cholesterol1.02492019
91MP0002249_abnormal_larynx_morphology1.01489166
92MP0009840_abnormal_foam_cell0.99960004
93MP0000313_abnormal_cell_death0.99182946
94MP0010630_abnormal_cardiac_muscle0.98798654
95MP0000428_abnormal_craniofacial_morphol0.98217088
96MP0003942_abnormal_urinary_system0.97671680
97MP0002398_abnormal_bone_marrow0.97547463
98MP0002086_abnormal_extraembryonic_tissu0.97022673
99MP0003221_abnormal_cardiomyocyte_apopto0.96562050
100MP0002060_abnormal_skin_morphology0.96480352
101MP0001672_abnormal_embryogenesis/_devel0.96099897
102MP0005380_embryogenesis_phenotype0.96099897
103MP0004957_abnormal_blastocyst_morpholog0.95210646
104MP0009745_abnormal_behavioral_response0.94798264
105MP0002882_abnormal_neuron_morphology0.94340486
106MP0010307_abnormal_tumor_latency0.93703308
107MP0000631_abnormal_neuroendocrine_gland0.93139232
108MP0008932_abnormal_embryonic_tissue0.93066793
109MP0003984_embryonic_growth_retardation0.92497773
110MP0002088_abnormal_embryonic_growth/wei0.92051731
111MP0008007_abnormal_cellular_replicative0.91755364
112MP0003890_abnormal_embryonic-extraembry0.91181508
113MP0002081_perinatal_lethality0.90643081
114MP0000751_myopathy0.90538889
115MP0000747_muscle_weakness0.90018286
116MP0002064_seizures0.89797753
117MP0005384_cellular_phenotype0.89592122
118MP0003866_abnormal_defecation0.87455346
119MP0009703_decreased_birth_body0.84518157
120MP0002557_abnormal_social/conspecific_i0.84369017
121MP0009053_abnormal_anal_canal0.83850716
122MP0002925_abnormal_cardiovascular_devel0.82621111
123MP0000465_gastrointestinal_hemorrhage0.82565062
124MP0009931_abnormal_skin_appearance0.82086420
125MP0003385_abnormal_body_wall0.81204746
126MP0005023_abnormal_wound_healing0.80933738
127MP0002572_abnormal_emotion/affect_behav0.80441730
128MP0000759_abnormal_skeletal_muscle0.79989725
129MP0003693_abnormal_embryo_hatching0.79386604
130MP0004272_abnormal_basement_membrane0.79293685
131MP0001346_abnormal_lacrimal_gland0.78987082
132MP0000477_abnormal_intestine_morphology0.78868301
133MP0001545_abnormal_hematopoietic_system0.78225365
134MP0005397_hematopoietic_system_phenotyp0.78225365
135MP0003183_abnormal_peptide_metabolism0.77184942
136MP0003634_abnormal_glial_cell0.76356911
137MP0001915_intracranial_hemorrhage0.75952322
138MP0004087_abnormal_muscle_fiber0.75810859
139MP0002998_abnormal_bone_remodeling0.74297783
140MP0001216_abnormal_epidermal_layer0.73869223
141MP0003935_abnormal_craniofacial_develop0.73553264
142MP0002092_abnormal_eye_morphology0.73145319
143MP0008877_abnormal_DNA_methylation0.72983333
144MP0003880_abnormal_central_pattern0.72601719
145MP0002282_abnormal_trachea_morphology0.71515942
146MP0000003_abnormal_adipose_tissue0.71383109
147MP0000566_synostosis0.71272391
148MP0010769_abnormal_survival0.70185323
149MP0004885_abnormal_endolymph0.68998711

Predicted human phenotypes

RankGene SetZ-score
1Hyperacusis (HP:0010780)4.82947227
2Elfin facies (HP:0004428)3.74046286
3Insomnia (HP:0100785)3.73235480
4Renal duplication (HP:0000075)3.42774805
5Pointed chin (HP:0000307)3.37318810
6Abnormality of the lower motor neuron (HP:0002366)3.37311612
7Short 4th metacarpal (HP:0010044)3.36058958
8Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.36058958
9Renovascular hypertension (HP:0100817)3.34733758
10Overriding aorta (HP:0002623)3.09370983
11Ependymoma (HP:0002888)3.08376140
12Amyotrophic lateral sclerosis (HP:0007354)2.98538190
13Neoplasm of the heart (HP:0100544)2.92404570
14Broad face (HP:0000283)2.83033204
15Increased nuchal translucency (HP:0010880)2.80501177
16Ulnar bowing (HP:0003031)2.80148117
17Obstructive sleep apnea (HP:0002870)2.75848626
18Heterotopia (HP:0002282)2.74913841
19Astrocytoma (HP:0009592)2.73537178
20Abnormality of the astrocytes (HP:0100707)2.73537178
21Abnormality of the 4th metacarpal (HP:0010012)2.71469468
22Macroorchidism (HP:0000053)2.70570452
23Protrusio acetabuli (HP:0003179)2.60222795
24Disproportionate tall stature (HP:0001519)2.56650809
25Distal lower limb amyotrophy (HP:0008944)2.54434597
26Asymmetry of the thorax (HP:0001555)2.52352031
27Obsessive-compulsive behavior (HP:0000722)2.52181719
28Premature rupture of membranes (HP:0001788)2.50991757
29Bowel diverticulosis (HP:0005222)2.50512452
30Flat cornea (HP:0007720)2.45879373
31Long palpebral fissure (HP:0000637)2.43804093
32Ankyloglossia (HP:0010296)2.43310476
33Cerebral aneurysm (HP:0004944)2.42230697
34Centrally nucleated skeletal muscle fibers (HP:0003687)2.35138810
35Abnormality of oral frenula (HP:0000190)2.33005446
36Urinary urgency (HP:0000012)2.31045619
37Turricephaly (HP:0000262)2.29510126
38Sacral dimple (HP:0000960)2.29341939
39Annular pancreas (HP:0001734)2.23928843
40Enlarged penis (HP:0000040)2.22961365
41Achilles tendon contracture (HP:0001771)2.17734614
42Flat acetabular roof (HP:0003180)2.16069111
43Lymphangioma (HP:0100764)2.12528876
44Visual hallucinations (HP:0002367)2.11970027
45Shallow orbits (HP:0000586)2.09471027
46Broad distal phalanx of finger (HP:0009836)2.08244766
47Lower limb amyotrophy (HP:0007210)2.07137278
48Pelvic girdle muscle weakness (HP:0003749)2.06806473
49Spinal cord lesions (HP:0100561)2.05818491
50Syringomyelia (HP:0003396)2.05818491
51Abnormality of the distal phalanx of the thumb (HP:0009617)2.05477932
52Increased connective tissue (HP:0009025)2.03616612
53Impaired vibration sensation in the lower limbs (HP:0002166)2.03365824
54Papilledema (HP:0001085)2.03028348
55Trigonocephaly (HP:0000243)2.02808210
56Abnormality of ocular smooth pursuit (HP:0000617)2.02423260
57Arnold-Chiari malformation (HP:0002308)2.01539599
58Cellulitis (HP:0100658)1.99588388
59Resting tremor (HP:0002322)1.99287222
60Abnormality of the diencephalon (HP:0010662)1.99022180
61Metaphyseal cupping (HP:0003021)1.98557037
62Shoulder girdle muscle weakness (HP:0003547)1.98032931
63Vertebral compression fractures (HP:0002953)1.96154066
64Impaired smooth pursuit (HP:0007772)1.95866133
65Subacute progressive viral hepatitis (HP:0006572)1.94450747
66Dysmetric saccades (HP:0000641)1.94449016
67Attention deficit hyperactivity disorder (HP:0007018)1.93839572
68Basal cell carcinoma (HP:0002671)1.93798806
69Thin bony cortex (HP:0002753)1.93435517
70Medulloblastoma (HP:0002885)1.92347483
71Megalocornea (HP:0000485)1.91695118
72Broad palm (HP:0001169)1.91564922
73Hand muscle atrophy (HP:0009130)1.90431840
74Cerebral inclusion bodies (HP:0100314)1.89131643
75Fibrous tissue neoplasm (HP:0012316)1.88297466
76Biconcave vertebral bodies (HP:0004586)1.88239819
77Abnormality of the thoracic spine (HP:0100711)1.87400000
78Peripheral hypomyelination (HP:0007182)1.87216929
79Cutis marmorata (HP:0000965)1.84774509
80Thin ribs (HP:0000883)1.84526670
81Mitral regurgitation (HP:0001653)1.84460816
82Abnormality of the Achilles tendon (HP:0005109)1.84322095
83Hemiplegia (HP:0002301)1.84105991
84Increased density of long bones (HP:0006392)1.83812841
85Progressive external ophthalmoplegia (HP:0000590)1.82912451
86Verrucae (HP:0200043)1.82747053
87Papilloma (HP:0012740)1.82747053
88Fibroma (HP:0010614)1.82403125
89Depression (HP:0000716)1.82055491
90Dislocated radial head (HP:0003083)1.81626389
91Angiofibromas (HP:0010615)1.81093161
92Adenoma sebaceum (HP:0009720)1.81093161
93Glioma (HP:0009733)1.80574955
94Pseudobulbar signs (HP:0002200)1.80202370
95Supranuclear gaze palsy (HP:0000605)1.80089181
96Upper limb amyotrophy (HP:0009129)1.80072826
97Distal upper limb amyotrophy (HP:0007149)1.80072826
98Abnormality of the intervertebral disk (HP:0005108)1.79034999
99Bladder diverticulum (HP:0000015)1.78419083
100Apathy (HP:0000741)1.77588587
101Abnormality of the fingertips (HP:0001211)1.77353565
102Ankle clonus (HP:0011448)1.76676072
103Segmental peripheral demyelination/remyelination (HP:0003481)1.76450382
104High pitched voice (HP:0001620)1.76254468
105Back pain (HP:0003418)1.75182884
106Atrophy/Degeneration involving motor neurons (HP:0007373)1.74791837
107High anterior hairline (HP:0009890)1.74696387
108Recurrent bronchitis (HP:0002837)1.74651794
109Hallux valgus (HP:0001822)1.74345163
110Long eyelashes (HP:0000527)1.74133229
111Selective tooth agenesis (HP:0001592)1.73956254
112Abnormality of the calcaneus (HP:0008364)1.73820972
113Spina bifida occulta (HP:0003298)1.73661213
114Abnormality of the hip-girdle musculature (HP:0001445)1.73508466
115Abnormality of the musculature of the pelvis (HP:0001469)1.73508466
116Neuronal loss in central nervous system (HP:0002529)1.73418647
117Urethral obstruction (HP:0000796)1.72847148
118Increased variability in muscle fiber diameter (HP:0003557)1.72027207
119Deviation of the hallux (HP:0010051)1.71062481
120Precocious puberty (HP:0000826)1.70691995
121Volvulus (HP:0002580)1.70366660
122Genu recurvatum (HP:0002816)1.69800104
123Termporal pattern (HP:0011008)1.68667876
124Insidious onset (HP:0003587)1.68667876
125Difficulty climbing stairs (HP:0003551)1.68639633
126Cholecystitis (HP:0001082)1.68535095
127Abnormal gallbladder physiology (HP:0012438)1.68535095
128Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.67817145
129Hammertoe (HP:0001765)1.67278420
130Diminished motivation (HP:0000745)1.66972493
131Patellar dislocation (HP:0002999)1.66915001
132Nasal polyposis (HP:0100582)1.66647806
133Deep palmar crease (HP:0006191)1.66098557
134Truncal obesity (HP:0001956)1.66067533
135Abnormality of the radial head (HP:0003995)1.65700744
136Vertebral arch anomaly (HP:0008438)1.64586438
137Hypercortisolism (HP:0001578)1.64135894
138Progressive muscle weakness (HP:0003323)1.63662257
139Bowel incontinence (HP:0002607)1.63625546
140Skin tags (HP:0010609)1.63259268
141Flared metaphyses (HP:0003015)1.63142228
142Distal lower limb muscle weakness (HP:0009053)1.62890500
143Cervical subluxation (HP:0003308)1.62712175
144Reticulocytosis (HP:0001923)1.61721492
145Myokymia (HP:0002411)1.61699653
146Advanced eruption of teeth (HP:0006288)1.61630234
147Mitral valve prolapse (HP:0001634)1.61282905
148Trismus (HP:0000211)1.60827873
149Deviation of the thumb (HP:0009603)1.60333236
150Aneurysm (HP:0002617)1.60235557
151Short nail (HP:0001799)1.60153366
152Limb-girdle muscle atrophy (HP:0003797)1.59896624
153Intellectual disability, profound (HP:0002187)1.59855900
154Neoplasm of the oral cavity (HP:0100649)1.59844445
155Abnormality of skeletal muscle fiber size (HP:0012084)1.59433842
156Abnormality of the salivary glands (HP:0010286)1.59122986
157Inappropriate behavior (HP:0000719)1.58191174
158Premature skin wrinkling (HP:0100678)1.57549020
159Bronchomalacia (HP:0002780)1.56983810
160Thoracic kyphosis (HP:0002942)1.56905574
161Polygenic inheritance (HP:0010982)1.56868692
162Long toe (HP:0010511)1.56782214
163Wormian bones (HP:0002645)1.56628568
164Striae distensae (HP:0001065)1.56540777
165Dilatation of the ascending aorta (HP:0005111)1.56432911
166Neoplasm of striated muscle (HP:0009728)1.56431897
167Urinary bladder sphincter dysfunction (HP:0002839)1.55805402
168Hemorrhage of the eye (HP:0011885)1.55389802

Predicted kinase interactions (KEA)

RankGene SetZ-score
1SMG14.16710813
2EEF2K4.12176947
3TRIB33.79405736
4MAP3K103.68102472
5PRPF4B3.54662088
6PKN23.48581605
7SIK22.35957137
8MARK12.10432775
9RIPK12.09580670
10MAP3K91.89935781
11SCYL21.89601259
12TYRO31.87383117
13KSR11.86152020
14PRKD31.85421275
15ICK1.83065572
16PTK61.76056925
17CDC71.69485204
18MAP4K11.65177495
19ALK1.63438563
20PAK61.53574765
21IRAK31.51555190
22PDGFRA1.50964074
23KSR21.49898534
24CDK121.45494375
25NTRK21.41661358
26NEK21.37803711
27LATS21.37738102
28TGFBR11.35354614
29BRD41.35290145
30PASK1.34186054
31MINK11.30606861
32NEK11.28778970
33GRK61.23597443
34MAP2K31.21815039
35CAMKK11.21469458
36UHMK11.13988302
37NTRK31.13464617
38CAMK1G1.06612791
39MAP3K71.05673309
40LRRK21.05551546
41NME21.04292681
42PAK41.00470348
43RET0.99850594
44MAP3K40.98757811
45SIK10.96600699
46RPS6KA20.96517068
47BRSK10.96377480
48TAOK10.95271382
49ERBB20.95028503
50TAOK20.94996487
51EPHB10.94577222
52DAPK10.93763603
53TESK20.93468940
54DAPK20.92690912
55TTN0.89906140
56SIK30.89513152
57MARK20.88975777
58MTOR0.88826054
59EPHA20.86688479
60PRKCH0.84970824
61TESK10.83583106
62CDK70.83330228
63ERN10.80310907
64MAP3K140.79261240
65ERBB30.78904659
66FGFR10.75922886
67FGFR20.75423858
68MAPK110.74401726
69FGFR40.72493339
70FES0.71391616
71MAP3K10.70173985
72RPS6KB20.70038862
73DYRK1B0.69344396
74PRKD20.68899612
75CDK40.68843357
76CAMK1D0.67154321
77CDK50.66165717
78HIPK20.65882805
79RIPK40.65861932
80CDK150.64401238
81CDK180.63260245
82CDK90.62786433
83FGFR30.62086828
84ARAF0.61597301
85BMX0.61230838
86PAK20.61085256
87RPS6KL10.60863275
88RPS6KC10.60863275
89CDK11A0.59675038
90MAP3K60.59477339
91ILK0.58399740
92BTK0.58295334
93* ATR0.57258837
94TSSK60.56862295
95LMTK20.56663053
96PDPK10.55854887
97CHEK10.55497538
98STK100.53927954
99ZAP700.53833642
100CDK20.51673126
101ITK0.51258491
102CDK140.51173903
103CDK60.47836529
104MAP3K110.47464501
105MAPK90.47259898
106EPHA30.47073724
107DYRK30.46402101
108TTK0.46386478
109IRAK20.46385502
110CLK10.46294965
111SYK0.46075662
112MAP2K20.46005785
113NTRK10.45790138
114MAP3K80.45128466
115PDGFRB0.44874670
116BRAF0.43491369
117JAK30.43224572
118MAP3K30.42903143
119FYN0.42570261
120RPS6KA10.42350015
121DDR20.42256899
122MAPK100.42029187
123SRPK10.40801286
124HCK0.40477059
125MAPK80.39664028
126EPHB20.39602603
127STK110.39079327
128CAMK40.39036494
129TNK20.38154381
130PTK20.37735365
131SGK30.37649697
132CDC42BPA0.37620591
133TBK10.37350632
134PAK30.37328598
135MAP3K130.36844071
136CSF1R0.36115911
137AKT20.33362655
138TYK20.33247939
139RPS6KA60.31842021

Predicted pathways (KEGG)

RankGene SetZ-score
1Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.44007092
2Other glycan degradation_Homo sapiens_hsa005111.75265600
3Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.62952932
4Chronic myeloid leukemia_Homo sapiens_hsa052201.62499225
5Colorectal cancer_Homo sapiens_hsa052101.57902224
6Non-small cell lung cancer_Homo sapiens_hsa052231.57454012
7Olfactory transduction_Homo sapiens_hsa047401.53278429
8Glioma_Homo sapiens_hsa052141.51394005
9Long-term potentiation_Homo sapiens_hsa047201.49140391
10Endometrial cancer_Homo sapiens_hsa052131.48607695
11mTOR signaling pathway_Homo sapiens_hsa041501.48224874
12Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.46687528
13Neurotrophin signaling pathway_Homo sapiens_hsa047221.44711959
14Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.42643645
15Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.42012156
16mRNA surveillance pathway_Homo sapiens_hsa030151.41982470
17Notch signaling pathway_Homo sapiens_hsa043301.40798551
18Thyroid hormone signaling pathway_Homo sapiens_hsa049191.36051435
19Oocyte meiosis_Homo sapiens_hsa041141.34732497
20B cell receptor signaling pathway_Homo sapiens_hsa046621.34634611
21Estrogen signaling pathway_Homo sapiens_hsa049151.33951861
22VEGF signaling pathway_Homo sapiens_hsa043701.33430648
23Circadian entrainment_Homo sapiens_hsa047131.31059062
24Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.30735254
25Pentose phosphate pathway_Homo sapiens_hsa000301.29437228
26Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.28040946
27Prion diseases_Homo sapiens_hsa050201.26823998
28Gap junction_Homo sapiens_hsa045401.25856052
29Dopaminergic synapse_Homo sapiens_hsa047281.25082198
30Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.24111213
31Type II diabetes mellitus_Homo sapiens_hsa049301.22950010
32Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.22894475
33Prostate cancer_Homo sapiens_hsa052151.22516681
34Spliceosome_Homo sapiens_hsa030401.21727561
35Central carbon metabolism in cancer_Homo sapiens_hsa052301.19775843
36Aldosterone synthesis and secretion_Homo sapiens_hsa049251.18155372
37Adherens junction_Homo sapiens_hsa045201.16590093
38T cell receptor signaling pathway_Homo sapiens_hsa046601.15815333
39Biosynthesis of amino acids_Homo sapiens_hsa012301.13877557
40Axon guidance_Homo sapiens_hsa043601.12690378
41Gastric acid secretion_Homo sapiens_hsa049711.12138703
42Synaptic vesicle cycle_Homo sapiens_hsa047211.11431391
43Primary immunodeficiency_Homo sapiens_hsa053401.09916652
44Phosphatidylinositol signaling system_Homo sapiens_hsa040701.05202175
45Cholinergic synapse_Homo sapiens_hsa047251.04624406
46Oxytocin signaling pathway_Homo sapiens_hsa049211.04192883
47Fructose and mannose metabolism_Homo sapiens_hsa000511.02198598
48Pancreatic cancer_Homo sapiens_hsa052121.01710431
49Morphine addiction_Homo sapiens_hsa050321.01242976
50Apoptosis_Homo sapiens_hsa042101.00746099
51Carbohydrate digestion and absorption_Homo sapiens_hsa049731.00649414
52Amphetamine addiction_Homo sapiens_hsa050310.98322785
53Alcoholism_Homo sapiens_hsa050340.98274037
54DNA replication_Homo sapiens_hsa030300.97802980
55Glutamatergic synapse_Homo sapiens_hsa047240.97339551
56Dorso-ventral axis formation_Homo sapiens_hsa043200.95976334
57Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.95675548
58Lysine degradation_Homo sapiens_hsa003100.95670626
59Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.94495134
60GABAergic synapse_Homo sapiens_hsa047270.94459239
61MicroRNAs in cancer_Homo sapiens_hsa052060.94380349
62HTLV-I infection_Homo sapiens_hsa051660.94139438
63Inositol phosphate metabolism_Homo sapiens_hsa005620.93978802
64Proteoglycans in cancer_Homo sapiens_hsa052050.93902293
65Hepatitis C_Homo sapiens_hsa051600.93191722
66Cell cycle_Homo sapiens_hsa041100.93100905
67Insulin signaling pathway_Homo sapiens_hsa049100.92545138
68Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.92479204
69Basal cell carcinoma_Homo sapiens_hsa052170.92021300
70Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.91927535
71Insulin secretion_Homo sapiens_hsa049110.91105606
72ErbB signaling pathway_Homo sapiens_hsa040120.90926202
73Focal adhesion_Homo sapiens_hsa045100.89284911
74Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.87227634
75Renin secretion_Homo sapiens_hsa049240.86652796
76GnRH signaling pathway_Homo sapiens_hsa049120.86429306
77Melanogenesis_Homo sapiens_hsa049160.86149644
78Viral carcinogenesis_Homo sapiens_hsa052030.85671972
79Cocaine addiction_Homo sapiens_hsa050300.85601161
80Glucagon signaling pathway_Homo sapiens_hsa049220.85403494
81Phospholipase D signaling pathway_Homo sapiens_hsa040720.85320602
82Viral myocarditis_Homo sapiens_hsa054160.84862802
83Osteoclast differentiation_Homo sapiens_hsa043800.83837441
84Salivary secretion_Homo sapiens_hsa049700.83770237
85Renal cell carcinoma_Homo sapiens_hsa052110.83346887
86Acute myeloid leukemia_Homo sapiens_hsa052210.82448796
87Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.82313073
88Platelet activation_Homo sapiens_hsa046110.80675565
89Sphingolipid signaling pathway_Homo sapiens_hsa040710.80569276
90HIF-1 signaling pathway_Homo sapiens_hsa040660.80479764
91Hippo signaling pathway_Homo sapiens_hsa043900.80409115
92cGMP-PKG signaling pathway_Homo sapiens_hsa040220.79401660
93Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.79229849
94Base excision repair_Homo sapiens_hsa034100.79099368
95Influenza A_Homo sapiens_hsa051640.78750880
96Endocytosis_Homo sapiens_hsa041440.78132683
97RNA transport_Homo sapiens_hsa030130.78038083
98Longevity regulating pathway - mammal_Homo sapiens_hsa042110.77413811
99Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.76436016
100Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.75352974
101Prolactin signaling pathway_Homo sapiens_hsa049170.75183981
102Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.73592580
103Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.73407173
104Toll-like receptor signaling pathway_Homo sapiens_hsa046200.73406155
105Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.72969011
106Insulin resistance_Homo sapiens_hsa049310.72758108
107Amoebiasis_Homo sapiens_hsa051460.72719203
108Herpes simplex infection_Homo sapiens_hsa051680.71792137
109AMPK signaling pathway_Homo sapiens_hsa041520.71688049
110Rap1 signaling pathway_Homo sapiens_hsa040150.70997166
111Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.70503516
112Wnt signaling pathway_Homo sapiens_hsa043100.69862909
113Glycosaminoglycan degradation_Homo sapiens_hsa005310.69406872
114Epstein-Barr virus infection_Homo sapiens_hsa051690.69373382
1152-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.69289506
116Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.68257283
117MAPK signaling pathway_Homo sapiens_hsa040100.67892209
118N-Glycan biosynthesis_Homo sapiens_hsa005100.67820389
119Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.67645252
120AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.67363876
121Hepatitis B_Homo sapiens_hsa051610.66995797
122Measles_Homo sapiens_hsa051620.66974668
123Leukocyte transendothelial migration_Homo sapiens_hsa046700.66456139
124Shigellosis_Homo sapiens_hsa051310.66321971
125Small cell lung cancer_Homo sapiens_hsa052220.66200130
126Thyroid cancer_Homo sapiens_hsa052160.66022774
127Choline metabolism in cancer_Homo sapiens_hsa052310.65834678
128Bladder cancer_Homo sapiens_hsa052190.64660152
129Toxoplasmosis_Homo sapiens_hsa051450.64445845
130cAMP signaling pathway_Homo sapiens_hsa040240.64182247
131Cyanoamino acid metabolism_Homo sapiens_hsa004600.64087062
132Galactose metabolism_Homo sapiens_hsa000520.63989458
133Salmonella infection_Homo sapiens_hsa051320.61607622
134TNF signaling pathway_Homo sapiens_hsa046680.60699810
135Pathways in cancer_Homo sapiens_hsa052000.59886120
136Carbon metabolism_Homo sapiens_hsa012000.59235827
137Adipocytokine signaling pathway_Homo sapiens_hsa049200.58188476
138FoxO signaling pathway_Homo sapiens_hsa040680.56653014
139Regulation of actin cytoskeleton_Homo sapiens_hsa048100.54020411
140Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.51532074

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