CCDC102A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1deoxyribonucleoside monophosphate metabolic process (GO:0009162)6.11206147
2negative regulation of mRNA splicing, via spliceosome (GO:0048025)5.61962575
3protein heterotrimerization (GO:0070208)5.54944436
4collagen fibril organization (GO:0030199)4.72817770
5mucosal-associated lymphoid tissue development (GO:0048537)4.70173557
6Peyers patch development (GO:0048541)4.70173557
7chondrocyte proliferation (GO:0035988)4.57529125
8negative regulation of mRNA processing (GO:0050686)4.55112833
9bone trabecula formation (GO:0060346)4.43068890
10negative regulation of RNA splicing (GO:0033119)4.37112829
11negative regulation of erythrocyte differentiation (GO:0045647)4.28971967
12endodermal cell differentiation (GO:0035987)4.25255622
13pyrimidine deoxyribonucleotide catabolic process (GO:0009223)4.13907961
14basement membrane organization (GO:0071711)4.12214394
15UTP biosynthetic process (GO:0006228)4.06057565
16nucleobase-containing small molecule interconversion (GO:0015949)4.05943060
17pyrimidine deoxyribonucleotide metabolic process (GO:0009219)4.04922630
18regulation of mitochondrial translation (GO:0070129)4.03850413
19pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.99451452
20negative regulation of mRNA metabolic process (GO:1903312)3.97336945
21DNA synthesis involved in DNA repair (GO:0000731)3.94205659
22negative regulation of JAK-STAT cascade (GO:0046426)3.90163326
23GTP biosynthetic process (GO:0006183)3.89750884
24sequestering of extracellular ligand from receptor (GO:0035581)3.88144797
25pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.88144227
26DNA strand elongation involved in DNA replication (GO:0006271)3.84991672
27mature B cell differentiation involved in immune response (GO:0002313)3.83439351
28positive regulation of endothelial cell apoptotic process (GO:2000353)3.81920603
29UTP metabolic process (GO:0046051)3.81221802
30DNA strand elongation (GO:0022616)3.77350233
31telomere maintenance via semi-conservative replication (GO:0032201)3.67584437
32wound healing, spreading of epidermal cells (GO:0035313)3.65961787
33pyrimidine nucleotide catabolic process (GO:0006244)3.61863720
34vascular endothelial growth factor signaling pathway (GO:0038084)3.60210151
35guanosine-containing compound biosynthetic process (GO:1901070)3.53037063
36cell migration involved in heart development (GO:0060973)3.52039170
37pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.49061182
38deoxyribose phosphate biosynthetic process (GO:0046385)3.49024526
392-deoxyribonucleotide biosynthetic process (GO:0009265)3.49024526
40deoxyribonucleotide catabolic process (GO:0009264)3.43617467
41translesion synthesis (GO:0019985)3.41467111
42purine deoxyribonucleotide catabolic process (GO:0009155)3.36045794
43paraxial mesoderm development (GO:0048339)3.36037773
44dermatan sulfate biosynthetic process (GO:0030208)3.34944181
45CTP metabolic process (GO:0046036)3.34197855
46CTP biosynthetic process (GO:0006241)3.34197855
47pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)3.33760956
48positive regulation of epithelial to mesenchymal transition (GO:0010718)3.31236702
49polarized epithelial cell differentiation (GO:0030859)3.30959571
50deoxyribose phosphate catabolic process (GO:0046386)3.30085191
51viral transcription (GO:0019083)3.30064517
52centrosome duplication (GO:0051298)3.26011077
53folic acid metabolic process (GO:0046655)3.25706344
54epithelial cell-cell adhesion (GO:0090136)3.25644839
55cell adhesion mediated by integrin (GO:0033627)3.23870614
56definitive hemopoiesis (GO:0060216)3.21505731
57UV protection (GO:0009650)3.20569812
58translational termination (GO:0006415)3.20247373
59pinocytosis (GO:0006907)3.19782568
60regulation of mammary gland epithelial cell proliferation (GO:0033599)3.18330256
61regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.17483799
623-UTR-mediated mRNA stabilization (GO:0070935)3.16812822
63positive regulation of blood vessel endothelial cell migration (GO:0043536)3.14461360
64base-excision repair (GO:0006284)3.09833720
65cellular response to vascular endothelial growth factor stimulus (GO:0035924)3.07216833
66grooming behavior (GO:0007625)3.07019397
67neuron projection extension involved in neuron projection guidance (GO:1902284)3.06252789
68axon extension involved in axon guidance (GO:0048846)3.06252789
69negative regulation of B cell apoptotic process (GO:0002903)3.06151208
70dermatan sulfate metabolic process (GO:0030205)3.06048454
71regulation of SMAD protein import into nucleus (GO:0060390)3.05727090
72skin morphogenesis (GO:0043589)3.04027776
73protein maturation by protein folding (GO:0022417)3.02663725
74post-embryonic morphogenesis (GO:0009886)3.00255410
75regulation of protein heterodimerization activity (GO:0043497)2.99713364
76regulation of tight junction assembly (GO:2000810)2.99499754
77peptidyl-arginine omega-N-methylation (GO:0035247)2.99389126
78collagen metabolic process (GO:0032963)2.99167121
79base-excision repair, AP site formation (GO:0006285)2.98708131
80wound healing, spreading of cells (GO:0044319)2.98576910
81hippo signaling (GO:0035329)2.98491391
82proline biosynthetic process (GO:0006561)2.98106745
83craniofacial suture morphogenesis (GO:0097094)2.97023893
84negative regulation of fatty acid transport (GO:2000192)2.95078625
85maturation of SSU-rRNA (GO:0030490)2.95032505
86planar cell polarity pathway involved in neural tube closure (GO:0090179)2.93824205
87protein retention in ER lumen (GO:0006621)2.92475735
88focal adhesion assembly (GO:0048041)2.92281920
89cell-substrate adherens junction assembly (GO:0007045)2.92281920
90rRNA transcription (GO:0009303)2.92129081
91endocardial cushion development (GO:0003197)2.91736337
92outer ear morphogenesis (GO:0042473)2.91464480
93telomere maintenance via recombination (GO:0000722)2.89772105
94endothelial tube morphogenesis (GO:0061154)2.89682416
95morphogenesis of an endothelium (GO:0003159)2.89682416
96fibril organization (GO:0097435)2.87921224
97gland morphogenesis (GO:0022612)2.85899501
982-deoxyribonucleotide metabolic process (GO:0009394)2.85832930
99pyrimidine nucleoside monophosphate metabolic process (GO:0009129)2.85830217
100collagen catabolic process (GO:0030574)2.85683390
101translational elongation (GO:0006414)2.85199102
102folic acid-containing compound biosynthetic process (GO:0009396)2.83007911
103retina vasculature morphogenesis in camera-type eye (GO:0061299)2.82825835
104regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.82577139
105regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.81674300
106mitotic recombination (GO:0006312)2.79804643
107negative regulation of cell aging (GO:0090344)2.79771687
108cranial suture morphogenesis (GO:0060363)2.78948483
109negative regulation of chondrocyte differentiation (GO:0032331)2.78429320
110DNA unwinding involved in DNA replication (GO:0006268)2.76366632
111pyrimidine nucleotide biosynthetic process (GO:0006221)2.73426303
112plasma membrane repair (GO:0001778)2.73149136
113multicellular organismal macromolecule metabolic process (GO:0044259)2.72205377
114mitotic chromosome condensation (GO:0007076)2.71912338
115ribosomal small subunit assembly (GO:0000028)2.71555446
116maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.70349953
117lymph vessel development (GO:0001945)2.69305372
118heterochromatin organization (GO:0070828)2.69002707
119ribosomal small subunit biogenesis (GO:0042274)2.68038265
120blood vessel maturation (GO:0001955)2.68014144
121positive regulation of SMAD protein import into nucleus (GO:0060391)2.65482807
122deoxyribose phosphate metabolic process (GO:0019692)2.65325735
123metanephric mesenchyme development (GO:0072075)2.63536838
124establishment of apical/basal cell polarity (GO:0035089)2.63475753
125pyrimidine nucleotide metabolic process (GO:0006220)2.63087456
126mature B cell differentiation (GO:0002335)2.62354515
127G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.61837419
128regulation of heart morphogenesis (GO:2000826)2.61457487
129regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307)2.61214582
130embryonic cranial skeleton morphogenesis (GO:0048701)2.60723736
131nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.60325604
132translational initiation (GO:0006413)2.59038193
133establishment of integrated proviral latency (GO:0075713)2.58023620
134pyrimidine nucleoside biosynthetic process (GO:0046134)2.57026347
135mesenchymal-epithelial cell signaling (GO:0060638)2.56129551
136multicellular organismal catabolic process (GO:0044243)2.56046482
137peptidyl-proline hydroxylation (GO:0019511)2.55314366
138SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.55065422
139negative regulation of smooth muscle cell migration (GO:0014912)2.54601272
140extracellular matrix disassembly (GO:0022617)2.53712944
141substrate adhesion-dependent cell spreading (GO:0034446)2.52990581
142extracellular fibril organization (GO:0043206)2.52978600
143endothelial cell proliferation (GO:0001935)2.52524772
144multicellular organismal metabolic process (GO:0044236)2.51862868
145adherens junction assembly (GO:0034333)2.51799774
146cell proliferation involved in metanephros development (GO:0072203)2.51512463
147viral life cycle (GO:0019058)2.51030961
148kidney mesenchyme development (GO:0072074)2.50839596
149mammary gland epithelial cell differentiation (GO:0060644)2.50268805
150DNA biosynthetic process (GO:0071897)2.49526676
151anatomical structure regression (GO:0060033)2.48832091
152protein localization to cell surface (GO:0034394)2.48039664
153protein targeting to ER (GO:0045047)2.47500109
154deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.46650687
155regulation of response to osmotic stress (GO:0047484)2.46444944
156mRNA stabilization (GO:0048255)2.46413457
157RNA stabilization (GO:0043489)2.46413457
158nucleotide-excision repair, DNA gap filling (GO:0006297)2.46065670
159cellular protein complex disassembly (GO:0043624)2.45353775
160apoptotic cell clearance (GO:0043277)2.44925578
161granulocyte differentiation (GO:0030851)2.44761300
162trabecula formation (GO:0060343)2.44586942
163formation of translation preinitiation complex (GO:0001731)2.44197095
164deoxyribonucleotide biosynthetic process (GO:0009263)2.44053643
165cotranslational protein targeting to membrane (GO:0006613)2.43183593
166maternal placenta development (GO:0001893)2.42991640
167histone arginine methylation (GO:0034969)2.42844072
168cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.42446857
169negative regulation of cartilage development (GO:0061037)2.42369480
170apoptotic process involved in morphogenesis (GO:0060561)2.41689731
171vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.41160139
172negative regulation of DNA repair (GO:0045738)2.41107925
173negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948)2.40191456
174protein hydroxylation (GO:0018126)2.39102449
175cell migration involved in sprouting angiogenesis (GO:0002042)2.37369560
176negative regulation of embryonic development (GO:0045992)2.33678827
177establishment of protein localization to endoplasmic reticulum (GO:0072599)2.33283719
178negative regulation of catenin import into nucleus (GO:0035414)2.32175328
179regulation of mitotic spindle organization (GO:0060236)2.30963433
180regulation of transcription from RNA polymerase II promoter involved in heart development (GO:1901212.29054457

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.01320197
2RARG_19884340_ChIP-ChIP_MEFs_Mouse3.53987286
3EGR1_19374776_ChIP-ChIP_THP-1_Human3.53330032
4TP63_17297297_ChIP-ChIP_HaCaT_Human3.51966762
5EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.15494679
6TRIM28_21343339_ChIP-Seq_HEK293_Human3.06370594
7MYC_18555785_ChIP-Seq_MESCs_Mouse2.94948647
8NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.84942793
9FOXM1_23109430_ChIP-Seq_U2OS_Human2.75960419
10* ELK3_25401928_ChIP-Seq_HUVEC_Human2.37236230
11* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse2.34544956
12* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.27504427
13CLOCK_20551151_ChIP-Seq_293T_Human2.20477116
14HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.15083319
15TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.13392407
16MYC_22102868_ChIP-Seq_BL_Human1.95666686
17RBPJ_22232070_ChIP-Seq_NCS_Mouse1.94587428
18TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.93526066
19TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.92608509
20PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.86507299
21TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.76449294
22NELFA_20434984_ChIP-Seq_ESCs_Mouse1.75870128
23NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.74635503
24FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.73695199
25THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.72035189
26POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.71422283
27ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.71215633
28HIF1A_21447827_ChIP-Seq_MCF-7_Human1.71215236
29VDR_21846776_ChIP-Seq_THP-1_Human1.70163623
30XRN2_22483619_ChIP-Seq_HELA_Human1.68882341
31TET1_21451524_ChIP-Seq_MESCs_Mouse1.67848831
32MYC_19030024_ChIP-ChIP_MESCs_Mouse1.65174778
33AR_21909140_ChIP-Seq_LNCAP_Human1.63148363
34MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.61806854
35MYC_18358816_ChIP-ChIP_MESCs_Mouse1.60040102
36STAT3_1855785_ChIP-Seq_MESCs_Mouse1.58391693
37P68_20966046_ChIP-Seq_HELA_Human1.55674464
38TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.53426763
39KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.51230607
40VDR_24763502_ChIP-Seq_THP-1_Human1.50587171
41E2F4_17652178_ChIP-ChIP_JURKAT_Human1.50369308
42ATF3_27146783_Chip-Seq_COLON_Human1.48154721
43CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.48123429
44SA1_27219007_Chip-Seq_ERYTHROID_Human1.46414612
45TP53_22127205_ChIP-Seq_IMR90_Human1.45355976
46HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.43241698
47MAF_26560356_Chip-Seq_TH2_Human1.42410704
48JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.42167850
49TCF3_18692474_ChIP-Seq_MEFs_Mouse1.42119344
50BP1_19119308_ChIP-ChIP_Hs578T_Human1.42039396
51KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.40008337
52CIITA_25753668_ChIP-Seq_RAJI_Human1.38934082
53ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.38739555
54BRD4_25478319_ChIP-Seq_HGPS_Human1.38040062
55CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.37417898
56WT1_19549856_ChIP-ChIP_CCG9911_Human1.37092712
57NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.36221704
58KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.35180353
59KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.34809732
60KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.34809732
61KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.34809732
62ELF1_20517297_ChIP-Seq_JURKAT_Human1.34749581
63KDM2B_26808549_Chip-Seq_SUP-B15_Human1.33456828
64CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.32359768
65NOTCH1_21737748_ChIP-Seq_TLL_Human1.32151931
66EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.31796675
67TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.29400058
68ZFX_18555785_ChIP-Seq_MESCs_Mouse1.29193308
69E2F1_18555785_ChIP-Seq_MESCs_Mouse1.28943621
70ZNF263_19887448_ChIP-Seq_K562_Human1.28236721
71* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.28180253
72TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.28068232
73ELF1_17652178_ChIP-ChIP_JURKAT_Human1.27504480
74CTCF_27219007_Chip-Seq_ERYTHROID_Human1.26062829
75KDM2B_26808549_Chip-Seq_JURKAT_Human1.25409995
76* SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.24306331
77RACK7_27058665_Chip-Seq_MCF-7_Human1.24108651
78ERG_20887958_ChIP-Seq_HPC-7_Mouse1.21626870
79KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.21606160
80NANOG_18555785_ChIP-Seq_MESCs_Mouse1.21098186
81PU.1_20513432_ChIP-Seq_Bcells_Mouse1.20620857
82POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.20286857
83* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.18905543
84* KDM2B_26808549_Chip-Seq_DND41_Human1.18843751
85SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.18842394
86ESR1_15608294_ChIP-ChIP_MCF-7_Human1.18645770
87DCP1A_22483619_ChIP-Seq_HELA_Human1.18080496
88* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.18071792
89KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.17916950
90DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.17794579
91SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.17595447
92BCL6_27268052_Chip-Seq_Bcells_Human1.17257318
93* MAF_26560356_Chip-Seq_TH1_Human1.17150053
94PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.16561072
95GABP_19822575_ChIP-Seq_HepG2_Human1.16457307
96SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.16047304
97CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.15888727
98THAP11_20581084_ChIP-Seq_MESCs_Mouse1.15679445
99UTX_26944678_Chip-Seq_JUKART_Human1.15636547
100P300_27058665_Chip-Seq_ZR-75-30cells_Human1.15585217
101UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.15463848
102CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.14879232
103STAT6_21828071_ChIP-Seq_BEAS2B_Human1.14261228
104CTCF_21964334_Chip-Seq_Bcells_Human1.14107062
105SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.13771295
106SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.13771295
107E2F1_21310950_ChIP-Seq_MCF-7_Human1.12894454
108ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.12729933
109CTCF_18555785_ChIP-Seq_MESCs_Mouse1.12693132
110BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.12375393
111BRD4_27068464_Chip-Seq_AML-cells_Mouse1.12081834
112ETS1_20019798_ChIP-Seq_JURKAT_Human1.11447902
113RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.11375282
114E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.11303614
115CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.11069011
116HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.10888060
117TFEB_21752829_ChIP-Seq_HELA_Human1.10155029
118LXR_22292898_ChIP-Seq_THP-1_Human1.10127174
119SCL_19346495_ChIP-Seq_HPC-7_Human1.09869799
120ELK1_22589737_ChIP-Seq_MCF10A_Human1.09758439
121SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.09682437
122KDM2B_26808549_Chip-Seq_K562_Human1.09539320
123STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.09515901
124MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.09426712
125CTCF_26484167_Chip-Seq_Bcells_Mouse1.09398771
126KLF4_18555785_ChIP-Seq_MESCs_Mouse1.09397560
127TCF7_22412390_ChIP-Seq_EML_Mouse1.09362674
128ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.08960418
129CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.08484353
130SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.07957616
131UBF1/2_26484160_Chip-Seq_HMECs_Human1.07130367
132FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.06750058
133YY1_21170310_ChIP-Seq_MESCs_Mouse1.06661185
134TTF2_22483619_ChIP-Seq_HELA_Human1.06293120
135KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.05498025
136CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.04539642
137GATA1_22383799_ChIP-Seq_G1ME_Mouse1.04365782
138PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.04269680
139NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.03807286
140SMC1_22415368_ChIP-Seq_MEFs_Mouse1.03558807
141CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.03357856
142CREB1_26743006_Chip-Seq_LNCaP_Human1.03337264
143RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.03311527
144SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.03069447
145* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.02977760
146NCOR1_26117541_ChIP-Seq_K562_Human1.02805724

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen6.62589125
2MP0005503_abnormal_tendon_morphology4.09966482
3MP0003705_abnormal_hypodermis_morpholog4.00052774
4MP0005275_abnormal_skin_tensile3.84420486
5MP0003279_aneurysm3.54348298
6MP0005623_abnormal_meninges_morphology2.88950556
7MP0004272_abnormal_basement_membrane2.73443905
8MP0001958_emphysema2.65485673
9MP0004510_myositis2.50781239
10MP0010030_abnormal_orbit_morphology2.41327828
11MP0010352_gastrointestinal_tract_polyps2.35629779
12MP0005397_hematopoietic_system_phenotyp2.35524428
13MP0001545_abnormal_hematopoietic_system2.35524428
14MP0006054_spinal_hemorrhage2.31748664
15MP0003111_abnormal_nucleus_morphology2.18444273
16MP0002234_abnormal_pharynx_morphology2.18274438
17MP0005023_abnormal_wound_healing2.00110684
18MP0003566_abnormal_cell_adhesion1.99706259
19MP0009384_cardiac_valve_regurgitation1.97391658
20MP0010368_abnormal_lymphatic_system1.83404898
21MP0000490_abnormal_crypts_of1.82143177
22MP0004858_abnormal_nervous_system1.81122185
23MP0000733_abnormal_muscle_development1.79145941
24MP0005508_abnormal_skeleton_morphology1.76341749
25MP0003763_abnormal_thymus_physiology1.72864858
26MP0003385_abnormal_body_wall1.70638542
27MP0000678_abnormal_parathyroid_gland1.68089750
28MP0004185_abnormal_adipocyte_glucose1.67487695
29MP0001849_ear_inflammation1.66128740
30MP0005257_abnormal_intraocular_pressure1.59638311
31MP0005330_cardiomyopathy1.57564346
32MP0009379_abnormal_foot_pigmentation1.51456180
33MP0002060_abnormal_skin_morphology1.50996080
34MP0003693_abnormal_embryo_hatching1.50664028
35MP0001243_abnormal_dermal_layer1.49449966
36MP0000767_abnormal_smooth_muscle1.49289335
37MP0003091_abnormal_cell_migration1.49184779
38MP0009333_abnormal_splenocyte_physiolog1.46715185
39MP0008057_abnormal_DNA_replication1.45988521
40MP0010094_abnormal_chromosome_stability1.44081339
41MP0001879_abnormal_lymphatic_vessel1.43243608
42MP0004808_abnormal_hematopoietic_stem1.39375824
43MP0000465_gastrointestinal_hemorrhage1.38748240
44MP0009053_abnormal_anal_canal1.36463759
45MP0009250_abnormal_appendicular_skeleto1.31709433
46MP0005076_abnormal_cell_differentiation1.30612999
47MP0002877_abnormal_melanocyte_morpholog1.28574120
48MP0000750_abnormal_muscle_regeneration1.27677962
49MP0002396_abnormal_hematopoietic_system1.26174930
50MP0002019_abnormal_tumor_incidence1.26024075
51MP0002932_abnormal_joint_morphology1.24631264
52MP0003941_abnormal_skin_development1.24024959
53MP0000703_abnormal_thymus_morphology1.23065139
54MP0005501_abnormal_skin_physiology1.22649470
55MP0005451_abnormal_body_composition1.21830596
56MP0003453_abnormal_keratinocyte_physiol1.20957332
57MP0000613_abnormal_salivary_gland1.19840680
58MP0001348_abnormal_lacrimal_gland1.19363624
59MP0001873_stomach_inflammation1.18579770
60MP0005375_adipose_tissue_phenotype1.18103663
61MP0002295_abnormal_pulmonary_circulatio1.17458333
62MP0008007_abnormal_cellular_replicative1.17016105
63MP0003942_abnormal_urinary_system1.13371014
64MP0008058_abnormal_DNA_repair1.12158203
65MP0003436_decreased_susceptibility_to1.11670326
66MP0003115_abnormal_respiratory_system1.11369633
67MP0005621_abnormal_cell_physiology1.11013287
68MP0000428_abnormal_craniofacial_morphol1.10468371
69MP0002933_joint_inflammation1.09762773
70MP0002282_abnormal_trachea_morphology1.08829766
71MP0002108_abnormal_muscle_morphology1.08268264
72MP0002398_abnormal_bone_marrow1.05087238
73MP0004197_abnormal_fetal_growth/weight/1.04281241
74MP0002132_abnormal_respiratory_system1.03151462
75MP0002925_abnormal_cardiovascular_devel1.02858824
76MP0001881_abnormal_mammary_gland1.02680711
77MP0000534_abnormal_ureter_morphology1.00294220
78MP0002128_abnormal_blood_circulation1.00228889
79MP0002249_abnormal_larynx_morphology1.00200219
80MP0001614_abnormal_blood_vessel0.99537069
81MP0002722_abnormal_immune_system0.99062502
82MP0005390_skeleton_phenotype0.98681903
83MP0000049_abnormal_middle_ear0.98323570
84MP0000858_altered_metastatic_potential0.97894404
85MP0001915_intracranial_hemorrhage0.96768057
86MP0002089_abnormal_postnatal_growth/wei0.95604989
87MP0010630_abnormal_cardiac_muscle0.95098268
88MP0004084_abnormal_cardiac_muscle0.94914549
89MP0000313_abnormal_cell_death0.93761658
90MP0002113_abnormal_skeleton_development0.92155970
91MP0001661_extended_life_span0.90634456
92MP0001542_abnormal_bone_strength0.90616399
93MP0003283_abnormal_digestive_organ0.90138775
94MP0003567_abnormal_fetal_cardiomyocyte0.89654465
95MP0000163_abnormal_cartilage_morphology0.89647455
96MP0001730_embryonic_growth_arrest0.87952543
97MP0002111_abnormal_tail_morphology0.87828281
98MP0002896_abnormal_bone_mineralization0.87580985
99MP0003077_abnormal_cell_cycle0.87419776
100MP0004233_abnormal_muscle_weight0.86861343
101MP0004957_abnormal_blastocyst_morpholog0.86121919
102MP0000350_abnormal_cell_proliferation0.85890881
103MP0003984_embryonic_growth_retardation0.85691983
104MP0002088_abnormal_embryonic_growth/wei0.85355112
105MP0003448_altered_tumor_morphology0.85222171
106MP0001175_abnormal_lung_morphology0.85024825
107MP0002085_abnormal_embryonic_tissue0.84744613
108MP0008932_abnormal_embryonic_tissue0.84489305
109MP0003935_abnormal_craniofacial_develop0.84220979
110MP0006138_congestive_heart_failure0.84126668
111MP0002086_abnormal_extraembryonic_tissu0.84046796
112MP0003806_abnormal_nucleotide_metabolis0.83838769
113MP0000537_abnormal_urethra_morphology0.83634922
114MP0001697_abnormal_embryo_size0.83328211
115MP0001672_abnormal_embryogenesis/_devel0.83309512
116MP0005380_embryogenesis_phenotype0.83309512
117MP0000762_abnormal_tongue_morphology0.81766986
118MP0010307_abnormal_tumor_latency0.81638460
119MP0003123_paternal_imprinting0.81363667
120MP0000751_myopathy0.80502562
121MP0002115_abnormal_skeleton_extremities0.80434234
122MP0002429_abnormal_blood_cell0.79151002
123MP0005666_abnormal_adipose_tissue0.78739060
124MP0002084_abnormal_developmental_patter0.78395095
125MP0000759_abnormal_skeletal_muscle0.77766940
126MP0005464_abnormal_platelet_physiology0.77755662
127MP0003937_abnormal_limbs/digits/tail_de0.77653121
128MP0001299_abnormal_eye_distance/0.77358956
129MP0003755_abnormal_palate_morphology0.77149143
130MP0000266_abnormal_heart_morphology0.76237143
131MP0000689_abnormal_spleen_morphology0.75922891
132MP0004087_abnormal_muscle_fiber0.75636699
133MP0009278_abnormal_bone_marrow0.74664420
134MP0000566_synostosis0.74581287
135MP0000003_abnormal_adipose_tissue0.73097158
136MP0002080_prenatal_lethality0.72936657
137MP0000013_abnormal_adipose_tissue0.72889345
138MP0000432_abnormal_head_morphology0.71572492
139MP0005084_abnormal_gallbladder_morpholo0.71414542
140MP0000749_muscle_degeneration0.68852473
141MP0000516_abnormal_urinary_system0.68589311
142MP0005367_renal/urinary_system_phenotyp0.68589311
143MP0003300_gastrointestinal_ulcer0.68560099

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)8.45771916
2Premature rupture of membranes (HP:0001788)6.87777489
3Shallow orbits (HP:0000586)4.95612634
4Ankle contracture (HP:0006466)4.87258516
5Aortic dissection (HP:0002647)4.54090624
6Peritonitis (HP:0002586)4.21164905
7Broad metatarsal (HP:0001783)4.18949740
8Cerebral aneurysm (HP:0004944)4.14123560
9Soft skin (HP:0000977)4.01584881
10Aortic aneurysm (HP:0004942)3.91005718
11Cervical subluxation (HP:0003308)3.80122936
12Achilles tendon contracture (HP:0001771)3.78993329
13Dilatation of the ascending aorta (HP:0005111)3.78748194
14Vertebral compression fractures (HP:0002953)3.76058008
15Atrophic scars (HP:0001075)3.62778884
16Bladder diverticulum (HP:0000015)3.60955370
17Abnormality of dentin (HP:0010299)3.53841370
18Wrist flexion contracture (HP:0001239)3.48573894
19Rectal prolapse (HP:0002035)3.47488799
20Biconcave vertebral bodies (HP:0004586)3.41092946
21Fragile skin (HP:0001030)3.32519885
22Genu recurvatum (HP:0002816)3.28065515
23Abnormality of the Achilles tendon (HP:0005109)3.21833139
24Increased connective tissue (HP:0009025)3.17847938
25Type 1 muscle fiber predominance (HP:0003803)3.17556979
26Spinal rigidity (HP:0003306)3.12923640
27Blue sclerae (HP:0000592)3.08182418
28Neonatal short-limb short stature (HP:0008921)3.05746528
29Centrally nucleated skeletal muscle fibers (HP:0003687)3.03103601
30Mitral valve prolapse (HP:0001634)3.02833786
31Broad distal phalanx of finger (HP:0009836)2.99792041
32Hyperacusis (HP:0010780)2.96358179
33Wormian bones (HP:0002645)2.91600757
34Bowel diverticulosis (HP:0005222)2.90207241
35Short 4th metacarpal (HP:0010044)2.87252815
36Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.87252815
37Cellulitis (HP:0100658)2.84668083
38Progressive muscle weakness (HP:0003323)2.77635524
39Premature skin wrinkling (HP:0100678)2.73632809
40Increased density of long bones (HP:0006392)2.71916538
41Follicular hyperkeratosis (HP:0007502)2.53532387
42Patent foramen ovale (HP:0001655)2.52962017
43Nonimmune hydrops fetalis (HP:0001790)2.51555526
44Thin bony cortex (HP:0002753)2.51059295
45Abnormality of the acetabulum (HP:0003170)2.50784872
46Abnormality of the peritoneum (HP:0002585)2.49376795
47Selective tooth agenesis (HP:0001592)2.47296500
48Ragged-red muscle fibers (HP:0003200)2.46155133
49Round ear (HP:0100830)2.45971566
50Camptodactyly of toe (HP:0001836)2.42438215
51Aneurysm (HP:0002617)2.42354094
52Abnormal delivery (HP:0001787)2.36107025
53Elbow flexion contracture (HP:0002987)2.35764625
54Pseudobulbar signs (HP:0002200)2.35366375
55Slender build (HP:0001533)2.29195840
56Abnormality of the phalanges of the hallux (HP:0010057)2.27388874
57Abnormality of the 4th metacarpal (HP:0010012)2.26975429
58Hyperextensible skin (HP:0000974)2.26839986
59Aortic regurgitation (HP:0001659)2.26042040
60Mesomelia (HP:0003027)2.25740716
61Syringomyelia (HP:0003396)2.24309786
62Spinal cord lesions (HP:0100561)2.24309786
63Breech presentation (HP:0001623)2.20570520
64Abnormality of the calcaneus (HP:0008364)2.19956596
65Microretrognathia (HP:0000308)2.19378234
66Abnormality of the umbilical cord (HP:0010881)2.18836368
67Deviation of the hallux (HP:0010051)2.16021856
68Vascular tortuosity (HP:0004948)2.14042970
69Mildly elevated creatine phosphokinase (HP:0008180)2.13386655
70Redundant skin (HP:0001582)2.12263819
71Mitral regurgitation (HP:0001653)2.08474953
72Hallux valgus (HP:0001822)2.08244058
73Microvesicular hepatic steatosis (HP:0001414)2.05937098
74Atelectasis (HP:0100750)2.05881120
75Bell-shaped thorax (HP:0001591)2.05261871
76Increased variability in muscle fiber diameter (HP:0003557)2.04473880
77Hypoplasia of the capital femoral epiphysis (HP:0003090)2.03486374
78Overgrowth (HP:0001548)2.03469922
79Broad face (HP:0000283)2.03209053
80Slender long bone (HP:0003100)2.03002375
81Eczematoid dermatitis (HP:0000976)2.02503569
82Wide anterior fontanel (HP:0000260)2.00680801
83Joint laxity (HP:0001388)2.00210253
84Flexion contracture of toe (HP:0005830)2.00070547
85Joint contractures involving the joints of the feet (HP:0100492)2.00070547
86Trismus (HP:0000211)1.97953099
87Distal upper limb amyotrophy (HP:0007149)1.96141964
88Upper limb amyotrophy (HP:0009129)1.96141964
89Abnormality of skeletal muscle fiber size (HP:0012084)1.96076070
90Renal duplication (HP:0000075)1.96045219
91Pulmonary artery stenosis (HP:0004415)1.94327484
92Radial bowing (HP:0002986)1.92483230
93Hypertensive crisis (HP:0100735)1.91903959
94Ectopia lentis (HP:0001083)1.91634171
95Hypertriglyceridemia (HP:0002155)1.91403430
96Agammaglobulinemia (HP:0004432)1.90767901
97Abnormality of the tricuspid valve (HP:0001702)1.90085561
98Difficulty climbing stairs (HP:0003551)1.89472177
99Abnormality of the fetal cardiovascular system (HP:0010948)1.89297619
100Abnormal umbilical cord blood vessels (HP:0011403)1.89297619
101Single umbilical artery (HP:0001195)1.89297619
102Knee flexion contracture (HP:0006380)1.89161476
103Partial duplication of the phalanx of hand (HP:0009999)1.87201647
104Abnormality of the thoracic spine (HP:0100711)1.86912630
105Ulnar bowing (HP:0003031)1.86448082
106Arterial tortuosity (HP:0005116)1.85390015
107Generalized amyotrophy (HP:0003700)1.80236338
108Calcaneovalgus deformity (HP:0001848)1.80130590
109Scapular winging (HP:0003691)1.80041102
110Patellar dislocation (HP:0002999)1.79299534
111Dysphonia (HP:0001618)1.79166796
112High pitched voice (HP:0001620)1.76364102
113Coxa vara (HP:0002812)1.75897757
114Thrombocytosis (HP:0001894)1.75708670
115Osteopenia (HP:0000938)1.75539953
116Hydroureter (HP:0000072)1.74431943
117Striae distensae (HP:0001065)1.74254102
118Absent epiphyses (HP:0010577)1.73191923
119Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.73191923
120Bowed forearm bones (HP:0003956)1.73125228
121Bowing of the arm (HP:0006488)1.73125228
122Abnormality of cells of the erythroid lineage (HP:0012130)1.73020642
123Fatigue (HP:0012378)1.72769282
124Cupped ribs (HP:0000887)1.72750274
125Delayed cranial suture closure (HP:0000270)1.72289796
126Broad long bones (HP:0005622)1.71822795
127Reticulocytopenia (HP:0001896)1.71476480
128Hip contracture (HP:0003273)1.70914123
129Testicular atrophy (HP:0000029)1.70868175
130Decreased skull ossification (HP:0004331)1.70267277
131Infantile muscular hypotonia (HP:0008947)1.70097177
132Osteolytic defects of the hand bones (HP:0009699)1.69784678
133Osteolytic defects of the phalanges of the hand (HP:0009771)1.69784678
134Aortic valve stenosis (HP:0001650)1.69599779
135Emphysema (HP:0002097)1.69466574
136Severe visual impairment (HP:0001141)1.67138049
137Bicuspid aortic valve (HP:0001647)1.66723341
138Buphthalmos (HP:0000557)1.66281785
139Inguinal hernia (HP:0000023)1.66119081
140Long palpebral fissure (HP:0000637)1.65682264
141Hand muscle atrophy (HP:0009130)1.65403603
142Hypercortisolism (HP:0001578)1.64911408
143Venous abnormality (HP:0002624)1.64304431
144Partial duplication of thumb phalanx (HP:0009944)1.63977113
145Joint stiffness (HP:0001387)1.63854133
146Broad hallux (HP:0010055)1.63786864
147Thoracic kyphosis (HP:0002942)1.63394641
148Venous insufficiency (HP:0005293)1.62144142
149Short nail (HP:0001799)1.61940847
150Deformed tarsal bones (HP:0008119)1.60536708
151Abnormality of the anterior chamber (HP:0000593)1.59863563

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB33.66803469
2TTN3.60047325
3PKN23.34638184
4SMG13.22022586
5PRPF4B2.81297713
6DDR22.78257356
7LATS22.75546558
8KDR2.50709843
9PDGFRA2.47993709
10TGFBR12.24049421
11TESK22.18540433
12MAP3K102.05070458
13TGFBR22.01568119
14NME21.96886578
15VRK21.95941506
16MAP4K11.92314008
17FLT31.87821330
18BCKDK1.87163598
19EEF2K1.83570278
20RPS6KA41.83082893
21TESK11.82827185
22PAK41.81912141
23LRRK21.80912119
24PAK21.75487190
25ERN11.68869643
26WEE11.68802304
27RIPK11.68727977
28IRAK31.59325611
29EPHA21.55875303
30LATS11.50762716
31MAP2K31.43298450
32ABL21.42963062
33TIE11.42463587
34ILK1.42160128
35STK101.34466737
36MYLK1.31806790
37EPHB21.31294405
38BUB11.30950876
39CDK81.29980832
40SIK11.28736749
41PTK61.26893928
42LIMK11.23391235
43ARAF1.20907980
44SCYL21.18838334
45ICK1.17765850
46PTK21.17534830
47TRPM71.16109239
48RPS6KB21.14022212
49KIT1.10731743
50RPS6KL11.10467436
51RPS6KC11.10467436
52MAP3K111.07583828
53MOS1.06980440
54DMPK1.05724599
55MUSK1.04431999
56BMX1.03251768
57MAP3K81.02830835
58TLK11.00922048
59NEK21.00742795
60MAPK110.99116307
61BRSK20.94446659
62PIM20.93839416
63CDK70.92634420
64MAPKAPK30.92154954
65MTOR0.91434362
66FGFR10.91022555
67MAP3K30.90164478
68PTK2B0.89116640
69RPS6KA60.87605643
70PAK10.85356837
71CDC70.84607545
72CDK120.84136607
73FER0.83324019
74DAPK30.82519223
75STK38L0.79693050
76ZAP700.74807636
77NEK90.74133200
78IRAK40.73768980
79PDGFRB0.72205023
80JAK30.71980136
81DYRK30.71829534
82IRAK20.70374167
83STK30.68333870
84MAP3K130.67729126
85CDK60.67693337
86MAP2K20.66659956
87ROCK10.63897443
88MKNK10.62204998
89EPHA30.61024095
90AURKB0.59959091
91STK40.59873680
92TAF10.59834311
93GRK60.58202089
94PIK3CA0.56531058
95CDK40.56090038
96NEK10.55825112
97PASK0.54613581
98ACVR1B0.54344269
99FGFR40.54282159
100PBK0.53690740
101PRKD30.53396455
102BRAF0.53219967
103PAK30.51457168
104CHEK10.49824963
105MAPK150.49434980
106AURKA0.48416285
107MET0.48315791
108CDK90.47653933
109MAPK40.47600727
110ATR0.47381961
111CSF1R0.47363147
112MST1R0.47028933
113TBK10.46186511
114EIF2AK10.45666670
115PIK3CG0.44871614
116MAP3K10.43451933
117PLK10.43129764
118TAOK20.42049176
119PRKD20.41524941
120MAPKAPK20.41286889
121RPS6KA20.41134252
122MAPK120.40976589
123MAP3K70.40808318
124MARK20.40736356
125ROCK20.40305205
126MAP2K10.40268002
127AKT20.40022344
128RPS6KA10.38646832
129CDK20.38517936
130PRKG20.38394734
131TYK20.37782980
132TTK0.36060660
133MAPK70.35921377
134PRKD10.34994835
135CDC42BPA0.34431231
136INSR0.34226663
137IKBKE0.33800793
138BTK0.33245097
139HIPK20.32994512
140EPHB10.32795706
141CCNB10.32764633
142RET0.30531316
143CHEK20.29827068
144SRPK10.29510566
145TAOK10.29349656

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045122.75723014
2Ribosome_Homo sapiens_hsa030102.66620025
3Focal adhesion_Homo sapiens_hsa045102.43993089
4DNA replication_Homo sapiens_hsa030302.26193802
5Bacterial invasion of epithelial cells_Homo sapiens_hsa051002.19290216
6Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005322.07255920
7p53 signaling pathway_Homo sapiens_hsa041152.01784624
8Bladder cancer_Homo sapiens_hsa052192.00332876
9Proteoglycans in cancer_Homo sapiens_hsa052051.90833510
10Fanconi anemia pathway_Homo sapiens_hsa034601.89102813
11Adherens junction_Homo sapiens_hsa045201.83622316
12Small cell lung cancer_Homo sapiens_hsa052221.82704593
13AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.81696890
14Cell cycle_Homo sapiens_hsa041101.77484408
15Spliceosome_Homo sapiens_hsa030401.76429682
16TGF-beta signaling pathway_Homo sapiens_hsa043501.70903734
17Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.68536434
18Mismatch repair_Homo sapiens_hsa034301.63232838
19Shigellosis_Homo sapiens_hsa051311.62707174
20MicroRNAs in cancer_Homo sapiens_hsa052061.61752534
21Hippo signaling pathway_Homo sapiens_hsa043901.58772569
22Basal cell carcinoma_Homo sapiens_hsa052171.58133821
23One carbon pool by folate_Homo sapiens_hsa006701.56838513
24Viral myocarditis_Homo sapiens_hsa054161.56405176
25Chronic myeloid leukemia_Homo sapiens_hsa052201.54752899
26RNA transport_Homo sapiens_hsa030131.51622596
27HTLV-I infection_Homo sapiens_hsa051661.44817081
28Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.43138554
29Pentose phosphate pathway_Homo sapiens_hsa000301.42322531
30Leukocyte transendothelial migration_Homo sapiens_hsa046701.41872708
31Protein digestion and absorption_Homo sapiens_hsa049741.40659059
32Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.40006124
33Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.39076724
34PI3K-Akt signaling pathway_Homo sapiens_hsa041511.35489495
35Amoebiasis_Homo sapiens_hsa051461.35405597
36Primary immunodeficiency_Homo sapiens_hsa053401.34704993
37Folate biosynthesis_Homo sapiens_hsa007901.29738440
38Dilated cardiomyopathy_Homo sapiens_hsa054141.28815033
39Viral carcinogenesis_Homo sapiens_hsa052031.28726139
40Base excision repair_Homo sapiens_hsa034101.27818804
41Malaria_Homo sapiens_hsa051441.25933465
42Nucleotide excision repair_Homo sapiens_hsa034201.24898725
43Notch signaling pathway_Homo sapiens_hsa043301.23472061
44Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.20575077
45B cell receptor signaling pathway_Homo sapiens_hsa046621.20446779
46Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.18303776
47Biosynthesis of amino acids_Homo sapiens_hsa012301.15692365
48Regulation of actin cytoskeleton_Homo sapiens_hsa048101.15262594
49Pathways in cancer_Homo sapiens_hsa052001.13500260
50Apoptosis_Homo sapiens_hsa042101.11472175
51Hedgehog signaling pathway_Homo sapiens_hsa043401.07471462
52Thyroid cancer_Homo sapiens_hsa052161.06815841
53Pancreatic cancer_Homo sapiens_hsa052121.05503348
54Melanoma_Homo sapiens_hsa052181.02653679
55Central carbon metabolism in cancer_Homo sapiens_hsa052300.99937134
56Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.99370761
57Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.99007031
58Purine metabolism_Homo sapiens_hsa002300.98725509
59Proteasome_Homo sapiens_hsa030500.97805644
60HIF-1 signaling pathway_Homo sapiens_hsa040660.96804755
61Platelet activation_Homo sapiens_hsa046110.96279750
62Colorectal cancer_Homo sapiens_hsa052100.94841483
63Fructose and mannose metabolism_Homo sapiens_hsa000510.93405945
64Rap1 signaling pathway_Homo sapiens_hsa040150.92478253
65Toxoplasmosis_Homo sapiens_hsa051450.91495257
66TNF signaling pathway_Homo sapiens_hsa046680.89574750
67Glycosaminoglycan degradation_Homo sapiens_hsa005310.87603817
68Acute myeloid leukemia_Homo sapiens_hsa052210.86487575
69Epstein-Barr virus infection_Homo sapiens_hsa051690.85926995
70Transcriptional misregulation in cancer_Homo sapiens_hsa052020.84778403
71Hepatitis B_Homo sapiens_hsa051610.83846107
72Prostate cancer_Homo sapiens_hsa052150.83460502
73Galactose metabolism_Homo sapiens_hsa000520.82817926
74N-Glycan biosynthesis_Homo sapiens_hsa005100.82577095
75Tight junction_Homo sapiens_hsa045300.82015144
762-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.80790125
77RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.80121310
78Antigen processing and presentation_Homo sapiens_hsa046120.78947347
79Salmonella infection_Homo sapiens_hsa051320.78633065
80Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.78168292
81Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.73912459
82Leishmaniasis_Homo sapiens_hsa051400.73431852
83VEGF signaling pathway_Homo sapiens_hsa043700.73317526
84Herpes simplex infection_Homo sapiens_hsa051680.70192602
85Homologous recombination_Homo sapiens_hsa034400.69913003
86Pyrimidine metabolism_Homo sapiens_hsa002400.69844138
87Systemic lupus erythematosus_Homo sapiens_hsa053220.68966615
88Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.68080896
89Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.67738769
90Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.64830913
91Glioma_Homo sapiens_hsa052140.64044880
92Neurotrophin signaling pathway_Homo sapiens_hsa047220.63446528
93RNA polymerase_Homo sapiens_hsa030200.62545320
94Inositol phosphate metabolism_Homo sapiens_hsa005620.61473575
95Wnt signaling pathway_Homo sapiens_hsa043100.60697483
96Glutathione metabolism_Homo sapiens_hsa004800.59025417
97RNA degradation_Homo sapiens_hsa030180.58459860
98Jak-STAT signaling pathway_Homo sapiens_hsa046300.58384940
99Measles_Homo sapiens_hsa051620.58095301
100Legionellosis_Homo sapiens_hsa051340.57431242
101Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.56958414
102Phenylalanine metabolism_Homo sapiens_hsa003600.55231999
103Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.54994679
104Sulfur relay system_Homo sapiens_hsa041220.51745388
105Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.50402739
106Cyanoamino acid metabolism_Homo sapiens_hsa004600.49660622
107Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.49385307
108Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.48904548
109Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.48877948
110Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.48836417
111NF-kappa B signaling pathway_Homo sapiens_hsa040640.47007107
112Carbon metabolism_Homo sapiens_hsa012000.46527930
113Endocytosis_Homo sapiens_hsa041440.45809815
114mTOR signaling pathway_Homo sapiens_hsa041500.44969221
115Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.44852493
116Hematopoietic cell lineage_Homo sapiens_hsa046400.44728280
117Osteoclast differentiation_Homo sapiens_hsa043800.44723929
118Endometrial cancer_Homo sapiens_hsa052130.44345719
119Non-small cell lung cancer_Homo sapiens_hsa052230.43435355
120Renal cell carcinoma_Homo sapiens_hsa052110.42795039
121mRNA surveillance pathway_Homo sapiens_hsa030150.41263192
122Non-homologous end-joining_Homo sapiens_hsa034500.40902171
123Hepatitis C_Homo sapiens_hsa051600.36701856
124Thyroid hormone signaling pathway_Homo sapiens_hsa049190.35741355

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