CCDC109B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)6.38011938
2positive regulation of gamma-delta T cell activation (GO:0046645)5.83597210
3neutrophil activation involved in immune response (GO:0002283)5.82198622
4antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.72339783
5negative regulation of cell killing (GO:0031342)5.43535011
6negative regulation of leukocyte mediated cytotoxicity (GO:0001911)5.43535011
7negative T cell selection (GO:0043383)5.30910179
8negative thymic T cell selection (GO:0045060)5.22263909
9modulation by symbiont of host immune response (GO:0052553)5.11248692
10positive regulation by symbiont of host defense response (GO:0052509)5.11248692
11modulation by symbiont of host defense response (GO:0052031)5.11248692
12modulation by organism of immune response of other organism involved in symbiotic interaction (GO:005.11248692
13modulation by organism of defense response of other organism involved in symbiotic interaction (GO:05.11248692
14positive regulation by organism of defense response of other organism involved in symbiotic interact5.11248692
15regulation of B cell receptor signaling pathway (GO:0050855)5.07057569
16respiratory burst (GO:0045730)4.93756455
17positive regulation of monocyte chemotaxis (GO:0090026)4.88300306
18response to peptidoglycan (GO:0032494)4.61741320
19immunoglobulin mediated immune response (GO:0016064)4.49484290
20regulation of mononuclear cell migration (GO:0071675)4.38027689
21positive regulation of interferon-alpha production (GO:0032727)4.34497751
22regulation of interferon-alpha production (GO:0032647)4.10189513
23regulation of gamma-delta T cell activation (GO:0046643)4.02494655
24tolerance induction (GO:0002507)4.01007663
25regulation of monocyte chemotaxis (GO:0090025)4.00953523
26T cell selection (GO:0045058)3.99545468
27positive T cell selection (GO:0043368)3.95969891
28positive thymic T cell selection (GO:0045059)3.92351170
29regulation of gamma-delta T cell differentiation (GO:0045586)3.91114925
30thymic T cell selection (GO:0045061)3.89926975
31granulocyte activation (GO:0036230)3.89650031
32response to muramyl dipeptide (GO:0032495)3.86874158
33macrophage activation involved in immune response (GO:0002281)3.86236111
34hydrogen peroxide biosynthetic process (GO:0050665)3.83403604
35positive regulation of chemokine biosynthetic process (GO:0045080)3.82305668
36Arp2/3 complex-mediated actin nucleation (GO:0034314)3.80965929
37regulation of T cell tolerance induction (GO:0002664)3.75522050
38interferon-gamma production (GO:0032609)3.73125767
39lipopolysaccharide-mediated signaling pathway (GO:0031663)3.70731148
40positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.70591718
41neutrophil activation (GO:0042119)3.69939645
42cellular response to interleukin-15 (GO:0071350)3.68274729
43positive regulation of interleukin-8 biosynthetic process (GO:0045416)3.68234268
44cellular extravasation (GO:0045123)3.62744085
45myeloid cell activation involved in immune response (GO:0002275)3.62650393
46negative regulation of T cell mediated immunity (GO:0002710)3.62347136
47positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)3.61782747
48eosinophil chemotaxis (GO:0048245)3.60922076
49mast cell activation (GO:0045576)3.60376840
50positive regulation of antigen processing and presentation (GO:0002579)3.59084254
51superoxide anion generation (GO:0042554)3.58369166
52regulation of regulatory T cell differentiation (GO:0045589)3.57437622
53positive regulation of B cell differentiation (GO:0045579)3.56856984
54production of molecular mediator involved in inflammatory response (GO:0002532)3.56556310
55negative regulation of interleukin-12 production (GO:0032695)3.55526010
56regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.53908020
57regulation of natural killer cell mediated immunity (GO:0002715)3.53627531
58regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.53627531
59regulation of interferon-beta biosynthetic process (GO:0045357)3.53386595
60myeloid dendritic cell differentiation (GO:0043011)3.52740908
61regulation of alpha-beta T cell proliferation (GO:0046640)3.51286032
62reactive oxygen species biosynthetic process (GO:1903409)3.46897893
63response to interleukin-15 (GO:0070672)3.44575771
64positive regulation of mast cell activation (GO:0033005)3.42274750
65positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.41755773
66regulation of dendritic cell antigen processing and presentation (GO:0002604)3.40108072
67response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.39852783
68response to host immune response (GO:0052572)3.39852783
69positive regulation of heat generation (GO:0031652)3.37228660
70natural killer cell mediated cytotoxicity (GO:0042267)3.36628713
71natural killer cell mediated immunity (GO:0002228)3.36628713
72myeloid dendritic cell activation (GO:0001773)3.36110295
73positive regulation of mast cell degranulation (GO:0043306)3.34644411
74positive regulation of mast cell activation involved in immune response (GO:0033008)3.34644411
75positive regulation of alpha-beta T cell proliferation (GO:0046641)3.33163490
76B cell mediated immunity (GO:0019724)3.32867964
77regulation of fever generation (GO:0031620)3.32546260
78monocyte chemotaxis (GO:0002548)3.32200295
79regulation of T-helper 1 cell differentiation (GO:0045625)3.30917966
80T cell receptor signaling pathway (GO:0050852)3.29854926
81positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:00610813.29329812
82actin nucleation (GO:0045010)3.27053794
83B cell receptor signaling pathway (GO:0050853)3.26666490
84sequestering of actin monomers (GO:0042989)3.26413483
85NIK/NF-kappaB signaling (GO:0038061)3.25922482
86eosinophil migration (GO:0072677)3.25501357
87antigen receptor-mediated signaling pathway (GO:0050851)3.24641897
88regulation of T cell mediated cytotoxicity (GO:0001914)3.21306595
89regulation of tolerance induction (GO:0002643)3.20789088
90regulation of B cell differentiation (GO:0045577)3.20443495
91regulation of antigen processing and presentation (GO:0002577)3.19781351
92regulation of leukocyte mediated cytotoxicity (GO:0001910)3.19702559
93phagosome maturation (GO:0090382)3.19642638
94T cell costimulation (GO:0031295)3.18348251
95positive regulation of granulocyte differentiation (GO:0030854)3.17186428
96regulation of isotype switching to IgG isotypes (GO:0048302)3.14084271
97lymphocyte chemotaxis (GO:0048247)3.13938681
98lymphocyte costimulation (GO:0031294)3.13912777
99positive regulation of natural killer cell mediated immunity (GO:0002717)3.13163406
100negative regulation of lymphocyte mediated immunity (GO:0002707)3.12804029
101positive regulation of macrophage differentiation (GO:0045651)3.11687332
102positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)3.11421280
103regulation of syncytium formation by plasma membrane fusion (GO:0060142)3.10974352
104mature B cell differentiation involved in immune response (GO:0002313)3.10298515
105negative regulation of myeloid cell apoptotic process (GO:0033033)3.08429229
106regulation of interleukin-2 biosynthetic process (GO:0045076)3.08199312
107antigen processing and presentation of endogenous antigen (GO:0019883)3.06354882
108leukocyte mediated cytotoxicity (GO:0001909)3.04367704
109response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.03226409
110response to host (GO:0075136)3.03226409
111response to host defenses (GO:0052200)3.03226409
112positive regulation of interleukin-2 production (GO:0032743)3.02645822
113positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)3.02611484
114positive regulation of interleukin-12 production (GO:0032735)3.02236987
115regulation of chemokine biosynthetic process (GO:0045073)3.01262543
116regulation of vitamin D biosynthetic process (GO:0060556)3.01124870
117positive regulation of leukocyte mediated cytotoxicity (GO:0001912)2.98298569
118regulation of mast cell degranulation (GO:0043304)2.97360130
119positive regulation of interferon-beta production (GO:0032728)2.96786270
120regulation of T cell receptor signaling pathway (GO:0050856)2.96036672
121regulation of cell killing (GO:0031341)2.95427894
122leukocyte aggregation (GO:0070486)2.93681000
123interferon-gamma-mediated signaling pathway (GO:0060333)2.92998673
124regulation of histone phosphorylation (GO:0033127)2.92723583
125positive regulation of tolerance induction (GO:0002645)2.92303342
126cellular response to zinc ion (GO:0071294)2.91655778
127positive regulation of T-helper 1 type immune response (GO:0002827)2.91356244
128regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.91323943
129positive regulation of T cell mediated cytotoxicity (GO:0001916)2.90643198
130positive regulation of humoral immune response (GO:0002922)2.90155610
131positive regulation of chemokine production (GO:0032722)2.88000690
132dendritic cell differentiation (GO:0097028)2.87469789
133microglial cell activation (GO:0001774)2.87224658
134myeloid leukocyte activation (GO:0002274)2.87123162
135regulation of mast cell activation (GO:0033003)2.85512267
136positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)2.85294196
137alpha-beta T cell differentiation (GO:0046632)2.85175769
138positive regulation of tumor necrosis factor production (GO:0032760)2.84977469
139positive regulation of cellular amide metabolic process (GO:0034250)2.84557032
140detection of molecule of bacterial origin (GO:0032490)2.84342877
141macrophage activation (GO:0042116)2.83563453
142cellular response to type I interferon (GO:0071357)2.82671306
143type I interferon signaling pathway (GO:0060337)2.82671306
144antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.82631373
145antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.82631373
146wound healing, spreading of epidermal cells (GO:0035313)2.82545806
147positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.81277889
148positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.79251444
149negative regulation of T cell apoptotic process (GO:0070233)2.79076841
150Peyers patch development (GO:0048541)2.78613879
151mucosal-associated lymphoid tissue development (GO:0048537)2.78613879
152cellular defense response (GO:0006968)2.78461027
153alpha-beta T cell activation (GO:0046631)2.78399981
154positive regulation of natural killer cell differentiation (GO:0032825)2.78258453
155response to type I interferon (GO:0034340)2.77970635
156positive regulation of acute inflammatory response (GO:0002675)2.77093648
157detection of other organism (GO:0098543)2.76599160
158regulation of mast cell activation involved in immune response (GO:0033006)2.76596989
159negative regulation of interleukin-17 production (GO:0032700)2.75330335
160mast cell degranulation (GO:0043303)2.75251027
161mast cell activation involved in immune response (GO:0002279)2.75251027
162T cell migration (GO:0072678)2.75092568
163detection of bacterium (GO:0016045)2.73858126
164lymphocyte migration (GO:0072676)2.73218313
165mature B cell differentiation (GO:0002335)2.72936668
166positive regulation of cell killing (GO:0031343)2.72705620
167T cell differentiation (GO:0030217)2.71745196

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* IRF8_21731497_ChIP-ChIP_J774_Mouse6.74733060
2BP1_19119308_ChIP-ChIP_Hs578T_Human6.01984712
3IRF8_22096565_ChIP-ChIP_GC-B_Human5.70811934
4* IRF8_27001747_Chip-Seq_BMDM_Mouse4.37768508
5SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse4.22272161
6ELF1_17652178_ChIP-ChIP_JURKAT_Human3.90243578
7Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse3.85168704
8NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse3.76262035
9IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.71751069
10SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.42649437
11* MYB_21317192_ChIP-Seq_ERMYB_Mouse3.41315136
12* MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.33473898
13RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human3.19324429
14EGR1_19374776_ChIP-ChIP_THP-1_Human3.15949502
15FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.07991960
16IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.00312202
17SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.68448644
18NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.61196864
19STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.60602125
20STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.55662657
21STAT4_19710469_ChIP-ChIP_TH1__Mouse2.53367481
22NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.30246998
23CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.29419759
24SPI1_23547873_ChIP-Seq_NB4_Human2.28770069
25BRD4_27068464_Chip-Seq_AML-cells_Mouse2.19543590
26VDR_23849224_ChIP-Seq_CD4+_Human2.08937920
27PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse2.01376934
28RARG_19884340_ChIP-ChIP_MEFs_Mouse1.89840608
29CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.86628778
30CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.86626271
31GABP_17652178_ChIP-ChIP_JURKAT_Human1.86581252
32VDR_24763502_ChIP-Seq_THP-1_Human1.86055087
33MYC_22102868_ChIP-Seq_BL_Human1.82171310
34* MYB_26560356_Chip-Seq_TH2_Human1.81310069
35TP63_17297297_ChIP-ChIP_HaCaT_Human1.79782209
36TRIM28_21343339_ChIP-Seq_HEK293_Human1.76143841
37RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.75637025
38PU_27001747_Chip-Seq_BMDM_Mouse1.73666233
39RUNX1_22412390_ChIP-Seq_EML_Mouse1.69635058
40STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.68870286
41CIITA_25753668_ChIP-Seq_RAJI_Human1.67738233
42NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.66890298
43ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.66739327
44NOTCH1_21737748_ChIP-Seq_TLL_Human1.64882855
45VDR_24787735_ChIP-Seq_THP-1_Human1.63779928
46FOXP3_21729870_ChIP-Seq_TREG_Human1.62574924
47CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.62535221
48* SPI1_23127762_ChIP-Seq_K562_Human1.60529157
49SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.59936850
50STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.58834651
51MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.58717246
52RUNX_20019798_ChIP-Seq_JUKART_Human1.57855279
53FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.56438210
54CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.55273932
55PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.51682163
56PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.47360884
57THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.46783422
58FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.45943793
59EST1_17652178_ChIP-ChIP_JURKAT_Human1.45857226
60JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.43581506
61MAF_26560356_Chip-Seq_TH1_Human1.43425869
62* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.36102295
63FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.35679519
64TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.33968807
65ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.32151741
66RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.30931705
67SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.30263653
68CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.28712342
69EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.27652452
70SMAD_19615063_ChIP-ChIP_OVARY_Human1.25828564
71VDR_21846776_ChIP-Seq_THP-1_Human1.25017683
72MYB_26560356_Chip-Seq_TH1_Human1.23528401
73PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.23082030
74KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.22157546
75ETS1_20019798_ChIP-Seq_JURKAT_Human1.20866930
76NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.19267656
77ERG_20887958_ChIP-Seq_HPC-7_Mouse1.15803319
78ELK3_25401928_ChIP-Seq_HUVEC_Human1.14772075
79GATA3_27048872_Chip-Seq_THYMUS_Human1.13710993
80GATA3_26560356_Chip-Seq_TH2_Human1.12620828
81FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.12017116
82* NRF2_20460467_ChIP-Seq_MEFs_Mouse1.10199535
83* NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.10199535
84BCL6_27268052_Chip-Seq_Bcells_Human1.09456436
85TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.07525972
86SRF_21415370_ChIP-Seq_HL-1_Mouse1.06182925
87CJUN_26792858_Chip-Seq_BT549_Human1.05517084
88SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.05200188
89FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.04943836
90CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.04807054
91UTX_26944678_Chip-Seq_JUKART_Human1.04317055
92CREB1_15753290_ChIP-ChIP_HEK293T_Human1.03776834
93JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.02674125
94VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.01045322
95GATA2_21666600_ChIP-Seq_HMVEC_Human1.00731379
96GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.00727041
97HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.00460559
98LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.00076901
99SOX2_20726797_ChIP-Seq_SW620_Human0.99422587
100PU.1_20513432_ChIP-Seq_Bcells_Mouse0.98758386
101TFEB_21752829_ChIP-Seq_HELA_Human0.98107021
102GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.97704147
103RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.97314197
104GATA2_22383799_ChIP-Seq_G1ME_Mouse0.96382908
105JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.93441153
106E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.89469050
107SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.89292991
108* SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.89074468
109* SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.89074468
110GABP_19822575_ChIP-Seq_HepG2_Human0.85848162
111IKZF1_21737484_ChIP-ChIP_HCT116_Human0.84739863
112RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.84618057
113MYC_18358816_ChIP-ChIP_MESCs_Mouse0.81747196
114ELF1_20517297_ChIP-Seq_JURKAT_Human0.81298680
115KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.80115236
116LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.79870162
117PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.79244384
118ELK1_19687146_ChIP-ChIP_HELA_Human0.79154005
119* MAF_26560356_Chip-Seq_TH2_Human0.79030162
120CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.78548042
121RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.76025736
122STAT1_20625510_ChIP-Seq_HELA_Human0.75766154
123HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.75578045
124HOXB4_20404135_ChIP-ChIP_EML_Mouse0.75302493
125P63_26484246_Chip-Seq_KERATINOCYTES_Human0.74820861
126ELK1_22589737_ChIP-Seq_MCF10A_Human0.74211373
127EGR1_19032775_ChIP-ChIP_M12_Human0.73539474
128TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.72314107
129SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.71207108
130SPI1_20517297_ChIP-Seq_HL60_Human0.69656274
131VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.69535753
132FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.69028030
133CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.68563909
134FOXM1_23109430_ChIP-Seq_U2OS_Human0.68129496
135SCL_19346495_ChIP-Seq_HPC-7_Human0.68043995
136CDX2_19796622_ChIP-Seq_MESCs_Mouse0.67683213
137GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.66667333

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.33693687
2MP0003436_decreased_susceptibility_to4.13215176
3MP0003303_peritoneal_inflammation3.83718950
4MP0002148_abnormal_hypersensitivity_rea3.69322597
5MP0009785_altered_susceptibility_to3.42935892
6MP0005000_abnormal_immune_tolerance3.18372048
7MP0002419_abnormal_innate_immunity3.14431730
8MP0006082_CNS_inflammation3.05494482
9MP0004510_myositis2.88214897
10MP0005025_abnormal_response_to2.76527208
11MP0003724_increased_susceptibility_to2.66296163
12MP0005058_abnormal_lysosome_morphology2.61261113
13MP0002452_abnormal_antigen_presenting2.49993757
14MP0000685_abnormal_immune_system2.47656091
15MP0005387_immune_system_phenotype2.47422697
16MP0001790_abnormal_immune_system2.47422697
17MP0005671_abnormal_response_to2.32173758
18MP0002723_abnormal_immune_serum2.30480539
19MP0001533_abnormal_skeleton_physiology2.29644336
20MP0001800_abnormal_humoral_immune2.20004286
21MP0001819_abnormal_immune_cell2.10257820
22MP0002420_abnormal_adaptive_immunity2.07201360
23MP0009333_abnormal_splenocyte_physiolog2.00794061
24MP0002405_respiratory_system_inflammati2.00290809
25MP0003448_altered_tumor_morphology1.98847019
26MP0005464_abnormal_platelet_physiology1.97820237
27MP0000343_altered_response_to1.95455669
28MP0000703_abnormal_thymus_morphology1.93622427
29MP0000858_altered_metastatic_potential1.85239373
30MP0001845_abnormal_inflammatory_respons1.82138702
31MP0005310_abnormal_salivary_gland1.77731216
32MP0008438_abnormal_cutaneous_collagen1.76205084
33MP0009764_decreased_sensitivity_to1.75318004
34MP0001853_heart_inflammation1.71389623
35MP0000465_gastrointestinal_hemorrhage1.69639024
36MP0002998_abnormal_bone_remodeling1.69088742
37MP0002006_tumorigenesis1.66061814
38MP0004947_skin_inflammation1.64826204
39MP0003075_altered_response_to1.62223449
40MP0003300_gastrointestinal_ulcer1.60423497
41MP0010386_abnormal_urinary_bladder1.58181739
42MP0003183_abnormal_peptide_metabolism1.53737338
43MP0010155_abnormal_intestine_physiology1.48212533
44MP0005166_decreased_susceptibility_to1.47617694
45MP0002009_preneoplasia1.46475397
46MP0001873_stomach_inflammation1.46409137
47MP0003172_abnormal_lysosome_physiology1.45344268
48MP0000716_abnormal_immune_system1.44381108
49MP0008469_abnormal_protein_level1.43085568
50MP0000604_amyloidosis1.39775620
51MP0005075_abnormal_melanosome_morpholog1.37698127
52MP0002163_abnormal_gland_morphology1.32671446
53MP0002398_abnormal_bone_marrow1.31994683
54MP0005390_skeleton_phenotype1.29148161
55MP0003186_abnormal_redox_activity1.26642480
56MP0006054_spinal_hemorrhage1.25128693
57MP0005397_hematopoietic_system_phenotyp1.23034276
58MP0001545_abnormal_hematopoietic_system1.23034276
59MP0005076_abnormal_cell_differentiation1.21622126
60MP0001542_abnormal_bone_strength1.21384281
61MP0003279_aneurysm1.21088198
62MP0002933_joint_inflammation1.19622726
63MP0005257_abnormal_intraocular_pressure1.19456996
64MP0003566_abnormal_cell_adhesion1.18445922
65MP0008260_abnormal_autophagy1.17329320
66MP0005164_abnormal_response_to1.15370396
67MP0010307_abnormal_tumor_latency1.14883856
68MP0002429_abnormal_blood_cell1.13249631
69MP0001851_eye_inflammation1.09735168
70MP0003806_abnormal_nucleotide_metabolis1.09014410
71MP0000689_abnormal_spleen_morphology1.08915044
72MP0002877_abnormal_melanocyte_morpholog1.08043944
73MP0002166_altered_tumor_susceptibility1.07936257
74MP0002722_abnormal_immune_system1.06339162
75MP0004858_abnormal_nervous_system1.02556745
76MP0003091_abnormal_cell_migration1.01302091
77MP0009278_abnormal_bone_marrow0.98524167
78MP0009840_abnormal_foam_cell0.98180290
79MP0003191_abnormal_cellular_cholesterol0.95845575
80MP0002019_abnormal_tumor_incidence0.94710227
81MP0003828_pulmonary_edema0.94531341
82MP0000569_abnormal_digit_pigmentation0.92767152
83MP0003705_abnormal_hypodermis_morpholog0.92313661
84MP0005174_abnormal_tail_pigmentation0.90611226
85MP0004381_abnormal_hair_follicle0.88778743
86MP0002132_abnormal_respiratory_system0.87578425
87MP0003795_abnormal_bone_structure0.87041173
88MP0000249_abnormal_blood_vessel0.86505013
89MP0004782_abnormal_surfactant_physiolog0.85918026
90MP0003656_abnormal_erythrocyte_physiolo0.85861974
91MP0002138_abnormal_hepatobiliary_system0.84675538
92MP0009763_increased_sensitivity_to0.82837984
93MP0000372_irregular_coat_pigmentation0.81057359
94MP0010352_gastrointestinal_tract_polyps0.80027376
95MP0003690_abnormal_glial_cell0.77040261
96MP0004883_abnormal_blood_vessel0.76387298
97MP0000490_abnormal_crypts_of0.75623957
98MP0002295_abnormal_pulmonary_circulatio0.75352908
99MP0005451_abnormal_body_composition0.74262094
100MP0002693_abnormal_pancreas_physiology0.74141493
101MP0003045_fibrosis0.74010848
102MP0001663_abnormal_digestive_system0.71746075
103MP0001958_emphysema0.69888857
104MP0005408_hypopigmentation0.69059876
105MP0009765_abnormal_xenobiotic_induced0.68727748
106MP0001986_abnormal_taste_sensitivity0.68454206
107MP0001348_abnormal_lacrimal_gland0.66971173
108MP0005379_endocrine/exocrine_gland_phen0.66950297
109MP0005197_abnormal_uvea_morphology0.65701615
110MP0005167_abnormal_blood-brain_barrier0.64942001
111MP0003763_abnormal_thymus_physiology0.64874245
112MP0002136_abnormal_kidney_physiology0.64796125
113MP0005023_abnormal_wound_healing0.64066311
114MP0003453_abnormal_keratinocyte_physiol0.63844172
115MP0002277_abnormal_respiratory_mucosa0.63160112
116MP0001919_abnormal_reproductive_system0.62792278
117MP0000015_abnormal_ear_pigmentation0.62246694
118MP0006072_abnormal_retinal_apoptosis0.60128394
119MP0002396_abnormal_hematopoietic_system0.59497234
120MP0003866_abnormal_defecation0.58436430
121MP0002653_abnormal_ependyma_morphology0.57450585
122MP0004808_abnormal_hematopoietic_stem0.57195992
123MP0001764_abnormal_homeostasis0.55278613
124MP0008873_increased_physiological_sensi0.49897841
125MP0001243_abnormal_dermal_layer0.47882277
126MP0006036_abnormal_mitochondrial_physio0.42971631
127MP0003786_premature_aging0.42060095

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)7.34269020
2Eczematoid dermatitis (HP:0000976)7.33236602
3Recurrent bacterial skin infections (HP:0005406)6.64267662
4Recurrent gram-negative bacterial infections (HP:0005420)6.01524952
5T lymphocytopenia (HP:0005403)5.01075296
6Severe combined immunodeficiency (HP:0004430)4.81051110
7Systemic lupus erythematosus (HP:0002725)4.77037804
8Abnormality of macrophages (HP:0004311)4.75692611
9Abnormality of T cell number (HP:0011839)4.75459789
10Mediastinal lymphadenopathy (HP:0100721)4.69850835
11IgG deficiency (HP:0004315)4.51343814
12Vacuolated lymphocytes (HP:0001922)4.47722484
13Elevated erythrocyte sedimentation rate (HP:0003565)4.29369036
14Panhypogammaglobulinemia (HP:0003139)4.23349179
15Autoimmune hemolytic anemia (HP:0001890)4.19139004
16Increased cerebral lipofuscin (HP:0011813)4.13369842
17Combined immunodeficiency (HP:0005387)4.12250943
18Myositis (HP:0100614)4.09553772
19Abnormality of B cell number (HP:0010975)4.01122811
20Recurrent skin infections (HP:0001581)4.00406888
21Obstructive lung disease (HP:0006536)3.90502548
22Chronic obstructive pulmonary disease (HP:0006510)3.90502548
23Abnormality of T cells (HP:0002843)3.89323453
24Axonal loss (HP:0003447)3.88501185
25B lymphocytopenia (HP:0010976)3.87513487
26Orchitis (HP:0100796)3.85077977
27Increased neuronal autofluorescent lipopigment (HP:0002074)3.85001619
28Gingivitis (HP:0000230)3.73319868
29Encephalitis (HP:0002383)3.67377366
30Recurrent fungal infections (HP:0002841)3.64568609
31Prostate neoplasm (HP:0100787)3.56469496
32Eosinophilia (HP:0001880)3.54107672
33Granulocytopenia (HP:0001913)3.51857905
34Autoimmune thrombocytopenia (HP:0001973)3.51494632
35Agammaglobulinemia (HP:0004432)3.48506786
36Retrobulbar optic neuritis (HP:0100654)3.45812411
37Optic neuritis (HP:0100653)3.45812411
38Abnormality of eosinophils (HP:0001879)3.43581990
39Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)3.42809051
40Abnormal delayed hypersensitivity skin test (HP:0002963)3.36938186
41Thyroiditis (HP:0100646)3.23708206
42Cellulitis (HP:0100658)3.22734793
43IgM deficiency (HP:0002850)3.16483335
44Disinhibition (HP:0000734)3.08764021
45Stomatitis (HP:0010280)3.08538853
46Vasculitis (HP:0002633)3.05835453
47Lymphopenia (HP:0001888)3.02671765
48Vertebral compression fractures (HP:0002953)3.02462451
49Basal ganglia calcification (HP:0002135)3.01154104
50Abnormality of glycolipid metabolism (HP:0010969)2.97395002
51Abnormality of liposaccharide metabolism (HP:0010968)2.97395002
52Abnormality of glycosphingolipid metabolism (HP:0004343)2.97395002
53Abnormality of T cell physiology (HP:0011840)2.97093430
54Dysostosis multiplex (HP:0000943)2.93704447
55Recurrent bronchitis (HP:0002837)2.86894270
56Abnormality of cells of the lymphoid lineage (HP:0012140)2.84808438
57Peritonitis (HP:0002586)2.78672754
58Glomerulonephritis (HP:0000099)2.75593784
59Urticaria (HP:0001025)2.70413511
60Chronic mucocutaneous candidiasis (HP:0002728)2.67297381
61Recurrent cutaneous fungal infections (HP:0011370)2.67297381
62Recurrent viral infections (HP:0004429)2.64949974
63Lymphoma (HP:0002665)2.62692997
64Chronic diarrhea (HP:0002028)2.59962999
65Pulmonary infiltrates (HP:0002113)2.59404278
66Interstitial pulmonary disease (HP:0006530)2.57873689
67Hypoproteinemia (HP:0003075)2.56792387
68Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.56760587
69Inflammation of the large intestine (HP:0002037)2.55542415
70Pustule (HP:0200039)2.53075493
71Myocardial infarction (HP:0001658)2.51019916
72Recurrent pneumonia (HP:0006532)2.48750292
73Thick nail (HP:0001805)2.46106739
743-Methylglutaconic aciduria (HP:0003535)2.45757578
75Increased IgM level (HP:0003496)2.45495507
76Osteomyelitis (HP:0002754)2.42407454
77Periodontitis (HP:0000704)2.41800545
78Verrucae (HP:0200043)2.40902619
79Papilloma (HP:0012740)2.40902619
80Gastrointestinal inflammation (HP:0004386)2.39016162
81Hypoplasia of the thymus (HP:0000778)2.36543076
82Tetraparesis (HP:0002273)2.34489911
83Neoplasm of head and neck (HP:0012288)2.33563968
84Esophageal neoplasm (HP:0100751)2.33563968
85Osteolytic defects of the hand bones (HP:0009699)2.32666608
86Osteolytic defects of the phalanges of the hand (HP:0009771)2.32666608
87Meningitis (HP:0001287)2.31462617
88Urinary glycosaminoglycan excretion (HP:0003541)2.31133623
89Mucopolysacchariduria (HP:0008155)2.31133623
90Petechiae (HP:0000967)2.30755043
91Poor head control (HP:0002421)2.28713583
92Gastrointestinal stroma tumor (HP:0100723)2.28520429
93Hypergammaglobulinemia (HP:0010702)2.28201739
94Arterial thrombosis (HP:0004420)2.26761834
95Colitis (HP:0002583)2.26665929
96Leukocytosis (HP:0001974)2.23909215
97Chest pain (HP:0100749)2.23011898
98Recurrent sinusitis (HP:0011108)2.22633503
99Acute hepatic failure (HP:0006554)2.21960957
100Gangrene (HP:0100758)2.20355174
101Recurrent lower respiratory tract infections (HP:0002783)2.17916930
102Aplastic anemia (HP:0001915)2.17203563
103IgA deficiency (HP:0002720)2.14936909
104Joint swelling (HP:0001386)2.12430387
105Abnormality of the pleura (HP:0002103)2.11781287
106Abnormality of mucopolysaccharide metabolism (HP:0011020)2.10536629
107Abnormality of polysaccharide metabolism (HP:0011012)2.10536629
108Abnormality of glycosaminoglycan metabolism (HP:0004371)2.10536629
109Abnormality of the lumbar spine (HP:0100712)2.09650345
110Agnosia (HP:0010524)2.08913599
111Abnormality of the prostate (HP:0008775)2.08839658
112Gastrointestinal infarctions (HP:0005244)2.07545541
113Hemoptysis (HP:0002105)2.05190620
114Nephritis (HP:0000123)2.04405101
115Segmental peripheral demyelination/remyelination (HP:0003481)2.04294484
116Bone pain (HP:0002653)2.02425631
117Bone cyst (HP:0012062)1.99532492
118Pathologic fracture (HP:0002756)1.97234171
119Abnormality of the pericardium (HP:0001697)1.95016424
120Polyneuropathy (HP:0001271)1.93828145
121Loss of speech (HP:0002371)1.91865061
122Glomerulopathy (HP:0100820)1.89247477
123Abnormality of complement system (HP:0005339)1.89004294
124Fatigue (HP:0012378)1.88531939
125Aplasia/Hypoplasia of the thymus (HP:0010515)1.87976937
126Anorexia (HP:0002039)1.86278344
127Skin rash (HP:0000988)1.85872561
128Thrombocytosis (HP:0001894)1.83363524
129Epistaxis (HP:0000421)1.81916187
130Nasal polyposis (HP:0100582)1.81170522
131Chronic otitis media (HP:0000389)1.80829844
132Neutropenia (HP:0001875)1.80373782
133Chronic sinusitis (HP:0011109)1.79659728
134Bronchitis (HP:0012387)1.79013019
135Keratoconjunctivitis sicca (HP:0001097)1.78856751
136Hepatosplenomegaly (HP:0001433)1.78016877
137Sepsis (HP:0100806)1.75660111
138Spontaneous hematomas (HP:0007420)1.75434272
139Premature loss of primary teeth (HP:0006323)1.75429501
140Skin ulcer (HP:0200042)1.75400185
141Stomach cancer (HP:0012126)1.74832693
142Arthralgia (HP:0002829)1.73956190
143Beaking of vertebral bodies (HP:0004568)1.73926427
144Alveolar cell carcinoma (HP:0006519)1.73596433
145Diminished motivation (HP:0000745)1.72729786
146J-shaped sella turcica (HP:0002680)1.71143529
147Anhidrosis (HP:0000970)1.70964620
148Porencephaly (HP:0002132)1.70805329
149Thoracic kyphosis (HP:0002942)1.69966779
150Keratoconjunctivitis (HP:0001096)1.68526001
151Spondylolisthesis (HP:0003302)1.67571484
152Hematochezia (HP:0002573)1.67494913
153Increased IgE level (HP:0003212)1.62124239

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K143.83071559
2BLK3.81819474
3NME23.75747781
4RIPK43.72304104
5PIM23.28413199
6PBK3.09067680
7TBK12.88301545
8PASK2.51722618
9MAP4K12.27709474
10IRAK42.27000856
11TYK22.24109683
12GRK62.18659989
13JAK32.02213689
14ERN12.00159585
15ABL21.96468451
16IKBKB1.93425862
17TXK1.82846427
18KDR1.81917962
19TESK11.79144862
20ZAP701.76118121
21ARAF1.74948856
22IKBKE1.74878847
23NEK91.64303294
24KIT1.63834301
25TLK11.61977508
26TAOK31.58354494
27SCYL21.58305850
28MAP3K111.40468436
29MAP3K131.35196356
30MOS1.34286511
31IRAK31.33652357
32TRPM71.31557932
33CAMKK11.30753486
34PRPF4B1.29098104
35JAK11.28709252
36BMPR21.27649604
37TESK21.26622601
38SYK1.25726671
39MST41.24764028
40HCK1.24458832
41CSK1.18982554
42RPS6KA41.18730120
43EPHB11.17177629
44CDK191.10622549
45BMX1.08279453
46CHUK1.02681039
47BTK1.02469122
48LIMK11.01509247
49GRK71.00333846
50TNK20.96224204
51LYN0.94796130
52PIM10.94578714
53STK100.94249812
54NLK0.93805592
55TEC0.93255571
56LCK0.92374205
57KSR20.90658175
58TTN0.90467007
59MAP2K30.88960962
60FGR0.88807072
61FES0.88536981
62VRK20.88448227
63JAK20.88361310
64CSF1R0.87652126
65ZAK0.87626976
66EIF2AK30.86020617
67EPHA30.84213773
68MAP3K50.80138071
69MATK0.77461502
70MARK30.77347342
71CAMKK20.77239032
72BCKDK0.76103144
73LRRK20.75331307
74FGFR30.74637448
75MST1R0.73938654
76ERBB40.73544454
77NTRK10.72942160
78VRK10.70572015
79ABL10.70502356
80MAP3K30.69336390
81MAP3K10.67569715
82TAOK20.66896617
83EIF2AK20.66850474
84ERBB30.64753789
85GRK50.63066609
86YES10.62632834
87TAOK10.61898147
88CDK60.60089365
89STK40.59484492
90PRKCD0.58962887
91TGFBR20.57929168
92MAP3K100.56877808
93SIK20.56093475
94DAPK30.53347094
95CDK40.53229002
96EGFR0.51889709
97MAP3K120.51796269
98MAPKAPK20.51793165
99IRAK10.51758618
100MAPK110.50955235
101RAF10.48663798
102HIPK20.46928942
103RPS6KA50.44934334
104DMPK0.43804175
105ADRBK20.41098953
106PIK3CG0.40826047
107MAP4K20.39651913
108TRIM280.38413966
109CLK10.37855099
110TRIB30.37593249
111ILK0.36474734
112RIPK10.35981363
113SIK30.35732157
114ITK0.35364887
115BRAF0.34754354
116MAP3K80.34649752
117TIE10.33919359
118PAK40.33422581
119MAPK70.33344699
120MAP2K10.33295427
121RPS6KA60.32042570
122PTK2B0.31984299
123PAK10.29635224
124MAP2K20.29500518
125PRKCQ0.28806553
126FYN0.27133377
127NUAK10.27063170
128DAPK10.25046415
129PDK10.23132129
130IGF1R0.21833697
131INSR0.20615875
132STK240.20195912

Predicted pathways (KEGG)

RankGene SetZ-score
1Leishmaniasis_Homo sapiens_hsa051403.48068837
2Graft-versus-host disease_Homo sapiens_hsa053322.84057892
3Rheumatoid arthritis_Homo sapiens_hsa053232.57901993
4Staphylococcus aureus infection_Homo sapiens_hsa051502.52923375
5Phagosome_Homo sapiens_hsa041452.50430393
6Toll-like receptor signaling pathway_Homo sapiens_hsa046202.44751994
7Pertussis_Homo sapiens_hsa051332.44619239
8Osteoclast differentiation_Homo sapiens_hsa043802.44075814
9Legionellosis_Homo sapiens_hsa051342.40381326
10Tuberculosis_Homo sapiens_hsa051522.39762350
11Malaria_Homo sapiens_hsa051442.26266359
12NOD-like receptor signaling pathway_Homo sapiens_hsa046212.22741268
13NF-kappa B signaling pathway_Homo sapiens_hsa040642.19518044
14Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.10090015
15Salmonella infection_Homo sapiens_hsa051322.09377189
16Ribosome_Homo sapiens_hsa030102.08391114
17Lysosome_Homo sapiens_hsa041422.07050409
18Shigellosis_Homo sapiens_hsa051311.89719961
19Allograft rejection_Homo sapiens_hsa053301.83957164
20Measles_Homo sapiens_hsa051621.79091869
21TNF signaling pathway_Homo sapiens_hsa046681.76401455
22Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.71954546
23Other glycan degradation_Homo sapiens_hsa005111.69394125
24Asthma_Homo sapiens_hsa053101.68067424
25Type I diabetes mellitus_Homo sapiens_hsa049401.62080525
26Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.60158682
27Intestinal immune network for IgA production_Homo sapiens_hsa046721.56712696
28Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.52839796
29RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.51802929
30Apoptosis_Homo sapiens_hsa042101.50909688
31Toxoplasmosis_Homo sapiens_hsa051451.48473624
32Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.47172345
33Influenza A_Homo sapiens_hsa051641.46831507
34Collecting duct acid secretion_Homo sapiens_hsa049661.42825745
35Hematopoietic cell lineage_Homo sapiens_hsa046401.42128617
36Chemokine signaling pathway_Homo sapiens_hsa040621.32320551
37Antigen processing and presentation_Homo sapiens_hsa046121.29820242
38Glycosaminoglycan degradation_Homo sapiens_hsa005311.29237912
39Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.28322041
40Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.25130313
41Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.23540202
42B cell receptor signaling pathway_Homo sapiens_hsa046621.23221979
43African trypanosomiasis_Homo sapiens_hsa051431.15433528
44Hepatitis B_Homo sapiens_hsa051611.11841631
45AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.11421021
46Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.10710629
47Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.08075790
48Jak-STAT signaling pathway_Homo sapiens_hsa046301.05775971
49Herpes simplex infection_Homo sapiens_hsa051681.04702190
50Viral myocarditis_Homo sapiens_hsa054161.04356650
51Vibrio cholerae infection_Homo sapiens_hsa051101.01479724
52Amoebiasis_Homo sapiens_hsa051461.01060760
53Proteasome_Homo sapiens_hsa030501.00389005
54Systemic lupus erythematosus_Homo sapiens_hsa053221.00060212
55Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.97176493
56Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.93191080
57Regulation of autophagy_Homo sapiens_hsa041400.91830922
58Leukocyte transendothelial migration_Homo sapiens_hsa046700.91666667
59Prion diseases_Homo sapiens_hsa050200.90495693
60Autoimmune thyroid disease_Homo sapiens_hsa053200.90199033
61Pancreatic cancer_Homo sapiens_hsa052120.85379500
62DNA replication_Homo sapiens_hsa030300.83005785
63T cell receptor signaling pathway_Homo sapiens_hsa046600.74542113
64Chronic myeloid leukemia_Homo sapiens_hsa052200.73718826
65SNARE interactions in vesicular transport_Homo sapiens_hsa041300.70451564
66Neurotrophin signaling pathway_Homo sapiens_hsa047220.69674812
67Platelet activation_Homo sapiens_hsa046110.68676306
68Epstein-Barr virus infection_Homo sapiens_hsa051690.68327245
69RNA polymerase_Homo sapiens_hsa030200.67401837
70Hepatitis C_Homo sapiens_hsa051600.67167375
71Spliceosome_Homo sapiens_hsa030400.65371753
72Acute myeloid leukemia_Homo sapiens_hsa052210.64662088
73Pyrimidine metabolism_Homo sapiens_hsa002400.64468924
74Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.62893242
75HIF-1 signaling pathway_Homo sapiens_hsa040660.62438608
76Prolactin signaling pathway_Homo sapiens_hsa049170.61245304
77Base excision repair_Homo sapiens_hsa034100.61031922
78Primary immunodeficiency_Homo sapiens_hsa053400.60782693
79Parkinsons disease_Homo sapiens_hsa050120.59639336
80Viral carcinogenesis_Homo sapiens_hsa052030.59243415
81Endocytosis_Homo sapiens_hsa041440.56130483
82Homologous recombination_Homo sapiens_hsa034400.53600156
83Regulation of actin cytoskeleton_Homo sapiens_hsa048100.53459219
84VEGF signaling pathway_Homo sapiens_hsa043700.50463226
85Complement and coagulation cascades_Homo sapiens_hsa046100.49828675
86Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.48121093
87Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.46625623
88Mineral absorption_Homo sapiens_hsa049780.45778124
89Sphingolipid signaling pathway_Homo sapiens_hsa040710.45744467
90Mismatch repair_Homo sapiens_hsa034300.45395720
91p53 signaling pathway_Homo sapiens_hsa041150.42616813
92Transcriptional misregulation in cancer_Homo sapiens_hsa052020.40904043
93Proteoglycans in cancer_Homo sapiens_hsa052050.40731054
94Synaptic vesicle cycle_Homo sapiens_hsa047210.39153152
95Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.36185033
96Fatty acid elongation_Homo sapiens_hsa000620.36121213
97Fanconi anemia pathway_Homo sapiens_hsa034600.36113827
98RNA degradation_Homo sapiens_hsa030180.35824803
99Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.34342953
100Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.33761030
101Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.32908801
102Steroid biosynthesis_Homo sapiens_hsa001000.31573859
103Sphingolipid metabolism_Homo sapiens_hsa006000.30298050
104Protein export_Homo sapiens_hsa030600.29173633
105Non-small cell lung cancer_Homo sapiens_hsa052230.28040439
106Adipocytokine signaling pathway_Homo sapiens_hsa049200.27658083
107Pentose and glucuronate interconversions_Homo sapiens_hsa000400.26033427
108HTLV-I infection_Homo sapiens_hsa051660.24944604
109Oxidative phosphorylation_Homo sapiens_hsa001900.24758609
110Focal adhesion_Homo sapiens_hsa045100.24573923
111Small cell lung cancer_Homo sapiens_hsa052220.23603977
112Alzheimers disease_Homo sapiens_hsa050100.23400167
113Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.22907115
114FoxO signaling pathway_Homo sapiens_hsa040680.21619106
115Prostate cancer_Homo sapiens_hsa052150.21474324
116Bladder cancer_Homo sapiens_hsa052190.21007972
117Nucleotide excision repair_Homo sapiens_hsa034200.20828475
118Melanoma_Homo sapiens_hsa052180.20046344
119Colorectal cancer_Homo sapiens_hsa052100.19736539
120Renin-angiotensin system_Homo sapiens_hsa046140.19491839
121Adherens junction_Homo sapiens_hsa045200.18465800
122Purine metabolism_Homo sapiens_hsa002300.17198408
123Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.16820015
124Huntingtons disease_Homo sapiens_hsa050160.15720293
125Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.14275518
126Non-homologous end-joining_Homo sapiens_hsa034500.13352284

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