CCDC112

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)6.53116066
2nucleobase catabolic process (GO:0046113)5.22509664
3neuron cell-cell adhesion (GO:0007158)4.64529554
4establishment of mitochondrion localization (GO:0051654)4.23446142
5postsynaptic membrane organization (GO:0001941)4.05591986
6neuron recognition (GO:0008038)4.05550313
7vocalization behavior (GO:0071625)3.87032198
8ionotropic glutamate receptor signaling pathway (GO:0035235)3.85784996
9regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.83596025
10glutamate receptor signaling pathway (GO:0007215)3.80444430
11presynaptic membrane assembly (GO:0097105)3.78415231
12behavioral response to nicotine (GO:0035095)3.69644342
13protein localization to synapse (GO:0035418)3.57009765
14dendritic spine morphogenesis (GO:0060997)3.44800328
15positive regulation of response to oxidative stress (GO:1902884)3.42653763
16positive regulation of cellular response to oxidative stress (GO:1900409)3.42653763
17positive regulation of dendritic spine morphogenesis (GO:0061003)3.42222646
18axonal fasciculation (GO:0007413)3.42121366
19establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.40633709
20mitochondrion transport along microtubule (GO:0047497)3.40633709
21positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.40166382
22intraciliary transport (GO:0042073)3.39726036
23neuron remodeling (GO:0016322)3.39032935
24presynaptic membrane organization (GO:0097090)3.34984142
25sequestering of actin monomers (GO:0042989)3.34331763
26neurotransmitter-gated ion channel clustering (GO:0072578)3.30229485
27cochlea development (GO:0090102)3.25326710
28layer formation in cerebral cortex (GO:0021819)3.23464222
29gamma-aminobutyric acid transport (GO:0015812)3.23125411
30regulation of glutamate receptor signaling pathway (GO:1900449)3.21870360
31gamma-aminobutyric acid signaling pathway (GO:0007214)3.19693522
32response to histamine (GO:0034776)3.18043870
33positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.14858807
34substrate-independent telencephalic tangential interneuron migration (GO:0021843)3.13225870
35substrate-independent telencephalic tangential migration (GO:0021826)3.13225870
36central nervous system projection neuron axonogenesis (GO:0021952)3.12322114
37dendrite development (GO:0016358)3.11859934
38neural tube formation (GO:0001841)3.10424295
39regulation of neuron projection regeneration (GO:0070570)3.08518490
40regulation of axon regeneration (GO:0048679)3.08518490
41retinal ganglion cell axon guidance (GO:0031290)3.08234523
42positive regulation of mitochondrial fission (GO:0090141)3.07024505
43kidney mesenchyme development (GO:0072074)3.04822220
44olfactory bulb development (GO:0021772)3.04120147
45neurofilament cytoskeleton organization (GO:0060052)3.01957391
46regulation of dendritic spine morphogenesis (GO:0061001)2.94112907
47cell migration in hindbrain (GO:0021535)2.91233264
48G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.89950144
49cerebral cortex radially oriented cell migration (GO:0021799)2.89185381
50positive regulation of synapse assembly (GO:0051965)2.88482101
51positive regulation of dendritic spine development (GO:0060999)2.88125659
52inner ear receptor cell development (GO:0060119)2.83866218
53DNA damage response, detection of DNA damage (GO:0042769)2.82731689
54regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.81989240
55regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.80375752
56protein polyglutamylation (GO:0018095)2.78906485
57neuron-neuron synaptic transmission (GO:0007270)2.77399821
58forebrain neuron differentiation (GO:0021879)2.76752304
59synaptic transmission, glutamatergic (GO:0035249)2.76416381
60establishment of integrated proviral latency (GO:0075713)2.75521714
61auditory behavior (GO:0031223)2.74504139
62regulation of long-term neuronal synaptic plasticity (GO:0048169)2.74472457
63axon extension (GO:0048675)2.74320747
64mRNA splice site selection (GO:0006376)2.72760808
65G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.72706372
66establishment of protein localization to mitochondrial membrane (GO:0090151)2.71126521
67transmission of nerve impulse (GO:0019226)2.70856743
68ribonucleoprotein complex disassembly (GO:0032988)2.70652210
69synaptic vesicle exocytosis (GO:0016079)2.69653263
70regulation of dendritic spine development (GO:0060998)2.69353833
71righting reflex (GO:0060013)2.69215148
72mechanosensory behavior (GO:0007638)2.69012024
73regulation of short-term neuronal synaptic plasticity (GO:0048172)2.68958345
74mitochondrial respiratory chain complex I assembly (GO:0032981)2.68834036
75NADH dehydrogenase complex assembly (GO:0010257)2.68834036
76mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.68834036
77positive regulation of synapse maturation (GO:0090129)2.68369582
78mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.68363966
79behavioral fear response (GO:0001662)2.66064965
80behavioral defense response (GO:0002209)2.66064965
81DNA double-strand break processing (GO:0000729)2.65926036
82regulation of synapse structural plasticity (GO:0051823)2.65303509
83negative regulation of peptidyl-threonine phosphorylation (GO:0010801)2.64884071
84spinal cord development (GO:0021510)2.64840497
85mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.64789150
86negative regulation of transcription regulatory region DNA binding (GO:2000678)2.64581943
87regulation of synapse maturation (GO:0090128)2.63886797
88exploration behavior (GO:0035640)2.63734941
89organelle disassembly (GO:1903008)2.63490209
90calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.63199782
91limb bud formation (GO:0060174)2.62267878
92adult walking behavior (GO:0007628)2.61002009
93fear response (GO:0042596)2.60440460
94regulation of excitatory postsynaptic membrane potential (GO:0060079)2.60375193
95regulation of collateral sprouting (GO:0048670)2.59920001
96head development (GO:0060322)2.59300737
97regulation of vesicle fusion (GO:0031338)2.58287210
98positive regulation of microtubule polymerization or depolymerization (GO:0031112)2.57490576
99cerebral cortex cell migration (GO:0021795)2.57026083
100innervation (GO:0060384)2.56681774
101neuronal action potential propagation (GO:0019227)2.55656530
102startle response (GO:0001964)2.55211649
103protein localization to cilium (GO:0061512)2.54434912
104regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315)2.54208633
105regulation of cilium movement (GO:0003352)2.53155755
106regulation of pigment cell differentiation (GO:0050932)2.52598408
107negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.52424693
108regulation of postsynaptic membrane potential (GO:0060078)2.51694008
109dendritic spine organization (GO:0097061)2.51584369
110regulation of synapse assembly (GO:0051963)2.51545261
111epithelial cell differentiation involved in kidney development (GO:0035850)2.51436374
112spinal cord association neuron differentiation (GO:0021527)2.51276575
113regulation of synapse organization (GO:0050807)2.50945504
114regulation of dopamine metabolic process (GO:0042053)2.50181912
115regulation of catecholamine metabolic process (GO:0042069)2.50181912
116regulation of respiratory system process (GO:0044065)2.49682151
117hindbrain development (GO:0030902)2.49588767
118negative regulation of synaptic transmission, GABAergic (GO:0032229)2.48872032
119protein complex biogenesis (GO:0070271)2.48592737
120cilium morphogenesis (GO:0060271)2.48230336
121epithelial cilium movement (GO:0003351)2.48074548
122protein neddylation (GO:0045116)2.47750865
123ribosomal small subunit biogenesis (GO:0042274)2.47693239
124central nervous system neuron axonogenesis (GO:0021955)2.46571851
125resolution of meiotic recombination intermediates (GO:0000712)2.45204735
126sympathetic nervous system development (GO:0048485)2.44403597
127regulation of neuronal synaptic plasticity (GO:0048168)2.44297765
128behavioral response to ethanol (GO:0048149)2.43968546
129neuron migration (GO:0001764)2.42796537
130cytoskeleton-dependent intracellular transport (GO:0030705)2.42654537
131short-term memory (GO:0007614)2.42414124
132negative regulation of dendrite development (GO:2000171)2.42285061
133long-term synaptic potentiation (GO:0060291)2.42016200
134establishment of melanosome localization (GO:0032401)2.41311143
135ephrin receptor signaling pathway (GO:0048013)2.41174824
136regulation of telomere maintenance (GO:0032204)2.41094555
137positive regulation of membrane potential (GO:0045838)2.40591954
138metanephric mesenchyme development (GO:0072075)2.40139963
139energy coupled proton transport, down electrochemical gradient (GO:0015985)2.39245818
140ATP synthesis coupled proton transport (GO:0015986)2.39245818
141long-term memory (GO:0007616)2.38757380
142cell proliferation in forebrain (GO:0021846)2.38413055
143regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.38151755
144regulation of mitotic spindle checkpoint (GO:1903504)2.38151755
145regulation of respiratory gaseous exchange (GO:0043576)2.37691515
146nonmotile primary cilium assembly (GO:0035058)2.37326263
147GTP biosynthetic process (GO:0006183)2.35059820
148synaptic vesicle endocytosis (GO:0048488)2.35058319
149dendrite morphogenesis (GO:0048813)2.35049567
150synapse assembly (GO:0007416)2.34811640
151cilium organization (GO:0044782)2.34534688
152synapse organization (GO:0050808)2.34237911
153regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.34210942
154regulation of development, heterochronic (GO:0040034)2.33837107
155negative regulation of neurotransmitter transport (GO:0051589)2.32701813
156Rac protein signal transduction (GO:0016601)2.31522780
157regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.30791115
158SMAD protein complex assembly (GO:0007183)2.29488206
159hippocampus development (GO:0021766)2.29426431
160positive regulation of neurotransmitter secretion (GO:0001956)2.29359220
161opioid receptor signaling pathway (GO:0038003)2.28985560
162negative regulation of microtubule polymerization (GO:0031115)2.28562065
163learning (GO:0007612)2.27812597
164peptidyl-arginine omega-N-methylation (GO:0035247)2.26634316
165positive regulation of meiosis (GO:0045836)2.26460674
166maturation of SSU-rRNA (GO:0030490)2.26346422

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.13008495
2GBX2_23144817_ChIP-Seq_PC3_Human3.65696498
3JARID2_20064375_ChIP-Seq_MESCs_Mouse3.02861548
4RBPJ_22232070_ChIP-Seq_NCS_Mouse2.71620155
5FUS_26573619_Chip-Seq_HEK293_Human2.68784717
6EZH2_27304074_Chip-Seq_ESCs_Mouse2.67363036
7TAF15_26573619_Chip-Seq_HEK293_Human2.52739484
8SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.51795367
9BMI1_23680149_ChIP-Seq_NPCS_Mouse2.51319360
10SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.41645732
11SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.27863415
12CBX2_27304074_Chip-Seq_ESCs_Mouse2.27089496
13EZH2_18974828_ChIP-Seq_MESCs_Mouse2.24272264
14RNF2_18974828_ChIP-Seq_MESCs_Mouse2.24272264
15CTBP2_25329375_ChIP-Seq_LNCAP_Human2.21396452
16EED_16625203_ChIP-ChIP_MESCs_Mouse2.17526662
17IGF1R_20145208_ChIP-Seq_DFB_Human2.17311776
18JARID2_20075857_ChIP-Seq_MESCs_Mouse2.15810731
19RNF2_27304074_Chip-Seq_NSC_Mouse2.15222569
20ZFP57_27257070_Chip-Seq_ESCs_Mouse2.14712909
21CTBP1_25329375_ChIP-Seq_LNCAP_Human2.14498617
22SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.09212473
23ZNF274_21170338_ChIP-Seq_K562_Hela2.05291039
24SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.03259237
25* POU3F2_20337985_ChIP-ChIP_501MEL_Human2.02022181
26HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.95578458
27RNF2_27304074_Chip-Seq_ESCs_Mouse1.94399237
28GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.89545133
29HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.84629719
30* P300_19829295_ChIP-Seq_ESCs_Human1.77613089
31* EWS_26573619_Chip-Seq_HEK293_Human1.72618344
32REST_21632747_ChIP-Seq_MESCs_Mouse1.72418676
33PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.71965003
34MTF2_20144788_ChIP-Seq_MESCs_Mouse1.69336408
35EZH2_27294783_Chip-Seq_ESCs_Mouse1.68602945
36GABP_17652178_ChIP-ChIP_JURKAT_Human1.67085987
37POU5F1_16153702_ChIP-ChIP_HESCs_Human1.66562788
38CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.66535465
39SMAD3_21741376_ChIP-Seq_EPCs_Human1.63754371
40TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.63325188
41NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.61523487
42SUZ12_27294783_Chip-Seq_ESCs_Mouse1.60587592
43AR_21572438_ChIP-Seq_LNCaP_Human1.59428050
44PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.59076490
45SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.58622176
46ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.58592396
47GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.58206164
48VDR_22108803_ChIP-Seq_LS180_Human1.56536499
49RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.53842961
50* SMAD4_21799915_ChIP-Seq_A2780_Human1.53057599
51* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.47872851
52RING1B_27294783_Chip-Seq_NPCs_Mouse1.45179123
53IKZF1_21737484_ChIP-ChIP_HCT116_Human1.42991952
54KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.41370201
55RARB_27405468_Chip-Seq_BRAIN_Mouse1.40911739
56SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.39493129
57EST1_17652178_ChIP-ChIP_JURKAT_Human1.37354344
58OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.35936827
59SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.34980786
60MYC_18940864_ChIP-ChIP_HL60_Human1.34170137
61TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.33744501
62PIAS1_25552417_ChIP-Seq_VCAP_Human1.28267313
63CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.27493744
64GATA1_26923725_Chip-Seq_HPCs_Mouse1.27300024
65ER_23166858_ChIP-Seq_MCF-7_Human1.25603691
66TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.23799142
67RING1B_27294783_Chip-Seq_ESCs_Mouse1.23764748
68POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.22878191
69TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.22878191
70* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.22171494
71P53_22127205_ChIP-Seq_FIBROBLAST_Human1.21871378
72E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.21281300
73NANOG_18555785_Chip-Seq_ESCs_Mouse1.21167698
74IRF1_19129219_ChIP-ChIP_H3396_Human1.20829285
75SALL1_21062744_ChIP-ChIP_HESCs_Human1.20287706
76FLI1_27457419_Chip-Seq_LIVER_Mouse1.19603729
77CBP_20019798_ChIP-Seq_JUKART_Human1.19328995
78IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.19328995
79KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.17648661
80KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.17648661
81KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.17648661
82AR_25329375_ChIP-Seq_VCAP_Human1.16525256
83KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.16040436
84REST_18959480_ChIP-ChIP_MESCs_Mouse1.15963633
85WT1_19549856_ChIP-ChIP_CCG9911_Human1.15343058
86ELK1_19687146_ChIP-ChIP_HELA_Human1.14468974
87RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.12498327
88TP63_19390658_ChIP-ChIP_HaCaT_Human1.12017487
89AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.11423781
90GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.09770741
91TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.09525081
92JUN_21703547_ChIP-Seq_K562_Human1.09485244
93HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.09455820
94* KLF5_20875108_ChIP-Seq_MESCs_Mouse1.07114272
95E2F1_18555785_Chip-Seq_ESCs_Mouse1.06345995
96* STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.06054159
97SOX2_21211035_ChIP-Seq_LN229_Gbm1.05668880
98BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.05657766
99* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.05373002
100MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.05203248
101SOX9_26525672_Chip-Seq_HEART_Mouse1.05189575
102TP53_18474530_ChIP-ChIP_U2OS_Human1.04963692
103CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04782396
104PCGF2_27294783_Chip-Seq_ESCs_Mouse1.04604854
105SOX2_16153702_ChIP-ChIP_HESCs_Human1.03533200
106ARNT_22903824_ChIP-Seq_MCF-7_Human1.03382885
107STAT3_23295773_ChIP-Seq_U87_Human1.03303182
108EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.02470658
109ETS1_20019798_ChIP-Seq_JURKAT_Human1.01834449
110RUNX2_22187159_ChIP-Seq_PCA_Human1.01644207
111TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00674707
112TAL1_26923725_Chip-Seq_HPCs_Mouse1.00052123
113BCAT_22108803_ChIP-Seq_LS180_Human0.99756975
114TP53_22573176_ChIP-Seq_HFKS_Human0.99119053
115CMYC_18555785_Chip-Seq_ESCs_Mouse0.98661981
116TP53_20018659_ChIP-ChIP_R1E_Mouse0.98629140
117ERG_21242973_ChIP-ChIP_JURKAT_Human0.98450592
118FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.97581408
119* TCF4_23295773_ChIP-Seq_U87_Human0.97014321
120MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.96948562
121MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.96717829
122NR3C1_21868756_ChIP-Seq_MCF10A_Human0.92942595
123RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.92936389
124NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.92138097
125REST_19997604_ChIP-ChIP_NEURONS_Mouse0.92052718

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.78236285
2MP0004859_abnormal_synaptic_plasticity3.55312469
3MP0004270_analgesia2.99526643
4MP0003635_abnormal_synaptic_transmissio2.84915324
5MP0009379_abnormal_foot_pigmentation2.63270752
6MP0000778_abnormal_nervous_system2.62561978
7MP0002063_abnormal_learning/memory/cond2.51117451
8MP0006292_abnormal_olfactory_placode2.46587035
9MP0001188_hyperpigmentation2.43481351
10MP0003787_abnormal_imprinting2.39457670
11MP0001968_abnormal_touch/_nociception2.36826818
12MP0009745_abnormal_behavioral_response2.29066835
13MP0005423_abnormal_somatic_nervous2.25636814
14MP0002572_abnormal_emotion/affect_behav2.13510840
15MP0002102_abnormal_ear_morphology2.10502720
16MP0002822_catalepsy2.09678313
17MP0002736_abnormal_nociception_after1.92978490
18MP0001486_abnormal_startle_reflex1.89965983
19MP0006276_abnormal_autonomic_nervous1.89357053
20MP0002734_abnormal_mechanical_nocicepti1.86354793
21MP0000569_abnormal_digit_pigmentation1.86070740
22MP0005409_darkened_coat_color1.83858432
23MP0002184_abnormal_innervation1.81642407
24MP0002064_seizures1.80653613
25MP0003121_genomic_imprinting1.73461742
26MP0001529_abnormal_vocalization1.73360502
27MP0001905_abnormal_dopamine_level1.73146594
28MP0003122_maternal_imprinting1.70103071
29MP0002272_abnormal_nervous_system1.66979274
30MP0003123_paternal_imprinting1.65729350
31MP0003938_abnormal_ear_development1.61425256
32MP0002653_abnormal_ependyma_morphology1.56964002
33MP0002067_abnormal_sensory_capabilities1.56545199
34MP0000631_abnormal_neuroendocrine_gland1.55085937
35MP0002735_abnormal_chemical_nociception1.54245713
36MP0001501_abnormal_sleep_pattern1.51553679
37MP0002557_abnormal_social/conspecific_i1.48542162
38MP0002234_abnormal_pharynx_morphology1.46553960
39MP0005551_abnormal_eye_electrophysiolog1.43749426
40MP0002733_abnormal_thermal_nociception1.42774705
41MP0002638_abnormal_pupillary_reflex1.42166918
42MP0001440_abnormal_grooming_behavior1.41208748
43MP0000049_abnormal_middle_ear1.35811237
44MP0005386_behavior/neurological_phenoty1.34267826
45MP0004924_abnormal_behavior1.34267826
46MP0000955_abnormal_spinal_cord1.33464511
47MP0005645_abnormal_hypothalamus_physiol1.32223786
48MP0008877_abnormal_DNA_methylation1.30623823
49MP0003890_abnormal_embryonic-extraembry1.30447339
50MP0003937_abnormal_limbs/digits/tail_de1.30080601
51MP0003861_abnormal_nervous_system1.29572188
52MP0002152_abnormal_brain_morphology1.28467848
53MP0008058_abnormal_DNA_repair1.27871374
54MP0001293_anophthalmia1.25324661
55MP0004145_abnormal_muscle_electrophysio1.23013117
56MP0002882_abnormal_neuron_morphology1.22770364
57MP0001970_abnormal_pain_threshold1.19094735
58MP0006072_abnormal_retinal_apoptosis1.17220169
59MP0004742_abnormal_vestibular_system1.16896398
60MP0000026_abnormal_inner_ear1.16678414
61MP0004811_abnormal_neuron_physiology1.14460049
62MP0005253_abnormal_eye_physiology1.11361173
63MP0003385_abnormal_body_wall1.10705929
64MP0001963_abnormal_hearing_physiology1.10540442
65MP0003119_abnormal_digestive_system1.08280960
66MP0005499_abnormal_olfactory_system1.07824457
67MP0005394_taste/olfaction_phenotype1.07824457
68MP0009046_muscle_twitch1.07409356
69MP0005195_abnormal_posterior_eye1.05395302
70MP0003942_abnormal_urinary_system1.03530001
71MP0008995_early_reproductive_senescence1.03411608
72MP0002752_abnormal_somatic_nervous1.03099858
73MP0002249_abnormal_larynx_morphology1.02936792
74MP0002938_white_spotting1.02376934
75MP0001348_abnormal_lacrimal_gland1.00019067
76MP0001485_abnormal_pinna_reflex0.99208259
77MP0009250_abnormal_appendicular_skeleto0.99168946
78MP0002066_abnormal_motor_capabilities/c0.97717181
79MP0003755_abnormal_palate_morphology0.97598057
80MP0003136_yellow_coat_color0.95174891
81MP0004133_heterotaxia0.94908907
82MP0004885_abnormal_endolymph0.94766993
83MP0005367_renal/urinary_system_phenotyp0.93267805
84MP0000516_abnormal_urinary_system0.93267805
85MP0001986_abnormal_taste_sensitivity0.93090408
86MP0004142_abnormal_muscle_tone0.92238261
87MP0002233_abnormal_nose_morphology0.91437575
88MP0005646_abnormal_pituitary_gland0.90714405
89MP0003315_abnormal_perineum_morphology0.90273076
90MP0002210_abnormal_sex_determination0.89105939
91MP0002751_abnormal_autonomic_nervous0.87787291
92MP0002081_perinatal_lethality0.86880419
93MP0000534_abnormal_ureter_morphology0.86225969
94MP0008789_abnormal_olfactory_epithelium0.86084035
95MP0001984_abnormal_olfaction0.84617694
96MP0000566_synostosis0.84606910
97MP0005174_abnormal_tail_pigmentation0.84553727
98MP0000647_abnormal_sebaceous_gland0.84434827
99MP0003698_abnormal_male_reproductive0.84083394
100MP0002909_abnormal_adrenal_gland0.82578033
101MP0003011_delayed_dark_adaptation0.81784281
102MP0002160_abnormal_reproductive_system0.80842679
103MP0002069_abnormal_eating/drinking_beha0.80453976
104MP0000537_abnormal_urethra_morphology0.80238394
105MP0002837_dystrophic_cardiac_calcinosis0.80094237
106MP0005391_vision/eye_phenotype0.79990643
107MP0001502_abnormal_circadian_rhythm0.79427324
108MP0002116_abnormal_craniofacial_bone0.78761198
109MP0003718_maternal_effect0.78428105
110MP0002177_abnormal_outer_ear0.78365921
111MP0005084_abnormal_gallbladder_morpholo0.77380566
112MP0002229_neurodegeneration0.77203723
113MP0001286_abnormal_eye_development0.75450391
114MP0002114_abnormal_axial_skeleton0.75244631
115MP0001943_abnormal_respiration0.74219805
116MP0001324_abnormal_eye_pigmentation0.73027552
117MP0005187_abnormal_penis_morphology0.71073470
118MP0003935_abnormal_craniofacial_develop0.71056612
119MP0003567_abnormal_fetal_cardiomyocyte0.70528328
120MP0005379_endocrine/exocrine_gland_phen0.69452108
121MP0002282_abnormal_trachea_morphology0.66206739
122MP0003941_abnormal_skin_development0.65996915
123MP0002932_abnormal_joint_morphology0.65819996

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)4.20602364
2Supernumerary spleens (HP:0009799)3.23891669
3Focal seizures (HP:0007359)3.23192355
4Cortical dysplasia (HP:0002539)3.21874939
5Lissencephaly (HP:0001339)3.10102290
6Atonic seizures (HP:0010819)3.06199947
7Febrile seizures (HP:0002373)2.99455021
8Acute necrotizing encephalopathy (HP:0006965)2.86152935
9Retinal dysplasia (HP:0007973)2.85909587
10Epileptic encephalopathy (HP:0200134)2.78624539
11Protruding tongue (HP:0010808)2.78091585
12Polyphagia (HP:0002591)2.77489206
13Visual hallucinations (HP:0002367)2.77249555
14Pancreatic cysts (HP:0001737)2.76030283
15Gait imbalance (HP:0002141)2.72593204
16Broad-based gait (HP:0002136)2.70572823
17Myokymia (HP:0002411)2.69151378
18Amblyopia (HP:0000646)2.67172082
19Progressive inability to walk (HP:0002505)2.58698129
20Medial flaring of the eyebrow (HP:0010747)2.55923631
21Hyperventilation (HP:0002883)2.55834438
22Dynein arm defect of respiratory motile cilia (HP:0012255)2.50852875
23Absent/shortened dynein arms (HP:0200106)2.50852875
24Acute encephalopathy (HP:0006846)2.48574906
25Abnormal mitochondria in muscle tissue (HP:0008316)2.46610199
26Progressive macrocephaly (HP:0004481)2.46159433
27Abnormality of the renal medulla (HP:0100957)2.45097378
28Pachygyria (HP:0001302)2.43657649
29Cerebral inclusion bodies (HP:0100314)2.41205457
30Inappropriate behavior (HP:0000719)2.40767545
31Volvulus (HP:0002580)2.40619552
32Aplasia/Hypoplasia of the brainstem (HP:0007362)2.37537826
33Hypoplasia of the brainstem (HP:0002365)2.37537826
34Congenital primary aphakia (HP:0007707)2.35914186
35Failure to thrive in infancy (HP:0001531)2.33832102
36Excessive salivation (HP:0003781)2.32856747
37Drooling (HP:0002307)2.32856747
38Absence seizures (HP:0002121)2.28875563
39Type II lissencephaly (HP:0007260)2.24171143
40Hypothermia (HP:0002045)2.24028165
41Amyotrophic lateral sclerosis (HP:0007354)2.22601069
42Hydroureter (HP:0000072)2.19228834
43Abnormal respiratory motile cilium morphology (HP:0005938)2.18056683
44Abnormal respiratory epithelium morphology (HP:0012253)2.18056683
45Abnormal ciliary motility (HP:0012262)2.16094857
46Nephrogenic diabetes insipidus (HP:0009806)2.16035375
47Oligodactyly (hands) (HP:0001180)2.14585934
48Congenital stationary night blindness (HP:0007642)2.12397140
49Genital tract atresia (HP:0001827)2.12075667
50Dialeptic seizures (HP:0011146)2.11689257
51Agitation (HP:0000713)2.10896962
52Mitochondrial inheritance (HP:0001427)2.08789713
53Chronic hepatic failure (HP:0100626)2.08764184
54Abnormal hair whorl (HP:0010721)2.08648371
55Abnormality of the phalanges of the 2nd finger (HP:0009541)2.07567848
56Absent speech (HP:0001344)2.07193868
57Facial hemangioma (HP:0000329)2.05654065
58Sclerocornea (HP:0000647)2.04920899
59Impaired vibration sensation in the lower limbs (HP:0002166)2.02429743
60Inability to walk (HP:0002540)2.02223977
61True hermaphroditism (HP:0010459)2.02111026
62Vaginal atresia (HP:0000148)2.02002064
63Increased CSF lactate (HP:0002490)2.00388195
64Stereotypic behavior (HP:0000733)2.00378294
65Urinary urgency (HP:0000012)2.00229920
66Aplasia/Hypoplasia of the lens (HP:0008063)1.99249614
67Specific learning disability (HP:0001328)1.98916985
68Neurofibrillary tangles (HP:0002185)1.97222612
69Progressive cerebellar ataxia (HP:0002073)1.96354777
70Limb dystonia (HP:0002451)1.93713701
71Asplenia (HP:0001746)1.93709317
72Pancreatic fibrosis (HP:0100732)1.93117670
7311 pairs of ribs (HP:0000878)1.93007350
74Morphological abnormality of the middle ear (HP:0008609)1.90556369
75Hyperglycinemia (HP:0002154)1.89423954
76Anophthalmia (HP:0000528)1.89296990
77Hypsarrhythmia (HP:0002521)1.89288680
78Esotropia (HP:0000565)1.89243546
79Poor suck (HP:0002033)1.88650053
80Postaxial foot polydactyly (HP:0001830)1.86931597
81Spastic tetraplegia (HP:0002510)1.86908028
82Hemiparesis (HP:0001269)1.86305756
83Patellar aplasia (HP:0006443)1.86243130
84Reticulocytopenia (HP:0001896)1.85208530
85Gastroesophageal reflux (HP:0002020)1.84873366
86Abnormal respiratory motile cilium physiology (HP:0012261)1.84849858
87Apathy (HP:0000741)1.84649071
88Micropenis (HP:0000054)1.84134208
89Broad foot (HP:0001769)1.83416181
90Hepatocellular necrosis (HP:0001404)1.83275484
91Action tremor (HP:0002345)1.83117569
92Abnormality of midbrain morphology (HP:0002418)1.82527392
93Molar tooth sign on MRI (HP:0002419)1.82527392
94Abnormality of the labia minora (HP:0012880)1.82515386
95Exotropia (HP:0000577)1.82113976
96Epileptiform EEG discharges (HP:0011182)1.81301059
97EEG with generalized epileptiform discharges (HP:0011198)1.79688048
98Optic nerve hypoplasia (HP:0000609)1.79054486
99Heterochromia iridis (HP:0001100)1.78531025
100Atelectasis (HP:0100750)1.78409842
101Cystic liver disease (HP:0006706)1.78356072
102Stenosis of the external auditory canal (HP:0000402)1.77821010
103Cerebral edema (HP:0002181)1.77422850
104Aplasia/Hypoplasia of the tongue (HP:0010295)1.76898627
105Aplasia/Hypoplasia of the patella (HP:0006498)1.76533461
106Aplasia/Hypoplasia of the sternum (HP:0006714)1.76527543
107Scanning speech (HP:0002168)1.73664911
108Aplasia/Hypoplasia of the spleen (HP:0010451)1.73637874
109Pendular nystagmus (HP:0012043)1.72977307
110Cutaneous finger syndactyly (HP:0010554)1.72686566
111Lipid accumulation in hepatocytes (HP:0006561)1.71733461
112Generalized tonic-clonic seizures (HP:0002069)1.71075406
113Poor eye contact (HP:0000817)1.70752477
114Aganglionic megacolon (HP:0002251)1.70238354
115Metaphyseal dysplasia (HP:0100255)1.69831340
116Decreased testicular size (HP:0008734)1.69508898
117Increased hepatocellular lipid droplets (HP:0006565)1.68420437
118Cupped ear (HP:0000378)1.67841878
119Tubulointerstitial nephritis (HP:0001970)1.67490108
120Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.66904209
121Muscular hypotonia of the trunk (HP:0008936)1.66849980
122Intellectual disability, severe (HP:0010864)1.66314641
123Scrotal hypoplasia (HP:0000046)1.66231146
124Septo-optic dysplasia (HP:0100842)1.66168208
125Macroglossia (HP:0000158)1.65142668
126Genetic anticipation (HP:0003743)1.64780798
127Nephronophthisis (HP:0000090)1.64273298
128Abnormality of salivation (HP:0100755)1.63676625
129Bifid tongue (HP:0010297)1.63268969
130Supranuclear gaze palsy (HP:0000605)1.63138607
131Mutism (HP:0002300)1.62634090
132Small hand (HP:0200055)1.61679208
133Hepatoblastoma (HP:0002884)1.61382111
134Colon cancer (HP:0003003)1.61044048
135Postaxial hand polydactyly (HP:0001162)1.61031578
136Abnormality of the phalanges of the hallux (HP:0010057)1.59715960
137Abnormality of the corticospinal tract (HP:0002492)1.58998629
138Preaxial hand polydactyly (HP:0001177)1.58527771
139Degeneration of the lateral corticospinal tracts (HP:0002314)1.58351221
140Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.58351221
141Anencephaly (HP:0002323)1.57570794
142Diminished motivation (HP:0000745)1.56880266
143Absent frontal sinuses (HP:0002688)1.56474299
144Autism (HP:0000717)1.54807272
145Short foot (HP:0001773)1.53056346
146Buphthalmos (HP:0000557)1.52600548
147Widely spaced teeth (HP:0000687)1.52155844
148Fair hair (HP:0002286)1.51632685
149Insidious onset (HP:0003587)1.49633966
150Termporal pattern (HP:0011008)1.49633966
151Poor coordination (HP:0002370)1.48755515
152Renal hypoplasia (HP:0000089)1.48029607
153Narrow forehead (HP:0000341)1.47289689
154Gaze-evoked nystagmus (HP:0000640)1.46434975
155Annular pancreas (HP:0001734)1.45958158

Predicted kinase interactions (KEA)

RankGene SetZ-score
1RIPK43.72141896
2NTRK33.62672779
3CASK3.35649198
4PNCK3.22111136
5MARK13.12544132
6TRIM282.91111388
7EPHA42.83847566
8MAP3K42.43904128
9MAP3K92.43043169
10MAP2K72.41613791
11MKNK12.14588775
12PLK22.11130235
13SIK22.08115421
14BMPR22.04701675
15MAPK131.96747573
16MKNK21.94563025
17TNIK1.72370140
18MAP3K121.71010546
19PINK11.69796629
20GRK51.64111325
21ERBB31.62061283
22GRK71.53455750
23KSR11.50526611
24MAP4K21.49666103
25WNK41.47823395
26MINK11.47705635
27FGR1.43934163
28NME11.43267393
29SRPK11.39895216
30DYRK1A1.33690226
31NTRK21.28847750
32FRK1.22563760
33FES1.21733661
34DYRK21.21716534
35CDC71.20549588
36UHMK11.18475357
37STK161.16321056
38BCR1.16194697
39GRK11.14380249
40NUAK11.13829648
41ARAF1.12899380
42CSNK1G31.12660841
43RPS6KA41.12396349
44CSNK1G21.11652596
45CSNK1A1L1.07158092
46MAPKAPK51.03004920
47CAMK2B1.02890202
48CDK191.00967147
49MAP2K41.00661988
50CAMK1G0.96069422
51CDK50.94207656
52BMPR1B0.92337651
53KSR20.91941973
54CAMK2A0.91841714
55MAP3K60.91402886
56PLK30.91269043
57RAF10.88100308
58SIK30.86828906
59NEK10.86746799
60BCKDK0.86044991
61PRKCG0.83309803
62ZAK0.82035604
63DYRK1B0.79468480
64YES10.77338847
65WNK30.73641991
66TLK10.73559527
67PTK2B0.72379438
68RPS6KA20.72128662
69CSNK1G10.71942584
70DAPK10.71667126
71DYRK30.71264365
72ADRBK20.70957993
73LATS20.70376934
74SGK2230.70111490
75SGK4940.70111490
76DAPK20.70077149
77EPHA30.69258270
78PKN10.67014652
79PLK10.66003235
80CCNB10.65257502
81LIMK10.65159903
82ADRBK10.64696273
83PAK60.62531495
84ACVR1B0.62507226
85TYRO30.61798232
86MOS0.61320935
87PRKCE0.61165972
88SGK20.59402905
89NTRK10.59274877
90CSNK1E0.59173587
91PRKCZ0.58749619
92PLK40.57007458
93MAP3K20.56985703
94MUSK0.55847990
95STK110.55164157
96EPHB20.54071912
97CAMKK20.52327460
98NEK20.52315458
99BRD40.51638455
100RPS6KA50.50527127
101CDK30.50507835
102VRK10.49998322
103PRKACB0.48300591
104CDK80.48297787
105STK390.46832493
106CDK140.46686245
107CAMK40.46598690
108INSRR0.45128529
109CAMK1D0.44471552
110CDK180.44376603
111LATS10.44150359
112STK38L0.43985383
113PRKACA0.42715719
114CDK11A0.41225134
115ATR0.40497341
116ATM0.40010281
117OXSR10.39980963
118WEE10.39675797
119CDK150.39598005
120TSSK60.39440218
121FER0.39173749
122PIK3CA0.39121367
123MAPK100.38137877
124SGK10.37801116
125CAMK2D0.37443969
126CAMK10.37131625
127PAK30.36994463
128BRAF0.36926463
129ROCK20.36801826
130MAPK90.35503444
131PHKG20.35487323
132PHKG10.35487323
133DMPK0.35221648
134CSNK1A10.34764861
135PRKCI0.33431298
136CSNK1D0.32995373
137PRKD30.32920809
138CSNK2A20.32666489
139BLK0.32635131
140PRKG10.31850337
141MAP3K130.30637572
142PRKDC0.30495502

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.48154399
2Long-term potentiation_Homo sapiens_hsa047202.47837348
3Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.46969277
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.42656090
5Glutamatergic synapse_Homo sapiens_hsa047242.30743742
6Circadian entrainment_Homo sapiens_hsa047132.25923476
7Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.25468633
8Taste transduction_Homo sapiens_hsa047422.20023522
9Amphetamine addiction_Homo sapiens_hsa050312.14532618
10Serotonergic synapse_Homo sapiens_hsa047262.10849600
11Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.07150076
12Morphine addiction_Homo sapiens_hsa050322.03737983
13Steroid biosynthesis_Homo sapiens_hsa001002.03555379
14Long-term depression_Homo sapiens_hsa047301.96911082
15GABAergic synapse_Homo sapiens_hsa047271.92805426
16Dopaminergic synapse_Homo sapiens_hsa047281.90510191
17Olfactory transduction_Homo sapiens_hsa047401.89860015
18Renin secretion_Homo sapiens_hsa049241.72939152
19Axon guidance_Homo sapiens_hsa043601.58587013
20Phototransduction_Homo sapiens_hsa047441.58437313
21Salivary secretion_Homo sapiens_hsa049701.55877458
22Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.51952532
23Ribosome_Homo sapiens_hsa030101.51676459
24Butanoate metabolism_Homo sapiens_hsa006501.47301249
25GnRH signaling pathway_Homo sapiens_hsa049121.44199470
26Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.43446847
27Cocaine addiction_Homo sapiens_hsa050301.38889725
28Oxytocin signaling pathway_Homo sapiens_hsa049211.38587060
29Cholinergic synapse_Homo sapiens_hsa047251.35834186
30Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.34249460
31Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.33741818
32Alzheimers disease_Homo sapiens_hsa050101.33719894
33Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.33715140
34Calcium signaling pathway_Homo sapiens_hsa040201.31088958
35Gap junction_Homo sapiens_hsa045401.31067543
36Synaptic vesicle cycle_Homo sapiens_hsa047211.27598937
37Propanoate metabolism_Homo sapiens_hsa006401.25696364
38Melanogenesis_Homo sapiens_hsa049161.21875868
39Oocyte meiosis_Homo sapiens_hsa041141.19621074
40Aldosterone synthesis and secretion_Homo sapiens_hsa049251.15981671
41Wnt signaling pathway_Homo sapiens_hsa043101.12099881
42Oxidative phosphorylation_Homo sapiens_hsa001901.09305653
43Insulin secretion_Homo sapiens_hsa049111.08704434
44Gastric acid secretion_Homo sapiens_hsa049711.08658789
45Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.06336454
46Estrogen signaling pathway_Homo sapiens_hsa049150.97399459
47Dorso-ventral axis formation_Homo sapiens_hsa043200.97278625
48Huntingtons disease_Homo sapiens_hsa050160.97113124
49Hedgehog signaling pathway_Homo sapiens_hsa043400.94654897
50cAMP signaling pathway_Homo sapiens_hsa040240.94268865
51Parkinsons disease_Homo sapiens_hsa050120.93705456
52Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.92497378
53ErbB signaling pathway_Homo sapiens_hsa040120.92426195
54mRNA surveillance pathway_Homo sapiens_hsa030150.92258651
55RNA polymerase_Homo sapiens_hsa030200.91590849
56Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.90129578
57Homologous recombination_Homo sapiens_hsa034400.89148986
58Collecting duct acid secretion_Homo sapiens_hsa049660.87164888
59Base excision repair_Homo sapiens_hsa034100.87141022
60Regulation of autophagy_Homo sapiens_hsa041400.86319523
61MAPK signaling pathway_Homo sapiens_hsa040100.85361695
62Selenocompound metabolism_Homo sapiens_hsa004500.84032347
63Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.82473971
64Vibrio cholerae infection_Homo sapiens_hsa051100.82388432
65Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.82037388
66Spliceosome_Homo sapiens_hsa030400.81757551
67Ras signaling pathway_Homo sapiens_hsa040140.81096988
68Choline metabolism in cancer_Homo sapiens_hsa052310.80511033
69cGMP-PKG signaling pathway_Homo sapiens_hsa040220.80029517
70Protein export_Homo sapiens_hsa030600.79434401
71Cardiac muscle contraction_Homo sapiens_hsa042600.79140968
72Phosphatidylinositol signaling system_Homo sapiens_hsa040700.78150270
73African trypanosomiasis_Homo sapiens_hsa051430.77878122
74Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.77565601
75Glioma_Homo sapiens_hsa052140.77146378
76Vascular smooth muscle contraction_Homo sapiens_hsa042700.76718356
77Alcoholism_Homo sapiens_hsa050340.76577016
78Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.74805128
79Basal cell carcinoma_Homo sapiens_hsa052170.74759446
80Linoleic acid metabolism_Homo sapiens_hsa005910.74719502
81Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.74701532
82Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.74021333
83Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.72411890
84Proteasome_Homo sapiens_hsa030500.71736846
85alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.68137387
86Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.65736452
87Ether lipid metabolism_Homo sapiens_hsa005650.65599442
88RNA degradation_Homo sapiens_hsa030180.65198362
89Pyruvate metabolism_Homo sapiens_hsa006200.65063451
90Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.64849778
91Fanconi anemia pathway_Homo sapiens_hsa034600.63808141
92Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.63737846
93Fatty acid elongation_Homo sapiens_hsa000620.63240642
94VEGF signaling pathway_Homo sapiens_hsa043700.63162843
95Renal cell carcinoma_Homo sapiens_hsa052110.61864833
96Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.61684155
97Phospholipase D signaling pathway_Homo sapiens_hsa040720.60399244
98Rap1 signaling pathway_Homo sapiens_hsa040150.60298518
99Sphingolipid signaling pathway_Homo sapiens_hsa040710.57473851
100Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.57105218
101Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.56938479
102Cell cycle_Homo sapiens_hsa041100.56388288
103Folate biosynthesis_Homo sapiens_hsa007900.56151836
104Colorectal cancer_Homo sapiens_hsa052100.55819945
105Purine metabolism_Homo sapiens_hsa002300.55455259
106Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.53283295
107Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.53101620
108Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.52327993
109Nitrogen metabolism_Homo sapiens_hsa009100.52029819
110Hippo signaling pathway_Homo sapiens_hsa043900.50771845
111Pyrimidine metabolism_Homo sapiens_hsa002400.50267229
112Non-homologous end-joining_Homo sapiens_hsa034500.49053256
113Transcriptional misregulation in cancer_Homo sapiens_hsa052020.48046286
114Ovarian steroidogenesis_Homo sapiens_hsa049130.47813232
115Metabolic pathways_Homo sapiens_hsa011000.46999769
116Pancreatic secretion_Homo sapiens_hsa049720.46966549
117Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.46173873
118RNA transport_Homo sapiens_hsa030130.45991510
119Peroxisome_Homo sapiens_hsa041460.45524388
120Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.45236258
121Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.44780394
122Neurotrophin signaling pathway_Homo sapiens_hsa047220.44455319
123Tryptophan metabolism_Homo sapiens_hsa003800.43298619
124Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.42286024
125TGF-beta signaling pathway_Homo sapiens_hsa043500.40920589
126Pathways in cancer_Homo sapiens_hsa052000.40599970
127Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.40380969
128SNARE interactions in vesicular transport_Homo sapiens_hsa041300.40216188
129Regulation of actin cytoskeleton_Homo sapiens_hsa048100.40169408
130Mismatch repair_Homo sapiens_hsa034300.38896679
131Nucleotide excision repair_Homo sapiens_hsa034200.38791488
132Cysteine and methionine metabolism_Homo sapiens_hsa002700.38695894
133Thyroid hormone synthesis_Homo sapiens_hsa049180.38191476
134Basal transcription factors_Homo sapiens_hsa030220.38091208
135Fatty acid metabolism_Homo sapiens_hsa012120.34324751
136Maturity onset diabetes of the young_Homo sapiens_hsa049500.33283667
137Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.33221482
138Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.30690181
139Sulfur relay system_Homo sapiens_hsa041220.28765476
140Type II diabetes mellitus_Homo sapiens_hsa049300.27491379
141beta-Alanine metabolism_Homo sapiens_hsa004100.27077294

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