CCDC117

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of meiosis I (GO:0060631)5.39595600
2synapsis (GO:0007129)5.39286682
3meiotic chromosome segregation (GO:0045132)5.15535707
4mitotic metaphase plate congression (GO:0007080)5.08045538
5regulation of DNA endoreduplication (GO:0032875)4.91789379
6regulation of spindle organization (GO:0090224)4.75866063
7regulation of attachment of spindle microtubules to kinetochore (GO:0051988)4.72349698
8DNA unwinding involved in DNA replication (GO:0006268)4.68065605
9piRNA metabolic process (GO:0034587)4.67842338
10purine nucleobase biosynthetic process (GO:0009113)4.62207049
11monoubiquitinated protein deubiquitination (GO:0035520)4.50473178
12regulation of histone H3-K9 methylation (GO:0051570)4.36513285
13metaphase plate congression (GO:0051310)4.35238481
14folic acid metabolic process (GO:0046655)4.34337483
15protein localization to kinetochore (GO:0034501)4.33467576
16mitotic chromosome condensation (GO:0007076)4.29603199
17nucleobase biosynthetic process (GO:0046112)4.26945154
18DNA strand elongation (GO:0022616)4.21086185
19DNA replication checkpoint (GO:0000076)4.18247858
20DNA synthesis involved in DNA repair (GO:0000731)4.16263916
21chromosome organization involved in meiosis (GO:0070192)4.15141248
22nuclear pore complex assembly (GO:0051292)4.13805321
23protein localization to chromosome, centromeric region (GO:0071459)4.13681459
24nuclear pore organization (GO:0006999)4.12872829
25mitotic nuclear envelope disassembly (GO:0007077)4.10960410
26ribosome assembly (GO:0042255)4.07375713
27attachment of spindle microtubules to kinetochore (GO:0008608)4.01211591
28positive regulation of chromosome segregation (GO:0051984)3.97555836
29vitamin transmembrane transport (GO:0035461)3.88824860
30telomere maintenance via semi-conservative replication (GO:0032201)3.87245677
31regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.85972411
32regulation of mitotic spindle organization (GO:0060236)3.84709205
33membrane disassembly (GO:0030397)3.84136847
34nuclear envelope disassembly (GO:0051081)3.84136847
35gonadal mesoderm development (GO:0007506)3.83262784
36meiotic cell cycle (GO:0051321)3.82949680
37histone H2A monoubiquitination (GO:0035518)3.81745902
38protein K6-linked ubiquitination (GO:0085020)3.78885464
39somatic hypermutation of immunoglobulin genes (GO:0016446)3.73468304
40somatic diversification of immune receptors via somatic mutation (GO:0002566)3.73468304
41resolution of meiotic recombination intermediates (GO:0000712)3.69968708
42synaptonemal complex assembly (GO:0007130)3.69029313
43regulation of centriole replication (GO:0046599)3.68316057
44mitotic sister chromatid segregation (GO:0000070)3.59466704
45establishment of chromosome localization (GO:0051303)3.58364040
46regulation of chromosome segregation (GO:0051983)3.55598422
47protein localization to chromosome (GO:0034502)3.49002782
48DNA ligation (GO:0006266)3.47700478
49gene silencing by RNA (GO:0031047)3.43390234
50DNA topological change (GO:0006265)3.42933541
51mitotic recombination (GO:0006312)3.41882422
52telomere maintenance via recombination (GO:0000722)3.40477622
53synaptonemal complex organization (GO:0070193)3.39360403
54non-recombinational repair (GO:0000726)3.35003807
55double-strand break repair via nonhomologous end joining (GO:0006303)3.35003807
56regulation of nucleobase-containing compound transport (GO:0032239)3.33631052
57male meiosis (GO:0007140)3.33544197
58cellular protein complex localization (GO:0034629)3.32779318
59protein complex localization (GO:0031503)3.31783871
60histone H3-K36 demethylation (GO:0070544)3.31482917
61negative regulation of DNA-dependent DNA replication (GO:2000104)3.29562253
62negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.29509403
63establishment of integrated proviral latency (GO:0075713)3.29368664
64ribosome biogenesis (GO:0042254)3.29115089
65DNA replication initiation (GO:0006270)3.28972436
66nuclear envelope organization (GO:0006998)3.28896205
67DNA replication-dependent nucleosome organization (GO:0034723)3.28434123
68DNA replication-dependent nucleosome assembly (GO:0006335)3.28434123
69histone H2A acetylation (GO:0043968)3.28131641
70regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.27638928
71histone exchange (GO:0043486)3.26342792
72negative regulation of mRNA processing (GO:0050686)3.23936271
73meiosis I (GO:0007127)3.23799738
74male meiosis I (GO:0007141)3.23144251
75negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.22974394
76glycine metabolic process (GO:0006544)3.22719487
77spindle checkpoint (GO:0031577)3.21006091
78regulation of helicase activity (GO:0051095)3.20894705
79DNA replication-independent nucleosome organization (GO:0034724)3.20246223
80DNA replication-independent nucleosome assembly (GO:0006336)3.20246223
81sister chromatid segregation (GO:0000819)3.20045149
82fusion of sperm to egg plasma membrane (GO:0007342)3.19631176
83pore complex assembly (GO:0046931)3.19576847
84ATP-dependent chromatin remodeling (GO:0043044)3.18516194
85histone H2A ubiquitination (GO:0033522)3.17981034
86pre-miRNA processing (GO:0031054)3.17503496
87regulation of RNA export from nucleus (GO:0046831)3.16803237
88negative regulation of histone methylation (GO:0031061)3.13438646
89heterochromatin organization (GO:0070828)3.13311347
90IMP biosynthetic process (GO:0006188)3.12008327
91nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)3.11993192
92negative regulation of chromosome segregation (GO:0051985)3.11722910
93CENP-A containing nucleosome assembly (GO:0034080)3.11537567
94meiotic nuclear division (GO:0007126)3.11495839
95mitotic sister chromatid cohesion (GO:0007064)3.09990207
96chromatin remodeling at centromere (GO:0031055)3.08857129
97positive regulation of mitotic sister chromatid separation (GO:1901970)3.08234428
98positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.08234428
99positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.08234428
100regulation of mitotic metaphase/anaphase transition (GO:0030071)3.07741083
101folic acid-containing compound biosynthetic process (GO:0009396)3.07239832
102mitotic spindle checkpoint (GO:0071174)3.07067034
103regulation of histone H3-K27 methylation (GO:0061085)3.04084783
104negative regulation of mitotic sister chromatid separation (GO:2000816)3.03638589
105negative regulation of mitotic sister chromatid segregation (GO:0033048)3.03638589
106negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.03638589
107negative regulation of sister chromatid segregation (GO:0033046)3.03638589
108regulation of centrosome cycle (GO:0046605)2.99452960
109regulation of sister chromatid cohesion (GO:0007063)2.98116938
110chromatin assembly or disassembly (GO:0006333)2.94709658
111multicellular organism reproduction (GO:0032504)2.94068323
112chromosome condensation (GO:0030261)2.94022072
113DNA methylation involved in gamete generation (GO:0043046)2.92385594
114mitotic spindle assembly checkpoint (GO:0007094)2.91266326
115folic acid transport (GO:0015884)2.90219195
116chromosome segregation (GO:0007059)2.90175238
117meiotic cell cycle process (GO:1903046)2.88555419
118spindle assembly checkpoint (GO:0071173)2.88362972
119maturation of 5.8S rRNA (GO:0000460)2.87787140
120kinetochore organization (GO:0051383)2.86066825
121regulation of mitotic sister chromatid separation (GO:0010965)2.84751311
122regulation of mitotic sister chromatid segregation (GO:0033047)2.84751311
123regulation of sister chromatid segregation (GO:0033045)2.84751311
124negative regulation of translational initiation (GO:0045947)2.84151781
125sperm-egg recognition (GO:0035036)2.83163316
126oocyte maturation (GO:0001556)2.81626846
127serine family amino acid catabolic process (GO:0009071)2.80373362
128regulation of double-strand break repair via homologous recombination (GO:0010569)2.79816716
129microtubule depolymerization (GO:0007019)2.79494953
130inner cell mass cell proliferation (GO:0001833)2.79053115
131DNA strand elongation involved in DNA replication (GO:0006271)2.78089201
132regulation of exit from mitosis (GO:0007096)2.77400233
133sister chromatid cohesion (GO:0007062)2.77395789
134cell wall macromolecule catabolic process (GO:0016998)2.75632458
135cell wall macromolecule metabolic process (GO:0044036)2.75632458

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.33041036
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.99502578
3MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse4.59727920
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.35554685
5FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.27013748
6MYC_18555785_ChIP-Seq_MESCs_Mouse3.07396855
7AR_21909140_ChIP-Seq_LNCAP_Human2.84864008
8RBPJ_22232070_ChIP-Seq_NCS_Mouse2.47346057
9MYC_19079543_ChIP-ChIP_MESCs_Mouse2.25925221
10E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.22279561
11CREB1_15753290_ChIP-ChIP_HEK293T_Human2.17461516
12JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.16914389
13EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.15883655
14MYC_19030024_ChIP-ChIP_MESCs_Mouse2.14470860
15KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.12290947
16MYC_18358816_ChIP-ChIP_MESCs_Mouse2.10150177
17* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.06781312
18GABP_17652178_ChIP-ChIP_JURKAT_Human2.05550224
19MYCN_18555785_ChIP-Seq_MESCs_Mouse2.05353616
20NELFA_20434984_ChIP-Seq_ESCs_Mouse2.04961533
21* ETS1_20019798_ChIP-Seq_JURKAT_Human2.02431654
22E2F1_21310950_ChIP-Seq_MCF-7_Human1.96522697
23EST1_17652178_ChIP-ChIP_JURKAT_Human1.91043936
24BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.88436807
25* VDR_23849224_ChIP-Seq_CD4+_Human1.84882353
26SALL1_21062744_ChIP-ChIP_HESCs_Human1.81895668
27EGR1_19374776_ChIP-ChIP_THP-1_Human1.80614455
28GABP_19822575_ChIP-Seq_HepG2_Human1.79232988
29MYC_22102868_ChIP-Seq_BL_Human1.78788370
30IGF1R_20145208_ChIP-Seq_DFB_Human1.74339270
31PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.73838703
32XRN2_22483619_ChIP-Seq_HELA_Human1.72764221
33* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.71610807
34KDM5A_27292631_Chip-Seq_BREAST_Human1.70562189
35POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.68476395
36FOXP3_21729870_ChIP-Seq_TREG_Human1.65570347
37NANOG_18555785_ChIP-Seq_MESCs_Mouse1.63568809
38KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.57844436
39KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.57844436
40KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.57844436
41KLF4_18555785_ChIP-Seq_MESCs_Mouse1.55937619
42MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.52356556
43DCP1A_22483619_ChIP-Seq_HELA_Human1.49187746
44CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.48937743
45MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.47621054
46CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.46081035
47* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.41697523
48ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.39926775
49NOTCH1_21737748_ChIP-Seq_TLL_Human1.39108578
50* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.38253562
51CIITA_25753668_ChIP-Seq_RAJI_Human1.32717247
52CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.32303743
53* KAP1_22055183_ChIP-Seq_ESCs_Mouse1.26443904
54STAT3_1855785_ChIP-Seq_MESCs_Mouse1.26396096
55DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.25387097
56FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.24974570
57ZNF263_19887448_ChIP-Seq_K562_Human1.24805289
58SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.23994024
59TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.22122175
60EWS_26573619_Chip-Seq_HEK293_Human1.21983097
61E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.20749381
62TTF2_22483619_ChIP-Seq_HELA_Human1.20473968
63SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.17963266
64HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.16032795
65SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.15964221
66NANOG_21062744_ChIP-ChIP_HESCs_Human1.14412616
67HOXB4_20404135_ChIP-ChIP_EML_Mouse1.12207205
68SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.09479628
69POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.09033429
70PADI4_21655091_ChIP-ChIP_MCF-7_Human1.06815759
71CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.05450929
72ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.02895044
73FUS_26573619_Chip-Seq_HEK293_Human1.01972718
74CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.01574952
75TP63_19390658_ChIP-ChIP_HaCaT_Human1.00996946
76* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.98932455
77IRF1_19129219_ChIP-ChIP_H3396_Human0.97870082
78TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.97346265
79POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.97197283
80GATA1_22025678_ChIP-Seq_K562_Human0.95369876
81POU5F1_16153702_ChIP-ChIP_HESCs_Human0.95126080
82SOX2_18555785_ChIP-Seq_MESCs_Mouse0.95059659
83ERG_20887958_ChIP-Seq_HPC-7_Mouse0.94464110
84BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.94148327
85TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.93456851
86WT1_19549856_ChIP-ChIP_CCG9911_Human0.92222647
87NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.92039503
88SOX17_20123909_ChIP-Seq_XEN_Mouse0.91323850
89NANOG_16153702_ChIP-ChIP_HESCs_Human0.90986836
90ESR1_15608294_ChIP-ChIP_MCF-7_Human0.90728590
91SALL4_18804426_ChIP-ChIP_XEN_Mouse0.90054403
92* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.89692655
93NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.89618900
94CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.89055401
95PPARA_22158963_ChIP-Seq_LIVER_Mouse0.88633318
96SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.88475902
97PKCTHETA_26484144_Chip-Seq_BREAST_Human0.88088221
98POU3F2_20337985_ChIP-ChIP_501MEL_Human0.87543446
99* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.86984137
100SOX2_16153702_ChIP-ChIP_HESCs_Human0.86658422
101TFEB_21752829_ChIP-Seq_HELA_Human0.86183419
102HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.83864507
103CHD1_26751641_Chip-Seq_LNCaP_Human0.83783161
104MYB_26560356_Chip-Seq_TH1_Human0.83374345
105RXR_22158963_ChIP-Seq_LIVER_Mouse0.82612646
106ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.82255169
107ELK1_19687146_ChIP-ChIP_HELA_Human0.82013150
108ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.82000177
109THAP11_20581084_ChIP-Seq_MESCs_Mouse0.81523546
110CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.81111120
111PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.81089474
112SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.80103710
113HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.79800670
114MYC_18940864_ChIP-ChIP_HL60_Human0.79760095
115TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.79144815
116* YY1_21170310_ChIP-Seq_MESCs_Mouse0.78485881
117RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.77754500
118FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.77429805
119KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.77102322
120CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.76157022
121TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.75520152
122KAP1_27257070_Chip-Seq_ESCs_Mouse0.74934699
123EGR1_23403033_ChIP-Seq_LIVER_Mouse0.74273229
124* TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse0.73866047
125MYB_21317192_ChIP-Seq_ERMYB_Mouse0.72128720
126SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.71996507
127NCOR1_26117541_ChIP-Seq_K562_Human0.71095458

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.96979567
2MP0010094_abnormal_chromosome_stability4.05823306
3MP0003111_abnormal_nucleus_morphology3.96632576
4MP0003718_maternal_effect3.48302152
5MP0004957_abnormal_blastocyst_morpholog3.44467392
6MP0003077_abnormal_cell_cycle3.43938525
7MP0008057_abnormal_DNA_replication2.85596887
8MP0008877_abnormal_DNA_methylation2.68215638
9MP0002009_preneoplasia2.59982489
10MP0008058_abnormal_DNA_repair2.50346593
11MP0009697_abnormal_copulation2.33851329
12MP0001730_embryonic_growth_arrest2.29672833
13MP0009840_abnormal_foam_cell2.26853400
14MP0001929_abnormal_gametogenesis2.15576448
15MP0008007_abnormal_cellular_replicative2.12505843
16MP0005451_abnormal_body_composition2.08500739
17MP0010307_abnormal_tumor_latency2.00645124
18MP0000350_abnormal_cell_proliferation1.96776906
19MP0002210_abnormal_sex_determination1.89703402
20MP0005380_embryogenesis_phenotype1.89571707
21MP0001672_abnormal_embryogenesis/_devel1.89571707
22MP0002653_abnormal_ependyma_morphology1.84905312
23MP0002396_abnormal_hematopoietic_system1.73828816
24MP0008260_abnormal_autophagy1.73787867
25MP0008932_abnormal_embryonic_tissue1.68767717
26MP0003984_embryonic_growth_retardation1.68534179
27MP0001697_abnormal_embryo_size1.66819613
28MP0003786_premature_aging1.65805787
29MP0002088_abnormal_embryonic_growth/wei1.64948819
30MP0000653_abnormal_sex_gland1.64258995
31MP0004264_abnormal_extraembryonic_tissu1.62859606
32MP0001145_abnormal_male_reproductive1.58478663
33MP0006035_abnormal_mitochondrial_morpho1.55545673
34MP0003123_paternal_imprinting1.53661079
35MP0005365_abnormal_bile_salt1.52365268
36MP0003941_abnormal_skin_development1.49091647
37MP0005410_abnormal_fertilization1.44340803
38MP0002080_prenatal_lethality1.43747084
39MP0005395_other_phenotype1.41774586
40MP0010234_abnormal_vibrissa_follicle1.40610831
41MP0002086_abnormal_extraembryonic_tissu1.39258299
42MP0010352_gastrointestinal_tract_polyps1.39133571
43MP0002139_abnormal_hepatobiliary_system1.38815912
44MP0002085_abnormal_embryonic_tissue1.35541997
45MP0009333_abnormal_splenocyte_physiolog1.33604301
46MP0003705_abnormal_hypodermis_morpholog1.33368669
47MP0003646_muscle_fatigue1.31791181
48MP0002084_abnormal_developmental_patter1.31588117
49MP0003699_abnormal_female_reproductive1.30792107
50MP0000490_abnormal_crypts_of1.29935915
51MP0004808_abnormal_hematopoietic_stem1.29741264
52MP0001119_abnormal_female_reproductive1.29157130
53MP0002019_abnormal_tumor_incidence1.27993456
54MP0003698_abnormal_male_reproductive1.26290648
55MP0001545_abnormal_hematopoietic_system1.23653192
56MP0005397_hematopoietic_system_phenotyp1.23653192
57MP0003119_abnormal_digestive_system1.21327699
58MP0005076_abnormal_cell_differentiation1.18865906
59MP0002161_abnormal_fertility/fecundity1.18452604
60MP0003943_abnormal_hepatobiliary_system1.18080066
61MP0003567_abnormal_fetal_cardiomyocyte1.16575613
62MP0001661_extended_life_span1.14422253
63MP0000313_abnormal_cell_death1.13402155
64MP0010678_abnormal_skin_adnexa1.12116047
65MP0003806_abnormal_nucleotide_metabolis1.09579704
66MP0004233_abnormal_muscle_weight1.08426588
67MP0003221_abnormal_cardiomyocyte_apopto1.07309017
68MP0005360_urolithiasis1.06758198
69MP0001346_abnormal_lacrimal_gland1.05672322
70MP0005647_abnormal_sex_gland1.04825905
71MP0009672_abnormal_birth_weight1.03484116
72MP0000609_abnormal_liver_physiology1.00285527
73MP0003763_abnormal_thymus_physiology0.99806537
74MP0005187_abnormal_penis_morphology0.98655505
75MP0000383_abnormal_hair_follicle0.97465957
76MP0004147_increased_porphyrin_level0.97361496
77MP0002697_abnormal_eye_size0.96239371
78MP0004185_abnormal_adipocyte_glucose0.95991526
79MP0004197_abnormal_fetal_growth/weight/0.92143670
80MP0005085_abnormal_gallbladder_physiolo0.91978664
81MP0001919_abnormal_reproductive_system0.88534930
82MP0003656_abnormal_erythrocyte_physiolo0.88067405
83MP0001188_hyperpigmentation0.88033540
84MP0003890_abnormal_embryonic-extraembry0.86195183
85MP0001849_ear_inflammation0.84136008
86MP0002877_abnormal_melanocyte_morpholog0.82744589
87MP0005621_abnormal_cell_physiology0.80789289
88MP0002233_abnormal_nose_morphology0.80035382
89MP0000703_abnormal_thymus_morphology0.79810533
90MP0002722_abnormal_immune_system0.79759565
91MP0000689_abnormal_spleen_morphology0.79412051
92MP0002398_abnormal_bone_marrow0.79078658
93MP0000358_abnormal_cell_content/0.78562818
94MP0001286_abnormal_eye_development0.77611947
95MP0002006_tumorigenesis0.76714220
96MP0005377_hearing/vestibular/ear_phenot0.75971115
97MP0003878_abnormal_ear_physiology0.75971115
98MP0000598_abnormal_liver_morphology0.75105189
99MP0001915_intracranial_hemorrhage0.74463051
100MP0002166_altered_tumor_susceptibility0.73995996
101MP0005384_cellular_phenotype0.73843990
102MP0006054_spinal_hemorrhage0.72189063
103MP0000537_abnormal_urethra_morphology0.71823739
104MP0009278_abnormal_bone_marrow0.71002073
105MP0003936_abnormal_reproductive_system0.70606150
106MP0002132_abnormal_respiratory_system0.70503142
107MP0002796_impaired_skin_barrier0.70446912
108MP0002269_muscular_atrophy0.69704122
109MP0009703_decreased_birth_body0.69540630
110MP0002138_abnormal_hepatobiliary_system0.69184615
111MP0003115_abnormal_respiratory_system0.69137342
112MP0008875_abnormal_xenobiotic_pharmacok0.68604120
113MP0001293_anophthalmia0.68389101
114MP0010329_abnormal_lipoprotein_level0.67499375
115MP0005501_abnormal_skin_physiology0.67128078
116MP0010368_abnormal_lymphatic_system0.66928416
117MP0005389_reproductive_system_phenotype0.65855864
118MP0006292_abnormal_olfactory_placode0.65671985
119MP0008995_early_reproductive_senescence0.64788073
120MP0003315_abnormal_perineum_morphology0.64147627
121MP0002160_abnormal_reproductive_system0.63772707
122MP0000733_abnormal_muscle_development0.61527872
123MP0001177_atelectasis0.61526932
124MP0002111_abnormal_tail_morphology0.61466191
125MP0003861_abnormal_nervous_system0.61243663
126MP0002092_abnormal_eye_morphology0.60875756
127MP0002429_abnormal_blood_cell0.60678852
128MP0003937_abnormal_limbs/digits/tail_de0.60357919
129MP0000627_abnormal_mammary_gland0.58219531
130MP0005220_abnormal_exocrine_pancreas0.57521435
131MP0001764_abnormal_homeostasis0.57492739
132MP0000465_gastrointestinal_hemorrhage0.57383120
133MP0003252_abnormal_bile_duct0.57231002
134MP0005666_abnormal_adipose_tissue0.57067040
135MP0002102_abnormal_ear_morphology0.56618082
136MP0004019_abnormal_vitamin_homeostasis0.55971561

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)5.14720121
2Impulsivity (HP:0100710)5.13085537
3Breast hypoplasia (HP:0003187)4.24696985
4Volvulus (HP:0002580)4.07546514
5Hyperglycinemia (HP:0002154)3.88823040
6Male infertility (HP:0003251)3.85068930
7Nephroblastoma (Wilms tumor) (HP:0002667)3.73607764
8Gonadotropin excess (HP:0000837)3.61172375
9Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.54655743
10Embryonal renal neoplasm (HP:0011794)3.51539244
11Entropion (HP:0000621)3.40976788
12Gout (HP:0001997)3.31777946
13Carpal bone hypoplasia (HP:0001498)3.22803747
14Hyperglycinuria (HP:0003108)3.16219038
15Chronic bronchitis (HP:0004469)3.11259127
16Progressive external ophthalmoplegia (HP:0000590)3.10723100
17Patellar aplasia (HP:0006443)3.08135988
18Abnormal spermatogenesis (HP:0008669)3.00840298
19Gastrointestinal carcinoma (HP:0002672)2.97519276
20Malignant gastrointestinal tract tumors (HP:0006749)2.97519276
21Facial hemangioma (HP:0000329)2.96193317
22Aplasia/Hypoplasia of the patella (HP:0006498)2.95809282
23Shoulder girdle muscle weakness (HP:0003547)2.90988261
24Abnormal lung lobation (HP:0002101)2.86072447
25Uterine leiomyosarcoma (HP:0002891)2.84285881
26Leiomyosarcoma (HP:0100243)2.84285881
27Cortical dysplasia (HP:0002539)2.78625515
28Chromsome breakage (HP:0040012)2.77079125
29Embryonal neoplasm (HP:0002898)2.74740803
30Transitional cell carcinoma of the bladder (HP:0006740)2.74539373
31Premature ovarian failure (HP:0008209)2.72819143
32Biliary tract neoplasm (HP:0100574)2.66222811
33Abnormality of chromosome stability (HP:0003220)2.64971054
34Ectopic kidney (HP:0000086)2.64533980
35Chromosomal breakage induced by crosslinking agents (HP:0003221)2.63826814
36Secondary amenorrhea (HP:0000869)2.62688873
37Capillary hemangiomas (HP:0005306)2.62101696
38Degeneration of anterior horn cells (HP:0002398)2.62071894
39Abnormality of the anterior horn cell (HP:0006802)2.62071894
40Abnormality of serine family amino acid metabolism (HP:0010894)2.61829544
41Abnormality of glycine metabolism (HP:0010895)2.61829544
42Pustule (HP:0200039)2.58954302
43Prominent nose (HP:0000448)2.57524248
44Abnormality of chromosome segregation (HP:0002916)2.55974958
45Hereditary nonpolyposis colorectal carcinoma (HP:0006716)2.55633183
46Bladder carcinoma (HP:0002862)2.54324038
47Bladder neoplasm (HP:0009725)2.54324038
48Hypoplasia of the capital femoral epiphysis (HP:0003090)2.53036837
49Oral leukoplakia (HP:0002745)2.51643857
50Agnosia (HP:0010524)2.51450330
51Overlapping toe (HP:0001845)2.50183713
52Azoospermia (HP:0000027)2.48096248
53Infertility (HP:0000789)2.47993506
54Neoplasm of the colon (HP:0100273)2.47261423
55Nasal polyposis (HP:0100582)2.44956975
56Areflexia of lower limbs (HP:0002522)2.43988466
57Deep philtrum (HP:0002002)2.42829891
58Rhabdomyosarcoma (HP:0002859)2.42681245
59Osteomalacia (HP:0002749)2.42606754
60Rhinitis (HP:0012384)2.41623593
61Ependymoma (HP:0002888)2.39258696
62Microvesicular hepatic steatosis (HP:0001414)2.36003484
63Sparse lateral eyebrow (HP:0005338)2.35374414
64Uterine neoplasm (HP:0010784)2.34558708
65Amyotrophic lateral sclerosis (HP:0007354)2.34117524
66Rough bone trabeculation (HP:0100670)2.33401895
67Progressive muscle weakness (HP:0003323)2.33121962
68Proximal tubulopathy (HP:0000114)2.32616116
69Abnormality of lateral ventricle (HP:0030047)2.32589658
70Abnormality of the preputium (HP:0100587)2.32559098
71Polycythemia (HP:0001901)2.31901903
72Abnormality of the duodenum (HP:0002246)2.29698252
73Ureteral duplication (HP:0000073)2.29203348
74Abnormality of serum amino acid levels (HP:0003112)2.28928360
75Hepatoblastoma (HP:0002884)2.28829674
76Breast carcinoma (HP:0003002)2.27149480
77Proximal placement of thumb (HP:0009623)2.25941608
78Neoplasm of the small intestine (HP:0100833)2.24210710
79Multiple enchondromatosis (HP:0005701)2.24094914
80Meckel diverticulum (HP:0002245)2.23704919
81Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.23229842
82Aplasia/Hypoplasia of the uvula (HP:0010293)2.22216913
83Rimmed vacuoles (HP:0003805)2.21856783
84Glioma (HP:0009733)2.19608818
85Selective tooth agenesis (HP:0001592)2.18338039
86Aplasia/Hypoplasia of the sternum (HP:0006714)2.18154369
87Sloping forehead (HP:0000340)2.15907222
88Acute myeloid leukemia (HP:0004808)2.13363750
89Thyroid carcinoma (HP:0002890)2.11455783
90Microretrognathia (HP:0000308)2.10261081
91Papillary thyroid carcinoma (HP:0002895)2.09709838
92Bronchitis (HP:0012387)2.09142127
93Cystic hygroma (HP:0000476)2.08230779
94Hyperglycemia (HP:0003074)2.07885788
95Abnormality of the labia minora (HP:0012880)2.07105000
96Horizontal nystagmus (HP:0000666)2.07098444
97Atrophy/Degeneration involving motor neurons (HP:0007373)2.07014261
98Increased nuchal translucency (HP:0010880)2.06500174
99Myelodysplasia (HP:0002863)2.05805564
100Deviation of the thumb (HP:0009603)2.04694149
101Abnormality of the carotid arteries (HP:0005344)2.04387397
102Abnormality of the nasal mucosa (HP:0000433)2.03566292
103Absent radius (HP:0003974)2.02126874
104Posterior subcapsular cataract (HP:0007787)2.02076119
105Squamous cell carcinoma (HP:0002860)2.01947419
106Medulloblastoma (HP:0002885)2.01460315
107Cerebral hypomyelination (HP:0006808)2.01350011
108Duodenal stenosis (HP:0100867)2.00662877
109Small intestinal stenosis (HP:0012848)2.00662877
110Deep venous thrombosis (HP:0002625)2.00422399
111Abnormality of the ileum (HP:0001549)1.99643394
112Short middle phalanx of the 5th finger (HP:0004220)1.97277512
113Abnormality of DNA repair (HP:0003254)1.94981795
114Hyperuricemia (HP:0002149)1.93454545
115Increased purine levels (HP:0004368)1.93454545
116Acanthocytosis (HP:0001927)1.92846392
117Oligodactyly (hands) (HP:0001180)1.92066809
118Cafe-au-lait spot (HP:0000957)1.91911783
119Tetraplegia (HP:0002445)1.90048726
120Upper motor neuron abnormality (HP:0002127)1.89966904
121Hypobetalipoproteinemia (HP:0003563)1.89061957
122Horseshoe kidney (HP:0000085)1.88312957
123Global brain atrophy (HP:0002283)1.87633066
124Bone marrow hypocellularity (HP:0005528)1.86472728
125Triphalangeal thumb (HP:0001199)1.86191889
126Absent forearm bone (HP:0003953)1.86051708
127Aplasia involving forearm bones (HP:0009822)1.86051708
128Neoplasm of the pancreas (HP:0002894)1.85700233
129Neoplasm of striated muscle (HP:0009728)1.85568276
130Insulin-resistant diabetes mellitus (HP:0000831)1.84752085
131Abnormality of the fingertips (HP:0001211)1.84114757
132Neoplasm of the adrenal cortex (HP:0100641)1.83984903
133Pancreatic islet-cell hyperplasia (HP:0004510)1.83886977
134Atrioventricular block (HP:0001678)1.83737050
135Bronchiectasis (HP:0002110)1.83312540
136Colon cancer (HP:0003003)1.83234025
137Arteriovenous malformation (HP:0100026)1.83132081
138Ovarian neoplasm (HP:0100615)1.82694878
139Choanal atresia (HP:0000453)1.81978655
140Clubbing of toes (HP:0100760)1.81790531
141Basal cell carcinoma (HP:0002671)1.81402970
142Absent epiphyses (HP:0010577)1.79683397
143Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.79683397
144Sandal gap (HP:0001852)1.79446164
145Abnormal respiratory motile cilium physiology (HP:0012261)1.79320678
146Difficulty climbing stairs (HP:0003551)1.78657518
147Supernumerary spleens (HP:0009799)1.77683307
148Neoplasm of the rectum (HP:0100743)1.77415640
149Pelvic girdle muscle weakness (HP:0003749)1.75658841
150Oligodactyly (HP:0012165)1.75511372
151Flat capital femoral epiphysis (HP:0003370)1.75375535
152Breast aplasia (HP:0100783)1.74767895
153Conjunctival telangiectasia (HP:0000524)1.74058194
154Microglossia (HP:0000171)1.72540495
155Bundle branch block (HP:0011710)1.70741770
15611 pairs of ribs (HP:0000878)1.70245492
157Reticulocytopenia (HP:0001896)1.69595825
158Personality changes (HP:0000751)1.69567789
159High anterior hairline (HP:0009890)1.69367714
160Abnormal protein glycosylation (HP:0012346)1.67600365
161Abnormal glycosylation (HP:0012345)1.67600365
162Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.67600365
163Abnormal protein N-linked glycosylation (HP:0012347)1.67600365
164Abnormality of the astrocytes (HP:0100707)1.67599608
165Astrocytoma (HP:0009592)1.67599608

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.31069155
2NEK23.75068382
3WEE13.64475852
4PLK43.03800954
5PDK43.01359617
6PDK33.01359617
7CDC72.94345338
8BRD42.73461132
9CDK192.67369917
10TAF12.62837014
11TTK2.47549059
12LATS12.43241456
13BRSK22.40927781
14TAOK32.38369706
15ACVR1B2.22357555
16STK32.21110973
17EIF2AK11.96949365
18TSSK61.86153676
19PLK11.85698543
20PDK21.83773985
21NEK11.82816738
22CHEK21.74924939
23STK101.69866624
24CDK121.66833879
25PBK1.66719501
26STK38L1.66040676
27ZAK1.60956773
28AKT31.56340118
29MOS1.54442920
30DYRK31.52958821
31CDK41.52799706
32CAMK1G1.50856256
33LATS21.50506811
34SCYL21.49143480
35YES11.48575467
36EEF2K1.36611607
37AURKB1.34530653
38CDK71.30073441
39MAP3K81.26372623
40TRIM281.23860280
41BRSK11.22660304
42RPS6KA41.22075791
43PLK31.21213294
44MELK1.20234414
45SRPK11.15893054
46FGR1.13760051
47CHEK11.10700348
48ERBB31.07594610
49NME21.06366176
50MAP3K41.06049109
51TRIB31.04616171
52ATR0.99644046
53BCR0.98250754
54MKNK20.97057061
55PLK20.96581791
56EIF2AK30.93344395
57MST40.92651135
58BMPR20.90056308
59TAOK10.88384088
60PIM10.86884076
61MAP4K10.86383877
62MET0.85332564
63MAP3K60.83096775
64BRAF0.81308157
65CCNB10.80934972
66AURKA0.80140924
67PKN20.78096693
68MTOR0.75610685
69RPS6KB10.74694219
70CDK60.74170958
71EPHA20.71111314
72ATM0.70685736
73EIF2AK20.70380395
74NLK0.69431389
75CDK20.68788271
76CDK80.65165362
77PRKAA10.64961526
78RAF10.64829182
79MAP3K140.64127712
80CLK10.63707746
81RPS6KB20.63547125
82STK40.63362657
83NUAK10.62215527
84MKNK10.61846987
85CSNK1G10.59001352
86SMG10.58404213
87PASK0.56614293
88PINK10.56394799
89ALK0.56339903
90CDK90.55406874
91MAP3K20.54892727
92STK240.54455060
93CSF1R0.54351290
94TESK20.53848614
95PNCK0.51402142
96MARK30.51074127
97ZAP700.50505749
98KSR10.49944246
99FGFR40.49726500
100TYK20.49111891
101CDK11A0.49085962
102MAP3K50.48842522
103CDK10.47888470
104NEK60.46718368
105VRK10.45933904
106FLT30.45051207
107STK380.44985381
108MAPK110.44701533
109BCKDK0.44558464
110PRKD30.43376436
111MAP3K100.42882228
112KSR20.42690450
113CSNK2A10.41950840
114NEK90.41604618
115PRKCI0.41256670
116LRRK20.40999163
117CSNK1G20.40675368
118CSNK1E0.40509611
119MAP2K30.40151854
120PAK10.39654380
121OXSR10.38298965
122MAP3K30.37140192
123STK390.36957961
124BMX0.36642324
125FGFR10.36481662
126CSNK1G30.36279521
127MAP3K90.34984178
128CDK180.34608231
129ARAF0.33382327
130CDK150.32998283
131DYRK1B0.32943757
132PAK40.32702154
133PRKDC0.32699220
134CSNK2A20.25585355
135CDK30.25245590
136CSNK1A1L0.25013780
137ICK0.23994687
138AKT20.23321566

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007505.06629958
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.53126212
3RNA transport_Homo sapiens_hsa030132.99725014
4DNA replication_Homo sapiens_hsa030302.91721396
5Cell cycle_Homo sapiens_hsa041102.88740181
6RNA polymerase_Homo sapiens_hsa030202.75426573
7Basal transcription factors_Homo sapiens_hsa030222.54531699
8Folate biosynthesis_Homo sapiens_hsa007902.37983577
9Mismatch repair_Homo sapiens_hsa034302.34553210
10Homologous recombination_Homo sapiens_hsa034402.21263202
11Base excision repair_Homo sapiens_hsa034102.13436830
12Pentose phosphate pathway_Homo sapiens_hsa000301.92034818
13Spliceosome_Homo sapiens_hsa030401.90742414
14Nucleotide excision repair_Homo sapiens_hsa034201.86624281
15Fanconi anemia pathway_Homo sapiens_hsa034601.85607657
16Cysteine and methionine metabolism_Homo sapiens_hsa002701.83813415
17Pyrimidine metabolism_Homo sapiens_hsa002401.83311430
18p53 signaling pathway_Homo sapiens_hsa041151.80922128
19Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.80851292
20Selenocompound metabolism_Homo sapiens_hsa004501.79153312
21RNA degradation_Homo sapiens_hsa030181.60717560
22Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.52859389
23Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.50347296
24One carbon pool by folate_Homo sapiens_hsa006701.48913023
25mRNA surveillance pathway_Homo sapiens_hsa030151.48209584
26Drug metabolism - other enzymes_Homo sapiens_hsa009831.47697266
27Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.41482897
28Biosynthesis of amino acids_Homo sapiens_hsa012301.40722470
29Oocyte meiosis_Homo sapiens_hsa041141.39223244
30Regulation of autophagy_Homo sapiens_hsa041401.36448420
31Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.30419010
32Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.21732698
33Glycerophospholipid metabolism_Homo sapiens_hsa005641.20792486
34Sulfur relay system_Homo sapiens_hsa041221.19650041
35Non-homologous end-joining_Homo sapiens_hsa034501.18000394
36Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.14405761
37Purine metabolism_Homo sapiens_hsa002301.12621271
38Antigen processing and presentation_Homo sapiens_hsa046121.10551489
39Vitamin digestion and absorption_Homo sapiens_hsa049771.06201880
40Steroid biosynthesis_Homo sapiens_hsa001001.05201051
41Proteasome_Homo sapiens_hsa030501.05139769
42Circadian rhythm_Homo sapiens_hsa047101.01112750
43Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.93147007
44Epstein-Barr virus infection_Homo sapiens_hsa051690.92553886
45Prostate cancer_Homo sapiens_hsa052150.91084876
46Colorectal cancer_Homo sapiens_hsa052100.89207928
47Carbon metabolism_Homo sapiens_hsa012000.85449953
48Herpes simplex infection_Homo sapiens_hsa051680.84386441
49Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.84247729
50mTOR signaling pathway_Homo sapiens_hsa041500.77833464
51Adherens junction_Homo sapiens_hsa045200.75664110
52Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.74885987
53Viral carcinogenesis_Homo sapiens_hsa052030.71237766
54Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.69365047
55N-Glycan biosynthesis_Homo sapiens_hsa005100.69068373
56Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.68003877
57Endometrial cancer_Homo sapiens_hsa052130.65937073
58Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.65302029
59Renin-angiotensin system_Homo sapiens_hsa046140.64227359
60Primary bile acid biosynthesis_Homo sapiens_hsa001200.63659224
61Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.62973962
62Bladder cancer_Homo sapiens_hsa052190.62265880
63MicroRNAs in cancer_Homo sapiens_hsa052060.60045823
64Fatty acid metabolism_Homo sapiens_hsa012120.58830169
65Glycerolipid metabolism_Homo sapiens_hsa005610.58687327
66RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.56328011
67Systemic lupus erythematosus_Homo sapiens_hsa053220.55699019
68Wnt signaling pathway_Homo sapiens_hsa043100.53897790
69Thyroid cancer_Homo sapiens_hsa052160.53687710
70Small cell lung cancer_Homo sapiens_hsa052220.53628400
71HTLV-I infection_Homo sapiens_hsa051660.53054578
72Linoleic acid metabolism_Homo sapiens_hsa005910.52153007
73FoxO signaling pathway_Homo sapiens_hsa040680.51891549
74Lysine degradation_Homo sapiens_hsa003100.49738261
75Protein export_Homo sapiens_hsa030600.48375242
76Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.48299492
77alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.48254113
78Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.47098664
79Non-small cell lung cancer_Homo sapiens_hsa052230.46321720
80Longevity regulating pathway - mammal_Homo sapiens_hsa042110.45979979
81Fatty acid degradation_Homo sapiens_hsa000710.45732682
82Propanoate metabolism_Homo sapiens_hsa006400.45586838
832-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.45136158
84Arginine biosynthesis_Homo sapiens_hsa002200.43712969
85Dorso-ventral axis formation_Homo sapiens_hsa043200.43652103
86Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.43322686
87Hippo signaling pathway_Homo sapiens_hsa043900.42280671
88Measles_Homo sapiens_hsa051620.42235322
89Central carbon metabolism in cancer_Homo sapiens_hsa052300.41866322
90Fructose and mannose metabolism_Homo sapiens_hsa000510.40881315
91Pentose and glucuronate interconversions_Homo sapiens_hsa000400.39875274
92Acute myeloid leukemia_Homo sapiens_hsa052210.39122071
93AMPK signaling pathway_Homo sapiens_hsa041520.39030485
94Retinol metabolism_Homo sapiens_hsa008300.38222602
95Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.37982981
96ErbB signaling pathway_Homo sapiens_hsa040120.37319775
97Maturity onset diabetes of the young_Homo sapiens_hsa049500.36857048
98Chronic myeloid leukemia_Homo sapiens_hsa052200.36211352
99Pyruvate metabolism_Homo sapiens_hsa006200.34866317
100TGF-beta signaling pathway_Homo sapiens_hsa043500.34259838
101Complement and coagulation cascades_Homo sapiens_hsa046100.33977934
102Influenza A_Homo sapiens_hsa051640.33526201
103PPAR signaling pathway_Homo sapiens_hsa033200.31165546
104Shigellosis_Homo sapiens_hsa051310.31144639
105Primary immunodeficiency_Homo sapiens_hsa053400.30811681
106Inositol phosphate metabolism_Homo sapiens_hsa005620.29493192
107Glutathione metabolism_Homo sapiens_hsa004800.28787504
108Ovarian steroidogenesis_Homo sapiens_hsa049130.28684008
109beta-Alanine metabolism_Homo sapiens_hsa004100.28453997
110Insulin resistance_Homo sapiens_hsa049310.28343124
111Nitrogen metabolism_Homo sapiens_hsa009100.28020898
112Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.27721273
113Basal cell carcinoma_Homo sapiens_hsa052170.27454254
114Transcriptional misregulation in cancer_Homo sapiens_hsa052020.26854000
115Metabolic pathways_Homo sapiens_hsa011000.26567162
116Legionellosis_Homo sapiens_hsa051340.26518911
117Caffeine metabolism_Homo sapiens_hsa002320.25862852
118Ribosome_Homo sapiens_hsa030100.25424728
119Pancreatic cancer_Homo sapiens_hsa052120.24945132
120Insulin signaling pathway_Homo sapiens_hsa049100.24540093
121Glucagon signaling pathway_Homo sapiens_hsa049220.24223322
122Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.24043529
123Prolactin signaling pathway_Homo sapiens_hsa049170.24029726
124Thyroid hormone signaling pathway_Homo sapiens_hsa049190.23610786
125Sphingolipid metabolism_Homo sapiens_hsa006000.23521318
126Apoptosis_Homo sapiens_hsa042100.22766422
127Tryptophan metabolism_Homo sapiens_hsa003800.22631871
128Hepatitis B_Homo sapiens_hsa051610.22057769
129Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.20426614
130Choline metabolism in cancer_Homo sapiens_hsa052310.20357305

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