CCDC121

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ventricular system development (GO:0021591)9.41015290
2UTP biosynthetic process (GO:0006228)9.40966990
3UTP metabolic process (GO:0046051)8.68922139
4epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)8.01617272
5guanosine-containing compound biosynthetic process (GO:1901070)6.86480662
6CTP biosynthetic process (GO:0006241)6.86223745
7CTP metabolic process (GO:0046036)6.86223745
8left/right axis specification (GO:0070986)6.47145545
9pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)6.32690521
10microtubule bundle formation (GO:0001578)6.03129551
11nucleotide phosphorylation (GO:0046939)6.01721870
12pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)5.97924162
13intraciliary transport (GO:0042073)5.69976357
14cilium organization (GO:0044782)5.41300195
15pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)5.18755385
16V(D)J recombination (GO:0033151)5.17193770
17regulation of meiosis I (GO:0060631)5.17148936
18nucleoside diphosphate metabolic process (GO:0009132)5.07657662
19deoxyribonucleoside diphosphate metabolic process (GO:0009186)4.95618789
20piRNA metabolic process (GO:0034587)4.93297033
21cilium assembly (GO:0042384)4.90344110
22ADP metabolic process (GO:0046031)4.74747988
23regulation of glucose import in response to insulin stimulus (GO:2001273)4.71898256
24retinal cone cell development (GO:0046549)4.56610228
25pyrimidine nucleoside triphosphate metabolic process (GO:0009147)4.55575756
26microtubule-based movement (GO:0007018)4.54181391
27regulation of macrophage chemotaxis (GO:0010758)4.48359255
28motile cilium assembly (GO:0044458)4.45243461
29oxygen transport (GO:0015671)4.34847656
30centriole replication (GO:0007099)4.33656813
31cellular component assembly involved in morphogenesis (GO:0010927)4.31315585
32synapsis (GO:0007129)4.25678601
33negative regulation of thymocyte apoptotic process (GO:0070244)4.16517101
34neuron fate determination (GO:0048664)4.15078646
35pyrimidine ribonucleoside biosynthetic process (GO:0046132)4.11416781
36resolution of meiotic recombination intermediates (GO:0000712)4.10191966
37cilium morphogenesis (GO:0060271)4.09913751
38pyrimidine ribonucleotide biosynthetic process (GO:0009220)3.98548429
39histone H2A acetylation (GO:0043968)3.93804021
40chromosome organization involved in meiosis (GO:0070192)3.88328808
41regulation of mononuclear cell migration (GO:0071675)3.88233906
42purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.87031985
43male meiosis I (GO:0007141)3.82763887
44meiotic cell cycle (GO:0051321)3.81644837
45cell projection assembly (GO:0030031)3.77503077
46DNA methylation involved in gamete generation (GO:0043046)3.76427986
47purine nucleoside triphosphate biosynthetic process (GO:0009145)3.76301124
48synaptonemal complex assembly (GO:0007130)3.71676641
49positive regulation of cellular response to insulin stimulus (GO:1900078)3.68141809
50binding of sperm to zona pellucida (GO:0007339)3.67914203
51synaptonemal complex organization (GO:0070193)3.65635778
52acrosome reaction (GO:0007340)3.57686368
53pyrimidine ribonucleotide metabolic process (GO:0009218)3.54390213
54spermatid nucleus differentiation (GO:0007289)3.52433966
55purine deoxyribonucleoside triphosphate metabolic process (GO:0009215)3.50717600
56positive regulation of meiosis (GO:0045836)3.48982540
57cellular response to nicotine (GO:0071316)3.43563873
58axon ensheathment in central nervous system (GO:0032291)3.43177830
59central nervous system myelination (GO:0022010)3.43177830
60male meiosis (GO:0007140)3.41147404
61brain morphogenesis (GO:0048854)3.39568352
62nucleoside triphosphate biosynthetic process (GO:0009142)3.35933322
63centriole assembly (GO:0098534)3.35777783
64positive regulation of respiratory burst (GO:0060267)3.35295269
65gas transport (GO:0015669)3.33596743
66sperm-egg recognition (GO:0035036)3.31447736
67ribonucleoside triphosphate biosynthetic process (GO:0009201)3.28787713
68histone monoubiquitination (GO:0010390)3.28505554
69phosphorylated carbohydrate dephosphorylation (GO:0046838)3.25570569
70inositol phosphate dephosphorylation (GO:0046855)3.25570569
71regulation of female gonad development (GO:2000194)3.24584373
72response to pheromone (GO:0019236)3.24045019
73somite rostral/caudal axis specification (GO:0032525)3.22302799
74determination of left/right symmetry (GO:0007368)3.21809236
75regulation of cilium movement (GO:0003352)3.21528334
76epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)3.21334393
77one-carbon compound transport (GO:0019755)3.20629208
78positive regulation of meiotic cell cycle (GO:0051446)3.17911990
79photoreceptor cell maintenance (GO:0045494)3.17258936
80response to hydroperoxide (GO:0033194)3.17025404
81spermatid development (GO:0007286)3.09870936
82oocyte development (GO:0048599)3.09612760
83multicellular organism reproduction (GO:0032504)3.09068432
84mitotic sister chromatid cohesion (GO:0007064)3.08653178
85determination of bilateral symmetry (GO:0009855)3.08242054
86pyrimidine ribonucleoside metabolic process (GO:0046131)3.07978104
87nonmotile primary cilium assembly (GO:0035058)3.06505095
88regulation of DNA methylation (GO:0044030)3.06317388
89kinetochore organization (GO:0051383)3.04401512
90monoubiquitinated protein deubiquitination (GO:0035520)3.04205381
91inositol phosphate catabolic process (GO:0071545)3.04168984
92meiotic cell cycle process (GO:1903046)3.03246727
93sister chromatid cohesion (GO:0007062)3.02487329
94specification of symmetry (GO:0009799)3.02044197
95pyrimidine nucleotide biosynthetic process (GO:0006221)3.00863625
96sperm motility (GO:0030317)3.00509437
97female gamete generation (GO:0007292)2.95926832
98primitive streak formation (GO:0090009)2.95204622
99meiosis I (GO:0007127)2.94091360
100multicellular organismal aging (GO:0010259)2.92187018
101histone exchange (GO:0043486)2.89618995
102kinetochore assembly (GO:0051382)2.89414885
103microtubule depolymerization (GO:0007019)2.88949193
104protein localization to chromosome (GO:0034502)2.88829912
105negative regulation of B cell mediated immunity (GO:0002713)2.88333744
106negative regulation of immunoglobulin mediated immune response (GO:0002890)2.88333744
107positive regulation of gastrulation (GO:2000543)2.87310375
108protein prenylation (GO:0018342)2.86134830
109prenylation (GO:0097354)2.86134830
110fertilization (GO:0009566)2.84000538
111meiotic nuclear division (GO:0007126)2.83838835
112female mating behavior (GO:0060180)2.82945131
113short-chain fatty acid metabolic process (GO:0046459)2.81964543
114purine ribonucleoside diphosphate metabolic process (GO:0009179)2.81054067
115purine nucleoside diphosphate metabolic process (GO:0009135)2.81054067
116acrosome assembly (GO:0001675)2.80468800
117single fertilization (GO:0007338)2.78265246
118gene silencing by RNA (GO:0031047)2.77973048
119protein localization to kinetochore (GO:0034501)2.74839466
120CENP-A containing nucleosome assembly (GO:0034080)2.71071129
121cellular response to ethanol (GO:0071361)2.70849492
122embryonic digestive tract development (GO:0048566)2.70127785
123regulation of mesenchymal cell apoptotic process (GO:2001053)2.68993443
124mitotic metaphase plate congression (GO:0007080)2.66944164
125regulation of meiosis (GO:0040020)2.65180109
126fusion of sperm to egg plasma membrane (GO:0007342)2.63674267
127positive regulation of histone H3-K4 methylation (GO:0051571)2.63335516
128regulation of meiotic cell cycle (GO:0051445)2.62724236
129pyrimidine nucleoside biosynthetic process (GO:0046134)2.61375944
130somatic diversification of immune receptors via germline recombination within a single locus (GO:0002.60954693
131somatic cell DNA recombination (GO:0016444)2.60954693
132cell-cell recognition (GO:0009988)2.60508881
133regulation of glucokinase activity (GO:0033131)2.59488903
134regulation of hexokinase activity (GO:1903299)2.59488903
135cullin deneddylation (GO:0010388)2.58852673
136chromatin remodeling at centromere (GO:0031055)2.58386276
137regulation of histone H3-K9 methylation (GO:0051570)2.57576109
138S-adenosylmethionine metabolic process (GO:0046500)2.57291499
139histone ubiquitination (GO:0016574)2.56923409
140otic vesicle formation (GO:0030916)2.55935028
141negative regulation of hormone biosynthetic process (GO:0032353)2.55639513
142smoothened signaling pathway (GO:0007224)2.55076144
143left/right pattern formation (GO:0060972)2.54095719
144response to methylmercury (GO:0051597)2.53940066
145microtubule polymerization or depolymerization (GO:0031109)2.52342573
146glomerular epithelial cell development (GO:0072310)2.52321502
147nonribosomal peptide biosynthetic process (GO:0019184)2.51607065
148photoreceptor cell differentiation (GO:0046530)2.51429093
149eye photoreceptor cell differentiation (GO:0001754)2.51429093
150protein monoubiquitination (GO:0006513)2.51416086
151DNA integration (GO:0015074)2.51036035
152histone H3-K9 demethylation (GO:0033169)2.49978317
153regulation of cell maturation (GO:1903429)2.48792979
154AMP metabolic process (GO:0046033)2.46809146
155negative regulation of transcription regulatory region DNA binding (GO:2000678)2.41574348
156cerebral cortex neuron differentiation (GO:0021895)2.37289941
157negative regulation of humoral immune response (GO:0002921)2.36594870
158protein palmitoylation (GO:0018345)2.30645722
159regulation of pigment cell differentiation (GO:0050932)2.29141614
160regulation of microtubule-based movement (GO:0060632)2.28005170
161cysteine metabolic process (GO:0006534)2.23948289
162deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.22031483
163cartilage morphogenesis (GO:0060536)2.21076389
164retinal rod cell development (GO:0046548)2.20812977
165establishment of protein localization to mitochondrial membrane (GO:0090151)2.20775148
166microtubule-based process (GO:0007017)2.19602273
167negative regulation of astrocyte differentiation (GO:0048712)2.18955984
168detection of calcium ion (GO:0005513)2.18293862
169purine deoxyribonucleotide metabolic process (GO:0009151)2.16248513
170positive regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043517)2.16056621
171protein localization to cilium (GO:0061512)2.15901473
172pyrimidine-containing compound biosynthetic process (GO:0072528)2.14423105
173secondary metabolite biosynthetic process (GO:0044550)2.13470017
174ribonucleoside diphosphate metabolic process (GO:0009185)2.13299031
175cilium movement (GO:0003341)16.0610781
176axoneme assembly (GO:0035082)13.3359764
177cilium or flagellum-dependent cell motility (GO:0001539)11.7684596
178axonemal dynein complex assembly (GO:0070286)11.2271321
179epithelial cilium movement (GO:0003351)11.0241378
180nucleoside diphosphate phosphorylation (GO:0006165)11.0155471
181GTP biosynthetic process (GO:0006183)10.4674115

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.82865845
2RBPJ_22232070_ChIP-Seq_NCS_Mouse3.76369290
3CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human3.64627820
4CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.61323509
5E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.34286504
6SALL1_21062744_ChIP-ChIP_HESCs_Human3.03136989
7AR_21572438_ChIP-Seq_LNCaP_Human2.86151589
8ZNF274_21170338_ChIP-Seq_K562_Hela2.49229614
9CTBP2_25329375_ChIP-Seq_LNCAP_Human2.26703379
10GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.21240882
11IGF1R_20145208_ChIP-Seq_DFB_Human2.15120180
12JARID2_20064375_ChIP-Seq_MESCs_Mouse2.09066589
13SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.05646372
14MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.01482904
15ER_23166858_ChIP-Seq_MCF-7_Human1.97656930
16KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.95059879
17EZH2_27304074_Chip-Seq_ESCs_Mouse1.94553691
18BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.93443746
19P300_19829295_ChIP-Seq_ESCs_Human1.92917459
20POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.92827104
21TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.92827104
22SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.92643404
23VDR_22108803_ChIP-Seq_LS180_Human1.90570883
24CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.88726063
25SMAD4_21799915_ChIP-Seq_A2780_Human1.85753132
26SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.83237710
27PADI4_21655091_ChIP-ChIP_MCF-7_Human1.83091996
28GATA1_26923725_Chip-Seq_HPCs_Mouse1.82604018
29JARID2_20075857_ChIP-Seq_MESCs_Mouse1.81626747
30GABP_17652178_ChIP-ChIP_JURKAT_Human1.79471781
31SMAD_19615063_ChIP-ChIP_OVARY_Human1.78973644
32EZH2_27294783_Chip-Seq_ESCs_Mouse1.78616331
33EZH2_22144423_ChIP-Seq_EOC_Human1.78403511
34PIAS1_25552417_ChIP-Seq_VCAP_Human1.77128757
35TP63_19390658_ChIP-ChIP_HaCaT_Human1.76286487
36RNF2_18974828_ChIP-Seq_MESCs_Mouse1.74935829
37EZH2_18974828_ChIP-Seq_MESCs_Mouse1.74935829
38MYC_18940864_ChIP-ChIP_HL60_Human1.74801308
39CTBP1_25329375_ChIP-Seq_LNCAP_Human1.74644963
40FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.73386905
41* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.73291607
42EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.73227534
43SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.72754832
44OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.71563293
45TRIM28_21343339_ChIP-Seq_HEK293_Human1.70528796
46MTF2_20144788_ChIP-Seq_MESCs_Mouse1.69536521
47EST1_17652178_ChIP-ChIP_JURKAT_Human1.66782329
48SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.66533300
49* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.65955229
50DROSHA_22980978_ChIP-Seq_HELA_Human1.65165683
51SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.64780311
52ELK1_19687146_ChIP-ChIP_HELA_Human1.61746141
53AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.61527887
54SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.61489713
55CDX2_19796622_ChIP-Seq_MESCs_Mouse1.61320155
56PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.61148607
57UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.58634860
58* RNF2_27304074_Chip-Seq_NSC_Mouse1.57940928
59NR3C1_21868756_ChIP-Seq_MCF10A_Human1.57678149
60BCAT_22108803_ChIP-Seq_LS180_Human1.56472155
61EED_16625203_ChIP-ChIP_MESCs_Mouse1.55098184
62MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.53321152
63MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.50171926
64TOP2B_26459242_ChIP-Seq_MCF-7_Human1.48670892
65MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.46910540
66CBX2_27304074_Chip-Seq_ESCs_Mouse1.45070049
67TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.44682405
68* SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.44629277
69BMI1_23680149_ChIP-Seq_NPCS_Mouse1.44326620
70POU3F2_20337985_ChIP-ChIP_501MEL_Human1.43491848
71TAF15_26573619_Chip-Seq_HEK293_Human1.43109052
72RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.43095881
73SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.41749208
74NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.40598499
75GBX2_23144817_ChIP-Seq_PC3_Human1.40576342
76PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.39667508
77PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.37166655
78RNF2_27304074_Chip-Seq_ESCs_Mouse1.36913214
79SMAD3_21741376_ChIP-Seq_EPCs_Human1.35092986
80MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.33535775
81E2F4_17652178_ChIP-ChIP_JURKAT_Human1.33067994
82RXR_22108803_ChIP-Seq_LS180_Human1.31060717
83P53_22127205_ChIP-Seq_FIBROBLAST_Human1.30431953
84KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.28954619
85* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.27815713
86TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.27088337
87FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.26124018
88* LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.25983507
89TCF4_22108803_ChIP-Seq_LS180_Human1.24683968
90TP53_22573176_ChIP-Seq_HFKS_Human1.23600997
91GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.22791975
92SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.19658759
93TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.19457956
94ZFP57_27257070_Chip-Seq_ESCs_Mouse1.19118752
95TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.18522715
96VDR_23849224_ChIP-Seq_CD4+_Human1.16502643
97STAT3_23295773_ChIP-Seq_U87_Human1.16494885
98FLI1_21867929_ChIP-Seq_TH2_Mouse1.16410881
99SMAD4_21741376_ChIP-Seq_EPCs_Human1.16382521
100FOXA1_25329375_ChIP-Seq_VCAP_Human1.16034461
101FOXA1_27270436_Chip-Seq_PROSTATE_Human1.16034461
102REST_21632747_ChIP-Seq_MESCs_Mouse1.15548842
103LMO2_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.14935879
104ZNF217_24962896_ChIP-Seq_MCF-7_Human1.13587751
105FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.13587018
106CREB1_15753290_ChIP-ChIP_HEK293T_Human1.13282039
107EWS_26573619_Chip-Seq_HEK293_Human1.10245082
108AUTS2_25519132_ChIP-Seq_293T-REX_Human1.09555294
109RING1B_27294783_Chip-Seq_ESCs_Mouse1.09035005
110KLF5_20875108_ChIP-Seq_MESCs_Mouse1.08903153
111GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.08744119
112SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.08313335
113FUS_26573619_Chip-Seq_HEK293_Human1.08126445
114WT1_19549856_ChIP-ChIP_CCG9911_Human1.07984115
115RUNX2_22187159_ChIP-Seq_PCA_Human1.07734930
116ARNT_22903824_ChIP-Seq_MCF-7_Human1.07579875
117HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.06835757
118AR_20517297_ChIP-Seq_VCAP_Human1.06764192
119NANOG_19829295_ChIP-Seq_ESCs_Human1.06744694
120SOX2_19829295_ChIP-Seq_ESCs_Human1.06744694
121TP53_20018659_ChIP-ChIP_R1E_Mouse1.05773289
122STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.05616095
123AR_25329375_ChIP-Seq_VCAP_Human1.05395439
124RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.04428717
125ERG_20517297_ChIP-Seq_VCAP_Human1.04330032
126PRDM14_20953172_ChIP-Seq_ESCs_Human1.03315223
127TBL1_22424771_ChIP-Seq_293T_Human1.03127866
128MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.02271920
129KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.02256972
130AR_19668381_ChIP-Seq_PC3_Human1.01424832
131CDX2_22108803_ChIP-Seq_LS180_Human1.01416562
132ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.01273993
133PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.00704013
134RING1B_27294783_Chip-Seq_NPCs_Mouse0.99756310
135EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.99675692
136FOXM1_26456572_ChIP-Seq_MCF-7_Human0.99601541
137TAL1_26923725_Chip-Seq_HPCs_Mouse0.98899888
138FOXA1_21572438_ChIP-Seq_LNCaP_Human0.98445232
139CJUN_26792858_Chip-Seq_BT549_Human0.98319708
140TCF4_23295773_ChIP-Seq_U87_Human0.98070687
141IRF1_19129219_ChIP-ChIP_H3396_Human0.97973083
142IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.97640324
143CBP_20019798_ChIP-Seq_JUKART_Human0.97640324
144* WT1_25993318_ChIP-Seq_PODOCYTE_Human0.96873684
145PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.96691481
146SMAD3_21741376_ChIP-Seq_ESCs_Human0.96634696
147SMAD4_21741376_ChIP-Seq_HESCs_Human0.96583545
148TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.96027928
149JUN_21703547_ChIP-Seq_K562_Human0.95774152
150FOXM1_23109430_ChIP-Seq_U2OS_Human0.94787316
151NFYB_21822215_ChIP-Seq_K562_Human0.93906157
152PHF8_20622853_ChIP-Seq_HELA_Human0.93477490
153FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.92704656
154FLI1_27457419_Chip-Seq_LIVER_Mouse0.90024693
155NOTCH1_21737748_ChIP-Seq_TLL_Human0.88285718

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003136_yellow_coat_color6.34809618
2MP0002653_abnormal_ependyma_morphology5.63509165
3MP0005623_abnormal_meninges_morphology5.48139136
4MP0008877_abnormal_DNA_methylation3.52903828
5MP0005646_abnormal_pituitary_gland3.19403650
6MP0002132_abnormal_respiratory_system3.16968989
7MP0003718_maternal_effect3.15281980
8MP0005423_abnormal_somatic_nervous3.10160563
9MP0009046_muscle_twitch2.95120105
10MP0010094_abnormal_chromosome_stability2.70023260
11MP0008004_abnormal_stomach_pH2.68286801
12MP0003283_abnormal_digestive_organ2.64397845
13MP0004133_heterotaxia2.63385048
14MP0001986_abnormal_taste_sensitivity2.61875279
15MP0005451_abnormal_body_composition2.56587939
16MP0010030_abnormal_orbit_morphology2.54987459
17MP0004859_abnormal_synaptic_plasticity2.53101080
18MP0003890_abnormal_embryonic-extraembry2.46359172
19MP0001440_abnormal_grooming_behavior2.30721643
20MP0008057_abnormal_DNA_replication2.29958173
21MP0001929_abnormal_gametogenesis2.20346057
22MP0003690_abnormal_glial_cell2.16752228
23MP0005410_abnormal_fertilization2.15844177
24MP0004858_abnormal_nervous_system2.13777624
25MP0002095_abnormal_skin_pigmentation1.98746784
26MP0003195_calcinosis1.98532625
27MP0003880_abnormal_central_pattern1.89323237
28MP0009745_abnormal_behavioral_response1.84720550
29MP0002282_abnormal_trachea_morphology1.83322605
30MP0001501_abnormal_sleep_pattern1.82927303
31MP0002064_seizures1.79460821
32MP0002234_abnormal_pharynx_morphology1.78320550
33MP0000778_abnormal_nervous_system1.77114009
34MP0004043_abnormal_pH_regulation1.74789246
35MP0000462_abnormal_digestive_system1.73885317
36MP0002210_abnormal_sex_determination1.73317470
37MP0003635_abnormal_synaptic_transmissio1.71622170
38MP0001984_abnormal_olfaction1.63042839
39MP0002572_abnormal_emotion/affect_behav1.61754437
40MP0000428_abnormal_craniofacial_morphol1.58679335
41MP0005248_abnormal_Harderian_gland1.56339291
42MP0003634_abnormal_glial_cell1.53505240
43MP0003937_abnormal_limbs/digits/tail_de1.53002212
44MP0002272_abnormal_nervous_system1.52789490
45MP0008058_abnormal_DNA_repair1.51904955
46MP0000631_abnormal_neuroendocrine_gland1.51819056
47MP0002557_abnormal_social/conspecific_i1.44986609
48MP0005171_absent_coat_pigmentation1.44720296
49MP0003938_abnormal_ear_development1.43788620
50MP0003950_abnormal_plasma_membrane1.43371410
51MP0009250_abnormal_appendicular_skeleto1.43073685
52MP0000049_abnormal_middle_ear1.40401833
53MP0002063_abnormal_learning/memory/cond1.37720766
54MP0000653_abnormal_sex_gland1.35765905
55MP0005395_other_phenotype1.34642424
56MP0002876_abnormal_thyroid_physiology1.32656483
57MP0002133_abnormal_respiratory_system1.27534454
58MP0005388_respiratory_system_phenotype1.27534454
59MP0001177_atelectasis1.27037657
60MP0004142_abnormal_muscle_tone1.26205632
61MP0005075_abnormal_melanosome_morpholog1.26176583
62MP0002734_abnormal_mechanical_nocicepti1.25279928
63MP0002909_abnormal_adrenal_gland1.24103912
64MP0001145_abnormal_male_reproductive1.23721149
65MP0004381_abnormal_hair_follicle1.23470998
66MP0000383_abnormal_hair_follicle1.22817621
67MP0000372_irregular_coat_pigmentation1.22740700
68MP0001968_abnormal_touch/_nociception1.22333306
69MP0001324_abnormal_eye_pigmentation1.21164943
70MP0002249_abnormal_larynx_morphology1.19756008
71MP0006072_abnormal_retinal_apoptosis1.19748342
72MP0003646_muscle_fatigue1.18514310
73MP0002161_abnormal_fertility/fecundity1.18248902
74MP0005551_abnormal_eye_electrophysiolog1.18150879
75MP0000566_synostosis1.17442806
76MP0002735_abnormal_chemical_nociception1.14993852
77MP0002102_abnormal_ear_morphology1.11823696
78MP0001529_abnormal_vocalization1.11588674
79MP0010678_abnormal_skin_adnexa1.10404747
80MP0006292_abnormal_olfactory_placode1.09614601
81MP0004270_analgesia1.08904229
82MP0002160_abnormal_reproductive_system1.08698192
83MP0001486_abnormal_startle_reflex1.07000865
84MP0003693_abnormal_embryo_hatching1.06349771
85MP0001293_anophthalmia1.05137492
86MP0003122_maternal_imprinting1.04269982
87MP0005174_abnormal_tail_pigmentation1.03509301
88MP0002152_abnormal_brain_morphology1.03465014
89MP0002736_abnormal_nociception_after1.03249480
90MP0003567_abnormal_fetal_cardiomyocyte1.02853158
91MP0003878_abnormal_ear_physiology1.02557419
92MP0005377_hearing/vestibular/ear_phenot1.02557419
93MP0003077_abnormal_cell_cycle1.00566162
94MP0003633_abnormal_nervous_system0.97574130
95MP0001944_abnormal_pancreas_morphology0.96855611
96MP0003183_abnormal_peptide_metabolism0.96749971
97MP0003121_genomic_imprinting0.96089058
98MP0002638_abnormal_pupillary_reflex0.95223162
99MP0002067_abnormal_sensory_capabilities0.94711477
100MP0000015_abnormal_ear_pigmentation0.94498422
101MP0005084_abnormal_gallbladder_morpholo0.93473758
102MP0009384_cardiac_valve_regurgitation0.93409698
103MP0008995_early_reproductive_senescence0.93366349
104MP0000427_abnormal_hair_cycle0.93014497
105MP0003699_abnormal_female_reproductive0.91928053
106MP0002938_white_spotting0.90692615
107MP0000013_abnormal_adipose_tissue0.90453944
108MP0009379_abnormal_foot_pigmentation0.90190866
109MP0002928_abnormal_bile_duct0.89486669
110MP0000516_abnormal_urinary_system0.88775342
111MP0005367_renal/urinary_system_phenotyp0.88775342
112MP0002882_abnormal_neuron_morphology0.88726167
113MP0001663_abnormal_digestive_system0.88710552
114MP0005167_abnormal_blood-brain_barrier0.88617037
115MP0009278_abnormal_bone_marrow0.87043312
116MP0000647_abnormal_sebaceous_gland0.86669302
117MP0001958_emphysema0.86137646
118MP0003252_abnormal_bile_duct0.85499990
119MP0009697_abnormal_copulation0.85058370
120MP0008569_lethality_at_weaning0.84341552
121MP0003861_abnormal_nervous_system0.83906032
122MP0000955_abnormal_spinal_cord0.83884828
123MP0005220_abnormal_exocrine_pancreas0.83553196
124MP0002168_other_aberrant_phenotype0.83517352
125MP0005391_vision/eye_phenotype0.83012466
126MP0009780_abnormal_chondrocyte_physiolo0.82823677
127MP0003942_abnormal_urinary_system0.80461061
128MP0001943_abnormal_respiration0.80441154
129MP0004084_abnormal_cardiac_muscle0.80284132
130MP0006276_abnormal_autonomic_nervous0.78692068
131MP0000569_abnormal_digit_pigmentation0.78048122
132MP0002127_abnormal_cardiovascular_syste0.77736642
133MP0001970_abnormal_pain_threshold0.77448953
134MP0001851_eye_inflammation0.76921385
135MP0001270_distended_abdomen0.76741582
136MP0006036_abnormal_mitochondrial_physio0.75751224
137MP0005381_digestive/alimentary_phenotyp0.75644420
138MP0008789_abnormal_olfactory_epithelium0.75434044
139MP0002166_altered_tumor_susceptibility0.75104001
140MP0001485_abnormal_pinna_reflex0.74649796
141MP0002837_dystrophic_cardiac_calcinosis0.73403638
142MP0002116_abnormal_craniofacial_bone0.73296574
143MP0005394_taste/olfaction_phenotype0.72180619
144MP0005499_abnormal_olfactory_system0.72180619
145MP0003137_abnormal_impulse_conducting0.71181666
146MP0005389_reproductive_system_phenotype0.70822197
147MP0004742_abnormal_vestibular_system0.70667230
148MP0002084_abnormal_developmental_patter0.70231281
149MP0002752_abnormal_somatic_nervous0.69867406
150MP0004145_abnormal_muscle_electrophysio0.69321640
151MP0002896_abnormal_bone_mineralization0.68684455
152MP0001765_abnormal_ion_homeostasis0.68681056
153MP0008875_abnormal_xenobiotic_pharmacok0.68037826
154MP0004885_abnormal_endolymph0.67659491
155MP0000026_abnormal_inner_ear0.67350085
156MP0000470_abnormal_stomach_morphology0.67190759
157MP0002254_reproductive_system_inflammat0.67080672
158MP0003385_abnormal_body_wall0.67036623
159MP0002066_abnormal_motor_capabilities/c0.66934790
160MP0001879_abnormal_lymphatic_vessel0.66841058
161MP0005253_abnormal_eye_physiology0.66734792
162MP0004085_abnormal_heartbeat0.66423055
163MP0001905_abnormal_dopamine_level0.66237317
164MP0002184_abnormal_innervation0.65503062
165MP0000432_abnormal_head_morphology0.63731383
166MP0000749_muscle_degeneration0.63725322
167MP0003329_amyloid_beta_deposits0.63588386
168MP0005195_abnormal_posterior_eye0.62789747
169MP0003698_abnormal_male_reproductive0.62398718
170MP0002233_abnormal_nose_morphology0.62197917

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory epithelium morphology (HP:0012253)9.47191101
2Abnormal respiratory motile cilium morphology (HP:0005938)9.47191101
3B lymphocytopenia (HP:0010976)8.88564105
4Abnormality of B cell number (HP:0010975)7.64468694
5Hypoplasia of the thymus (HP:0000778)7.03732997
6Thyroiditis (HP:0100646)6.16171835
7Bronchiectasis (HP:0002110)6.12461217
8Severe combined immunodeficiency (HP:0004430)6.10652586
9Hypoproteinemia (HP:0003075)5.86613367
10Absent/shortened dynein arms (HP:0200106)5.85647898
11Dynein arm defect of respiratory motile cilia (HP:0012255)5.85647898
12Panhypogammaglobulinemia (HP:0003139)5.46137187
13Combined immunodeficiency (HP:0005387)5.17517453
14Chronic bronchitis (HP:0004469)4.92305005
15Pancreatic fibrosis (HP:0100732)4.74012448
16Chronic sinusitis (HP:0011109)4.63871448
17Recurrent sinusitis (HP:0011108)4.15321166
18Esophageal neoplasm (HP:0100751)4.11003341
19Neoplasm of head and neck (HP:0012288)4.11003341
20Nasal polyposis (HP:0100582)3.97176754
21Erythroderma (HP:0001019)3.81226528
22True hermaphroditism (HP:0010459)3.73463188
23Abnormality of the nasal mucosa (HP:0000433)3.29639843
24Median cleft lip (HP:0000161)3.25922998
25Eosinophilia (HP:0001880)3.21453145
26Medial flaring of the eyebrow (HP:0010747)3.10854536
27Gait imbalance (HP:0002141)3.08436213
28Concave nail (HP:0001598)3.07515808
29Bronchitis (HP:0012387)3.07358497
30Methylmalonic acidemia (HP:0002912)3.02756701
31Congenital primary aphakia (HP:0007707)2.98898961
32Nephronophthisis (HP:0000090)2.86765751
33Genital tract atresia (HP:0001827)2.68969599
34Aplasia/Hypoplasia of the tongue (HP:0010295)2.68182497
35Nephrogenic diabetes insipidus (HP:0009806)2.67617749
36Occipital encephalocele (HP:0002085)2.65783254
37T lymphocytopenia (HP:0005403)2.65738273
38Pancreatic cysts (HP:0001737)2.61420292
39Type II lissencephaly (HP:0007260)2.60233663
40Retinal dysplasia (HP:0007973)2.56743661
41Postaxial foot polydactyly (HP:0001830)2.55589838
42Metaphyseal dysplasia (HP:0100255)2.52285197
43Oligodactyly (hands) (HP:0001180)2.51063460
44Congenital hepatic fibrosis (HP:0002612)2.47594357
45Abnormality of midbrain morphology (HP:0002418)2.45558849
46Molar tooth sign on MRI (HP:0002419)2.45558849
47Abnormality of eosinophils (HP:0001879)2.43426123
48Abnormality of dentin (HP:0010299)2.41526369
49Cystic liver disease (HP:0006706)2.38613821
50Bile duct proliferation (HP:0001408)2.37496914
51Abnormal biliary tract physiology (HP:0012439)2.37496914
52Hypoglycemic coma (HP:0001325)2.36316966
53Granulocytopenia (HP:0001913)2.32806737
54Abnormality of the labia minora (HP:0012880)2.29605846
55Hyperglycinemia (HP:0002154)2.28345050
56Infertility (HP:0000789)2.26189779
57Hypoglycemic seizures (HP:0002173)2.19931132
58Recurrent otitis media (HP:0000403)2.18841920
59Abnormality of the renal medulla (HP:0100957)2.18657246
60Hyperinsulinemic hypoglycemia (HP:0000825)2.18200103
61Ketoacidosis (HP:0001993)2.17007214
62Back pain (HP:0003418)2.16400087
63Facial hemangioma (HP:0000329)2.15027541
64Abnormal pancreas size (HP:0012094)2.13877875
65Abnormality of vitamin B metabolism (HP:0004340)2.12997771
66Vaginal atresia (HP:0000148)2.12662656
67Poor coordination (HP:0002370)2.09688628
68Gonadotropin excess (HP:0000837)2.07681308
69Abnormality of the vitamin B12 metabolism (HP:0004341)2.06240734
70Abnormal ciliary motility (HP:0012262)14.6695579
71Abnormal respiratory motile cilium physiology (HP:0012261)13.4219233
72Respiratory insufficiency due to defective ciliary clearance (HP:0200073)11.0751544
73Rhinitis (HP:0012384)10.9820027
74Microglossia (HP:0000171)1.97779422
75Preaxial hand polydactyly (HP:0001177)1.93342106
76Attenuation of retinal blood vessels (HP:0007843)1.91837565
77Tubulointerstitial nephritis (HP:0001970)1.91225361
78Abnormality of T cell number (HP:0011839)1.90704754
79Fibular hypoplasia (HP:0003038)1.89098835
80Postaxial hand polydactyly (HP:0001162)1.88947114
81Stage 5 chronic kidney disease (HP:0003774)1.87455071
82Recurrent bronchitis (HP:0002837)1.84060826
83Lower limb hyperreflexia (HP:0002395)1.83112942
84Volvulus (HP:0002580)1.80660769
85Methylmalonic aciduria (HP:0012120)1.80117503
86Anencephaly (HP:0002323)1.78317812
87Aplasia/Hypoplasia of the lens (HP:0008063)1.76886345
88Oligodactyly (HP:0012165)1.76363962
89Tubular atrophy (HP:0000092)1.74753899
90Aplasia/Hypoplasia of the thymus (HP:0010515)1.74246679
91Cerebellar dysplasia (HP:0007033)1.74029123
92Chromsome breakage (HP:0040012)1.72617050
93Supernumerary spleens (HP:0009799)1.71968206
94Abnormality of the metopic suture (HP:0005556)1.70865222
95Sclerocornea (HP:0000647)1.68239858
96Male pseudohermaphroditism (HP:0000037)1.67450594
97Chronic hepatic failure (HP:0100626)1.66128742
98Congenital sensorineural hearing impairment (HP:0008527)1.65602244
99Abnormal umbilical cord blood vessels (HP:0011403)1.65158648
100Single umbilical artery (HP:0001195)1.65158648
101Abnormality of the fetal cardiovascular system (HP:0010948)1.65158648
102IgG deficiency (HP:0004315)1.64630328
103Abnormality of permanent molar morphology (HP:0011071)1.63798522
104Abnormality of the dental root (HP:0006486)1.63798522
105Taurodontia (HP:0000679)1.63798522
106Abnormality of the septum pellucidum (HP:0007375)1.61630572
107Abnormality of the pancreatic islet cells (HP:0006476)1.60559615
108Abnormality of endocrine pancreas physiology (HP:0012093)1.60559615
109Decreased central vision (HP:0007663)1.60480409
110Short tibia (HP:0005736)1.60376985
111Aplasia/Hypoplasia of the uvula (HP:0010293)1.59926187
112Abnormality of chromosome stability (HP:0003220)1.59793476
113Large for gestational age (HP:0001520)1.59390438
114Sex reversal (HP:0012245)1.59163977
115Abnormal sex determination (HP:0012244)1.59163977
116Prominent metopic ridge (HP:0005487)1.58548911
117Papillary thyroid carcinoma (HP:0002895)1.58468066
118Abnormality of lateral ventricle (HP:0030047)1.58314946
119Ridged nail (HP:0001807)1.58134078
120Absent septum pellucidum (HP:0001331)1.57513901
121Hypodontia (HP:0000668)1.57078980
122Shoulder girdle muscle weakness (HP:0003547)1.56874609
123Aplasia/Hypoplasia of the tibia (HP:0005772)1.56688012
124Focal motor seizures (HP:0011153)1.56668057
125Abnormal lung lobation (HP:0002101)1.55711239
126Horizontal nystagmus (HP:0000666)1.54765387
127Bifid tongue (HP:0010297)1.54275864
128Specific learning disability (HP:0001328)1.53836267
129Abdominal situs inversus (HP:0003363)1.52137643
130Abnormality of abdominal situs (HP:0011620)1.52137643
131Abnormality of the dental pulp (HP:0006479)1.51488400
132Tubulointerstitial abnormality (HP:0001969)1.51201627
133Abnormality of macular pigmentation (HP:0008002)1.50174966
134Abnormality of molar morphology (HP:0011070)1.48975583
135Abnormality of molar (HP:0011077)1.48975583
136Truncal obesity (HP:0001956)1.48006684
137Prominent nasal bridge (HP:0000426)1.47986205
138Atelectasis (HP:0100750)1.45964585
139Bronchomalacia (HP:0002780)1.42966924
140Oculomotor apraxia (HP:0000657)1.42207149
141Furrowed tongue (HP:0000221)1.41212482
142Polycystic kidney dysplasia (HP:0000113)1.39843587
143Hypotelorism (HP:0000601)1.39508284
144Male infertility (HP:0003251)1.38208406
145Short nail (HP:0001799)1.36910084
146Neonatal short-limb short stature (HP:0008921)1.34391110
147Ectopic anus (HP:0004397)1.34119570
148Hyperactive renin-angiotensin system (HP:0000841)1.32604038
149Polycystic ovaries (HP:0000147)1.30540294
150Facial cleft (HP:0002006)1.27157817
151Broad foot (HP:0001769)1.26380154
152Asplenia (HP:0001746)1.25619558
153Onycholysis (HP:0001806)1.25594594
154Papilledema (HP:0001085)1.24184012
155Metabolic alkalosis (HP:0200114)1.22295621
156Tubulointerstitial fibrosis (HP:0005576)1.18539233

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPK159.69947289
2PNCK5.57654394
3TRIM283.85312166
4PRKD33.44356555
5NTRK23.39170060
6EIF2AK33.27663034
7MET2.67931865
8SIK12.54035412
9MKNK22.51648674
10SRPK12.45111524
11STK38L2.29149405
12BMPR1B2.16069066
13FRK2.11038205
14PLK41.99990437
15PINK11.85906158
16DAPK21.85395233
17CASK1.77895387
18NTRK31.70419929
19TSSK61.66042404
20TTK1.65382265
21FGR1.63461644
22NEK11.57632103
23MAP3K41.49538349
24MAP2K71.48495495
25BRSK21.46092111
26MARK11.41928659
27GRK11.40718706
28DMPK1.37301115
29EPHA31.36015045
30NUAK11.35062119
31RPS6KA41.29808676
32ITK1.27806080
33EPHA41.24479081
34ZAK1.22258290
35FES1.21889616
36MAP2K41.21727668
37SIK21.20158996
38MKNK11.16465145
39PASK1.15718916
40WNK31.15365342
41ACVR1B1.15323008
42CSK1.14910494
43PLK31.13720999
44CDK81.13510744
45MST41.13471918
46PLK11.11216813
47PTK2B1.08672368
48LMTK21.07444689
49MAPK121.06215245
50GRK51.05842204
51PAK21.05657106
52TNIK1.04790130
53TGFBR11.04326852
54NLK1.03113456
55OBSCN1.02080530
56ROCK21.00439620
57MAP3K90.99389068
58RPS6KB10.98642480
59PTK20.96326240
60PRKCG0.93619256
61CDK90.92846244
62VRK10.91619920
63NEK60.91237101
64MUSK0.89279111
65WEE10.89064061
66CDK30.88082344
67GSK3A0.87466846
68MINK10.87434844
69CSNK1G10.87215514
70CAMK2A0.87132755
71CCNB10.86665625
72STK30.85973362
73NME10.82394997
74PKN10.78881055
75FER0.75501101
76PRKD20.73455857
77PBK0.73353002
78STK240.73013922
79MAP4K20.70844041
80ATR0.70530561
81BRD40.70179296
82CAMKK10.69047812
83TEC0.68616504
84CDC42BPA0.68496063
85CAMK2B0.68352489
86CDK70.68330892
87CDK50.67728449
88VRK20.67384039
89ATM0.66865421
90PRKG10.63747707
91PHKG20.63269597
92PHKG10.63269597
93LATS10.62400531
94DYRK1A0.62104061
95CSNK1G20.62029110
96EIF2AK10.61599324
97ARAF0.60296712
98MAPK130.60181763
99KSR10.59872507
100ERBB30.59744220
101PAK30.59294835
102BCR0.58335266
103TRPM70.58257596
104STK380.58034405
105SRC0.57389296
106CSNK1G30.57084675
107UHMK10.56875500
108FLT30.56813408
109MAP3K20.55623744
110PRKCE0.55252560
111PRKCI0.55050810
112BUB10.54429687
113NTRK10.54232606
114BLK0.53214575
115PRKAA20.51480077
116MAP3K70.51422402
117SGK2230.49837406
118SGK4940.49837406
119PRKACA0.49690316
120FGFR20.49562362
121CAMK2D0.49052102
122ROCK10.48980460
123PAK60.47637124
124PRKACB0.47444239
125BRSK10.47209069
126RPS6KA20.47145286
127AURKA0.47058709
128DYRK1B0.45931895
129RIPK40.45859625
130PLK20.45630969
131OXSR10.45406581
132TAF10.44148083
133BMPR20.43238906
134CSNK1D0.43179382
135CSNK1E0.42518081
136PRKACG0.42119180
137CHEK10.41710279
138TNK20.41586266
139FYN0.41193594
140INSRR0.41015517
141INSR0.40333434
142PRKCH0.39555798
143CDK20.39555290
144HIPK20.39502749
145ADRBK20.38522986
146CAMK2G0.37107131
147DDR20.36155883
148DYRK20.35761025
149CAMK10.35439347
150PDGFRA0.34970776
151GRK60.34902843
152AKT20.33983374
153RPS6KA30.33892492
154MAP3K130.33031337
155YES10.33014624
156CAMKK20.32303994
157CDK140.32270452
158LIMK10.31562540
159IGF1R0.31009262
160TIE10.29436337
161MAPK100.29154259
162MOS0.28517196
163PRKCA0.27796714
164SGK20.27157745
165STK390.27154516
166PRKDC0.26969485

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000726.56839688
2Non-homologous end-joining_Homo sapiens_hsa034505.04229403
3Huntingtons disease_Homo sapiens_hsa050162.95860603
4Basal transcription factors_Homo sapiens_hsa030222.80091943
5Butanoate metabolism_Homo sapiens_hsa006502.77845823
6Mismatch repair_Homo sapiens_hsa034302.60351278
7Maturity onset diabetes of the young_Homo sapiens_hsa049502.58826772
8Fanconi anemia pathway_Homo sapiens_hsa034602.51511065
9Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.50200794
10Nicotine addiction_Homo sapiens_hsa050332.48468422
11Homologous recombination_Homo sapiens_hsa034402.21297361
12Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.19154661
13GABAergic synapse_Homo sapiens_hsa047272.18897303
14Nucleotide excision repair_Homo sapiens_hsa034201.92102544
15Taste transduction_Homo sapiens_hsa047421.90696799
16Cell cycle_Homo sapiens_hsa041101.89171980
17RNA degradation_Homo sapiens_hsa030181.85744799
18Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.81443428
19Glutamatergic synapse_Homo sapiens_hsa047241.79516472
20Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.78487111
21Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.69388636
22RNA transport_Homo sapiens_hsa030131.68437392
23Caffeine metabolism_Homo sapiens_hsa002321.62961812
24RNA polymerase_Homo sapiens_hsa030201.58242782
25DNA replication_Homo sapiens_hsa030301.53415437
26Circadian entrainment_Homo sapiens_hsa047131.50927644
27Gastric acid secretion_Homo sapiens_hsa049711.48888195
28Ether lipid metabolism_Homo sapiens_hsa005651.46910666
29Oocyte meiosis_Homo sapiens_hsa041141.44879737
30Olfactory transduction_Homo sapiens_hsa047401.44728551
31Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.43627274
32Amphetamine addiction_Homo sapiens_hsa050311.41685841
33Phototransduction_Homo sapiens_hsa047441.39900348
34Calcium signaling pathway_Homo sapiens_hsa040201.38861602
35Insulin secretion_Homo sapiens_hsa049111.38196003
36Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.34777882
37Primary immunodeficiency_Homo sapiens_hsa053401.32373298
38Oxidative phosphorylation_Homo sapiens_hsa001901.30392161
39Circadian rhythm_Homo sapiens_hsa047101.24857331
40Morphine addiction_Homo sapiens_hsa050321.24290158
41Nitrogen metabolism_Homo sapiens_hsa009101.23823161
42Dopaminergic synapse_Homo sapiens_hsa047281.22659790
43Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.22164367
44Base excision repair_Homo sapiens_hsa034101.21372239
45Cardiac muscle contraction_Homo sapiens_hsa042601.21151629
46Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.20306796
47mRNA surveillance pathway_Homo sapiens_hsa030151.20218651
48Folate biosynthesis_Homo sapiens_hsa007901.20160181
49Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.19794679
50Dorso-ventral axis formation_Homo sapiens_hsa043201.17615039
51Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.15463506
52Sulfur metabolism_Homo sapiens_hsa009201.14517845
53Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.13742829
54Steroid biosynthesis_Homo sapiens_hsa001001.12733252
55Long-term depression_Homo sapiens_hsa047301.12577145
56Alzheimers disease_Homo sapiens_hsa050101.09354284
57Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.05882400
58Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.05393725
59Ovarian steroidogenesis_Homo sapiens_hsa049131.05271072
60GnRH signaling pathway_Homo sapiens_hsa049121.04749577
61Cysteine and methionine metabolism_Homo sapiens_hsa002701.04307259
62Serotonergic synapse_Homo sapiens_hsa047261.04137803
63Purine metabolism_Homo sapiens_hsa002301.03947047
64Thyroid hormone synthesis_Homo sapiens_hsa049181.03355429
65Long-term potentiation_Homo sapiens_hsa047201.02662047
66Cocaine addiction_Homo sapiens_hsa050301.02619500
67Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.01962470
68Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.01537702
69Salivary secretion_Homo sapiens_hsa049701.01454006
70Regulation of autophagy_Homo sapiens_hsa041401.00140377
71Fatty acid elongation_Homo sapiens_hsa000620.98376313
72Vascular smooth muscle contraction_Homo sapiens_hsa042700.97430047
73Renin secretion_Homo sapiens_hsa049240.97423137
74Bile secretion_Homo sapiens_hsa049760.96771080
75PPAR signaling pathway_Homo sapiens_hsa033200.95526021
76Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.93207117
77Axon guidance_Homo sapiens_hsa043600.90351205
78Melanogenesis_Homo sapiens_hsa049160.89571588
79Parkinsons disease_Homo sapiens_hsa050120.89517789
80Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.87689458
81Primary bile acid biosynthesis_Homo sapiens_hsa001200.87674004
82Basal cell carcinoma_Homo sapiens_hsa052170.86699158
83Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.86237830
84alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.85276144
85Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.83951813
86Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.83156773
87Oxytocin signaling pathway_Homo sapiens_hsa049210.83014568
88Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.82385963
89cAMP signaling pathway_Homo sapiens_hsa040240.81590774
90Aldosterone synthesis and secretion_Homo sapiens_hsa049250.80545255
91Estrogen signaling pathway_Homo sapiens_hsa049150.78985761
92Fatty acid metabolism_Homo sapiens_hsa012120.78491952
93Mineral absorption_Homo sapiens_hsa049780.78237970
94Wnt signaling pathway_Homo sapiens_hsa043100.77423485
95Arginine and proline metabolism_Homo sapiens_hsa003300.77039316
96Proteasome_Homo sapiens_hsa030500.74953490
97Pyruvate metabolism_Homo sapiens_hsa006200.74435867
98cGMP-PKG signaling pathway_Homo sapiens_hsa040220.72487643
99Cholinergic synapse_Homo sapiens_hsa047250.72384741
100beta-Alanine metabolism_Homo sapiens_hsa004100.71381571
101Hedgehog signaling pathway_Homo sapiens_hsa043400.70612812
102FoxO signaling pathway_Homo sapiens_hsa040680.70188074
103Dilated cardiomyopathy_Homo sapiens_hsa054140.69013424
104Phenylalanine metabolism_Homo sapiens_hsa003600.68913032
105Glutathione metabolism_Homo sapiens_hsa004800.67637271
106Tyrosine metabolism_Homo sapiens_hsa003500.66817396
107Propanoate metabolism_Homo sapiens_hsa006400.66110232
108Pancreatic secretion_Homo sapiens_hsa049720.65821074
109Synaptic vesicle cycle_Homo sapiens_hsa047210.65554258
110Metabolic pathways_Homo sapiens_hsa011000.65521829
111Carbohydrate digestion and absorption_Homo sapiens_hsa049730.65292398
112ABC transporters_Homo sapiens_hsa020100.65076884
113Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.64474168
114Prion diseases_Homo sapiens_hsa050200.63378819
115mTOR signaling pathway_Homo sapiens_hsa041500.63371811
116Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.62249390
117Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.61496828
118Type II diabetes mellitus_Homo sapiens_hsa049300.61146117
119Gap junction_Homo sapiens_hsa045400.59880131
120Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.59676551
121Complement and coagulation cascades_Homo sapiens_hsa046100.59190046
122Fatty acid degradation_Homo sapiens_hsa000710.57059067
123Vitamin B6 metabolism_Homo sapiens_hsa007500.56120977
124Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.55165037
125p53 signaling pathway_Homo sapiens_hsa041150.54962899
126Fatty acid biosynthesis_Homo sapiens_hsa000610.53159367
127Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.51135541
128Spliceosome_Homo sapiens_hsa030400.50053775
129Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.49622067
130Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.49502785
131Sphingolipid metabolism_Homo sapiens_hsa006000.48461669
132Hippo signaling pathway_Homo sapiens_hsa043900.47743084
133Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.47561533
134Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.45472657
135Peroxisome_Homo sapiens_hsa041460.45313014
136Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.44862911
137Selenocompound metabolism_Homo sapiens_hsa004500.44141376
138Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.43389985
139TGF-beta signaling pathway_Homo sapiens_hsa043500.41867569
140Glycerophospholipid metabolism_Homo sapiens_hsa005640.41792298
141Arachidonic acid metabolism_Homo sapiens_hsa005900.40493872
142Collecting duct acid secretion_Homo sapiens_hsa049660.40033416
143Pyrimidine metabolism_Homo sapiens_hsa002400.39408691
144Protein export_Homo sapiens_hsa030600.38986107
145Renal cell carcinoma_Homo sapiens_hsa052110.38189458
146Linoleic acid metabolism_Homo sapiens_hsa005910.37529605
147Choline metabolism in cancer_Homo sapiens_hsa052310.37256876
148Inositol phosphate metabolism_Homo sapiens_hsa005620.35154066
149Histidine metabolism_Homo sapiens_hsa003400.34711824
150Insulin resistance_Homo sapiens_hsa049310.34517567
151Chemical carcinogenesis_Homo sapiens_hsa052040.34406862
152Phosphatidylinositol signaling system_Homo sapiens_hsa040700.33062541
153Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.33021979
154N-Glycan biosynthesis_Homo sapiens_hsa005100.32169189

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