CCDC124

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of mitochondrial translation (GO:0070129)6.26573034
2arginine catabolic process (GO:0006527)6.08068864
3protein maturation by protein folding (GO:0022417)5.59922196
4proteasome assembly (GO:0043248)5.17467274
5DNA deamination (GO:0045006)5.11369657
6mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.03716999
7deoxyribonucleoside monophosphate metabolic process (GO:0009162)4.89195907
8negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.88888308
9mitochondrial fusion (GO:0008053)4.81414908
10negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)4.75234860
11mitotic nuclear envelope reassembly (GO:0007084)4.61785953
12nuclear envelope reassembly (GO:0031468)4.61785953
13positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)4.57955334
147-methylguanosine mRNA capping (GO:0006370)4.53179573
15energy coupled proton transport, down electrochemical gradient (GO:0015985)4.48494890
16ATP synthesis coupled proton transport (GO:0015986)4.48494890
17regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)4.44773222
18formation of translation preinitiation complex (GO:0001731)4.44334570
19anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:04.44174281
20negative regulation of ubiquitin-protein transferase activity (GO:0051444)4.39943326
21negative regulation of ligase activity (GO:0051352)4.39943326
22viral transcription (GO:0019083)4.39704970
23establishment of protein localization to mitochondrial membrane (GO:0090151)4.33963693
24translational termination (GO:0006415)4.33005830
257-methylguanosine RNA capping (GO:0009452)4.32974160
26RNA capping (GO:0036260)4.32974160
27GDP-mannose metabolic process (GO:0019673)4.26254112
28peptidyl-arginine omega-N-methylation (GO:0035247)4.26046271
29positive regulation of ubiquitin-protein transferase activity (GO:0051443)4.20906878
30DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:004.16420711
31establishment of integrated proviral latency (GO:0075713)4.16179249
32DNA replication checkpoint (GO:0000076)4.11714860
33signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)4.07602756
34signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)4.07602756
35signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)4.07602756
36intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)4.06230382
37signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)4.06230382
38inner mitochondrial membrane organization (GO:0007007)4.06003986
39establishment of viral latency (GO:0019043)4.00096084
40positive regulation of ligase activity (GO:0051351)3.99889702
41signal transduction involved in DNA integrity checkpoint (GO:0072401)3.98527995
42signal transduction involved in DNA damage checkpoint (GO:0072422)3.98527995
43translational initiation (GO:0006413)3.97780425
44purine nucleobase biosynthetic process (GO:0009113)3.96103356
45regulation of cellular amino acid metabolic process (GO:0006521)3.95800132
46histone arginine methylation (GO:0034969)3.94489536
47signal transduction involved in cell cycle checkpoint (GO:0072395)3.94419252
48spliceosomal snRNP assembly (GO:0000387)3.94278046
49protein neddylation (GO:0045116)3.94270009
50translational elongation (GO:0006414)3.93611725
51DNA strand elongation involved in DNA replication (GO:0006271)3.87259500
52sequestering of actin monomers (GO:0042989)3.87107711
53proline biosynthetic process (GO:0006561)3.87025702
54antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.86984453
55ribosomal small subunit biogenesis (GO:0042274)3.86120251
56termination of RNA polymerase III transcription (GO:0006386)3.82384982
57transcription elongation from RNA polymerase III promoter (GO:0006385)3.82384982
58COPI coating of Golgi vesicle (GO:0048205)3.78656389
59Golgi transport vesicle coating (GO:0048200)3.78656389
60nucleobase biosynthetic process (GO:0046112)3.78634376
61maturation of SSU-rRNA (GO:0030490)3.78334354
62translation (GO:0006412)3.77268583
63establishment of protein localization to mitochondrion (GO:0072655)3.76902249
64ribosomal large subunit biogenesis (GO:0042273)3.75055355
65protein targeting to mitochondrion (GO:0006626)3.75027215
66cullin deneddylation (GO:0010388)3.71493238
67cellular protein complex disassembly (GO:0043624)3.64379686
68protein deneddylation (GO:0000338)3.63628845
69antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.62864939
70negative regulation of release of cytochrome c from mitochondria (GO:0090201)3.62796260
71positive regulation of cell cycle arrest (GO:0071158)3.62445348
72regulation of ubiquitin-protein transferase activity (GO:0051438)3.61921075
73pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.61311231
74DNA strand elongation (GO:0022616)3.60500618
75regulation of oxidative phosphorylation (GO:0002082)3.60294208
76nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.58648905
77ribonucleoprotein complex biogenesis (GO:0022613)3.58513078
78SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.57738870
79ribosome biogenesis (GO:0042254)3.57233031
80regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022353.53514141
81protein complex biogenesis (GO:0070271)3.52580853
82UTP biosynthetic process (GO:0006228)3.52545018
83mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.52036075
84cotranslational protein targeting to membrane (GO:0006613)3.50934844
85protein targeting to ER (GO:0045047)3.50515711
86cytochrome complex assembly (GO:0017004)3.49263202
87chaperone-mediated protein transport (GO:0072321)3.49197417
88guanosine-containing compound biosynthetic process (GO:1901070)3.48984757
89protein localization to mitochondrion (GO:0070585)3.47809346
90regulation of ligase activity (GO:0051340)3.46858653
91viral life cycle (GO:0019058)3.46272229
92pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.44090564
93telomere maintenance via semi-conservative replication (GO:0032201)3.43697565
94nitric oxide biosynthetic process (GO:0006809)3.42817661
95ribosomal small subunit assembly (GO:0000028)3.42616063
96respiratory electron transport chain (GO:0022904)3.41194762
97ribosome assembly (GO:0042255)3.40097556
98rRNA modification (GO:0000154)3.39335280
99mitochondrial respiratory chain complex assembly (GO:0033108)3.38366748
100cellular component biogenesis (GO:0044085)3.37690682
101peptidyl-arginine methylation (GO:0018216)3.37321647
102peptidyl-arginine N-methylation (GO:0035246)3.37321647
103nucleobase-containing small molecule interconversion (GO:0015949)3.35959614
104GTP biosynthetic process (GO:0006183)3.35398366
105oxidative phosphorylation (GO:0006119)3.35322332
106regulation of translational termination (GO:0006449)3.34026704
107protein localization to endoplasmic reticulum (GO:0070972)3.34026081
108iron-sulfur cluster assembly (GO:0016226)3.33894618
109metallo-sulfur cluster assembly (GO:0031163)3.33894618
110pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.33176868
111electron transport chain (GO:0022900)3.32427397
112regulation of ruffle assembly (GO:1900027)3.32059537
113pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.30863812
114citrulline metabolic process (GO:0000052)3.29839614
115DNA damage response, detection of DNA damage (GO:0042769)3.29826810
116L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.29612523
117establishment of protein localization to endoplasmic reticulum (GO:0072599)3.28460675
118regulation of mammary gland epithelial cell proliferation (GO:0033599)3.27302625
119arginine metabolic process (GO:0006525)3.24817712
120protein retention in ER lumen (GO:0006621)3.23798613
121pseudouridine synthesis (GO:0001522)3.21955600
122CTP biosynthetic process (GO:0006241)3.19934046
123CTP metabolic process (GO:0046036)3.19934046
124base-excision repair, AP site formation (GO:0006285)3.18548576
125transcription from mitochondrial promoter (GO:0006390)3.18208407
126rRNA processing (GO:0006364)3.18033156
1272-deoxyribonucleotide biosynthetic process (GO:0009265)3.17654138
128deoxyribose phosphate biosynthetic process (GO:0046385)3.17654138
129transcription from RNA polymerase I promoter (GO:0006360)3.16190762
130protein complex disassembly (GO:0043241)3.15516127
131G1/S transition of mitotic cell cycle (GO:0000082)3.15003031
132UTP metabolic process (GO:0046051)3.12846580
133maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.10031382
134negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.09263605
135pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)3.04944764
136regulation of translational fidelity (GO:0006450)3.04784797
137spliceosomal tri-snRNP complex assembly (GO:0000244)3.01864087
138pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.00510676
139lipopolysaccharide biosynthetic process (GO:0009103)2.98086622
140DNA unwinding involved in DNA replication (GO:0006268)2.96179520
141protein insertion into membrane (GO:0051205)2.92916489
142pentose-phosphate shunt (GO:0006098)2.91371716
143transcription-coupled nucleotide-excision repair (GO:0006283)2.91334559
144negative regulation of DNA-templated transcription, elongation (GO:0032785)2.87822695
145UV protection (GO:0009650)2.86418515
146base-excision repair (GO:0006284)2.85093336
147pentose metabolic process (GO:0019321)2.83274963

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat6.81236107
2EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.23801634
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.99997583
4E2F7_22180533_ChIP-Seq_HELA_Human3.73174740
5* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.73144074
6KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.59680399
7* ETS1_20019798_ChIP-Seq_JURKAT_Human3.49658926
8SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.45092414
9GABP_17652178_ChIP-ChIP_JURKAT_Human3.30788091
10EST1_17652178_ChIP-ChIP_JURKAT_Human3.12256440
11MYC_18358816_ChIP-ChIP_MESCs_Mouse3.01638253
12* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.84759253
13NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.80380316
14CREB1_15753290_ChIP-ChIP_HEK293T_Human2.80128745
15* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.73244912
16CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.44619230
17XRN2_22483619_ChIP-Seq_HELA_Human2.40325701
18HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.24859189
19DCP1A_22483619_ChIP-Seq_HELA_Human2.10903642
20* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.06855890
21HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.06704530
22* YY1_21170310_ChIP-Seq_MESCs_Mouse2.06581476
23CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.06548085
24* VDR_23849224_ChIP-Seq_CD4+_Human2.05109023
25MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.02518709
26FOXM1_23109430_ChIP-Seq_U2OS_Human2.01281665
27POU5F1_18555785_ChIP-Seq_MESCs_Mouse2.01278944
28THAP11_20581084_ChIP-Seq_MESCs_Mouse1.98913018
29TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.98550794
30NELFA_20434984_ChIP-Seq_ESCs_Mouse1.95476974
31SRY_22984422_ChIP-ChIP_TESTIS_Rat1.88868524
32E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.87023276
33VDR_21846776_ChIP-Seq_THP-1_Human1.86998318
34LXR_22292898_ChIP-Seq_THP-1_Human1.84277363
35PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.82790431
36FOXP3_21729870_ChIP-Seq_TREG_Human1.81637510
37* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.73524300
38POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.72337243
39GABP_19822575_ChIP-Seq_HepG2_Human1.70940106
40ELK3_25401928_ChIP-Seq_HUVEC_Human1.67055357
41FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.66698808
42* TTF2_22483619_ChIP-Seq_HELA_Human1.66639917
43ELF1_17652178_ChIP-ChIP_JURKAT_Human1.65848589
44PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.63168579
45SRF_21415370_ChIP-Seq_HL-1_Mouse1.62525755
46* NANOG_18555785_ChIP-Seq_MESCs_Mouse1.58828573
47MYC_22102868_ChIP-Seq_BL_Human1.58581041
48E2F4_17652178_ChIP-ChIP_JURKAT_Human1.55106495
49STAT3_1855785_ChIP-Seq_MESCs_Mouse1.54617932
50* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.53640013
51ELF1_20517297_ChIP-Seq_JURKAT_Human1.53386798
52CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.47835689
53YY1_22570637_ChIP-Seq_MALME-3M_Human1.45312586
54POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.42282956
55KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.41846589
56NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.41665563
57KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.41409053
58CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.41023076
59NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.40473932
60SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.40308525
61ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.39828409
62ELK1_22589737_ChIP-Seq_MCF10A_Human1.37333664
63TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.35315827
64RACK7_27058665_Chip-Seq_MCF-7_Human1.32543451
65CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.32049489
66ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.25097383
67MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.24918309
68THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.23598417
69* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.23223392
70* SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.22575724
71* CIITA_25753668_ChIP-Seq_RAJI_Human1.20736968
72BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.20178541
73SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.20018927
74NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.19381635
75HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.19195599
76* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.19090665
77OCT4_18692474_ChIP-Seq_MEFs_Mouse1.18365739
78SA1_27219007_Chip-Seq_ERYTHROID_Human1.18036152
79* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.17214694
80SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.16281442
81* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.16084918
82DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.14090746
83FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.12941317
84TET1_21451524_ChIP-Seq_MESCs_Mouse1.12726068
85TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.12069116
86DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.11188996
87BCOR_27268052_Chip-Seq_Bcells_Human1.10135533
88ZNF263_19887448_ChIP-Seq_K562_Human1.10033382
89ELK1_19687146_ChIP-ChIP_HELA_Human1.09859667
90SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.09344309
91* CTCF_26484167_Chip-Seq_Bcells_Mouse1.08693208
92* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.08358808
93KLF4_18555785_ChIP-Seq_MESCs_Mouse1.07418095
94CTCF_27219007_Chip-Seq_ERYTHROID_Human1.07312770
95* CTCF_18555785_ChIP-Seq_MESCs_Mouse1.07076478
96PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.06183763
97UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.05778815
98SOX2_18692474_ChIP-Seq_MEFs_Mouse1.04746864
99SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.03065037
100FOXP1_21924763_ChIP-Seq_HESCs_Human1.02576419
101TFEB_21752829_ChIP-Seq_HELA_Human1.02521456
102SOX2_18555785_ChIP-Seq_MESCs_Mouse1.01917414
103KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.01241641
104EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.00901298
105* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.00422466
106ATF3_27146783_Chip-Seq_COLON_Human0.99455694
107PHF8_20622854_ChIP-Seq_HELA_Human0.95957888
108P68_20966046_ChIP-Seq_HELA_Human0.94397769
109KDM5A_27292631_Chip-Seq_BREAST_Human0.92939744
110CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.92486697
111* RARG_19884340_ChIP-ChIP_MEFs_Mouse0.88858556
112* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.88857687
113CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.88802548
114MYC_18940864_ChIP-ChIP_HL60_Human0.88455823
115FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.88347248
116BCL6_27268052_Chip-Seq_Bcells_Human0.87784582
117AR_21909140_ChIP-Seq_LNCAP_Human0.86193629
118E2F1_20622854_ChIP-Seq_HELA_Human0.84743689
119E2F1_21310950_ChIP-Seq_MCF-7_Human0.84488612
120SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.82759008
121* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.82549308
122TBX5_21415370_ChIP-Seq_HL-1_Mouse0.82034297
123TCF3_18692474_ChIP-Seq_MEFs_Mouse0.81073295
124PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.80791150
125* POU5F1_18692474_ChIP-Seq_MESCs_Mouse0.80533424
126RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.79584539

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.01504718
2MP0004957_abnormal_blastocyst_morpholog3.58246400
3MP0005451_abnormal_body_composition3.44771585
4MP0003111_abnormal_nucleus_morphology3.36608601
5MP0003077_abnormal_cell_cycle3.20406448
6MP0003806_abnormal_nucleotide_metabolis3.14955357
7MP0010094_abnormal_chromosome_stability3.14397500
8MP0002877_abnormal_melanocyte_morpholog3.04260877
9MP0006035_abnormal_mitochondrial_morpho3.03225365
10MP0003718_maternal_effect2.98442904
11MP0008932_abnormal_embryonic_tissue2.96385846
12MP0005058_abnormal_lysosome_morphology2.70460478
13MP0002751_abnormal_autonomic_nervous2.49084158
14MP0003567_abnormal_fetal_cardiomyocyte2.39132083
15MP0005670_abnormal_white_adipose2.38589334
16MP0008007_abnormal_cellular_replicative2.33224916
17MP0001529_abnormal_vocalization2.30747490
18MP0004233_abnormal_muscle_weight2.20947753
19MP0000358_abnormal_cell_content/2.13259870
20MP0009278_abnormal_bone_marrow2.11131504
21MP0002160_abnormal_reproductive_system2.06441431
22MP0003646_muscle_fatigue2.00615414
23MP0003315_abnormal_perineum_morphology2.00504392
24MP0009840_abnormal_foam_cell1.93275484
25MP0005389_reproductive_system_phenotype1.84692763
26MP0003786_premature_aging1.83920147
27MP0006036_abnormal_mitochondrial_physio1.82565776
28MP0009333_abnormal_splenocyte_physiolog1.75496732
29MP0003123_paternal_imprinting1.74473570
30MP0008058_abnormal_DNA_repair1.73226288
31MP0001730_embryonic_growth_arrest1.70493066
32MP0001919_abnormal_reproductive_system1.69256610
33MP0000750_abnormal_muscle_regeneration1.65813180
34MP0000678_abnormal_parathyroid_gland1.59206781
35MP0006276_abnormal_autonomic_nervous1.56384987
36MP0004133_heterotaxia1.54948764
37MP0002009_preneoplasia1.54320953
38MP0000747_muscle_weakness1.53987509
39MP0000749_muscle_degeneration1.53976289
40MP0003283_abnormal_digestive_organ1.50975752
41MP0000350_abnormal_cell_proliferation1.49903270
42MP0000003_abnormal_adipose_tissue1.49873291
43MP0004084_abnormal_cardiac_muscle1.48142912
44MP0003186_abnormal_redox_activity1.46352124
45MP0000759_abnormal_skeletal_muscle1.38366196
46MP0002090_abnormal_vision1.36049235
47MP0008260_abnormal_autophagy1.35990505
48MP0001697_abnormal_embryo_size1.33431896
49MP0000372_irregular_coat_pigmentation1.30374050
50MP0008789_abnormal_olfactory_epithelium1.30161053
51MP0002735_abnormal_chemical_nociception1.29270483
52MP0005377_hearing/vestibular/ear_phenot1.25513677
53MP0003878_abnormal_ear_physiology1.25513677
54MP0004185_abnormal_adipocyte_glucose1.21265531
55MP0001542_abnormal_bone_strength1.21258084
56MP0003329_amyloid_beta_deposits1.20620952
57MP0004510_myositis1.19886808
58MP0005623_abnormal_meninges_morphology1.19348837
59MP0000537_abnormal_urethra_morphology1.18834477
60MP0000858_altered_metastatic_potential1.18647591
61MP0005257_abnormal_intraocular_pressure1.18554574
62MP0003705_abnormal_hypodermis_morpholog1.18431846
63MP0005171_absent_coat_pigmentation1.18007024
64MP0002653_abnormal_ependyma_morphology1.17064003
65MP0000681_abnormal_thyroid_gland1.16278258
66MP0005375_adipose_tissue_phenotype1.13119089
67MP0000751_myopathy1.11299295
68MP0005330_cardiomyopathy1.10917334
69MP0002080_prenatal_lethality1.10775268
70MP0002736_abnormal_nociception_after1.08127046
71MP0004859_abnormal_synaptic_plasticity1.07639728
72MP0005083_abnormal_biliary_tract1.07360962
73MP0002249_abnormal_larynx_morphology1.07206723
74MP0002269_muscular_atrophy1.06021673
75MP0000343_altered_response_to1.05822673
76MP0001346_abnormal_lacrimal_gland1.04024759
77MP0003191_abnormal_cellular_cholesterol1.03518728
78MP0001905_abnormal_dopamine_level1.02450095
79MP0001661_extended_life_span1.02303499
80MP0005380_embryogenesis_phenotype0.99699019
81MP0001672_abnormal_embryogenesis/_devel0.99699019
82MP0001849_ear_inflammation0.98925574
83MP0009672_abnormal_birth_weight0.97848478
84MP0002106_abnormal_muscle_physiology0.97130582
85MP0001853_heart_inflammation0.95051787
86MP0004087_abnormal_muscle_fiber0.94789308
87MP0010030_abnormal_orbit_morphology0.94740372
88MP0000313_abnormal_cell_death0.94304984
89MP0005666_abnormal_adipose_tissue0.94179437
90MP0003075_altered_response_to0.93144843
91MP0002163_abnormal_gland_morphology0.92793572
92MP0005266_abnormal_metabolism0.92550162
93MP0002837_dystrophic_cardiac_calcinosis0.92420599
94MP0002734_abnormal_mechanical_nocicepti0.91697354
95MP0005499_abnormal_olfactory_system0.91484861
96MP0005394_taste/olfaction_phenotype0.91484861
97MP0003984_embryonic_growth_retardation0.89975665
98MP0001727_abnormal_embryo_implantation0.89441896
99MP0001968_abnormal_touch/_nociception0.89258434
100MP0005165_increased_susceptibility_to0.89017963
101MP0002132_abnormal_respiratory_system0.88510961
102MP0002796_impaired_skin_barrier0.88480389
103MP0001970_abnormal_pain_threshold0.88046475
104MP0005384_cellular_phenotype0.88011754
105MP0009053_abnormal_anal_canal0.87874899
106MP0009046_muscle_twitch0.87508753
107MP0000733_abnormal_muscle_development0.86610874
108MP0002088_abnormal_embryonic_growth/wei0.85853882
109MP0001348_abnormal_lacrimal_gland0.85713987
110MP0003119_abnormal_digestive_system0.85018717
111MP0008770_decreased_survivor_rate0.82536587
112MP0004145_abnormal_muscle_electrophysio0.80278366
113MP0003879_abnormal_hair_cell0.79888622
114MP0002332_abnormal_exercise_endurance0.79267157
115MP0000049_abnormal_middle_ear0.79090805
116MP0008057_abnormal_DNA_replication0.76094013
117MP0002733_abnormal_thermal_nociception0.75316102
118MP0002970_abnormal_white_adipose0.75116615
119MP0003221_abnormal_cardiomyocyte_apopto0.75057300
120MP0003137_abnormal_impulse_conducting0.74259134
121MP0003938_abnormal_ear_development0.74153390
122MP0002019_abnormal_tumor_incidence0.73862495
123MP0002184_abnormal_innervation0.73299158
124MP0004147_increased_porphyrin_level0.71471705
125MP0002085_abnormal_embryonic_tissue0.69364512
126MP0004811_abnormal_neuron_physiology0.69087607
127MP0001243_abnormal_dermal_layer0.67628422
128MP0004858_abnormal_nervous_system0.67371564
129MP0003656_abnormal_erythrocyte_physiolo0.67110287
130MP0005621_abnormal_cell_physiology0.66856933
131MP0004036_abnormal_muscle_relaxation0.66563404
132MP0005369_muscle_phenotype0.66415890
133MP0002089_abnormal_postnatal_growth/wei0.65698004
134MP0004142_abnormal_muscle_tone0.65408572
135MP0002060_abnormal_skin_morphology0.62089673
136MP0001145_abnormal_male_reproductive0.61887379
137MP0005395_other_phenotype0.61769289
138MP0000428_abnormal_craniofacial_morphol0.61029350
139MP0005508_abnormal_skeleton_morphology0.60609637
140MP0004197_abnormal_fetal_growth/weight/0.58813505
141MP0000490_abnormal_crypts_of0.58754719
142MP0000467_abnormal_esophagus_morphology0.58264480
143MP0005397_hematopoietic_system_phenotyp0.58128456
144MP0001545_abnormal_hematopoietic_system0.58128456
145MP0005501_abnormal_skin_physiology0.57645669
146MP0002169_no_abnormal_phenotype0.56507314
147MP0003880_abnormal_central_pattern0.56120631

Predicted human phenotypes

RankGene SetZ-score
1Elevated erythrocyte sedimentation rate (HP:0003565)6.09005383
2Conjugated hyperbilirubinemia (HP:0002908)5.99969684
3Peritonitis (HP:0002586)5.55900428
4Progressive external ophthalmoplegia (HP:0000590)5.26146038
5Neuroendocrine neoplasm (HP:0100634)4.10812974
6Progressive cerebellar ataxia (HP:0002073)4.02671822
7Cholecystitis (HP:0001082)3.96005465
8Abnormal gallbladder physiology (HP:0012438)3.96005465
9Acute necrotizing encephalopathy (HP:0006965)3.82597413
10Increased hepatocellular lipid droplets (HP:0006565)3.82227656
11Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.79505638
12Hepatocellular necrosis (HP:0001404)3.73529821
13Insidious onset (HP:0003587)3.72820698
14Termporal pattern (HP:0011008)3.72820698
15Breast hypoplasia (HP:0003187)3.72649373
16Ragged-red muscle fibers (HP:0003200)3.70771881
17Mitochondrial inheritance (HP:0001427)3.63470938
18Cerebral hypomyelination (HP:0006808)3.47089835
19Abnormal mitochondria in muscle tissue (HP:0008316)3.47058120
20Lipid accumulation in hepatocytes (HP:0006561)3.34371109
21Renal tubular acidosis (HP:0001947)3.26724308
22Pancreatic cysts (HP:0001737)3.26439554
23Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.25696509
24Hepatic necrosis (HP:0002605)3.22053531
25Reticulocytopenia (HP:0001896)3.20942637
26Nephrogenic diabetes insipidus (HP:0009806)3.19954611
27Increased CSF lactate (HP:0002490)3.17065482
28Myopathic facies (HP:0002058)3.12906574
29Pheochromocytoma (HP:0002666)3.11802974
30Carpal bone hypoplasia (HP:0001498)3.05233003
31Broad distal phalanx of finger (HP:0009836)3.03857146
32Central scotoma (HP:0000603)3.03335320
33Achilles tendon contracture (HP:0001771)3.02810068
34Acute encephalopathy (HP:0006846)3.02514732
35Increased serum lactate (HP:0002151)3.02464714
36Shoulder girdle muscle weakness (HP:0003547)3.01245903
37Renal Fanconi syndrome (HP:0001994)2.98207473
38Congenital, generalized hypertrichosis (HP:0004540)2.93762735
39Dyschromatopsia (HP:0007641)2.85843204
40Exertional dyspnea (HP:0002875)2.82809800
41Increased intramyocellular lipid droplets (HP:0012240)2.80755033
423-Methylglutaconic aciduria (HP:0003535)2.80444933
43Progressive macrocephaly (HP:0004481)2.79636507
44External ophthalmoplegia (HP:0000544)2.77874687
45Renal tubular dysfunction (HP:0000124)2.76935301
46Distal lower limb muscle weakness (HP:0009053)2.75732368
47Microvesicular hepatic steatosis (HP:0001414)2.75537386
48Rimmed vacuoles (HP:0003805)2.73860514
49Exercise intolerance (HP:0003546)2.73425474
50Increased connective tissue (HP:0009025)2.73361824
51Chromosomal breakage induced by crosslinking agents (HP:0003221)2.62961875
52Pelvic girdle muscle weakness (HP:0003749)2.60896287
53Abnormality of the peritoneum (HP:0002585)2.57785626
54Distal upper limb amyotrophy (HP:0007149)2.56478622
55Upper limb amyotrophy (HP:0009129)2.56478622
56Aplasia/Hypoplasia of the sacrum (HP:0008517)2.55734750
57Vertebral compression fractures (HP:0002953)2.54597916
58Type I transferrin isoform profile (HP:0003642)2.51829810
59Hyperacusis (HP:0010780)2.50434194
60Abnormality of cells of the erythroid lineage (HP:0012130)2.48643681
61Abnormality of the Achilles tendon (HP:0005109)2.47827267
62Insomnia (HP:0100785)2.45801194
63Hypertensive crisis (HP:0100735)2.44009334
64Birth length less than 3rd percentile (HP:0003561)2.42828778
65Hypokinesia (HP:0002375)2.41896153
66Decreased activity of mitochondrial respiratory chain (HP:0008972)2.41285366
67Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.41285366
68Aplastic anemia (HP:0001915)2.40312317
69Optic disc pallor (HP:0000543)2.39604985
70Increased serum pyruvate (HP:0003542)2.38876670
71Abnormality of glycolysis (HP:0004366)2.38876670
72Abnormality of the umbilical cord (HP:0010881)2.36586096
73Prolonged neonatal jaundice (HP:0006579)2.35900746
74Abnormal number of erythroid precursors (HP:0012131)2.34262292
75Abnormality of the musculature of the pelvis (HP:0001469)2.32628418
76Abnormality of the hip-girdle musculature (HP:0001445)2.32628418
77Increased muscle lipid content (HP:0009058)2.32413069
78Rough bone trabeculation (HP:0100670)2.31454048
79Lactic acidosis (HP:0003128)2.30057184
80Emotional lability (HP:0000712)2.29624581
81Neoplasm of the peripheral nervous system (HP:0100007)2.29390528
82Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.28356276
83Opisthotonus (HP:0002179)2.24396590
84Fasciculations (HP:0002380)2.23760924
85Centrally nucleated skeletal muscle fibers (HP:0003687)2.23723158
86Hand muscle atrophy (HP:0009130)2.23717751
87Patellar aplasia (HP:0006443)2.22778807
88CNS demyelination (HP:0007305)2.20350532
89Chromsome breakage (HP:0040012)2.19072052
90Aplasia/Hypoplasia of the patella (HP:0006498)2.18427797
91Respiratory difficulties (HP:0002880)2.18124787
92Macrocytic anemia (HP:0001972)2.16997055
93Generalized amyotrophy (HP:0003700)2.16473727
94Distal lower limb amyotrophy (HP:0008944)2.16365934
95Limb dystonia (HP:0002451)2.15023902
96Abnormality of skeletal muscle fiber size (HP:0012084)2.14719136
97Abnormal trabecular bone morphology (HP:0100671)2.14675805
98Stridor (HP:0010307)2.14501640
99Increased variability in muscle fiber diameter (HP:0003557)2.14297483
100Progressive sensorineural hearing impairment (HP:0000408)2.14264670
101Cholelithiasis (HP:0001081)2.13984648
102Multiple enchondromatosis (HP:0005701)2.12244150
103Progressive muscle weakness (HP:0003323)2.09277536
104Selective tooth agenesis (HP:0001592)2.07754524
105Difficulty climbing stairs (HP:0003551)2.07494481
106Pancreatic fibrosis (HP:0100732)2.06764851
107Degeneration of anterior horn cells (HP:0002398)2.06489993
108Abnormality of the anterior horn cell (HP:0006802)2.06489993
109Reduced subcutaneous adipose tissue (HP:0003758)2.06075043
110Areflexia of lower limbs (HP:0002522)2.04226405
111Horizontal nystagmus (HP:0000666)2.04176465
112Trismus (HP:0000211)2.03652724
113Ureteral duplication (HP:0000073)2.03652663
114Lissencephaly (HP:0001339)2.03412327
115Abnormality of pain sensation (HP:0010832)2.02634971
116Impaired pain sensation (HP:0007328)2.02634971
117Cerebral edema (HP:0002181)2.02482309
118Axonal loss (HP:0003447)2.01521782
119Rhabdomyolysis (HP:0003201)2.01257455
120Premature rupture of membranes (HP:0001788)2.01079929
121Respiratory failure (HP:0002878)2.00959527
122Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.99475100
123Abnormal protein N-linked glycosylation (HP:0012347)1.99475100
124Abnormal protein glycosylation (HP:0012346)1.99475100
125Abnormal glycosylation (HP:0012345)1.99475100
126Delusions (HP:0000746)1.98688681
127Hypoplasia of the capital femoral epiphysis (HP:0003090)1.98577660
128Pallor (HP:0000980)1.97598999
129Entropion (HP:0000621)1.96595464
130Long palpebral fissure (HP:0000637)1.96247162
131Testicular atrophy (HP:0000029)1.94218944
132Horseshoe kidney (HP:0000085)1.93750735
133True hermaphroditism (HP:0010459)1.93211110
134Absent radius (HP:0003974)1.92390866
135Tinnitus (HP:0000360)1.91651322
136Microretrognathia (HP:0000308)1.91539274
137Scotoma (HP:0000575)1.89936892
138Myokymia (HP:0002411)1.89681434
139Abnormality of the gallbladder (HP:0005264)1.88325170
140Upper limb muscle weakness (HP:0003484)1.87324802
141Annular pancreas (HP:0001734)1.86547202
142Abnormality of the distal phalanges of the toes (HP:0010182)1.85887180
143Abnormal gallbladder morphology (HP:0012437)1.82825760
144Abnormal umbilical cord blood vessels (HP:0011403)1.82556117
145Single umbilical artery (HP:0001195)1.82556117
146Abnormality of the fetal cardiovascular system (HP:0010948)1.82556117
147Secondary amenorrhea (HP:0000869)1.81770461
148Reduced antithrombin III activity (HP:0001976)1.80826812
149Progressive microcephaly (HP:0000253)1.80754662
150Spastic paraparesis (HP:0002313)1.79457004
151Abnormalities of placenta or umbilical cord (HP:0001194)1.78311644
152Abnormality of glycolipid metabolism (HP:0010969)1.78032750
153Abnormality of liposaccharide metabolism (HP:0010968)1.78032750
154Abnormality of glycosphingolipid metabolism (HP:0004343)1.78032750
155Death in infancy (HP:0001522)1.73147451
156Overriding aorta (HP:0002623)1.71847171
157Truncus arteriosus (HP:0001660)1.71788242
158Athetosis (HP:0002305)1.71662526
159Ulnar bowing (HP:0003031)1.70447955
160Retinal dysplasia (HP:0007973)1.69954531

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.93155995
2NME24.78312463
3MAP3K114.37169933
4VRK24.26758133
5TESK23.10533331
6WEE12.97151682
7SMG12.83507450
8TLK12.71776620
9TESK12.49182802
10SRPK12.33939026
11NME12.31523542
12NUAK12.31136943
13PIM22.30721432
14EIF2AK12.29751636
15LIMK12.28396097
16ARAF2.22535505
17DYRK32.19563749
18STK161.97962839
19TSSK61.95556209
20RPS6KA41.84755619
21NEK11.83387398
22TRIB31.79306074
23PLK41.74926663
24TAOK21.72905213
25BRSK11.72096602
26ERN11.62450753
27BRAF1.59372784
28ICK1.57626553
29AURKA1.50459803
30KDR1.49148961
31PLK31.47677618
32EPHA21.40869424
33PRKD31.35729800
34VRK11.32900036
35MAP2K21.32002144
36PLK11.25796605
37EPHB21.23902062
38NEK91.23846248
39EIF2AK31.22450994
40PBK1.20709965
41NEK21.15477283
42CSNK1G31.07622983
43MAP3K81.07143916
44EEF2K1.03026400
45TTN0.99820682
46DYRK20.97461777
47PLK20.95153951
48SIK10.93253212
49LATS20.92045689
50ZAK0.91507541
51PDK20.90648236
52CHEK20.89975267
53TTK0.88942484
54AURKB0.87486488
55BRSK20.85538718
56LRRK20.84857390
57LMTK20.84155903
58MARK10.83638730
59PRPF4B0.83598130
60GRK50.81794957
61SIK30.81483122
62AKT30.79748922
63PAK10.79383444
64CDK80.78211241
65CSNK1A1L0.77362076
66PAK60.75076645
67CSNK2A20.74273683
68PRKCI0.73575341
69CDC70.72156742
70ABL20.72051303
71CCNB10.71864807
72MINK10.67718085
73AKT20.66777864
74DAPK30.66552213
75MAPK110.66116765
76CDK140.65791472
77TBK10.64959305
78CSNK2A10.60781883
79CDK70.60648359
80BCKDK0.60505113
81CSNK1G20.59927256
82CDK40.59893550
83CAMK2G0.56436931
84MYLK0.56123245
85RPS6KA50.54368056
86IRAK30.54163754
87MOS0.53215411
88PTK20.53020574
89PINK10.51135207
90MKNK10.50689930
91CAMK2B0.49932192
92PDK30.49664884
93PDK40.49664884
94MAP2K30.48833886
95BLK0.48466902
96STK100.48192723
97OBSCN0.46649599
98CHEK10.46225869
99PNCK0.46137660
100SCYL20.45216246
101MAP2K70.44914612
102DAPK10.44254722
103PAK40.43892346
104CSNK1G10.43326401
105BMX0.42933632
106MKNK20.42767231
107ILK0.42312478
108MAP3K120.42248530
109STK40.40284458
110CDK180.40226735
111PRKCG0.40136033
112RPS6KA60.39560401
113MAP3K30.39079961
114RPS6KB20.38708398
115RPS6KC10.38203834
116RPS6KL10.38203834
117MAP2K10.37949051
118CDK150.37004571
119CAMK2D0.36025043
120TAOK10.35632622
121IRAK20.35364186
122CDK11A0.34853385
123ATR0.34524635
124MAPKAPK30.34431794
125SIK20.33910357
126PRKG20.33858417
127CDK190.32907801
128MTOR0.31389614
129CSNK1E0.31254975
130PRKD20.30817847
131NTRK10.30013078
132CDK20.28979177
133PRKCD0.28556873
134PHKG20.28334911
135PHKG10.28334911
136MST1R0.28315539
137UHMK10.28240201
138CSNK1A10.27208726
139GRK60.26026564
140CASK0.24268653
141CAMKK10.23645542
142BCR0.23313179

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030505.34137479
2Ribosome_Homo sapiens_hsa030105.01743139
3RNA polymerase_Homo sapiens_hsa030203.74003690
4Oxidative phosphorylation_Homo sapiens_hsa001903.55561805
5DNA replication_Homo sapiens_hsa030303.55427481
6Terpenoid backbone biosynthesis_Homo sapiens_hsa009003.42364701
7Parkinsons disease_Homo sapiens_hsa050123.22253396
8Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.91327094
9Mismatch repair_Homo sapiens_hsa034302.83947929
10Spliceosome_Homo sapiens_hsa030402.72708312
11Pyrimidine metabolism_Homo sapiens_hsa002402.56681465
12Huntingtons disease_Homo sapiens_hsa050162.49493777
13RNA transport_Homo sapiens_hsa030132.31504701
14Sulfur relay system_Homo sapiens_hsa041222.12452707
15Nucleotide excision repair_Homo sapiens_hsa034202.11524183
16Alzheimers disease_Homo sapiens_hsa050102.10141602
17Base excision repair_Homo sapiens_hsa034101.98838367
18Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.77934659
19Fatty acid elongation_Homo sapiens_hsa000621.70632362
20Vitamin B6 metabolism_Homo sapiens_hsa007501.66955401
21Cardiac muscle contraction_Homo sapiens_hsa042601.63007726
22Homologous recombination_Homo sapiens_hsa034401.51972865
23Cell cycle_Homo sapiens_hsa041101.51025682
24Folate biosynthesis_Homo sapiens_hsa007901.50472039
25Purine metabolism_Homo sapiens_hsa002301.39893736
26Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.33625760
27Pentose phosphate pathway_Homo sapiens_hsa000301.17165541
28Basal transcription factors_Homo sapiens_hsa030221.14651327
29Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.14438141
30p53 signaling pathway_Homo sapiens_hsa041151.11839902
312-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.11598229
32Biosynthesis of amino acids_Homo sapiens_hsa012301.09169331
33Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.08543511
34Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.01729576
35Epstein-Barr virus infection_Homo sapiens_hsa051690.99586494
36Cysteine and methionine metabolism_Homo sapiens_hsa002700.98327338
37Collecting duct acid secretion_Homo sapiens_hsa049660.96652647
38Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.96240214
39Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.95097118
40Fructose and mannose metabolism_Homo sapiens_hsa000510.94994472
41Carbon metabolism_Homo sapiens_hsa012000.94168414
42Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.89706614
43N-Glycan biosynthesis_Homo sapiens_hsa005100.87588456
44Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.85558962
45Other glycan degradation_Homo sapiens_hsa005110.83929859
46Fanconi anemia pathway_Homo sapiens_hsa034600.80735567
47Oocyte meiosis_Homo sapiens_hsa041140.80130042
48One carbon pool by folate_Homo sapiens_hsa006700.79847431
49Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.79746288
50Drug metabolism - other enzymes_Homo sapiens_hsa009830.78956210
51Central carbon metabolism in cancer_Homo sapiens_hsa052300.78377368
52Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.77570981
53Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.77333921
54Synaptic vesicle cycle_Homo sapiens_hsa047210.73701120
55Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.73468444
56RNA degradation_Homo sapiens_hsa030180.73267495
57Regulation of autophagy_Homo sapiens_hsa041400.70922065
58Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.68662374
59Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.67882111
60Non-homologous end-joining_Homo sapiens_hsa034500.65137327
61Protein export_Homo sapiens_hsa030600.64972365
62Glutathione metabolism_Homo sapiens_hsa004800.63361982
63Legionellosis_Homo sapiens_hsa051340.58441149
64Metabolic pathways_Homo sapiens_hsa011000.58093309
65Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.56991907
66Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.56677751
67Lysosome_Homo sapiens_hsa041420.54764116
68Glycosaminoglycan degradation_Homo sapiens_hsa005310.54277503
69Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.51574392
70Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.51559660
71Antigen processing and presentation_Homo sapiens_hsa046120.50893634
72Vibrio cholerae infection_Homo sapiens_hsa051100.47735620
73Cyanoamino acid metabolism_Homo sapiens_hsa004600.47084337
74Pyruvate metabolism_Homo sapiens_hsa006200.46616340
75Tyrosine metabolism_Homo sapiens_hsa003500.44435305
76Phagosome_Homo sapiens_hsa041450.43989440
77Thyroid cancer_Homo sapiens_hsa052160.42963744
78Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.42734780
79Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.36649838
80Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.36192414
81Arachidonic acid metabolism_Homo sapiens_hsa005900.35868076
82Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.35819955
83HIF-1 signaling pathway_Homo sapiens_hsa040660.35319034
84Systemic lupus erythematosus_Homo sapiens_hsa053220.32365971
85Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.31988952
86Arginine and proline metabolism_Homo sapiens_hsa003300.31612781
87Graft-versus-host disease_Homo sapiens_hsa053320.30648615
88mRNA surveillance pathway_Homo sapiens_hsa030150.30417229
89Rheumatoid arthritis_Homo sapiens_hsa053230.29629217
90Peroxisome_Homo sapiens_hsa041460.27303975
91Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.26839878
92Galactose metabolism_Homo sapiens_hsa000520.26786819
93Fatty acid metabolism_Homo sapiens_hsa012120.24520088
94SNARE interactions in vesicular transport_Homo sapiens_hsa041300.23755427
95Apoptosis_Homo sapiens_hsa042100.23406957
96Steroid biosynthesis_Homo sapiens_hsa001000.21083220
97Linoleic acid metabolism_Homo sapiens_hsa005910.20622712
98Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.20293122
99VEGF signaling pathway_Homo sapiens_hsa043700.19691188
100Phenylalanine metabolism_Homo sapiens_hsa003600.17382289
101Viral carcinogenesis_Homo sapiens_hsa052030.16580511
102Arginine biosynthesis_Homo sapiens_hsa002200.16578403
103Bladder cancer_Homo sapiens_hsa052190.16528086
104AMPK signaling pathway_Homo sapiens_hsa041520.16378568
105Allograft rejection_Homo sapiens_hsa053300.13845750
106Sulfur metabolism_Homo sapiens_hsa009200.13358182
107Salmonella infection_Homo sapiens_hsa051320.12916890
108Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.10964334
109Prion diseases_Homo sapiens_hsa050200.10847096
110Asthma_Homo sapiens_hsa053100.10577964
111Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.09117405
112Endocytosis_Homo sapiens_hsa041440.09075067
113Lysine degradation_Homo sapiens_hsa003100.08763535
114Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.08285667
115Glycerophospholipid metabolism_Homo sapiens_hsa005640.07971351
116Alcoholism_Homo sapiens_hsa050340.07217365
117HTLV-I infection_Homo sapiens_hsa051660.06642328
118alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.06560954
119Shigellosis_Homo sapiens_hsa051310.03561247
120Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.01866352
121Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.01616260
122Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980-0.0189112
123Type I diabetes mellitus_Homo sapiens_hsa04940-0.0042648

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