Rank | Gene Set | Z-score |
---|---|---|
1 | regulation of mitochondrial translation (GO:0070129) | 6.26573034 |
2 | arginine catabolic process (GO:0006527) | 6.08068864 |
3 | protein maturation by protein folding (GO:0022417) | 5.59922196 |
4 | proteasome assembly (GO:0043248) | 5.17467274 |
5 | DNA deamination (GO:0045006) | 5.11369657 |
6 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.03716999 |
7 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 4.89195907 |
8 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.88888308 |
9 | mitochondrial fusion (GO:0008053) | 4.81414908 |
10 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 4.75234860 |
11 | mitotic nuclear envelope reassembly (GO:0007084) | 4.61785953 |
12 | nuclear envelope reassembly (GO:0031468) | 4.61785953 |
13 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 4.57955334 |
14 | 7-methylguanosine mRNA capping (GO:0006370) | 4.53179573 |
15 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.48494890 |
16 | ATP synthesis coupled proton transport (GO:0015986) | 4.48494890 |
17 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 4.44773222 |
18 | formation of translation preinitiation complex (GO:0001731) | 4.44334570 |
19 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 4.44174281 |
20 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 4.39943326 |
21 | negative regulation of ligase activity (GO:0051352) | 4.39943326 |
22 | viral transcription (GO:0019083) | 4.39704970 |
23 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.33963693 |
24 | translational termination (GO:0006415) | 4.33005830 |
25 | 7-methylguanosine RNA capping (GO:0009452) | 4.32974160 |
26 | RNA capping (GO:0036260) | 4.32974160 |
27 | GDP-mannose metabolic process (GO:0019673) | 4.26254112 |
28 | peptidyl-arginine omega-N-methylation (GO:0035247) | 4.26046271 |
29 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 4.20906878 |
30 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 4.16420711 |
31 | establishment of integrated proviral latency (GO:0075713) | 4.16179249 |
32 | DNA replication checkpoint (GO:0000076) | 4.11714860 |
33 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 4.07602756 |
34 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 4.07602756 |
35 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 4.07602756 |
36 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 4.06230382 |
37 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 4.06230382 |
38 | inner mitochondrial membrane organization (GO:0007007) | 4.06003986 |
39 | establishment of viral latency (GO:0019043) | 4.00096084 |
40 | positive regulation of ligase activity (GO:0051351) | 3.99889702 |
41 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.98527995 |
42 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.98527995 |
43 | translational initiation (GO:0006413) | 3.97780425 |
44 | purine nucleobase biosynthetic process (GO:0009113) | 3.96103356 |
45 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.95800132 |
46 | histone arginine methylation (GO:0034969) | 3.94489536 |
47 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.94419252 |
48 | spliceosomal snRNP assembly (GO:0000387) | 3.94278046 |
49 | protein neddylation (GO:0045116) | 3.94270009 |
50 | translational elongation (GO:0006414) | 3.93611725 |
51 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.87259500 |
52 | sequestering of actin monomers (GO:0042989) | 3.87107711 |
53 | proline biosynthetic process (GO:0006561) | 3.87025702 |
54 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.86984453 |
55 | ribosomal small subunit biogenesis (GO:0042274) | 3.86120251 |
56 | termination of RNA polymerase III transcription (GO:0006386) | 3.82384982 |
57 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.82384982 |
58 | COPI coating of Golgi vesicle (GO:0048205) | 3.78656389 |
59 | Golgi transport vesicle coating (GO:0048200) | 3.78656389 |
60 | nucleobase biosynthetic process (GO:0046112) | 3.78634376 |
61 | maturation of SSU-rRNA (GO:0030490) | 3.78334354 |
62 | translation (GO:0006412) | 3.77268583 |
63 | establishment of protein localization to mitochondrion (GO:0072655) | 3.76902249 |
64 | ribosomal large subunit biogenesis (GO:0042273) | 3.75055355 |
65 | protein targeting to mitochondrion (GO:0006626) | 3.75027215 |
66 | cullin deneddylation (GO:0010388) | 3.71493238 |
67 | cellular protein complex disassembly (GO:0043624) | 3.64379686 |
68 | protein deneddylation (GO:0000338) | 3.63628845 |
69 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.62864939 |
70 | negative regulation of release of cytochrome c from mitochondria (GO:0090201) | 3.62796260 |
71 | positive regulation of cell cycle arrest (GO:0071158) | 3.62445348 |
72 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 3.61921075 |
73 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 3.61311231 |
74 | DNA strand elongation (GO:0022616) | 3.60500618 |
75 | regulation of oxidative phosphorylation (GO:0002082) | 3.60294208 |
76 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.58648905 |
77 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.58513078 |
78 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.57738870 |
79 | ribosome biogenesis (GO:0042254) | 3.57233031 |
80 | regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:1902235 | 3.53514141 |
81 | protein complex biogenesis (GO:0070271) | 3.52580853 |
82 | UTP biosynthetic process (GO:0006228) | 3.52545018 |
83 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.52036075 |
84 | cotranslational protein targeting to membrane (GO:0006613) | 3.50934844 |
85 | protein targeting to ER (GO:0045047) | 3.50515711 |
86 | cytochrome complex assembly (GO:0017004) | 3.49263202 |
87 | chaperone-mediated protein transport (GO:0072321) | 3.49197417 |
88 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.48984757 |
89 | protein localization to mitochondrion (GO:0070585) | 3.47809346 |
90 | regulation of ligase activity (GO:0051340) | 3.46858653 |
91 | viral life cycle (GO:0019058) | 3.46272229 |
92 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 3.44090564 |
93 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.43697565 |
94 | nitric oxide biosynthetic process (GO:0006809) | 3.42817661 |
95 | ribosomal small subunit assembly (GO:0000028) | 3.42616063 |
96 | respiratory electron transport chain (GO:0022904) | 3.41194762 |
97 | ribosome assembly (GO:0042255) | 3.40097556 |
98 | rRNA modification (GO:0000154) | 3.39335280 |
99 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.38366748 |
100 | cellular component biogenesis (GO:0044085) | 3.37690682 |
101 | peptidyl-arginine methylation (GO:0018216) | 3.37321647 |
102 | peptidyl-arginine N-methylation (GO:0035246) | 3.37321647 |
103 | nucleobase-containing small molecule interconversion (GO:0015949) | 3.35959614 |
104 | GTP biosynthetic process (GO:0006183) | 3.35398366 |
105 | oxidative phosphorylation (GO:0006119) | 3.35322332 |
106 | regulation of translational termination (GO:0006449) | 3.34026704 |
107 | protein localization to endoplasmic reticulum (GO:0070972) | 3.34026081 |
108 | iron-sulfur cluster assembly (GO:0016226) | 3.33894618 |
109 | metallo-sulfur cluster assembly (GO:0031163) | 3.33894618 |
110 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 3.33176868 |
111 | electron transport chain (GO:0022900) | 3.32427397 |
112 | regulation of ruffle assembly (GO:1900027) | 3.32059537 |
113 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.30863812 |
114 | citrulline metabolic process (GO:0000052) | 3.29839614 |
115 | DNA damage response, detection of DNA damage (GO:0042769) | 3.29826810 |
116 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.29612523 |
117 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.28460675 |
118 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 3.27302625 |
119 | arginine metabolic process (GO:0006525) | 3.24817712 |
120 | protein retention in ER lumen (GO:0006621) | 3.23798613 |
121 | pseudouridine synthesis (GO:0001522) | 3.21955600 |
122 | CTP biosynthetic process (GO:0006241) | 3.19934046 |
123 | CTP metabolic process (GO:0046036) | 3.19934046 |
124 | base-excision repair, AP site formation (GO:0006285) | 3.18548576 |
125 | transcription from mitochondrial promoter (GO:0006390) | 3.18208407 |
126 | rRNA processing (GO:0006364) | 3.18033156 |
127 | 2-deoxyribonucleotide biosynthetic process (GO:0009265) | 3.17654138 |
128 | deoxyribose phosphate biosynthetic process (GO:0046385) | 3.17654138 |
129 | transcription from RNA polymerase I promoter (GO:0006360) | 3.16190762 |
130 | protein complex disassembly (GO:0043241) | 3.15516127 |
131 | G1/S transition of mitotic cell cycle (GO:0000082) | 3.15003031 |
132 | UTP metabolic process (GO:0046051) | 3.12846580 |
133 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 3.10031382 |
134 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 3.09263605 |
135 | pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208) | 3.04944764 |
136 | regulation of translational fidelity (GO:0006450) | 3.04784797 |
137 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 3.01864087 |
138 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 3.00510676 |
139 | lipopolysaccharide biosynthetic process (GO:0009103) | 2.98086622 |
140 | DNA unwinding involved in DNA replication (GO:0006268) | 2.96179520 |
141 | protein insertion into membrane (GO:0051205) | 2.92916489 |
142 | pentose-phosphate shunt (GO:0006098) | 2.91371716 |
143 | transcription-coupled nucleotide-excision repair (GO:0006283) | 2.91334559 |
144 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 2.87822695 |
145 | UV protection (GO:0009650) | 2.86418515 |
146 | base-excision repair (GO:0006284) | 2.85093336 |
147 | pentose metabolic process (GO:0019321) | 2.83274963 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 6.81236107 |
2 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 4.23801634 |
3 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.99997583 |
4 | E2F7_22180533_ChIP-Seq_HELA_Human | 3.73174740 |
5 | * JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.73144074 |
6 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.59680399 |
7 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.49658926 |
8 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.45092414 |
9 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.30788091 |
10 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.12256440 |
11 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 3.01638253 |
12 | * MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.84759253 |
13 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.80380316 |
14 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.80128745 |
15 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.73244912 |
16 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.44619230 |
17 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.40325701 |
18 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.24859189 |
19 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.10903642 |
20 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.06855890 |
21 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.06704530 |
22 | * YY1_21170310_ChIP-Seq_MESCs_Mouse | 2.06581476 |
23 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.06548085 |
24 | * VDR_23849224_ChIP-Seq_CD4+_Human | 2.05109023 |
25 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.02518709 |
26 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.01281665 |
27 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 2.01278944 |
28 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.98913018 |
29 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.98550794 |
30 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.95476974 |
31 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.88868524 |
32 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.87023276 |
33 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.86998318 |
34 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.84277363 |
35 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.82790431 |
36 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.81637510 |
37 | * ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.73524300 |
38 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.72337243 |
39 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.70940106 |
40 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.67055357 |
41 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.66698808 |
42 | * TTF2_22483619_ChIP-Seq_HELA_Human | 1.66639917 |
43 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.65848589 |
44 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.63168579 |
45 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.62525755 |
46 | * NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.58828573 |
47 | MYC_22102868_ChIP-Seq_BL_Human | 1.58581041 |
48 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.55106495 |
49 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.54617932 |
50 | * CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.53640013 |
51 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.53386798 |
52 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.47835689 |
53 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.45312586 |
54 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.42282956 |
55 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.41846589 |
56 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.41665563 |
57 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.41409053 |
58 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.41023076 |
59 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.40473932 |
60 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.40308525 |
61 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.39828409 |
62 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.37333664 |
63 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.35315827 |
64 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.32543451 |
65 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.32049489 |
66 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.25097383 |
67 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.24918309 |
68 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.23598417 |
69 | * CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.23223392 |
70 | * SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.22575724 |
71 | * CIITA_25753668_ChIP-Seq_RAJI_Human | 1.20736968 |
72 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.20178541 |
73 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.20018927 |
74 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.19381635 |
75 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.19195599 |
76 | * MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.19090665 |
77 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 1.18365739 |
78 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.18036152 |
79 | * ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.17214694 |
80 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 1.16281442 |
81 | * SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.16084918 |
82 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.14090746 |
83 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.12941317 |
84 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.12726068 |
85 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.12069116 |
86 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.11188996 |
87 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.10135533 |
88 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.10033382 |
89 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.09859667 |
90 | SETDB1_19884255_ChIP-Seq_MESCs_Mouse | 1.09344309 |
91 | * CTCF_26484167_Chip-Seq_Bcells_Mouse | 1.08693208 |
92 | * YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.08358808 |
93 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.07418095 |
94 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.07312770 |
95 | * CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.07076478 |
96 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.06183763 |
97 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.05778815 |
98 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 1.04746864 |
99 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 1.03065037 |
100 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 1.02576419 |
101 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.02521456 |
102 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.01917414 |
103 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.01241641 |
104 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.00901298 |
105 | * FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.00422466 |
106 | ATF3_27146783_Chip-Seq_COLON_Human | 0.99455694 |
107 | PHF8_20622854_ChIP-Seq_HELA_Human | 0.95957888 |
108 | P68_20966046_ChIP-Seq_HELA_Human | 0.94397769 |
109 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.92939744 |
110 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.92486697 |
111 | * RARG_19884340_ChIP-ChIP_MEFs_Mouse | 0.88858556 |
112 | * CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.88857687 |
113 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.88802548 |
114 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.88455823 |
115 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.88347248 |
116 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.87784582 |
117 | AR_21909140_ChIP-Seq_LNCAP_Human | 0.86193629 |
118 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.84743689 |
119 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 0.84488612 |
120 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.82759008 |
121 | * ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.82549308 |
122 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.82034297 |
123 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 0.81073295 |
124 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.80791150 |
125 | * POU5F1_18692474_ChIP-Seq_MESCs_Mouse | 0.80533424 |
126 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.79584539 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 5.01504718 |
2 | MP0004957_abnormal_blastocyst_morpholog | 3.58246400 |
3 | MP0005451_abnormal_body_composition | 3.44771585 |
4 | MP0003111_abnormal_nucleus_morphology | 3.36608601 |
5 | MP0003077_abnormal_cell_cycle | 3.20406448 |
6 | MP0003806_abnormal_nucleotide_metabolis | 3.14955357 |
7 | MP0010094_abnormal_chromosome_stability | 3.14397500 |
8 | MP0002877_abnormal_melanocyte_morpholog | 3.04260877 |
9 | MP0006035_abnormal_mitochondrial_morpho | 3.03225365 |
10 | MP0003718_maternal_effect | 2.98442904 |
11 | MP0008932_abnormal_embryonic_tissue | 2.96385846 |
12 | MP0005058_abnormal_lysosome_morphology | 2.70460478 |
13 | MP0002751_abnormal_autonomic_nervous | 2.49084158 |
14 | MP0003567_abnormal_fetal_cardiomyocyte | 2.39132083 |
15 | MP0005670_abnormal_white_adipose | 2.38589334 |
16 | MP0008007_abnormal_cellular_replicative | 2.33224916 |
17 | MP0001529_abnormal_vocalization | 2.30747490 |
18 | MP0004233_abnormal_muscle_weight | 2.20947753 |
19 | MP0000358_abnormal_cell_content/ | 2.13259870 |
20 | MP0009278_abnormal_bone_marrow | 2.11131504 |
21 | MP0002160_abnormal_reproductive_system | 2.06441431 |
22 | MP0003646_muscle_fatigue | 2.00615414 |
23 | MP0003315_abnormal_perineum_morphology | 2.00504392 |
24 | MP0009840_abnormal_foam_cell | 1.93275484 |
25 | MP0005389_reproductive_system_phenotype | 1.84692763 |
26 | MP0003786_premature_aging | 1.83920147 |
27 | MP0006036_abnormal_mitochondrial_physio | 1.82565776 |
28 | MP0009333_abnormal_splenocyte_physiolog | 1.75496732 |
29 | MP0003123_paternal_imprinting | 1.74473570 |
30 | MP0008058_abnormal_DNA_repair | 1.73226288 |
31 | MP0001730_embryonic_growth_arrest | 1.70493066 |
32 | MP0001919_abnormal_reproductive_system | 1.69256610 |
33 | MP0000750_abnormal_muscle_regeneration | 1.65813180 |
34 | MP0000678_abnormal_parathyroid_gland | 1.59206781 |
35 | MP0006276_abnormal_autonomic_nervous | 1.56384987 |
36 | MP0004133_heterotaxia | 1.54948764 |
37 | MP0002009_preneoplasia | 1.54320953 |
38 | MP0000747_muscle_weakness | 1.53987509 |
39 | MP0000749_muscle_degeneration | 1.53976289 |
40 | MP0003283_abnormal_digestive_organ | 1.50975752 |
41 | MP0000350_abnormal_cell_proliferation | 1.49903270 |
42 | MP0000003_abnormal_adipose_tissue | 1.49873291 |
43 | MP0004084_abnormal_cardiac_muscle | 1.48142912 |
44 | MP0003186_abnormal_redox_activity | 1.46352124 |
45 | MP0000759_abnormal_skeletal_muscle | 1.38366196 |
46 | MP0002090_abnormal_vision | 1.36049235 |
47 | MP0008260_abnormal_autophagy | 1.35990505 |
48 | MP0001697_abnormal_embryo_size | 1.33431896 |
49 | MP0000372_irregular_coat_pigmentation | 1.30374050 |
50 | MP0008789_abnormal_olfactory_epithelium | 1.30161053 |
51 | MP0002735_abnormal_chemical_nociception | 1.29270483 |
52 | MP0005377_hearing/vestibular/ear_phenot | 1.25513677 |
53 | MP0003878_abnormal_ear_physiology | 1.25513677 |
54 | MP0004185_abnormal_adipocyte_glucose | 1.21265531 |
55 | MP0001542_abnormal_bone_strength | 1.21258084 |
56 | MP0003329_amyloid_beta_deposits | 1.20620952 |
57 | MP0004510_myositis | 1.19886808 |
58 | MP0005623_abnormal_meninges_morphology | 1.19348837 |
59 | MP0000537_abnormal_urethra_morphology | 1.18834477 |
60 | MP0000858_altered_metastatic_potential | 1.18647591 |
61 | MP0005257_abnormal_intraocular_pressure | 1.18554574 |
62 | MP0003705_abnormal_hypodermis_morpholog | 1.18431846 |
63 | MP0005171_absent_coat_pigmentation | 1.18007024 |
64 | MP0002653_abnormal_ependyma_morphology | 1.17064003 |
65 | MP0000681_abnormal_thyroid_gland | 1.16278258 |
66 | MP0005375_adipose_tissue_phenotype | 1.13119089 |
67 | MP0000751_myopathy | 1.11299295 |
68 | MP0005330_cardiomyopathy | 1.10917334 |
69 | MP0002080_prenatal_lethality | 1.10775268 |
70 | MP0002736_abnormal_nociception_after | 1.08127046 |
71 | MP0004859_abnormal_synaptic_plasticity | 1.07639728 |
72 | MP0005083_abnormal_biliary_tract | 1.07360962 |
73 | MP0002249_abnormal_larynx_morphology | 1.07206723 |
74 | MP0002269_muscular_atrophy | 1.06021673 |
75 | MP0000343_altered_response_to | 1.05822673 |
76 | MP0001346_abnormal_lacrimal_gland | 1.04024759 |
77 | MP0003191_abnormal_cellular_cholesterol | 1.03518728 |
78 | MP0001905_abnormal_dopamine_level | 1.02450095 |
79 | MP0001661_extended_life_span | 1.02303499 |
80 | MP0005380_embryogenesis_phenotype | 0.99699019 |
81 | MP0001672_abnormal_embryogenesis/_devel | 0.99699019 |
82 | MP0001849_ear_inflammation | 0.98925574 |
83 | MP0009672_abnormal_birth_weight | 0.97848478 |
84 | MP0002106_abnormal_muscle_physiology | 0.97130582 |
85 | MP0001853_heart_inflammation | 0.95051787 |
86 | MP0004087_abnormal_muscle_fiber | 0.94789308 |
87 | MP0010030_abnormal_orbit_morphology | 0.94740372 |
88 | MP0000313_abnormal_cell_death | 0.94304984 |
89 | MP0005666_abnormal_adipose_tissue | 0.94179437 |
90 | MP0003075_altered_response_to | 0.93144843 |
91 | MP0002163_abnormal_gland_morphology | 0.92793572 |
92 | MP0005266_abnormal_metabolism | 0.92550162 |
93 | MP0002837_dystrophic_cardiac_calcinosis | 0.92420599 |
94 | MP0002734_abnormal_mechanical_nocicepti | 0.91697354 |
95 | MP0005499_abnormal_olfactory_system | 0.91484861 |
96 | MP0005394_taste/olfaction_phenotype | 0.91484861 |
97 | MP0003984_embryonic_growth_retardation | 0.89975665 |
98 | MP0001727_abnormal_embryo_implantation | 0.89441896 |
99 | MP0001968_abnormal_touch/_nociception | 0.89258434 |
100 | MP0005165_increased_susceptibility_to | 0.89017963 |
101 | MP0002132_abnormal_respiratory_system | 0.88510961 |
102 | MP0002796_impaired_skin_barrier | 0.88480389 |
103 | MP0001970_abnormal_pain_threshold | 0.88046475 |
104 | MP0005384_cellular_phenotype | 0.88011754 |
105 | MP0009053_abnormal_anal_canal | 0.87874899 |
106 | MP0009046_muscle_twitch | 0.87508753 |
107 | MP0000733_abnormal_muscle_development | 0.86610874 |
108 | MP0002088_abnormal_embryonic_growth/wei | 0.85853882 |
109 | MP0001348_abnormal_lacrimal_gland | 0.85713987 |
110 | MP0003119_abnormal_digestive_system | 0.85018717 |
111 | MP0008770_decreased_survivor_rate | 0.82536587 |
112 | MP0004145_abnormal_muscle_electrophysio | 0.80278366 |
113 | MP0003879_abnormal_hair_cell | 0.79888622 |
114 | MP0002332_abnormal_exercise_endurance | 0.79267157 |
115 | MP0000049_abnormal_middle_ear | 0.79090805 |
116 | MP0008057_abnormal_DNA_replication | 0.76094013 |
117 | MP0002733_abnormal_thermal_nociception | 0.75316102 |
118 | MP0002970_abnormal_white_adipose | 0.75116615 |
119 | MP0003221_abnormal_cardiomyocyte_apopto | 0.75057300 |
120 | MP0003137_abnormal_impulse_conducting | 0.74259134 |
121 | MP0003938_abnormal_ear_development | 0.74153390 |
122 | MP0002019_abnormal_tumor_incidence | 0.73862495 |
123 | MP0002184_abnormal_innervation | 0.73299158 |
124 | MP0004147_increased_porphyrin_level | 0.71471705 |
125 | MP0002085_abnormal_embryonic_tissue | 0.69364512 |
126 | MP0004811_abnormal_neuron_physiology | 0.69087607 |
127 | MP0001243_abnormal_dermal_layer | 0.67628422 |
128 | MP0004858_abnormal_nervous_system | 0.67371564 |
129 | MP0003656_abnormal_erythrocyte_physiolo | 0.67110287 |
130 | MP0005621_abnormal_cell_physiology | 0.66856933 |
131 | MP0004036_abnormal_muscle_relaxation | 0.66563404 |
132 | MP0005369_muscle_phenotype | 0.66415890 |
133 | MP0002089_abnormal_postnatal_growth/wei | 0.65698004 |
134 | MP0004142_abnormal_muscle_tone | 0.65408572 |
135 | MP0002060_abnormal_skin_morphology | 0.62089673 |
136 | MP0001145_abnormal_male_reproductive | 0.61887379 |
137 | MP0005395_other_phenotype | 0.61769289 |
138 | MP0000428_abnormal_craniofacial_morphol | 0.61029350 |
139 | MP0005508_abnormal_skeleton_morphology | 0.60609637 |
140 | MP0004197_abnormal_fetal_growth/weight/ | 0.58813505 |
141 | MP0000490_abnormal_crypts_of | 0.58754719 |
142 | MP0000467_abnormal_esophagus_morphology | 0.58264480 |
143 | MP0005397_hematopoietic_system_phenotyp | 0.58128456 |
144 | MP0001545_abnormal_hematopoietic_system | 0.58128456 |
145 | MP0005501_abnormal_skin_physiology | 0.57645669 |
146 | MP0002169_no_abnormal_phenotype | 0.56507314 |
147 | MP0003880_abnormal_central_pattern | 0.56120631 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Elevated erythrocyte sedimentation rate (HP:0003565) | 6.09005383 |
2 | Conjugated hyperbilirubinemia (HP:0002908) | 5.99969684 |
3 | Peritonitis (HP:0002586) | 5.55900428 |
4 | Progressive external ophthalmoplegia (HP:0000590) | 5.26146038 |
5 | Neuroendocrine neoplasm (HP:0100634) | 4.10812974 |
6 | Progressive cerebellar ataxia (HP:0002073) | 4.02671822 |
7 | Cholecystitis (HP:0001082) | 3.96005465 |
8 | Abnormal gallbladder physiology (HP:0012438) | 3.96005465 |
9 | Acute necrotizing encephalopathy (HP:0006965) | 3.82597413 |
10 | Increased hepatocellular lipid droplets (HP:0006565) | 3.82227656 |
11 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.79505638 |
12 | Hepatocellular necrosis (HP:0001404) | 3.73529821 |
13 | Insidious onset (HP:0003587) | 3.72820698 |
14 | Termporal pattern (HP:0011008) | 3.72820698 |
15 | Breast hypoplasia (HP:0003187) | 3.72649373 |
16 | Ragged-red muscle fibers (HP:0003200) | 3.70771881 |
17 | Mitochondrial inheritance (HP:0001427) | 3.63470938 |
18 | Cerebral hypomyelination (HP:0006808) | 3.47089835 |
19 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.47058120 |
20 | Lipid accumulation in hepatocytes (HP:0006561) | 3.34371109 |
21 | Renal tubular acidosis (HP:0001947) | 3.26724308 |
22 | Pancreatic cysts (HP:0001737) | 3.26439554 |
23 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 3.25696509 |
24 | Hepatic necrosis (HP:0002605) | 3.22053531 |
25 | Reticulocytopenia (HP:0001896) | 3.20942637 |
26 | Nephrogenic diabetes insipidus (HP:0009806) | 3.19954611 |
27 | Increased CSF lactate (HP:0002490) | 3.17065482 |
28 | Myopathic facies (HP:0002058) | 3.12906574 |
29 | Pheochromocytoma (HP:0002666) | 3.11802974 |
30 | Carpal bone hypoplasia (HP:0001498) | 3.05233003 |
31 | Broad distal phalanx of finger (HP:0009836) | 3.03857146 |
32 | Central scotoma (HP:0000603) | 3.03335320 |
33 | Achilles tendon contracture (HP:0001771) | 3.02810068 |
34 | Acute encephalopathy (HP:0006846) | 3.02514732 |
35 | Increased serum lactate (HP:0002151) | 3.02464714 |
36 | Shoulder girdle muscle weakness (HP:0003547) | 3.01245903 |
37 | Renal Fanconi syndrome (HP:0001994) | 2.98207473 |
38 | Congenital, generalized hypertrichosis (HP:0004540) | 2.93762735 |
39 | Dyschromatopsia (HP:0007641) | 2.85843204 |
40 | Exertional dyspnea (HP:0002875) | 2.82809800 |
41 | Increased intramyocellular lipid droplets (HP:0012240) | 2.80755033 |
42 | 3-Methylglutaconic aciduria (HP:0003535) | 2.80444933 |
43 | Progressive macrocephaly (HP:0004481) | 2.79636507 |
44 | External ophthalmoplegia (HP:0000544) | 2.77874687 |
45 | Renal tubular dysfunction (HP:0000124) | 2.76935301 |
46 | Distal lower limb muscle weakness (HP:0009053) | 2.75732368 |
47 | Microvesicular hepatic steatosis (HP:0001414) | 2.75537386 |
48 | Rimmed vacuoles (HP:0003805) | 2.73860514 |
49 | Exercise intolerance (HP:0003546) | 2.73425474 |
50 | Increased connective tissue (HP:0009025) | 2.73361824 |
51 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.62961875 |
52 | Pelvic girdle muscle weakness (HP:0003749) | 2.60896287 |
53 | Abnormality of the peritoneum (HP:0002585) | 2.57785626 |
54 | Distal upper limb amyotrophy (HP:0007149) | 2.56478622 |
55 | Upper limb amyotrophy (HP:0009129) | 2.56478622 |
56 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.55734750 |
57 | Vertebral compression fractures (HP:0002953) | 2.54597916 |
58 | Type I transferrin isoform profile (HP:0003642) | 2.51829810 |
59 | Hyperacusis (HP:0010780) | 2.50434194 |
60 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.48643681 |
61 | Abnormality of the Achilles tendon (HP:0005109) | 2.47827267 |
62 | Insomnia (HP:0100785) | 2.45801194 |
63 | Hypertensive crisis (HP:0100735) | 2.44009334 |
64 | Birth length less than 3rd percentile (HP:0003561) | 2.42828778 |
65 | Hypokinesia (HP:0002375) | 2.41896153 |
66 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.41285366 |
67 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.41285366 |
68 | Aplastic anemia (HP:0001915) | 2.40312317 |
69 | Optic disc pallor (HP:0000543) | 2.39604985 |
70 | Increased serum pyruvate (HP:0003542) | 2.38876670 |
71 | Abnormality of glycolysis (HP:0004366) | 2.38876670 |
72 | Abnormality of the umbilical cord (HP:0010881) | 2.36586096 |
73 | Prolonged neonatal jaundice (HP:0006579) | 2.35900746 |
74 | Abnormal number of erythroid precursors (HP:0012131) | 2.34262292 |
75 | Abnormality of the musculature of the pelvis (HP:0001469) | 2.32628418 |
76 | Abnormality of the hip-girdle musculature (HP:0001445) | 2.32628418 |
77 | Increased muscle lipid content (HP:0009058) | 2.32413069 |
78 | Rough bone trabeculation (HP:0100670) | 2.31454048 |
79 | Lactic acidosis (HP:0003128) | 2.30057184 |
80 | Emotional lability (HP:0000712) | 2.29624581 |
81 | Neoplasm of the peripheral nervous system (HP:0100007) | 2.29390528 |
82 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 2.28356276 |
83 | Opisthotonus (HP:0002179) | 2.24396590 |
84 | Fasciculations (HP:0002380) | 2.23760924 |
85 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.23723158 |
86 | Hand muscle atrophy (HP:0009130) | 2.23717751 |
87 | Patellar aplasia (HP:0006443) | 2.22778807 |
88 | CNS demyelination (HP:0007305) | 2.20350532 |
89 | Chromsome breakage (HP:0040012) | 2.19072052 |
90 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.18427797 |
91 | Respiratory difficulties (HP:0002880) | 2.18124787 |
92 | Macrocytic anemia (HP:0001972) | 2.16997055 |
93 | Generalized amyotrophy (HP:0003700) | 2.16473727 |
94 | Distal lower limb amyotrophy (HP:0008944) | 2.16365934 |
95 | Limb dystonia (HP:0002451) | 2.15023902 |
96 | Abnormality of skeletal muscle fiber size (HP:0012084) | 2.14719136 |
97 | Abnormal trabecular bone morphology (HP:0100671) | 2.14675805 |
98 | Stridor (HP:0010307) | 2.14501640 |
99 | Increased variability in muscle fiber diameter (HP:0003557) | 2.14297483 |
100 | Progressive sensorineural hearing impairment (HP:0000408) | 2.14264670 |
101 | Cholelithiasis (HP:0001081) | 2.13984648 |
102 | Multiple enchondromatosis (HP:0005701) | 2.12244150 |
103 | Progressive muscle weakness (HP:0003323) | 2.09277536 |
104 | Selective tooth agenesis (HP:0001592) | 2.07754524 |
105 | Difficulty climbing stairs (HP:0003551) | 2.07494481 |
106 | Pancreatic fibrosis (HP:0100732) | 2.06764851 |
107 | Degeneration of anterior horn cells (HP:0002398) | 2.06489993 |
108 | Abnormality of the anterior horn cell (HP:0006802) | 2.06489993 |
109 | Reduced subcutaneous adipose tissue (HP:0003758) | 2.06075043 |
110 | Areflexia of lower limbs (HP:0002522) | 2.04226405 |
111 | Horizontal nystagmus (HP:0000666) | 2.04176465 |
112 | Trismus (HP:0000211) | 2.03652724 |
113 | Ureteral duplication (HP:0000073) | 2.03652663 |
114 | Lissencephaly (HP:0001339) | 2.03412327 |
115 | Abnormality of pain sensation (HP:0010832) | 2.02634971 |
116 | Impaired pain sensation (HP:0007328) | 2.02634971 |
117 | Cerebral edema (HP:0002181) | 2.02482309 |
118 | Axonal loss (HP:0003447) | 2.01521782 |
119 | Rhabdomyolysis (HP:0003201) | 2.01257455 |
120 | Premature rupture of membranes (HP:0001788) | 2.01079929 |
121 | Respiratory failure (HP:0002878) | 2.00959527 |
122 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.99475100 |
123 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.99475100 |
124 | Abnormal protein glycosylation (HP:0012346) | 1.99475100 |
125 | Abnormal glycosylation (HP:0012345) | 1.99475100 |
126 | Delusions (HP:0000746) | 1.98688681 |
127 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.98577660 |
128 | Pallor (HP:0000980) | 1.97598999 |
129 | Entropion (HP:0000621) | 1.96595464 |
130 | Long palpebral fissure (HP:0000637) | 1.96247162 |
131 | Testicular atrophy (HP:0000029) | 1.94218944 |
132 | Horseshoe kidney (HP:0000085) | 1.93750735 |
133 | True hermaphroditism (HP:0010459) | 1.93211110 |
134 | Absent radius (HP:0003974) | 1.92390866 |
135 | Tinnitus (HP:0000360) | 1.91651322 |
136 | Microretrognathia (HP:0000308) | 1.91539274 |
137 | Scotoma (HP:0000575) | 1.89936892 |
138 | Myokymia (HP:0002411) | 1.89681434 |
139 | Abnormality of the gallbladder (HP:0005264) | 1.88325170 |
140 | Upper limb muscle weakness (HP:0003484) | 1.87324802 |
141 | Annular pancreas (HP:0001734) | 1.86547202 |
142 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.85887180 |
143 | Abnormal gallbladder morphology (HP:0012437) | 1.82825760 |
144 | Abnormal umbilical cord blood vessels (HP:0011403) | 1.82556117 |
145 | Single umbilical artery (HP:0001195) | 1.82556117 |
146 | Abnormality of the fetal cardiovascular system (HP:0010948) | 1.82556117 |
147 | Secondary amenorrhea (HP:0000869) | 1.81770461 |
148 | Reduced antithrombin III activity (HP:0001976) | 1.80826812 |
149 | Progressive microcephaly (HP:0000253) | 1.80754662 |
150 | Spastic paraparesis (HP:0002313) | 1.79457004 |
151 | Abnormalities of placenta or umbilical cord (HP:0001194) | 1.78311644 |
152 | Abnormality of glycolipid metabolism (HP:0010969) | 1.78032750 |
153 | Abnormality of liposaccharide metabolism (HP:0010968) | 1.78032750 |
154 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 1.78032750 |
155 | Death in infancy (HP:0001522) | 1.73147451 |
156 | Overriding aorta (HP:0002623) | 1.71847171 |
157 | Truncus arteriosus (HP:0001660) | 1.71788242 |
158 | Athetosis (HP:0002305) | 1.71662526 |
159 | Ulnar bowing (HP:0003031) | 1.70447955 |
160 | Retinal dysplasia (HP:0007973) | 1.69954531 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BUB1 | 4.93155995 |
2 | NME2 | 4.78312463 |
3 | MAP3K11 | 4.37169933 |
4 | VRK2 | 4.26758133 |
5 | TESK2 | 3.10533331 |
6 | WEE1 | 2.97151682 |
7 | SMG1 | 2.83507450 |
8 | TLK1 | 2.71776620 |
9 | TESK1 | 2.49182802 |
10 | SRPK1 | 2.33939026 |
11 | NME1 | 2.31523542 |
12 | NUAK1 | 2.31136943 |
13 | PIM2 | 2.30721432 |
14 | EIF2AK1 | 2.29751636 |
15 | LIMK1 | 2.28396097 |
16 | ARAF | 2.22535505 |
17 | DYRK3 | 2.19563749 |
18 | STK16 | 1.97962839 |
19 | TSSK6 | 1.95556209 |
20 | RPS6KA4 | 1.84755619 |
21 | NEK1 | 1.83387398 |
22 | TRIB3 | 1.79306074 |
23 | PLK4 | 1.74926663 |
24 | TAOK2 | 1.72905213 |
25 | BRSK1 | 1.72096602 |
26 | ERN1 | 1.62450753 |
27 | BRAF | 1.59372784 |
28 | ICK | 1.57626553 |
29 | AURKA | 1.50459803 |
30 | KDR | 1.49148961 |
31 | PLK3 | 1.47677618 |
32 | EPHA2 | 1.40869424 |
33 | PRKD3 | 1.35729800 |
34 | VRK1 | 1.32900036 |
35 | MAP2K2 | 1.32002144 |
36 | PLK1 | 1.25796605 |
37 | EPHB2 | 1.23902062 |
38 | NEK9 | 1.23846248 |
39 | EIF2AK3 | 1.22450994 |
40 | PBK | 1.20709965 |
41 | NEK2 | 1.15477283 |
42 | CSNK1G3 | 1.07622983 |
43 | MAP3K8 | 1.07143916 |
44 | EEF2K | 1.03026400 |
45 | TTN | 0.99820682 |
46 | DYRK2 | 0.97461777 |
47 | PLK2 | 0.95153951 |
48 | SIK1 | 0.93253212 |
49 | LATS2 | 0.92045689 |
50 | ZAK | 0.91507541 |
51 | PDK2 | 0.90648236 |
52 | CHEK2 | 0.89975267 |
53 | TTK | 0.88942484 |
54 | AURKB | 0.87486488 |
55 | BRSK2 | 0.85538718 |
56 | LRRK2 | 0.84857390 |
57 | LMTK2 | 0.84155903 |
58 | MARK1 | 0.83638730 |
59 | PRPF4B | 0.83598130 |
60 | GRK5 | 0.81794957 |
61 | SIK3 | 0.81483122 |
62 | AKT3 | 0.79748922 |
63 | PAK1 | 0.79383444 |
64 | CDK8 | 0.78211241 |
65 | CSNK1A1L | 0.77362076 |
66 | PAK6 | 0.75076645 |
67 | CSNK2A2 | 0.74273683 |
68 | PRKCI | 0.73575341 |
69 | CDC7 | 0.72156742 |
70 | ABL2 | 0.72051303 |
71 | CCNB1 | 0.71864807 |
72 | MINK1 | 0.67718085 |
73 | AKT2 | 0.66777864 |
74 | DAPK3 | 0.66552213 |
75 | MAPK11 | 0.66116765 |
76 | CDK14 | 0.65791472 |
77 | TBK1 | 0.64959305 |
78 | CSNK2A1 | 0.60781883 |
79 | CDK7 | 0.60648359 |
80 | BCKDK | 0.60505113 |
81 | CSNK1G2 | 0.59927256 |
82 | CDK4 | 0.59893550 |
83 | CAMK2G | 0.56436931 |
84 | MYLK | 0.56123245 |
85 | RPS6KA5 | 0.54368056 |
86 | IRAK3 | 0.54163754 |
87 | MOS | 0.53215411 |
88 | PTK2 | 0.53020574 |
89 | PINK1 | 0.51135207 |
90 | MKNK1 | 0.50689930 |
91 | CAMK2B | 0.49932192 |
92 | PDK3 | 0.49664884 |
93 | PDK4 | 0.49664884 |
94 | MAP2K3 | 0.48833886 |
95 | BLK | 0.48466902 |
96 | STK10 | 0.48192723 |
97 | OBSCN | 0.46649599 |
98 | CHEK1 | 0.46225869 |
99 | PNCK | 0.46137660 |
100 | SCYL2 | 0.45216246 |
101 | MAP2K7 | 0.44914612 |
102 | DAPK1 | 0.44254722 |
103 | PAK4 | 0.43892346 |
104 | CSNK1G1 | 0.43326401 |
105 | BMX | 0.42933632 |
106 | MKNK2 | 0.42767231 |
107 | ILK | 0.42312478 |
108 | MAP3K12 | 0.42248530 |
109 | STK4 | 0.40284458 |
110 | CDK18 | 0.40226735 |
111 | PRKCG | 0.40136033 |
112 | RPS6KA6 | 0.39560401 |
113 | MAP3K3 | 0.39079961 |
114 | RPS6KB2 | 0.38708398 |
115 | RPS6KC1 | 0.38203834 |
116 | RPS6KL1 | 0.38203834 |
117 | MAP2K1 | 0.37949051 |
118 | CDK15 | 0.37004571 |
119 | CAMK2D | 0.36025043 |
120 | TAOK1 | 0.35632622 |
121 | IRAK2 | 0.35364186 |
122 | CDK11A | 0.34853385 |
123 | ATR | 0.34524635 |
124 | MAPKAPK3 | 0.34431794 |
125 | SIK2 | 0.33910357 |
126 | PRKG2 | 0.33858417 |
127 | CDK19 | 0.32907801 |
128 | MTOR | 0.31389614 |
129 | CSNK1E | 0.31254975 |
130 | PRKD2 | 0.30817847 |
131 | NTRK1 | 0.30013078 |
132 | CDK2 | 0.28979177 |
133 | PRKCD | 0.28556873 |
134 | PHKG2 | 0.28334911 |
135 | PHKG1 | 0.28334911 |
136 | MST1R | 0.28315539 |
137 | UHMK1 | 0.28240201 |
138 | CSNK1A1 | 0.27208726 |
139 | GRK6 | 0.26026564 |
140 | CASK | 0.24268653 |
141 | CAMKK1 | 0.23645542 |
142 | BCR | 0.23313179 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Proteasome_Homo sapiens_hsa03050 | 5.34137479 |
2 | Ribosome_Homo sapiens_hsa03010 | 5.01743139 |
3 | RNA polymerase_Homo sapiens_hsa03020 | 3.74003690 |
4 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.55561805 |
5 | DNA replication_Homo sapiens_hsa03030 | 3.55427481 |
6 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 3.42364701 |
7 | Parkinsons disease_Homo sapiens_hsa05012 | 3.22253396 |
8 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.91327094 |
9 | Mismatch repair_Homo sapiens_hsa03430 | 2.83947929 |
10 | Spliceosome_Homo sapiens_hsa03040 | 2.72708312 |
11 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.56681465 |
12 | Huntingtons disease_Homo sapiens_hsa05016 | 2.49493777 |
13 | RNA transport_Homo sapiens_hsa03013 | 2.31504701 |
14 | Sulfur relay system_Homo sapiens_hsa04122 | 2.12452707 |
15 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.11524183 |
16 | Alzheimers disease_Homo sapiens_hsa05010 | 2.10141602 |
17 | Base excision repair_Homo sapiens_hsa03410 | 1.98838367 |
18 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.77934659 |
19 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.70632362 |
20 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.66955401 |
21 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.63007726 |
22 | Homologous recombination_Homo sapiens_hsa03440 | 1.51972865 |
23 | Cell cycle_Homo sapiens_hsa04110 | 1.51025682 |
24 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.50472039 |
25 | Purine metabolism_Homo sapiens_hsa00230 | 1.39893736 |
26 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.33625760 |
27 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.17165541 |
28 | Basal transcription factors_Homo sapiens_hsa03022 | 1.14651327 |
29 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.14438141 |
30 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.11839902 |
31 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.11598229 |
32 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.09169331 |
33 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.08543511 |
34 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.01729576 |
35 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.99586494 |
36 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.98327338 |
37 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.96652647 |
38 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.96240214 |
39 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.95097118 |
40 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.94994472 |
41 | Carbon metabolism_Homo sapiens_hsa01200 | 0.94168414 |
42 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.89706614 |
43 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.87588456 |
44 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.85558962 |
45 | Other glycan degradation_Homo sapiens_hsa00511 | 0.83929859 |
46 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.80735567 |
47 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.80130042 |
48 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.79847431 |
49 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.79746288 |
50 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.78956210 |
51 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.78377368 |
52 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.77570981 |
53 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.77333921 |
54 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.73701120 |
55 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.73468444 |
56 | RNA degradation_Homo sapiens_hsa03018 | 0.73267495 |
57 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.70922065 |
58 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.68662374 |
59 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.67882111 |
60 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.65137327 |
61 | Protein export_Homo sapiens_hsa03060 | 0.64972365 |
62 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.63361982 |
63 | Legionellosis_Homo sapiens_hsa05134 | 0.58441149 |
64 | Metabolic pathways_Homo sapiens_hsa01100 | 0.58093309 |
65 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.56991907 |
66 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.56677751 |
67 | Lysosome_Homo sapiens_hsa04142 | 0.54764116 |
68 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.54277503 |
69 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.51574392 |
70 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.51559660 |
71 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.50893634 |
72 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.47735620 |
73 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.47084337 |
74 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.46616340 |
75 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.44435305 |
76 | Phagosome_Homo sapiens_hsa04145 | 0.43989440 |
77 | Thyroid cancer_Homo sapiens_hsa05216 | 0.42963744 |
78 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.42734780 |
79 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.36649838 |
80 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.36192414 |
81 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.35868076 |
82 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.35819955 |
83 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.35319034 |
84 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.32365971 |
85 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.31988952 |
86 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.31612781 |
87 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.30648615 |
88 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.30417229 |
89 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.29629217 |
90 | Peroxisome_Homo sapiens_hsa04146 | 0.27303975 |
91 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.26839878 |
92 | Galactose metabolism_Homo sapiens_hsa00052 | 0.26786819 |
93 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.24520088 |
94 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.23755427 |
95 | Apoptosis_Homo sapiens_hsa04210 | 0.23406957 |
96 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.21083220 |
97 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.20622712 |
98 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.20293122 |
99 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.19691188 |
100 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.17382289 |
101 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.16580511 |
102 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.16578403 |
103 | Bladder cancer_Homo sapiens_hsa05219 | 0.16528086 |
104 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.16378568 |
105 | Allograft rejection_Homo sapiens_hsa05330 | 0.13845750 |
106 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.13358182 |
107 | Salmonella infection_Homo sapiens_hsa05132 | 0.12916890 |
108 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.10964334 |
109 | Prion diseases_Homo sapiens_hsa05020 | 0.10847096 |
110 | Asthma_Homo sapiens_hsa05310 | 0.10577964 |
111 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.09117405 |
112 | Endocytosis_Homo sapiens_hsa04144 | 0.09075067 |
113 | Lysine degradation_Homo sapiens_hsa00310 | 0.08763535 |
114 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.08285667 |
115 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.07971351 |
116 | Alcoholism_Homo sapiens_hsa05034 | 0.07217365 |
117 | HTLV-I infection_Homo sapiens_hsa05166 | 0.06642328 |
118 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.06560954 |
119 | Shigellosis_Homo sapiens_hsa05131 | 0.03561247 |
120 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.01866352 |
121 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.01616260 |
122 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | -0.0189112 |
123 | Type I diabetes mellitus_Homo sapiens_hsa04940 | -0.0042648 |