CCDC127

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle docking involved in exocytosis (GO:0016081)5.24962241
2behavioral response to nicotine (GO:0035095)4.53215329
3regulation of synaptic vesicle exocytosis (GO:2000300)4.22508033
4synaptic vesicle exocytosis (GO:0016079)4.20953603
5regulation of short-term neuronal synaptic plasticity (GO:0048172)4.12600444
6protein localization to synapse (GO:0035418)4.06538788
7presynaptic membrane assembly (GO:0097105)4.04966741
8glutamate secretion (GO:0014047)3.93964945
9regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)3.81253471
10regulation of dopamine uptake involved in synaptic transmission (GO:0051584)3.81253471
11postsynaptic membrane organization (GO:0001941)3.80055329
12regulation of synaptic vesicle transport (GO:1902803)3.76002010
13reflex (GO:0060004)3.74064135
14neuronal action potential propagation (GO:0019227)3.72489488
15piRNA metabolic process (GO:0034587)3.71690206
16neuron cell-cell adhesion (GO:0007158)3.71105966
17regulation of neurotransmitter uptake (GO:0051580)3.70437862
18presynaptic membrane organization (GO:0097090)3.61335972
19artery development (GO:0060840)3.59733426
20vocalization behavior (GO:0071625)3.55476883
21positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.51201815
22outer ear morphogenesis (GO:0042473)3.49522530
23cellular biogenic amine catabolic process (GO:0042402)3.49346736
24amine catabolic process (GO:0009310)3.49346736
25synaptic vesicle maturation (GO:0016188)3.49044610
26positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)3.44954129
27detection of calcium ion (GO:0005513)3.44829241
28cilium or flagellum-dependent cell motility (GO:0001539)3.42429333
29peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)3.41975389
30peristalsis (GO:0030432)3.41657475
31detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.37804899
32indole-containing compound catabolic process (GO:0042436)3.32596536
33indolalkylamine catabolic process (GO:0046218)3.32596536
34tryptophan catabolic process (GO:0006569)3.32596536
35regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.31961941
36regulation of hippo signaling (GO:0035330)3.31877631
37regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.30795800
38inositol phosphate catabolic process (GO:0071545)3.26044333
39epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.25516439
40L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.21658049
41musculoskeletal movement (GO:0050881)3.20968115
42multicellular organismal movement (GO:0050879)3.20968115
43cerebellar Purkinje cell differentiation (GO:0021702)3.20923994
44regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.18377015
45axoneme assembly (GO:0035082)3.16456551
46respiratory chain complex IV assembly (GO:0008535)3.15938358
47behavioral response to cocaine (GO:0048148)3.15813148
48cornea development in camera-type eye (GO:0061303)3.14505129
49negative regulation of sodium ion transport (GO:0010766)3.13662576
50membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.13185952
51epithelial cilium movement (GO:0003351)3.11999336
52regulation of synapse structural plasticity (GO:0051823)3.11637536
53cilium movement (GO:0003341)3.11566030
54ubiquinone biosynthetic process (GO:0006744)3.11341850
55protein localization to cilium (GO:0061512)3.11335779
56positive regulation of synapse maturation (GO:0090129)3.11104441
57positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.10547943
58locomotory exploration behavior (GO:0035641)3.10037686
59neurotransmitter secretion (GO:0007269)3.09823296
60regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)3.03466483
61regulation of glutamate receptor signaling pathway (GO:1900449)3.01622654
62negative regulation of dendrite morphogenesis (GO:0050774)2.98964644
63kynurenine metabolic process (GO:0070189)2.98122877
64striatum development (GO:0021756)2.98103577
65neural tube formation (GO:0001841)2.97762284
66axonemal dynein complex assembly (GO:0070286)2.97492821
67regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.97218873
68ubiquinone metabolic process (GO:0006743)2.97122969
69DNA methylation involved in gamete generation (GO:0043046)2.96615033
70axonal fasciculation (GO:0007413)2.95681223
71neuron-neuron synaptic transmission (GO:0007270)2.94692908
72regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.94118927
73regulation of cell communication by electrical coupling (GO:0010649)2.93740392
74detection of light stimulus involved in visual perception (GO:0050908)2.93290900
75detection of light stimulus involved in sensory perception (GO:0050962)2.93290900
76indolalkylamine metabolic process (GO:0006586)2.92687811
77motile cilium assembly (GO:0044458)2.90552375
78meiotic chromosome segregation (GO:0045132)2.88972397
79regulation of neurotransmitter secretion (GO:0046928)2.88338356
80cochlea development (GO:0090102)2.87703071
81regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)2.87518837
82mitochondrial respiratory chain complex I assembly (GO:0032981)2.85580502
83NADH dehydrogenase complex assembly (GO:0010257)2.85580502
84mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.85580502
85activation of protein kinase A activity (GO:0034199)2.84730312
86protein polyglutamylation (GO:0018095)2.83668668
87synaptic transmission, glutamatergic (GO:0035249)2.82916658
88regulation of neuronal synaptic plasticity (GO:0048168)2.79931004
89cilium organization (GO:0044782)2.79632475
90protein complex biogenesis (GO:0070271)2.79544151
91gamma-aminobutyric acid signaling pathway (GO:0007214)2.79197550
92L-methionine salvage (GO:0071267)2.78111099
93L-methionine biosynthetic process (GO:0071265)2.78111099
94amino acid salvage (GO:0043102)2.78111099
95positive regulation of membrane potential (GO:0045838)2.77994789
96neuronal action potential (GO:0019228)2.77607105
97neurotransmitter-gated ion channel clustering (GO:0072578)2.76070137
98cilium assembly (GO:0042384)2.75738602
99female mating behavior (GO:0060180)2.72874084
100innervation (GO:0060384)2.72833399
101prepulse inhibition (GO:0060134)2.72007829
102Golgi transport vesicle coating (GO:0048200)2.71929647
103COPI coating of Golgi vesicle (GO:0048205)2.71929647
104inositol phosphate dephosphorylation (GO:0046855)2.71493890
105phosphorylated carbohydrate dephosphorylation (GO:0046838)2.71493890
106positive regulation of synaptic transmission, GABAergic (GO:0032230)2.69547199
107exploration behavior (GO:0035640)2.68977144
108transmission of nerve impulse (GO:0019226)2.68450074
109tryptophan metabolic process (GO:0006568)2.67082788
110negative regulation of synaptic transmission, GABAergic (GO:0032229)2.65706506
111neuron recognition (GO:0008038)2.65277598
112positive regulation of neurotransmitter transport (GO:0051590)2.64828902
113facial nerve structural organization (GO:0021612)2.64029361
114regulation of long-term neuronal synaptic plasticity (GO:0048169)2.63629429
115retinal cone cell development (GO:0046549)2.61968217
116gamma-aminobutyric acid transport (GO:0015812)2.61745036
117kidney morphogenesis (GO:0060993)2.61425627
118regulation of neurotransmitter transport (GO:0051588)2.61226923
119mitochondrial respiratory chain complex assembly (GO:0033108)2.60112657
120response to pheromone (GO:0019236)2.59569802
121primary amino compound metabolic process (GO:1901160)2.59408936
122auditory receptor cell stereocilium organization (GO:0060088)2.59192881
123mannosylation (GO:0097502)2.58543965
124negative regulation of cation channel activity (GO:2001258)2.58476386
125indole-containing compound metabolic process (GO:0042430)2.58255226
126regulation of synaptic transmission, dopaminergic (GO:0032225)2.57432763
127cerebellum development (GO:0021549)2.56336322
128transferrin transport (GO:0033572)2.56260526
129positive regulation of neurotransmitter secretion (GO:0001956)2.55974411
130cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.55518580
131long-term synaptic potentiation (GO:0060291)2.54767018
132cilium morphogenesis (GO:0060271)2.54425467
133long-term memory (GO:0007616)2.53546785
134adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.53465092
135cerebellar granule cell differentiation (GO:0021707)2.53092612
136positive regulation of action potential (GO:0045760)2.52342401
137intraciliary transport (GO:0042073)2.51308971
138startle response (GO:0001964)2.51263641
139regulation of mitochondrial fission (GO:0090140)2.51050467
140membrane depolarization during action potential (GO:0086010)2.50961646
141positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.50492696
142regulation of respiratory system process (GO:0044065)2.49254047
143neurotransmitter transport (GO:0006836)2.49118046
144regulation of female receptivity (GO:0045924)2.48683387
145proteasome assembly (GO:0043248)2.48336224
146ferric iron transport (GO:0015682)2.47981018
147trivalent inorganic cation transport (GO:0072512)2.47981018
148neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.47778635
149negative regulation of dendrite development (GO:2000171)2.47242181
150dopamine transport (GO:0015872)2.46659832
151dermatan sulfate biosynthetic process (GO:0030208)2.46618303
152mitochondrion morphogenesis (GO:0070584)2.46585594
153regulation of vesicle fusion (GO:0031338)2.45726554
154cellular ketone body metabolic process (GO:0046950)2.45580425
155platelet dense granule organization (GO:0060155)2.45557511
156peptidyl-tyrosine autophosphorylation (GO:0038083)2.45224414
157negative regulation of calcium ion transmembrane transport (GO:1903170)2.44755054
158negative regulation of calcium ion transmembrane transporter activity (GO:1901020)2.44755054
159cytochrome complex assembly (GO:0017004)2.44596617
160serotonin metabolic process (GO:0042428)2.44586947
161membrane assembly (GO:0071709)2.44089729
162reciprocal DNA recombination (GO:0035825)2.44046696
163reciprocal meiotic recombination (GO:0007131)2.44046696
164nonmotile primary cilium assembly (GO:0035058)2.43654333
165phasic smooth muscle contraction (GO:0014821)2.43583053
166regulation of membrane repolarization (GO:0060306)2.43537091
167regulation of excitatory postsynaptic membrane potential (GO:0060079)2.43330323
168positive regulation of synapse assembly (GO:0051965)2.42346233
169somite development (GO:0061053)2.41270862
170gonadal mesoderm development (GO:0007506)2.39776835
171left/right axis specification (GO:0070986)2.39585389
172L-fucose catabolic process (GO:0042355)2.38756088
173fucose catabolic process (GO:0019317)2.38756088
174L-fucose metabolic process (GO:0042354)2.38756088
175ER overload response (GO:0006983)2.38606273
176regulation of action potential (GO:0098900)2.37897826
177sequestering of extracellular ligand from receptor (GO:0035581)2.37648457
178calcium ion-dependent exocytosis (GO:0017156)2.37550541
179regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.37091544
180inner ear receptor stereocilium organization (GO:0060122)2.37019808
181cranial nerve structural organization (GO:0021604)2.36595056
182regulation of voltage-gated calcium channel activity (GO:1901385)2.36285765
183cell communication by electrical coupling (GO:0010644)2.36081866
184regulation of postsynaptic membrane potential (GO:0060078)2.35598146
185apical protein localization (GO:0045176)2.35523372
186behavioral response to ethanol (GO:0048149)2.35399112
187regulation of acyl-CoA biosynthetic process (GO:0050812)2.34969706
188positive regulation of mitochondrial fission (GO:0090141)2.32747332
189G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.32325148
190smoothened signaling pathway (GO:0007224)2.32172808
191preassembly of GPI anchor in ER membrane (GO:0016254)2.31336723
192quinone biosynthetic process (GO:1901663)2.30760772
193detection of mechanical stimulus involved in sensory perception (GO:0050974)2.28323502
194polyamine metabolic process (GO:0006595)2.28258999

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.73538963
2GBX2_23144817_ChIP-Seq_PC3_Human4.11773333
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.73819749
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.67452873
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.37571667
6GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.34125957
7E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.31518694
8EED_16625203_ChIP-ChIP_MESCs_Mouse2.30551793
9RBPJ_22232070_ChIP-Seq_NCS_Mouse2.28294187
10SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.26023840
11RNF2_18974828_ChIP-Seq_MESCs_Mouse2.25668610
12EZH2_18974828_ChIP-Seq_MESCs_Mouse2.25668610
13SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.25665818
14SALL1_21062744_ChIP-ChIP_HESCs_Human2.24197799
15EZH2_27304074_Chip-Seq_ESCs_Mouse2.22405812
16POU3F2_20337985_ChIP-ChIP_501MEL_Human2.15803981
17SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.15093617
18ZFP57_27257070_Chip-Seq_ESCs_Mouse2.12167216
19JARID2_20075857_ChIP-Seq_MESCs_Mouse2.11178353
20TAF15_26573619_Chip-Seq_HEK293_Human2.07848005
21CTBP2_25329375_ChIP-Seq_LNCAP_Human2.01823294
22AR_21572438_ChIP-Seq_LNCaP_Human2.01179555
23HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.98122131
24MTF2_20144788_ChIP-Seq_MESCs_Mouse1.93652942
25SMAD4_21799915_ChIP-Seq_A2780_Human1.89780438
26FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.87382935
27P300_19829295_ChIP-Seq_ESCs_Human1.87349178
28FUS_26573619_Chip-Seq_HEK293_Human1.85402325
29MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.82832526
30REST_21632747_ChIP-Seq_MESCs_Mouse1.82401907
31RNF2_27304074_Chip-Seq_ESCs_Mouse1.81421376
32SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.79469196
33CTBP1_25329375_ChIP-Seq_LNCAP_Human1.78009686
34OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.76952655
35SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.69988416
36NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.69605733
37EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.67965313
38RARB_27405468_Chip-Seq_BRAIN_Mouse1.66174222
39GATA1_22025678_ChIP-Seq_K562_Human1.65698975
40PIAS1_25552417_ChIP-Seq_VCAP_Human1.65462074
41VDR_22108803_ChIP-Seq_LS180_Human1.65375633
42ZNF274_21170338_ChIP-Seq_K562_Hela1.63619868
43EZH2_27294783_Chip-Seq_ESCs_Mouse1.60541250
44PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.60212845
45REST_18959480_ChIP-ChIP_MESCs_Mouse1.59891750
46HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.59245024
47CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.56811477
48TOP2B_26459242_ChIP-Seq_MCF-7_Human1.56669280
49PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.55562929
50SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.53128518
51ER_23166858_ChIP-Seq_MCF-7_Human1.50167052
52NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.48113633
53SMAD3_21741376_ChIP-Seq_EPCs_Human1.46629246
54GABP_17652178_ChIP-ChIP_JURKAT_Human1.45458557
55TP53_22573176_ChIP-Seq_HFKS_Human1.44104372
56SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.42848526
57DROSHA_22980978_ChIP-Seq_HELA_Human1.42242357
58SOX2_21211035_ChIP-Seq_LN229_Gbm1.40171296
59SUZ12_27294783_Chip-Seq_ESCs_Mouse1.38499113
60EWS_26573619_Chip-Seq_HEK293_Human1.38149045
61NR3C1_23031785_ChIP-Seq_PC12_Mouse1.38059537
62BMI1_23680149_ChIP-Seq_NPCS_Mouse1.38049565
63WT1_19549856_ChIP-ChIP_CCG9911_Human1.37324371
64SMAD4_21741376_ChIP-Seq_EPCs_Human1.36496759
65AR_25329375_ChIP-Seq_VCAP_Human1.35169810
66RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.34505859
67MYC_18940864_ChIP-ChIP_HL60_Human1.33562826
68PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.31243578
69STAT3_23295773_ChIP-Seq_U87_Human1.30357813
70NOTCH1_21737748_ChIP-Seq_TLL_Human1.29458383
71CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.29145853
72EP300_21415370_ChIP-Seq_HL-1_Mouse1.28527433
73TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.28111945
74TP53_18474530_ChIP-ChIP_U2OS_Human1.27956037
75TCF4_23295773_ChIP-Seq_U87_Human1.26900888
76KLF5_20875108_ChIP-Seq_MESCs_Mouse1.26050395
77KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.25855302
78SMAD_19615063_ChIP-ChIP_OVARY_Human1.25083835
79AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.25080664
80GATA3_21878914_ChIP-Seq_MCF-7_Human1.24881959
81CBX2_27304074_Chip-Seq_ESCs_Mouse1.23485784
82TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.23144170
83POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.23144170
84RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.22105581
85TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.19990882
86TCF4_22108803_ChIP-Seq_LS180_Human1.19245809
87CBP_20019798_ChIP-Seq_JUKART_Human1.18420739
88IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.18420739
89FOXA1_27270436_Chip-Seq_PROSTATE_Human1.18159593
90FOXA1_25329375_ChIP-Seq_VCAP_Human1.18159593
91IGF1R_20145208_ChIP-Seq_DFB_Human1.17385761
92NANOG_19829295_ChIP-Seq_ESCs_Human1.16950096
93SOX2_19829295_ChIP-Seq_ESCs_Human1.16950096
94FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.16176502
95EST1_17652178_ChIP-ChIP_JURKAT_Human1.15751557
96ZNF217_24962896_ChIP-Seq_MCF-7_Human1.15054451
97UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.14246917
98YAP1_20516196_ChIP-Seq_MESCs_Mouse1.13812094
99TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.13059329
100RNF2_27304074_Chip-Seq_NSC_Mouse1.12759763
101NR3C1_21868756_ChIP-Seq_MCF10A_Human1.11543241
102HOXB7_26014856_ChIP-Seq_BT474_Human1.10967230
103RUNX2_22187159_ChIP-Seq_PCA_Human1.10600205
104MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.10412812
105EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.09793516
106CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.08477962
107ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.08102621
108NCOR_22424771_ChIP-Seq_293T_Human1.06504051
109NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.06484388
110NRF2_20460467_ChIP-Seq_MEFs_Mouse1.06484388
111AR_19668381_ChIP-Seq_PC3_Human1.06318410
112CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06155665
113JUN_21703547_ChIP-Seq_K562_Human1.05561675
114NANOG_18555785_Chip-Seq_ESCs_Mouse1.04737974
115GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04473304
116GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.04241820
117ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.02757700
118E2F1_18555785_Chip-Seq_ESCs_Mouse1.02646935
119PCGF2_27294783_Chip-Seq_ESCs_Mouse1.02491139
120MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.01364395
121SOX9_26525672_Chip-Seq_HEART_Mouse1.01323182
122FLI1_21867929_ChIP-Seq_TH2_Mouse1.00594414
123ARNT_22903824_ChIP-Seq_MCF-7_Human1.00249783
124PRDM14_20953172_ChIP-Seq_ESCs_Human1.00184956
125P53_22387025_ChIP-Seq_ESCs_Mouse0.99883080
126SOX9_26525672_Chip-Seq_Limbbuds_Mouse0.97803025
127FLI1_27457419_Chip-Seq_LIVER_Mouse0.97639613
128BCAT_22108803_ChIP-Seq_LS180_Human0.97585847
129TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.96692945
130ERA_21632823_ChIP-Seq_H3396_Human0.96673639
131EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.95971725
132ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.94605113
133SMAD4_21741376_ChIP-Seq_HESCs_Human0.93990858
134CDX2_19796622_ChIP-Seq_MESCs_Mouse0.93905611
135KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.93714112
136* AR_20517297_ChIP-Seq_VCAP_Human0.93443123
137JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.91518164
138FOXA1_21572438_ChIP-Seq_LNCaP_Human0.91079431
139MYC_19829295_ChIP-Seq_ESCs_Human0.90071658

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity3.57006861
2MP0003880_abnormal_central_pattern3.02347789
3MP0005503_abnormal_tendon_morphology2.87723489
4MP0003635_abnormal_synaptic_transmissio2.53240604
5MP0002837_dystrophic_cardiac_calcinosis2.52520675
6MP0004270_analgesia2.47944540
7MP0003195_calcinosis2.45822803
8MP0009780_abnormal_chondrocyte_physiolo2.35556888
9MP0000751_myopathy2.25618225
10MP0008872_abnormal_physiological_respon2.24211767
11MP0002638_abnormal_pupillary_reflex2.23255533
12MP0008438_abnormal_cutaneous_collagen2.19849464
13MP0003122_maternal_imprinting2.19391039
14MP0002734_abnormal_mechanical_nocicepti2.15127322
15MP0001968_abnormal_touch/_nociception2.14008226
16MP0004145_abnormal_muscle_electrophysio2.13724369
17MP0008875_abnormal_xenobiotic_pharmacok2.10086278
18MP0002102_abnormal_ear_morphology2.09468996
19MP0008877_abnormal_DNA_methylation2.07226719
20MP0009046_muscle_twitch2.03694434
21MP0001984_abnormal_olfaction2.02583758
22MP0009745_abnormal_behavioral_response1.99545240
23MP0002063_abnormal_learning/memory/cond1.99484130
24MP0010386_abnormal_urinary_bladder1.97842502
25MP0002064_seizures1.94374248
26MP0003136_yellow_coat_color1.91992596
27MP0005423_abnormal_somatic_nervous1.90815946
28MP0000749_muscle_degeneration1.90434534
29MP0002735_abnormal_chemical_nociception1.89492430
30MP0002272_abnormal_nervous_system1.89027076
31MP0002653_abnormal_ependyma_morphology1.86322877
32MP0005451_abnormal_body_composition1.85567276
33MP0002736_abnormal_nociception_after1.82909729
34MP0002572_abnormal_emotion/affect_behav1.78502970
35MP0005275_abnormal_skin_tensile1.67937754
36MP0004215_abnormal_myocardial_fiber1.64724702
37MP0004142_abnormal_muscle_tone1.64449896
38MP0000569_abnormal_digit_pigmentation1.61003268
39MP0005646_abnormal_pituitary_gland1.59613842
40MP0000013_abnormal_adipose_tissue1.50464189
41MP0006292_abnormal_olfactory_placode1.45424400
42MP0004133_heterotaxia1.42434574
43MP0001299_abnormal_eye_distance/1.42349954
44MP0001486_abnormal_startle_reflex1.42068219
45MP0005499_abnormal_olfactory_system1.41270615
46MP0005394_taste/olfaction_phenotype1.41270615
47MP0008789_abnormal_olfactory_epithelium1.40458874
48MP0002067_abnormal_sensory_capabilities1.40434467
49MP0002108_abnormal_muscle_morphology1.40054066
50MP0002938_white_spotting1.39591587
51MP0005171_absent_coat_pigmentation1.37391901
52MP0002184_abnormal_innervation1.36384478
53MP0006276_abnormal_autonomic_nervous1.34879796
54MP0004885_abnormal_endolymph1.34434115
55MP0003890_abnormal_embryonic-extraembry1.33291505
56MP0006072_abnormal_retinal_apoptosis1.30901175
57MP0004233_abnormal_muscle_weight1.30574373
58MP0001970_abnormal_pain_threshold1.30385039
59MP0001188_hyperpigmentation1.29546451
60MP0000778_abnormal_nervous_system1.27153380
61MP0004147_increased_porphyrin_level1.27021528
62MP0000566_synostosis1.26844472
63MP0003718_maternal_effect1.25572714
64MP0005623_abnormal_meninges_morphology1.23791668
65MP0001501_abnormal_sleep_pattern1.22994434
66MP0004036_abnormal_muscle_relaxation1.22615959
67MP0000427_abnormal_hair_cycle1.21003750
68MP0002557_abnormal_social/conspecific_i1.20553108
69MP0000049_abnormal_middle_ear1.20315773
70MP0005645_abnormal_hypothalamus_physiol1.20119844
71MP0001485_abnormal_pinna_reflex1.19080073
72MP0004811_abnormal_neuron_physiology1.16970482
73MP0004858_abnormal_nervous_system1.15237873
74MP0003119_abnormal_digestive_system1.14560806
75MP0004924_abnormal_behavior1.13096305
76MP0005386_behavior/neurological_phenoty1.13096305
77MP0002733_abnormal_thermal_nociception1.12917585
78MP0005551_abnormal_eye_electrophysiolog1.12782735
79MP0005084_abnormal_gallbladder_morpholo1.12179857
80MP0002822_catalepsy1.11788767
81MP0005620_abnormal_muscle_contractility1.10989954
82MP0000955_abnormal_spinal_cord1.09762520
83MP0001440_abnormal_grooming_behavior1.09620809
84MP0001177_atelectasis1.08795324
85MP0002882_abnormal_neuron_morphology1.08337814
86MP0005174_abnormal_tail_pigmentation1.08303317
87MP0008569_lethality_at_weaning1.08007327
88MP0003123_paternal_imprinting1.06871179
89MP0001529_abnormal_vocalization1.06329853
90MP0000026_abnormal_inner_ear1.04543490
91MP0002909_abnormal_adrenal_gland1.03923837
92MP0004084_abnormal_cardiac_muscle1.02510709
93MP0009250_abnormal_appendicular_skeleto1.01270833
94MP0002160_abnormal_reproductive_system1.01169515
95MP0005195_abnormal_posterior_eye0.99975296
96MP0001502_abnormal_circadian_rhythm0.99674484
97MP0004742_abnormal_vestibular_system0.99629491
98MP0004484_altered_response_of0.99313775
99MP0002752_abnormal_somatic_nervous0.99093944
100MP0008775_abnormal_heart_ventricle0.99068011
101MP0003121_genomic_imprinting0.98811349
102MP0008058_abnormal_DNA_repair0.97785187
103MP0003787_abnormal_imprinting0.95629773
104MP0005369_muscle_phenotype0.95066012
105MP0001986_abnormal_taste_sensitivity0.93986932
106MP0004085_abnormal_heartbeat0.92593680
107MP0000383_abnormal_hair_follicle0.92558814
108MP0000538_abnormal_urinary_bladder0.91891376
109MP0004043_abnormal_pH_regulation0.91277836
110MP0003283_abnormal_digestive_organ0.90539141
111MP0002066_abnormal_motor_capabilities/c0.90123910
112MP0003698_abnormal_male_reproductive0.89428622
113MP0003942_abnormal_urinary_system0.89098068
114MP0000631_abnormal_neuroendocrine_gland0.88754392
115MP0001905_abnormal_dopamine_level0.88222005
116MP0003137_abnormal_impulse_conducting0.87801449
117MP0003938_abnormal_ear_development0.87494914
118MP0000534_abnormal_ureter_morphology0.87402931
119MP0001963_abnormal_hearing_physiology0.87395333
120MP0001756_abnormal_urination0.86492273
121MP0000230_abnormal_systemic_arterial0.86037967
122MP0003879_abnormal_hair_cell0.84828325
123MP0002751_abnormal_autonomic_nervous0.84756382
124MP0002972_abnormal_cardiac_muscle0.84581208
125MP0000759_abnormal_skeletal_muscle0.84521917
126MP0000537_abnormal_urethra_morphology0.83363913
127MP0000747_muscle_weakness0.83216850
128MP0003941_abnormal_skin_development0.82892245
129MP0005253_abnormal_eye_physiology0.82183110
130MP0005508_abnormal_skeleton_morphology0.82174095
131MP0003385_abnormal_body_wall0.81509410
132MP0003937_abnormal_limbs/digits/tail_de0.81356912
133MP0004130_abnormal_muscle_cell0.80676365
134MP0002269_muscular_atrophy0.79638248
135MP0003646_muscle_fatigue0.79085265
136MP0002229_neurodegeneration0.78674944
137MP0005167_abnormal_blood-brain_barrier0.77861443
138MP0002152_abnormal_brain_morphology0.77783270
139MP0005367_renal/urinary_system_phenotyp0.77695568
140MP0000516_abnormal_urinary_system0.77695568
141MP0002896_abnormal_bone_mineralization0.77611403
142MP0002234_abnormal_pharynx_morphology0.75772276
143MP0002106_abnormal_muscle_physiology0.74752829

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)5.02603760
2Pancreatic cysts (HP:0001737)4.17726201
3True hermaphroditism (HP:0010459)4.06940927
4Abnormality of midbrain morphology (HP:0002418)4.00559478
5Molar tooth sign on MRI (HP:0002419)4.00559478
6Atonic seizures (HP:0010819)3.85244710
7Type II lissencephaly (HP:0007260)3.60856059
8Birth length less than 3rd percentile (HP:0003561)3.58430155
9Febrile seizures (HP:0002373)3.50183427
10Epileptic encephalopathy (HP:0200134)3.48172957
11Nephronophthisis (HP:0000090)3.34766458
12Focal seizures (HP:0007359)3.26045104
13Pheochromocytoma (HP:0002666)3.19124248
14Cerebellar dysplasia (HP:0007033)3.01332870
15Progressive cerebellar ataxia (HP:0002073)2.96016102
16Dynein arm defect of respiratory motile cilia (HP:0012255)2.95963121
17Absent/shortened dynein arms (HP:0200106)2.95963121
18Myokymia (HP:0002411)2.93081717
19Absence seizures (HP:0002121)2.92356557
20Cystic liver disease (HP:0006706)2.85966665
21Large for gestational age (HP:0001520)2.85068972
22Neuroendocrine neoplasm (HP:0100634)2.83641436
23Visual hallucinations (HP:0002367)2.79746312
24Abnormal respiratory epithelium morphology (HP:0012253)2.78860129
25Abnormal respiratory motile cilium morphology (HP:0005938)2.78860129
26Abnormality of the renal medulla (HP:0100957)2.78246454
27Abnormal hair whorl (HP:0010721)2.72360045
28Inability to walk (HP:0002540)2.66456275
29Attenuation of retinal blood vessels (HP:0007843)2.61218333
30Patellar aplasia (HP:0006443)2.60991544
31Dialeptic seizures (HP:0011146)2.59569118
32Genetic anticipation (HP:0003743)2.59297997
33Sclerocornea (HP:0000647)2.59183368
34Aplasia/Hypoplasia of the tongue (HP:0010295)2.58471688
35Abnormal ciliary motility (HP:0012262)2.56228656
36Pendular nystagmus (HP:0012043)2.55664778
37Absent speech (HP:0001344)2.52104775
38Scanning speech (HP:0002168)2.52015459
39Abnormal respiratory motile cilium physiology (HP:0012261)2.50379705
40Broad distal phalanx of finger (HP:0009836)2.49778739
41Generalized tonic-clonic seizures (HP:0002069)2.46484473
42Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.43429854
43Aplasia/Hypoplasia of the patella (HP:0006498)2.43150701
44Congenital primary aphakia (HP:0007707)2.41290012
45Gait imbalance (HP:0002141)2.39618154
46Hypothermia (HP:0002045)2.39418364
4711 pairs of ribs (HP:0000878)2.39186862
48Postaxial foot polydactyly (HP:0001830)2.37899796
49Aplasia/Hypoplasia of the tibia (HP:0005772)2.36212709
50Hyperventilation (HP:0002883)2.34863482
51Action tremor (HP:0002345)2.34205270
52Lissencephaly (HP:0001339)2.33866366
53Truncal ataxia (HP:0002078)2.32472592
54Abolished electroretinogram (ERG) (HP:0000550)2.32204581
55Prolonged QT interval (HP:0001657)2.30406798
56Retinal dysplasia (HP:0007973)2.29823117
57Poor eye contact (HP:0000817)2.29703477
58Male pseudohermaphroditism (HP:0000037)2.29533132
59Furrowed tongue (HP:0000221)2.29044285
60Gaze-evoked nystagmus (HP:0000640)2.28276211
61Chronic hepatic failure (HP:0100626)2.26535755
62Anencephaly (HP:0002323)2.26162431
63Neoplasm of the peripheral nervous system (HP:0100007)2.24838155
64Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.23748559
65Abnormality of alanine metabolism (HP:0010916)2.23748559
66Hyperalaninemia (HP:0003348)2.23748559
67Protruding tongue (HP:0010808)2.21654321
68Keratoconus (HP:0000563)2.21325982
69Increased corneal curvature (HP:0100692)2.21325982
70Chorioretinal atrophy (HP:0000533)2.21093421
71Myotonia (HP:0002486)2.20504163
72Insulin-resistant diabetes mellitus (HP:0000831)2.20412848
73Calf muscle hypertrophy (HP:0008981)2.18307842
74Depression (HP:0000716)2.16565981
75Central scotoma (HP:0000603)2.16385077
76Abnormality of the calf musculature (HP:0001430)2.15906822
77Medial flaring of the eyebrow (HP:0010747)2.15228453
78Severe muscular hypotonia (HP:0006829)2.13697473
79Hypoventilation (HP:0002791)2.12955236
80Delayed gross motor development (HP:0002194)2.12896536
81Hyperinsulinemic hypoglycemia (HP:0000825)2.10355708
82Abnormality of the renal cortex (HP:0011035)2.10200581
83Congenital hepatic fibrosis (HP:0002612)2.09000426
84Oligodactyly (hands) (HP:0001180)2.07137481
85Nephrogenic diabetes insipidus (HP:0009806)2.06791580
86Progressive inability to walk (HP:0002505)2.06455268
87Muscle hypertrophy of the lower extremities (HP:0008968)2.06377309
88Bradycardia (HP:0001662)2.06374423
89Pancreatic islet-cell hyperplasia (HP:0004510)2.05996657
90Microretrognathia (HP:0000308)2.04716278
91Genital tract atresia (HP:0001827)2.04303443
92Dysmetric saccades (HP:0000641)2.03638387
93Long foot (HP:0001833)2.01137114
94Rhinitis (HP:0012384)1.99731715
95Dysdiadochokinesis (HP:0002075)1.97574089
96Anxiety (HP:0000739)1.96755965
97Irregular vertebral endplates (HP:0003301)1.96674860
98Preaxial hand polydactyly (HP:0001177)1.95525894
99Vaginal atresia (HP:0000148)1.95504008
100Epileptiform EEG discharges (HP:0011182)1.95155929
101Decreased central vision (HP:0007663)1.94829916
102Sudden death (HP:0001699)1.94714212
103Acute necrotizing encephalopathy (HP:0006965)1.94177248
104Microglossia (HP:0000171)1.93996509
105Impaired smooth pursuit (HP:0007772)1.93070686
106Fair hair (HP:0002286)1.92616698
107Exercise-induced myalgia (HP:0003738)1.92609789
108Congenital, generalized hypertrichosis (HP:0004540)1.91195272
109Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.90900268
110Postaxial hand polydactyly (HP:0001162)1.88072753
111Abnormal EKG (HP:0003115)1.87643892
112Progressive macrocephaly (HP:0004481)1.87613652
113Radial bowing (HP:0002986)1.87398592
114Tubular atrophy (HP:0000092)1.86853829
115Poor coordination (HP:0002370)1.86111234
116Protrusio acetabuli (HP:0003179)1.86103449
117Broad-based gait (HP:0002136)1.85935691
118Overgrowth (HP:0001548)1.85695190
119Clumsiness (HP:0002312)1.85431471
120Congenital stationary night blindness (HP:0007642)1.85353812
121Scrotal hypoplasia (HP:0000046)1.85303640
122Spinal cord compression (HP:0002176)1.85128521
123EEG with generalized epileptiform discharges (HP:0011198)1.85119716
124Labial hypoplasia (HP:0000066)1.82995844
125Fetal akinesia sequence (HP:0001989)1.82887049
126Abnormal mitochondria in muscle tissue (HP:0008316)1.82332204
127Unsteady gait (HP:0002317)1.80952801
128Abnormal rod and cone electroretinograms (HP:0008323)1.79995832
129Decreased electroretinogram (ERG) amplitude (HP:0000654)1.79825013
130Exercise-induced muscle cramps (HP:0003710)1.79570362
131Hepatocellular necrosis (HP:0001404)1.78769196
132Hypsarrhythmia (HP:0002521)1.78287109
133Primary atrial arrhythmia (HP:0001692)1.77920570
134Occipital encephalocele (HP:0002085)1.77877796
135Acute encephalopathy (HP:0006846)1.77134047
136Premature rupture of membranes (HP:0001788)1.76852364
137Resting tremor (HP:0002322)1.76842004
138Short tibia (HP:0005736)1.76018586
139Abnormal social behavior (HP:0012433)1.75384946
140Impaired social interactions (HP:0000735)1.75384946
141Mild short stature (HP:0003502)1.75355586
142Bony spicule pigmentary retinopathy (HP:0007737)1.74647174
143Abnormality of the labia minora (HP:0012880)1.74588473
144Aganglionic megacolon (HP:0002251)1.74272881
145Drooling (HP:0002307)1.73853220
146Atrial fibrillation (HP:0005110)1.73327722
147Hypoglycemic seizures (HP:0002173)1.73123747
148Aplasia/Hypoplasia involving the musculature (HP:0001460)1.72931148
149Hyperglycemia (HP:0003074)1.70369039
150Failure to thrive in infancy (HP:0001531)1.70293189
151Neoplasm of the adrenal gland (HP:0100631)1.69287933
152Hepatic necrosis (HP:0002605)1.68518017
153Hemiparesis (HP:0001269)1.68435817
154Dyskinesia (HP:0100660)1.68108987
155Supraventricular tachycardia (HP:0004755)1.67812578
156Breast hypoplasia (HP:0003187)1.66789202
157Ankle clonus (HP:0011448)1.66730654
158Oculomotor apraxia (HP:0000657)1.66675967
159Impaired vibration sensation in the lower limbs (HP:0002166)1.66286999
160Scotoma (HP:0000575)1.64659630
161Flared iliac wings (HP:0002869)1.64028847
162Type 1 muscle fiber predominance (HP:0003803)1.62656193
163Shoulder girdle muscle weakness (HP:0003547)1.61897799
164Supraventricular arrhythmia (HP:0005115)1.61449650
165Mitochondrial inheritance (HP:0001427)1.60016829
166Pancreatic fibrosis (HP:0100732)1.59219349
167Abnormality of pain sensation (HP:0010832)1.59191762
168Impaired pain sensation (HP:0007328)1.59191762
169Hypoplastic female external genitalia (HP:0012815)1.58867421
170Neonatal short-limb short stature (HP:0008921)1.58838008
171Abnormality of ocular smooth pursuit (HP:0000617)1.58599600
172Left ventricular hypertrophy (HP:0001712)1.58351131
173Aplasia/Hypoplasia of the lens (HP:0008063)1.57818625
174Increased CSF lactate (HP:0002490)1.57672773

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BMPR1B4.26084178
2INSRR4.00757202
3NTRK33.64561132
4CASK3.53412581
5ADRBK23.26276072
6MAP2K73.00004697
7EPHA42.70663486
8MAP3K42.42808369
9PLK22.30261499
10NUAK12.25335936
11MAP3K122.19692983
12GRK12.12773931
13ERBB32.11888414
14MINK12.02369363
15TLK12.01421273
16MAP4K22.01275140
17CAMKK21.92252028
18SIK21.91273996
19CCNB11.85947135
20MAP2K41.79667538
21TGFBR11.75456572
22AKT31.74802788
23NTRK11.72186368
24WNK31.70828973
25ZAK1.64117412
26MARK11.62167810
27TNIK1.59532353
28PRPF4B1.59467907
29SGK21.54700046
30CDK191.53179760
31LATS11.51452386
32WNK41.51133402
33FER1.50263145
34OBSCN1.46355605
35MAPK151.45347753
36SGK4941.40042790
37SGK2231.40042790
38PINK11.39687337
39MKNK21.36458010
40PDGFRA1.35571371
41PRKD31.34906027
42MAPK131.32875593
43FRK1.27035453
44CAMKK11.26815862
45ACVR1B1.26105664
46PHKG11.22674837
47PHKG21.22674837
48BRSK21.20823984
49MAP3K91.19202367
50NEK21.17548482
51TRIM281.17075703
52DAPK21.12612434
53ARAF1.12131313
54NME11.10793277
55BCR1.08263493
56PDK31.06113418
57PDK41.06113418
58MAP3K21.04559661
59CSNK1G11.01867283
60PBK1.00369074
61LIMK10.99333132
62BMPR20.97527637
63CSNK1G30.95949777
64CAMK2A0.95816016
65SIK30.95070102
66CAMK2B0.92152725
67CDK50.92034816
68VRK10.91784759
69TIE10.91707070
70SGK30.89634495
71GRK50.88286338
72KSR10.88212261
73TSSK60.87818660
74EIF2AK10.87389852
75CSNK1A1L0.87129972
76PASK0.86774220
77DAPK10.86185720
78PRKCE0.84352678
79TAOK30.83828668
80CAMK2D0.82904302
81TRPM70.81910007
82OXSR10.81751135
83SCYL20.79829786
84UHMK10.78791572
85MYLK0.78551970
86FGFR20.78436700
87NEK10.78329764
88PIK3CA0.78109414
89BCKDK0.78108766
90DYRK20.77534705
91STK390.77502938
92PRKCG0.76413634
93RET0.75600550
94WNK10.74323888
95PAK60.70321517
96CAMK40.67287307
97WEE10.66484769
98PKN10.66233808
99RPS6KA50.64199736
100DYRK1A0.63982229
101PDK20.61517005
102EIF2AK30.61059967
103STK38L0.60944799
104BRAF0.60890779
105PLK30.60873501
106EPHB20.60610999
107MUSK0.60529057
108NTRK20.59963921
109STK30.59289147
110STK160.58699899
111MET0.58275081
112CDK140.58157126
113PLK40.57668667
114MKNK10.55667307
115MAP2K10.54157632
116ADRBK10.52692384
117ERBB40.52665970
118CAMK2G0.51890188
119PLK10.51806588
120CDK180.51226893
121RAF10.50968365
122PRKAA10.50956367
123PRKCH0.50544525
124CSNK1G20.49484198
125PAK30.49373542
126PNCK0.49344989
127CDK80.48278821
128VRK20.47045257
129FGFR10.46886245
130LMTK20.46137894
131CAMK10.44809355
132NEK60.43646453
133CSNK1A10.41811802
134MAP3K50.40812505
135PTK2B0.40757401
136DDR20.40400908
137CDK150.40303380
138LATS20.39811530
139MAPK100.39751394
140CSNK1D0.39487577
141CHEK20.39092858
142SGK10.38646471
143BRSK10.38606503
144MELK0.38353729
145PRKAA20.38229211
146FLT30.37806015
147RPS6KB10.35717714
148PDGFRB0.35166361
149MAP2K60.34957737
150PRKACA0.34311936
151CDC42BPA0.34288103
152CDC70.32176563

Predicted pathways (KEGG)

RankGene SetZ-score
1Synaptic vesicle cycle_Homo sapiens_hsa047213.31167154
2Selenocompound metabolism_Homo sapiens_hsa004503.02435232
3Nicotine addiction_Homo sapiens_hsa050332.68295527
4Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.36208819
5GABAergic synapse_Homo sapiens_hsa047272.32958361
6Olfactory transduction_Homo sapiens_hsa047402.30019385
7Circadian entrainment_Homo sapiens_hsa047132.27275555
8Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.26389500
9Amphetamine addiction_Homo sapiens_hsa050312.26364984
10Insulin secretion_Homo sapiens_hsa049112.25597365
11Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006042.23501783
12Butanoate metabolism_Homo sapiens_hsa006502.17051453
13Collecting duct acid secretion_Homo sapiens_hsa049662.14518574
14Long-term potentiation_Homo sapiens_hsa047202.13568221
15Morphine addiction_Homo sapiens_hsa050322.08979668
16Nitrogen metabolism_Homo sapiens_hsa009102.04621709
17Vibrio cholerae infection_Homo sapiens_hsa051102.04453101
18Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.03898073
19Protein export_Homo sapiens_hsa030602.02840092
20Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.00297998
21Dopaminergic synapse_Homo sapiens_hsa047281.97144074
22Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.81236449
23Glutamatergic synapse_Homo sapiens_hsa047241.80348545
24Phototransduction_Homo sapiens_hsa047441.78490335
25Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.76023874
26Taste transduction_Homo sapiens_hsa047421.73586142
27Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.67805918
28Cholinergic synapse_Homo sapiens_hsa047251.66140062
29Serotonergic synapse_Homo sapiens_hsa047261.61875048
30Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.57838122
31Homologous recombination_Homo sapiens_hsa034401.56738718
32Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.56155496
33Linoleic acid metabolism_Homo sapiens_hsa005911.54028874
34Oxidative phosphorylation_Homo sapiens_hsa001901.49872538
35Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.49181996
36Cocaine addiction_Homo sapiens_hsa050301.48935033
37Tryptophan metabolism_Homo sapiens_hsa003801.46932940
38Basal transcription factors_Homo sapiens_hsa030221.46765978
39Dilated cardiomyopathy_Homo sapiens_hsa054141.44256974
40Cardiac muscle contraction_Homo sapiens_hsa042601.41027191
41Peroxisome_Homo sapiens_hsa041461.39578828
42Ether lipid metabolism_Homo sapiens_hsa005651.39374110
43RNA polymerase_Homo sapiens_hsa030201.36762305
44ABC transporters_Homo sapiens_hsa020101.33856915
45Fanconi anemia pathway_Homo sapiens_hsa034601.32927966
46alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.32676608
47Parkinsons disease_Homo sapiens_hsa050121.30808980
48Caffeine metabolism_Homo sapiens_hsa002321.29918207
49Aldosterone synthesis and secretion_Homo sapiens_hsa049251.28970004
50Sulfur relay system_Homo sapiens_hsa041221.28910694
51Calcium signaling pathway_Homo sapiens_hsa040201.27564422
52Renin secretion_Homo sapiens_hsa049241.24020678
53Oxytocin signaling pathway_Homo sapiens_hsa049211.23937210
54Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.23911204
55Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.22681012
56Propanoate metabolism_Homo sapiens_hsa006401.21701957
57Long-term depression_Homo sapiens_hsa047301.21393622
58SNARE interactions in vesicular transport_Homo sapiens_hsa041301.20730275
59Chemical carcinogenesis_Homo sapiens_hsa052041.18545629
60Gastric acid secretion_Homo sapiens_hsa049711.17541422
61Type II diabetes mellitus_Homo sapiens_hsa049301.17008815
62Salivary secretion_Homo sapiens_hsa049701.16684252
63Alzheimers disease_Homo sapiens_hsa050101.15674010
64beta-Alanine metabolism_Homo sapiens_hsa004101.12070437
65Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.11099402
66Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.11059258
67Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.10212265
68cGMP-PKG signaling pathway_Homo sapiens_hsa040221.05228107
69Glioma_Homo sapiens_hsa052141.03177528
70Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.01931442
71GnRH signaling pathway_Homo sapiens_hsa049120.99365958
72Fatty acid elongation_Homo sapiens_hsa000620.98824086
73Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.98581513
74cAMP signaling pathway_Homo sapiens_hsa040240.97439133
75Gap junction_Homo sapiens_hsa045400.96121911
76RNA degradation_Homo sapiens_hsa030180.95716272
77Melanogenesis_Homo sapiens_hsa049160.94919072
78Oocyte meiosis_Homo sapiens_hsa041140.93926282
79Histidine metabolism_Homo sapiens_hsa003400.92474105
80Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.91672856
81Circadian rhythm_Homo sapiens_hsa047100.90271469
82Steroid hormone biosynthesis_Homo sapiens_hsa001400.89280603
83Axon guidance_Homo sapiens_hsa043600.89244918
84Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.88514921
85Pancreatic secretion_Homo sapiens_hsa049720.87443876
86ErbB signaling pathway_Homo sapiens_hsa040120.86632258
87Glucagon signaling pathway_Homo sapiens_hsa049220.85583175
88Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.83660931
89Estrogen signaling pathway_Homo sapiens_hsa049150.81649307
90Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.81391777
91Alcoholism_Homo sapiens_hsa050340.81089734
92Phosphatidylinositol signaling system_Homo sapiens_hsa040700.78809992
93Huntingtons disease_Homo sapiens_hsa050160.78465679
94Cysteine and methionine metabolism_Homo sapiens_hsa002700.78143657
95Thyroid hormone synthesis_Homo sapiens_hsa049180.77828027
96Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.76212227
97Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.75921985
98Primary bile acid biosynthesis_Homo sapiens_hsa001200.74692537
99Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.74668500
100Vascular smooth muscle contraction_Homo sapiens_hsa042700.74532667
101Purine metabolism_Homo sapiens_hsa002300.74398191
102Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.72791957
103Glycerolipid metabolism_Homo sapiens_hsa005610.72327334
104Pyruvate metabolism_Homo sapiens_hsa006200.72045992
105Metabolic pathways_Homo sapiens_hsa011000.71665835
106Nucleotide excision repair_Homo sapiens_hsa034200.70359740
107Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.69838799
108Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.69655405
109Retinol metabolism_Homo sapiens_hsa008300.68722833
110Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.66065789
111Type I diabetes mellitus_Homo sapiens_hsa049400.65221424
112Melanoma_Homo sapiens_hsa052180.65128652
113Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.64786960
114Proteasome_Homo sapiens_hsa030500.64319059
115Steroid biosynthesis_Homo sapiens_hsa001000.64169741
116Arginine and proline metabolism_Homo sapiens_hsa003300.63130572
117Non-homologous end-joining_Homo sapiens_hsa034500.62955886
118Insulin signaling pathway_Homo sapiens_hsa049100.62029578
119Endometrial cancer_Homo sapiens_hsa052130.61989809
120One carbon pool by folate_Homo sapiens_hsa006700.61098317
121Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.59701331
122Ras signaling pathway_Homo sapiens_hsa040140.59310331
123Maturity onset diabetes of the young_Homo sapiens_hsa049500.59209938
124Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.58714655
125Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.56636412
126Fat digestion and absorption_Homo sapiens_hsa049750.56344559
127Wnt signaling pathway_Homo sapiens_hsa043100.55866058
128Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.55360633
129Basal cell carcinoma_Homo sapiens_hsa052170.55336313
130Mismatch repair_Homo sapiens_hsa034300.54133223
131Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.53198013
132Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.52381222
133MAPK signaling pathway_Homo sapiens_hsa040100.52333138
134N-Glycan biosynthesis_Homo sapiens_hsa005100.52158841
135Mineral absorption_Homo sapiens_hsa049780.51515261
136Pyrimidine metabolism_Homo sapiens_hsa002400.50117015
137Longevity regulating pathway - mammal_Homo sapiens_hsa042110.48973520
138Arachidonic acid metabolism_Homo sapiens_hsa005900.47779107
139Sphingolipid metabolism_Homo sapiens_hsa006000.46983034
140Fatty acid degradation_Homo sapiens_hsa000710.46896938
141Regulation of autophagy_Homo sapiens_hsa041400.45842947
142Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.44202247
143Focal adhesion_Homo sapiens_hsa045100.43136357
144Hippo signaling pathway_Homo sapiens_hsa043900.43132983
145Tight junction_Homo sapiens_hsa045300.42408712
146Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.41870984
147Phospholipase D signaling pathway_Homo sapiens_hsa040720.41783891
148Hedgehog signaling pathway_Homo sapiens_hsa043400.41766478
149Renal cell carcinoma_Homo sapiens_hsa052110.39969321
150Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.38939461
151Sulfur metabolism_Homo sapiens_hsa009200.38162978
152TGF-beta signaling pathway_Homo sapiens_hsa043500.37977531
153Thyroid hormone signaling pathway_Homo sapiens_hsa049190.37893044
154Prostate cancer_Homo sapiens_hsa052150.37841576
155Neurotrophin signaling pathway_Homo sapiens_hsa047220.37579592
156Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.36324176
157Ovarian steroidogenesis_Homo sapiens_hsa049130.36289019

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