Rank | Gene Set | Z-score |
---|---|---|
1 | protein localization to kinetochore (GO:0034501) | 5.47358413 |
2 | mitotic metaphase plate congression (GO:0007080) | 5.41505601 |
3 | mitotic chromosome condensation (GO:0007076) | 5.01461439 |
4 | metaphase plate congression (GO:0051310) | 4.82527020 |
5 | attachment of spindle microtubules to kinetochore (GO:0008608) | 4.77175549 |
6 | protein localization to chromosome, centromeric region (GO:0071459) | 4.71610855 |
7 | DNA replication initiation (GO:0006270) | 4.59163389 |
8 | CENP-A containing nucleosome assembly (GO:0034080) | 4.48504272 |
9 | chromatin remodeling at centromere (GO:0031055) | 4.47575282 |
10 | mitotic nuclear envelope disassembly (GO:0007077) | 4.42149601 |
11 | nuclear pore organization (GO:0006999) | 4.37120733 |
12 | kinetochore organization (GO:0051383) | 4.36436854 |
13 | mitotic sister chromatid segregation (GO:0000070) | 4.35784193 |
14 | mitotic sister chromatid cohesion (GO:0007064) | 4.35322152 |
15 | nuclear pore complex assembly (GO:0051292) | 4.32198563 |
16 | establishment of chromosome localization (GO:0051303) | 4.31122417 |
17 | meiotic chromosome segregation (GO:0045132) | 4.27178543 |
18 | DNA unwinding involved in DNA replication (GO:0006268) | 4.17543166 |
19 | DNA replication-independent nucleosome organization (GO:0034724) | 4.15262302 |
20 | DNA replication-independent nucleosome assembly (GO:0006336) | 4.15262302 |
21 | membrane disassembly (GO:0030397) | 4.14038099 |
22 | nuclear envelope disassembly (GO:0051081) | 4.14038099 |
23 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.11772052 |
24 | histone exchange (GO:0043486) | 4.08640792 |
25 | DNA replication checkpoint (GO:0000076) | 4.07679329 |
26 | sister chromatid segregation (GO:0000819) | 3.99768695 |
27 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.99227233 |
28 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.99227233 |
29 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.94657465 |
30 | regulation of spindle organization (GO:0090224) | 3.94187342 |
31 | regulation of DNA endoreduplication (GO:0032875) | 3.93229873 |
32 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.90948710 |
33 | DNA strand elongation (GO:0022616) | 3.90792266 |
34 | kinetochore assembly (GO:0051382) | 3.86627485 |
35 | telomere maintenance via recombination (GO:0000722) | 3.83825850 |
36 | regulation of sister chromatid cohesion (GO:0007063) | 3.80781193 |
37 | protein K6-linked ubiquitination (GO:0085020) | 3.76988099 |
38 | mitotic recombination (GO:0006312) | 3.75095534 |
39 | DNA topological change (GO:0006265) | 3.74108682 |
40 | spindle checkpoint (GO:0031577) | 3.73379491 |
41 | positive regulation of chromosome segregation (GO:0051984) | 3.73295920 |
42 | protein localization to chromosome (GO:0034502) | 3.72920481 |
43 | piRNA metabolic process (GO:0034587) | 3.70187833 |
44 | regulation of centriole replication (GO:0046599) | 3.67976576 |
45 | chromosome segregation (GO:0007059) | 3.65590380 |
46 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 3.61789279 |
47 | regulation of chromosome segregation (GO:0051983) | 3.61454868 |
48 | regulation of mitotic spindle organization (GO:0060236) | 3.60994599 |
49 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 3.57183348 |
50 | regulation of centrosome duplication (GO:0010824) | 3.57137131 |
51 | regulation of centrosome cycle (GO:0046605) | 3.55421475 |
52 | chromatin assembly or disassembly (GO:0006333) | 3.54679408 |
53 | negative regulation of chromosome segregation (GO:0051985) | 3.54140609 |
54 | histone H2A monoubiquitination (GO:0035518) | 3.52484801 |
55 | maturation of 5.8S rRNA (GO:0000460) | 3.51857976 |
56 | pre-miRNA processing (GO:0031054) | 3.51178785 |
57 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 3.50261145 |
58 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 3.50261145 |
59 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 3.50261145 |
60 | negative regulation of sister chromatid segregation (GO:0033046) | 3.50261145 |
61 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 3.49994527 |
62 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 3.49994527 |
63 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 3.49994527 |
64 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 3.48229061 |
65 | spindle assembly checkpoint (GO:0071173) | 3.46981058 |
66 | replication fork processing (GO:0031297) | 3.45544585 |
67 | centriole replication (GO:0007099) | 3.44306318 |
68 | mitotic spindle checkpoint (GO:0071174) | 3.44091799 |
69 | negative regulation of histone methylation (GO:0031061) | 3.42525829 |
70 | telomere maintenance via telomere lengthening (GO:0010833) | 3.41322048 |
71 | mitotic spindle assembly checkpoint (GO:0007094) | 3.40414647 |
72 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.39216861 |
73 | regulation of mitotic sister chromatid segregation (GO:0033047) | 3.35399383 |
74 | regulation of sister chromatid segregation (GO:0033045) | 3.35399383 |
75 | regulation of mitotic sister chromatid separation (GO:0010965) | 3.35399383 |
76 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.34485564 |
77 | regulation of histone H3-K9 methylation (GO:0051570) | 3.33812881 |
78 | ribosome assembly (GO:0042255) | 3.29902785 |
79 | mismatch repair (GO:0006298) | 3.28991810 |
80 | ATP-dependent chromatin remodeling (GO:0043044) | 3.28338861 |
81 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.27317323 |
82 | pore complex assembly (GO:0046931) | 3.26993431 |
83 | nucleobase biosynthetic process (GO:0046112) | 3.25474283 |
84 | nuclear envelope organization (GO:0006998) | 3.22174366 |
85 | negative regulation of meiosis (GO:0045835) | 3.22064527 |
86 | DNA duplex unwinding (GO:0032508) | 3.21492722 |
87 | meiotic cell cycle (GO:0051321) | 3.20398549 |
88 | DNA geometric change (GO:0032392) | 3.20073430 |
89 | negative regulation of retinoic acid receptor signaling pathway (GO:0048387) | 3.16349028 |
90 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 3.15770331 |
91 | sister chromatid cohesion (GO:0007062) | 3.14898034 |
92 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 3.14225085 |
93 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 3.14225085 |
94 | regulation of translation, ncRNA-mediated (GO:0045974) | 3.14225085 |
95 | negative regulation of DNA repair (GO:0045738) | 3.14013987 |
96 | resolution of meiotic recombination intermediates (GO:0000712) | 3.13067952 |
97 | chromosome condensation (GO:0030261) | 3.08768229 |
98 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 3.07724827 |
99 | gene silencing by RNA (GO:0031047) | 3.06215970 |
100 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.05860734 |
101 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.05860734 |
102 | regulation of telomere maintenance via telomerase (GO:0032210) | 3.04223042 |
103 | purine nucleobase biosynthetic process (GO:0009113) | 3.01416294 |
104 | DNA conformation change (GO:0071103) | 3.00021444 |
105 | IMP metabolic process (GO:0046040) | 2.98687615 |
106 | IMP biosynthetic process (GO:0006188) | 2.97367402 |
107 | positive regulation of cell cycle checkpoint (GO:1901978) | 2.94947883 |
108 | double-strand break repair via nonhomologous end joining (GO:0006303) | 2.93186365 |
109 | non-recombinational repair (GO:0000726) | 2.93186365 |
110 | microtubule depolymerization (GO:0007019) | 2.93018047 |
111 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.92537385 |
112 | mitotic cell cycle (GO:0000278) | 2.91029771 |
113 | chromosome organization (GO:0051276) | 2.90278403 |
114 | heterochromatin organization (GO:0070828) | 2.89899496 |
115 | monoubiquitinated protein deubiquitination (GO:0035520) | 2.89692507 |
116 | DNA double-strand break processing (GO:0000729) | 2.85657432 |
117 | DNA ligation (GO:0006266) | 2.82737106 |
118 | paraxial mesoderm development (GO:0048339) | 2.80886448 |
119 | embryonic foregut morphogenesis (GO:0048617) | 2.77363679 |
120 | microtubule anchoring (GO:0034453) | 2.75540111 |
121 | artery development (GO:0060840) | 2.72085037 |
122 | centrosome organization (GO:0051297) | 2.71846462 |
123 | notochord development (GO:0030903) | 2.71621310 |
124 | limb bud formation (GO:0060174) | 2.70749050 |
125 | regulation of RNA export from nucleus (GO:0046831) | 2.70666229 |
126 | microtubule organizing center organization (GO:0031023) | 2.69810024 |
127 | histone H3-K9 methylation (GO:0051567) | 2.66743840 |
128 | centriole assembly (GO:0098534) | 2.64695461 |
129 | DNA packaging (GO:0006323) | 2.63385232 |
130 | centrosome duplication (GO:0051298) | 2.62510705 |
131 | mitotic G2/M transition checkpoint (GO:0044818) | 2.62234658 |
132 | mRNA splice site selection (GO:0006376) | 2.56600618 |
133 | microtubule polymerization or depolymerization (GO:0031109) | 2.54738167 |
134 | DNA synthesis involved in DNA repair (GO:0000731) | 2.53452367 |
135 | regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095) | 2.51912156 |
136 | intra-S DNA damage checkpoint (GO:0031573) | 2.50604907 |
137 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 2.49518668 |
138 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.47927933 |
139 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.47927933 |
140 | negative regulation of mRNA processing (GO:0050686) | 2.45241503 |
141 | regulation of non-canonical Wnt signaling pathway (GO:2000050) | 2.45132376 |
142 | presynaptic membrane assembly (GO:0097105) | 2.43093790 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 5.75825760 |
2 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 4.47031455 |
3 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 4.10396012 |
4 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.65184434 |
5 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.90109885 |
6 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.88425290 |
7 | FUS_26573619_Chip-Seq_HEK293_Human | 2.71744669 |
8 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.62144286 |
9 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.57987156 |
10 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.57361671 |
11 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.54714688 |
12 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.52462159 |
13 | EWS_26573619_Chip-Seq_HEK293_Human | 2.44929115 |
14 | * POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.38769654 |
15 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.37428476 |
16 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.35071710 |
17 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.34944346 |
18 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.32660645 |
19 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.23183004 |
20 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.21815738 |
21 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.21756019 |
22 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.18912657 |
23 | * MYCN_18555785_ChIP-Seq_MESCs_Mouse | 2.08325002 |
24 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.06729604 |
25 | * MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 2.06626464 |
26 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.04307652 |
27 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.04225821 |
28 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.03703219 |
29 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.01248135 |
30 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.00729224 |
31 | E2F7_22180533_ChIP-Seq_HELA_Human | 10.9433800 |
32 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.92240969 |
33 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.91236085 |
34 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.88702307 |
35 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.86679181 |
36 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.81272840 |
37 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.81008579 |
38 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.80209658 |
39 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.77245833 |
40 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.76631766 |
41 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.76151465 |
42 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.73322546 |
43 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.73045144 |
44 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.69424359 |
45 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.68007776 |
46 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.67138719 |
47 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.64501213 |
48 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.63377067 |
49 | * GABP_19822575_ChIP-Seq_HepG2_Human | 1.60608207 |
50 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.58891469 |
51 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.58544574 |
52 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.58496663 |
53 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.58257891 |
54 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.57819593 |
55 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.55006082 |
56 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.53016500 |
57 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.52618502 |
58 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.50504836 |
59 | P300_19829295_ChIP-Seq_ESCs_Human | 1.49703443 |
60 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.48263579 |
61 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.46231246 |
62 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.43827190 |
63 | VDR_22108803_ChIP-Seq_LS180_Human | 1.43437234 |
64 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.41489764 |
65 | MYC_22102868_ChIP-Seq_BL_Human | 1.41324255 |
66 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.39343284 |
67 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.38907260 |
68 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.38907260 |
69 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.38884919 |
70 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.38158626 |
71 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.36979429 |
72 | FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 1.36519747 |
73 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.35484081 |
74 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.33773413 |
75 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.32541244 |
76 | SOX9_26525672_Chip-Seq_HEART_Mouse | 1.32320539 |
77 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.32297531 |
78 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.31559661 |
79 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.31441846 |
80 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.31065240 |
81 | * STAT3_23295773_ChIP-Seq_U87_Human | 1.30374946 |
82 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.30135369 |
83 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.29892579 |
84 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.29424879 |
85 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.28885502 |
86 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.27877570 |
87 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.25945208 |
88 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.24908791 |
89 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.24674637 |
90 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.24105388 |
91 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.22931924 |
92 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.22309197 |
93 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.21899642 |
94 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.21815038 |
95 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.19735699 |
96 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.18566585 |
97 | * NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.18470458 |
98 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.17844324 |
99 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.15474533 |
100 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.14331414 |
101 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.13385218 |
102 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.12882969 |
103 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 1.12504904 |
104 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.12092730 |
105 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.12083966 |
106 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.11948987 |
107 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.11948987 |
108 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 1.11069685 |
109 | TBX3_20139965_ChIP-Seq_ESCs_Mouse | 1.10509400 |
110 | TBX3_20139965_ChIP-Seq_MESCs_Mouse | 1.09787179 |
111 | TCF4_23295773_ChIP-Seq_U87_Human | 1.09767964 |
112 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.09093765 |
113 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 1.08662790 |
114 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.08518203 |
115 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.07173950 |
116 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.06422276 |
117 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.06144662 |
118 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.05264528 |
119 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.05066897 |
120 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.04581509 |
121 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.04518146 |
122 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.04262335 |
123 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.03845002 |
124 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.03408515 |
125 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.02044290 |
126 | TP53_16413492_ChIP-PET_HCT116_Human | 1.01153502 |
127 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.00995010 |
128 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 1.00341275 |
129 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.99102998 |
130 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 0.98548570 |
131 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.98440840 |
132 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.98329641 |
133 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.97968799 |
134 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.97061408 |
135 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.96658189 |
136 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.96434557 |
137 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.95699381 |
138 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.95680597 |
139 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 0.95198727 |
140 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 0.94553581 |
141 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 0.93896339 |
142 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 0.93554418 |
143 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.93460153 |
144 | * RUNX2_22187159_ChIP-Seq_PCA_Human | 0.92252732 |
145 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.92247822 |
146 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 0.91828050 |
147 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.91098184 |
148 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.90500841 |
149 | * ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.89674693 |
150 | AR_25329375_ChIP-Seq_VCAP_Human | 0.88813311 |
151 | POU5F1_18347094_ChIP-ChIP_MESCs_Mouse | 0.88799479 |
152 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.87284232 |
153 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.85869497 |
154 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.85086471 |
155 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 0.84701360 |
156 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 0.84381521 |
157 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.84168329 |
158 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 0.83891425 |
159 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.82974658 |
160 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.82490788 |
161 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.82185904 |
162 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.81775775 |
163 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.79572557 |
164 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.78683400 |
165 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.78259709 |
166 | NANOG_18347094_ChIP-ChIP_MESCs_Mouse | 0.77088924 |
167 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 0.74559098 |
168 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.74327039 |
169 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.72695446 |
170 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.71712071 |
171 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.71426027 |
172 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.68034125 |
173 | * SOX2_18692474_ChIP-Seq_MESCs_Mouse | 0.67051936 |
174 | CHD1_26751641_Chip-Seq_LNCaP_Human | 0.66570018 |
175 | * POU5F1_18692474_ChIP-Seq_MESCs_Mouse | 0.66534613 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0010094_abnormal_chromosome_stability | 5.16471277 |
2 | MP0003693_abnormal_embryo_hatching | 4.88447886 |
3 | MP0003111_abnormal_nucleus_morphology | 4.40686024 |
4 | MP0008057_abnormal_DNA_replication | 4.07244892 |
5 | MP0003077_abnormal_cell_cycle | 4.04525213 |
6 | MP0004957_abnormal_blastocyst_morpholog | 4.00116413 |
7 | MP0008877_abnormal_DNA_methylation | 3.17205608 |
8 | MP0008058_abnormal_DNA_repair | 3.15574369 |
9 | MP0008007_abnormal_cellular_replicative | 2.87622868 |
10 | MP0003718_maternal_effect | 2.80680304 |
11 | MP0008932_abnormal_embryonic_tissue | 2.49064284 |
12 | MP0003123_paternal_imprinting | 2.34690964 |
13 | MP0001730_embryonic_growth_arrest | 2.28665347 |
14 | MP0000350_abnormal_cell_proliferation | 2.25065906 |
15 | MP0010352_gastrointestinal_tract_polyps | 2.14072719 |
16 | MP0002009_preneoplasia | 2.05714382 |
17 | MP0003121_genomic_imprinting | 1.95403202 |
18 | MP0010307_abnormal_tumor_latency | 1.89264209 |
19 | MP0002697_abnormal_eye_size | 1.87415767 |
20 | MP0002653_abnormal_ependyma_morphology | 1.87378925 |
21 | MP0001672_abnormal_embryogenesis/_devel | 1.87198449 |
22 | MP0005380_embryogenesis_phenotype | 1.87198449 |
23 | MP0002210_abnormal_sex_determination | 1.85766579 |
24 | MP0002396_abnormal_hematopoietic_system | 1.83734851 |
25 | MP0001929_abnormal_gametogenesis | 1.82214121 |
26 | MP0003890_abnormal_embryonic-extraembry | 1.81680572 |
27 | MP0002085_abnormal_embryonic_tissue | 1.81451785 |
28 | MP0001697_abnormal_embryo_size | 1.80301688 |
29 | MP0002084_abnormal_developmental_patter | 1.71625164 |
30 | MP0000569_abnormal_digit_pigmentation | 1.69757982 |
31 | MP0003786_premature_aging | 1.69619645 |
32 | MP0000653_abnormal_sex_gland | 1.60615445 |
33 | MP0010030_abnormal_orbit_morphology | 1.60093491 |
34 | MP0003984_embryonic_growth_retardation | 1.57852017 |
35 | MP0001119_abnormal_female_reproductive | 1.55270332 |
36 | MP0000778_abnormal_nervous_system | 1.55041865 |
37 | MP0002088_abnormal_embryonic_growth/wei | 1.54207763 |
38 | MP0003941_abnormal_skin_development | 1.52047454 |
39 | MP0006292_abnormal_olfactory_placode | 1.51265861 |
40 | MP0002233_abnormal_nose_morphology | 1.48574782 |
41 | MP0001145_abnormal_male_reproductive | 1.48110167 |
42 | MP0002080_prenatal_lethality | 1.46855231 |
43 | MP0000537_abnormal_urethra_morphology | 1.45361418 |
44 | MP0000490_abnormal_crypts_of | 1.41296473 |
45 | MP0002086_abnormal_extraembryonic_tissu | 1.40623874 |
46 | MP0003385_abnormal_body_wall | 1.40254391 |
47 | MP0003136_yellow_coat_color | 1.40244228 |
48 | MP0002102_abnormal_ear_morphology | 1.39142728 |
49 | MP0002234_abnormal_pharynx_morphology | 1.36712850 |
50 | MP0004808_abnormal_hematopoietic_stem | 1.36311109 |
51 | MP0003937_abnormal_limbs/digits/tail_de | 1.34711934 |
52 | MP0002019_abnormal_tumor_incidence | 1.33957535 |
53 | MP0000313_abnormal_cell_death | 1.31789882 |
54 | MP0003787_abnormal_imprinting | 1.30728428 |
55 | MP0001299_abnormal_eye_distance/ | 1.28728117 |
56 | MP0003699_abnormal_female_reproductive | 1.28579682 |
57 | MP0002751_abnormal_autonomic_nervous | 1.28176568 |
58 | MP0000383_abnormal_hair_follicle | 1.28137594 |
59 | MP0004197_abnormal_fetal_growth/weight/ | 1.27920581 |
60 | MP0003283_abnormal_digestive_organ | 1.25473846 |
61 | MP0005076_abnormal_cell_differentiation | 1.23726375 |
62 | MP0009250_abnormal_appendicular_skeleto | 1.21390351 |
63 | MP0000631_abnormal_neuroendocrine_gland | 1.20846129 |
64 | MP0003567_abnormal_fetal_cardiomyocyte | 1.17727450 |
65 | MP0003942_abnormal_urinary_system | 1.16660482 |
66 | MP0000049_abnormal_middle_ear | 1.16004976 |
67 | MP0005171_absent_coat_pigmentation | 1.15495199 |
68 | MP0003115_abnormal_respiratory_system | 1.11803257 |
69 | MP0005187_abnormal_penis_morphology | 1.11634664 |
70 | MP0001293_anophthalmia | 1.11390582 |
71 | MP0009053_abnormal_anal_canal | 1.09311340 |
72 | MP0005503_abnormal_tendon_morphology | 1.08386765 |
73 | MP0008995_early_reproductive_senescence | 1.07083175 |
74 | MP0003315_abnormal_perineum_morphology | 1.05937344 |
75 | MP0000534_abnormal_ureter_morphology | 1.04781296 |
76 | MP0002109_abnormal_limb_morphology | 1.02659991 |
77 | MP0005395_other_phenotype | 1.01692501 |
78 | MP0009384_cardiac_valve_regurgitation | 1.00465343 |
79 | MP0003938_abnormal_ear_development | 1.00335010 |
80 | MP0002161_abnormal_fertility/fecundity | 1.00163083 |
81 | MP0003119_abnormal_digestive_system | 0.99260620 |
82 | MP0002249_abnormal_larynx_morphology | 0.98977286 |
83 | MP0005248_abnormal_Harderian_gland | 0.97928431 |
84 | MP0000427_abnormal_hair_cycle | 0.97606585 |
85 | MP0004264_abnormal_extraembryonic_tissu | 0.97195155 |
86 | MP0005391_vision/eye_phenotype | 0.97115375 |
87 | MP0003698_abnormal_male_reproductive | 0.96611663 |
88 | MP0000647_abnormal_sebaceous_gland | 0.94399077 |
89 | MP0003943_abnormal_hepatobiliary_system | 0.94058543 |
90 | MP0002081_perinatal_lethality | 0.93396771 |
91 | MP0005451_abnormal_body_composition | 0.92108924 |
92 | MP0001915_intracranial_hemorrhage | 0.91201436 |
93 | MP0002184_abnormal_innervation | 0.88124836 |
94 | MP0005397_hematopoietic_system_phenotyp | 0.87496809 |
95 | MP0001545_abnormal_hematopoietic_system | 0.87496809 |
96 | MP0003763_abnormal_thymus_physiology | 0.86899031 |
97 | MP0003705_abnormal_hypodermis_morpholog | 0.86862226 |
98 | MP0010678_abnormal_skin_adnexa | 0.86097528 |
99 | MP0003880_abnormal_central_pattern | 0.84338446 |
100 | MP0000703_abnormal_thymus_morphology | 0.83326235 |
101 | MP0004133_heterotaxia | 0.83061175 |
102 | MP0001177_atelectasis | 0.82574953 |
103 | MP0005389_reproductive_system_phenotype | 0.81816000 |
104 | MP0002111_abnormal_tail_morphology | 0.80389759 |
105 | MP0008789_abnormal_olfactory_epithelium | 0.80375836 |
106 | MP0005384_cellular_phenotype | 0.79930648 |
107 | MP0005621_abnormal_cell_physiology | 0.79365981 |
108 | MP0002160_abnormal_reproductive_system | 0.79334098 |
109 | MP0002152_abnormal_brain_morphology | 0.79301237 |
110 | MP0001286_abnormal_eye_development | 0.77353965 |
111 | MP0000432_abnormal_head_morphology | 0.77344126 |
112 | MP0000566_synostosis | 0.76593689 |
113 | MP0003935_abnormal_craniofacial_develop | 0.74445906 |
114 | MP0001919_abnormal_reproductive_system | 0.72945193 |
115 | MP0005023_abnormal_wound_healing | 0.71348544 |
116 | MP0003755_abnormal_palate_morphology | 0.69935555 |
117 | MP0001849_ear_inflammation | 0.69805314 |
118 | MP0009672_abnormal_birth_weight | 0.69496496 |
119 | MP0003861_abnormal_nervous_system | 0.69035829 |
120 | MP0009703_decreased_birth_body | 0.67855560 |
121 | MP0006072_abnormal_retinal_apoptosis | 0.67609866 |
122 | MP0002938_white_spotting | 0.66323852 |
123 | MP0009697_abnormal_copulation | 0.66196865 |
124 | MP0002932_abnormal_joint_morphology | 0.65300707 |
125 | MP0002925_abnormal_cardiovascular_devel | 0.65119631 |
126 | MP0002398_abnormal_bone_marrow | 0.64969596 |
127 | MP0002114_abnormal_axial_skeleton | 0.64276322 |
128 | MP0003221_abnormal_cardiomyocyte_apopto | 0.62841806 |
129 | MP0003566_abnormal_cell_adhesion | 0.61287142 |
130 | MP0000689_abnormal_spleen_morphology | 0.61047454 |
131 | MP0002722_abnormal_immune_system | 0.60759867 |
132 | MP0005408_hypopigmentation | 0.59559741 |
133 | MP0002092_abnormal_eye_morphology | 0.58484924 |
134 | MP0003806_abnormal_nucleotide_metabolis | 0.57880928 |
135 | MP0002282_abnormal_trachea_morphology | 0.57675934 |
136 | MP0000358_abnormal_cell_content/ | 0.57475769 |
137 | MP0003646_muscle_fatigue | 0.57004944 |
138 | MP0002116_abnormal_craniofacial_bone | 0.54652723 |
139 | MP0000428_abnormal_craniofacial_morphol | 0.54160097 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Birth length less than 3rd percentile (HP:0003561) | 5.51749016 |
2 | Chromsome breakage (HP:0040012) | 5.23673169 |
3 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 4.92214860 |
4 | Breast hypoplasia (HP:0003187) | 4.01277100 |
5 | Patellar aplasia (HP:0006443) | 3.80162387 |
6 | Abnormality of chromosome stability (HP:0003220) | 3.77089417 |
7 | Abnormality of the labia minora (HP:0012880) | 3.62367532 |
8 | Medulloblastoma (HP:0002885) | 3.52452695 |
9 | Aplasia/Hypoplasia of the patella (HP:0006498) | 3.46205651 |
10 | Meckel diverticulum (HP:0002245) | 3.38272955 |
11 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 3.34945528 |
12 | Abnormality of the preputium (HP:0100587) | 3.32122494 |
13 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 3.28672899 |
14 | Rhabdomyosarcoma (HP:0002859) | 3.24772430 |
15 | Supernumerary spleens (HP:0009799) | 3.23948152 |
16 | Abnormality of the ileum (HP:0001549) | 3.22090906 |
17 | Ependymoma (HP:0002888) | 3.20225589 |
18 | Myelodysplasia (HP:0002863) | 3.11024456 |
19 | Ectopic kidney (HP:0000086) | 3.04061546 |
20 | Duodenal stenosis (HP:0100867) | 3.04042991 |
21 | Small intestinal stenosis (HP:0012848) | 3.04042991 |
22 | Impulsivity (HP:0100710) | 3.02672470 |
23 | Male infertility (HP:0003251) | 3.01066366 |
24 | Selective tooth agenesis (HP:0001592) | 2.90973534 |
25 | Absent radius (HP:0003974) | 2.83571793 |
26 | Sloping forehead (HP:0000340) | 2.83352046 |
27 | Papillary thyroid carcinoma (HP:0002895) | 2.77208970 |
28 | Colon cancer (HP:0003003) | 2.76936973 |
29 | Facial hemangioma (HP:0000329) | 2.70425487 |
30 | Aplasia involving forearm bones (HP:0009822) | 2.68620309 |
31 | Absent forearm bone (HP:0003953) | 2.68620309 |
32 | Premature ovarian failure (HP:0008209) | 2.66055914 |
33 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.62598255 |
34 | Oral leukoplakia (HP:0002745) | 2.57510071 |
35 | Embryonal renal neoplasm (HP:0011794) | 2.50203616 |
36 | Abnormality of the duodenum (HP:0002246) | 2.49335127 |
37 | Reticulocytopenia (HP:0001896) | 2.49308599 |
38 | Shawl scrotum (HP:0000049) | 2.48729390 |
39 | Aplastic anemia (HP:0001915) | 2.48207289 |
40 | Abnormality of the carotid arteries (HP:0005344) | 2.47023045 |
41 | Neoplasm of striated muscle (HP:0009728) | 2.45582527 |
42 | Abnormal lung lobation (HP:0002101) | 2.45537637 |
43 | Volvulus (HP:0002580) | 2.42877382 |
44 | Agnosia (HP:0010524) | 2.39220642 |
45 | Bone marrow hypocellularity (HP:0005528) | 2.37215194 |
46 | Increased nuchal translucency (HP:0010880) | 2.37181484 |
47 | High anterior hairline (HP:0009890) | 2.37175592 |
48 | Cafe-au-lait spot (HP:0000957) | 2.33700545 |
49 | Abnormality of the renal collecting system (HP:0004742) | 2.28957691 |
50 | Short thumb (HP:0009778) | 2.28235115 |
51 | Absent thumb (HP:0009777) | 2.28210919 |
52 | Acute myeloid leukemia (HP:0004808) | 2.26879729 |
53 | Abnormality of the fingertips (HP:0001211) | 2.26352905 |
54 | Neoplasm of the oral cavity (HP:0100649) | 2.25802677 |
55 | Lip pit (HP:0100267) | 2.24715445 |
56 | Clubbing of toes (HP:0100760) | 2.23574472 |
57 | Astrocytoma (HP:0009592) | 2.23125959 |
58 | Abnormality of the astrocytes (HP:0100707) | 2.23125959 |
59 | Intestinal atresia (HP:0011100) | 2.19356958 |
60 | Midline defect of the nose (HP:0004122) | 2.18743542 |
61 | Sandal gap (HP:0001852) | 2.17650126 |
62 | Rib fusion (HP:0000902) | 2.16941281 |
63 | Abnormality of cochlea (HP:0000375) | 2.15782638 |
64 | Duplicated collecting system (HP:0000081) | 2.14090230 |
65 | Tubulointerstitial nephritis (HP:0001970) | 2.11550447 |
66 | Breast aplasia (HP:0100783) | 2.09669761 |
67 | Horseshoe kidney (HP:0000085) | 2.08720827 |
68 | Carpal bone hypoplasia (HP:0001498) | 2.07770011 |
69 | Degeneration of anterior horn cells (HP:0002398) | 2.06080817 |
70 | Abnormality of the anterior horn cell (HP:0006802) | 2.06080817 |
71 | Cutaneous finger syndactyly (HP:0010554) | 2.04550530 |
72 | Sparse lateral eyebrow (HP:0005338) | 2.02243263 |
73 | Atresia of the external auditory canal (HP:0000413) | 2.01028501 |
74 | Esophageal atresia (HP:0002032) | 2.00447836 |
75 | Capillary hemangiomas (HP:0005306) | 2.00026094 |
76 | Abnormality of abdominal situs (HP:0011620) | 1.98420291 |
77 | Abdominal situs inversus (HP:0003363) | 1.98420291 |
78 | Aplasia/Hypoplasia of the breasts (HP:0010311) | 1.96887916 |
79 | Secondary amenorrhea (HP:0000869) | 1.96353543 |
80 | Tracheoesophageal fistula (HP:0002575) | 1.93403087 |
81 | Glioma (HP:0009733) | 1.92591927 |
82 | Bifid tongue (HP:0010297) | 1.92314438 |
83 | Oligodactyly (HP:0012165) | 1.92265234 |
84 | Gastrointestinal atresia (HP:0002589) | 1.92108959 |
85 | Neoplasm of the pancreas (HP:0002894) | 1.91776096 |
86 | High pitched voice (HP:0001620) | 1.90472509 |
87 | Abnormality of chromosome segregation (HP:0002916) | 1.88980360 |
88 | Abnormality of the ischium (HP:0003174) | 1.88961670 |
89 | Duplication of thumb phalanx (HP:0009942) | 1.88453238 |
90 | Cortical dysplasia (HP:0002539) | 1.86780920 |
91 | Arteriovenous malformation (HP:0100026) | 1.85728839 |
92 | Aqueductal stenosis (HP:0002410) | 1.85278398 |
93 | Neoplasm of the colon (HP:0100273) | 1.84363317 |
94 | Nephronophthisis (HP:0000090) | 1.84103630 |
95 | Cutaneous syndactyly (HP:0012725) | 1.83360983 |
96 | Abnormality of DNA repair (HP:0003254) | 1.82933481 |
97 | Deviation of the thumb (HP:0009603) | 1.82921000 |
98 | Triphalangeal thumb (HP:0001199) | 1.82900743 |
99 | Anophthalmia (HP:0000528) | 1.81472573 |
100 | Bilateral microphthalmos (HP:0007633) | 1.81325166 |
101 | Prominent nose (HP:0000448) | 1.80994962 |
102 | Oligodactyly (hands) (HP:0001180) | 1.80784251 |
103 | Acute lymphatic leukemia (HP:0006721) | 1.80585013 |
104 | Short 4th metacarpal (HP:0010044) | 1.80437430 |
105 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 1.80437430 |
106 | Slender long bone (HP:0003100) | 1.79574639 |
107 | Hypoplastic labia majora (HP:0000059) | 1.79299892 |
108 | Biliary tract neoplasm (HP:0100574) | 1.78578138 |
109 | Overlapping toe (HP:0001845) | 1.78402155 |
110 | Adrenal hypoplasia (HP:0000835) | 1.77585692 |
111 | Chronic hepatic failure (HP:0100626) | 1.77462409 |
112 | 11 pairs of ribs (HP:0000878) | 1.77206930 |
113 | Missing ribs (HP:0000921) | 1.77001493 |
114 | Astigmatism (HP:0000483) | 1.76749748 |
115 | Microretrognathia (HP:0000308) | 1.76084929 |
116 | Heterotopia (HP:0002282) | 1.75909480 |
117 | Preaxial foot polydactyly (HP:0001841) | 1.75362793 |
118 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.75151668 |
119 | Gastrointestinal carcinoma (HP:0002672) | 1.75151668 |
120 | Basal cell carcinoma (HP:0002671) | 1.74173130 |
121 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.73930991 |
122 | Abnormality of the renal medulla (HP:0100957) | 1.72334297 |
123 | Vaginal atresia (HP:0000148) | 1.67006562 |
124 | Genital tract atresia (HP:0001827) | 1.66978100 |
125 | Truncal obesity (HP:0001956) | 1.66505598 |
126 | Drooling (HP:0002307) | 1.66378119 |
127 | Deep philtrum (HP:0002002) | 1.65648122 |
128 | Hypoplastic ischia (HP:0003175) | 1.60714545 |
129 | Abnormal number of incisors (HP:0011064) | 1.58720279 |
130 | Abnormality of midbrain morphology (HP:0002418) | 1.58522428 |
131 | Molar tooth sign on MRI (HP:0002419) | 1.58522428 |
132 | Preaxial hand polydactyly (HP:0001177) | 1.58353297 |
133 | Renal hypoplasia (HP:0000089) | 1.58286331 |
134 | Pancreatic fibrosis (HP:0100732) | 1.58046316 |
135 | Postaxial foot polydactyly (HP:0001830) | 1.57662922 |
136 | Hypoplastic iliac wings (HP:0002866) | 1.57320142 |
137 | True hermaphroditism (HP:0010459) | 1.56977455 |
138 | Short middle phalanx of finger (HP:0005819) | 1.56515703 |
139 | Hyperventilation (HP:0002883) | 1.56283590 |
140 | Abnormality of the 4th metacarpal (HP:0010012) | 1.56160235 |
141 | Poor coordination (HP:0002370) | 1.56157406 |
142 | Obsessive-compulsive behavior (HP:0000722) | 1.55621348 |
143 | Hepatoblastoma (HP:0002884) | 1.54968350 |
144 | Large earlobe (HP:0009748) | 1.54061393 |
145 | Cystic hygroma (HP:0000476) | 1.53692200 |
146 | Pancreatic cysts (HP:0001737) | 1.53431371 |
147 | Protruding tongue (HP:0010808) | 1.52722714 |
148 | Morphological abnormality of the middle ear (HP:0008609) | 1.50733670 |
Rank | Gene Set | Z-score |
---|---|---|
1 | CDC7 | 5.52736789 |
2 | TTK | 3.91964152 |
3 | PLK4 | 3.53373626 |
4 | WEE1 | 3.46982524 |
5 | NEK2 | 3.10542390 |
6 | BUB1 | 2.94542335 |
7 | EEF2K | 2.74877110 |
8 | PNCK | 2.62254682 |
9 | CDK12 | 2.42692925 |
10 | NEK1 | 2.37654405 |
11 | PLK1 | 2.29080634 |
12 | FRK | 2.24080976 |
13 | LATS1 | 2.23154301 |
14 | CASK | 2.17824058 |
15 | ACVR1B | 2.04943255 |
16 | CHEK2 | 2.03401361 |
17 | CAMK1G | 1.99119524 |
18 | MAP3K6 | 1.97376973 |
19 | EIF2AK1 | 1.95022443 |
20 | STK38L | 1.89543587 |
21 | BRAF | 1.87888546 |
22 | STK10 | 1.85809822 |
23 | MAP3K10 | 1.85629910 |
24 | FGFR2 | 1.85171700 |
25 | ATR | 1.84948737 |
26 | RPS6KB2 | 1.76840282 |
27 | AURKB | 1.76456797 |
28 | CDK7 | 1.74398460 |
29 | SRPK1 | 1.71992668 |
30 | BRSK2 | 1.70361370 |
31 | AKT3 | 1.69397710 |
32 | MAP3K8 | 1.61825424 |
33 | LATS2 | 1.58633809 |
34 | MAP3K4 | 1.55525838 |
35 | PLK3 | 1.51184513 |
36 | CAMK1D | 1.48075983 |
37 | CHEK1 | 1.45411584 |
38 | BMPR1B | 1.42654902 |
39 | CDK8 | 1.39169167 |
40 | MELK | 1.36040470 |
41 | TAF1 | 1.35545333 |
42 | MOS | 1.33954802 |
43 | STK3 | 1.26636252 |
44 | WNK3 | 1.26157596 |
45 | TAOK3 | 1.24819267 |
46 | ATM | 1.21725424 |
47 | AURKA | 1.20908489 |
48 | BCR | 1.20353728 |
49 | CDK4 | 1.19736210 |
50 | VRK1 | 1.15317756 |
51 | RAF1 | 1.14175072 |
52 | CDK3 | 1.14022719 |
53 | MKNK1 | 1.13956828 |
54 | PASK | 1.13411042 |
55 | TGFBR1 | 1.11922956 |
56 | STK39 | 1.09516552 |
57 | TNIK | 1.07686412 |
58 | BRSK1 | 1.04218434 |
59 | TSSK6 | 1.03383100 |
60 | KSR2 | 1.02488535 |
61 | DYRK3 | 1.00432825 |
62 | PDGFRA | 0.97361005 |
63 | ERBB4 | 0.96890835 |
64 | ERBB3 | 0.96763316 |
65 | RPS6KA4 | 0.95306219 |
66 | MAPKAPK3 | 0.94871945 |
67 | CDK2 | 0.92797444 |
68 | BRD4 | 0.92149141 |
69 | PBK | 0.90679326 |
70 | FGFR1 | 0.89863447 |
71 | EPHA2 | 0.85947840 |
72 | MARK1 | 0.84797314 |
73 | STK4 | 0.84412675 |
74 | KSR1 | 0.80026581 |
75 | MAP3K9 | 0.79679783 |
76 | CDK1 | 0.78874667 |
77 | SCYL2 | 0.78699453 |
78 | PLK2 | 0.76674373 |
79 | EIF2AK3 | 0.70699865 |
80 | MKNK2 | 0.70141793 |
81 | DYRK2 | 0.69923938 |
82 | CDK6 | 0.67335964 |
83 | ZAK | 0.67204740 |
84 | TESK2 | 0.66229193 |
85 | MAP2K7 | 0.66155878 |
86 | CDK9 | 0.64952670 |
87 | INSRR | 0.64924799 |
88 | PKN2 | 0.64592463 |
89 | PIM1 | 0.63844115 |
90 | EIF2AK2 | 0.62764516 |
91 | EPHA4 | 0.61459786 |
92 | YES1 | 0.61158700 |
93 | DYRK1A | 0.59386281 |
94 | MAP3K13 | 0.55780837 |
95 | MAP4K2 | 0.52787112 |
96 | EPHB2 | 0.52085603 |
97 | PAK4 | 0.51649465 |
98 | BMPR2 | 0.51001915 |
99 | NUAK1 | 0.50737395 |
100 | FLT3 | 0.49073652 |
101 | TRIM28 | 0.48753526 |
102 | MET | 0.48223606 |
103 | MTOR | 0.48046583 |
104 | WNK4 | 0.46284281 |
105 | NTRK2 | 0.46010333 |
106 | TYRO3 | 0.44531486 |
107 | NEK9 | 0.44366077 |
108 | CSNK1D | 0.43787698 |
109 | ERBB2 | 0.43647152 |
110 | PAK1 | 0.43279584 |
111 | PDK3 | 0.42376793 |
112 | PDK4 | 0.42376793 |
113 | TEC | 0.42137652 |
114 | WNK1 | 0.42086625 |
115 | PIK3CA | 0.41822223 |
116 | CSNK2A1 | 0.41690737 |
117 | CSNK2A2 | 0.40147399 |
118 | PRKD3 | 0.40034229 |
119 | PRKDC | 0.38917566 |
120 | CCNB1 | 0.38234282 |
121 | MAPKAPK5 | 0.36952303 |
122 | CSNK1A1L | 0.35924361 |
123 | ARAF | 0.33773159 |
124 | MAP4K1 | 0.33373610 |
125 | MAPK14 | 0.33225494 |
126 | AKT1 | 0.32728393 |
127 | ALK | 0.32334227 |
128 | PRKCI | 0.32162853 |
129 | CSNK1E | 0.31882541 |
130 | MAPK11 | 0.29995083 |
131 | MUSK | 0.28753884 |
132 | CSNK1G1 | 0.27646668 |
133 | TRPM7 | 0.27558852 |
134 | LRRK2 | 0.25568597 |
135 | GSK3B | 0.25318797 |
136 | CSNK1G3 | 0.24555255 |
137 | MAPK13 | 0.23861496 |
138 | MAPK1 | 0.23782489 |
139 | MAP3K5 | 0.23108021 |
140 | NLK | 0.21900795 |
141 | AKT2 | 0.21619054 |
142 | TAOK1 | 0.19758149 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 4.91988457 |
2 | Mismatch repair_Homo sapiens_hsa03430 | 4.38058787 |
3 | Homologous recombination_Homo sapiens_hsa03440 | 3.71375708 |
4 | Cell cycle_Homo sapiens_hsa04110 | 3.68368271 |
5 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.37990404 |
6 | Base excision repair_Homo sapiens_hsa03410 | 3.28785290 |
7 | RNA transport_Homo sapiens_hsa03013 | 3.18954828 |
8 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 3.14048116 |
9 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.93714654 |
10 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.83003879 |
11 | RNA degradation_Homo sapiens_hsa03018 | 2.78180149 |
12 | Spliceosome_Homo sapiens_hsa03040 | 2.77066967 |
13 | Basal transcription factors_Homo sapiens_hsa03022 | 2.60383544 |
14 | RNA polymerase_Homo sapiens_hsa03020 | 2.45223251 |
15 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.29923705 |
16 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.02430692 |
17 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.99446867 |
18 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.99164789 |
19 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.93387755 |
20 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.54924564 |
21 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.40836734 |
22 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.39427859 |
23 | Proteasome_Homo sapiens_hsa03050 | 1.38144323 |
24 | Ribosome_Homo sapiens_hsa03010 | 1.32279974 |
25 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.25038442 |
26 | Purine metabolism_Homo sapiens_hsa00230 | 1.19707962 |
27 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.18892829 |
28 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.10537215 |
29 | Taste transduction_Homo sapiens_hsa04742 | 1.09480926 |
30 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.05386331 |
31 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.05321808 |
32 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.02790768 |
33 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.02656040 |
34 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.00637322 |
35 | Thyroid cancer_Homo sapiens_hsa05216 | 0.96752248 |
36 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.94654123 |
37 | HTLV-I infection_Homo sapiens_hsa05166 | 0.94462654 |
38 | Axon guidance_Homo sapiens_hsa04360 | 0.90542835 |
39 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.90248542 |
40 | Colorectal cancer_Homo sapiens_hsa05210 | 0.89061521 |
41 | Nicotine addiction_Homo sapiens_hsa05033 | 0.86778306 |
42 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.83957818 |
43 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.81992617 |
44 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.81149050 |
45 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.78162030 |
46 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.77109452 |
47 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.75085579 |
48 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.74311890 |
49 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.73362025 |
50 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.71603829 |
51 | Protein export_Homo sapiens_hsa03060 | 0.70588222 |
52 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.69460723 |
53 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.69287983 |
54 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.69250623 |
55 | Glioma_Homo sapiens_hsa05214 | 0.68579138 |
56 | Melanogenesis_Homo sapiens_hsa04916 | 0.68082194 |
57 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.67744781 |
58 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.67711341 |
59 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.61528208 |
60 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.59943480 |
61 | Adherens junction_Homo sapiens_hsa04520 | 0.58900647 |
62 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.58603485 |
63 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.58123292 |
64 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.56286905 |
65 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.56063345 |
66 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.55086491 |
67 | Hepatitis B_Homo sapiens_hsa05161 | 0.54228648 |
68 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.54061839 |
69 | Phototransduction_Homo sapiens_hsa04744 | 0.54028252 |
70 | Olfactory transduction_Homo sapiens_hsa04740 | 0.53698560 |
71 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.52726920 |
72 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.50813068 |
73 | Circadian rhythm_Homo sapiens_hsa04710 | 0.48537711 |
74 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.48235224 |
75 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.48166592 |
76 | Bladder cancer_Homo sapiens_hsa05219 | 0.47662853 |
77 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.47390630 |
78 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.45376485 |
79 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.45198217 |
80 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.45110263 |
81 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.45026133 |
82 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.44379333 |
83 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.44371880 |
84 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.44163977 |
85 | Lysine degradation_Homo sapiens_hsa00310 | 0.43888889 |
86 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.43769552 |
87 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.42835008 |
88 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.42609630 |
89 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.42143087 |
90 | Focal adhesion_Homo sapiens_hsa04510 | 0.41952423 |
91 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.41525676 |
92 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.40695731 |
93 | Pathways in cancer_Homo sapiens_hsa05200 | 0.39366271 |
94 | Endometrial cancer_Homo sapiens_hsa05213 | 0.39288504 |
95 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.37769093 |
96 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.36550210 |
97 | ABC transporters_Homo sapiens_hsa02010 | 0.36480338 |
98 | Cocaine addiction_Homo sapiens_hsa05030 | 0.35965359 |
99 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.35717175 |
100 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.35257314 |
101 | Long-term depression_Homo sapiens_hsa04730 | 0.35164419 |
102 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.34901561 |
103 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.34840623 |
104 | Apoptosis_Homo sapiens_hsa04210 | 0.34593687 |
105 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.34137488 |
106 | Gap junction_Homo sapiens_hsa04540 | 0.34030036 |
107 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.33369709 |
108 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.33173633 |
109 | Prostate cancer_Homo sapiens_hsa05215 | 0.31903074 |
110 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.31776422 |
111 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.30862277 |
112 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.29963644 |
113 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.29925122 |
114 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.29531316 |
115 | Alcoholism_Homo sapiens_hsa05034 | 0.28556954 |
116 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.28233960 |
117 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.28232949 |
118 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.27800684 |
119 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.27528153 |
120 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.27093400 |
121 | Shigellosis_Homo sapiens_hsa05131 | 0.26350685 |
122 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.25793281 |
123 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.23910253 |
124 | Measles_Homo sapiens_hsa05162 | 0.23681391 |
125 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.22726953 |
126 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.22055147 |
127 | Tight junction_Homo sapiens_hsa04530 | 0.21588752 |
128 | Influenza A_Homo sapiens_hsa05164 | 0.20919296 |
129 | Legionellosis_Homo sapiens_hsa05134 | 0.20771510 |
130 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.19568393 |
131 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.19276597 |
132 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.18432781 |
133 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.18034782 |
134 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.16727936 |
135 | Melanoma_Homo sapiens_hsa05218 | 0.16719600 |
136 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.14873793 |
137 | Viral myocarditis_Homo sapiens_hsa05416 | 0.13737268 |
138 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.13318786 |
139 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.11998654 |
140 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.11950436 |
141 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.11329072 |
142 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.11155969 |
143 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.10762248 |