CCDC144B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of cytosolic calcium ion concentration (GO:0051481)8.02378318
2behavioral response to ethanol (GO:0048149)6.15015779
3superoxide anion generation (GO:0042554)5.85720072
4negative regulation of calcium ion-dependent exocytosis (GO:0045955)4.78878372
5adult feeding behavior (GO:0008343)4.60812973
6cilium or flagellum-dependent cell motility (GO:0001539)4.49910200
7energy homeostasis (GO:0097009)4.46665111
8regulation of acrosome reaction (GO:0060046)4.37961979
9regulation of protein glycosylation (GO:0060049)4.33094469
10indolalkylamine metabolic process (GO:0006586)4.16072317
11monoubiquitinated protein deubiquitination (GO:0035520)4.08566541
12tryptophan catabolic process (GO:0006569)3.95026052
13indole-containing compound catabolic process (GO:0042436)3.95026052
14indolalkylamine catabolic process (GO:0046218)3.95026052
15ether lipid metabolic process (GO:0046485)3.88540347
16mesenchymal cell differentiation involved in kidney development (GO:0072161)3.86729336
17mesenchymal cell differentiation involved in renal system development (GO:2001012)3.86729336
18detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.79893043
19behavioral response to nicotine (GO:0035095)3.73613120
20sphingoid metabolic process (GO:0046519)3.66085533
21detection of light stimulus involved in visual perception (GO:0050908)3.63491476
22detection of light stimulus involved in sensory perception (GO:0050962)3.63491476
23positive regulation of cAMP-mediated signaling (GO:0043950)3.59616803
24positive regulation of interleukin-1 beta secretion (GO:0050718)3.56606519
25establishment of protein localization to Golgi (GO:0072600)3.55650127
26G-protein coupled receptor internalization (GO:0002031)3.52831964
27positive regulation of cellular amide metabolic process (GO:0034250)3.46206703
28kynurenine metabolic process (GO:0070189)3.43232565
29neuronal action potential (GO:0019228)3.41949144
30regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.41728814
31DNA integration (GO:0015074)3.38201508
32signal peptide processing (GO:0006465)3.37646310
33membrane depolarization during action potential (GO:0086010)3.35861480
34tryptophan metabolic process (GO:0006568)3.35211636
35microtubule depolymerization (GO:0007019)3.31268817
36sulfate transport (GO:0008272)3.31041332
37response to host immune response (GO:0052572)3.30799444
38response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.30799444
39replicative senescence (GO:0090399)3.28640542
40kinetochore assembly (GO:0051382)3.27351094
41superoxide metabolic process (GO:0006801)3.26956901
42modulation by virus of host process (GO:0019054)3.26390120
43positive regulation of interleukin-1 secretion (GO:0050716)3.26107225
44neural tube formation (GO:0001841)3.23915070
45motile cilium assembly (GO:0044458)3.22823151
46female gonad development (GO:0008585)3.22000731
47photoreceptor cell maintenance (GO:0045494)3.21305064
48tachykinin receptor signaling pathway (GO:0007217)3.21261964
49DNA strand renaturation (GO:0000733)3.21250818
50epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.17559132
51fucose catabolic process (GO:0019317)3.16883950
52L-fucose metabolic process (GO:0042354)3.16883950
53L-fucose catabolic process (GO:0042355)3.16883950
54adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)3.15147497
55ncRNA catabolic process (GO:0034661)3.13804749
56meiotic chromosome segregation (GO:0045132)3.12915190
57negative regulation of mast cell activation (GO:0033004)3.11421510
58daunorubicin metabolic process (GO:0044597)3.10754852
59polyketide metabolic process (GO:0030638)3.10754852
60doxorubicin metabolic process (GO:0044598)3.10754852
61interkinetic nuclear migration (GO:0022027)3.10061423
62regulation of interleukin-1 beta secretion (GO:0050706)3.07672872
63reflex (GO:0060004)3.05700136
64androgen biosynthetic process (GO:0006702)3.05627469
65gamma-aminobutyric acid transport (GO:0015812)3.05479280
66cAMP catabolic process (GO:0006198)3.03968428
67indole-containing compound metabolic process (GO:0042430)3.03928191
68inner ear receptor stereocilium organization (GO:0060122)2.99348596
69positive regulation of heat generation (GO:0031652)2.98902322
70protein K11-linked deubiquitination (GO:0035871)2.98822895
71dendritic cell chemotaxis (GO:0002407)2.97639512
72RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.97636372
73replication fork processing (GO:0031297)2.97388273
74thyroid hormone metabolic process (GO:0042403)2.97111781
75regulation of establishment of cell polarity (GO:2000114)2.95103545
76detection of other organism (GO:0098543)2.93504712
77cornea development in camera-type eye (GO:0061303)2.91683085
78positive regulation of uterine smooth muscle contraction (GO:0070474)2.91625974
79negative regulation of homotypic cell-cell adhesion (GO:0034111)2.91194899
80cell differentiation involved in metanephros development (GO:0072202)2.91045752
81positive regulation by symbiont of host defense response (GO:0052509)2.89152800
82modulation by symbiont of host defense response (GO:0052031)2.89152800
83modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.89152800
84modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.89152800
85positive regulation by organism of defense response of other organism involved in symbiotic interact2.89152800
86modulation by symbiont of host immune response (GO:0052553)2.89152800
87sphingosine metabolic process (GO:0006670)2.88922745
88centriole assembly (GO:0098534)2.87797184
89polyol transport (GO:0015791)2.85827514
90cyclic nucleotide catabolic process (GO:0009214)2.84679357
91cellular response to ethanol (GO:0071361)2.84308799
92kinetochore organization (GO:0051383)2.83736132
93left/right axis specification (GO:0070986)2.83372496
94snRNA transcription (GO:0009301)2.81612555
95adenosine metabolic process (GO:0046085)2.81259182
96G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.81204355
97cellular ketone body metabolic process (GO:0046950)2.79910797
98proline transport (GO:0015824)2.79238817
99axonemal dynein complex assembly (GO:0070286)2.79238783
100detection of molecule of bacterial origin (GO:0032490)2.79026661
101histone H3-K36 demethylation (GO:0070544)2.78916833
102regulation of glutamate receptor signaling pathway (GO:1900449)2.78674563
103detection of bacterium (GO:0016045)2.78353767
104histone H3-K9 methylation (GO:0051567)2.77260943
105histone H3-K9 modification (GO:0061647)2.76454245
106positive regulation of fatty acid transport (GO:2000193)2.76196698
107dendritic cell migration (GO:0036336)2.75891675
108negative regulation of nitric oxide biosynthetic process (GO:0045019)2.75442542
109protein K48-linked deubiquitination (GO:0071108)2.74892770
110sulfate transmembrane transport (GO:1902358)2.72266428
111regulation of female receptivity (GO:0045924)2.71971641
112regulation of cAMP-mediated signaling (GO:0043949)2.71514597
113negative regulation of osteoblast proliferation (GO:0033689)2.71273221
114response to host (GO:0075136)2.71084314
115response to host defenses (GO:0052200)2.71084314
116response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.71084314
117regulation of memory T cell differentiation (GO:0043380)2.70907414
118regulation of activation of Janus kinase activity (GO:0010533)2.70047570
119dentate gyrus development (GO:0021542)2.69979708
120thrombin receptor signaling pathway (GO:0070493)2.69901320
121negative regulation of cAMP-mediated signaling (GO:0043951)2.69228790
122pyrimidine dimer repair (GO:0006290)2.69023698
123negative regulation of adenylate cyclase activity (GO:0007194)2.68954157
124negative regulation of DNA-dependent DNA replication (GO:2000104)2.68236215
125protein targeting to Golgi (GO:0000042)2.68178700
126DNA deamination (GO:0045006)2.67583879
127DNA methylation involved in gamete generation (GO:0043046)2.67445750
128cellular response to gamma radiation (GO:0071480)2.66740592
129positive regulation of CREB transcription factor activity (GO:0032793)2.65908896
130positive regulation of developmental pigmentation (GO:0048087)2.65765231
131NAD biosynthetic process (GO:0009435)2.64669775
132regulation of establishment or maintenance of cell polarity (GO:0032878)2.64404566
133interferon-gamma production (GO:0032609)2.61420072
134modulation by symbiont of host cellular process (GO:0044068)2.61089255
135startle response (GO:0001964)2.60617585
136rRNA catabolic process (GO:0016075)2.59345071
137mesenchymal cell differentiation (GO:0048762)2.57673261
138response to pheromone (GO:0019236)2.57654488
139adaptation of signaling pathway (GO:0023058)2.56719396
140diol metabolic process (GO:0034311)2.56636854
141negative regulation of systemic arterial blood pressure (GO:0003085)2.56561186
142synaptic transmission, glutamatergic (GO:0035249)2.56287272
143negative regulation of keratinocyte proliferation (GO:0010839)2.55927074
144acrosome reaction (GO:0007340)2.55319289
145regulation of platelet aggregation (GO:0090330)2.55150369
146positive regulation of interleukin-1 beta production (GO:0032731)2.54328332
147detection of chemical stimulus involved in sensory perception of smell (GO:0050911)2.53838366
148piRNA metabolic process (GO:0034587)2.53750409
149response to peptidoglycan (GO:0032494)2.52543477
150auditory receptor cell stereocilium organization (GO:0060088)2.51989617
151transmission of nerve impulse (GO:0019226)2.51758305
152retrograde transport, vesicle recycling within Golgi (GO:0000301)2.51756940
153negative regulation of neurotransmitter transport (GO:0051589)2.51357535
154regulation of non-canonical Wnt signaling pathway (GO:2000050)2.51135957
155regulation of interleukin-1 secretion (GO:0050704)2.51005470
156negative regulation of cyclase activity (GO:0031280)2.50565382
157cilium morphogenesis (GO:0060271)2.50444198
158regulation of timing of cell differentiation (GO:0048505)2.50263834
159opioid receptor signaling pathway (GO:0038003)2.50021418
160retinal cone cell development (GO:0046549)2.49537256
161detection of mechanical stimulus involved in sensory perception (GO:0050974)2.49424578
162detection of mechanical stimulus (GO:0050982)2.49346842
163ketone body metabolic process (GO:1902224)2.49195568
164regulation of germinal center formation (GO:0002634)2.49036980
165response to caffeine (GO:0031000)2.48987818
166regulation of pigment cell differentiation (GO:0050932)2.48906025
167double-strand break repair via homologous recombination (GO:0000724)2.48576746
168extracellular regulation of signal transduction (GO:1900115)2.48478157
169extracellular negative regulation of signal transduction (GO:1900116)2.48478157
170synapsis (GO:0007129)2.48289846
171epithelial cilium movement (GO:0003351)2.48183524
172cellular biogenic amine catabolic process (GO:0042402)2.48183103
173amine catabolic process (GO:0009310)2.48183103
174positive regulation of protein sumoylation (GO:0033235)2.46957517
175negative regulation of granulocyte differentiation (GO:0030853)2.46297844
176recombinational repair (GO:0000725)2.45183011
177regulation of sarcomere organization (GO:0060297)2.44791269
178reciprocal DNA recombination (GO:0035825)2.42892451
179reciprocal meiotic recombination (GO:0007131)2.42892451
180negative regulation of myoblast differentiation (GO:0045662)2.42470141
181specification of organ identity (GO:0010092)2.41839027
182regulation of fever generation (GO:0031620)2.41411108
183regulation of glucokinase activity (GO:0033131)2.40941392
184regulation of hexokinase activity (GO:1903299)2.40941392
185regulation of DNA endoreduplication (GO:0032875)2.40607753
186multicellular organism reproduction (GO:0032504)2.37031584
187positive regulation of icosanoid secretion (GO:0032305)2.35524291
188facial nerve structural organization (GO:0021612)2.34768545
189cell proliferation in forebrain (GO:0021846)2.34347976
190cranial nerve structural organization (GO:0021604)2.32141022
191positive regulation of protein homodimerization activity (GO:0090073)2.29995096
192preassembly of GPI anchor in ER membrane (GO:0016254)2.29881958
193detection of external biotic stimulus (GO:0098581)2.29435173

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human3.85281661
2PCGF2_27294783_Chip-Seq_ESCs_Mouse3.25910092
3EZH2_22144423_ChIP-Seq_EOC_Human2.99372946
4ZFP57_27257070_Chip-Seq_ESCs_Mouse2.94507446
5FLI1_27457419_Chip-Seq_LIVER_Mouse2.91813299
6SUZ12_27294783_Chip-Seq_NPCs_Mouse2.69966741
7PCGF2_27294783_Chip-Seq_NPCs_Mouse2.61679956
8NFE2_27457419_Chip-Seq_LIVER_Mouse2.57904467
9ZNF274_21170338_ChIP-Seq_K562_Hela2.52188739
10PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.36823501
11FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.20702195
12EZH2_27294783_Chip-Seq_NPCs_Mouse2.17468005
13GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.16374907
14IGF1R_20145208_ChIP-Seq_DFB_Human2.13625091
15* BMI1_23680149_ChIP-Seq_NPCS_Mouse2.12838294
16SMARCD1_25818293_ChIP-Seq_ESCs_Mouse2.10242515
17TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse2.06774164
18RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.06158793
19EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse2.05238786
20NANOG_18555785_Chip-Seq_ESCs_Mouse2.03172161
21P53_22387025_ChIP-Seq_ESCs_Mouse2.01267875
22POU3F2_20337985_ChIP-ChIP_501MEL_Human2.00588686
23CBX2_27304074_Chip-Seq_ESCs_Mouse1.99718093
24TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.98053669
25E2F1_18555785_Chip-Seq_ESCs_Mouse1.97457797
26SUZ12_18555785_Chip-Seq_ESCs_Mouse1.97119114
27STAT3_18555785_Chip-Seq_ESCs_Mouse1.96011221
28GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.88554551
29NMYC_18555785_Chip-Seq_ESCs_Mouse1.86951827
30EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.86412801
31IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.80983133
32CBP_20019798_ChIP-Seq_JUKART_Human1.80983133
33BCAT_22108803_ChIP-Seq_LS180_Human1.80927206
34SMAD_19615063_ChIP-ChIP_OVARY_Human1.78977763
35P300_18555785_Chip-Seq_ESCs_Mouse1.78309535
36CMYC_18555785_Chip-Seq_ESCs_Mouse1.78230502
37BP1_19119308_ChIP-ChIP_Hs578T_Human1.74715765
38OCT4_18555785_Chip-Seq_ESCs_Mouse1.74125232
39RUNX1_27457419_Chip-Seq_LIVER_Mouse1.73250230
40SOX2_18555785_Chip-Seq_ESCs_Mouse1.71764274
41P300_19829295_ChIP-Seq_ESCs_Human1.71070432
42SALL1_21062744_ChIP-ChIP_HESCs_Human1.70583298
43ZFX_18555785_Chip-Seq_ESCs_Mouse1.67827837
44PU1_27457419_Chip-Seq_LIVER_Mouse1.65785050
45PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.65075811
46ESRRB_18555785_Chip-Seq_ESCs_Mouse1.62898748
47EED_16625203_ChIP-ChIP_MESCs_Mouse1.61331714
48KLF4_18555785_Chip-Seq_ESCs_Mouse1.60401201
49RNF2_27304074_Chip-Seq_NSC_Mouse1.59401239
50TP63_19390658_ChIP-ChIP_HaCaT_Human1.57765986
51ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.56196357
52SMAD4_21799915_ChIP-Seq_A2780_Human1.55152864
53CTCF_18555785_Chip-Seq_ESCs_Mouse1.54838909
54AR_21572438_ChIP-Seq_LNCaP_Human1.53525232
55CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.52438905
56SMAD1_18555785_Chip-Seq_ESCs_Mouse1.51362259
57CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.51240198
58PIAS1_25552417_ChIP-Seq_VCAP_Human1.50039924
59SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.49911042
60JARID2_20064375_ChIP-Seq_MESCs_Mouse1.49715314
61OCT4_21477851_ChIP-Seq_ESCs_Mouse1.49705155
62TAL1_26923725_Chip-Seq_HPCs_Mouse1.49404519
63CRX_20693478_ChIP-Seq_RETINA_Mouse1.47989118
64TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.46999379
65POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.46999379
66FLI1_21867929_ChIP-Seq_TH2_Mouse1.44635413
67CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.44386064
68RXR_22108803_ChIP-Seq_LS180_Human1.43685511
69EZH2_27304074_Chip-Seq_ESCs_Mouse1.43233626
70MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.43227601
71BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.43075047
72VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.41658036
73SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.40482810
74TP53_16413492_ChIP-PET_HCT116_Human1.39710155
75SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.38998161
76SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.36767441
77TAF15_26573619_Chip-Seq_HEK293_Human1.35551363
78MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.35405552
79RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.34719900
80PRDM14_20953172_ChIP-Seq_ESCs_Human1.34011366
81TCF4_22108803_ChIP-Seq_LS180_Human1.33898344
82AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.33792862
83NANOG_19829295_ChIP-Seq_ESCs_Human1.33608001
84SOX2_19829295_ChIP-Seq_ESCs_Human1.33608001
85FUS_26573619_Chip-Seq_HEK293_Human1.32257927
86EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.32159299
87ER_23166858_ChIP-Seq_MCF-7_Human1.31626845
88EWS_26573619_Chip-Seq_HEK293_Human1.31545857
89SMAD3_21741376_ChIP-Seq_EPCs_Human1.30654891
90KDM2B_26808549_Chip-Seq_REH_Human1.30631951
91TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.29708740
92FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.28780454
93CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.28563942
94BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.28174304
95STAT3_23295773_ChIP-Seq_U87_Human1.27053289
96CDX2_19796622_ChIP-Seq_MESCs_Mouse1.27028830
97CTBP2_25329375_ChIP-Seq_LNCAP_Human1.26715443
98* TCF4_23295773_ChIP-Seq_U87_Human1.26275135
99VDR_22108803_ChIP-Seq_LS180_Human1.24762625
100TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.24533744
101IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.22846512
102TP53_22573176_ChIP-Seq_HFKS_Human1.20339056
103OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.20215650
104TOP2B_26459242_ChIP-Seq_MCF-7_Human1.19748650
105TP53_18474530_ChIP-ChIP_U2OS_Human1.19281968
106IRF1_19129219_ChIP-ChIP_H3396_Human1.19018618
107SOX2_21211035_ChIP-Seq_LN229_Gbm1.18994271
108UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.18837835
109TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.17744249
110REST_21632747_ChIP-Seq_MESCs_Mouse1.16739008
111CDX2_22108803_ChIP-Seq_LS180_Human1.16577528
112KAP1_22055183_ChIP-Seq_ESCs_Mouse1.15561372
113RNF2_27304074_Chip-Seq_ESCs_Mouse1.15328991
114CTBP1_25329375_ChIP-Seq_LNCAP_Human1.15320992
115SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.14957608
116RUNX2_22187159_ChIP-Seq_PCA_Human1.14255590
117SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.13568514
118SMAD4_21741376_ChIP-Seq_EPCs_Human1.12968315
119MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.12776894
120KLF5_20875108_ChIP-Seq_MESCs_Mouse1.11931353
121AHR_22903824_ChIP-Seq_MCF-7_Human1.11622970
122EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.11150211
123ARNT_22903824_ChIP-Seq_MCF-7_Human1.10810572
124JARID2_20075857_ChIP-Seq_MESCs_Mouse1.10747102
125EZH2_27294783_Chip-Seq_ESCs_Mouse1.09481860
126CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.09072119
127AR_25329375_ChIP-Seq_VCAP_Human1.08520273
128ZNF217_24962896_ChIP-Seq_MCF-7_Human1.06010924
129NR3C1_21868756_ChIP-Seq_MCF10A_Human1.05162679
130DROSHA_22980978_ChIP-Seq_HELA_Human1.04758505
131IRF8_21731497_ChIP-ChIP_J774_Mouse1.04378209
132RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.04081204
133SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.02796026
134TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98843375
135FOXA1_21572438_ChIP-Seq_LNCaP_Human0.98108396
136SOX9_26525672_Chip-Seq_Limbbuds_Mouse0.95392373
137GATA3_21878914_ChIP-Seq_MCF-7_Human0.94722241
138HTT_18923047_ChIP-ChIP_STHdh_Human0.94062760

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001188_hyperpigmentation4.34969522
2MP0000566_synostosis3.76850953
3MP0002102_abnormal_ear_morphology3.39907406
4MP0006292_abnormal_olfactory_placode3.35199197
5MP0001501_abnormal_sleep_pattern2.89479541
6MP0002277_abnormal_respiratory_mucosa2.82811052
7MP0009780_abnormal_chondrocyte_physiolo2.77403990
8MP0003195_calcinosis2.72406619
9MP0003787_abnormal_imprinting2.64155707
10MP0003646_muscle_fatigue2.57435717
11MP0009697_abnormal_copulation2.45177549
12MP0003136_yellow_coat_color2.44415293
13MP0003880_abnormal_central_pattern2.40860756
14MP0008058_abnormal_DNA_repair2.37967433
15MP0005645_abnormal_hypothalamus_physiol2.30555965
16MP0009278_abnormal_bone_marrow2.24148059
17MP0000015_abnormal_ear_pigmentation2.23337479
18MP0003045_fibrosis2.22124907
19MP0009745_abnormal_behavioral_response2.20610792
20MP0001986_abnormal_taste_sensitivity2.19218286
21MP0000569_abnormal_digit_pigmentation2.16523952
22MP0004043_abnormal_pH_regulation2.09611511
23MP0005171_absent_coat_pigmentation2.07569004
24MP0003941_abnormal_skin_development2.03315041
25MP0002132_abnormal_respiratory_system1.99252858
26MP0004381_abnormal_hair_follicle1.95447669
27MP0002876_abnormal_thyroid_physiology1.93027999
28MP0001835_abnormal_antigen_presentation1.86247783
29MP0004147_increased_porphyrin_level1.81607496
30MP0005451_abnormal_body_composition1.81193527
31MP0002272_abnormal_nervous_system1.80089361
32MP0005646_abnormal_pituitary_gland1.78008018
33MP0005409_darkened_coat_color1.76300113
34MP0002638_abnormal_pupillary_reflex1.74998123
35MP0003633_abnormal_nervous_system1.68563489
36MP0005174_abnormal_tail_pigmentation1.64703507
37MP0008872_abnormal_physiological_respon1.61140441
38MP0002735_abnormal_chemical_nociception1.58125395
39MP0000383_abnormal_hair_follicle1.57028789
40MP0002733_abnormal_thermal_nociception1.50586359
41MP0004742_abnormal_vestibular_system1.50515184
42MP0000372_irregular_coat_pigmentation1.47632072
43MP0002148_abnormal_hypersensitivity_rea1.46651616
44MP0001346_abnormal_lacrimal_gland1.45017058
45MP0002064_seizures1.44871555
46MP0005257_abnormal_intraocular_pressure1.43845730
47MP0003724_increased_susceptibility_to1.42423930
48MP0009785_altered_susceptibility_to1.41791527
49MP0003635_abnormal_synaptic_transmissio1.39808142
50MP0000579_abnormal_nail_morphology1.39679565
51MP0005410_abnormal_fertilization1.39622238
52MP0004142_abnormal_muscle_tone1.37681180
53MP0009764_decreased_sensitivity_to1.37429419
54MP0000026_abnormal_inner_ear1.37395393
55MP0001970_abnormal_pain_threshold1.35654231
56MP0008057_abnormal_DNA_replication1.34852632
57MP0004924_abnormal_behavior1.33384633
58MP0005386_behavior/neurological_phenoty1.33384633
59MP0001486_abnormal_startle_reflex1.32271151
60MP0005670_abnormal_white_adipose1.30451714
61MP0003183_abnormal_peptide_metabolism1.29783752
62MP0008260_abnormal_autophagy1.28291066
63MP0002572_abnormal_emotion/affect_behav1.27854166
64MP0001664_abnormal_digestion1.27527966
65MP0002168_other_aberrant_phenotype1.25808883
66MP0005397_hematopoietic_system_phenotyp1.25013632
67MP0001545_abnormal_hematopoietic_system1.25013632
68MP0005253_abnormal_eye_physiology1.24998279
69MP0002938_white_spotting1.24706966
70MP0004145_abnormal_muscle_electrophysio1.24496298
71MP0008877_abnormal_DNA_methylation1.24422350
72MP0001502_abnormal_circadian_rhythm1.23917814
73MP0005647_abnormal_sex_gland1.22552743
74MP0005360_urolithiasis1.19612711
75MP0005379_endocrine/exocrine_gland_phen1.19340506
76MP0001485_abnormal_pinna_reflex1.19232829
77MP0005310_abnormal_salivary_gland1.18639316
78MP0004782_abnormal_surfactant_physiolog1.18565178
79MP0002095_abnormal_skin_pigmentation1.18492558
80MP0005075_abnormal_melanosome_morpholog1.18080504
81MP0002163_abnormal_gland_morphology1.17616241
82MP0009046_muscle_twitch1.16044360
83MP0003631_nervous_system_phenotype1.15543708
84MP0010386_abnormal_urinary_bladder1.15540950
85MP0006276_abnormal_autonomic_nervous1.15349682
86MP0003950_abnormal_plasma_membrane1.15007767
87MP0000230_abnormal_systemic_arterial1.14628040
88MP0001790_abnormal_immune_system1.14458236
89MP0005387_immune_system_phenotype1.14458236
90MP0001963_abnormal_hearing_physiology1.13399179
91MP0008004_abnormal_stomach_pH1.13148560
92MP0002557_abnormal_social/conspecific_i1.11197834
93MP0004130_abnormal_muscle_cell1.10891925
94MP0002837_dystrophic_cardiac_calcinosis1.09558798
95MP0002063_abnormal_learning/memory/cond1.08641260
96MP0003252_abnormal_bile_duct1.08436782
97MP0000490_abnormal_crypts_of1.06760216
98MP0008995_early_reproductive_senescence1.04447241
99MP0002419_abnormal_innate_immunity1.04258661
100MP0002396_abnormal_hematopoietic_system1.04229861
101MP0006072_abnormal_retinal_apoptosis1.03186878
102MP0002229_neurodegeneration1.02774791
103MP0002736_abnormal_nociception_after1.02556620
104MP0000427_abnormal_hair_cycle1.02343936
105MP0001119_abnormal_female_reproductive0.99419358
106MP0003698_abnormal_male_reproductive0.96104445
107MP0002210_abnormal_sex_determination0.95520904
108MP0005503_abnormal_tendon_morphology0.95384769
109MP0005671_abnormal_response_to0.95066262
110MP0001186_pigmentation_phenotype0.93303656
111MP0005025_abnormal_response_to0.90965744
112MP0003111_abnormal_nucleus_morphology0.90941269
113MP0000049_abnormal_middle_ear0.90089193
114MP0000631_abnormal_neuroendocrine_gland0.89576623
115MP0005167_abnormal_blood-brain_barrier0.89311188
116MP0000538_abnormal_urinary_bladder0.88240707
117MP0002693_abnormal_pancreas_physiology0.86909735
118MP0002138_abnormal_hepatobiliary_system0.86698108
119MP0004885_abnormal_endolymph0.85891098
120MP0001968_abnormal_touch/_nociception0.85193551
121MP0006035_abnormal_mitochondrial_morpho0.84906254
122MP0002249_abnormal_larynx_morphology0.84807568
123MP0002177_abnormal_outer_ear0.84504261
124MP0003938_abnormal_ear_development0.82885911
125MP0010094_abnormal_chromosome_stability0.81999737
126MP0008789_abnormal_olfactory_epithelium0.80774669
127MP0005395_other_phenotype0.80531662
128MP0001984_abnormal_olfaction0.80360804
129MP0005551_abnormal_eye_electrophysiolog0.79616640
130MP0002723_abnormal_immune_serum0.78569744
131MP0005195_abnormal_posterior_eye0.78180312
132MP0000678_abnormal_parathyroid_gland0.77927095
133MP0004859_abnormal_synaptic_plasticity0.77152873
134MP0001800_abnormal_humoral_immune0.77135372
135MP0002452_abnormal_antigen_presenting0.76224086
136MP0002160_abnormal_reproductive_system0.75888849
137MP0002075_abnormal_coat/hair_pigmentati0.74816841
138MP0001929_abnormal_gametogenesis0.74452413
139MP0005389_reproductive_system_phenotype0.72873306
140MP0002928_abnormal_bile_duct0.72294885
141MP0003878_abnormal_ear_physiology0.72025422
142MP0005377_hearing/vestibular/ear_phenot0.72025422
143MP0003879_abnormal_hair_cell0.71454470
144MP0003786_premature_aging0.70370595
145MP0005000_abnormal_immune_tolerance0.69744125
146MP0002109_abnormal_limb_morphology0.69503477
147MP0004019_abnormal_vitamin_homeostasis0.68797530
148MP0000371_diluted_coat_color0.68773364
149MP0002734_abnormal_mechanical_nocicepti0.68622390
150MP0008961_abnormal_basal_metabolism0.68493616
151MP0002098_abnormal_vibrissa_morphology0.68491431
152MP0000681_abnormal_thyroid_gland0.68085395
153MP0002067_abnormal_sensory_capabilities0.67063799
154MP0001819_abnormal_immune_cell0.66640085
155MP0008775_abnormal_heart_ventricle0.66533730
156MP0009250_abnormal_appendicular_skeleto0.65417092
157MP0004085_abnormal_heartbeat0.64213920
158MP0004215_abnormal_myocardial_fiber0.63853181
159MP0001324_abnormal_eye_pigmentation0.63431852
160MP0005266_abnormal_metabolism0.62900277
161MP0002752_abnormal_somatic_nervous0.62717908
162MP0002108_abnormal_muscle_morphology0.61903272

Predicted human phenotypes

RankGene SetZ-score
1Thyroid-stimulating hormone excess (HP:0002925)6.62639920
2Chromosomal breakage induced by crosslinking agents (HP:0003221)6.43157064
3Chromsome breakage (HP:0040012)5.67980402
4Gaze-evoked nystagmus (HP:0000640)4.99569736
5Volvulus (HP:0002580)4.64982085
6Hyperventilation (HP:0002883)4.42097131
7Prostate neoplasm (HP:0100787)4.16919810
8Febrile seizures (HP:0002373)4.13942297
9Genetic anticipation (HP:0003743)4.01078934
10Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.87698015
11Pancreatic cysts (HP:0001737)3.82776477
12Dynein arm defect of respiratory motile cilia (HP:0012255)3.47947164
13Absent/shortened dynein arms (HP:0200106)3.47947164
14Focal seizures (HP:0007359)3.42732485
15Progressive cerebellar ataxia (HP:0002073)3.26393176
16Large for gestational age (HP:0001520)3.23903898
17Attenuation of retinal blood vessels (HP:0007843)3.17316506
18Aplasia/Hypoplasia of the uvula (HP:0010293)3.11451939
19Dialeptic seizures (HP:0011146)3.05910722
20Duplicated collecting system (HP:0000081)3.02414541
21Upper limb muscle weakness (HP:0003484)3.01319439
22Type II lissencephaly (HP:0007260)3.00548029
23Tubular atrophy (HP:0000092)2.99478716
24Abnormality of midbrain morphology (HP:0002418)2.96724177
25Molar tooth sign on MRI (HP:0002419)2.96724177
26Optic neuritis (HP:0100653)2.95178466
27Retrobulbar optic neuritis (HP:0100654)2.95178466
28Broad-based gait (HP:0002136)2.91440350
29Increased corneal curvature (HP:0100692)2.90716534
30Keratoconus (HP:0000563)2.90716534
31Abnormality of the renal collecting system (HP:0004742)2.90615828
32Abnormal ciliary motility (HP:0012262)2.90182129
33Abnormality of the preputium (HP:0100587)2.89315257
34Meckel diverticulum (HP:0002245)2.89148194
35Cerebellar dysplasia (HP:0007033)2.88212990
36Clubbing of toes (HP:0100760)2.86999667
37Abnormality of the ileum (HP:0001549)2.76800828
38Abnormal respiratory motile cilium physiology (HP:0012261)2.75068775
39Chronic hepatic failure (HP:0100626)2.73827799
40Septo-optic dysplasia (HP:0100842)2.72529784
41Congenital stationary night blindness (HP:0007642)2.71284250
42Cystic liver disease (HP:0006706)2.58429800
43Abnormality of DNA repair (HP:0003254)2.58143257
44Clumsiness (HP:0002312)2.56429496
45Renal cortical cysts (HP:0000803)2.54546330
46Abnormality of the aortic arch (HP:0012303)2.52687136
47Osteomalacia (HP:0002749)2.49599425
48Abnormal hair whorl (HP:0010721)2.47939452
49Tubulointerstitial nephritis (HP:0001970)2.46517842
50Atonic seizures (HP:0010819)2.43881079
51Congenital sensorineural hearing impairment (HP:0008527)2.42562866
52Aplasia/Hypoplasia of the fovea (HP:0008060)2.39560527
53Hypoplasia of the fovea (HP:0007750)2.39560527
54Aplasia cutis congenita (HP:0001057)2.39212964
55Focal motor seizures (HP:0011153)2.38265847
56Hypoplasia of the pons (HP:0012110)2.38137910
57Tented upper lip vermilion (HP:0010804)2.36231898
58Abnormality of incisor morphology (HP:0011063)2.35594158
59Abnormality of chromosome stability (HP:0003220)2.35133928
60Abnormal respiratory motile cilium morphology (HP:0005938)2.33883432
61Abnormal respiratory epithelium morphology (HP:0012253)2.33883432
62Ectopic kidney (HP:0000086)2.32957128
63Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.32699111
64Absence seizures (HP:0002121)2.31961389
65Absent speech (HP:0001344)2.31350813
66Decreased electroretinogram (ERG) amplitude (HP:0000654)2.31104231
67Oligodontia (HP:0000677)2.29757796
68Hypothermia (HP:0002045)2.28180741
69Nephronophthisis (HP:0000090)2.25625687
70Thickened helices (HP:0000391)2.24779182
71Abnormality of the prostate (HP:0008775)2.23071244
72Hypoproteinemia (HP:0003075)2.22331297
73Abolished electroretinogram (ERG) (HP:0000550)2.20880378
74True hermaphroditism (HP:0010459)2.20442587
75Alveolar cell carcinoma (HP:0006519)2.19857334
76Abnormality of the pons (HP:0007361)2.19534121
77Abnormality of macular pigmentation (HP:0008002)2.18739078
78Abnormal drinking behavior (HP:0030082)2.18498719
79Polydipsia (HP:0001959)2.18498719
80Mesomelia (HP:0003027)2.16796232
81Protruding tongue (HP:0010808)2.16463837
82Abnormality of the nasal septum (HP:0000419)2.15598028
83Abnormality of the renal medulla (HP:0100957)2.15532632
84Abnormality of the renal cortex (HP:0011035)2.14649490
85Pancreatic islet-cell hyperplasia (HP:0004510)2.14342853
86Central scotoma (HP:0000603)2.13302078
87Inability to walk (HP:0002540)2.11969464
88Median cleft lip (HP:0000161)2.10198723
89Epileptic encephalopathy (HP:0200134)2.09640536
90Orchitis (HP:0100796)2.09507192
91Microvesicular hepatic steatosis (HP:0001414)2.07516864
92Increased neuronal autofluorescent lipopigment (HP:0002074)2.06802562
93Nephroblastoma (Wilms tumor) (HP:0002667)2.05929812
94Optic nerve hypoplasia (HP:0000609)2.05837732
95Duplication of thumb phalanx (HP:0009942)2.05697560
96White forelock (HP:0002211)2.05523366
97Congenital hepatic fibrosis (HP:0002612)2.04709673
98Abnormality of the carotid arteries (HP:0005344)2.03804968
99Fair hair (HP:0002286)2.02994255
100Lip pit (HP:0100267)2.02953360
101Widely spaced teeth (HP:0000687)2.02385904
102Decreased circulating renin level (HP:0003351)2.01756375
103Broad alveolar ridges (HP:0000187)2.01297059
104Progressive inability to walk (HP:0002505)2.01267973
105Conical tooth (HP:0000698)1.99634442
106Lissencephaly (HP:0001339)1.98934491
107Dysdiadochokinesis (HP:0002075)1.98817312
108Bony spicule pigmentary retinopathy (HP:0007737)1.98424012
109Preaxial hand polydactyly (HP:0001177)1.97868025
110Severe visual impairment (HP:0001141)1.97588826
111Postaxial foot polydactyly (HP:0001830)1.97440154
112Patchy hypopigmentation of hair (HP:0011365)1.96902175
113Abnormal biliary tract physiology (HP:0012439)1.96615632
114Bile duct proliferation (HP:0001408)1.96615632
115Abnormal rod and cone electroretinograms (HP:0008323)1.96423794
116Gastrointestinal atresia (HP:0002589)1.95628059
117Recurrent cutaneous fungal infections (HP:0011370)1.95007295
118Chronic mucocutaneous candidiasis (HP:0002728)1.95007295
119Agitation (HP:0000713)1.94457405
120Gait imbalance (HP:0002141)1.92501548
121Mesangial abnormality (HP:0001966)1.91911552
122Embryonal renal neoplasm (HP:0011794)1.89716574
123Recurrent pneumonia (HP:0006532)1.86061312
124Neoplasm of the tracheobronchial system (HP:0100552)1.85790882
125Myositis (HP:0100614)1.85241562
126Male pseudohermaphroditism (HP:0000037)1.84481008
127Decreased central vision (HP:0007663)1.82991093
128Scotoma (HP:0000575)1.82975579
129Generalized hypopigmentation of hair (HP:0011358)1.82469941
130Small intestinal stenosis (HP:0012848)1.81476659
131Duodenal stenosis (HP:0100867)1.81476659
132Medial flaring of the eyebrow (HP:0010747)1.81392171
133Congenital primary aphakia (HP:0007707)1.79156299
134Constricted visual fields (HP:0001133)1.77653834
135Pendular nystagmus (HP:0012043)1.75743007
136Polyuria (HP:0000103)1.74069131
137Astigmatism (HP:0000483)1.72795976
138Bulbous nose (HP:0000414)1.72287520
139Facial cleft (HP:0002006)1.72108363
140Aplasia/Hypoplasia of the tibia (HP:0005772)1.70815747
141Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.69888298
142Poor speech (HP:0002465)1.69868231
143Recurrent sinusitis (HP:0011108)1.68940414
144Long nose (HP:0003189)1.68592941
145Abnormality of the fovea (HP:0000493)1.68308241
146Pancreatic fibrosis (HP:0100732)1.68265930
147Unilateral renal agenesis (HP:0000122)1.68006389
148Furrowed tongue (HP:0000221)1.67986558
149Dysmetric saccades (HP:0000641)1.67625474
150Increased IgM level (HP:0003496)1.67620804
151Hypergonadotropic hypogonadism (HP:0000815)1.67333079
152Chorioretinal atrophy (HP:0000533)1.66804234
153Triphalangeal thumb (HP:0001199)1.65827038
154Oligohydramnios (HP:0001562)1.65769031
155Reduced antithrombin III activity (HP:0001976)1.65177480
156Anal stenosis (HP:0002025)1.65102067
157Absent septum pellucidum (HP:0001331)1.64805436
158Poor head control (HP:0002421)1.64708656
159Genital tract atresia (HP:0001827)1.64559192
160Impaired smooth pursuit (HP:0007772)1.63665286
161Type 2 muscle fiber atrophy (HP:0003554)1.62641356
162Stomach cancer (HP:0012126)1.62419438
163Distal lower limb muscle weakness (HP:0009053)1.61413363
164Abnormality of molar (HP:0011077)1.60661432
165Abnormality of molar morphology (HP:0011070)1.60661432
166Aplasia/Hypoplasia of the lens (HP:0008063)1.59932845
167Submucous cleft hard palate (HP:0000176)1.59485414
168Chronic diarrhea (HP:0002028)1.59294984
169Intestinal atresia (HP:0011100)1.58826327

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK4.26246606
2ZAK3.20882859
3INSRR3.12314756
4TXK3.08162219
5EIF2AK22.93409513
6TNIK2.69779916
7ACVR1B2.66715370
8MAP3K142.60413123
9PRPF4B2.36709653
10MAP2K72.17755145
11YES12.14763316
12IRAK32.07192711
13GRK11.90067430
14MKNK21.87540382
15PINK11.87129192
16ADRBK21.84020712
17ADRBK11.79708646
18STK161.77183039
19PNCK1.70568463
20CDK31.62783632
21BMPR1B1.62619939
22SIK31.62360038
23MUSK1.61257632
24IRAK41.59366963
25TAOK21.57261791
26MAP4K21.55614098
27AKT31.53017302
28WNK31.52492946
29CAMKK21.51206648
30SGK21.49114158
31BRD41.46010706
32NUAK11.45412707
33OXSR11.39215239
34MAPK71.38113038
35TEC1.37009969
36BMPR21.28919100
37STK38L1.28408972
38MAPK131.24194807
39SRPK11.18551870
40TNK21.15783198
41IKBKB1.15721843
42BRSK21.15265209
43MAP3K41.15032316
44PIK3CG1.12417943
45NTRK31.11202121
46NEK61.10379442
47PKN11.08739638
48STK391.07792719
49PRKCG1.06053844
50IKBKE1.04508352
51MKNK11.01109072
52TGFBR10.96807631
53DAPK20.96114903
54PTK2B0.91416544
55EPHA30.90063316
56PLK40.88569754
57VRK10.87328824
58PAK30.86664650
59CLK10.83524191
60CHUK0.83366712
61ERBB30.82341383
62TLK10.81142240
63PIK3CA0.80661444
64JAK10.77070067
65MARK10.75246256
66TIE10.73572084
67CAMK10.72684407
68CAMK2A0.71215328
69SGK30.71088499
70ATR0.70971637
71MAPK110.69942537
72JAK30.69303648
73MAP3K70.68938976
74WNK40.66943105
75SGK4940.66138760
76SGK2230.66138760
77GRK70.65269596
78PRKCE0.64387812
79FRK0.64166255
80TAOK30.62246103
81ITK0.61630903
82FLT30.61444689
83KIT0.59612569
84CCNB10.58369198
85ERBB20.56915704
86STK380.53810321
87CDK80.53369123
88FER0.52303038
89NTRK20.51832942
90SGK10.51544807
91STK240.51202596
92CAMK1G0.51144937
93RPS6KL10.50025091
94RPS6KC10.50025091
95PRKAA20.49786156
96STK30.49733705
97IRAK10.49250184
98MAPKAPK50.48781498
99RIPK40.48389917
100ERBB40.48118293
101LYN0.47958482
102PRKAA10.47721054
103NLK0.47621691
104PLK20.47263601
105CAMK1D0.47062812
106RPS6KA60.46979884
107MARK30.46814601
108CDK120.46134105
109STK40.45766137
110CAMKK10.45061998
111CSNK1A1L0.44793167
112TRPM70.44634290
113TBK10.42579467
114CAMK40.42072939
115BTK0.41397804
116STK110.41130922
117CHEK20.40929612
118MAP2K60.40878826
119EPHA40.40760589
120CSNK1D0.40640472
121RPS6KB10.39807162
122FGFR20.39707813
123ERN10.39500775
124RPS6KA30.39441114
125EPHB20.38459568
126PRKCH0.38006084
127PRKG10.37205906
128PBK0.36783071
129PIM10.36295634
130PRKACA0.35803719
131PRKCB0.35444925
132PLK10.35374204
133ABL10.34533156
134PRKCQ0.34366617
135PLK30.33999112
136PRKCA0.33895527
137CSNK1A10.33692198
138TTK0.33343487
139HCK0.33240323
140EIF2AK30.32998407
141DYRK30.32427118
142OBSCN0.31778754
143SYK0.31636938
144ATM0.31340856
145LATS10.31163417
146DYRK1A0.30915237
147CSNK1G20.30668774
148DYRK20.28845146

Predicted pathways (KEGG)

RankGene SetZ-score
1Fanconi anemia pathway_Homo sapiens_hsa034603.12006551
2Dorso-ventral axis formation_Homo sapiens_hsa043202.34216300
3Graft-versus-host disease_Homo sapiens_hsa053322.26705665
4Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.21805815
5NF-kappa B signaling pathway_Homo sapiens_hsa040642.13194833
6Intestinal immune network for IgA production_Homo sapiens_hsa046722.08211087
7Butanoate metabolism_Homo sapiens_hsa006502.07422549
8Neuroactive ligand-receptor interaction_Homo sapiens_hsa040802.04572101
9Nicotine addiction_Homo sapiens_hsa050332.01378089
10Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.01005888
11Autoimmune thyroid disease_Homo sapiens_hsa053202.00261621
12Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.96771944
13Allograft rejection_Homo sapiens_hsa053301.94906722
14Non-homologous end-joining_Homo sapiens_hsa034501.92876621
15Nitrogen metabolism_Homo sapiens_hsa009101.86724132
16Hematopoietic cell lineage_Homo sapiens_hsa046401.85797212
17Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.84863371
18Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.77651644
19Homologous recombination_Homo sapiens_hsa034401.76508192
20Tryptophan metabolism_Homo sapiens_hsa003801.66839499
21Vitamin digestion and absorption_Homo sapiens_hsa049771.62892180
22Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.62424778
23Asthma_Homo sapiens_hsa053101.56416065
24Rheumatoid arthritis_Homo sapiens_hsa053231.55998154
25Salivary secretion_Homo sapiens_hsa049701.50437192
26Toll-like receptor signaling pathway_Homo sapiens_hsa046201.49809406
27RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.44893996
28Measles_Homo sapiens_hsa051621.44881994
29Arachidonic acid metabolism_Homo sapiens_hsa005901.44319568
30Phototransduction_Homo sapiens_hsa047441.42160114
31Primary immunodeficiency_Homo sapiens_hsa053401.41846553
32Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.38338982
33Primary bile acid biosynthesis_Homo sapiens_hsa001201.37209705
34Taste transduction_Homo sapiens_hsa047421.35791776
35Glycerolipid metabolism_Homo sapiens_hsa005611.32753187
36Morphine addiction_Homo sapiens_hsa050321.30234292
37Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.26980366
38Herpes simplex infection_Homo sapiens_hsa051681.25226380
39NOD-like receptor signaling pathway_Homo sapiens_hsa046211.24227766
40TNF signaling pathway_Homo sapiens_hsa046681.24215893
41Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.24159244
42Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.17360220
43alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.13599713
44Type I diabetes mellitus_Homo sapiens_hsa049401.11416440
45Ovarian steroidogenesis_Homo sapiens_hsa049131.11282872
46Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.10539225
47Malaria_Homo sapiens_hsa051441.08794110
48Linoleic acid metabolism_Homo sapiens_hsa005911.08605125
49ABC transporters_Homo sapiens_hsa020101.07887209
50Jak-STAT signaling pathway_Homo sapiens_hsa046301.07725013
51Vascular smooth muscle contraction_Homo sapiens_hsa042701.07067593
52Sphingolipid metabolism_Homo sapiens_hsa006001.06060562
53Influenza A_Homo sapiens_hsa051641.04991957
54Basal transcription factors_Homo sapiens_hsa030221.04332031
55Steroid hormone biosynthesis_Homo sapiens_hsa001401.03990654
56Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.02554057
57Selenocompound metabolism_Homo sapiens_hsa004501.01216951
58GABAergic synapse_Homo sapiens_hsa047271.00647196
59Leishmaniasis_Homo sapiens_hsa051401.00561124
60One carbon pool by folate_Homo sapiens_hsa006701.00330722
61Olfactory transduction_Homo sapiens_hsa047400.99962535
62Cyanoamino acid metabolism_Homo sapiens_hsa004600.97187869
63Circadian rhythm_Homo sapiens_hsa047100.96802595
64Chemical carcinogenesis_Homo sapiens_hsa052040.95627257
65Ether lipid metabolism_Homo sapiens_hsa005650.92837243
66Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.92164729
67Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.91063560
68SNARE interactions in vesicular transport_Homo sapiens_hsa041300.90332518
69African trypanosomiasis_Homo sapiens_hsa051430.88053798
70Long-term depression_Homo sapiens_hsa047300.87921410
71Caffeine metabolism_Homo sapiens_hsa002320.86245214
72Maturity onset diabetes of the young_Homo sapiens_hsa049500.85775688
73Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.85685685
74Renin secretion_Homo sapiens_hsa049240.85170269
75Oxytocin signaling pathway_Homo sapiens_hsa049210.82915738
76Glycerophospholipid metabolism_Homo sapiens_hsa005640.81408978
77Inositol phosphate metabolism_Homo sapiens_hsa005620.79294017
78Calcium signaling pathway_Homo sapiens_hsa040200.78205054
79Pancreatic secretion_Homo sapiens_hsa049720.78195002
80Transcriptional misregulation in cancer_Homo sapiens_hsa052020.76954245
81Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.76805459
82Other glycan degradation_Homo sapiens_hsa005110.75985018
83Collecting duct acid secretion_Homo sapiens_hsa049660.74302061
84Cholinergic synapse_Homo sapiens_hsa047250.73930458
85Legionellosis_Homo sapiens_hsa051340.73585780
86Phagosome_Homo sapiens_hsa041450.73364814
87Serotonergic synapse_Homo sapiens_hsa047260.72949431
88Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.71633251
89Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.71538039
90Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.70955778
91Chemokine signaling pathway_Homo sapiens_hsa040620.69664987
92Propanoate metabolism_Homo sapiens_hsa006400.69430104
93Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.69274379
94Lysine degradation_Homo sapiens_hsa003100.68409836
95Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.67191480
96Osteoclast differentiation_Homo sapiens_hsa043800.66974404
97Tuberculosis_Homo sapiens_hsa051520.66880668
98Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.66219740
99Mineral absorption_Homo sapiens_hsa049780.64615132
100Peroxisome_Homo sapiens_hsa041460.64525797
101beta-Alanine metabolism_Homo sapiens_hsa004100.64119904
102Gastric acid secretion_Homo sapiens_hsa049710.64046117
103Aldosterone synthesis and secretion_Homo sapiens_hsa049250.64021823
104Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.63747512
105Phosphatidylinositol signaling system_Homo sapiens_hsa040700.63660228
106Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.63606680
107Glycosaminoglycan degradation_Homo sapiens_hsa005310.62381229
108Glutamatergic synapse_Homo sapiens_hsa047240.61099390
109Hepatitis B_Homo sapiens_hsa051610.58880034
110Base excision repair_Homo sapiens_hsa034100.58793360
111p53 signaling pathway_Homo sapiens_hsa041150.57491822
112RNA polymerase_Homo sapiens_hsa030200.57309345
113Retinol metabolism_Homo sapiens_hsa008300.56636262
114Basal cell carcinoma_Homo sapiens_hsa052170.55694617
115Purine metabolism_Homo sapiens_hsa002300.54943410
116Carbohydrate digestion and absorption_Homo sapiens_hsa049730.54694779
117RNA degradation_Homo sapiens_hsa030180.54461862
118Vitamin B6 metabolism_Homo sapiens_hsa007500.52668879
119Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.51823321
120Platelet activation_Homo sapiens_hsa046110.51015811
121Melanoma_Homo sapiens_hsa052180.49647073
122Histidine metabolism_Homo sapiens_hsa003400.49264841
123Amphetamine addiction_Homo sapiens_hsa050310.48821087
124Staphylococcus aureus infection_Homo sapiens_hsa051500.46924798
125Dopaminergic synapse_Homo sapiens_hsa047280.46693902
126Regulation of autophagy_Homo sapiens_hsa041400.45442661
127Circadian entrainment_Homo sapiens_hsa047130.44839741
128cGMP-PKG signaling pathway_Homo sapiens_hsa040220.44012340
129Apoptosis_Homo sapiens_hsa042100.40647648
130Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.40633601
131Fatty acid biosynthesis_Homo sapiens_hsa000610.38274233
132Insulin secretion_Homo sapiens_hsa049110.38129470
133Hepatitis C_Homo sapiens_hsa051600.38123130
134cAMP signaling pathway_Homo sapiens_hsa040240.38071103
135Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.37079960
136Type II diabetes mellitus_Homo sapiens_hsa049300.36910266
137Wnt signaling pathway_Homo sapiens_hsa043100.36393905
138Ras signaling pathway_Homo sapiens_hsa040140.36372785
139Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.35396173
140Pertussis_Homo sapiens_hsa051330.34421846
141Estrogen signaling pathway_Homo sapiens_hsa049150.32205138
142MAPK signaling pathway_Homo sapiens_hsa040100.32194158
143Small cell lung cancer_Homo sapiens_hsa052220.32044564
144Toxoplasmosis_Homo sapiens_hsa051450.31230287
145Axon guidance_Homo sapiens_hsa043600.30672884
146Cocaine addiction_Homo sapiens_hsa050300.29356249
147HTLV-I infection_Homo sapiens_hsa051660.29011985

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