CCDC149

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)6.00813165
2synaptic vesicle maturation (GO:0016188)5.46325628
3synaptic vesicle exocytosis (GO:0016079)5.41321721
4locomotory exploration behavior (GO:0035641)5.34360925
5positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.31120261
6vocalization behavior (GO:0071625)5.05948503
7regulation of synaptic vesicle exocytosis (GO:2000300)5.00326125
8positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.91271819
9synaptic vesicle docking involved in exocytosis (GO:0016081)4.88403056
10glutamate secretion (GO:0014047)4.84670302
11regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.70116049
12regulation of synaptic vesicle transport (GO:1902803)4.58249141
13regulation of glutamate receptor signaling pathway (GO:1900449)4.48612901
14ionotropic glutamate receptor signaling pathway (GO:0035235)4.48586861
15neurotransmitter secretion (GO:0007269)4.30292673
16regulation of long-term neuronal synaptic plasticity (GO:0048169)4.28164568
17neuronal action potential propagation (GO:0019227)4.28062395
18exploration behavior (GO:0035640)4.26218113
19regulation of neuronal synaptic plasticity (GO:0048168)4.23494733
20protein localization to synapse (GO:0035418)4.16435892
21regulation of synapse structural plasticity (GO:0051823)4.16339958
22synaptic transmission, glutamatergic (GO:0035249)4.08275715
23neuron cell-cell adhesion (GO:0007158)3.96553350
24regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.89823757
25neuron-neuron synaptic transmission (GO:0007270)3.89631174
26glutamate receptor signaling pathway (GO:0007215)3.88574022
27layer formation in cerebral cortex (GO:0021819)3.76800136
28long-term memory (GO:0007616)3.73491531
29proline transport (GO:0015824)3.72115487
30activation of protein kinase A activity (GO:0034199)3.68176519
31membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.64973200
32cellular potassium ion homeostasis (GO:0030007)3.55720165
33regulation of excitatory postsynaptic membrane potential (GO:0060079)3.52936709
34neurotransmitter transport (GO:0006836)3.51992520
35neuron recognition (GO:0008038)3.43561285
36gamma-aminobutyric acid transport (GO:0015812)3.40818303
37positive regulation of membrane potential (GO:0045838)3.40220493
38regulation of synaptic plasticity (GO:0048167)3.39660495
39regulation of postsynaptic membrane potential (GO:0060078)3.39446760
40neurotransmitter-gated ion channel clustering (GO:0072578)3.36927227
41cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.35298997
42long-term synaptic potentiation (GO:0060291)3.35275010
43dendritic spine morphogenesis (GO:0060997)3.34460760
44gamma-aminobutyric acid signaling pathway (GO:0007214)3.31817062
45transmission of nerve impulse (GO:0019226)3.30454169
46regulation of neurotransmitter secretion (GO:0046928)3.30041456
47regulation of neurotransmitter levels (GO:0001505)3.27832079
48regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.27446775
49regulation of vesicle fusion (GO:0031338)3.27423978
50positive regulation of synaptic transmission, GABAergic (GO:0032230)3.27317723
51positive regulation of synapse maturation (GO:0090129)3.26911739
52synaptic vesicle endocytosis (GO:0048488)3.20168265
53sodium ion export (GO:0071436)3.19988423
54negative regulation of synaptic transmission, GABAergic (GO:0032229)3.15732460
55negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.12964838
56regulation of dendritic spine morphogenesis (GO:0061001)3.12297427
57G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.11799470
58neuromuscular process controlling posture (GO:0050884)3.11684355
59cell communication by electrical coupling (GO:0010644)3.10415128
60regulation of synaptic transmission, glutamatergic (GO:0051966)3.09113112
61regulation of neurotransmitter transport (GO:0051588)3.06263862
62positive regulation of neurotransmitter secretion (GO:0001956)3.06075147
63positive regulation of neurotransmitter transport (GO:0051590)3.04875648
64neuronal ion channel clustering (GO:0045161)3.02717835
65positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.02175285
66behavioral fear response (GO:0001662)3.01463058
67behavioral defense response (GO:0002209)3.01463058
68vesicle transport along microtubule (GO:0047496)3.01450971
69neuromuscular process controlling balance (GO:0050885)3.01189583
70positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.99943273
71striatum development (GO:0021756)2.98779351
72membrane depolarization during action potential (GO:0086010)2.98096430
73axonal fasciculation (GO:0007413)2.97889029
74cerebellar Purkinje cell differentiation (GO:0021702)2.97424568
75innervation (GO:0060384)2.97021430
76postsynaptic membrane organization (GO:0001941)2.96572066
77glycine transport (GO:0015816)2.94000451
78detection of calcium ion (GO:0005513)2.93940199
79membrane depolarization (GO:0051899)2.92715848
80fear response (GO:0042596)2.92265491
81prepulse inhibition (GO:0060134)2.91933327
82regulation of glutamate secretion (GO:0014048)2.90382349
83chemosensory behavior (GO:0007635)2.88223593
84regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.88083073
85positive regulation of synaptic transmission (GO:0050806)2.88005649
86learning (GO:0007612)2.87326456
87membrane hyperpolarization (GO:0060081)2.86518538
88regulation of synaptic transmission (GO:0050804)2.86111636
89response to histamine (GO:0034776)2.85077696
90auditory behavior (GO:0031223)2.84692744
91behavioral response to cocaine (GO:0048148)2.84606268
92negative regulation of cytosolic calcium ion concentration (GO:0051481)2.83811716
93regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.83026288
94synaptic transmission (GO:0007268)2.82778712
95response to auditory stimulus (GO:0010996)2.81537892
96dendrite morphogenesis (GO:0048813)2.81299880
97dendritic spine organization (GO:0097061)2.80957805
98regulation of calcium ion-dependent exocytosis (GO:0017158)2.79845231
99regulation of voltage-gated calcium channel activity (GO:1901385)2.79274410
100regulation of ARF protein signal transduction (GO:0032012)2.78247318
101positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.77902725
102cell wall macromolecule catabolic process (GO:0016998)2.77842352
103urinary tract smooth muscle contraction (GO:0014848)2.66576800
104macroautophagy (GO:0016236)2.57450536
105regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.47500941
106positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.40398039
107calcium ion-dependent exocytosis (GO:0017156)2.35773081
108cell wall macromolecule metabolic process (GO:0044036)2.35161564
109behavioral response to ethanol (GO:0048149)2.31068459
110cellular response to ATP (GO:0071318)2.23136842
111axoneme assembly (GO:0035082)2.21874315
112startle response (GO:0001964)2.20876769
113central nervous system myelination (GO:0022010)2.19656353
114axon ensheathment in central nervous system (GO:0032291)2.19656353
115glycosphingolipid biosynthetic process (GO:0006688)2.19490047
116presynaptic membrane organization (GO:0097090)2.19239426
117adaptation of signaling pathway (GO:0023058)2.17814819
118negative regulation of mast cell activation (GO:0033004)2.16144736
119regulation of type B pancreatic cell apoptotic process (GO:2000674)2.14114185
120negative regulation of cAMP-mediated signaling (GO:0043951)2.10272984
121alanine transport (GO:0032328)2.09330684
122retinal cone cell development (GO:0046549)2.04927516
123presynaptic membrane assembly (GO:0097105)2.04160675
124serotonin metabolic process (GO:0042428)2.03775805
125cyclic nucleotide catabolic process (GO:0009214)2.02242819
126sphingoid metabolic process (GO:0046519)2.01924060
127smooth muscle tissue development (GO:0048745)2.01259013
128cellular potassium ion transport (GO:0071804)2.00480989
129potassium ion transmembrane transport (GO:0071805)2.00480989
130neuronal action potential (GO:0019228)1.99655464
131regulation of clathrin-mediated endocytosis (GO:2000369)1.97721888
132nucleobase catabolic process (GO:0046113)1.97561504
133regulation of female receptivity (GO:0045924)1.97368685
134potassium ion transport (GO:0006813)1.93879669
135G-protein coupled glutamate receptor signaling pathway (GO:0007216)1.93277098
136relaxation of cardiac muscle (GO:0055119)1.92178699
137growth hormone receptor signaling pathway (GO:0060396)1.91974081
138regulation of neurotransmitter uptake (GO:0051580)1.91564162
139behavioral response to nicotine (GO:0035095)1.91463849
140righting reflex (GO:0060013)1.89851987
141primary amino compound metabolic process (GO:1901160)1.88221950
142reflex (GO:0060004)1.87540851
143Golgi to endosome transport (GO:0006895)1.86806726
144cAMP catabolic process (GO:0006198)1.86506957
145central nervous system neuron axonogenesis (GO:0021955)1.86084830
146photoreceptor cell maintenance (GO:0045494)1.84543903
147regulation of acrosome reaction (GO:0060046)1.83834530
148inner ear receptor stereocilium organization (GO:0060122)1.83493401
149regulation of dendritic spine development (GO:0060998)1.83441561
150cardiac conduction (GO:0061337)1.82956710
151insulin secretion (GO:0030073)1.82193133
152prostate gland growth (GO:0060736)1.80261058
153membrane repolarization during cardiac muscle cell action potential (GO:0086013)1.79597990
154chondroitin sulfate catabolic process (GO:0030207)1.79597796
155positive regulation of meiosis (GO:0045836)1.79038871
156pyrimidine nucleobase catabolic process (GO:0006208)1.77923387

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.84241966
2GBX2_23144817_ChIP-Seq_PC3_Human3.33855316
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.05626410
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.02003015
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.91298674
6RNF2_18974828_ChIP-Seq_MESCs_Mouse2.65388938
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.65388938
8JARID2_20075857_ChIP-Seq_MESCs_Mouse2.65074090
9REST_21632747_ChIP-Seq_MESCs_Mouse2.63906895
10SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.60714877
11SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.58282333
12RARB_27405468_Chip-Seq_BRAIN_Mouse2.57517248
13MTF2_20144788_ChIP-Seq_MESCs_Mouse2.54335291
14DROSHA_22980978_ChIP-Seq_HELA_Human2.49664912
15SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.47469239
16SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.43512465
17EZH2_27304074_Chip-Seq_ESCs_Mouse2.35628187
18SUZ12_27294783_Chip-Seq_ESCs_Mouse2.23986738
19EZH2_27294783_Chip-Seq_ESCs_Mouse2.21929266
20EED_16625203_ChIP-ChIP_MESCs_Mouse2.20607002
21REST_18959480_ChIP-ChIP_MESCs_Mouse2.15239251
22RNF2_27304074_Chip-Seq_ESCs_Mouse2.10395862
23IKZF1_21737484_ChIP-ChIP_HCT116_Human1.96257508
24MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.85122235
25CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.82680277
26CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.81813711
27NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.78631745
28TAF15_26573619_Chip-Seq_HEK293_Human1.77071667
29ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.76982430
30GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.70426543
31CTBP2_25329375_ChIP-Seq_LNCAP_Human1.69513865
32EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.66312785
33* SMAD4_21799915_ChIP-Seq_A2780_Human1.59731487
34ERG_21242973_ChIP-ChIP_JURKAT_Human1.59082908
35AR_21572438_ChIP-Seq_LNCaP_Human1.58938615
36CTBP1_25329375_ChIP-Seq_LNCAP_Human1.56979681
37ZNF274_21170338_ChIP-Seq_K562_Hela1.55527960
38TP53_16413492_ChIP-PET_HCT116_Human1.51150581
39SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.49841918
40VDR_22108803_ChIP-Seq_LS180_Human1.41568379
41NR3C1_23031785_ChIP-Seq_PC12_Mouse1.39692322
42TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.37781770
43PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.34727769
44AR_25329375_ChIP-Seq_VCAP_Human1.32518574
45CJUN_26792858_Chip-Seq_BT549_Human1.32064140
46ESR1_21235772_ChIP-Seq_MCF-7_Human1.30684591
47SMAD_19615063_ChIP-ChIP_OVARY_Human1.29458600
48SOX2_21211035_ChIP-Seq_LN229_Gbm1.29444347
49ESR2_21235772_ChIP-Seq_MCF-7_Human1.28881778
50RING1B_27294783_Chip-Seq_ESCs_Mouse1.28150059
51NRF2_20460467_ChIP-Seq_MEFs_Mouse1.27588517
52NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.27588517
53SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.27351624
54* P300_19829295_ChIP-Seq_ESCs_Human1.27216329
55CDX2_19796622_ChIP-Seq_MESCs_Mouse1.24966811
56DNAJC2_21179169_ChIP-ChIP_NT2_Human1.24299489
57TOP2B_26459242_ChIP-Seq_MCF-7_Human1.22494418
58BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.20398642
59ZFP57_27257070_Chip-Seq_ESCs_Mouse1.20145858
60RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.19552081
61ZNF217_24962896_ChIP-Seq_MCF-7_Human1.19518063
62PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.19469678
63TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.18742021
64POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.18742021
65* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.17994102
66SMAD3_21741376_ChIP-Seq_EPCs_Human1.17913158
67ER_23166858_ChIP-Seq_MCF-7_Human1.17879938
68IGF1R_20145208_ChIP-Seq_DFB_Human1.17144227
69STAT3_23295773_ChIP-Seq_U87_Human1.16647596
70AR_19668381_ChIP-Seq_PC3_Human1.15296449
71TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.15172854
72ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.14695300
73OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.14209679
74TRIM28_21343339_ChIP-Seq_HEK293_Human1.14154682
75PIAS1_25552417_ChIP-Seq_VCAP_Human1.14012180
76EP300_21415370_ChIP-Seq_HL-1_Mouse1.13796313
77PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.12872616
78AHR_22903824_ChIP-Seq_MCF-7_Human1.11311841
79GATA2_21666600_ChIP-Seq_HMVEC_Human1.10811407
80TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10600989
81BMI1_23680149_ChIP-Seq_NPCS_Mouse1.10306988
82ARNT_22903824_ChIP-Seq_MCF-7_Human1.10259650
83ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.10201392
84RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.08191580
85TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.08117404
86GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06146562
87MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.05571593
88SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.05244793
89WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.04525770
90* TCF4_23295773_ChIP-Seq_U87_Human1.04062952
91P53_22127205_ChIP-Seq_FIBROBLAST_Human1.03556039
92RING1B_27294783_Chip-Seq_NPCs_Mouse1.02962056
93KDM2B_26808549_Chip-Seq_K562_Human1.02939966
94POU3F2_20337985_ChIP-ChIP_501MEL_Human1.01123907
95RXR_22108803_ChIP-Seq_LS180_Human1.00988957
96CBX2_27304074_Chip-Seq_ESCs_Mouse1.00966850
97TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.00963877
98EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.00506452
99SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.99440288
100AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.98688100
101YAP1_20516196_ChIP-Seq_MESCs_Mouse0.98507897
102KDM2B_26808549_Chip-Seq_REH_Human0.98043763
103TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.97957476
104NR3C1_21868756_ChIP-Seq_MCF10A_Human0.97704950
105EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.96964037
106CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.96894765
107FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.96739123
108NANOG_18555785_Chip-Seq_ESCs_Mouse0.95734026
109MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.95554919
110IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.94985285
111CBP_20019798_ChIP-Seq_JUKART_Human0.94985285
112GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.93996645
113SMAD3_21741376_ChIP-Seq_ESCs_Human0.93435975
114* PRDM14_20953172_ChIP-Seq_ESCs_Human0.92689403
115RUNX2_22187159_ChIP-Seq_PCA_Human0.92572709
116SMAD3_21741376_ChIP-Seq_HESCs_Human0.92003803
117SMAD4_21741376_ChIP-Seq_HESCs_Human0.91188614
118CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.91141226
119ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.89386110
120ZFP281_18757296_ChIP-ChIP_E14_Mouse0.88213180
121BCAT_22108803_ChIP-Seq_LS180_Human0.87869007
122RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.86494796
123RNF2_27304074_Chip-Seq_NSC_Mouse0.86187510
124ESR1_20079471_ChIP-ChIP_T-47D_Human0.86181353
125TET1_21490601_ChIP-Seq_MESCs_Mouse0.85996930
126* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.85810071
127TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.84464051
128JUN_21703547_ChIP-Seq_K562_Human0.82285320
129TP53_18474530_ChIP-ChIP_U2OS_Human0.80328584

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.23123441
2MP0003880_abnormal_central_pattern4.66869290
3MP0003635_abnormal_synaptic_transmissio4.02903040
4MP0004270_analgesia3.59876684
5MP0009745_abnormal_behavioral_response3.32973351
6MP0002063_abnormal_learning/memory/cond3.26639178
7MP0002064_seizures3.02401283
8MP0001968_abnormal_touch/_nociception2.90890055
9MP0002822_catalepsy2.86787119
10MP0009046_muscle_twitch2.71869519
11MP0002572_abnormal_emotion/affect_behav2.68640856
12MP0000569_abnormal_digit_pigmentation2.67318603
13MP0002272_abnormal_nervous_system2.57041673
14MP0002734_abnormal_mechanical_nocicepti2.49852284
15MP0005423_abnormal_somatic_nervous2.48824156
16MP0001501_abnormal_sleep_pattern2.48643136
17MP0002736_abnormal_nociception_after2.29855673
18MP0001486_abnormal_startle_reflex2.24425479
19MP0009780_abnormal_chondrocyte_physiolo2.22393401
20MP0002735_abnormal_chemical_nociception2.21332110
21MP0002909_abnormal_adrenal_gland2.12473491
22MP0005503_abnormal_tendon_morphology2.07562830
23MP0001440_abnormal_grooming_behavior2.01043807
24MP0003172_abnormal_lysosome_physiology1.95559594
25MP0001970_abnormal_pain_threshold1.93554254
26MP0002733_abnormal_thermal_nociception1.92381710
27MP0005646_abnormal_pituitary_gland1.91095019
28MP0002067_abnormal_sensory_capabilities1.88612120
29MP0003329_amyloid_beta_deposits1.87912205
30MP0001984_abnormal_olfaction1.77638784
31MP0003195_calcinosis1.77557168
32MP0008569_lethality_at_weaning1.72672816
33MP0002557_abnormal_social/conspecific_i1.69728553
34MP0003787_abnormal_imprinting1.69046534
35MP0006276_abnormal_autonomic_nervous1.64600227
36MP0002184_abnormal_innervation1.63490301
37MP0004811_abnormal_neuron_physiology1.62605225
38MP0004858_abnormal_nervous_system1.59927424
39MP0001958_emphysema1.59009497
40MP0003283_abnormal_digestive_organ1.58330412
41MP0004924_abnormal_behavior1.55055550
42MP0005386_behavior/neurological_phenoty1.55055550
43MP0005645_abnormal_hypothalamus_physiol1.54119945
44MP0000955_abnormal_spinal_cord1.51620458
45MP0000778_abnormal_nervous_system1.47634698
46MP0003879_abnormal_hair_cell1.46879346
47MP0004885_abnormal_endolymph1.40876734
48MP0008438_abnormal_cutaneous_collagen1.40630265
49MP0003122_maternal_imprinting1.40327161
50MP0000427_abnormal_hair_cycle1.39318844
51MP0010386_abnormal_urinary_bladder1.35782012
52MP0000013_abnormal_adipose_tissue1.35158297
53MP0002066_abnormal_motor_capabilities/c1.34872054
54MP0002882_abnormal_neuron_morphology1.32908794
55MP0003633_abnormal_nervous_system1.31472575
56MP0003045_fibrosis1.30583087
57MP0002837_dystrophic_cardiac_calcinosis1.29662401
58MP0001502_abnormal_circadian_rhythm1.24410978
59MP0005595_abnormal_vascular_smooth1.18250130
60MP0004142_abnormal_muscle_tone1.15328756
61MP0006054_spinal_hemorrhage1.14360811
62MP0002876_abnormal_thyroid_physiology1.14228863
63MP0005394_taste/olfaction_phenotype1.13267965
64MP0005499_abnormal_olfactory_system1.13267965
65MP0005275_abnormal_skin_tensile1.12823831
66MP0001542_abnormal_bone_strength1.12401830
67MP0001905_abnormal_dopamine_level1.11233303
68MP0000383_abnormal_hair_follicle1.10287163
69MP0002168_other_aberrant_phenotype1.10072790
70MP0005535_abnormal_body_temperature1.08840761
71MP0001188_hyperpigmentation1.08269446
72MP0003631_nervous_system_phenotype1.05991365
73MP0000751_myopathy1.04819501
74MP0002295_abnormal_pulmonary_circulatio1.03542788
75MP0001529_abnormal_vocalization1.03369215
76MP0003191_abnormal_cellular_cholesterol0.99981928
77MP0008872_abnormal_physiological_respon0.99302308
78MP0010678_abnormal_skin_adnexa0.97712357
79MP0002069_abnormal_eating/drinking_beha0.97277954
80MP0010234_abnormal_vibrissa_follicle0.97081385
81MP0002229_neurodegeneration0.96740728
82MP0000230_abnormal_systemic_arterial0.94288810
83MP0003724_increased_susceptibility_to0.94213652
84MP0008874_decreased_physiological_sensi0.93734397
85MP0008961_abnormal_basal_metabolism0.93508345
86MP0002152_abnormal_brain_morphology0.93441319
87MP0004085_abnormal_heartbeat0.93178246
88MP0001664_abnormal_digestion0.90943760
89MP0000015_abnormal_ear_pigmentation0.90670060
90MP0003137_abnormal_impulse_conducting0.90454238
91MP0004510_myositis0.90029597
92MP0004145_abnormal_muscle_electrophysio0.89209272
93MP0001177_atelectasis0.88703022
94MP0004043_abnormal_pH_regulation0.85349718
95MP0001756_abnormal_urination0.84898281
96MP0002896_abnormal_bone_mineralization0.83190770
97MP0003075_altered_response_to0.82735599
98MP0003279_aneurysm0.82588962
99MP0005409_darkened_coat_color0.81662110
100MP0005551_abnormal_eye_electrophysiolog0.80490570
101MP0005508_abnormal_skeleton_morphology0.80235177
102MP0000631_abnormal_neuroendocrine_gland0.80158645
103MP0002234_abnormal_pharynx_morphology0.79863492
104MP0001986_abnormal_taste_sensitivity0.79622517
105MP0002108_abnormal_muscle_morphology0.78720847
106MP0008875_abnormal_xenobiotic_pharmacok0.78276525
107MP0003646_muscle_fatigue0.78093875
108MP0000604_amyloidosis0.77764480
109MP0005058_abnormal_lysosome_morphology0.77308564
110MP0005164_abnormal_response_to0.76102598
111MP0000538_abnormal_urinary_bladder0.75753122
112MP0009384_cardiac_valve_regurgitation0.75492059
113MP0001765_abnormal_ion_homeostasis0.75041524
114MP0004742_abnormal_vestibular_system0.72061685
115MP0003634_abnormal_glial_cell0.71697436
116MP0005174_abnormal_tail_pigmentation0.71536919
117MP0005187_abnormal_penis_morphology0.70308966
118MP0003632_abnormal_nervous_system0.70143875
119MP0001963_abnormal_hearing_physiology0.69791436
120MP0002693_abnormal_pancreas_physiology0.69559181
121MP0003690_abnormal_glial_cell0.67770670
122MP0004215_abnormal_myocardial_fiber0.67423187
123MP0008004_abnormal_stomach_pH0.65381016
124MP0005167_abnormal_blood-brain_barrier0.64815615
125MP0004484_altered_response_of0.64701244
126MP0002752_abnormal_somatic_nervous0.62748846
127MP0002090_abnormal_vision0.61788376
128MP0003183_abnormal_peptide_metabolism0.61265278
129MP0001299_abnormal_eye_distance/0.61198526
130MP0001485_abnormal_pinna_reflex0.58621507
131MP0000003_abnormal_adipose_tissue0.57214495
132MP0000920_abnormal_myelination0.56854996
133MP0004130_abnormal_muscle_cell0.55613369
134MP0001944_abnormal_pancreas_morphology0.55547146
135MP0005623_abnormal_meninges_morphology0.53659292
136MP0000534_abnormal_ureter_morphology0.53278812

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.82203436
2Myokymia (HP:0002411)6.81275555
3Visual hallucinations (HP:0002367)5.51643454
4Focal seizures (HP:0007359)5.47769282
5Atonic seizures (HP:0010819)4.62142656
6Febrile seizures (HP:0002373)4.47756575
7Epileptic encephalopathy (HP:0200134)4.47228651
8Absence seizures (HP:0002121)4.18802141
9Supranuclear gaze palsy (HP:0000605)3.78226944
10Progressive cerebellar ataxia (HP:0002073)3.77447131
11Dialeptic seizures (HP:0011146)3.76611305
12Generalized tonic-clonic seizures (HP:0002069)3.74872455
13Action tremor (HP:0002345)3.68255418
14Hyperventilation (HP:0002883)3.45280498
15Ankle clonus (HP:0011448)3.42616338
16Depression (HP:0000716)3.35695156
17Anxiety (HP:0000739)3.35043712
18Abnormality of glycolipid metabolism (HP:0010969)3.17906694
19Abnormality of liposaccharide metabolism (HP:0010968)3.17906694
20Abnormality of glycosphingolipid metabolism (HP:0004343)3.17906694
21Papilledema (HP:0001085)3.13422829
22Impaired vibration sensation in the lower limbs (HP:0002166)3.12583160
23Amblyopia (HP:0000646)3.08959608
24Poor eye contact (HP:0000817)3.08129630
25Broad-based gait (HP:0002136)3.01759042
26Thyroid-stimulating hormone excess (HP:0002925)2.93779850
27Impaired social interactions (HP:0000735)2.89247379
28Abnormal social behavior (HP:0012433)2.89247379
29Progressive inability to walk (HP:0002505)2.88064137
30Abnormality of mucopolysaccharide metabolism (HP:0011020)2.84586768
31Abnormality of polysaccharide metabolism (HP:0011012)2.84586768
32Abnormality of glycosaminoglycan metabolism (HP:0004371)2.84586768
33Truncal ataxia (HP:0002078)2.79859245
34Dysmetria (HP:0001310)2.78252625
35Abnormal eating behavior (HP:0100738)2.72320946
36Dysdiadochokinesis (HP:0002075)2.70489084
37Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.70345471
38Gaze-evoked nystagmus (HP:0000640)2.67606257
39Urinary bladder sphincter dysfunction (HP:0002839)2.66836468
40Postural instability (HP:0002172)2.65339682
41Torticollis (HP:0000473)2.64907472
42Mucopolysacchariduria (HP:0008155)2.64027088
43Urinary glycosaminoglycan excretion (HP:0003541)2.64027088
44Epileptiform EEG discharges (HP:0011182)2.59568592
45Cerebral inclusion bodies (HP:0100314)2.58692329
46Ventricular fibrillation (HP:0001663)2.58446559
47Pheochromocytoma (HP:0002666)2.56919443
48EEG with generalized epileptiform discharges (HP:0011198)2.51216510
49Agitation (HP:0000713)2.50404101
50Hematochezia (HP:0002573)2.50266179
51Mutism (HP:0002300)2.48828738
52Focal dystonia (HP:0004373)2.47034314
53Increased corneal curvature (HP:0100692)2.45656598
54Keratoconus (HP:0000563)2.45656598
55Bradykinesia (HP:0002067)2.44192845
56Neurofibrillary tangles (HP:0002185)2.41735604
57Drooling (HP:0002307)2.40413740
58Excessive salivation (HP:0003781)2.40413740
59Dysostosis multiplex (HP:0000943)2.40318297
60Urinary urgency (HP:0000012)2.40129125
61Hypsarrhythmia (HP:0002521)2.39397941
62Increased cerebral lipofuscin (HP:0011813)2.36759099
63Hemiparesis (HP:0001269)2.35088547
64Impaired smooth pursuit (HP:0007772)2.32591812
65Widely spaced teeth (HP:0000687)2.29689767
66Craniofacial dystonia (HP:0012179)2.26329147
67Spastic gait (HP:0002064)2.25735210
68True hermaphroditism (HP:0010459)2.23578440
69Chronic hepatic failure (HP:0100626)2.23393984
70Termporal pattern (HP:0011008)2.21366121
71Insidious onset (HP:0003587)2.21366121
72Limb dystonia (HP:0002451)2.21097690
73Megalencephaly (HP:0001355)2.20633509
74Clumsiness (HP:0002312)2.20287252
75Increased neuronal autofluorescent lipopigment (HP:0002074)2.19691973
76Hypoventilation (HP:0002791)2.19669282
77Annular pancreas (HP:0001734)2.19034720
78Abnormality of the lower motor neuron (HP:0002366)2.18211330
79Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.17983811
80Pancreatic fibrosis (HP:0100732)2.17662259
81Stereotypic behavior (HP:0000733)2.17564312
82Diplopia (HP:0000651)2.17495493
83Abnormality of binocular vision (HP:0011514)2.17495493
84Abnormality of the corticospinal tract (HP:0002492)2.17256076
85Failure to thrive in infancy (HP:0001531)2.15572266
86Ankyloglossia (HP:0010296)2.14985602
87Intention tremor (HP:0002080)2.14824174
88Status epilepticus (HP:0002133)2.13278825
89Insomnia (HP:0100785)2.13121235
90Hemiplegia (HP:0002301)2.12828843
91Syncope (HP:0001279)2.12648538
92Neuroendocrine neoplasm (HP:0100634)2.11734925
93Abnormal drinking behavior (HP:0030082)2.11498734
94Polydipsia (HP:0001959)2.11498734
95Scanning speech (HP:0002168)2.10413128
96Decreased circulating renin level (HP:0003351)2.07730711
97Broad metatarsal (HP:0001783)2.07634075
98Pancreatic cysts (HP:0001737)2.07457381
99Abnormality of the renal medulla (HP:0100957)2.06667917
100Bundle branch block (HP:0011710)2.04618003
101Psychosis (HP:0000709)2.04024345
102Nephronophthisis (HP:0000090)2.03907197
103Generalized hypopigmentation of hair (HP:0011358)2.01792025
104Nuclear cataract (HP:0100018)2.00962928
105Hypoplastic ischia (HP:0003175)1.99309144
106Inability to walk (HP:0002540)1.98057881
107Lower limb muscle weakness (HP:0007340)1.97797669
108Absent speech (HP:0001344)1.97386936
109Neoplasm of the peripheral nervous system (HP:0100007)1.96563654
110Type II lissencephaly (HP:0007260)1.95686794
111Retinal dysplasia (HP:0007973)1.94754455
112Hypoplasia of the odontoid process (HP:0003311)1.93947889
113Impaired vibratory sensation (HP:0002495)1.93587293
114Congenital stationary night blindness (HP:0007642)1.92393730
115Blue irides (HP:0000635)1.92168968
116Cardiovascular calcification (HP:0011915)1.92151701
117Choroideremia (HP:0001139)1.92014323
118Abnormality of ocular smooth pursuit (HP:0000617)1.90611735
119Congenital sensorineural hearing impairment (HP:0008527)1.90423782
120Disproportionate short-trunk short stature (HP:0003521)1.90183516
121Bradycardia (HP:0001662)1.90018978
122Genetic anticipation (HP:0003743)1.89885987
123Clonus (HP:0002169)1.89668366
124Vascular tortuosity (HP:0004948)1.89001376
125Amelogenesis imperfecta (HP:0000705)1.88601717
126Vacuolated lymphocytes (HP:0001922)1.87554023
127Aortic dissection (HP:0002647)1.87523139
128Generalized myoclonic seizures (HP:0002123)1.86271640
129Protruding tongue (HP:0010808)1.85956343
130Rapidly progressive (HP:0003678)1.84935983
131Abnormal EKG (HP:0003115)1.84880586
132Delusions (HP:0000746)1.84740608
133Hypercortisolism (HP:0001578)1.84727191
134Degeneration of the lateral corticospinal tracts (HP:0002314)1.83687017
135Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.83687017
136Vascular calcification (HP:0004934)1.81822045
137Arterial tortuosity (HP:0005116)1.81791786
138Polyphagia (HP:0002591)1.81461552
139Prolonged QT interval (HP:0001657)1.80594708
140Fetal akinesia sequence (HP:0001989)1.79979336
141Gait ataxia (HP:0002066)1.78805190
142Abnormality of the ischium (HP:0003174)1.78596208
143Incomplete penetrance (HP:0003829)1.77937687
144Medial flaring of the eyebrow (HP:0010747)1.77603952
145Impaired pain sensation (HP:0007328)1.77163284
146Abnormality of pain sensation (HP:0010832)1.77163284
147Rigidity (HP:0002063)1.76690828
148Cystic liver disease (HP:0006706)1.75858119
149Obstructive sleep apnea (HP:0002870)1.75548416
150Tubulointerstitial nephritis (HP:0001970)1.75032200
151Large for gestational age (HP:0001520)1.72265027
152Buphthalmos (HP:0000557)1.71625402
153Abnormality of midbrain morphology (HP:0002418)1.71004388
154Molar tooth sign on MRI (HP:0002419)1.71004388
155Gait imbalance (HP:0002141)1.70903026
156Hypothermia (HP:0002045)1.67276607
157Fair hair (HP:0002286)1.66247861
158Mitral stenosis (HP:0001718)1.66032746
159Tubular atrophy (HP:0000092)1.64505615
160Amyloidosis (HP:0011034)1.64428311

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK5.25644652
2NTRK34.54634268
3EPHA44.11139408
4MAP3K93.48963748
5MAP3K42.85956753
6MINK12.69266081
7MAP2K72.55160731
8MAP3K122.49268645
9DAPK22.41868606
10ADRBK22.33772912
11MARK12.33320468
12RIPK42.20014629
13KSR22.17663882
14CAMKK12.15729689
15MAP2K42.11794308
16PAK62.01224633
17PRKD31.99547550
18WNK31.95960989
19NTRK11.94949173
20NTRK21.67754735
21TRPM71.64096626
22MAP3K21.60289677
23STK391.58246572
24DAPK11.57817349
25CDK51.56692146
26CASK1.54841032
27MAPKAPK31.50910680
28GRK51.50539813
29PRKD21.40448813
30CDK191.38749831
31ARAF1.36354541
32CAMKK21.34718322
33PNCK1.32219006
34PLK21.26408276
35UHMK11.25512935
36NME11.23350984
37KSR11.23299318
38GRK11.21979436
39STK381.21612987
40LMTK21.15459125
41SIK21.15247023
42PRKCG1.11183978
43MAP4K21.11100428
44RET1.08498168
45MAP3K131.08290972
46FES1.05243892
47MYLK1.03625466
48PRPF4B1.03447767
49MAPK131.03313572
50RIPK11.03158934
51PHKG21.02583851
52PHKG11.02583851
53CAMK2A1.02059801
54CAMK10.97988232
55BMPR20.97631181
56PINK10.97592161
57MAP3K10.96382866
58TNIK0.95060863
59BMPR1B0.91358424
60LIMK10.90525499
61PRKCH0.89845352
62ADRBK10.88741336
63FGFR20.88388406
64PKN10.86499212
65SGK2230.86411348
66SGK4940.86411348
67CAMK2B0.85318986
68TYRO30.84715500
69TAOK10.84357709
70PAK30.84238878
71TNK20.84008530
72PTK2B0.81923681
73EPHA30.81013728
74PIK3CA0.79318160
75LATS10.79082160
76OXSR10.78211413
77STK110.77537307
78DYRK1A0.74874257
79SCYL20.74645611
80ROCK10.72418264
81LATS20.70313576
82SGK20.70056826
83EPHB10.69941688
84MAPK70.69491136
85CDK180.68574267
86PDPK10.68317262
87CDK150.67990366
88SGK30.66671077
89CDK140.66635269
90IRAK10.66276682
91RAF10.65456094
92STK38L0.65445983
93SGK10.64606516
94DDR20.64415642
95MAPK120.64230672
96PDK10.64077676
97AKT30.63709084
98FER0.63613896
99RPS6KA20.62948402
100PRKCE0.62428079
101MAP2K10.60793026
102TGFBR20.60628582
103INSRR0.59447602
104CAMK1D0.59237694
105MARK20.58943385
106CDK11A0.58458906
107CAMK2D0.57981830
108NUAK10.56747346
109MAP3K60.55693108
110MAP3K70.54864328
111ERBB20.52388688
112CAMK1G0.51928066
113PRKAA20.51614743
114PRKD10.50240199
115CHUK0.49456364
116MAP3K30.49189934
117CSNK1G20.48785666
118PDGFRB0.48605534
119PTK20.48148956
120CAMK2G0.47222211
121SIK30.47032178
122MAPKAPK50.46860162
123GRK70.46827261
124PRKCZ0.46400349
125CDC42BPA0.46242672
126RPS6KA30.45122073
127PRKAA10.43698572
128ALK0.42722919
129ABL10.42689333
130JAK10.41583790
131WNK40.41494871
132EPHB20.41316584
133WNK10.40407313
134FYN0.40401385
135TRIB30.40329680
136PDGFRA0.38272092
137DMPK0.38175792
138MAPK100.37925722
139FGR0.35066020
140MUSK0.34670494
141MAP2K60.33991123
142ROCK20.33829779

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.39403029
2Synaptic vesicle cycle_Homo sapiens_hsa047213.21945051
3GABAergic synapse_Homo sapiens_hsa047272.63970783
4Olfactory transduction_Homo sapiens_hsa047402.61726242
5Circadian entrainment_Homo sapiens_hsa047132.59573480
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.58309848
7Long-term potentiation_Homo sapiens_hsa047202.56593494
8Glutamatergic synapse_Homo sapiens_hsa047242.42363330
9Amphetamine addiction_Homo sapiens_hsa050312.40785792
10Morphine addiction_Homo sapiens_hsa050322.38890263
11Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.26128203
12Insulin secretion_Homo sapiens_hsa049112.20435743
13Dopaminergic synapse_Homo sapiens_hsa047282.13899631
14Salivary secretion_Homo sapiens_hsa049702.10570786
15Gastric acid secretion_Homo sapiens_hsa049711.87083165
16Cholinergic synapse_Homo sapiens_hsa047251.83540493
17Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.82299787
18Taste transduction_Homo sapiens_hsa047421.79258680
19Aldosterone synthesis and secretion_Homo sapiens_hsa049251.77889050
20Renin secretion_Homo sapiens_hsa049241.72165578
21Cocaine addiction_Homo sapiens_hsa050301.67723916
22Collecting duct acid secretion_Homo sapiens_hsa049661.64549878
23Serotonergic synapse_Homo sapiens_hsa047261.59404787
24Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.58513055
25Glycosaminoglycan degradation_Homo sapiens_hsa005311.56677133
26Calcium signaling pathway_Homo sapiens_hsa040201.55390007
27Long-term depression_Homo sapiens_hsa047301.52524106
28Oxytocin signaling pathway_Homo sapiens_hsa049211.51997890
29GnRH signaling pathway_Homo sapiens_hsa049121.38161999
30Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.37050553
31Sphingolipid metabolism_Homo sapiens_hsa006001.34531694
32Lysosome_Homo sapiens_hsa041421.30748624
33Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.28233541
34Gap junction_Homo sapiens_hsa045401.28054041
35Vibrio cholerae infection_Homo sapiens_hsa051101.26497903
36Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.26079615
37Pancreatic secretion_Homo sapiens_hsa049721.25938172
38Type II diabetes mellitus_Homo sapiens_hsa049301.21680789
39Other glycan degradation_Homo sapiens_hsa005111.19831074
40cAMP signaling pathway_Homo sapiens_hsa040241.17881725
41Estrogen signaling pathway_Homo sapiens_hsa049151.17404441
42alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.16134042
43Phosphatidylinositol signaling system_Homo sapiens_hsa040701.12128586
44Glioma_Homo sapiens_hsa052141.08114043
45Ether lipid metabolism_Homo sapiens_hsa005651.05966704
46cGMP-PKG signaling pathway_Homo sapiens_hsa040221.03683773
47Nitrogen metabolism_Homo sapiens_hsa009101.00182987
48Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.99994990
49Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.97877311
50Mineral absorption_Homo sapiens_hsa049780.96843581
51Melanogenesis_Homo sapiens_hsa049160.94588702
52Vascular smooth muscle contraction_Homo sapiens_hsa042700.90730043
53Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.90321660
54Histidine metabolism_Homo sapiens_hsa003400.89767636
55ErbB signaling pathway_Homo sapiens_hsa040120.89507783
56Cardiac muscle contraction_Homo sapiens_hsa042600.88759594
57Linoleic acid metabolism_Homo sapiens_hsa005910.87579406
58Thyroid hormone synthesis_Homo sapiens_hsa049180.86514842
59Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.82747801
60Axon guidance_Homo sapiens_hsa043600.80993215
61Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.80562880
62ABC transporters_Homo sapiens_hsa020100.79861535
63Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.76592453
64Carbohydrate digestion and absorption_Homo sapiens_hsa049730.74386107
65Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.73215513
66Tryptophan metabolism_Homo sapiens_hsa003800.73097400
67Phospholipase D signaling pathway_Homo sapiens_hsa040720.71838221
68Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.71810591
69Glucagon signaling pathway_Homo sapiens_hsa049220.69110721
70Dorso-ventral axis formation_Homo sapiens_hsa043200.68844150
71Primary bile acid biosynthesis_Homo sapiens_hsa001200.68097636
72Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.67410121
73Dilated cardiomyopathy_Homo sapiens_hsa054140.65296224
74Protein digestion and absorption_Homo sapiens_hsa049740.65170495
75Type I diabetes mellitus_Homo sapiens_hsa049400.64206313
76VEGF signaling pathway_Homo sapiens_hsa043700.63167710
77Choline metabolism in cancer_Homo sapiens_hsa052310.62970515
78Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.62480231
79Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.62398266
80ECM-receptor interaction_Homo sapiens_hsa045120.62073283
81beta-Alanine metabolism_Homo sapiens_hsa004100.61071954
82Prion diseases_Homo sapiens_hsa050200.60656872
83Glycerolipid metabolism_Homo sapiens_hsa005610.60634443
84Neurotrophin signaling pathway_Homo sapiens_hsa047220.60229036
85Bile secretion_Homo sapiens_hsa049760.59924959
86Phototransduction_Homo sapiens_hsa047440.59513950
87Oocyte meiosis_Homo sapiens_hsa041140.58386852
88Amoebiasis_Homo sapiens_hsa051460.55673383
89MAPK signaling pathway_Homo sapiens_hsa040100.55577020
90Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.54081176
91Tight junction_Homo sapiens_hsa045300.52615256
92Regulation of autophagy_Homo sapiens_hsa041400.51667787
93Inositol phosphate metabolism_Homo sapiens_hsa005620.51594821
94Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.50886038
95Insulin resistance_Homo sapiens_hsa049310.50498927
96Focal adhesion_Homo sapiens_hsa045100.50132003
97Ras signaling pathway_Homo sapiens_hsa040140.48509233
98Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.47554264
99Circadian rhythm_Homo sapiens_hsa047100.47351880
100Rheumatoid arthritis_Homo sapiens_hsa053230.47249568
101Osteoclast differentiation_Homo sapiens_hsa043800.47079694
102Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.46884716
103Alzheimers disease_Homo sapiens_hsa050100.46872029
104Thyroid hormone signaling pathway_Homo sapiens_hsa049190.45986277
105Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.45633349
106Platelet activation_Homo sapiens_hsa046110.45361828
107Insulin signaling pathway_Homo sapiens_hsa049100.45181093
108TNF signaling pathway_Homo sapiens_hsa046680.44045576
109Non-small cell lung cancer_Homo sapiens_hsa052230.43987170
110mTOR signaling pathway_Homo sapiens_hsa041500.43956729
111Rap1 signaling pathway_Homo sapiens_hsa040150.43808937
112Melanoma_Homo sapiens_hsa052180.43457201
113SNARE interactions in vesicular transport_Homo sapiens_hsa041300.43057565
114Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.42777934
115Sphingolipid signaling pathway_Homo sapiens_hsa040710.41771812
116Alcoholism_Homo sapiens_hsa050340.40811472
117Longevity regulating pathway - mammal_Homo sapiens_hsa042110.40724372
118Endometrial cancer_Homo sapiens_hsa052130.39649351
119Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.37221303
120Ovarian steroidogenesis_Homo sapiens_hsa049130.35507785
121Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.35277787
122Endocytosis_Homo sapiens_hsa041440.35094811
123Butanoate metabolism_Homo sapiens_hsa006500.33173928
124Arginine biosynthesis_Homo sapiens_hsa002200.32373726
125Prolactin signaling pathway_Homo sapiens_hsa049170.31833178
126Maturity onset diabetes of the young_Homo sapiens_hsa049500.29302290
127Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.29292561
128Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.27955042
129Renal cell carcinoma_Homo sapiens_hsa052110.26991257
130African trypanosomiasis_Homo sapiens_hsa051430.26618440

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