CCDC15

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of DNA methylation (GO:0044030)5.16352052
2nuclear pore complex assembly (GO:0051292)4.87256877
3regulation of meiosis I (GO:0060631)4.84674136
4meiotic cell cycle (GO:0051321)4.75500722
5nuclear pore organization (GO:0006999)4.55606067
6kinetochore organization (GO:0051383)4.53961117
7regulation of double-strand break repair via homologous recombination (GO:0010569)4.49347307
8positive regulation of mitotic sister chromatid separation (GO:1901970)4.47499076
9positive regulation of mitotic metaphase/anaphase transition (GO:0045842)4.47499076
10positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)4.47499076
11mitotic sister chromatid cohesion (GO:0007064)4.44040755
12piRNA metabolic process (GO:0034587)4.42986958
13protein localization to kinetochore (GO:0034501)4.42273824
14positive regulation of histone H3-K4 methylation (GO:0051571)4.41820544
15synapsis (GO:0007129)4.34327506
16chromatin remodeling at centromere (GO:0031055)4.26198467
17CENP-A containing nucleosome assembly (GO:0034080)4.25692324
18DNA replication-independent nucleosome organization (GO:0034724)4.19539809
19DNA replication-independent nucleosome assembly (GO:0006336)4.19539809
20positive regulation of chromosome segregation (GO:0051984)4.15430655
21mitotic sister chromatid segregation (GO:0000070)4.12045988
22meiotic chromosome segregation (GO:0045132)4.07845229
23mitotic chromosome condensation (GO:0007076)4.03415880
24DNA unwinding involved in DNA replication (GO:0006268)4.02488628
25protein localization to chromosome, centromeric region (GO:0071459)4.01885644
26DNA replication checkpoint (GO:0000076)4.01878401
27mitotic metaphase plate congression (GO:0007080)4.00103978
28regulation of centriole replication (GO:0046599)3.99901297
29regulation of spindle organization (GO:0090224)3.93886880
30pore complex assembly (GO:0046931)3.93517542
31sister chromatid segregation (GO:0000819)3.93321576
32DNA double-strand break processing (GO:0000729)3.91717563
33resolution of meiotic recombination intermediates (GO:0000712)3.85114768
34retinal cone cell development (GO:0046549)3.85084709
35rRNA methylation (GO:0031167)3.82595024
36DNA strand elongation involved in DNA replication (GO:0006271)3.77447268
37regulation of mitotic spindle organization (GO:0060236)3.76208101
38attachment of spindle microtubules to kinetochore (GO:0008608)3.75760920
39DNA replication initiation (GO:0006270)3.74725524
40kinetochore assembly (GO:0051382)3.73861048
41microtubule depolymerization (GO:0007019)3.73775203
42metaphase plate congression (GO:0051310)3.73771278
43telomere maintenance via recombination (GO:0000722)3.73649308
44telomere maintenance via semi-conservative replication (GO:0032201)3.72172924
45histone exchange (GO:0043486)3.71789226
46spindle checkpoint (GO:0031577)3.68628990
47mitotic recombination (GO:0006312)3.67625578
48DNA strand elongation (GO:0022616)3.66966457
49DNA topological change (GO:0006265)3.66862062
50IMP biosynthetic process (GO:0006188)3.66493239
51mitotic nuclear envelope disassembly (GO:0007077)3.65498572
52chromosome organization involved in meiosis (GO:0070192)3.60907949
53translesion synthesis (GO:0019985)3.58519363
54postreplication repair (GO:0006301)3.57893204
55establishment of chromosome localization (GO:0051303)3.57855914
56establishment of mitotic spindle localization (GO:0040001)3.52265373
57regulation of sister chromatid cohesion (GO:0007063)3.51070135
58regulation of centrosome cycle (GO:0046605)3.50105949
59recombinational repair (GO:0000725)3.48688430
60double-strand break repair via homologous recombination (GO:0000724)3.48312346
61mitotic G2/M transition checkpoint (GO:0044818)3.48189175
62histone-serine phosphorylation (GO:0035404)3.44844985
63rRNA modification (GO:0000154)3.43945269
64intra-S DNA damage checkpoint (GO:0031573)3.43560233
65chromatin assembly or disassembly (GO:0006333)3.41177724
66nuclear envelope disassembly (GO:0051081)3.41050571
67membrane disassembly (GO:0030397)3.41050571
68regulation of female gonad development (GO:2000194)3.39386396
69regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.39269262
70regulation of mitotic spindle checkpoint (GO:1903504)3.39269262
71regulation of histone H3-K9 methylation (GO:0051570)3.35496765
72establishment of mitotic spindle orientation (GO:0000132)3.35233047
73regulation of DNA endoreduplication (GO:0032875)3.34940696
74regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.34341821
75proteasome assembly (GO:0043248)3.31702822
76negative regulation of phagocytosis (GO:0050765)3.31503807
77negative regulation of chromosome segregation (GO:0051985)3.31221542
78male meiosis I (GO:0007141)3.31195412
79mitotic spindle checkpoint (GO:0071174)3.31182186
80regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.30072404
81IMP metabolic process (GO:0046040)3.29220298
82negative regulation of mitotic sister chromatid segregation (GO:0033048)3.29146239
83negative regulation of mitotic sister chromatid separation (GO:2000816)3.29146239
84negative regulation of sister chromatid segregation (GO:0033046)3.29146239
85negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.29146239
86negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.29146239
87meiotic cell cycle process (GO:1903046)3.25970275
88female gamete generation (GO:0007292)3.24381331
89centrosome duplication (GO:0051298)3.24111836
90regulation of chromosome segregation (GO:0051983)3.19896652
91ATP-dependent chromatin remodeling (GO:0043044)3.19126867
92DNA methylation involved in gamete generation (GO:0043046)3.19040281
93regulation of spindle checkpoint (GO:0090231)3.16176268
94centrosome organization (GO:0051297)3.14959676
95telomere maintenance (GO:0000723)3.14607711
96telomere maintenance via telomere lengthening (GO:0010833)3.14187493
97mitotic spindle assembly checkpoint (GO:0007094)3.12489278
98spindle assembly checkpoint (GO:0071173)3.12093502
99DNA ligation (GO:0006266)3.11815933
100chromosome segregation (GO:0007059)3.09933238
101telomere organization (GO:0032200)3.08918889
102DNA conformation change (GO:0071103)3.08723902
103DNA packaging (GO:0006323)3.07901947
104DNA synthesis involved in DNA repair (GO:0000731)3.06847439
105regulation of centrosome duplication (GO:0010824)3.06383920
106muscle organ morphogenesis (GO:0048644)3.05236480
107regulation of acrosome reaction (GO:0060046)3.05075290
108maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.04320448
109sister chromatid cohesion (GO:0007062)3.03774415
110protein localization to chromosome (GO:0034502)3.02967777
111chromosome condensation (GO:0030261)3.02483996
112DNA duplex unwinding (GO:0032508)3.02371271
113regulation of mitotic metaphase/anaphase transition (GO:0030071)3.01689135
114DNA replication-dependent nucleosome assembly (GO:0006335)3.01651279
115DNA replication-dependent nucleosome organization (GO:0034723)3.01651279
116DNA geometric change (GO:0032392)3.01363445
117centriole replication (GO:0007099)3.00156403
118regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.98785269
119protein K6-linked ubiquitination (GO:0085020)2.97782647
120regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.97410229
121nucleotide-excision repair, DNA gap filling (GO:0006297)2.95321853
122centriole assembly (GO:0098534)2.94020831
123regulation of nuclear cell cycle DNA replication (GO:0033262)2.94004271
124negative regulation of histone methylation (GO:0031061)2.93566108
125regulation of sister chromatid segregation (GO:0033045)2.87775056
126regulation of mitotic sister chromatid separation (GO:0010965)2.87775056
127regulation of mitotic sister chromatid segregation (GO:0033047)2.87775056
128V(D)J recombination (GO:0033151)2.86635387
129negative regulation of DNA-dependent DNA replication (GO:2000104)2.86275599
130replication fork processing (GO:0031297)2.84768613
131establishment of spindle orientation (GO:0051294)2.83199226
132negative regulation of histone acetylation (GO:0035067)2.78512044
133RNA-dependent DNA replication (GO:0006278)2.77607399
134monoubiquitinated protein deubiquitination (GO:0035520)2.73768636
135DNA-dependent DNA replication (GO:0006261)2.73381751
136DNA damage response, detection of DNA damage (GO:0042769)2.71985498

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human5.97948631
2* E2F4_17652178_ChIP-ChIP_JURKAT_Human5.00486266
3FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human4.11246596
4EGR1_19374776_ChIP-ChIP_THP-1_Human3.91322222
5E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.44982587
6EZH2_22144423_ChIP-Seq_EOC_Human3.35461065
7TP63_19390658_ChIP-ChIP_HaCaT_Human2.78514599
8E2F1_21310950_ChIP-Seq_MCF-7_Human2.61070620
9FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.51154231
10AR_21909140_ChIP-Seq_LNCAP_Human2.50368644
11KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.46028030
12MYC_18555785_ChIP-Seq_MESCs_Mouse2.42578233
13* MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.33327165
14MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.33056569
15SALL1_21062744_ChIP-ChIP_HESCs_Human2.18345333
16BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.14730579
17BP1_19119308_ChIP-ChIP_Hs578T_Human2.05947476
18E2F7_22180533_ChIP-Seq_HELA_Human11.3235991
19EST1_17652178_ChIP-ChIP_JURKAT_Human1.94116150
20ZNF274_21170338_ChIP-Seq_K562_Hela1.91300268
21FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.90667061
22GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.88103023
23MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.87427001
24SCL_19346495_ChIP-Seq_HPC-7_Human1.86454256
25KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.84809775
26* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.83027946
27MYC_19030024_ChIP-ChIP_MESCs_Mouse1.81921432
28SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.72353824
29CIITA_25753668_ChIP-Seq_RAJI_Human1.69082297
30PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.68389939
31HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.67981488
32ELK1_19687146_ChIP-ChIP_HELA_Human1.63150036
33* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.60245371
34HOXB4_20404135_ChIP-ChIP_EML_Mouse1.55934008
35FOXP3_21729870_ChIP-Seq_TREG_Human1.54784982
36VDR_23849224_ChIP-Seq_CD4+_Human1.52535579
37MYC_19079543_ChIP-ChIP_MESCs_Mouse1.52011089
38MYCN_18555785_ChIP-Seq_MESCs_Mouse1.50442385
39CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.50387994
40* ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.48593843
41* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.48276453
42VDR_22108803_ChIP-Seq_LS180_Human1.45820043
43STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.43754154
44IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.39220624
45MYC_18358816_ChIP-ChIP_MESCs_Mouse1.38697489
46NOTCH1_21737748_ChIP-Seq_TLL_Human1.37248739
47MYB_26560356_Chip-Seq_TH2_Human1.35555884
48PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.33581813
49SOX2_18555785_ChIP-Seq_MESCs_Mouse1.31471264
50IRF8_21731497_ChIP-ChIP_J774_Mouse1.29999001
51PADI4_21655091_ChIP-ChIP_MCF-7_Human1.29364358
52* MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.29260823
53FLI1_27457419_Chip-Seq_LIVER_Mouse1.28602813
54CREB1_15753290_ChIP-ChIP_HEK293T_Human1.25494083
55YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.20427013
56MYB_21317192_ChIP-Seq_ERMYB_Mouse1.20279312
57THAP11_20581084_ChIP-Seq_MESCs_Mouse1.20218046
58HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.20109394
59IGF1R_20145208_ChIP-Seq_DFB_Human1.18831617
60STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.18739618
61MYC_18940864_ChIP-ChIP_HL60_Human1.18607616
62MYC_22102868_ChIP-Seq_BL_Human1.18030389
63EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.17433937
64SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.17402076
65TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.16774145
66XRN2_22483619_ChIP-Seq_HELA_Human1.15701944
67TTF2_22483619_ChIP-Seq_HELA_Human1.13912586
68ERG_20887958_ChIP-Seq_HPC-7_Mouse1.13851556
69* MYB_26560356_Chip-Seq_TH1_Human1.13805127
70NANOG_18555785_ChIP-Seq_MESCs_Mouse1.13540182
71GBX2_23144817_ChIP-Seq_PC3_Human1.11877998
72* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.10883714
73P300_19829295_ChIP-Seq_ESCs_Human1.05798311
74PCGF2_27294783_Chip-Seq_ESCs_Mouse1.05626966
75PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.05441351
76FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.04961320
77KDM5A_27292631_Chip-Seq_BREAST_Human1.04438421
78NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.03154673
79CTBP2_25329375_ChIP-Seq_LNCAP_Human1.02734557
80TAF15_26573619_Chip-Seq_HEK293_Human1.01841400
81GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.01782915
82* GABP_17652178_ChIP-ChIP_JURKAT_Human1.01448080
83IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.00688728
84* EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.00006686
85UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.98642640
86IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.98596516
87CBP_20019798_ChIP-Seq_JUKART_Human0.98596516
88SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.96994218
89ELF1_17652178_ChIP-ChIP_JURKAT_Human0.96226933
90SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.95656124
91FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.94956711
92SPI1_23547873_ChIP-Seq_NB4_Human0.93797277
93ZFP57_27257070_Chip-Seq_ESCs_Mouse0.92117365
94TP53_22573176_ChIP-Seq_HFKS_Human0.91797554
95* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.91772069
96EWS_26573619_Chip-Seq_HEK293_Human0.91529200
97POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.90632717
98AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.89469422
99MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.89302496
100ETS1_20019798_ChIP-Seq_JURKAT_Human0.88553917
101DCP1A_22483619_ChIP-Seq_HELA_Human0.88254525
102TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.88235128
103MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.87531370
104PKCTHETA_26484144_Chip-Seq_BREAST_Human0.87135882
105GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.86274552
106RBPJ_22232070_ChIP-Seq_NCS_Mouse0.85896526
107POU5F1_16153702_ChIP-ChIP_HESCs_Human0.85206861
108STAT4_19710469_ChIP-ChIP_TH1__Mouse0.85127618
109ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.84138838
110ER_23166858_ChIP-Seq_MCF-7_Human0.83653183
111JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.83265079
112CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.82817384
113E2F1_18555785_ChIP-Seq_MESCs_Mouse0.82176586
114HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.82037735
115SOX2_16153702_ChIP-ChIP_HESCs_Human0.79121079
116TOP2B_26459242_ChIP-Seq_MCF-7_Human0.78227265
117PCGF2_27294783_Chip-Seq_NPCs_Mouse0.77589243
118EZH2_27294783_Chip-Seq_NPCs_Mouse0.77537748
119CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.77505025
120CTBP1_25329375_ChIP-Seq_LNCAP_Human0.77501598
121POU3F2_20337985_ChIP-ChIP_501MEL_Human0.77279325
122RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.77256660
123POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.77238902
124NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.76993097
125NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.76639845
126STAT3_23295773_ChIP-Seq_U87_Human0.76515931
127CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.75153594
128HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.74562492
129RUNX1_22412390_ChIP-Seq_EML_Mouse0.73474975
130FUS_26573619_Chip-Seq_HEK293_Human0.73441841
131* GABP_19822575_ChIP-Seq_HepG2_Human0.72318736
132NFE2_27457419_Chip-Seq_LIVER_Mouse0.71102810
133ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.70981427
134GATA2_22383799_ChIP-Seq_G1ME_Mouse0.69596112
135* UTX_26944678_Chip-Seq_JUKART_Human0.69549146
136IRF1_19129219_ChIP-ChIP_H3396_Human0.67276622
137* SRF_21415370_ChIP-Seq_HL-1_Mouse0.66926921
138RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.66923145
139BRD4_27068464_Chip-Seq_AML-cells_Mouse0.66456800

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability4.53644651
2MP0008057_abnormal_DNA_replication4.23174841
3MP0003693_abnormal_embryo_hatching3.82310241
4MP0002396_abnormal_hematopoietic_system3.63588853
5MP0003111_abnormal_nucleus_morphology3.43305057
6MP0008877_abnormal_DNA_methylation3.27775440
7MP0000569_abnormal_digit_pigmentation3.26599365
8MP0008007_abnormal_cellular_replicative2.99408772
9MP0003077_abnormal_cell_cycle2.91294130
10MP0008789_abnormal_olfactory_epithelium2.65198769
11MP0004808_abnormal_hematopoietic_stem2.53783886
12MP0006292_abnormal_olfactory_placode2.50731821
13MP0004957_abnormal_blastocyst_morpholog2.33902290
14MP0008058_abnormal_DNA_repair2.24210196
15MP0010352_gastrointestinal_tract_polyps2.14863349
16MP0005174_abnormal_tail_pigmentation2.04905018
17MP0005394_taste/olfaction_phenotype2.00166466
18MP0005499_abnormal_olfactory_system2.00166466
19MP0002234_abnormal_pharynx_morphology1.99323475
20MP0003787_abnormal_imprinting1.95802175
21MP0005397_hematopoietic_system_phenotyp1.82713049
22MP0001545_abnormal_hematopoietic_system1.82713049
23MP0005395_other_phenotype1.76144810
24MP0003763_abnormal_thymus_physiology1.71378812
25MP0001293_anophthalmia1.70378402
26MP0003950_abnormal_plasma_membrane1.69460681
27MP0003786_premature_aging1.62806200
28MP0002877_abnormal_melanocyte_morpholog1.51563255
29MP0000350_abnormal_cell_proliferation1.47029420
30MP0009697_abnormal_copulation1.46855027
31MP0003699_abnormal_female_reproductive1.45851242
32MP0003890_abnormal_embryonic-extraembry1.45525681
33MP0002398_abnormal_bone_marrow1.45451165
34MP0006072_abnormal_retinal_apoptosis1.45137508
35MP0001835_abnormal_antigen_presentation1.44341450
36MP0001929_abnormal_gametogenesis1.43687856
37MP0000490_abnormal_crypts_of1.43564912
38MP0000015_abnormal_ear_pigmentation1.43040679
39MP0010307_abnormal_tumor_latency1.41362824
40MP0002166_altered_tumor_susceptibility1.38661538
41MP0002160_abnormal_reproductive_system1.37890832
42MP0005076_abnormal_cell_differentiation1.36971192
43MP0003123_paternal_imprinting1.36010007
44MP0003121_genomic_imprinting1.35237613
45MP0001800_abnormal_humoral_immune1.34624507
46MP0000372_irregular_coat_pigmentation1.34288214
47MP0003136_yellow_coat_color1.33974412
48MP0002210_abnormal_sex_determination1.32715997
49MP0008932_abnormal_embryonic_tissue1.31860063
50MP0002006_tumorigenesis1.30177252
51MP0000703_abnormal_thymus_morphology1.28663073
52MP0000427_abnormal_hair_cycle1.28066100
53MP0002095_abnormal_skin_pigmentation1.27034043
54MP0005257_abnormal_intraocular_pressure1.25338581
55MP0002132_abnormal_respiratory_system1.18503010
56MP0002019_abnormal_tumor_incidence1.18420948
57MP0002722_abnormal_immune_system1.17629513
58MP0002161_abnormal_fertility/fecundity1.17204926
59MP0001730_embryonic_growth_arrest1.16932852
60MP0003937_abnormal_limbs/digits/tail_de1.15960371
61MP0000689_abnormal_spleen_morphology1.15727732
62MP0005075_abnormal_melanosome_morpholog1.15682180
63MP0000716_abnormal_immune_system1.10455763
64MP0000631_abnormal_neuroendocrine_gland1.09763337
65MP0004510_myositis1.08110882
66MP0005645_abnormal_hypothalamus_physiol1.08057848
67MP0000313_abnormal_cell_death1.07839072
68MP0000653_abnormal_sex_gland1.06232584
69MP0002233_abnormal_nose_morphology1.05721201
70MP0005380_embryogenesis_phenotype1.05640223
71MP0001672_abnormal_embryogenesis/_devel1.05640223
72MP0004147_increased_porphyrin_level1.05428356
73MP0005408_hypopigmentation1.05423239
74MP0001145_abnormal_male_reproductive1.03098201
75MP0002452_abnormal_antigen_presenting1.02692561
76MP0010030_abnormal_orbit_morphology1.02436290
77MP0005551_abnormal_eye_electrophysiolog1.00655925
78MP0001849_ear_inflammation0.99915842
79MP0002429_abnormal_blood_cell0.99756343
80MP0002420_abnormal_adaptive_immunity0.99197868
81MP0004782_abnormal_surfactant_physiolog0.98521293
82MP0002163_abnormal_gland_morphology0.98038971
83MP0005360_urolithiasis0.97474058
84MP0002938_white_spotting0.97243547
85MP0004043_abnormal_pH_regulation0.96265032
86MP0005671_abnormal_response_to0.96213762
87MP0003718_maternal_effect0.95961612
88MP0001819_abnormal_immune_cell0.95905124
89MP0002009_preneoplasia0.94076713
90MP0009379_abnormal_foot_pigmentation0.93233451
91MP0001119_abnormal_female_reproductive0.91568796
92MP0001286_abnormal_eye_development0.90636456
93MP0002075_abnormal_coat/hair_pigmentati0.90324132
94MP0003984_embryonic_growth_retardation0.90290847
95MP0001915_intracranial_hemorrhage0.89979527
96MP0001697_abnormal_embryo_size0.89223683
97MP0003698_abnormal_male_reproductive0.87981676
98MP0002085_abnormal_embryonic_tissue0.87553243
99MP0008995_early_reproductive_senescence0.87478642
100MP0002723_abnormal_immune_serum0.86228179
101MP0002088_abnormal_embryonic_growth/wei0.85810002
102MP0000678_abnormal_parathyroid_gland0.84670156
103MP0009785_altered_susceptibility_to0.83883589
104MP0002086_abnormal_extraembryonic_tissu0.83550160
105MP0005410_abnormal_fertilization0.81815154
106MP0002092_abnormal_eye_morphology0.80568503
107MP0000685_abnormal_immune_system0.80467665
108MP0005464_abnormal_platelet_physiology0.79372474
109MP0010155_abnormal_intestine_physiology0.78904388
110MP0001984_abnormal_olfaction0.78724386
111MP0000647_abnormal_sebaceous_gland0.78601313
112MP0003755_abnormal_palate_morphology0.78494386
113MP0002928_abnormal_bile_duct0.78375587
114MP0001529_abnormal_vocalization0.77772230
115MP0002080_prenatal_lethality0.76572229
116MP0001324_abnormal_eye_pigmentation0.76463816
117MP0003941_abnormal_skin_development0.76408986
118MP0005253_abnormal_eye_physiology0.75064373
119MP0005171_absent_coat_pigmentation0.74876696
120MP0003943_abnormal_hepatobiliary_system0.74704252
121MP0002084_abnormal_developmental_patter0.73754900
122MP0006054_spinal_hemorrhage0.72226040
123MP0005389_reproductive_system_phenotype0.72199757
124MP0001919_abnormal_reproductive_system0.72192796
125MP0005409_darkened_coat_color0.72083218
126MP0000358_abnormal_cell_content/0.71921582
127MP0003252_abnormal_bile_duct0.71917789
128MP0000566_synostosis0.71795816
129MP0002277_abnormal_respiratory_mucosa0.71582855
130MP0000371_diluted_coat_color0.71374390
131MP0001873_stomach_inflammation0.71219375
132MP0003119_abnormal_digestive_system0.71141055
133MP0000049_abnormal_middle_ear0.70766672
134MP0003186_abnormal_redox_activity0.70242514
135MP0010234_abnormal_vibrissa_follicle0.69950425
136MP0001186_pigmentation_phenotype0.69780166
137MP0002405_respiratory_system_inflammati0.68802957
138MP0005647_abnormal_sex_gland0.67494435
139MP0006035_abnormal_mitochondrial_morpho0.66161940
140MP0004197_abnormal_fetal_growth/weight/0.65773859
141MP0006036_abnormal_mitochondrial_physio0.65624529
142MP0003936_abnormal_reproductive_system0.65403775
143MP0002090_abnormal_vision0.64359281
144MP0005187_abnormal_penis_morphology0.62229313
145MP0003935_abnormal_craniofacial_develop0.61439292
146MP0004142_abnormal_muscle_tone0.60714523
147MP0005391_vision/eye_phenotype0.59891748
148MP0000428_abnormal_craniofacial_morphol0.58596943
149MP0001764_abnormal_homeostasis0.57274811

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)4.43499435
2Volvulus (HP:0002580)4.36058582
3Acute myeloid leukemia (HP:0004808)4.06504465
4Supernumerary spleens (HP:0009799)3.99280861
5Lip pit (HP:0100267)3.77051480
6Chromosomal breakage induced by crosslinking agents (HP:0003221)3.73804423
7Asymmetry of the thorax (HP:0001555)3.58425363
8Birth length less than 3rd percentile (HP:0003561)3.57965445
9Abnormality of the duodenum (HP:0002246)3.44909307
10Abnormality of the renal collecting system (HP:0004742)3.30148121
11Abnormality of the fingertips (HP:0001211)3.20008248
12Abnormality of chromosome stability (HP:0003220)3.19074329
13Oligodactyly (hands) (HP:0001180)3.18137322
14Facial hemangioma (HP:0000329)3.12406240
15Absent frontal sinuses (HP:0002688)2.97114024
16Tubulointerstitial nephritis (HP:0001970)2.95272384
17Chronic sinusitis (HP:0011109)2.94954903
18Median cleft lip (HP:0000161)2.86061725
19Septo-optic dysplasia (HP:0100842)2.84628449
20Triphalangeal thumb (HP:0001199)2.83865245
21Myelodysplasia (HP:0002863)2.81087721
22Urethral obstruction (HP:0000796)2.74843953
23Colon cancer (HP:0003003)2.72929288
24Aplastic anemia (HP:0001915)2.71880269
25Increased nuchal translucency (HP:0010880)2.69566186
26Aplasia/Hypoplasia of the uvula (HP:0010293)2.68633666
27Spinal cord lesions (HP:0100561)2.67575707
28Syringomyelia (HP:0003396)2.67575707
29Abnormality of the preputium (HP:0100587)2.67099665
30Renal cortical cysts (HP:0000803)2.66123793
31Abnormality of cochlea (HP:0000375)2.64824265
32Cutaneous melanoma (HP:0012056)2.64443324
33Long eyelashes (HP:0000527)2.52680605
34Abnormality of the renal medulla (HP:0100957)2.52162289
35Abnormality of midbrain morphology (HP:0002418)2.51620291
36Molar tooth sign on MRI (HP:0002419)2.51620291
37Ectopic kidney (HP:0000086)2.47806088
38Clubbing of toes (HP:0100760)2.45052657
39Reticulocytopenia (HP:0001896)2.41453333
40Short tibia (HP:0005736)2.37571483
41Short middle phalanx of the 5th finger (HP:0004220)2.37119059
42Aplasia/Hypoplasia of the tibia (HP:0005772)2.35345439
43Oligodactyly (HP:0012165)2.34101626
44Recurrent bronchitis (HP:0002837)2.32141079
45Absent septum pellucidum (HP:0001331)2.32024315
46Meckel diverticulum (HP:0002245)2.31951082
47Absent radius (HP:0003974)2.31551516
48Aplasia/Hypoplasia of the fovea (HP:0008060)2.30492355
49Hypoplasia of the fovea (HP:0007750)2.30492355
50Papillary thyroid carcinoma (HP:0002895)2.29543384
51Short thumb (HP:0009778)2.28187534
52Duplicated collecting system (HP:0000081)2.27365596
53Sloping forehead (HP:0000340)2.26751039
54Dynein arm defect of respiratory motile cilia (HP:0012255)2.26519712
55Absent/shortened dynein arms (HP:0200106)2.26519712
56Abnormality of abdominal situs (HP:0011620)2.26404760
57Abdominal situs inversus (HP:0003363)2.26404760
58Stenosis of the external auditory canal (HP:0000402)2.25239739
59Abnormal spermatogenesis (HP:0008669)2.25143756
60Thyroiditis (HP:0100646)2.23364030
61Abnormality of the ileum (HP:0001549)2.22755477
62Deep philtrum (HP:0002002)2.21269067
63Intestinal atresia (HP:0011100)2.20138341
64Arteriovenous malformation (HP:0100026)2.19460083
65Embryonal neoplasm (HP:0002898)2.18262128
66Absent thumb (HP:0009777)2.17276800
67Abnormal respiratory motile cilium morphology (HP:0005938)2.16222271
68Abnormal respiratory epithelium morphology (HP:0012253)2.16222271
69Pancreatic cysts (HP:0001737)2.15813555
70Aplasia/Hypoplasia of the tongue (HP:0010295)2.15258525
71Duodenal stenosis (HP:0100867)2.15115075
72Small intestinal stenosis (HP:0012848)2.15115075
73Medial flaring of the eyebrow (HP:0010747)2.14965010
74Selective tooth agenesis (HP:0001592)2.13481812
75Aplasia involving forearm bones (HP:0009822)2.12798243
76Absent forearm bone (HP:0003953)2.12798243
77Abnormality of DNA repair (HP:0003254)2.11528754
78Thyroid carcinoma (HP:0002890)2.09468974
79Patellar aplasia (HP:0006443)2.08743701
80Abnormality of the renal cortex (HP:0011035)2.06856600
81Abnormality of the fovea (HP:0000493)2.06519772
82Abnormality of the septum pellucidum (HP:0007375)2.05816995
83B lymphocytopenia (HP:0010976)2.01614417
84Abnormality of B cell number (HP:0010975)2.01614417
85Astigmatism (HP:0000483)2.01593617
86Prominent nose (HP:0000448)2.01062525
87Abnormal number of incisors (HP:0011064)2.00924066
88Cafe-au-lait spot (HP:0000957)2.00469430
89Premature graying of hair (HP:0002216)1.99499002
90Muscle fiber atrophy (HP:0100295)1.98419762
91Abnormality of the carotid arteries (HP:0005344)1.97718220
92Horseshoe kidney (HP:0000085)1.96796051
93Nephronophthisis (HP:0000090)1.96769330
94Abnormal biliary tract physiology (HP:0012439)1.96342093
95Bile duct proliferation (HP:0001408)1.96342093
96Capillary hemangiomas (HP:0005306)1.95141998
97Abnormal delayed hypersensitivity skin test (HP:0002963)1.93483192
98Abnormality of T cells (HP:0002843)1.92165632
99Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.91496638
100Acute lymphatic leukemia (HP:0006721)1.89773578
101Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.88738068
102Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.86585023
103Hypoplasia of the thymus (HP:0000778)1.85595496
104Type 2 muscle fiber atrophy (HP:0003554)1.85225549
105Abnormal gallbladder physiology (HP:0012438)1.84194239
106Cholecystitis (HP:0001082)1.84194239
107Abnormal lung lobation (HP:0002101)1.83918181
108Breast hypoplasia (HP:0003187)1.82934170
109Abnormal respiratory motile cilium physiology (HP:0012261)1.82652708
110Prostate neoplasm (HP:0100787)1.82514964
111Pulmonary fibrosis (HP:0002206)1.82495943
112Aplasia/Hypoplasia of the patella (HP:0006498)1.81368827
113Medulloblastoma (HP:0002885)1.80764347
114Proximal placement of thumb (HP:0009623)1.80174161
115Oligohydramnios (HP:0001562)1.80109814
116Optic nerve hypoplasia (HP:0000609)1.79866037
117Abnormality of T cell physiology (HP:0011840)1.79527728
118Bone marrow hypocellularity (HP:0005528)1.79092082
119Deviation of the thumb (HP:0009603)1.78988914
120Preaxial hand polydactyly (HP:0001177)1.78856123
121Limb hypertonia (HP:0002509)1.78630186
122Aganglionic megacolon (HP:0002251)1.78475647
123Increased number of teeth (HP:0011069)1.77804922
124Bronchitis (HP:0012387)1.77391934
125Abnormality of the labia minora (HP:0012880)1.77177556
126Aplasia/Hypoplasia of the earlobes (HP:0009906)1.76604284
127Embryonal renal neoplasm (HP:0011794)1.75486045
128Choanal atresia (HP:0000453)1.74767482
129Pancreatic fibrosis (HP:0100732)1.74618790
130Nephroblastoma (Wilms tumor) (HP:0002667)1.74592557
131Aplasia/Hypoplasia of the sternum (HP:0006714)1.73801451
132Increased hepatocellular lipid droplets (HP:0006565)1.73688531
133Azoospermia (HP:0000027)1.73681666
134Abnormal ciliary motility (HP:0012262)1.73246605
135Fair hair (HP:0002286)1.72952409
136Microtia (HP:0008551)1.72707287
137Lymphoma (HP:0002665)1.72676778
138High pitched voice (HP:0001620)1.72417591
139IgM deficiency (HP:0002850)1.72100271
140Atresia of the external auditory canal (HP:0000413)1.72012496
141Chronic hepatic failure (HP:0100626)1.71996593
142Sandal gap (HP:0001852)1.71180618
143Optic neuritis (HP:0100653)1.70850547
144Retrobulbar optic neuritis (HP:0100654)1.70850547
145Truncal obesity (HP:0001956)1.70312255
146Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.70161268
147Agammaglobulinemia (HP:0004432)1.70093789
148Chronic otitis media (HP:0000389)1.69780837
149Neoplasm of the oral cavity (HP:0100649)1.69512652
150Periodontitis (HP:0000704)1.69430616
151Abnormality of T cell number (HP:0011839)1.69268913
152Osteomalacia (HP:0002749)1.68460951
153Hyperglycinemia (HP:0002154)1.68431039
154Abnormality of the incisor (HP:0000676)1.67998814
155Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.67849414
156T lymphocytopenia (HP:0005403)1.66820490
157Leukopenia (HP:0001882)1.66587633
158Gastrointestinal atresia (HP:0002589)1.65197537
159Duplication of thumb phalanx (HP:0009942)1.65174707
160Premature ovarian failure (HP:0008209)1.65167675
161Methylmalonic acidemia (HP:0002912)1.65133967
162Impulsivity (HP:0100710)1.64892950
163Congenital primary aphakia (HP:0007707)1.64626324
164Lipid accumulation in hepatocytes (HP:0006561)1.64030012
165Hypophosphatemic rickets (HP:0004912)1.62540220
166Gonadotropin excess (HP:0000837)1.62322887
167Pancytopenia (HP:0001876)1.62275662

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BRD47.03815608
2CDC74.28816063
3MKNK24.03660859
4MKNK13.30384053
5CDK123.10816156
6PLK42.69903334
7FRK2.45846511
8VRK22.40845091
9TRIM282.23631358
10BUB12.14169707
11BRSK22.10723754
12TNIK2.08083583
13ATR2.08003246
14NEK12.07357135
15STK101.89466412
16PLK11.87430756
17WEE11.86892805
18NEK21.84807584
19CDK91.77899503
20NEK91.75670483
21TAF11.75179031
22MAP4K11.70603439
23MAP3K131.60287959
24TAOK31.58500797
25NUAK11.57568657
26PNCK1.55773506
27TTK1.50885498
28RPS6KA41.49070692
29VRK11.48828299
30SRPK11.43151835
31PLK31.42734332
32ARAF1.41126695
33CCNB11.37359181
34TXK1.34827018
35STK31.34026121
36ZAK1.31107508
37MAP3K91.29220780
38CDK71.28314601
39AURKB1.25198084
40TEC1.19636516
41IRAK41.18218771
42WNK31.13654888
43MAP3K141.12404885
44STK391.10735883
45ATM1.09725046
46MAPKAPK51.08771754
47ACVR1B1.07780272
48CDK61.06143538
49STK41.05725560
50CDK41.05158651
51CHEK21.04508016
52CHEK11.03886571
53NEK61.03135028
54TGFBR10.99780508
55BRSK10.98193237
56CDK80.93567349
57STK240.87215263
58MAP3K80.87203734
59SCYL20.86064411
60CHUK0.85429957
61MET0.85287948
62EIF2AK30.83301637
63BTK0.82420097
64BLK0.81901289
65PIM10.81246513
66PRKCI0.80168787
67LATS10.79303920
68STK38L0.78200163
69MAPK130.77613039
70JAK30.76976145
71TLK10.76423223
72MAP4K20.76184300
73KIT0.75144868
74BCR0.74276584
75CDK20.71925410
76FGFR30.71884024
77PDK40.71629605
78PDK30.71629605
79MAP3K40.70018308
80TIE10.68250940
81FGFR20.68034288
82RPS6KB20.67476310
83RAF10.66875487
84ALK0.66443826
85CSF1R0.66411268
86PASK0.64281811
87PBK0.63357497
88TSSK60.62306002
89MELK0.61915549
90MARK30.61329881
91SIK30.59148722
92CSNK1G10.57606795
93EIF2AK10.57522767
94CDK10.56916009
95PINK10.55441360
96EEF2K0.55370110
97MOS0.54278354
98EIF2AK20.50525369
99BCKDK0.49024489
100CSNK1G30.48627941
101CDK30.47025920
102RPS6KB10.46910312
103INSRR0.46485572
104FLT30.43934992
105ERBB30.43657956
106STK160.43616312
107SYK0.43053180
108IKBKB0.42391665
109CSNK1G20.42088462
110AKT30.40968953
111GRK10.40107135
112MUSK0.40004083
113CASK0.39359870
114MST40.38736485
115MAPK140.37523613
116YES10.37438112
117MAP2K30.37389085
118CSNK1A1L0.37381332
119CSNK1E0.35170872
120CSNK2A10.34249977
121TYK20.34141766
122RPS6KA50.33952867
123CSNK1D0.32884966
124PLK20.31803654
125KSR10.31608935
126OXSR10.31454579
127ITK0.31197278
128MTOR0.31038407
129LYN0.30548396
130BRAF0.30281420
131WNK40.29915267
132ADRBK20.29015655
133PKN10.28013473
134CSNK2A20.27814848
135MAPK10.27246933
136PRKDC0.26235012
137AKT10.25221256
138AURKA0.24834481
139GSK3B0.24436997
140LCK0.23715050
141BMPR1B0.22878781
142MAPK30.19854615
143MAPK100.18629332

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.41569816
2Homologous recombination_Homo sapiens_hsa034403.59268251
3Mismatch repair_Homo sapiens_hsa034303.52519064
4Base excision repair_Homo sapiens_hsa034103.29352378
5Cell cycle_Homo sapiens_hsa041103.03146856
6Non-homologous end-joining_Homo sapiens_hsa034502.95198916
7Fanconi anemia pathway_Homo sapiens_hsa034602.78540565
8Caffeine metabolism_Homo sapiens_hsa002322.77176717
9RNA transport_Homo sapiens_hsa030132.43501927
10One carbon pool by folate_Homo sapiens_hsa006702.25141939
11Spliceosome_Homo sapiens_hsa030402.24271230
12RNA degradation_Homo sapiens_hsa030182.15656709
13Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.13755020
14Nucleotide excision repair_Homo sapiens_hsa034202.09104423
15mRNA surveillance pathway_Homo sapiens_hsa030152.02266201
16Protein export_Homo sapiens_hsa030601.97966499
17Basal transcription factors_Homo sapiens_hsa030221.92952552
18RNA polymerase_Homo sapiens_hsa030201.70859059
19Transcriptional misregulation in cancer_Homo sapiens_hsa052021.67715373
20p53 signaling pathway_Homo sapiens_hsa041151.60522903
21Folate biosynthesis_Homo sapiens_hsa007901.58283019
22Systemic lupus erythematosus_Homo sapiens_hsa053221.54193718
23Herpes simplex infection_Homo sapiens_hsa051681.53806417
24NF-kappa B signaling pathway_Homo sapiens_hsa040641.49437922
25Pyrimidine metabolism_Homo sapiens_hsa002401.48587771
26Propanoate metabolism_Homo sapiens_hsa006401.47265457
27Primary immunodeficiency_Homo sapiens_hsa053401.43362533
28Cysteine and methionine metabolism_Homo sapiens_hsa002701.36382800
29Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.35579346
30Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.34825009
31Viral carcinogenesis_Homo sapiens_hsa052031.34731784
32Intestinal immune network for IgA production_Homo sapiens_hsa046721.30972787
33Measles_Homo sapiens_hsa051621.30669434
34Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.29187039
35Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.20944915
36NOD-like receptor signaling pathway_Homo sapiens_hsa046211.19663318
37Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.19273473
38HTLV-I infection_Homo sapiens_hsa051661.16691751
39MicroRNAs in cancer_Homo sapiens_hsa052061.14868270
40Small cell lung cancer_Homo sapiens_hsa052221.14109140
41Huntingtons disease_Homo sapiens_hsa050161.13327707
42Epstein-Barr virus infection_Homo sapiens_hsa051691.12615916
43Oxidative phosphorylation_Homo sapiens_hsa001901.07409157
44Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.06703453
45Fatty acid elongation_Homo sapiens_hsa000621.06507768
46Hematopoietic cell lineage_Homo sapiens_hsa046401.06494131
47Parkinsons disease_Homo sapiens_hsa050121.04707687
48Hepatitis B_Homo sapiens_hsa051611.04433672
49Antigen processing and presentation_Homo sapiens_hsa046121.03126533
50Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.99978586
51Oocyte meiosis_Homo sapiens_hsa041140.98269859
52Thyroid cancer_Homo sapiens_hsa052160.96463841
53Influenza A_Homo sapiens_hsa051640.96094340
54Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.94305308
55B cell receptor signaling pathway_Homo sapiens_hsa046620.91312041
56Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.88564825
57Graft-versus-host disease_Homo sapiens_hsa053320.88464049
58Jak-STAT signaling pathway_Homo sapiens_hsa046300.88105444
59Phototransduction_Homo sapiens_hsa047440.87574712
60Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.87451128
61Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.85381821
62Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.83965203
63Olfactory transduction_Homo sapiens_hsa047400.83854348
64Selenocompound metabolism_Homo sapiens_hsa004500.82478988
65Leishmaniasis_Homo sapiens_hsa051400.81458037
66Purine metabolism_Homo sapiens_hsa002300.81235125
67Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.81199091
68Steroid biosynthesis_Homo sapiens_hsa001000.79410252
69Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.75348514
70Pyruvate metabolism_Homo sapiens_hsa006200.74973849
71TNF signaling pathway_Homo sapiens_hsa046680.74262370
72Toll-like receptor signaling pathway_Homo sapiens_hsa046200.73450643
73Apoptosis_Homo sapiens_hsa042100.71901653
74Legionellosis_Homo sapiens_hsa051340.71841584
75Butanoate metabolism_Homo sapiens_hsa006500.70562839
76Chronic myeloid leukemia_Homo sapiens_hsa052200.69472804
77RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.68628080
78Acute myeloid leukemia_Homo sapiens_hsa052210.67648206
79Sulfur relay system_Homo sapiens_hsa041220.64686831
80Toxoplasmosis_Homo sapiens_hsa051450.64675305
81Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.64278851
82Allograft rejection_Homo sapiens_hsa053300.63047348
83Ribosome_Homo sapiens_hsa030100.62843919
84Pancreatic cancer_Homo sapiens_hsa052120.61954929
85Glutathione metabolism_Homo sapiens_hsa004800.61334427
86Lysine degradation_Homo sapiens_hsa003100.61308511
87Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.60347433
88Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.58483868
89Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.58115262
90T cell receptor signaling pathway_Homo sapiens_hsa046600.57276112
91TGF-beta signaling pathway_Homo sapiens_hsa043500.56652960
92Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.55408406
93Osteoclast differentiation_Homo sapiens_hsa043800.54469561
94Prostate cancer_Homo sapiens_hsa052150.53349784
95Peroxisome_Homo sapiens_hsa041460.53177287
96Viral myocarditis_Homo sapiens_hsa054160.51894076
97Alcoholism_Homo sapiens_hsa050340.50712848
98Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.49071195
99Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.48749869
100Autoimmune thyroid disease_Homo sapiens_hsa053200.47946273
101FoxO signaling pathway_Homo sapiens_hsa040680.47076508
102Thyroid hormone signaling pathway_Homo sapiens_hsa049190.46941918
103Hepatitis C_Homo sapiens_hsa051600.46888955
104Platelet activation_Homo sapiens_hsa046110.45179616
105Metabolic pathways_Homo sapiens_hsa011000.44951766
106Ovarian steroidogenesis_Homo sapiens_hsa049130.44302740
107Alzheimers disease_Homo sapiens_hsa050100.44212724
108Glycosaminoglycan degradation_Homo sapiens_hsa005310.43021452
109Pathways in cancer_Homo sapiens_hsa052000.42367475
110Wnt signaling pathway_Homo sapiens_hsa043100.41875653
111Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.41825541
112Hippo signaling pathway_Homo sapiens_hsa043900.41380419
113Colorectal cancer_Homo sapiens_hsa052100.40293710
114Endometrial cancer_Homo sapiens_hsa052130.39837859
115Vitamin B6 metabolism_Homo sapiens_hsa007500.38440037
116Drug metabolism - other enzymes_Homo sapiens_hsa009830.37464958
117Chemokine signaling pathway_Homo sapiens_hsa040620.37451017
118Adherens junction_Homo sapiens_hsa045200.36885157
119Basal cell carcinoma_Homo sapiens_hsa052170.36586327
120Nitrogen metabolism_Homo sapiens_hsa009100.36498966
121Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.36387736
122Shigellosis_Homo sapiens_hsa051310.36351716
123Fatty acid metabolism_Homo sapiens_hsa012120.36217884
124SNARE interactions in vesicular transport_Homo sapiens_hsa041300.35349553
125Tuberculosis_Homo sapiens_hsa051520.34176231
126Leukocyte transendothelial migration_Homo sapiens_hsa046700.33985796
127Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.32482021
128Non-small cell lung cancer_Homo sapiens_hsa052230.31315663
129Proteoglycans in cancer_Homo sapiens_hsa052050.31080105
130Arachidonic acid metabolism_Homo sapiens_hsa005900.29804437
131Regulation of autophagy_Homo sapiens_hsa041400.29769722
132Dorso-ventral axis formation_Homo sapiens_hsa043200.29543995
133N-Glycan biosynthesis_Homo sapiens_hsa005100.28670992
134Circadian rhythm_Homo sapiens_hsa047100.27623929
135Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.27604877
136Proteasome_Homo sapiens_hsa030500.27465783
137Neurotrophin signaling pathway_Homo sapiens_hsa047220.26414390
138Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.25333023
139African trypanosomiasis_Homo sapiens_hsa051430.25158178
140Steroid hormone biosynthesis_Homo sapiens_hsa001400.25007189
141Notch signaling pathway_Homo sapiens_hsa043300.24998971
142Type I diabetes mellitus_Homo sapiens_hsa049400.24213806
143Nicotine addiction_Homo sapiens_hsa050330.18486481
144Taste transduction_Homo sapiens_hsa047420.18369970
145Fatty acid degradation_Homo sapiens_hsa000710.17593007
146Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.17365957
1472-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.16797707
148Maturity onset diabetes of the young_Homo sapiens_hsa049500.16018340
149Melanoma_Homo sapiens_hsa052180.15802711
150Ether lipid metabolism_Homo sapiens_hsa005650.14262597
151Hedgehog signaling pathway_Homo sapiens_hsa043400.13965268
152Primary bile acid biosynthesis_Homo sapiens_hsa001200.13900027
153Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.12748808
154Chemical carcinogenesis_Homo sapiens_hsa052040.10742435
155Biosynthesis of amino acids_Homo sapiens_hsa012300.09042252
156Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.08995476

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