CCDC150

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1reproduction (GO:0000003)9.94446488
2motile cilium assembly (GO:0044458)9.50586289
3spermatid development (GO:0007286)8.92738461
4cilium movement (GO:0003341)8.62839984
5epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)8.00181847
6piRNA metabolic process (GO:0034587)7.66405113
7regulation of cilium movement (GO:0003352)7.62773539
8single fertilization (GO:0007338)7.61551581
9male meiosis (GO:0007140)7.55881138
10synaptonemal complex organization (GO:0070193)7.06857655
11synaptonemal complex assembly (GO:0007130)6.91844874
12sperm capacitation (GO:0048240)6.86593241
13fertilization (GO:0009566)6.29860528
14microtubule depolymerization (GO:0007019)6.26762701
15spermatogenesis (GO:0007283)5.94971293
16male gamete generation (GO:0048232)5.93395262
17negative regulation of inclusion body assembly (GO:0090084)5.85042707
18spermatid nucleus differentiation (GO:0007289)5.63727878
19organic cation transport (GO:0015695)5.50552660
20gamete generation (GO:0007276)5.47494211
21ventricular system development (GO:0021591)5.40699114
22cellular process involved in reproduction in multicellular organism (GO:0022412)5.09987776
23germ cell development (GO:0007281)5.06936046
24DNA methylation involved in gamete generation (GO:0043046)5.03310082
25chromosome organization involved in meiosis (GO:0070192)5.01777502
26regulation of inclusion body assembly (GO:0090083)4.96079797
27calcium ion-dependent exocytosis (GO:0017156)4.94177902
28male meiosis I (GO:0007141)4.85366463
29cell recognition (GO:0008037)4.84411103
30meiotic chromosome segregation (GO:0045132)4.65182322
31meiotic nuclear division (GO:0007126)4.55885407
32microtubule severing (GO:0051013)4.41545495
33regulation of microtubule-based movement (GO:0060632)4.35814455
34multicellular organismal reproductive process (GO:0048609)4.29249891
35monoubiquitinated protein deubiquitination (GO:0035520)4.22080710
36negative regulation of DNA-dependent DNA replication (GO:2000104)4.20435355
37single strand break repair (GO:0000012)4.19857063
38replication fork processing (GO:0031297)4.14402033
39behavioral response to nicotine (GO:0035095)4.10716320
40glycerol ether metabolic process (GO:0006662)4.03774981
41centriole assembly (GO:0098534)4.01593478
42reciprocal meiotic recombination (GO:0007131)3.98850081
43reciprocal DNA recombination (GO:0035825)3.98850081
44meiosis I (GO:0007127)3.93717354
45DNA double-strand break processing (GO:0000729)3.90301370
46seminiferous tubule development (GO:0072520)3.88474090
47chromatin remodeling at centromere (GO:0031055)3.75524447
48resolution of meiotic recombination intermediates (GO:0000712)3.75038308
49regulation of DNA endoreduplication (GO:0032875)3.74864357
50chromosome condensation (GO:0030261)3.74590446
51left/right pattern formation (GO:0060972)3.73286283
52ether metabolic process (GO:0018904)3.72997619
53chaperone-mediated protein complex assembly (GO:0051131)3.72564746
54meiotic cell cycle (GO:0051321)3.68181795
55protein K11-linked deubiquitination (GO:0035871)3.58759242
56DNA packaging (GO:0006323)3.55445858
57regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.55280929
58regulation of mitotic spindle checkpoint (GO:1903504)3.55280929
59regulation of nuclear cell cycle DNA replication (GO:0033262)3.55102883
60kinetochore organization (GO:0051383)3.54462072
61DNA replication checkpoint (GO:0000076)3.53433706
62centriole replication (GO:0007099)3.52422085
63recombinational repair (GO:0000725)3.50967597
64CENP-A containing nucleosome assembly (GO:0034080)3.49657024
65double-strand break repair via homologous recombination (GO:0000724)3.48834364
66microtubule polymerization or depolymerization (GO:0031109)3.45244975
67regulation of meiosis I (GO:0060631)3.43976702
68protein polyglutamylation (GO:0018095)3.39133291
69multicellular organismal development (GO:0007275)3.39098340
70axoneme assembly (GO:0035082)3.34982026
71genitalia morphogenesis (GO:0035112)3.33478381
72regulation of spindle checkpoint (GO:0090231)3.30972359
73protein localization to cilium (GO:0061512)3.27844603
74maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.25888138
75cilium organization (GO:0044782)3.22723295
76sexual reproduction (GO:0019953)3.21376728
77nucleoside diphosphate phosphorylation (GO:0006165)3.19922772
78fucose catabolic process (GO:0019317)3.19031026
79L-fucose metabolic process (GO:0042354)3.19031026
80L-fucose catabolic process (GO:0042355)3.19031026
81regulation of centriole replication (GO:0046599)3.13812866
82kinetochore assembly (GO:0051382)3.12903924
83synapsis (GO:0007129)3.12629279
84DNA replication-dependent nucleosome organization (GO:0034723)3.11615152
85DNA replication-dependent nucleosome assembly (GO:0006335)3.11615152
86intraciliary transport (GO:0042073)3.10613379
87GTP biosynthetic process (GO:0006183)3.10138039
88cilium assembly (GO:0042384)3.09374717
89meiotic cell cycle process (GO:1903046)3.08328250
90nuclear pore complex assembly (GO:0051292)3.03488258
91nucleus organization (GO:0006997)3.03163991
92detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.01704906
93protein refolding (GO:0042026)3.01057489
94DNA synthesis involved in DNA repair (GO:0000731)3.00852109
95cellular component assembly involved in morphogenesis (GO:0010927)3.00013591
96somatic diversification of immune receptors via somatic mutation (GO:0002566)2.99480672
97somatic hypermutation of immunoglobulin genes (GO:0016446)2.99480672
98microtubule-based movement (GO:0007018)2.97153466
99protein K6-linked ubiquitination (GO:0085020)2.96324736
100mitotic sister chromatid cohesion (GO:0007064)2.91426732
101gene silencing by RNA (GO:0031047)2.91201043
102nonmotile primary cilium assembly (GO:0035058)2.89328413
103cilium morphogenesis (GO:0060271)2.86729725
104carnitine transport (GO:0015879)2.86305500
105amino-acid betaine transport (GO:0015838)2.86305500
106water-soluble vitamin biosynthetic process (GO:0042364)2.85519024
107UTP biosynthetic process (GO:0006228)2.79810081
108respiratory chain complex IV assembly (GO:0008535)2.78429420
109RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.78186938
110regulation of centrosome cycle (GO:0046605)2.77445874
111postreplication repair (GO:0006301)2.77203142
112glycolytic process (GO:0006096)2.75950980
113carnitine transmembrane transport (GO:1902603)2.75784311
114DNA strand renaturation (GO:0000733)2.75556429
115protein localization to kinetochore (GO:0034501)2.74792865
116polyol catabolic process (GO:0046174)2.72872215
117regulation of gene silencing by miRNA (GO:0060964)2.71291920
118regulation of gene silencing by RNA (GO:0060966)2.71291920
119regulation of posttranscriptional gene silencing (GO:0060147)2.71291920
120DNA recombination (GO:0006310)2.70947486
121response to pheromone (GO:0019236)2.70405204
122regulation of centrosome duplication (GO:0010824)2.70373578
123mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.69377686
124mitochondrial respiratory chain complex I assembly (GO:0032981)2.69377686
125NADH dehydrogenase complex assembly (GO:0010257)2.69377686
126nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.68476064
127tryptophan catabolic process (GO:0006569)2.67613501
128indole-containing compound catabolic process (GO:0042436)2.67613501
129indolalkylamine catabolic process (GO:0046218)2.67613501
130histone exchange (GO:0043486)2.66615439
131alditol metabolic process (GO:0019400)2.65398398
132kynurenine metabolic process (GO:0070189)2.63993618
133protein complex biogenesis (GO:0070271)2.62589801
134DNA catabolic process, exonucleolytic (GO:0000738)2.62559885
135exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.61748531
136mitotic sister chromatid segregation (GO:0000070)2.61050541
137negative regulation of translation, ncRNA-mediated (GO:0040033)2.59638786
138regulation of translation, ncRNA-mediated (GO:0045974)2.59638786
139negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.59638786
140lactate metabolic process (GO:0006089)2.59211211
141sister chromatid cohesion (GO:0007062)2.59177599
142DNA replication-independent nucleosome assembly (GO:0006336)2.59078106
143DNA replication-independent nucleosome organization (GO:0034724)2.59078106
144centrosome organization (GO:0051297)2.57628911
145DNA-dependent DNA replication (GO:0006261)2.57414728
146kidney morphogenesis (GO:0060993)2.56903686
147mitochondrial respiratory chain complex assembly (GO:0033108)2.56335426
148peptidyl-histidine modification (GO:0018202)2.55913268
149negative regulation of organelle assembly (GO:1902116)2.54896984
150double-strand break repair (GO:0006302)2.54840802
151indolalkylamine metabolic process (GO:0006586)2.54319769
152translesion synthesis (GO:0019985)2.53204905
153pseudouridine synthesis (GO:0001522)2.52982766
154retinal cone cell development (GO:0046549)2.52918293
155establishment of protein localization to mitochondrial membrane (GO:0090151)2.52480646
156positive regulation of macrophage activation (GO:0043032)2.52085415
157somite development (GO:0061053)2.51317726
158nuclear pore organization (GO:0006999)2.50971287
159attachment of spindle microtubules to kinetochore (GO:0008608)2.50941827
160spindle checkpoint (GO:0031577)2.49909148
161sister chromatid segregation (GO:0000819)2.48548501
162cytochrome complex assembly (GO:0017004)2.47271644
163interferon-gamma secretion (GO:0072643)2.47141494
164left/right axis specification (GO:0070986)2.47138461
165fusion of sperm to egg plasma membrane (GO:0007342)14.2659835
166cell wall macromolecule catabolic process (GO:0016998)13.6187613
167cell wall macromolecule metabolic process (GO:0044036)13.6187613
168cilium or flagellum-dependent cell motility (GO:0001539)12.3249057
169sperm motility (GO:0030317)12.2928348
170multicellular organism reproduction (GO:0032504)11.8675213
171sperm-egg recognition (GO:0035036)11.4337795
172acrosome assembly (GO:0001675)11.4330924
173plasma membrane fusion (GO:0045026)10.8248223
174acrosome reaction (GO:0007340)10.6701970
175axonemal dynein complex assembly (GO:0070286)10.2475936
176cell-cell recognition (GO:0009988)10.2244511
177epithelial cilium movement (GO:0003351)10.1274944
178binding of sperm to zona pellucida (GO:0007339)10.0491020

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse9.95733582
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.25483967
3BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.57116636
4E2F7_22180533_ChIP-Seq_HELA_Human3.23959702
5EZH2_22144423_ChIP-Seq_EOC_Human3.15404342
6GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.14113381
7SALL1_21062744_ChIP-ChIP_HESCs_Human3.00105984
8E2F4_17652178_ChIP-ChIP_JURKAT_Human2.85047653
9PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.82476030
10KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.71462035
11CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.66792015
12* FLI1_27457419_Chip-Seq_LIVER_Mouse2.57806977
13FOXM1_23109430_ChIP-Seq_U2OS_Human2.45456577
14* PCGF2_27294783_Chip-Seq_ESCs_Mouse2.42490396
15* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.35500258
16ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.33838721
17EWS_26573619_Chip-Seq_HEK293_Human2.31792939
18GABP_17652178_ChIP-ChIP_JURKAT_Human2.30059489
19EST1_17652178_ChIP-ChIP_JURKAT_Human2.29079316
20POU3F2_20337985_ChIP-ChIP_501MEL_Human2.14562584
21* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse2.13216259
22GBX2_23144817_ChIP-Seq_PC3_Human2.12319271
23KAP1_22055183_ChIP-Seq_ESCs_Mouse2.08776942
24IGF1R_20145208_ChIP-Seq_DFB_Human2.05826842
25VDR_22108803_ChIP-Seq_LS180_Human2.05406246
26HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.04730207
27STAT6_21828071_ChIP-Seq_BEAS2B_Human2.02907524
28KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse2.00766364
29TAF15_26573619_Chip-Seq_HEK293_Human1.96920110
30EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.93232377
31FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.88685555
32RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.87258628
33P300_19829295_ChIP-Seq_ESCs_Human1.84931836
34MYC_18940864_ChIP-ChIP_HL60_Human1.84536976
35E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.84442728
36GATA1_26923725_Chip-Seq_HPCs_Mouse1.84213592
37* CBX2_27304074_Chip-Seq_ESCs_Mouse1.82443866
38* PCGF2_27294783_Chip-Seq_NPCs_Mouse1.82021611
39ZNF274_21170338_ChIP-Seq_K562_Hela1.80830019
40* NFE2_27457419_Chip-Seq_LIVER_Mouse1.79180710
41ELK1_19687146_ChIP-ChIP_HELA_Human1.76868699
42TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.76711492
43CTBP1_25329375_ChIP-Seq_LNCAP_Human1.76356684
44GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.76180729
45* SUZ12_27294783_Chip-Seq_NPCs_Mouse1.75598492
46* STAT1_17558387_ChIP-Seq_HELA_Human1.72397976
47TAL1_26923725_Chip-Seq_HPCs_Mouse1.67055349
48MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.65133262
49ELK4_26923725_Chip-Seq_MESODERM_Mouse1.64327673
50IRF1_19129219_ChIP-ChIP_H3396_Human1.63304264
51* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.62569207
52WDR5_24793694_ChIP-Seq_LNCAP_Human1.60805600
53KDM2B_26808549_Chip-Seq_REH_Human1.59862764
54GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.55961729
55NOTCH1_21737748_ChIP-Seq_TLL_Human1.55371822
56ZFP57_27257070_Chip-Seq_ESCs_Mouse1.55281134
57ER_23166858_ChIP-Seq_MCF-7_Human1.55165021
58VDR_23849224_ChIP-Seq_CD4+_Human1.50193000
59CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.48647453
60MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.48634104
61* CRX_20693478_ChIP-Seq_RETINA_Mouse1.47469589
62MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.43758778
63* NANOG_18555785_Chip-Seq_ESCs_Mouse1.43197663
64BCAT_22108803_ChIP-Seq_LS180_Human1.42121521
65SOX2_22085726_ChIP-Seq_NPCs_Mouse1.41967841
66TP53_22573176_ChIP-Seq_HFKS_Human1.41310628
67UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.41145495
68CBP_20019798_ChIP-Seq_JUKART_Human1.41116671
69IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.41116671
70* OCT4_18555785_Chip-Seq_ESCs_Mouse1.41013430
71* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.40803682
72FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.39635172
73POU5F1_16153702_ChIP-ChIP_HESCs_Human1.38612485
74ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.38593011
75GATA3_21867929_ChIP-Seq_CD8_Mouse1.38310491
76* EZH2_27294783_Chip-Seq_NPCs_Mouse1.37982292
77FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.37274880
78* ETS1_20019798_ChIP-Seq_JURKAT_Human1.35533808
79SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.35141048
80* P53_22387025_ChIP-Seq_ESCs_Mouse1.34243073
81EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.34012149
82AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.33733461
83* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.33253880
84* CMYC_18555785_Chip-Seq_ESCs_Mouse1.32503234
85JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.32110929
86KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.31676690
87* P300_18555785_Chip-Seq_ESCs_Mouse1.31291735
88STAT3_23295773_ChIP-Seq_U87_Human1.31039245
89CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.31022592
90LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.28574309
91CTBP2_25329375_ChIP-Seq_LNCAP_Human1.28257384
92* KLF4_18555785_Chip-Seq_ESCs_Mouse1.27883449
93* GATA3_21867929_ChIP-Seq_TH1_Mouse1.26963941
94FLI1_21867929_ChIP-Seq_TH2_Mouse1.26329697
95TP63_19390658_ChIP-ChIP_HaCaT_Human1.25343786
96TCF4_23295773_ChIP-Seq_U87_Human1.25232882
97* EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.24664334
98MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.24042520
99GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.23685430
100* STAT3_18555785_Chip-Seq_ESCs_Mouse1.23317803
101KLF5_20875108_ChIP-Seq_MESCs_Mouse1.22898278
102* ESRRB_18555785_Chip-Seq_ESCs_Mouse1.22237315
103GF1_26923725_Chip-Seq_HPCs_Mouse1.21698667
104* SUZ12_18555785_Chip-Seq_ESCs_Mouse1.21205467
105FOXP3_21729870_ChIP-Seq_TREG_Human1.21192369
106SOX2_19829295_ChIP-Seq_ESCs_Human1.20728786
107NANOG_19829295_ChIP-Seq_ESCs_Human1.20728786
108* OCT4_21477851_ChIP-Seq_ESCs_Mouse1.20543297
109PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.20147880
110PADI4_21655091_ChIP-ChIP_MCF-7_Human1.19324880
111* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.19240267
112AR_25329375_ChIP-Seq_VCAP_Human1.17384961
113TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.16895381
114* SOX2_18555785_Chip-Seq_ESCs_Mouse1.16890363
115CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.16341932
116* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.16180042
117E2F1_21310950_ChIP-Seq_MCF-7_Human1.16073326
118P53_21459846_ChIP-Seq_SAOS-2_Human1.14641191
119RUNX1_26923725_Chip-Seq_HPCs_Mouse1.14190435
120FOXA1_25329375_ChIP-Seq_VCAP_Human1.13530746
121FOXA1_27270436_Chip-Seq_PROSTATE_Human1.13530746
122BMI1_23680149_ChIP-Seq_NPCS_Mouse1.13314211
123TCF4_22108803_ChIP-Seq_LS180_Human1.11763319
124SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.11258335
125FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.11157896
126* SMAD4_21799915_ChIP-Seq_A2780_Human1.10719241
127NR3C1_21868756_ChIP-Seq_MCF10A_Human1.10687561
128* CTCF_18555785_Chip-Seq_ESCs_Mouse1.10613874
129* PU1_27457419_Chip-Seq_LIVER_Mouse1.09274768
130PIAS1_25552417_ChIP-Seq_VCAP_Human1.07890260
131* SMAD3_21741376_ChIP-Seq_EPCs_Human1.07691305
132* E2F1_18555785_Chip-Seq_ESCs_Mouse1.07359074
133TOP2B_26459242_ChIP-Seq_MCF-7_Human1.06719623
134RNF2_27304074_Chip-Seq_NSC_Mouse1.06537341
135PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.06483966
136* SMAD1_18555785_Chip-Seq_ESCs_Mouse1.06126517
137* RUNX1_27457419_Chip-Seq_LIVER_Mouse1.05435381
138* SMAD4_21741376_ChIP-Seq_EPCs_Human1.05274818
139RUNX2_22187159_ChIP-Seq_PCA_Human1.04627319
140* NMYC_18555785_Chip-Seq_ESCs_Mouse1.04289615
141* ZFX_18555785_Chip-Seq_ESCs_Mouse1.04101395
142CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.03491692
143TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.03205688
144NFYB_21822215_ChIP-Seq_K562_Human1.03197664
145CREB1_15753290_ChIP-ChIP_HEK293T_Human1.02879908
146HOXB7_26014856_ChIP-Seq_BT474_Human1.02408186
147FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.01900462
148SPI1_26923725_Chip-Seq_HPCs_Mouse1.01573181
149FUS_26573619_Chip-Seq_HEK293_Human1.01271958
150REST_21632747_ChIP-Seq_MESCs_Mouse1.00875512
151SRF_21415370_ChIP-Seq_HL-1_Mouse1.00795332
152NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.00468990
153SOX9_26525672_Chip-Seq_HEART_Mouse0.99168347
154PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.99031196
155FOXA1_21572438_ChIP-Seq_LNCaP_Human0.98203741
156ESET_19884257_ChIP-Seq_ESCs_Mouse0.98083802
157GATA3_21878914_ChIP-Seq_MCF-7_Human0.97950985
158NCOR_22424771_ChIP-Seq_293T_Human0.96451359
159GF1B_26923725_Chip-Seq_HPCs_Mouse0.96141081
160RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.94891396
161POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.94782321
162TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94782321
163MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.94278034
164AUTS2_25519132_ChIP-Seq_293T-REX_Human0.94060825
165PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.93673065
166CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.93200507
167* SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.93108732
168TBL1_22424771_ChIP-Seq_293T_Human0.92997770
169AR_20517297_ChIP-Seq_VCAP_Human0.92942288
170RAD21_21589869_ChIP-Seq_MESCs_Mouse0.92503145
171SOX2_16153702_ChIP-ChIP_HESCs_Human0.92226485
172EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.91245117
173PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.91055296
174ERG_20517297_ChIP-Seq_VCAP_Human0.90636863
175KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.90318367

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive5.93055448
2MP0001929_abnormal_gametogenesis5.52027559
3MP0008877_abnormal_DNA_methylation4.88152235
4MP0002210_abnormal_sex_determination3.69087761
5MP0006292_abnormal_olfactory_placode3.61123674
6MP0002161_abnormal_fertility/fecundity3.23321396
7MP0001145_abnormal_male_reproductive3.11460083
8MP0002653_abnormal_ependyma_morphology3.11208506
9MP0000653_abnormal_sex_gland2.72314739
10MP0002938_white_spotting2.35572553
11MP0005623_abnormal_meninges_morphology2.30354328
12MP0005670_abnormal_white_adipose2.12579567
13MP0003195_calcinosis2.03544137
14MP0005410_abnormal_fertilization15.2490721
15MP0008057_abnormal_DNA_replication1.93236012
16MP0008058_abnormal_DNA_repair1.92131893
17MP0000372_irregular_coat_pigmentation1.79792589
18MP0004147_increased_porphyrin_level1.77890984
19MP0002102_abnormal_ear_morphology1.77395475
20MP0002160_abnormal_reproductive_system1.75144964
21MP0002282_abnormal_trachea_morphology1.72516878
22MP0002638_abnormal_pupillary_reflex1.61576143
23MP0000427_abnormal_hair_cycle1.50872738
24MP0010094_abnormal_chromosome_stability1.50596621
25MP0008789_abnormal_olfactory_epithelium1.49844604
26MP0000569_abnormal_digit_pigmentation1.48782882
27MP0001968_abnormal_touch/_nociception1.42110544
28MP0010030_abnormal_orbit_morphology1.40353379
29MP0000383_abnormal_hair_follicle1.39723376
30MP0001485_abnormal_pinna_reflex1.39091707
31MP0002837_dystrophic_cardiac_calcinosis1.31737288
32MP0004233_abnormal_muscle_weight1.30603893
33MP0005174_abnormal_tail_pigmentation1.30228489
34MP0001986_abnormal_taste_sensitivity1.25862948
35MP0001529_abnormal_vocalization1.25763170
36MP0008872_abnormal_physiological_respon1.23938763
37MP0004043_abnormal_pH_regulation1.22904794
38MP0000631_abnormal_neuroendocrine_gland1.20047928
39MP0003111_abnormal_nucleus_morphology1.19896241
40MP0003121_genomic_imprinting1.17650590
41MP0008875_abnormal_xenobiotic_pharmacok1.16768551
42MP0000647_abnormal_sebaceous_gland1.15898838
43MP0003880_abnormal_central_pattern1.12269736
44MP0004142_abnormal_muscle_tone1.10810791
45MP0005646_abnormal_pituitary_gland1.10712254
46MP0006276_abnormal_autonomic_nervous1.10198784
47MP0003950_abnormal_plasma_membrane1.08904590
48MP0002095_abnormal_skin_pigmentation1.07377268
49MP0005499_abnormal_olfactory_system1.06322637
50MP0005394_taste/olfaction_phenotype1.06322637
51MP0009379_abnormal_foot_pigmentation1.05862517
52MP0002876_abnormal_thyroid_physiology1.05290114
53MP0003646_muscle_fatigue1.05148054
54MP0009046_muscle_twitch1.04486356
55MP0001188_hyperpigmentation0.99819640
56MP0002234_abnormal_pharynx_morphology0.99818670
57MP0003567_abnormal_fetal_cardiomyocyte0.99736657
58MP0005195_abnormal_posterior_eye0.99700864
59MP0001765_abnormal_ion_homeostasis0.99347037
60MP0004885_abnormal_endolymph0.98792731
61MP0005645_abnormal_hypothalamus_physiol0.98451615
62MP0001286_abnormal_eye_development0.97340636
63MP0002272_abnormal_nervous_system0.97006087
64MP0002233_abnormal_nose_morphology0.95980869
65MP0008995_early_reproductive_senescence0.94771437
66MP0005647_abnormal_sex_gland0.92224517
67MP0000778_abnormal_nervous_system0.91792193
68MP0005389_reproductive_system_phenotype0.91526909
69MP0000049_abnormal_middle_ear0.89723579
70MP0003283_abnormal_digestive_organ0.89457171
71MP0002751_abnormal_autonomic_nervous0.87956746
72MP0009745_abnormal_behavioral_response0.86727127
73MP0003136_yellow_coat_color0.85001002
74MP0003786_premature_aging0.84335501
75MP0001486_abnormal_startle_reflex0.82111968
76MP0003938_abnormal_ear_development0.81919773
77MP0005084_abnormal_gallbladder_morpholo0.79770293
78MP0006035_abnormal_mitochondrial_morpho0.78628770
79MP0002557_abnormal_social/conspecific_i0.77787649
80MP0002163_abnormal_gland_morphology0.77528463
81MP0001293_anophthalmia0.74506287
82MP0008007_abnormal_cellular_replicative0.73457335
83MP0005377_hearing/vestibular/ear_phenot0.71870300
84MP0003878_abnormal_ear_physiology0.71870300
85MP0003115_abnormal_respiratory_system0.64712564
86MP0003011_delayed_dark_adaptation0.59911827
87MP0001119_abnormal_female_reproductive0.59602344
88MP0001984_abnormal_olfaction0.58395248
89MP0003077_abnormal_cell_cycle0.57429222
90MP0009697_abnormal_copulation0.55548268
91MP0003699_abnormal_female_reproductive0.55000079
92MP0000358_abnormal_cell_content/0.53172430
93MP0010307_abnormal_tumor_latency0.53168281
94MP0002928_abnormal_bile_duct0.51044471
95MP0003890_abnormal_embryonic-extraembry0.51013313
96MP0005253_abnormal_eye_physiology0.50591741
97MP0005551_abnormal_eye_electrophysiolog0.50164829
98MP0001730_embryonic_growth_arrest0.49345933
99MP0002269_muscular_atrophy0.45134423
100MP0001764_abnormal_homeostasis0.44924390
101MP0000566_synostosis0.44275558
102MP0005636_abnormal_mineral_homeostasis0.44072212
103MP0005391_vision/eye_phenotype0.42876116
104MP0004957_abnormal_blastocyst_morpholog0.42262150
105MP0004808_abnormal_hematopoietic_stem0.41655088
106MP0004133_heterotaxia0.40621688
107MP0001324_abnormal_eye_pigmentation0.40298723
108MP0005397_hematopoietic_system_phenotyp0.39727098
109MP0001545_abnormal_hematopoietic_system0.39727098
110MP0002084_abnormal_developmental_patter0.38883410
111MP0000313_abnormal_cell_death0.38332220
112MP0008932_abnormal_embryonic_tissue0.38075004
113MP0001672_abnormal_embryogenesis/_devel0.37994537
114MP0005380_embryogenesis_phenotype0.37994537
115MP0004036_abnormal_muscle_relaxation0.37669942
116MP0003693_abnormal_embryo_hatching0.34838880
117MP0002132_abnormal_respiratory_system0.32348315
118MP0001697_abnormal_embryo_size0.32043177
119MP0004084_abnormal_cardiac_muscle0.31567212
120MP0000432_abnormal_head_morphology0.31536663
121MP0003984_embryonic_growth_retardation0.30455131
122MP0006072_abnormal_retinal_apoptosis0.29482913
123MP0002092_abnormal_eye_morphology0.27793179
124MP0002088_abnormal_embryonic_growth/wei0.26986206
125MP0004019_abnormal_vitamin_homeostasis0.25950539
126MP0009250_abnormal_appendicular_skeleto0.24695471
127MP0002085_abnormal_embryonic_tissue0.24309487
128MP0003861_abnormal_nervous_system0.24050775
129MP0004197_abnormal_fetal_growth/weight/0.23990676
130MP0003937_abnormal_limbs/digits/tail_de0.23885045
131MP0003942_abnormal_urinary_system0.23567787
132MP0002405_respiratory_system_inflammati0.22478869
133MP0003943_abnormal_hepatobiliary_system0.22241304
134MP0002109_abnormal_limb_morphology0.20085444
135MP0002080_prenatal_lethality0.20015456
136MP0006036_abnormal_mitochondrial_physio0.19984977
137MP0009115_abnormal_fat_cell0.18431608
138MP0003119_abnormal_digestive_system0.18176473
139MP0009278_abnormal_bone_marrow0.17982526
140MP0001919_abnormal_reproductive_system0.17412188
141MP0003718_maternal_effect0.16785192
142MP0002736_abnormal_nociception_after0.16718298
143MP0005666_abnormal_adipose_tissue0.16578503
144MP0005388_respiratory_system_phenotype0.16386602
145MP0002133_abnormal_respiratory_system0.16386602
146MP0002169_no_abnormal_phenotype0.16314834
147MP0002873_normal_phenotype0.16248783
148MP0004134_abnormal_chest_morphology0.15516560
149MP0004742_abnormal_vestibular_system0.14899519
150MP0000534_abnormal_ureter_morphology0.14195150
151MP0003787_abnormal_imprinting0.14083826

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)9.34226560
2Abnormal respiratory motile cilium morphology (HP:0005938)9.15367121
3Abnormal respiratory epithelium morphology (HP:0012253)9.15367121
4Abnormal ciliary motility (HP:0012262)7.89392636
5Rhinitis (HP:0012384)7.66876644
6Chronic bronchitis (HP:0004469)6.94111634
7Nasal polyposis (HP:0100582)6.11340328
8Infertility (HP:0000789)5.71016388
9Abnormality of the nasal mucosa (HP:0000433)4.96168322
10Bronchiectasis (HP:0002110)4.47624646
11Bronchitis (HP:0012387)4.32955949
12Nephronophthisis (HP:0000090)4.16554588
13Male infertility (HP:0003251)3.77258507
14Recurrent sinusitis (HP:0011108)3.62773196
15Chromsome breakage (HP:0040012)3.61821074
16Chromosomal breakage induced by crosslinking agents (HP:0003221)3.57862333
17Abnormal spermatogenesis (HP:0008669)3.47885416
18Aplasia/Hypoplasia of the uvula (HP:0010293)3.21842886
19Abnormality of the labia minora (HP:0012880)3.20005428
20Abnormality of the ileum (HP:0001549)3.17981462
21Recurrent otitis media (HP:0000403)3.17647370
22Abnormality of the renal medulla (HP:0100957)3.17251849
23Meckel diverticulum (HP:0002245)3.15070605
24Birth length less than 3rd percentile (HP:0003561)3.08459158
25Tubulointerstitial nephritis (HP:0001970)3.01807163
26Medial flaring of the eyebrow (HP:0010747)2.95476148
27Congenital stationary night blindness (HP:0007642)2.94268549
28Abnormality of chromosome stability (HP:0003220)2.91930358
29Colon cancer (HP:0003003)2.80847667
30Abnormality of midbrain morphology (HP:0002418)2.76815888
31Molar tooth sign on MRI (HP:0002419)2.76815888
32Ectopic kidney (HP:0000086)2.61735976
33Recurrent bronchitis (HP:0002837)2.58852160
34Volvulus (HP:0002580)2.58488436
35Type II lissencephaly (HP:0007260)2.51998863
36Azoospermia (HP:0000027)2.50507721
37Duodenal stenosis (HP:0100867)2.48122843
38Small intestinal stenosis (HP:0012848)2.48122843
39Intestinal atresia (HP:0011100)2.43596879
40Abnormality of the preputium (HP:0100587)2.41131467
41Impulsivity (HP:0100710)2.40802696
42Sloping forehead (HP:0000340)2.40795113
43Tubular atrophy (HP:0000092)2.37721689
44Patellar aplasia (HP:0006443)2.33772573
45Abnormality of the duodenum (HP:0002246)2.32809323
46Gonadotropin excess (HP:0000837)2.26289622
47Attenuation of retinal blood vessels (HP:0007843)2.26114686
48Cerebellar dysplasia (HP:0007033)2.25616047
49Sclerocornea (HP:0000647)2.25453378
50Tubulointerstitial abnormality (HP:0001969)2.24057996
51Oligodactyly (hands) (HP:0001180)2.21544035
52Clubbing of toes (HP:0100760)2.21313917
53Triphalangeal thumb (HP:0001199)2.20821742
54Pendular nystagmus (HP:0012043)2.20694137
55Abnormality of the pons (HP:0007361)2.18805895
56Abolished electroretinogram (ERG) (HP:0000550)2.18416611
57Hypoplasia of the pons (HP:0012110)2.17906212
58Absent thumb (HP:0009777)2.17594212
59Aplasia/Hypoplasia of the patella (HP:0006498)2.17388297
60Preaxial hand polydactyly (HP:0001177)2.16936956
61Duplicated collecting system (HP:0000081)2.14650505
62Anencephaly (HP:0002323)2.14627090
63Postaxial foot polydactyly (HP:0001830)2.13551046
64Fibular hypoplasia (HP:0003038)2.12271678
65Abnormality of the carotid arteries (HP:0005344)2.12161264
66Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.07235700
67Abnormality of the renal collecting system (HP:0004742)2.03684094
68Small hand (HP:0200055)2.03082563
69Dandy-Walker malformation (HP:0001305)2.02315699
70Abnormal lung lobation (HP:0002101)2.02065928
71Aplasia/Hypoplasia of the sternum (HP:0006714)2.01507452
72Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.3160465
73Dynein arm defect of respiratory motile cilia (HP:0012255)13.0276530
74Absent/shortened dynein arms (HP:0200106)13.0276530
75Congenital primary aphakia (HP:0007707)1.98928453
76Hyperglycinuria (HP:0003108)1.96793895
77Gait imbalance (HP:0002141)1.96006718
78Hyperglycinemia (HP:0002154)1.95659810
79Reticulocytopenia (HP:0001896)1.95499748
80Gastrointestinal atresia (HP:0002589)1.94854428
81Hypoplasia of the capital femoral epiphysis (HP:0003090)1.92203640
82Facial cleft (HP:0002006)1.91235919
83Congenital, generalized hypertrichosis (HP:0004540)1.90860235
84Abnormal rod and cone electroretinograms (HP:0008323)1.90398221
85Lissencephaly (HP:0001339)1.89778631
86Congenital hepatic fibrosis (HP:0002612)1.89143238
87Septo-optic dysplasia (HP:0100842)1.88297211
88Abnormality of alanine metabolism (HP:0010916)1.87910147
89Hyperalaninemia (HP:0003348)1.87910147
90Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.87910147
91Abnormality of the dental root (HP:0006486)1.86622521
92Taurodontia (HP:0000679)1.86622521
93Abnormality of permanent molar morphology (HP:0011071)1.86622521
94Hyperventilation (HP:0002883)1.85709228
95Increased CSF lactate (HP:0002490)1.85678621
96Acute necrotizing encephalopathy (HP:0006965)1.85225060
97Pancreatic fibrosis (HP:0100732)1.85105746
98Anophthalmia (HP:0000528)1.84850414
99Absent radius (HP:0003974)1.84487545
100Astigmatism (HP:0000483)1.83306596
101Chronic sinusitis (HP:0011109)1.82818708
102Aplasia/Hypoplasia of the tibia (HP:0005772)1.81081799
103Stage 5 chronic kidney disease (HP:0003774)1.80468154
104Abnormality of cochlea (HP:0000375)1.79791457
105Acute encephalopathy (HP:0006846)1.79668730
106Renal cortical cysts (HP:0000803)1.79197929
107Fair hair (HP:0002286)1.78356277
108Short ribs (HP:0000773)1.77828607
109Absent forearm bone (HP:0003953)1.77581700
110Aplasia involving forearm bones (HP:0009822)1.77581700
111True hermaphroditism (HP:0010459)1.74489544
112Abnormality of molar morphology (HP:0011070)1.74108189
113Abnormality of molar (HP:0011077)1.74108189
114Supernumerary spleens (HP:0009799)1.74036159
115Abnormality of serine family amino acid metabolism (HP:0010894)1.73808735
116Abnormality of glycine metabolism (HP:0010895)1.73808735
117Bony spicule pigmentary retinopathy (HP:0007737)1.73766763
118Bilateral microphthalmos (HP:0007633)1.73349729
119Nephrogenic diabetes insipidus (HP:0009806)1.73238385
120Absent epiphyses (HP:0010577)1.73175725
121Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.73175725
122Rib fusion (HP:0000902)1.71353644
123Abnormality of the renal cortex (HP:0011035)1.71034726
124Oligohydramnios (HP:0001562)1.70919769
125Abnormality of the dental pulp (HP:0006479)1.70264046
126Aganglionic megacolon (HP:0002251)1.70167556
127Progressive inability to walk (HP:0002505)1.68797458
128Inability to walk (HP:0002540)1.68230853
129Abnormality of dentin (HP:0010299)1.67817673
130Abnormal gallbladder physiology (HP:0012438)1.65278445
131Cholecystitis (HP:0001082)1.65278445
132Heterotopia (HP:0002282)1.64928620
133Postaxial hand polydactyly (HP:0001162)1.64716007
134Decreased central vision (HP:0007663)1.63827187
135Oculomotor apraxia (HP:0000657)1.60811306
136Median cleft lip (HP:0000161)1.59281449
137Abnormal drinking behavior (HP:0030082)1.58124017
138Polydipsia (HP:0001959)1.58124017
139Aplasia/Hypoplasia of the lens (HP:0008063)1.56858439
140Genital tract atresia (HP:0001827)1.55650045
141Cystic liver disease (HP:0006706)1.54555365
142Poor coordination (HP:0002370)1.53939707
143Tubulointerstitial fibrosis (HP:0005576)1.52555190
144Bile duct proliferation (HP:0001408)1.52249914
145Abnormal biliary tract physiology (HP:0012439)1.52249914
146Vaginal atresia (HP:0000148)1.52186040
147Tongue fasciculations (HP:0001308)1.50578071
148Chronic hepatic failure (HP:0100626)1.50060648
149Aplasia/Hypoplasia of the tongue (HP:0010295)1.48024114
150Dyschromatopsia (HP:0007641)1.46811790
151Microglossia (HP:0000171)1.45745004
152Absent frontal sinuses (HP:0002688)1.45508476
153Bell-shaped thorax (HP:0001591)1.43955391
154Pancreatic cysts (HP:0001737)1.42750197
155Renal dysplasia (HP:0000110)1.40601979
156Abnormality of renal excretion (HP:0011036)1.39471703
157Abnormality of the lower motor neuron (HP:0002366)1.37322631
158Spastic tetraparesis (HP:0001285)1.36240355
159Muscle fibrillation (HP:0010546)1.35115706
160Short thorax (HP:0010306)1.34973761
161Asymmetric septal hypertrophy (HP:0001670)1.34233046
162Aplasia/Hypoplasia of the fibula (HP:0006492)1.32961017
163Abnormality of saccadic eye movements (HP:0000570)1.32771454
164Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.32732425
165Optic nerve hypoplasia (HP:0000609)1.28881692
166Bundle branch block (HP:0011710)1.28040816
167J-shaped sella turcica (HP:0002680)1.27971303
168Papillary thyroid carcinoma (HP:0002895)1.27771496
169Abnormality of ocular smooth pursuit (HP:0000617)1.27103698
170Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.26504611
171Transposition of the great arteries (HP:0001669)1.26045650
172Abnormal connection of the cardiac segments (HP:0011545)1.26045650
173Abnormal ventriculo-arterial connection (HP:0011563)1.26045650
174Amyotrophic lateral sclerosis (HP:0007354)1.24195191
175Type 2 muscle fiber atrophy (HP:0003554)1.21123354

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK49.02989896
2PDK39.02989896
3PDK25.87517724
4TESK14.41769278
5FRK3.98297598
6PRKD33.94907310
7ZAK3.15478634
8ICK3.10255467
9WNK32.56141907
10MKNK22.34355610
11NUAK12.22372496
12PNCK2.20354582
13ADRBK22.15110639
14PTK2B2.07199898
15WNK41.81976785
16NEK21.81306708
17STK391.80532838
18INSRR1.72298222
19MAP4K21.65871815
20MKNK11.63550892
21TNIK1.62657173
22OXSR11.57732177
23TLK11.54287395
24VRK11.37711648
25PLK21.31791778
26PLK41.28216036
27TGFBR11.23554920
28NEK11.23342013
29STK381.18336201
30MAPK131.17083312
31SRPK11.14923475
32MAP3K41.11213384
33VRK21.09289081
34STK38L1.09264434
35TTK1.08197848
36TAF11.05682798
37MAPK151.03279201
38WEE10.98814513
39TRIM280.97235580
40TAOK30.96119284
41DYRK1B0.94765698
42TSSK60.93504224
43IRAK10.91063166
44CDC70.89079255
45NME10.88794677
46STK30.88696916
47PDK10.85183270
48DYRK30.80604110
49CHEK20.78557668
50DYRK20.78003160
51CDK190.76074353
52FGFR20.75325787
53TIE10.75007249
54LMTK20.73688599
55BRSK20.72622542
56ADRBK10.72244179
57WNK10.68071283
58PASK0.67972314
59EIF2AK30.67649539
60CSNK1G10.67510866
61CHEK10.64164927
62MST40.62910239
63PRKCE0.62727684
64ATR0.59813306
65CCNB10.58854319
66ACVR1B0.57666052
67TYRO30.57113391
68NLK0.54843515
69MAP2K60.54735039
70CDK120.52871799
71PAK30.52296716
72CSNK1G20.51435663
73TESK20.50567138
74PLK10.46325824
75MET0.45892397
76CAMK1D0.44933071
77NEK60.44434962
78DAPK20.44010335
79CSNK1G30.43457522
80EPHA40.43402179
81TXK0.43061293
82PAK10.42701678
83BUB10.39824738
84PRKCI0.39602650
85AKT30.39345983
86ATM0.39025164
87CDK80.38924880
88CSNK1A1L0.35733172
89BCR0.34842687
90BMPR1B0.33941292
91ERBB30.32533765
92RPS6KA50.32397985
93PIK3CA0.32368703
94BRSK10.32242156
95TEC0.31787477
96CAMK1G0.30225551
97BRD40.29544519
98PRKCG0.27833836
99STK160.27816604
100PAK20.27608807
101MUSK0.25263808
102PDPK10.25110446
103CDK40.24245293
104MAP2K70.22587061
105MTOR0.22403724
106IRAK20.22341126
107MARK30.21368002
108PINK10.21260128
109BRAF0.20781278
110MAP3K30.19986544
111AURKA0.18310709
112YES10.18144280
113PKN10.17761558
114AURKB0.16183084
115RPS6KB10.15923841
116STK100.15026294
117CSNK1D0.14940604
118CDK20.14892195
119PRKAA10.14521098
120EEF2K0.14498864
121CSNK2A10.13868190
122LATS10.13706345
123PAK40.13655130
124CDK10.13045850
125PLK30.12848618
126CSNK2A20.12798007
127PRKG20.11689051
128GSK3B0.09085748
129RPS6KA10.08198855
130STK240.06660608
131ZAP700.06627748
132RIPK40.06220217
133CDK30.05926344
134EIF2AK20.05612211
135CSNK1E0.04555320
136STK110.04377196
137MAP2K20.04222718
138PRKDC0.04033229
139GRK10.03263109
140NTRK20.02985680
141PBK0.01836647
142PRKG10.01796234
143PIM10.01493446
144MELK0.01278242
145GSK3A0.01245131
146EGFR0.00845849
147PIK3CG0.00404515
148MAPK100.00093778
149MAPKAPK5-0.0042607
150CASK-0.0028695
151MAPK1-0.0016243
152RIPK1-0.0003818

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007505.02869323
2Glycolysis / Gluconeogenesis_Homo sapiens_hsa000104.21602551
3Fatty acid biosynthesis_Homo sapiens_hsa000613.40165233
4Basal transcription factors_Homo sapiens_hsa030223.39314113
5Pyruvate metabolism_Homo sapiens_hsa006203.38183214
6Fanconi anemia pathway_Homo sapiens_hsa034602.65376735
7Propanoate metabolism_Homo sapiens_hsa006402.60763516
8alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.41961517
9Linoleic acid metabolism_Homo sapiens_hsa005912.39251417
10Protein export_Homo sapiens_hsa030602.33092966
11Glucagon signaling pathway_Homo sapiens_hsa049222.30503719
12Pentose phosphate pathway_Homo sapiens_hsa000302.27692891
13Selenocompound metabolism_Homo sapiens_hsa004502.25147620
14Glycosaminoglycan degradation_Homo sapiens_hsa005312.12303848
15Oocyte meiosis_Homo sapiens_hsa041142.05668594
16Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.00921210
17One carbon pool by folate_Homo sapiens_hsa006701.99199362
18Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.98712774
19Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.98145887
20RNA polymerase_Homo sapiens_hsa030201.96042654
21Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.94729871
22Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.93614604
23Phototransduction_Homo sapiens_hsa047441.88219786
24RNA transport_Homo sapiens_hsa030131.85877354
25Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.80407958
26Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.79289480
27Butanoate metabolism_Homo sapiens_hsa006501.79217403
28Glycerolipid metabolism_Homo sapiens_hsa005611.75855664
29Dorso-ventral axis formation_Homo sapiens_hsa043201.71190587
30Oxidative phosphorylation_Homo sapiens_hsa001901.69267440
31Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.64233366
32Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.55851151
33Nitrogen metabolism_Homo sapiens_hsa009101.55430004
34Carbohydrate digestion and absorption_Homo sapiens_hsa049731.54089498
35Fructose and mannose metabolism_Homo sapiens_hsa000511.53373323
36Huntingtons disease_Homo sapiens_hsa050161.52945595
37Purine metabolism_Homo sapiens_hsa002301.52641116
38Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.51083074
39mRNA surveillance pathway_Homo sapiens_hsa030151.45070036
40Mineral absorption_Homo sapiens_hsa049781.42837012
41Parkinsons disease_Homo sapiens_hsa050121.41805846
42Tryptophan metabolism_Homo sapiens_hsa003801.41285445
43Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.40483414
44Carbon metabolism_Homo sapiens_hsa012001.38394415
45Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.34212447
46Glycerophospholipid metabolism_Homo sapiens_hsa005641.33880206
47Caffeine metabolism_Homo sapiens_hsa002321.33602603
48Cysteine and methionine metabolism_Homo sapiens_hsa002701.33254397
49Homologous recombination_Homo sapiens_hsa034401.32647868
50Antigen processing and presentation_Homo sapiens_hsa046121.30850342
51Ribosome_Homo sapiens_hsa030101.30799712
52Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.29555423
53PPAR signaling pathway_Homo sapiens_hsa033201.27394221
54Primary bile acid biosynthesis_Homo sapiens_hsa001201.21450074
55Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.21048835
56Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.19836447
57Maturity onset diabetes of the young_Homo sapiens_hsa049501.16317054
58Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.14798703
59Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.12081494
60Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.10109300
61Ether lipid metabolism_Homo sapiens_hsa005651.08665321
62Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.06217337
63Nicotine addiction_Homo sapiens_hsa050331.04426881
64Cardiac muscle contraction_Homo sapiens_hsa042601.02994797
65Cell cycle_Homo sapiens_hsa041101.00415350
66Retinol metabolism_Homo sapiens_hsa008300.99790544
67Hedgehog signaling pathway_Homo sapiens_hsa043400.99633354
68Glutathione metabolism_Homo sapiens_hsa004800.99544907
69Biosynthesis of amino acids_Homo sapiens_hsa012300.99227185
70Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.98258251
71Olfactory transduction_Homo sapiens_hsa047400.97801306
72Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.97618404
73Amphetamine addiction_Homo sapiens_hsa050310.97580511
74Peroxisome_Homo sapiens_hsa041460.97487301
75beta-Alanine metabolism_Homo sapiens_hsa004100.96729341
76Steroid biosynthesis_Homo sapiens_hsa001000.96484691
77Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.91900134
78Steroid hormone biosynthesis_Homo sapiens_hsa001400.90240495
79Pyrimidine metabolism_Homo sapiens_hsa002400.89448872
80DNA replication_Homo sapiens_hsa030300.87656248
81Pentose and glucuronate interconversions_Homo sapiens_hsa000400.86741420
82Inositol phosphate metabolism_Homo sapiens_hsa005620.84594285
83Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.78989502
84Renin-angiotensin system_Homo sapiens_hsa046140.77758707
85Arachidonic acid metabolism_Homo sapiens_hsa005900.77129601
86Lysine degradation_Homo sapiens_hsa003100.76702926
87Fatty acid degradation_Homo sapiens_hsa000710.73514980
88Protein digestion and absorption_Homo sapiens_hsa049740.73237406
89Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.72668835
90Legionellosis_Homo sapiens_hsa051340.71046994
91Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.70407867
92Alzheimers disease_Homo sapiens_hsa050100.69827547
93Fatty acid metabolism_Homo sapiens_hsa012120.69578532
94Renin secretion_Homo sapiens_hsa049240.66798503
95Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.65130976
96Proteasome_Homo sapiens_hsa030500.64300035
97Sulfur relay system_Homo sapiens_hsa041220.64205904
98Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.62149233
99Phosphatidylinositol signaling system_Homo sapiens_hsa040700.61455380
100RNA degradation_Homo sapiens_hsa030180.60756092
101Fat digestion and absorption_Homo sapiens_hsa049750.59823090
102Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.59584492
103Base excision repair_Homo sapiens_hsa034100.58483604
104Nucleotide excision repair_Homo sapiens_hsa034200.57461006
105Regulation of autophagy_Homo sapiens_hsa041400.56920930
106Spliceosome_Homo sapiens_hsa030400.54068176
107Chemical carcinogenesis_Homo sapiens_hsa052040.53670119
108Insulin secretion_Homo sapiens_hsa049110.53633628
109Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.53304909
110Systemic lupus erythematosus_Homo sapiens_hsa053220.51665230
111Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.51110942
112Non-homologous end-joining_Homo sapiens_hsa034500.51009132
113Metabolic pathways_Homo sapiens_hsa011000.48710310
114Calcium signaling pathway_Homo sapiens_hsa040200.47789318
115Thyroid hormone synthesis_Homo sapiens_hsa049180.47051113
116Thyroid hormone signaling pathway_Homo sapiens_hsa049190.46608575
117Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.46334014
118Mismatch repair_Homo sapiens_hsa034300.45722394
119Histidine metabolism_Homo sapiens_hsa003400.44796613
120cGMP-PKG signaling pathway_Homo sapiens_hsa040220.43541831
121Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.43198059
122Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.42992754
123N-Glycan biosynthesis_Homo sapiens_hsa005100.41125712
124Arginine and proline metabolism_Homo sapiens_hsa003300.40990905
125Basal cell carcinoma_Homo sapiens_hsa052170.40888016
126Estrogen signaling pathway_Homo sapiens_hsa049150.40643078
127Serotonergic synapse_Homo sapiens_hsa047260.39926120
128Morphine addiction_Homo sapiens_hsa050320.38916732
129Central carbon metabolism in cancer_Homo sapiens_hsa052300.38893889
130ABC transporters_Homo sapiens_hsa020100.36631808
131Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.35838097
132TGF-beta signaling pathway_Homo sapiens_hsa043500.34596692
133Fatty acid elongation_Homo sapiens_hsa000620.34155427
134Hippo signaling pathway_Homo sapiens_hsa043900.34066188
135Epstein-Barr virus infection_Homo sapiens_hsa051690.34021850
136Adipocytokine signaling pathway_Homo sapiens_hsa049200.32644947
137Cyanoamino acid metabolism_Homo sapiens_hsa004600.29991329
138Collecting duct acid secretion_Homo sapiens_hsa049660.27975662
139Wnt signaling pathway_Homo sapiens_hsa043100.25184584
140Viral carcinogenesis_Homo sapiens_hsa052030.23251887
141Endocytosis_Homo sapiens_hsa041440.22812231
142p53 signaling pathway_Homo sapiens_hsa041150.22671798
143Long-term potentiation_Homo sapiens_hsa047200.21816173
144AMPK signaling pathway_Homo sapiens_hsa041520.20284117
145Bile secretion_Homo sapiens_hsa049760.20179310
146cAMP signaling pathway_Homo sapiens_hsa040240.16591603
147Vascular smooth muscle contraction_Homo sapiens_hsa042700.15314786
148Vitamin digestion and absorption_Homo sapiens_hsa049770.13957156
149Taste transduction_Homo sapiens_hsa047420.13436390
150Pancreatic secretion_Homo sapiens_hsa049720.12474069
151Sphingolipid metabolism_Homo sapiens_hsa006000.09978799
152Herpes simplex infection_Homo sapiens_hsa051680.09836518
153HTLV-I infection_Homo sapiens_hsa051660.09684123

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